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Wyszukujesz frazę ""Protein-Arginine Deiminases"" wg kryterium: Temat


Tytuł :
Current knowledge into the role of the peptidylarginine deiminase (PAD) enzyme family in cardiovascular disease.
Autorzy :
Al-U'datt DGF; Department of Physiology and Biochemistry, Faculty of Medicine, Jordan University of Science and Technology, Irbid, 22110, Jordan. Electronic address: .
Allen BG; Department of Pharmacology and Physiology, Université de Montréal, Montreal, Quebec, Canada; Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada; Department of Medicine, Université de Montréal, Montreal, Quebec, Canada; Department of Biochemistry and Molecular Medicine, Université de Montréal, Montreal, Quebec, Canada.
Hiram R; Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada.
Alrabadi N; Department of Pharmacology, Faculty of Medicine, Jordan University of Science and Technology, Irbid, 22110, Jordan.
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Źródło :
European journal of pharmacology [Eur J Pharmacol] 2021 Jan 15; Vol. 891, pp. 173765. Date of Electronic Publication: 2020 Nov 26.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Cardiovascular Diseases/*enzymology
Cardiovascular System/*enzymology
Extracellular Matrix/*enzymology
Protein-Arginine Deiminases/*metabolism
Animals ; Atrial Remodeling ; Cardiovascular Diseases/drug therapy ; Cardiovascular Diseases/physiopathology ; Cardiovascular System/drug effects ; Cardiovascular System/physiopathology ; Citrullination ; Deamination ; Enzyme Inhibitors/therapeutic use ; Humans ; Protein-Arginine Deiminases/antagonists & inhibitors ; Vascular Remodeling ; Ventricular Remodeling
Czasopismo naukowe
Tytuł :
Deimination, Intermediate Filaments and Associated Proteins.
Autorzy :
Briot J; UDEAR, Institut National de la Santé Et de la Recherche Médicale, Université Toulouse III Paul Sabatier, Université Fédérale de Toulouse Midi-Pyrénées, U1056, 31059 Toulouse, France.
Simon M; UDEAR, Institut National de la Santé Et de la Recherche Médicale, Université Toulouse III Paul Sabatier, Université Fédérale de Toulouse Midi-Pyrénées, U1056, 31059 Toulouse, France.
Méchin MC; UDEAR, Institut National de la Santé Et de la Recherche Médicale, Université Toulouse III Paul Sabatier, Université Fédérale de Toulouse Midi-Pyrénées, U1056, 31059 Toulouse, France.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Nov 19; Vol. 21 (22). Date of Electronic Publication: 2020 Nov 19.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Protein Processing, Post-Translational*
Arthritis, Rheumatoid/*enzymology
Intermediate Filament Proteins/*metabolism
Intermediate Filaments/*enzymology
Multiple Sclerosis/*enzymology
Neoplasms/*enzymology
Neurodegenerative Diseases/*enzymology
Protein-Arginine Deiminases/*metabolism
Arthritis, Rheumatoid/genetics ; Arthritis, Rheumatoid/immunology ; Arthritis, Rheumatoid/pathology ; Cell Differentiation ; Citrullination ; Epithelial Cells/enzymology ; Epithelial Cells/pathology ; Humans ; Intermediate Filament Proteins/chemistry ; Intermediate Filament Proteins/genetics ; Intermediate Filaments/ultrastructure ; Mesenchymal Stem Cells/enzymology ; Mesenchymal Stem Cells/pathology ; Multiple Sclerosis/genetics ; Multiple Sclerosis/immunology ; Multiple Sclerosis/pathology ; Neoplasms/genetics ; Neoplasms/immunology ; Neoplasms/pathology ; Neurodegenerative Diseases/genetics ; Neurodegenerative Diseases/immunology ; Neurodegenerative Diseases/pathology ; Neurons/enzymology ; Neurons/pathology ; Protein Multimerization ; Protein-Arginine Deiminases/chemistry ; Protein-Arginine Deiminases/genetics ; Proteolysis ; Solubility
Czasopismo naukowe
Tytuł :
Peptidylarginine Deiminase 4 Promotes the Renal Infiltration of Neutrophils and Exacerbates the TLR7 Agonist-Induced Lupus Mice.
Autorzy :
Hanata N; Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Shoda H; Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Hatano H; Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Nagafuchi Y; Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Komai T; Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Okamura T; Department of Functional Genomics and Immunological Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Suzuki A; Laboratory for Autoimmune Diseases, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
Gunarta IK; Division of Molecular Cell Signaling, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.
