Temat: "Protein-Serine-Threonine Kinases" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Identification and functional activity of Nik related kinase (NRK) in benign hyperplastic prostate.
Autorzy:: He W; Department of Urology, Xijing Hospital of Air Force Medical University, West Changle Road 127, Xi'an, China. .
Tian Z; Department of Hepatobiliary Surgery, Xijing Hospital of Air Force Medical University, Xi'an, China.
Dong B; Department of Orthopedics, Ninth Hospital of Xi'an, Xi'an, China.
Cao Y; Department of Urology, Xijing Hospital of Air Force Medical University, West Changle Road 127, Xi'an, China.
Hu W; Department of Urology, Xijing Hospital of Air Force Medical University, West Changle Road 127, Xi'an, China.
Wu P; Department of Urology, Xijing Hospital of Air Force Medical University, West Changle Road 127, Xi'an, China.
Yu L; Department of Urology, Xijing Hospital of Air Force Medical University, West Changle Road 127, Xi'an, China.
Zhang X; Department of Urology, Zhongnan Hospital of Wuhan University, Donghu Road 169, Wuhan, China. .
Guo S; Department of Physiology and Pathophysiology, Air Force Medical University, West Changle Road 169, Xi'an, China. .; Pokaż więcej
Źródło:: Journal of translational medicine [J Transl Med] 2024 Mar 09; Vol. 22 (1), pp. 255. Date of Electronic Publication: 2024 Mar 09.
Typ publikacji:: Journal Article
MeSH Terms:: Prostate*/metabolism
Prostatic Hyperplasia*/genetics
Prostatic Hyperplasia*/metabolism
Prostatic Hyperplasia*/pathology
Protein Serine-Threonine Kinases*
Intracellular Signaling Peptides and Proteins*
Male ; Humans ; Aged ; Hyperplasia/metabolism ; Hyperplasia/pathology ; Fibrosis

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Skocz do pozycji: 2.

Tytuł:: Indoxyl Sulfate-Induced Valve Endothelial Cell Endothelial-to-Mesenchymal Transition and Calcification in an Integrin-Linked Kinase-Dependent Manner.
Autorzy:: Delgado-Marin M; Unidad de Fisiología, Departamento de Biología de Sistemas, Facultad de Medicina, IRYCIS, Universidad de Alcalá, 28871 Alcalá de Henares, Spain.
Sánchez-Esteban S; Unidad de Fisiología, Departamento de Biología de Sistemas, Facultad de Medicina, IRYCIS, Universidad de Alcalá, 28871 Alcalá de Henares, Spain.
Cook-Calvete A; Unidad de Fisiología, Departamento de Biología de Sistemas, Facultad de Medicina, IRYCIS, Universidad de Alcalá, 28871 Alcalá de Henares, Spain.
Jorquera-Ortega S; Unidad de Fisiología, Departamento de Biología de Sistemas, Facultad de Medicina, IRYCIS, Universidad de Alcalá, 28871 Alcalá de Henares, Spain.
Zaragoza C; Cardiovascular Research University Francisco de Vitoria and Hospital Ramon y Cajal, IRYCIS, 28034 Madrid, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Instituto de Salud Carlos III, 28029 Madrid, Spain.
Saura M; Unidad de Fisiología, Departamento de Biología de Sistemas, Facultad de Medicina, IRYCIS, Universidad de Alcalá, 28871 Alcalá de Henares, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Instituto de Salud Carlos III, 28029 Madrid, Spain.; Pokaż więcej
Źródło:: Cells [Cells] 2024 Mar 08; Vol. 13 (6). Date of Electronic Publication: 2024 Mar 08.
Typ publikacji:: Journal Article
MeSH Terms:: Vascular Calcification*/metabolism
Renal Insufficiency, Chronic*/pathology
Aortic Valve Stenosis*
Calcinosis*
Protein Serine-Threonine Kinases*
Aortic Valve/*pathology
Humans ; Indican ; Core Binding Factor Alpha 1 Subunit/metabolism ; Endothelial Cells/metabolism ; Cells, Cultured
SCR Disease Name:: Aortic Valve, Calcification of

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Skocz do pozycji: 3.

