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Tytuł:
Dysregulation of extracellular matrix and Lysyl Oxidase in Ehlers-Danlos syndrome type IV skin fibroblasts.
Autorzy:
Foehr R; Kin Therapeutics, 300 Professional Center Drive, Suite #311, Novato, CA, 94947, USA.
Anderson K; Kin Therapeutics, 300 Professional Center Drive, Suite #311, Novato, CA, 94947, USA.
Dombrowski O; Kin Therapeutics, 300 Professional Center Drive, Suite #311, Novato, CA, 94947, USA.
Foehr A; Kin Therapeutics, 300 Professional Center Drive, Suite #311, Novato, CA, 94947, USA.
Foehr ED; Kin Therapeutics, 300 Professional Center Drive, Suite #311, Novato, CA, 94947, USA. .
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Źródło:
Orphanet journal of rare diseases [Orphanet J Rare Dis] 2024 Jan 05; Vol. 19 (1), pp. 9. Date of Electronic Publication: 2024 Jan 05.
Typ publikacji:
Journal Article
MeSH Terms:
Protein-Lysine 6-Oxidase*/genetics
Ehlers-Danlos Syndrome*/genetics
Humans ; Skin ; Extracellular Matrix ; Fibrosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Lysyl Oxidase G473A Polymorphism Exacerbates Oral Cancer Development in Humans and Mice.
Autorzy:
Peymanfar Y; The Forsyth Institute, 245 First Street, Cambridge, MA 02142, USA.
Mahjour F; Department of Translational Dental Medicine, Henry M. Goldman School of Dental Medicine, Boston University, 700 Albany Street, Boston, MA 02118, USA.
Shrestha N; Department of Translational Dental Medicine, Henry M. Goldman School of Dental Medicine, Boston University, 700 Albany Street, Boston, MA 02118, USA.
de la Cueva A; Department of Biochemistry, School of Medicine, Boston University, 72 East Concord Street, Boston, MA 02118, USA.
Chen Y; The Forsyth Institute, 245 First Street, Cambridge, MA 02142, USA.
Huang S; Department of Oral Science and Translational Research, College of Dental Medicine, Nova Southeastern University, Fort Lauderdale, FL 33314, USA.
Kirsch KH; Department of Biochemistry, School of Medicine, Boston University, 72 East Concord Street, Boston, MA 02118, USA.
Han X; Department of Oral Science and Translational Research, College of Dental Medicine, Nova Southeastern University, Fort Lauderdale, FL 33314, USA.
Trackman PC; The Forsyth Institute, 245 First Street, Cambridge, MA 02142, USA.; Department of Translational Dental Medicine, Henry M. Goldman School of Dental Medicine, Boston University, 700 Albany Street, Boston, MA 02118, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 May 28; Vol. 24 (11). Date of Electronic Publication: 2023 May 28.
Typ publikacji:
Journal Article
MeSH Terms:
Mouth Neoplasms*/genetics
Protein-Lysine 6-Oxidase*/metabolism
Animals ; Humans ; Mice ; Carcinogens ; Collagen/genetics ; Polymorphism, Genetic
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Fatty acid binding protein 1 and fatty acid synthetase over-expression have differential effects on collagen III synthesis and cross-linking in Zongdihua pig primary adipocytes.
Autorzy:
Yang R; Guizhou Provincial Breeding Livestock and Poultry Germplasm Determination Center, Guiyang, Guizhou, China.
Zhou D; Guizhou Provincial Breeding Livestock and Poultry Germplasm Determination Center, Guiyang, Guizhou, China.
Yan Z; College of Animal Science, Guizhou University, Guiyang, Guizhou, China.
Zhao Z; Zunyi Animal Husbandry and Fishery Station, Zunyi, Guizhou, China.
Wang Y; Guizhou Provincial Breeding Livestock and Poultry Germplasm Determination Center, Guiyang, Guizhou, China.
Li J; Guizhou Provincial Breeding Livestock and Poultry Germplasm Determination Center, Guiyang, Guizhou, China.
Ren L; Guizhou Provincial Breeding Livestock and Poultry Germplasm Determination Center, Guiyang, Guizhou, China.
Xie L; Guizhou Provincial Breeding Livestock and Poultry Germplasm Determination Center, Guiyang, Guizhou, China.
Wang X; Guizhou Animal Husbandry and Veterinary Research Institute, Guiyang, Guizhou, China.