Yoshioka K; Division of Molecular Cell Signaling, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.
Yamamoto K; Laboratory for Autoimmune Diseases, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
Fujio K; Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
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Źródło :
Frontiers in immunology [Front Immunol] 2020 Jun 23; Vol. 11, pp. 1095. Date of Electronic Publication: 2020 Jun 23 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Kidney/*immunology
Lupus Nephritis/*etiology
Membrane Glycoproteins/*agonists
Neutrophil Infiltration/*physiology
Protein-Arginine Deiminases/*metabolism
Toll-Like Receptor 7/*agonists
Adaptor Proteins, Signal Transducing/genetics ; Adaptor Proteins, Signal Transducing/metabolism ; Adoptive Transfer ; Animals ; Disease Models, Animal ; Female ; Gene Expression Regulation ; Kidney/pathology ; Lupus Nephritis/enzymology ; Lupus Nephritis/immunology ; MAP Kinase Signaling System ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Neutrophil Infiltration/genetics ; Neutrophils/enzymology ; Neutrophils/immunology ; Neutrophils/pathology ; Protein-Arginine Deiminases/deficiency ; Protein-Arginine Deiminases/genetics ; RNA-Seq ; p38 Mitogen-Activated Protein Kinases/metabolism
Czasopismo naukowe
Tytuł :
A modified arginine-depleting enzyme NEI-01 inhibits growth of pancreatic cancer cells.
Autorzy :
Chow JPH; New Epsilon Innovation Limited, Hong Kong, China.
Cai Y; New Epsilon Innovation Limited, Hong Kong, China.
Chow DTL; New Epsilon Innovation Limited, Hong Kong, China.
Chung SHK; New Epsilon Innovation Limited, Hong Kong, China.
Chau KC; New Epsilon Innovation Limited, Hong Kong, China.
Ng KY; New Epsilon Innovation Limited, Hong Kong, China.
Leung OM; New Epsilon Innovation Limited, Hong Kong, China.
Wong RMH; New Epsilon Innovation Limited, Hong Kong, China.
Law AWL; New Epsilon Innovation Limited, Hong Kong, China.
Leung YO; New Epsilon Innovation Limited, Hong Kong, China.
Kwok SY; New Epsilon Innovation Limited, Hong Kong, China.
Leung YC; State Key Laboratory of Chemical Biology and Drug Discovery, Department of Applied Biology and Chemical Technology and Lo Ka Chung Research Centre for Natural Anti-Cancer Drug Development, The Hong Kong Polytechnic University, Hong Kong, China.
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Źródło :
PloS one [PLoS One] 2020 Apr 30; Vol. 15 (4), pp. e0231633. Date of Electronic Publication: 2020 Apr 30 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*therapeutic use
Arginine/*metabolism
Carcinoma/*drug therapy
Pancreatic Neoplasms/*drug therapy
Protein-Arginine Deiminases/*therapeutic use
Animals ; Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/metabolism ; Arginine/blood ; Arginine/deficiency ; Argininosuccinate Synthase/metabolism ; Cell Line, Tumor ; Female ; Humans ; Injections, Intraperitoneal ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Protein Binding ; Protein-Arginine Deiminases/administration & dosage ; Protein-Arginine Deiminases/metabolism ; Rats ; Serum Albumin/metabolism
Czasopismo naukowe
Tytuł :
Putative Roles for Peptidylarginine Deiminases in COVID-19.
Autorzy :
Arisan ED; Gebze Technical University, Institute of Biotechnology, Gebze, 41400 Kocaeli, Turkey.
Uysal-Onganer P; Cancer Research Group, School of Life Sciences, University of Westminster, London W1W 6UW, UK.
Lange S; Tissue Architecture and Regeneration Research Group, School of Life Sciences, University of Westminster, London W1W 6UW, UK.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Jun 30; Vol. 21 (13). Date of Electronic Publication: 2020 Jun 30.
Typ publikacji :
Journal Article
MeSH Terms :
Coronavirus Infections/*pathology
Pneumonia, Viral/*pathology
Protein-Arginine Deiminases/*metabolism
Betacoronavirus/isolation & purification ; COVID-19 ; Case-Control Studies ; Cell Line ; Coronavirus Infections/metabolism ; Cytokines/metabolism ; Databases, Factual ; Epithelial Cells/cytology ; Epithelial Cells/metabolism ; Epithelial Cells/virology ; Extracellular Vesicles/metabolism ; Humans ; Isoenzymes/genetics ; Isoenzymes/metabolism ; Lung/enzymology ; Lung/pathology ; Lung/virology ; Pandemics ; Pneumonia, Viral/metabolism ; Protein Interaction Maps ; Protein-Arginine Deiminases/genetics ; RNA, Messenger/metabolism ; SARS-CoV-2
Czasopismo naukowe
Tytuł :
Peptidyl arginine deiminase 4 and its potential role in Alzheimer's disease.