Tytuł:: The Mitochondrial Connection: The Nek Kinases' New Functional Axis in Mitochondrial Homeostasis.
Autorzy:: Basei FL; Faculty of Pharmaceutical Sciences, University of Campinas, Campinas 13083-871, Brazil.
E Silva IR; Faculty of Pharmaceutical Sciences, University of Campinas, Campinas 13083-871, Brazil.
Dias PRF; Faculty of Pharmaceutical Sciences, University of Campinas, Campinas 13083-871, Brazil.
Ferezin CC; Faculty of Pharmaceutical Sciences, University of Campinas, Campinas 13083-871, Brazil.
Peres de Oliveira A; Faculty of Pharmaceutical Sciences, University of Campinas, Campinas 13083-871, Brazil.
Issayama LK; Faculty of Pharmaceutical Sciences, University of Campinas, Campinas 13083-871, Brazil.
Moura LAR; Faculty of Pharmaceutical Sciences, University of Campinas, Campinas 13083-871, Brazil.
da Silva FR; Faculty of Pharmaceutical Sciences, University of Campinas, Campinas 13083-871, Brazil.
Kobarg J; Faculty of Pharmaceutical Sciences, University of Campinas, Campinas 13083-871, Brazil.; Pokaż więcej
Źródło:: Cells [Cells] 2024 Mar 07; Vol. 13 (6). Date of Electronic Publication: 2024 Mar 07.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Protein Serine-Threonine Kinases*/metabolism
Mitochondria*/metabolism
NIMA-Related Kinases/metabolism ; Homeostasis ; DNA, Mitochondrial

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Skocz do pozycji: 4.

Tytuł:: Pan-cancer analysis reveals PDK family as potential indicators related to prognosis and immune infiltration.
Autorzy:: Tao S; The Second Affiliated Hospital of Guangxi Medical University, Nanning, China.
Tao K; Guiping People's Hospital, Guangxi, China.
Cai X; The Second Affiliated Hospital of Guangxi Medical University, Nanning, China. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Mar 07; Vol. 14 (1), pp. 5665. Date of Electronic Publication: 2024 Mar 07.
Typ publikacji:: Journal Article
MeSH Terms:: Protein Serine-Threonine Kinases*/metabolism
Neoplasms*/metabolism
Humans ; Pyruvate Dehydrogenase Acetyl-Transferring Kinase/genetics ; Prognosis ; Pyruvates ; Pyruvate Dehydrogenase Complex/metabolism

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Skocz do pozycji: 5.

Tytuł:: Emerging Role of GCN1 in Disease and Homeostasis.
Autorzy:: Tatara Y; Department of Stress Response Science, Biomedical Research Center, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki 036-8562, Aomori, Japan.
Kasai S; Department of Stress Response Science, Biomedical Research Center, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki 036-8562, Aomori, Japan.
Kokubu D; Diet and Well-Being Research Institute, KAGOME, Co., Ltd., 17 Nishitomiyama, Nasushiobara 329-2762, Tochigi, Japan.; Department of Vegetable Life Science, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki 036-8562, Aomori, Japan.
Tsujita T; Laboratory of Biochemistry, Department of Applied Biochemistry and Food Science, Faculty of Agriculture, Saga University, 1 Honjo-machi, Saga City 840-8502, Saga, Japan.
Mimura J; Department of Stress Response Science, Biomedical Research Center, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki 036-8562, Aomori, Japan.
Itoh K; Department of Stress Response Science, Biomedical Research Center, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki 036-8562, Aomori, Japan.; Department of Vegetable Life Science, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki 036-8562, Aomori, Japan.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 05; Vol. 25 (5). Date of Electronic Publication: 2024 Mar 05.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Protein Serine-Threonine Kinases*/metabolism
Animals ; Humans ; Mice ; Amino Acids/metabolism ; Homeostasis ; Peptide Elongation Factors/metabolism ; RNA-Binding Proteins/metabolism ; Trans-Activators/metabolism

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Skocz do pozycji: 6.