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Źródło:
PloS one [PLoS One] 2023 May 04; Vol. 18 (5), pp. e0270614. Date of Electronic Publication: 2023 May 04 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Fatty Acids*/metabolism
Protein-Lysine 6-Oxidase*/genetics
Swine ; Animals ; Adipocytes/metabolism ; Collagen/metabolism ; Fatty Acid-Binding Proteins/genetics ; Fatty Acid Synthases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Multifunctional Lysyl Oxidases.
Autorzy:
Trackman PC; The Forsyth Institute, 245 First Street, Cambridge, MA 02142, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Mar 23; Vol. 24 (7). Date of Electronic Publication: 2023 Mar 23.
Typ publikacji:
Editorial
MeSH Terms:
Protein-Lysine 6-Oxidase*/genetics
Protein-Lysine 6-Oxidase*/metabolism
Amino Acid Oxidoreductases*/genetics
Amino Acid Oxidoreductases*/metabolism
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Lysyl oxidase-like 2 processing by factor Xa modulates its activity and substrate preference.
Autorzy:
Wang H; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, 733 N Broadway, Baltimore, MD, 21205, USA.
Poe A; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, 733 N Broadway, Baltimore, MD, 21205, USA.
Martinez Yus M; Department of Chemical and Biomolecular Engineering, Johns Hopkins University Whiting School of Engineering, 3400 N Charles St, Baltimore, MD, 21218, USA.
Pak L; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, 733 N Broadway, Baltimore, MD, 21205, USA.
Nandakumar K; Department of Anesthesiology and CCM, Johns Hopkins University School of Medicine, 733 N Broadway, Baltimore MD, 21205, Baltimore, MD, USA.
Santhanam L; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, 733 N Broadway, Baltimore, MD, 21205, USA. .; Department of Chemical and Biomolecular Engineering, Johns Hopkins University Whiting School of Engineering, 3400 N Charles St, Baltimore, MD, 21218, USA. .; Department of Anesthesiology and CCM, Johns Hopkins University School of Medicine, 733 N Broadway, Baltimore MD, 21205, Baltimore, MD, USA. .
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Źródło:
Communications biology [Commun Biol] 2023 Apr 07; Vol. 6 (1), pp. 375. Date of Electronic Publication: 2023 Apr 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Protein-Lysine 6-Oxidase*/metabolism
Factor Xa*/metabolism
Extracellular Matrix/metabolism ; Myocytes, Smooth Muscle/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Lysyl oxidase inhibits BMP9-induced osteoblastic differentiation through reducing Wnt/β-catenin via HIF-1a repression in 3T3-L1 cells.
Autorzy:
Zhang J; Department of Pharmacology, School of Pharmacy, Chongqing Medical University, No. 1 Yixueyuan Road, Yuzhong, Chongqing, 400016, People's Republic of China.; Key Laboratory of Biochemistry and Molecular Pharmacology of Chongqing, Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Ye F; Department of Pharmacology, School of Pharmacy, Chongqing Medical University, No. 1 Yixueyuan Road, Yuzhong, Chongqing, 400016, People's Republic of China.; Key Laboratory of Biochemistry and Molecular Pharmacology of Chongqing, Chongqing Medical University, Chongqing, 400016, People's Republic of China.
Ye A; Department of Pharmacology, School of Pharmacy, Chongqing Medical University, No. 1 Yixueyuan Road, Yuzhong, Chongqing, 400016, People's Republic of China.; Key Laboratory of Biochemistry and Molecular Pharmacology of Chongqing, Chongqing Medical University, Chongqing, 400016, People's Republic of China.
He B; Department of Pharmacology, School of Pharmacy, Chongqing Medical University, No. 1 Yixueyuan Road, Yuzhong, Chongqing, 400016, People's Republic of China. .; Key Laboratory of Biochemistry and Molecular Pharmacology of Chongqing, Chongqing Medical University, Chongqing, 400016, People's Republic of China. .
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Źródło:
Journal of orthopaedic surgery and research [J Orthop Surg Res] 2023 Nov 29; Vol. 18 (1), pp. 911. Date of Electronic Publication: 2023 Nov 29.
Typ publikacji:
Journal Article
MeSH Terms:
beta Catenin*/genetics
Growth Differentiation Factor 2*/genetics
Growth Differentiation Factor 2*/metabolism
Animals ; Mice ; 3T3-L1 Cells ; Cell Differentiation/genetics ; Osteogenesis/genetics ; Protein-Lysine 6-Oxidase/antagonists & inhibitors ; Protein-Lysine 6-Oxidase/genetics ; Protein-Lysine 6-Oxidase/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Enzymatic lysine oxidation as a posttranslational modification.
