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Wyświetlanie 1-20 z 53
Tytuł:
GSI Treatment Preserves Protein Synthesis in C2C12 Myotubes.
Autorzy:
Huot JR; Laboratory of Systems Physiology, Department of Kinesiology, University of North Carolina at Charlotte, Charlotte, NC 28223, USA.; Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Thompson B; Laboratory of Systems Physiology, Department of Kinesiology, University of North Carolina at Charlotte, Charlotte, NC 28223, USA.
McMullen C; Laboratory of Systems Physiology, Department of Kinesiology, University of North Carolina at Charlotte, Charlotte, NC 28223, USA.
Marino JS; Laboratory of Systems Physiology, Department of Kinesiology, University of North Carolina at Charlotte, Charlotte, NC 28223, USA.
Arthur ST; Laboratory of Systems Physiology, Department of Kinesiology, University of North Carolina at Charlotte, Charlotte, NC 28223, USA.
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Źródło:
Cells [Cells] 2021 Jul 15; Vol. 10 (7). Date of Electronic Publication: 2021 Jul 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Amyloid Precursor Protein Secretases/*drug effects
Muscle Fibers, Skeletal/*drug effects
Protein Biosynthesis/*drug effects
Protein Synthesis Inhibitors/*pharmacology
Amyloid Precursor Protein Secretases/metabolism ; Animals ; Cell Differentiation/drug effects ; Mice ; Muscle Fibers, Skeletal/metabolism ; Muscle Proteins/metabolism ; Muscle, Skeletal/metabolism ; Myoblasts/drug effects ; Myoblasts/metabolism ; Protein Synthesis Inhibitors/metabolism ; Signal Transduction/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Quick Guide to Small-Molecule Inhibitors of Eukaryotic Protein Synthesis.
Autorzy:
Dmitriev SE; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, 119234, Russia. .; Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Moscow, 119234, Russia.; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991, Russia.
Vladimirov DO; Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Moscow, 119234, Russia.
Lashkevich KA; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, 119234, Russia.
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Źródło:
Biochemistry. Biokhimiia [Biochemistry (Mosc)] 2020 Nov; Vol. 85 (11), pp. 1389-1421.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Anti-Bacterial Agents*/chemistry
Anti-Bacterial Agents*/therapeutic use
Protein Synthesis Inhibitors*/chemistry
Protein Synthesis Inhibitors*/therapeutic use
Eukaryotic Cells/*metabolism
Protein Biosynthesis/*drug effects
Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Social Fear Memory Requires Two Stages of Protein Synthesis in Mice.
Autorzy:
Kornhuber J; Department of Psychiatry and Psychotherapy, Friedrich-Alexander University Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.
Zoicas I; Department of Psychiatry and Psychotherapy, Friedrich-Alexander University Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.; Department of Behavioural and Molecular Neurobiology, University of Regensburg, 93040 Regensburg, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2020 Aug 02; Vol. 21 (15). Date of Electronic Publication: 2020 Aug 02.
Typ publikacji:
Journal Article
MeSH Terms:
Anisomycin/*pharmacology
Fear/*drug effects
Memory/*drug effects
Protein Biosynthesis/*drug effects
Protein Synthesis Inhibitors/*pharmacology
Animals ; Anisomycin/administration & dosage ; Conditioning, Classical/drug effects ; Male ; Mice ; Protein Synthesis Inhibitors/administration & dosage ; Time Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Hypodermal responses to protein synthesis inhibition induce systemic developmental arrest and AMPK-dependent survival in Caenorhabditis elegans.
Autorzy:
Dalton HM; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, California, United States of America.; Dornsife College of Letters, Arts, and Sciences, University of Southern California, Los Angeles, California, United States of America.
Curran SP; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, California, United States of America.; Dornsife College of Letters, Arts, and Sciences, University of Southern California, Los Angeles, California, United States of America.; Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America.