Autorzy :
Wang LL; Department of Neurology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 201100, China.
Song YP; Department of Neurology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 201100, China.
Mi JH; Department of Neurology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, 201100, China.
Ding ML; Department of Clinical Laboratory, Shanghai East Hospital, School of Medicine, Tongji University, 200120, China. Electronic address: .
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Źródło :
Medical hypotheses [Med Hypotheses] 2021 Jan; Vol. 146, pp. 110466. Date of Electronic Publication: 2020 Dec 22.
Typ publikacji :
Journal Article
MeSH Terms :
Alzheimer Disease*
Citrullination*
Humans ; Hydrolases/genetics ; Hydrolases/metabolism ; Protein-Arginine Deiminase Type 4 ; Protein-Arginine Deiminases/genetics ; Protein-Arginine Deiminases/metabolism
Czasopismo naukowe
Tytuł :
PADs in cancer: Current and future.
Autorzy :
Zhang Y; Department of Pathology and Pathophysiology, School of Medicine, Southeast University, Nanjing, Jiangsu 210009, PR China.
Yang Y; Department of Pathology and Pathophysiology, School of Medicine, Southeast University, Nanjing, Jiangsu 210009, PR China.
Hu X; Department of Pathology and Pathophysiology, School of Medicine, Southeast University, Nanjing, Jiangsu 210009, PR China.
Wang Z; Department of Pathology and Pathophysiology, School of Medicine, Southeast University, Nanjing, Jiangsu 210009, PR China.
Li L; Department of Pathology and Pathophysiology, School of Medicine, Southeast University, Nanjing, Jiangsu 210009, PR China.
Chen P; Department of Pathology and Pathophysiology, School of Medicine, Southeast University, Nanjing, Jiangsu 210009, PR China. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Reviews on cancer [Biochim Biophys Acta Rev Cancer] 2021 Jan; Vol. 1875 (1), pp. 188492. Date of Electronic Publication: 2020 Dec 13.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Citrullination/*genetics
Epithelial-Mesenchymal Transition/*genetics
Neoplasms/*genetics
Protein-Arginine Deiminases/*genetics
Citrulline/genetics ; Citrulline/metabolism ; Extracellular Traps/genetics ; Humans ; Neoplasms/pathology ; Signal Transduction/genetics
Czasopismo naukowe
Tytuł :
Deimination and Peptidylarginine Deiminases in Skin Physiology and Diseases.
Autorzy :
Méchin MC; UDEAR, Institut National de la Santé Et de la Recherche Médicale, Université Paul Sabatier, Université de Toulouse Midi-Pyrénées, U1056, Toulouse 31059, France.
Takahara H; University of Ibaraki, School of Agriculture, Ibaraki 300-0393, Japan.
Simon M; UDEAR, Institut National de la Santé Et de la Recherche Médicale, Université Paul Sabatier, Université de Toulouse Midi-Pyrénées, U1056, Toulouse 31059, France.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Jan 15; Vol. 21 (2). Date of Electronic Publication: 2020 Jan 15.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Gene Expression Regulation*
Protein Processing, Post-Translational*
Protein-Arginine Deiminases/*genetics
Skin Diseases/*genetics
Skin Physiological Phenomena/*genetics
Citrullination ; Homeostasis/genetics ; Humans ; Isoenzymes/genetics ; Isoenzymes/metabolism ; Keratinocytes/metabolism ; Protein-Arginine Deiminases/metabolism ; Skin/metabolism ; Skin/pathology ; Skin Diseases/metabolism
Czasopismo naukowe
Tytuł :
An interplay of structure and intrinsic disorder in the functionality of peptidylarginine deiminases, a family of key autoimmunity-related enzymes.
Autorzy :
Alghamdi M; Biological Sciences Department, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah, 21589, Saudi Arabia.; Laboratory Department, University Medical Services Center, King Abdulaziz University, P.O. Box 80200, Jeddah, 21589, Saudi Arabia.