Tytuł:: Expression of the checkpoint kinase BUB1 is a predictor of response to cancer therapies.
Autorzy:: Cicirò Y; Centre for Inflammation Research and Translational Medicine (CIRTM), Brunel University London, Uxbridge, UB8 3PH, UK.
Ragusa D; Centre for Genome Engineering and Maintenance (CenGEM), Brunel University London, Uxbridge, UB8 3PH, UK. .
Sala A; Centre for Inflammation Research and Translational Medicine (CIRTM), Brunel University London, Uxbridge, UB8 3PH, UK. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Feb 23; Vol. 14 (1), pp. 4461. Date of Electronic Publication: 2024 Feb 23.
Typ publikacji:: Journal Article
MeSH Terms:: Protein Serine-Threonine Kinases*/metabolism
Neoplasms*/drug therapy
Neoplasms*/genetics
Humans ; Mitosis/genetics ; Cell Cycle Proteins/genetics ; Cell Cycle Proteins/metabolism

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Skocz do pozycji: 7.

Tytuł:: Spatiotemporal expression and coexpression patterns of SRPK1 in the human brain: A neurodevelopmental perspective.
Autorzy:: Wang JJ; Department of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, Henan, P. R. China.
Roy SK; Department of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, Henan, P. R. China.
Xu YM; Department of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, Henan, P. R. China.; Pokaż więcej
Źródło:: Brain and behavior [Brain Behav] 2024 Jan; Vol. 14 (1), pp. e3341.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Protein Serine-Threonine Kinases*/genetics
Protein Serine-Threonine Kinases*/metabolism
Transcriptome*
Adult ; Humans ; Brain/metabolism

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Skocz do pozycji: 8.

Tytuł:: Endoplasmic reticulum stress mediates environmental particle-induced inflammatory response in bronchial epithelium.
Autorzy:: Pu L; Department of Respiratory and Critical Care Medicine, First Affiliated Hospital of Anhui Medical University, and Anhui Medical University, Hefei, China.
Yi F; Department of Respiratory and Critical Care Medicine, First Affiliated Hospital of Anhui Medical University, and Anhui Medical University, Hefei, China.
Yu WJ; Department of Respiratory and Critical Care Medicine, First Affiliated Hospital of Anhui Medical University, and Anhui Medical University, Hefei, China.
Li YJ; Department of Respiratory and Critical Care Medicine, First Affiliated Hospital of Anhui Medical University, and Anhui Medical University, Hefei, China.
Tu YH; Department of Respiratory and Critical Care Medicine, First Affiliated Hospital of Anhui Medical University, and Anhui Medical University, Hefei, China.
Xu AH; Department of Respiratory and Critical Care Medicine, First Affiliated Hospital of Anhui Medical University, and Anhui Medical University, Hefei, China.
Wang Y; Department of Respiratory and Critical Care Medicine, First Affiliated Hospital of Anhui Medical University, and Anhui Medical University, Hefei, China.; Pokaż więcej
Źródło:: Journal of immunotoxicology [J Immunotoxicol] 2023 Dec; Vol. 20 (1), pp. 2229428.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: NF-kappa B*/metabolism
Protein Serine-Threonine Kinases*/genetics
Protein Serine-Threonine Kinases*/metabolism
Protein Serine-Threonine Kinases*/pharmacology
Humans ; Endoribonucleases/genetics ; Endoribonucleases/metabolism ; Endoribonucleases/pharmacology ; Endoplasmic Reticulum Chaperone BiP ; Inflammation ; Particulate Matter/toxicity ; Epithelium/metabolism ; Endoplasmic Reticulum Stress ; RNA, Small Interfering/genetics ; RNA, Small Interfering/pharmacology

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Skocz do pozycji: 9.