Autorzy:
Serra-Bardenys G; Vall d´Hebron Institute of Oncology (VHIO), Barcelona, Spain.
Peiró S; Vall d´Hebron Institute of Oncology (VHIO), Barcelona, Spain.
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Źródło:
The FEBS journal [FEBS J] 2022 Dec; Vol. 289 (24), pp. 8020-8031. Date of Electronic Publication: 2021 Oct 02.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Lysine*/metabolism
Protein-Lysine 6-Oxidase*/metabolism
Amines ; Oxidation-Reduction ; Protein Processing, Post-Translational
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Insight into the Spatial Arrangement of the Lysine Tyrosylquinone and Cu in the Active Site of Lysyl Oxidase-like 2.
Autorzy:
Meier AA; Department of Chemistry, The University of Kansas, Lawrence, KS 66045, USA.
Moon HJ; Department of Chemistry, The University of Kansas, Lawrence, KS 66045, USA.
Sabuncu S; Department of Chemical Physiology and Biochemistry, School of Medicine, Oregon Health & Science University, Portland, OR 97239, USA.
Singh P; Department of Chemistry, The University of Kansas, Lawrence, KS 66045, USA.
Ronnebaum TA; Department of Chemistry, The University of Kansas, Lawrence, KS 66045, USA.
Ou S; Department of Chemistry, The University of Kansas, Lawrence, KS 66045, USA.
Douglas JT; Department of Chemistry, The University of Kansas, Lawrence, KS 66045, USA.
Jackson TA; Department of Chemistry, The University of Kansas, Lawrence, KS 66045, USA.
Moënne-Loccoz P; Department of Chemical Physiology and Biochemistry, School of Medicine, Oregon Health & Science University, Portland, OR 97239, USA.
Mure M; Department of Chemistry, The University of Kansas, Lawrence, KS 66045, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Nov 12; Vol. 23 (22). Date of Electronic Publication: 2022 Nov 12.
Typ publikacji:
Journal Article
MeSH Terms:
Lysine*/metabolism
Protein-Lysine 6-Oxidase*/metabolism
Catalytic Domain ; Quinones/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A 3D-Predicted Structure of the Amine Oxidase Domain of Lysyl Oxidase-Like 2.
Autorzy:
Meier AA; Department of Chemistry, The University of Kansas, Lawrence, KS 66045, USA.
Kuczera K; Department of Chemistry, The University of Kansas, Lawrence, KS 66045, USA.; Department of Molecular Biosciences, University of Kansas, Lawrence, KS 66045, USA.
Mure M; Department of Chemistry, The University of Kansas, Lawrence, KS 66045, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Nov 02; Vol. 23 (21). Date of Electronic Publication: 2022 Nov 02.
Typ publikacji:
Journal Article
MeSH Terms:
Protein-Lysine 6-Oxidase*/chemistry
Quinones*/chemistry
Models, Molecular ; Monoamine Oxidase ; Amines ; Amino Acid Oxidoreductases/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Collagen cross-links scale with passive stiffness in dystrophic mouse muscles, but are not altered with administration of a lysyl oxidase inhibitor.
Autorzy:
Brashear SE; Department of Neurobiology, Physiology, and Behavior, University of California Davis, Davis, California, United States of America.
Wohlgemuth RP; Department of Neurobiology, Physiology, and Behavior, University of California Davis, Davis, California, United States of America.
Hu LY; Department of Neurobiology, Physiology, and Behavior, University of California Davis, Davis, California, United States of America.
Jbeily EH; Department of Orthopaedic Surgery, University of California Davis, Sacramento, California, United States of America.
Christiansen BA; Department of Orthopaedic Surgery, University of California Davis, Sacramento, California, United States of America.
Smith LR; Department of Neurobiology, Physiology, and Behavior, University of California Davis, Davis, California, United States of America.; Department of Physical Medicine and Rehabilitation, University of California Davis, Sacramento, California, United States of America.
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Źródło:
PloS one [PLoS One] 2022 Oct 27; Vol. 17 (10), pp. e0271776. Date of Electronic Publication: 2022 Oct 27 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Muscular Dystrophy, Duchenne*
Protein-Lysine 6-Oxidase*/antagonists & inhibitors
Animals ; Mice ; Aminopropionitrile/pharmacology ; Collagen ; Disease Models, Animal ; Fibrosis ; Mice, Inbred mdx ; Muscle, Skeletal/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Lysyl Oxidase Family Proteins: Prospective Therapeutic Targets in Cancer.