Al Ghamdi KA; Biological Sciences Department, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah, 21589, Saudi Arabia.
Khan RH; Interdisciplinary Biotechnology Unit, Aligarh Muslim University, Aligarh, UP, India.
Uversky VN; Biological Sciences Department, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah, 21589, Saudi Arabia. .; Protein Research Group, Institute for Biological Instrumentation of the Russian Academy of Sciences, 7 Institutskaya Str., 142290, Pushchino, Moscow region, Russia. .; Department of Molecular Medicine and USF Health Byrd Alzheimer's Research Institute, Morsani College of Medicine, University of South Florida, Tampa, FL, USA. .
Redwan EM; Biological Sciences Department, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah, 21589, Saudi Arabia. .; Therapeutic and Protective Proteins Laboratory, Protein Research Department, Genetic Engineering and Biotechnology Research Institute, City for Scientific Research and Technology Applications, New Borg EL-Arab, Alexandria, 21934, Egypt. .
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Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2019 Dec; Vol. 76 (23), pp. 4635-4662. Date of Electronic Publication: 2019 Jul 24.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Autoimmunity*
Protein-Arginine Deiminases/*metabolism
Animals ; Calcium/chemistry ; Calcium/metabolism ; Cell Death ; Citrulline/metabolism ; Enzyme Inhibitors/chemistry ; Enzyme Inhibitors/metabolism ; Humans ; Isoenzymes/antagonists & inhibitors ; Isoenzymes/chemistry ; Isoenzymes/metabolism ; Protein-Arginine Deiminases/antagonists & inhibitors ; Protein-Arginine Deiminases/genetics ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł :
Peptidylarginine Deiminase Inhibition Prevents Diabetes Development in NOD Mice.
Autorzy :
Sodré FMC; Laboratory for Clinical and Experimental Endocrinology, KU Leuven, Leuven, Belgium.
Bissenova S; Laboratory for Clinical and Experimental Endocrinology, KU Leuven, Leuven, Belgium.
Bruggeman Y; Laboratory for Clinical and Experimental Endocrinology, KU Leuven, Leuven, Belgium.
Tilvawala R; Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA.; Department of Molecular Biosciences, The University of Kansas, Lawrence, KS.
Cook DP; Laboratory for Clinical and Experimental Endocrinology, KU Leuven, Leuven, Belgium.
Berthault C; Université de Paris, Institut Cochin, CNRS, INSERM, Paris, France.
Mondal S; Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA.
Callebaut A; Laboratory for Clinical and Experimental Endocrinology, KU Leuven, Leuven, Belgium.
You S; Université de Paris, Institut Cochin, CNRS, INSERM, Paris, France.
Scharfmann R; Université de Paris, Institut Cochin, CNRS, INSERM, Paris, France.
Mallone R; Université de Paris, Institut Cochin, CNRS, INSERM, Paris, France.; Assistance Publique Hôpitaux de Paris, Hôpitaux Universitaires de Paris Centre-Université de Paris, Cochin Hospital, Service de Diabétologie et Immunologie Clinique, Paris, France.
Thompson PR; Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA.
Mathieu C; Laboratory for Clinical and Experimental Endocrinology, KU Leuven, Leuven, Belgium.
Buitinga M; Laboratory for Clinical and Experimental Endocrinology, KU Leuven, Leuven, Belgium.
Overbergh L; Laboratory for Clinical and Experimental Endocrinology, KU Leuven, Leuven, Belgium .
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Źródło :
Diabetes [Diabetes] 2021 Feb; Vol. 70 (2), pp. 516-528. Date of Electronic Publication: 2020 Nov 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Diabetes Mellitus, Type 1/*metabolism
Insulin/*metabolism
Ornithine/*analogs & derivatives
Pancreas/*drug effects
Protein-Arginine Deiminases/*antagonists & inhibitors
Animals ; Cytokines/metabolism ; Diabetes Mellitus, Type 1/prevention & control ; Extracellular Traps/drug effects ; Extracellular Traps/metabolism ; Mice ; Mice, Inbred NOD ; Ornithine/pharmacology ; Pancreas/metabolism ; T-Lymphocytes, Regulatory/drug effects ; T-Lymphocytes, Regulatory/metabolism
Czasopismo naukowe
Tytuł :
The Proteome and Citrullinome of Hippoglossus hippoglossus Extracellular Vesicles-Novel Insights into Roles of the Serum Secretome in Immune, Gene Regulatory and Metabolic Pathways.