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Źródło:
PLoS genetics [PLoS Genet] 2018 Jul 18; Vol. 14 (7), pp. e1007520. Date of Electronic Publication: 2018 Jul 18 (Print Publication: 2018).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
AMP-Activated Protein Kinases/*metabolism
Caenorhabditis elegans/*physiology
Caenorhabditis elegans Proteins/*metabolism
Gene Expression Regulation, Developmental/*physiology
Protein Biosynthesis/*physiology
AMP-Activated Protein Kinases/genetics ; Aging/drug effects ; Aging/physiology ; Animals ; Biological Evolution ; Caenorhabditis elegans Proteins/genetics ; Feeding Behavior/physiology ; Larva/physiology ; Longevity/drug effects ; Longevity/genetics ; Pharynx/physiology ; Protein Biosynthesis/drug effects ; Protein Biosynthesis/genetics ; Protein Synthesis Inhibitors/pharmacology ; RNA Interference ; Ribosomes/drug effects ; Ribosomes/genetics ; Ribosomes/metabolism ; Signal Transduction/genetics ; Subcutaneous Tissue/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Amino acid starvation sensing dampens IL-1β production by activating riboclustering and autophagy.
Autorzy:
Battu S; Department of Biotechnology and Bioinformatics, School of Life Sciences, University of Hyderabad, Hyderabad, Telangana, India.
Afroz S; Department of Biotechnology and Bioinformatics, School of Life Sciences, University of Hyderabad, Hyderabad, Telangana, India.
Giddaluru J; Department of Biotechnology and Bioinformatics, School of Life Sciences, University of Hyderabad, Hyderabad, Telangana, India.
Naz S; Centre for Liver Research and Diagnostics, Central Laboratory for Stem Cell Research and Translational Medicine, Deccan College of Medical Sciences, Kanchanbagh, Hyderabad, Telangana, India.
Huang W; Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America.
Khumukcham SS; Department of Biochemistry, School of Life Sciences, University of Hyderabad, Hyderabad, Telangana, India.
Khan RA; Department of Biotechnology and Bioinformatics, School of Life Sciences, University of Hyderabad, Hyderabad, Telangana, India.
Bhat SY; Department of Biotechnology and Bioinformatics, School of Life Sciences, University of Hyderabad, Hyderabad, Telangana, India.
Qureshi IA; Department of Biotechnology and Bioinformatics, School of Life Sciences, University of Hyderabad, Hyderabad, Telangana, India.
Manavathi B; Department of Biochemistry, School of Life Sciences, University of Hyderabad, Hyderabad, Telangana, India.
Khan AA; Centre for Liver Research and Diagnostics, Central Laboratory for Stem Cell Research and Translational Medicine, Deccan College of Medical Sciences, Kanchanbagh, Hyderabad, Telangana, India.
August A; Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America.
Hasnain SE; JH-Institute of Molecular Medicine, Jamia Hamdard University, Hamdard Nagar, New Delhi, India.; Molecular Infection and Functional Biology Laboratory, Kusuma School of Biological Sciences, Indian Institute of Technology, New Delhi, India.; Dr Reddy's Institute of Life Sciences, University of Hyderabad Campus, Hyderabad, Telangana, India.
Khan N; Department of Biotechnology and Bioinformatics, School of Life Sciences, University of Hyderabad, Hyderabad, Telangana, India.