Autorzy:
Wang W; Department of Hepatobiliary and Pancreatic Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200233, China.
Wang X; Department of Hepatobiliary and Pancreatic Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200233, China.
Yao F; Thoracic Oncology Institute, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai 200030, China.
Huang C; Department of Cell Biology, Medical School, Kunming University of Science and Technology, Kunming 650500, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Oct 14; Vol. 23 (20). Date of Electronic Publication: 2022 Oct 14.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Protein-Lysine 6-Oxidase*/metabolism
Neoplasms*/therapy
Neoplasms*/metabolism
Humans ; Elastin/metabolism ; Extracellular Matrix/metabolism ; Collagen/metabolism ; Tumor Microenvironment
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Lysyl Oxidases: Orchestrators of Cellular Behavior and ECM Remodeling and Homeostasis.
Autorzy:
Zaffryar-Eilot S; Department of Genetics and Developmental Biology, The Rappaport Faculty of Medicine and Research Institute, Technion-Israel Institute of Technology, Haifa 3525422, Israel.
Hasson P; Department of Genetics and Developmental Biology, The Rappaport Faculty of Medicine and Research Institute, Technion-Israel Institute of Technology, Haifa 3525422, Israel.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Sep 27; Vol. 23 (19). Date of Electronic Publication: 2022 Sep 27.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Elastin*
Protein-Lysine 6-Oxidase*
Collagen ; Extracellular Matrix ; Homeostasis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Copper-Binding Domain Variation in a Novel Murine Lysyl Oxidase Model Produces Structurally Inferior Aortic Elastic Fibers Whose Failure Is Modified by Age, Sex, and Blood Pressure.
Autorzy:
Tsang KM; National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Knutsen RH; National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Billington CJ Jr; National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.; Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA.
Lindberg E; National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Steenbock H; Institute of Virology and Cell Biology, University of Lübeck, 23562 Lübeck, Germany.
Fu YP; National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Wardlaw-Pickett A; National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.; Johns Hopkins University Applied Physics Lab, Laurel, MD 20724, USA.
Liu D; National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Malide D; National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Yu ZX; National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Bleck CKE; National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Brinckmann J; Institute of Virology and Cell Biology, University of Lübeck, 23562 Lübeck, Germany.; Department of Dermatology, University of Lübeck, 23562 Lübeck, Germany.
Kozel BA; National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Jun 17; Vol. 23 (12). Date of Electronic Publication: 2022 Jun 17.
Typ publikacji:
Journal Article
MeSH Terms:
Elastic Tissue*/metabolism
Protein-Lysine 6-Oxidase*/genetics
Protein-Lysine 6-Oxidase*/metabolism
Animals ; Aorta/metabolism ; Blood Pressure ; Copper ; Dilatation, Pathologic/pathology ; Female ; Male ; Mice ; Mice, Inbred C57BL
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Pan-Lysyl Oxidase Inhibitor PXS-5505 Ameliorates Multiple-Organ Fibrosis by Inhibiting Collagen Crosslinks in Rodent Models of Systemic Sclerosis.
Autorzy:
Yao Y; Drug Discovery, Pharmaxis Ltd., Sydney, NSW 2086, Australia.
Findlay A; Drug Discovery, Pharmaxis Ltd., Sydney, NSW 2086, Australia.
Stolp J; Drug Discovery, Pharmaxis Ltd., Sydney, NSW 2086, Australia.
Rayner B; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Kensington, Sydney, NSW 2031, Australia.
Ask K; Division of Respirology, Department of Medicine, McMaster University, Hamilton, ON L8N 3Z5, Canada.
Jarolimek W; Drug Discovery, Pharmaxis Ltd., Sydney, NSW 2086, Australia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 May 16; Vol. 23 (10). Date of Electronic Publication: 2022 May 16.
Typ publikacji:
Journal Article
MeSH Terms:
Collagen*/antagonists & inhibitors
Collagen*/metabolism
Enzyme Inhibitors*
Protein-Lysine 6-Oxidase*/antagonists & inhibitors
Protein-Lysine 6-Oxidase*/metabolism
Scleroderma, Systemic*/drug therapy
Scleroderma, Systemic*/enzymology
Animals ; Disease Models, Animal ; Fibrosis ; Humans ; Mice ; Rodentia/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Lysyl Oxidase Family Enzymes and Their Role in Tumor Progression.