Autorzy :
Magnadóttir B; Institute for Experimental Pathology at Keldur, University of Iceland, Keldnavegur 3, 112 Reykjavik, Iceland.
Kraev I; Electron Microscopy Suite, Faculty of Science, Technology, Engineering and Mathematics, Open University, Milton Keynes MK7 6AA, UK.
Dodds AW; MRC Immunochemistry Unit, Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.
Lange S; Tissue Architecture and Regeneration Research Group, Department of Biomedical Sciences, University of Westminster, London W1W 6UW, UK.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jan 16; Vol. 22 (2). Date of Electronic Publication: 2021 Jan 16.
Typ publikacji :
Journal Article
MeSH Terms :
Citrullination*
Extracellular Vesicles/*metabolism
Fish Proteins/*metabolism
Proteome/*metabolism
Animals ; Complement System Proteins/metabolism ; Extracellular Vesicles/ultrastructure ; Fish Proteins/blood ; Flounder ; Protein Interaction Maps ; Protein-Arginine Deiminases/metabolism
Czasopismo naukowe
Tytuł :
An Overview of the Intrinsic Role of Citrullination in Autoimmune Disorders.
Autorzy :
Alghamdi M; Biological Sciences Department, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah 21589, Saudi Arabia.; Laboratory Department, University Medical Services Center, King Abdulaziz University, P.O. Box 80200, Jeddah 21589, Saudi Arabia.
Alasmari D; Biological Sciences Department, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah 21589, Saudi Arabia.
Assiri A; Biological Sciences Department, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah 21589, Saudi Arabia.
Mattar E; Biological Sciences Department, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah 21589, Saudi Arabia.
Aljaddawi AA; Biological Sciences Department, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah 21589, Saudi Arabia.
Alattas SG; Biological Sciences Department, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah 21589, Saudi Arabia.
Redwan EM; Biological Sciences Department, Faculty of Science, King Abdulaziz University, P.O. Box 80203, Jeddah 21589, Saudi Arabia.; Therapeutic and Protective Proteins Laboratory, Protein Research Department, Genetic Engineering and Biotechnology Research Institute, City for Scientific Research and Technology Applications, New Borg EL-Arab, Alexandria 21934, Egypt.
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Źródło :
Journal of immunology research [J Immunol Res] 2019 Nov 25; Vol. 2019, pp. 7592851. Date of Electronic Publication: 2019 Nov 25 (Print Publication: 2019).
Typ publikacji :
Journal Article; Meta-Analysis; Review
MeSH Terms :
Disease Susceptibility*
Autoimmune Diseases/*etiology
Autoimmune Diseases/*metabolism
Citrulline/*metabolism
Protein-Arginine Deiminases/*metabolism
Autoimmune Diseases/diagnosis ; Autoimmunity ; Biomarkers ; Citrullination ; Genetic Predisposition to Disease ; Humans ; Protein-Arginine Deiminases/genetics ; Risk Factors
Czasopismo naukowe
Tytuł :
NETosis Is Required for S100A8/A9-Induced Granulopoiesis After Myocardial Infarction.
Autorzy :
Nagareddy PR; Division of Cardiac Surgery, Department of Surgery, Ohio State University Wexner Medical Center, Columbus (P.R.N., G.S., R.M.J., J.J., B.A.).
Sreejit G; Division of Cardiac Surgery, Department of Surgery, Ohio State University Wexner Medical Center, Columbus (P.R.N., G.S., R.M.J., J.J., B.A.).
Abo-Aly M; Division of Cardiovascular Medicine, Department of Medicine, University of Kentucky, Lexington (M.A.-A., L.C., A.A.-L.).
Jaggers RM; Division of Cardiac Surgery, Department of Surgery, Ohio State University Wexner Medical Center, Columbus (P.R.N., G.S., R.M.J., J.J., B.A.).
Chelvarajan L; Division of Cardiovascular Medicine, Department of Medicine, University of Kentucky, Lexington (M.A.-A., L.C., A.A.-L.).
Johnson J; Division of Cardiac Surgery, Department of Surgery, Ohio State University Wexner Medical Center, Columbus (P.R.N., G.S., R.M.J., J.J., B.A.).
Pernes G; Division of Immunometabolism, Baker Heart and Diabetes Institute, Melbourne, Australia (G.P., A.J.M.).
Athmanathan B; Division of Cardiac Surgery, Department of Surgery, Ohio State University Wexner Medical Center, Columbus (P.R.N., G.S., R.M.J., J.J., B.A.).