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Źródło:
PLoS biology [PLoS Biol] 2018 Apr 05; Vol. 16 (4), pp. e2005317. Date of Electronic Publication: 2018 Apr 05 (Print Publication: 2018).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Protein Biosynthesis*
Amino Acids/*deficiency
Autophagy/*immunology
Colitis/*immunology
Interleukin-1beta/*immunology
Protein Serine-Threonine Kinases/*genetics
Adaptation, Physiological ; Animals ; Autophagy/drug effects ; Cells, Cultured ; Colitis/chemically induced ; Colitis/drug therapy ; Colitis/genetics ; Gene Expression Regulation ; Inflammasomes/genetics ; Inflammasomes/immunology ; Interleukin-1beta/genetics ; Lipopolysaccharides/pharmacology ; Macrophages/drug effects ; Macrophages/immunology ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Piperidines/pharmacology ; Protein Serine-Threonine Kinases/antagonists & inhibitors ; Protein Serine-Threonine Kinases/immunology ; Protein Synthesis Inhibitors/pharmacology ; Quinazolinones/pharmacology ; RNA, Messenger/genetics ; RNA, Messenger/immunology ; RNA, Small Interfering/genetics ; RNA, Small Interfering/immunology ; RNA-Binding Proteins/genetics ; RNA-Binding Proteins/immunology ; Reactive Oxygen Species/immunology ; Reactive Oxygen Species/metabolism ; Sodium Dodecyl Sulfate/administration & dosage ; Starvation/genetics ; Starvation/immunology ; Stress, Physiological ; T-Cell Intracellular Antigen-1/genetics ; T-Cell Intracellular Antigen-1/immunology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Microplate-Based Nonradioactive Protein Synthesis Assay: Application to TRAIL Sensitization by Protein Synthesis Inhibitors.
Autorzy:
Henrich CJ; Molecular Targets Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland, 21702, United States of America.; Basic Science Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, 21702, United States of America.
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Źródło:
PloS one [PLoS One] 2016 Oct 21; Vol. 11 (10), pp. e0165192. Date of Electronic Publication: 2016 Oct 21 (Print Publication: 2016).
Typ publikacji:
Journal Article; Validation Study
MeSH Terms:
Protein Biosynthesis/*drug effects
Protein Synthesis Inhibitors/*pharmacology
TNF-Related Apoptosis-Inducing Ligand/*metabolism
Cell Line, Tumor ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Protein Synthesis Inhibitors Did Not Interfere with Long-Term Depression Induced either Electrically in Juvenile Rats or Chemically in Middle-Aged Rats.
Autorzy:
Abbas AK; Institute of Neuroscience and Physiology, University of Gothenburg, Box 432, SE-40530, Gothenburg, Sweden.
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Źródło:
PloS one [PLoS One] 2016 Aug 12; Vol. 11 (8), pp. e0161270. Date of Electronic Publication: 2016 Aug 12 (Print Publication: 2016).
Typ publikacji:
Journal Article
MeSH Terms:
Electric Stimulation*
Hippocampus/*drug effects
Long-Term Potentiation/*drug effects
Long-Term Synaptic Depression/*drug effects
Protein Biosynthesis/*drug effects
Protein Synthesis Inhibitors/*pharmacology
Animals ; Animals, Newborn ; Anisomycin/pharmacology ; Cycloheximide/pharmacology ; Electrophysiology ; Hippocampus/metabolism ; Male ; Neuronal Plasticity/drug effects ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Detection of Burkholderia pseudomallei toxin-mediated inhibition of protein synthesis using a Caenorhabditis elegans ugt-29 biosensor.
Autorzy:
Wong RR; School of Biosciences and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 UKM Bangi Selangor, Malaysia.
Kong C; School of Biosciences and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 UKM Bangi Selangor, Malaysia.
Lee SH; School of Biosciences and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 UKM Bangi Selangor, Malaysia.
Nathan S; School of Biosciences and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 UKM Bangi Selangor, Malaysia.; Malaysia Genome Institute, Jalan Bangi, 43000 Kajang, Selangor, Malaysia.
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Źródło:
Scientific reports [Sci Rep] 2016 Jun 07; Vol. 6, pp. 27475. Date of Electronic Publication: 2016 Jun 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Biosensing Techniques*
Bacterial Toxins/*toxicity
Burkholderia pseudomallei/*pathogenicity
Caenorhabditis elegans/*metabolism
Protein Biosynthesis/*drug effects
Protein Synthesis Inhibitors/*toxicity
Animals
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Signal peptide-binding drug as a selective inhibitor of co-translational protein translocation.
Autorzy:
Vermeire K; KU Leuven - University of Leuven, Department of Microbiology and Immunology, Virology and Chemotherapy, Rega Institute for Medical Research, Leuven, Belgium; Institute of Biology, CSCM, University of Lübeck, Lübeck, Germany; MRC-Laboratory for Molecular Cell Biology, University College London, London, United Kingdom.