Tytuł:: A missense mutation of the WNK1 gene affects cold tolerance in Chinese domestic cattle.
Autorzy:: Liu X; Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, China.
Chen J; Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, China.
Xu X; Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, China.
Liu J; Yunnan Academy of Grassland and Animal Science, Kunming, China.
Zhang J; Yunnan Academy of Grassland and Animal Science, Kunming, China.
Cheng H; Shandong Key Lab of Animal Disease Control and Breeding, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan, China.
Ahmed Z; Faculty of Veterinary and Animal Sciences, University of Poonch Rawalakot Azad Jammu and Kashmir Pakistan, Rawalakot, Pakistan.
Huang B; Yunnan Academy of Grassland and Animal Science, Kunming, China.
Lei C; Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, China.; Pokaż więcej
Źródło:: Animal biotechnology [Anim Biotechnol] 2023 Dec; Vol. 34 (9), pp. 4803-4808. Date of Electronic Publication: 2023 Apr 20.
Typ publikacji:: Journal Article
MeSH Terms:: Protein Serine-Threonine Kinases*/genetics
Protein Serine-Threonine Kinases*/metabolism
Mutation, Missense*
Humans ; Cattle/genetics ; Animals ; WNK Lysine-Deficient Protein Kinase 1/genetics ; Minor Histocompatibility Antigens/genetics ; China

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Skocz do pozycji: 10.

Tytuł:: Convergent and divergent roles of the glucose-responsive kinase SNF4 in Candida tropicalis .
Autorzy:: Ke CL; Department of Biochemical Science and Technology, College of Life Science, National Taiwan University, Taipei, Taiwan.
Lew SQ; Department of Biochemical Science and Technology, College of Life Science, National Taiwan University, Taipei, Taiwan.
Hsieh Y; Department of Biochemical Science and Technology, College of Life Science, National Taiwan University, Taipei, Taiwan.
Chang SC; Department of Biochemical Science and Technology, College of Life Science, National Taiwan University, Taipei, Taiwan.
Lin CH; Department of Biochemical Science and Technology, College of Life Science, National Taiwan University, Taipei, Taiwan.; Pokaż więcej
Źródło:: Virulence [Virulence] 2023 Dec; Vol. 14 (1), pp. 2175914.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: AMP-Activated Protein Kinases*/genetics
AMP-Activated Protein Kinases*/metabolism
Candida tropicalis*/genetics
Protein Serine-Threonine Kinases*/genetics
Protein Serine-Threonine Kinases*/metabolism
Animals ; Glucose/metabolism ; Mammals ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae Proteins/genetics ; Transcription Factors/genetics

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Skocz do pozycji: 11.