Abdel-Latif A; Division of Cardiovascular Medicine, Department of Medicine, University of Kentucky, Lexington (M.A.-A., L.C., A.A.-L.).
Murphy AJ; Division of Immunometabolism, Baker Heart and Diabetes Institute, Melbourne, Australia (G.P., A.J.M.).
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2020 Nov; Vol. 40 (11), pp. 2805-2807. Date of Electronic Publication: 2020 Sep 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Leukopoiesis*
Calgranulin A/*metabolism
Calgranulin B/*metabolism
Extracellular Traps/*metabolism
Myocardial Infarction/*metabolism
Neutrophils/*metabolism
Animals ; Calgranulin A/blood ; Calgranulin B/blood ; Case-Control Studies ; Disease Models, Animal ; Humans ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Myocardial Infarction/immunology ; Myocardial Infarction/pathology ; Neutrophils/immunology ; Neutrophils/pathology ; Non-ST Elevated Myocardial Infarction/blood ; Protein-Arginine Deiminases/deficiency ; Protein-Arginine Deiminases/genetics ; ST Elevation Myocardial Infarction/blood ; Signal Transduction ; Time Factors
Czasopismo naukowe
Tytuł :
Deiminated proteins in extracellular vesicles and plasma of nurse shark (Ginglymostoma cirratum) - Novel insights into shark immunity.
Autorzy :
Criscitiello MF; Comparative Immunogenetics Laboratory, Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, 77843, USA; Department of Microbial Pathogenesis and Immunology, College of Medicine, Texas A&M Health Science Center, Texas A&M University, College Station, TX, 77843, USA. Electronic address: .
Kraev I; School of Life, Health and Chemical Sciences, The Open University, Walton Hall, MK7 6AA, UK. Electronic address: .
Lange S; Tissue Architecture and Regeneration Research Group, School of Life Sciences, University of Westminster, London, W1W 6UW, UK. Electronic address: .
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Źródło :
Fish & shellfish immunology [Fish Shellfish Immunol] 2019 Sep; Vol. 92, pp. 249-255. Date of Electronic Publication: 2019 Jun 12.
Typ publikacji :
Journal Article
MeSH Terms :
Arginine/*metabolism
Citrullination/*immunology
Citrulline/*metabolism
Fish Proteins/*immunology
Protein-Arginine Deiminases/*immunology
Sharks/*immunology
Animals ; Citrulline/immunology ; Extracellular Vesicles/immunology ; Extracellular Vesicles/metabolism ; Fish Proteins/blood ; Fish Proteins/metabolism ; Protein-Arginine Deiminases/genetics ; Sharks/genetics
Czasopismo naukowe
Tytuł :
Biochemical characterization of peptidylarginine deiminase-like orthologs from thermotolerant Emericella dentata and Aspergillus nidulans.
Autorzy :
El-Sayed ASA; Enzymology and Fungal Biotechnology Lab (EFBL), Botany and Microbiology Department, Faculty of Science, Zagazig University, Zagazig, 44519, Egypt. Electronic address: .
Shindia AA; Enzymology and Fungal Biotechnology Lab (EFBL), Botany and Microbiology Department, Faculty of Science, Zagazig University, Zagazig, 44519, Egypt.
AbouZaid AA; Enzymology and Fungal Biotechnology Lab (EFBL), Botany and Microbiology Department, Faculty of Science, Zagazig University, Zagazig, 44519, Egypt.
Yassin AM; Enzymology and Fungal Biotechnology Lab (EFBL), Botany and Microbiology Department, Faculty of Science, Zagazig University, Zagazig, 44519, Egypt.
Ali GS; MREC, Department of Plant Pathology, University of Florida, Florida, 32703, USA.
Sitohy MZ; Biochemistry Department, Faculty of Agriculture, Zagazig University, Zagazig, Egypt.
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Źródło :
Enzyme and microbial technology [Enzyme Microb Technol] 2019 May; Vol. 124, pp. 41-53. Date of Electronic Publication: 2019 Feb 07.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Aspergillus nidulans/*enzymology
Emericella/*enzymology
Protein-Arginine Deiminases/*chemistry
Protein-Arginine Deiminases/*metabolism
Aspergillus fumigatus/enzymology ; Enzyme Stability ; Humans ; Hydrogen-Ion Concentration ; Kinetics ; Molecular Weight ; Peptides/chemistry ; Protein Conformation ; Protein-Arginine Deiminases/isolation & purification ; Temperature
Czasopismo naukowe
Tytuł :
Development of a highly sensitive fluorescence probe for peptidyl arginine deiminase (PAD) activity.