Bell TW; Department of Chemistry, University of Nevada, Reno, Nevada, United States of America.
Van Puyenbroeck V; KU Leuven - University of Leuven, Department of Microbiology and Immunology, Virology and Chemotherapy, Rega Institute for Medical Research, Leuven, Belgium.
Giraut A; KU Leuven - University of Leuven, Department of Microbiology and Immunology, Virology and Chemotherapy, Rega Institute for Medical Research, Leuven, Belgium.
Noppen S; KU Leuven - University of Leuven, Department of Microbiology and Immunology, Virology and Chemotherapy, Rega Institute for Medical Research, Leuven, Belgium.
Liekens S; KU Leuven - University of Leuven, Department of Microbiology and Immunology, Virology and Chemotherapy, Rega Institute for Medical Research, Leuven, Belgium.
Schols D; KU Leuven - University of Leuven, Department of Microbiology and Immunology, Virology and Chemotherapy, Rega Institute for Medical Research, Leuven, Belgium.
Hartmann E; Institute of Biology, CSCM, University of Lübeck, Lübeck, Germany.
Kalies KU; Institute of Biology, CSCM, University of Lübeck, Lübeck, Germany.
Marsh M; MRC-Laboratory for Molecular Cell Biology, University College London, London, United Kingdom.
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Źródło:
PLoS biology [PLoS Biol] 2014 Dec 02; Vol. 12 (12), pp. e1002011. Date of Electronic Publication: 2014 Dec 02 (Print Publication: 2014).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Protein Sorting Signals*
Protein Biosynthesis/*drug effects
Protein Synthesis Inhibitors/*pharmacology
Amino Acid Sequence ; CD4 Antigens/chemistry ; CD4 Antigens/metabolism ; Down-Regulation/drug effects ; Humans ; Hydrophobic and Hydrophilic Interactions ; Molecular Sequence Data ; Protein Conformation ; Protein Transport/drug effects ; Sulfonamides/chemistry ; Sulfonamides/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Selective sensitivity of early postmitotic retinal cells to apoptosis induced by inhibition of protein synthesis.
Autorzy:
Rehen SK; Instituto de Biofisica Carlos Chagas Filho, UFRJ, Centro de Ciencias daSaude, Rio de Janeiro, Brasil.
Neves DD
Fragel-Madeira L
Britto LR
Linden R
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Źródło:
The European journal of neuroscience [Eur J Neurosci] 1999 Dec; Vol. 11 (12), pp. 4349-56.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Apoptosis*
Mitosis*
Protein Biosynthesis*
Protein Synthesis Inhibitors/*metabolism
Retina/*cytology
Retina/*metabolism
Animals ; Anisomycin/pharmacology ; Bromodeoxyuridine ; Calbindin 2 ; Calbindins ; Cell Differentiation ; Cell Division ; Cells, Cultured ; Immunohistochemistry ; Proliferating Cell Nuclear Antigen/metabolism ; Protein Synthesis Inhibitors/pharmacology ; Rats ; Retina/drug effects ; Rhodopsin/metabolism ; S100 Calcium Binding Protein G/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Arabidopsis thaliana mitochondrial EF-G1 functions in two different translation steps.
Autorzy:
Suematsu T; Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, and Department of Applied Life Sciences, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji-shi, Tokyo 192-0392, Japan.
Watanabe O
Kita K
Yokobori S
Watanabe Y
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Źródło:
Journal of biochemistry [J Biochem] 2014 Feb; Vol. 155 (2), pp. 107-14. Date of Electronic Publication: 2013 Nov 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Protein Biosynthesis*
Arabidopsis/*metabolism
Mitochondria/*metabolism
Peptide Elongation Factor G/*physiology
Arabidopsis/classification ; Arabidopsis/genetics ; Evolution, Molecular ; Fusidic Acid/pharmacology ; GTP Phosphohydrolases/drug effects ; Humans ; Phylogeny ; Protein Synthesis Inhibitors/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Protein synthesis dependence of growth cone collapse induced by different Nogo-A-domains.