Autorzy:
Liburkin-Dan T; Cancer Research and Vascular Biology Center, The Bruce Rappaport Faculty of Medicine, Technion, Israel Institute of Technology, Haifa 31096, Israel.
Toledano S; Cancer Research and Vascular Biology Center, The Bruce Rappaport Faculty of Medicine, Technion, Israel Institute of Technology, Haifa 31096, Israel.
Neufeld G; Cancer Research and Vascular Biology Center, The Bruce Rappaport Faculty of Medicine, Technion, Israel Institute of Technology, Haifa 31096, Israel.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Jun 02; Vol. 23 (11). Date of Electronic Publication: 2022 Jun 02.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Neoplasms*/genetics
Protein-Lysine 6-Oxidase*/genetics
Amino Acid Oxidoreductases/genetics ; Collagen ; Extracellular Matrix ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Mass Spectrometry-Based Disulfide Mapping of Lysyl Oxidase-like 2.
Autorzy:
Meier AA; Department of Chemistry, The University of Kansas, Lawrence, KS 66045, USA.
Go EP; Department of Chemistry, The University of Kansas, Lawrence, KS 66045, USA.
Moon HJ; Department of Chemistry, The University of Kansas, Lawrence, KS 66045, USA.
Desaire H; Department of Chemistry, The University of Kansas, Lawrence, KS 66045, USA.
Mure M; Department of Chemistry, The University of Kansas, Lawrence, KS 66045, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 May 24; Vol. 23 (11). Date of Electronic Publication: 2022 May 24.
Typ publikacji:
Journal Article
MeSH Terms:
Disulfides*
Protein-Lysine 6-Oxidase*/metabolism
Amino Acid Oxidoreductases/metabolism ; Extracellular Matrix/metabolism ; Mass Spectrometry ; Protein Processing, Post-Translational
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Functions and Mechanisms of Pro-Lysyl Oxidase Processing in Cancers and Eye Pathologies with a Focus on Diabetic Retinopathy.
Autorzy:
Trackman PC; The Forsyth Institute, 245 First Street, Cambridge, MA 02142, USA.; Department of Translational Dental Medicine, Boston University Henry M Goldman School of Dental Medicine, 700 Albany Street, Boston, MA 02118, USA.
Peymanfar Y; The Forsyth Institute, 245 First Street, Cambridge, MA 02142, USA.
Roy S; Department of Medicine, Boston University School of Medicine, 650 Albany Street, Boston, MA 02118, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 May 03; Vol. 23 (9). Date of Electronic Publication: 2022 May 03.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Diabetes Mellitus*/enzymology
Diabetes Mellitus*/metabolism
Diabetic Retinopathy*/enzymology
Diabetic Retinopathy*/metabolism
Neoplasms*/enzymology
Neoplasms*/metabolism
Protein-Lysine 6-Oxidase*/metabolism
Collagen/metabolism ; Humans ; Peptides
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
LOXL2 in Cancer: A Two-Decade Perspective.
Autorzy:
Cano A; Departamento de Bioquímica UAM, Instituto de Investigaciones Biomédicas Alberto Sols, Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid (CSIC-UAM), 28029 Madrid, Spain.; Instituto de Investigación Sanitaria del Hospital Universitario La Paz-IdiPAZ, 28029 Madrid, Spain.; Centro de Investigación Biomédica en Red, Área de Cáncer (CIBERONC), Instituto de Salud Carlos III, 28029 Madrid, Spain.
Eraso P; Departamento de Bioquímica UAM, Instituto de Investigaciones Biomédicas Alberto Sols, Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid (CSIC-UAM), 28029 Madrid, Spain.; Instituto de Investigación Sanitaria del Hospital Universitario La Paz-IdiPAZ, 28029 Madrid, Spain.
Mazón MJ; Departamento de Bioquímica UAM, Instituto de Investigaciones Biomédicas Alberto Sols, Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid (CSIC-UAM), 28029 Madrid, Spain.; Instituto de Investigación Sanitaria del Hospital Universitario La Paz-IdiPAZ, 28029 Madrid, Spain.