Autorzy :
Kunieda K; Graduate School of Pharmaceutical Science, Nagoya City University, 3-1 Tanabe-dori, Mizuho-ku, Nagoya, Aichi, Japan.
Kawaguchi M; Graduate School of Pharmaceutical Science, Nagoya City University, 3-1 Tanabe-dori, Mizuho-ku, Nagoya, Aichi, Japan.
Ieda N; Graduate School of Pharmaceutical Science, Nagoya City University, 3-1 Tanabe-dori, Mizuho-ku, Nagoya, Aichi, Japan.
Nakagawa H; Graduate School of Pharmaceutical Science, Nagoya City University, 3-1 Tanabe-dori, Mizuho-ku, Nagoya, Aichi, Japan. Electronic address: .
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Źródło :
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2019 Apr 01; Vol. 29 (7), pp. 923-928. Date of Electronic Publication: 2019 Jan 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Fluorescent Dyes/*chemical synthesis
Protein-Arginine Deiminases/*metabolism
Citrulline/chemistry ; Fluorescent Dyes/chemistry ; High-Throughput Screening Assays ; Molecular Structure ; Protein-Arginine Deiminases/antagonists & inhibitors ; Protein-Arginine Deiminases/chemistry
Czasopismo naukowe
Tytuł :
Structure, function, and inhibition of a genomic/clinical variant of Porphyromonas gingivalis peptidylarginine deiminase.
Autorzy :
Bereta G; Department of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, PL-30-387, Kraków, Poland.
Goulas T; Proteolysis Laboratory, Structural Biology Unit, Molecular Biology Institute of Barcelona, CSIC, Barcelona Science Park, Helix Building, c/Baldiri Reixac, 15-21, E-08028, Barcelona, Catalonia, Spain.
Madej M; Department of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, PL-30-387, Kraków, Poland.
Bielecka E; Malopolska Centre of Biotechnology, Jagiellonian University, Gronostajowa 7A, PL-30-387, Kraków, Poland.
Solà M; Structural MitoLab, Structural Biology Unit, Molecular Biology Institute of Barcelona, CSIC, Barcelona Science Park, Helix Building, c/Baldiri Reixac, 15-21, E-08028, Barcelona, Catalonia, Spain.
Potempa J; Department of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, PL-30-387, Kraków, Poland.; Department of Oral Immunology and Infectious Diseases, University of Louisville School of Dentistry, Louisville, Kentucky, 40202.
Xavier Gomis-Rüth F; Proteolysis Laboratory, Structural Biology Unit, Molecular Biology Institute of Barcelona, CSIC, Barcelona Science Park, Helix Building, c/Baldiri Reixac, 15-21, E-08028, Barcelona, Catalonia, Spain.
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Źródło :
Protein science : a publication of the Protein Society [Protein Sci] 2019 Mar; Vol. 28 (3), pp. 478-486. Date of Electronic Publication: 2019 Jan 30.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Enzyme Inhibitors/*pharmacology
Porphyromonas gingivalis/*enzymology
Porphyromonas gingivalis/*genetics
Protein-Arginine Deiminases/*antagonists & inhibitors
Protein-Arginine Deiminases/*genetics
Amino Acid Substitution ; Bacteroidaceae Infections/drug therapy ; Bacteroidaceae Infections/microbiology ; Crystallography, X-Ray ; Humans ; Models, Molecular ; Porphyromonas gingivalis/chemistry ; Protein Conformation ; Protein-Arginine Deiminases/chemistry ; Protein-Arginine Deiminases/metabolism
Czasopismo naukowe
Tytuł :
Development of Activity-Based Proteomic Probes for Protein Citrullination.
Autorzy :
Nemmara VV; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, LRB 826, 364 Plantation Street, Worcester, MA, 01605, USA.; Program in Chemical Biology, University of Massachusetts Medical School, LRB 826, 364 Plantation Street, Worcester, MA, 01605, USA.
Thompson PR; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, LRB 826, 364 Plantation Street, Worcester, MA, 01605, USA. .; Program in Chemical Biology, University of Massachusetts Medical School, LRB 826, 364 Plantation Street, Worcester, MA, 01605, USA. .