Autorzy:
Manns R; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom.
Schmandke A; Brain Research Institute, University of Zurich and Department of Health Sciences and Technology, Swiss Federal Institute of Technology, Zurich, Switzerland.
Schmandke A; Brain Research Institute, University of Zurich and Department of Health Sciences and Technology, Swiss Federal Institute of Technology, Zurich, Switzerland.
Jareonsettasin P; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom.
Cook G; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom.
Schwab ME; Brain Research Institute, University of Zurich and Department of Health Sciences and Technology, Swiss Federal Institute of Technology, Zurich, Switzerland.
Holt C; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom.
Keynes R; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom.
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Źródło:
PloS one [PLoS One] 2014 Jan 29; Vol. 9 (1), pp. e86820. Date of Electronic Publication: 2014 Jan 29 (Print Publication: 2014).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Ganglia, Spinal/*metabolism
Growth Cones/*metabolism
Myelin Proteins/*genetics
Myelin Proteins/*pharmacology
Protein Biosynthesis/*drug effects
Animals ; Anisomycin/pharmacology ; Chick Embryo ; Ganglia, Spinal/drug effects ; Ganglia, Spinal/pathology ; Gene Expression Regulation, Developmental ; Growth Cones/drug effects ; Growth Cones/pathology ; Laminin ; Leupeptins/pharmacology ; Myelin Proteins/metabolism ; Nogo Proteins ; Polylysine ; Proteasome Endopeptidase Complex/metabolism ; Proteasome Inhibitors/pharmacology ; Protein Structure, Tertiary ; Protein Synthesis Inhibitors/pharmacology ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Recombinant Proteins/pharmacology ; Signal Transduction ; Tissue Culture Techniques ; rhoA GTP-Binding Protein/genetics ; rhoA GTP-Binding Protein/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Long-lasting LTP requires neither repeated trains for its induction nor protein synthesis for its development.
Autorzy:
Villers A; Department of Neurosciences, University of Mons, Mons, Belgium.
Godaux E
Ris L
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Źródło:
PloS one [PLoS One] 2012; Vol. 7 (7), pp. e40823. Date of Electronic Publication: 2012 Jul 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Long-Term Potentiation/*physiology
Memory/*physiology
Protein Biosynthesis/*physiology
Animals ; Calcium-Calmodulin-Dependent Protein Kinase Type 2/metabolism ; Electric Stimulation ; Hippocampus/drug effects ; Hippocampus/physiology ; Mice ; N-Methylaspartate/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Phosphorylation/drug effects ; Protein Biosynthesis/drug effects ; Protein Synthesis Inhibitors/pharmacology ; Receptors, AMPA/metabolism ; Receptors, N-Methyl-D-Aspartate/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Fine-tuning translation kinetics selection as the driving force of codon usage bias in the hepatitis A virus capsid.
Autorzy:
Aragonès L; Enteric Virus Laboratory, Department of Microbiology and Institute of Nutrition and Food Safety, University of Barcelona, Barcelona, Spain.
Guix S
Ribes E
Bosch A
Pintó RM
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Źródło:
PLoS pathogens [PLoS Pathog] 2010 Mar 05; Vol. 6 (3), pp. e1000797. Date of Electronic Publication: 2010 Mar 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Capsid Proteins/*genetics
Codon/*genetics
Hepatitis A virus/*genetics
Protein Biosynthesis/*genetics
RNA, Transfer/*genetics
Anticodon/genetics ; Capsid Proteins/chemistry ; Dactinomycin/pharmacology ; Eukaryotic Initiation Factor-4G/genetics ; Gene Expression Regulation, Viral ; HSP90 Heat-Shock Proteins/physiology ; Hepatitis A virus/growth & development ; Protein Folding ; Protein Synthesis Inhibitors/pharmacology ; Virus Replication/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Protein synthesis and degradation are required for the incorporation of modified information into the pre-existing object-location memory.