Tytuł:: Regulation of the Hippo/YAP axis by CXCR7 in the tumorigenesis of gastric cancer.
Autorzy:: Wang T; Department of General Surgery, The Second Hospital of Shandong University, Cheeloo College of Medicine, Shandong University, Jinan, 250033, China.
Wang D; Department of General Surgery, The Second Hospital of Shandong University, Cheeloo College of Medicine, Shandong University, Jinan, 250033, China.
Sun Y; Department of General Surgery, The Second Hospital of Shandong University, Cheeloo College of Medicine, Shandong University, Jinan, 250033, China.
Zhuang T; Xinxiang Key Laboratory of Tumor Migration and Invasion Precision Medicine, School of Medical Technology, Xinxiang Medical University, Xinxiang, 453003, Henan Province, P. R. China.; Department of Thoracic Surgery, The Second Hospital, Cheeloo College of Medicine, Shandong University, Shandong Province, P. R. China.
Li X; Xinxiang Key Laboratory of Tumor Migration and Invasion Precision Medicine, School of Medical Technology, Xinxiang Medical University, Xinxiang, 453003, Henan Province, P. R. China.
Yang H; Xinxiang Key Laboratory of Tumor Migration and Invasion Precision Medicine, School of Medical Technology, Xinxiang Medical University, Xinxiang, 453003, Henan Province, P. R. China.
Zang Y; Department of General Surgery, The Second Hospital of Shandong University, Cheeloo College of Medicine, Shandong University, Jinan, 250033, China.
Liu Z; Department of General Surgery, The Second Hospital of Shandong University, Cheeloo College of Medicine, Shandong University, Jinan, 250033, China.
Yang P; Xinxiang Key Laboratory of Tumor Migration and Invasion Precision Medicine, School of Medical Technology, Xinxiang Medical University, Xinxiang, 453003, Henan Province, P. R. China.
Zhang C; Xinxiang Key Laboratory of Tumor Migration and Invasion Precision Medicine, School of Medical Technology, Xinxiang Medical University, Xinxiang, 453003, Henan Province, P. R. China.
Cui J; Xinxiang Key Laboratory of Tumor Migration and Invasion Precision Medicine, School of Medical Technology, Xinxiang Medical University, Xinxiang, 453003, Henan Province, P. R. China.
Fu M; Xinxiang Key Laboratory of Tumor Migration and Invasion Precision Medicine, School of Medical Technology, Xinxiang Medical University, Xinxiang, 453003, Henan Province, P. R. China.
Zhang S; Xinxiang Key Laboratory of Tumor Migration and Invasion Precision Medicine, School of Medical Technology, Xinxiang Medical University, Xinxiang, 453003, Henan Province, P. R. China.
Su P; Department of Pathology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250033, China. .
Li Z; Xinxiang Key Laboratory of Tumor Migration and Invasion Precision Medicine, School of Medical Technology, Xinxiang Medical University, Xinxiang, 453003, Henan Province, P. R. China. .
Zhu J; Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang, China. .
Ding Y; Department of General Surgery, The Second Hospital of Shandong University, Cheeloo College of Medicine, Shandong University, Jinan, 250033, China. .; Pokaż więcej
Źródło:: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2023 Nov 10; Vol. 42 (1), pp. 297. Date of Electronic Publication: 2023 Nov 10.
Typ publikacji:: Journal Article
MeSH Terms:: Protein Serine-Threonine Kinases*/genetics
Protein Serine-Threonine Kinases*/metabolism
Stomach Neoplasms*/genetics
Stomach Neoplasms*/metabolism
Humans ; Adaptor Proteins, Signal Transducing/genetics ; Adaptor Proteins, Signal Transducing/metabolism ; Carcinogenesis/genetics ; Cell Line, Tumor ; Cell Proliferation ; Cell Transformation, Neoplastic ; Transcription Factors/genetics ; Transcription Factors/metabolism ; YAP-Signaling Proteins

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Skocz do pozycji: 12.

Tytuł:: ULK2 Is a Key Pro-Autophagy Protein That Contributes to the High Chemoresistance and Disease Relapse in FLT3-Mutated Acute Myeloid Leukemia.
Autorzy:: Lai J; Department of Medicine, Division of Hematology, University of Alberta, Edmonton, AB T6G 2R3, Canada.
Yang C; Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB T6G 2R3, Canada.
Shang C; Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB T6G 2R3, Canada.
Chen W; Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB T6G 2R3, Canada.
Chu MP; Department of Medicine, Division of Hematology, University of Alberta, Edmonton, AB T6G 2R3, Canada.; Department of Medical Oncology, Cross Cancer Institute, Edmonton, AB T6G 1Z2, Canada.
Brandwein J; Department of Medicine, Division of Hematology, University of Alberta, Edmonton, AB T6G 2R3, Canada.
Lai R; Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB T6G 2R3, Canada.; Department of Medical Oncology, Cross Cancer Institute, Edmonton, AB T6G 1Z2, Canada.
Wang P; Department of Medicine, Division of Hematology, University of Alberta, Edmonton, AB T6G 2R3, Canada.; Department of Medical Oncology, Cross Cancer Institute, Edmonton, AB T6G 1Z2, Canada.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2024 Jan 04; Vol. 25 (1). Date of Electronic Publication: 2024 Jan 04.
Typ publikacji:: Journal Article
MeSH Terms:: Drug Resistance, Neoplasm*/genetics
Leukemia, Myeloid, Acute*/drug therapy
Leukemia, Myeloid, Acute*/genetics
Protein Serine-Threonine Kinases*/genetics
Humans ; Autophagy/genetics ; Biological Assay ; Chronic Disease ; Cytarabine/pharmacology ; fms-Like Tyrosine Kinase 3/genetics

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Skocz do pozycji: 13.