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Źródło :
Current topics in microbiology and immunology [Curr Top Microbiol Immunol] 2019; Vol. 420, pp. 233-251.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Citrullination*/drug effects
Citrulline/*metabolism
Protein-Arginine Deiminases/*analysis
Protein-Arginine Deiminases/*metabolism
Proteomics/*methods
Citrulline/chemistry ; Disease ; Humans ; Molecular Probe Techniques ; Protein-Arginine Deiminases/antagonists & inhibitors ; Protein-Arginine Deiminases/chemistry
Czasopismo naukowe
Tytuł :
Role of the RprY response regulator in P. gingivalis community development and virulence.
Autorzy :
Shen D; Department of Oral Immunology and Infectious Diseases, University of Louisville School of Dentistry, Louisville, KY, USA.
Perpich JD; Department of Oral Immunology and Infectious Diseases, University of Louisville School of Dentistry, Louisville, KY, USA.
Stocke KS; Department of Oral Immunology and Infectious Diseases, University of Louisville School of Dentistry, Louisville, KY, USA.
Yakoumatos L; Department of Oral Immunology and Infectious Diseases, University of Louisville School of Dentistry, Louisville, KY, USA.
Fitzsimonds ZR; Department of Oral Immunology and Infectious Diseases, University of Louisville School of Dentistry, Louisville, KY, USA.
Liu C; Department of Oral Immunology and Infectious Diseases, University of Louisville School of Dentistry, Louisville, KY, USA.
Miller DP; Department of Oral Immunology and Infectious Diseases, University of Louisville School of Dentistry, Louisville, KY, USA.
Lamont RJ; Department of Oral Immunology and Infectious Diseases, University of Louisville School of Dentistry, Louisville, KY, USA.
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Źródło :
Molecular oral microbiology [Mol Oral Microbiol] 2020 Dec; Vol. 35 (6), pp. 231-239. Date of Electronic Publication: 2020 Oct 05.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Porphyromonas gingivalis*/genetics
Porphyromonas gingivalis*/pathogenicity
Virulence*
Bacterial Proteins/*genetics
Adhesins, Bacterial/genetics ; Alveolar Bone Loss/microbiology ; Animals ; Bacterial Proteins/metabolism ; Bacterial Secretion Systems ; Gingipain Cysteine Endopeptidases ; Mice ; Mutation ; Promoter Regions, Genetic ; Protein-Arginine Deiminases ; Recombinant Proteins ; Streptococcus gordonii ; Virulence Factors
Czasopismo naukowe
Tytuł :
Evaluation of peptidylarginine deiminase 4 and PADI4 polymorphisms in sepsis-induced acute kidney injury.
Autorzy :
Costa NA; Professora Adjunta da Faculdade de Nutrição da Universidade Federal de Goiás - UFG, Goiania, GO, Brasil.
Polegato BF; Professor(a) Associado(a) da Faculdade de Medicina de Botucatu - Unesp, Botucatu, SP, Brasil.
Pereira AG; Aluna do Programa de Pós-graduação em Fisiopatologia em Clínica Médica - Unesp, São Paulo, SP, Brasil.
Paiva SAR; Professor Titular da Faculdade de Medicina de Botucatu - Unesp, Botucatu, SP, Brasil.
Gut AL; Professor(a) Associado(a) da Faculdade de Medicina de Botucatu - Unesp, Botucatu, SP, Brasil.
Balbi AL; Professor(a) Associado(a) da Faculdade de Medicina de Botucatu - Unesp, Botucatu, SP, Brasil.
Ponce D; Médica Livre-docente e Coordenadora do Programa de Pós-graduação em Fisiopatologia em Clínica Médica - Unesp, São Paulo, SP, Brasil.
Zornoff LAM; Professor Titular da Faculdade de Medicina de Botucatu - Unesp, Botucatu, SP, Brasil.
Azevedo PS; Professor(a) Associado(a) da Faculdade de Medicina de Botucatu - Unesp, Botucatu, SP, Brasil.
Minicucci MF; Professor(a) Associado(a) da Faculdade de Medicina de Botucatu - Unesp, Botucatu, SP, Brasil.
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Źródło :
Revista da Associacao Medica Brasileira (1992) [Rev Assoc Med Bras (1992)] 2020 Nov; Vol. 66 (11), pp. 1515-1520.
Typ publikacji :
Journal Article
MeSH Terms :
Acute Kidney Injury*/genetics
Sepsis*
Humans ; Intensive Care Units ; Protein-Arginine Deiminases/genetics ; Renal Replacement Therapy
Czasopismo naukowe

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