Autorzy:
Choi JH; National Creative Research Initiative Center for Memory, Department of Biological Sciences, College of Natural Sciences, Seoul National University, 151-742 Seoul, Korea.
Kim JE
Kaang BK
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Źródło:
Molecular brain [Mol Brain] 2010 Jan 08; Vol. 3, pp. 1. Date of Electronic Publication: 2010 Jan 08.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Memory*/drug effects
Memory*/physiology
Protein Biosynthesis*/drug effects
Protein Biosynthesis*/physiology
Anisomycin/*pharmacology
Protein Synthesis Inhibitors/*pharmacology
Proteins/*metabolism
Animals ; Behavior, Animal/drug effects ; Male ; Mice ; Mice, Inbred C57BL ; Neuropsychological Tests
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Cardiac glycosides induce cell death in human cells by inhibiting general protein synthesis.
Autorzy:
Perne A; Department of Medical and Chemical Laboratory Diagnostics, Medical University of Vienna, Vienna, Austria.
Muellner MK
Steinrueck M
Craig-Mueller N
Mayerhofer J
Schwarzinger I
Sloane M
Uras IZ
Hoermann G
Nijman SM
Mayerhofer M
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Źródło:
PloS one [PLoS One] 2009 Dec 16; Vol. 4 (12), pp. e8292. Date of Electronic Publication: 2009 Dec 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cardiac Glycosides/*pharmacology
Protein Biosynthesis/*drug effects
Protein Synthesis Inhibitors/*pharmacology
Animals ; Cell Death/drug effects ; Cell Line ; Cell Proliferation/drug effects ; Digitoxin/pharmacology ; Dose-Response Relationship, Drug ; Humans ; Janus Kinase 2/antagonists & inhibitors ; Mice ; Mutant Proteins/metabolism ; Sodium-Potassium-Exchanging ATPase
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Protein synthesis and neurotrophin-dependent structural plasticity of single dendritic spines.
Autorzy:
Tanaka J; Laboratory of Structural Physiology, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, University of Tokyo, Tokyo 113-0033, Japan.
Horiike Y
Matsuzaki M
Miyazaki T
Ellis-Davies GC
Kasai H
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Źródło:
Science (New York, N.Y.) [Science] 2008 Mar 21; Vol. 319 (5870), pp. 1683-7. Date of Electronic Publication: 2008 Feb 28.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Neuronal Plasticity*
Protein Biosynthesis*
Brain-Derived Neurotrophic Factor/*metabolism
Dendritic Spines/*physiology
Dendritic Spines/*ultrastructure
Synapses/*physiology
Action Potentials ; Animals ; Brain-Derived Neurotrophic Factor/pharmacology ; Cells, Cultured ; Glutamic Acid/metabolism ; Patch-Clamp Techniques ; Protein Synthesis Inhibitors/pharmacology ; Pyramidal Cells/physiology ; Pyramidal Cells/ultrastructure ; Rats ; Rats, Sprague-Dawley ; Receptor, trkB/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The antibiotic viomycin traps the ribosome in an intermediate state of translocation.
Autorzy:
Ermolenko DN; Department of Molecular, Cell and Developmental Biology and Center for Molecular Biology of RNA, University of California, Santa Cruz, California 95064, USA.
Spiegel PC
Majumdar ZK
Hickerson RP
Clegg RM
Noller HF
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Źródło:
Nature structural & molecular biology [Nat Struct Mol Biol] 2007 Jun; Vol. 14 (6), pp. 493-7. Date of Electronic Publication: 2007 May 21.
Typ publikacji:
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Models, Molecular*
Protein Biosynthesis/*drug effects
Protein Synthesis Inhibitors/*pharmacology
RNA, Messenger/*metabolism
RNA, Transfer/*metabolism
Ribosome Subunits/*metabolism
Viomycin/*pharmacology
Fluorescence Resonance Energy Transfer ; Peptide Elongation Factor G/metabolism ; Protein Biosynthesis/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 53

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