Portillo F; Departamento de Bioquímica UAM, Instituto de Investigaciones Biomédicas Alberto Sols, Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid (CSIC-UAM), 28029 Madrid, Spain.; Instituto de Investigación Sanitaria del Hospital Universitario La Paz-IdiPAZ, 28029 Madrid, Spain.; Centro de Investigación Biomédica en Red, Área de Cáncer (CIBERONC), Instituto de Salud Carlos III, 28029 Madrid, Spain.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Sep 21; Vol. 24 (18). Date of Electronic Publication: 2023 Sep 21.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Neoplasms*/genetics
Amine Oxidase (Copper-Containing)*
Animals ; Mice ; Humans ; Protein-Lysine 6-Oxidase ; Disease Models, Animal ; Promoter Regions, Genetic ; Amino Acid Oxidoreductases/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cleavage of LOXL1 by BMP1 and ADAMTS14 Proteases Suggests a Role for Proteolytic Processing in the Regulation of LOXL1 Function.
Autorzy:
Rosell-García T; Centro de Biología Molecular 'Severo Ochoa' Consejo Superior de Investigaciones Científicas (C.S.I.C.), Universidad Autónoma de Madrid, E-28049 Madrid, Spain.
Rivas-Muñoz S; Centro de Biología Molecular 'Severo Ochoa' Consejo Superior de Investigaciones Científicas (C.S.I.C.), Universidad Autónoma de Madrid, E-28049 Madrid, Spain.
Colige A; Laboratory of Connective Tissues Biology, GIGA, University of Liège, Sart Tilman, 4000 Liège, Belgium.
Rodriguez-Pascual F; Centro de Biología Molecular 'Severo Ochoa' Consejo Superior de Investigaciones Científicas (C.S.I.C.), Universidad Autónoma de Madrid, E-28049 Madrid, Spain.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Mar 18; Vol. 23 (6). Date of Electronic Publication: 2022 Mar 18.
Typ publikacji:
Journal Article
MeSH Terms:
Exfoliation Syndrome*/genetics
Protein-Lysine 6-Oxidase*/metabolism
ADAMTS Proteins/metabolism ; Amino Acid Oxidoreductases/genetics ; Amino Acid Oxidoreductases/metabolism ; Bone Morphogenetic Protein 1/genetics ; Bone Morphogenetic Protein 1/metabolism ; Humans ; Peptide Hydrolases/metabolism ; Proteolysis ; Proteomics
Czasopismo naukowe
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Tytuł:
Experimental aortic aneurysm severity and growth depend on topical elastase concentration and lysyl oxidase inhibition.
Autorzy:
Berman AG; Weldon School of Biomedical Engineering, Purdue University, 206 S. Martin Jischke Drive, West Lafayette, IN, 47907, USA.
Romary DJ; Weldon School of Biomedical Engineering, Purdue University, 206 S. Martin Jischke Drive, West Lafayette, IN, 47907, USA.
Kerr KE; Weldon School of Biomedical Engineering, Purdue University, 206 S. Martin Jischke Drive, West Lafayette, IN, 47907, USA.
Gorazd NE; Weldon School of Biomedical Engineering, Purdue University, 206 S. Martin Jischke Drive, West Lafayette, IN, 47907, USA.
Wigand MM; Weldon School of Biomedical Engineering, Purdue University, 206 S. Martin Jischke Drive, West Lafayette, IN, 47907, USA.
Patnaik SS; Department of Mechanical Engineering, University of Texas at San Antonio, San Antonio, TX, USA.
Finol EA; Department of Mechanical Engineering, University of Texas at San Antonio, San Antonio, TX, USA.
Cox AD; Department of Comparative Pathobiology, Purdue University, West Lafayette, IN, USA.
Goergen CJ; Weldon School of Biomedical Engineering, Purdue University, 206 S. Martin Jischke Drive, West Lafayette, IN, 47907, USA. .; Purdue Center for Cancer Research, Purdue University, West Lafayette, IN, USA. .
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Źródło:
Scientific reports [Sci Rep] 2022 Jan 07; Vol. 12 (1), pp. 99. Date of Electronic Publication: 2022 Jan 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Aminopropionitrile*
Pancreatic Elastase*
Aorta, Abdominal/*enzymology
Aortic Aneurysm, Abdominal/*chemically induced
Protein-Lysine 6-Oxidase/*antagonists & inhibitors
Administration, Topical ; Animals ; Aorta, Abdominal/pathology ; Aortic Aneurysm, Abdominal/enzymology ; Aortic Aneurysm, Abdominal/pathology ; Dilatation, Pathologic ; Disease Models, Animal ; Disease Progression ; Female ; Male ; Mice, Inbred C57BL ; Protein-Lysine 6-Oxidase/metabolism ; Severity of Illness Index ; Mice
Czasopismo naukowe
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Wyświetlanie 1-20 z 263

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