Tytuł:: Safety, pharmacokinetics, and target engagement of a brain penetrant RIPK1 inhibitor, SAR443820 (DNL788), in healthy adult participants.
Autorzy:: Hincelin-Mery A; Sanofi, Chilly-Mazarin, France.
Nicolas X; Sanofi, Montpellier, France.
Cantalloube C; Sanofi, Chilly-Mazarin, France.
Pomponio R; Sanofi, Cambridge, Massachusetts, USA.
Lewanczyk P; Ividata Life Sciences, Levallois-Perret, France.
Benamor M; Sanofi, Chilly-Mazarin, France.
Ofengeim D; Sanofi, Cambridge, Massachusetts, USA.
Krupka E; Sanofi, Montpellier, France.
Hsiao-Nakamoto J; Denali Therapeutics Inc., South San Francisco, California, USA.
Eastenson A; Nucleus Network Pty Ltd., St. Paul, Minnesota, USA.
Atassi N; Sanofi, Cambridge, Massachusetts, USA.; Pokaż więcej
Źródło:: Clinical and translational science [Clin Transl Sci] 2024 Jan; Vol. 17 (1), pp. e13690. Date of Electronic Publication: 2023 Dec 11.
Typ publikacji:: Randomized Controlled Trial; Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Brain*
Receptor-Interacting Protein Serine-Threonine Kinases*
Adult ; Humans ; Healthy Volunteers ; Dose-Response Relationship, Drug ; Area Under Curve ; Half-Life ; Double-Blind Method

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Skocz do pozycji: 14.

Tytuł:: Overexpression of microRNA-205-5p promotes cholangiocarcinoma growth by reducing expression of homeodomain-interacting protein kinase 3.
Autorzy:: Mon AM; Medical Technology Program, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, 40002, Thailand.; Cholangiocarcinoma Research Institute, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand.
Intuyod K; Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand.; Cholangiocarcinoma Research Institute, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand.
Klungsaeng S; Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand.; Cholangiocarcinoma Research Institute, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand.
Jusakul A; Centre for Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, 40002, Thailand.; Cholangiocarcinoma Research Institute, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand.
Pongking T; Biomedical Sciences Program, Graduate School, Khon Kaen University, Khon Kaen, 40002, Thailand.; Cholangiocarcinoma Research Institute, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand.
Lert-Itthiporn W; Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand.; Cholangiocarcinoma Research Institute, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand.
Luvira V; Department of Surgery, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand.; Cholangiocarcinoma Research Institute, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand.
Pairojkul C; Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand.; Cholangiocarcinoma Research Institute, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand.
Plengsuriyakarn T; Graduate Program in Bioclinical Sciences, Center of Excellence in Pharmacology and Molecular Biology of Malaria and Cholangiocarcinoma, Chulabhorn International College of Medicine, Thammasat University (Rangsit Campus), Pathum Thani, 12120, Thailand.
Na-Bangchang K; Graduate Program in Bioclinical Sciences, Center of Excellence in Pharmacology and Molecular Biology of Malaria and Cholangiocarcinoma, Chulabhorn International College of Medicine, Thammasat University (Rangsit Campus), Pathum Thani, 12120, Thailand.
Pinlaor S; Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand.; Cholangiocarcinoma Research Institute, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand.
Pinlaor P; Centre for Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, 40002, Thailand. .; Cholangiocarcinoma Research Institute, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Dec 17; Vol. 13 (1), pp. 22444. Date of Electronic Publication: 2023 Dec 17.
Typ publikacji:: Journal Article
MeSH Terms:: Bile Duct Neoplasms*/pathology
Cholangiocarcinoma*/pathology
MicroRNAs*/genetics
MicroRNAs*/metabolism
Protein Serine-Threonine Kinases*/genetics
Humans ; Bile Ducts, Intrahepatic/pathology ; Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation/genetics ; Gene Expression Regulation, Neoplastic

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Skocz do pozycji: 15.

Tytuł:: In silico identification and biological evaluation of a selective MAP4K4 inhibitor against pancreatic cancer.
Autorzy:: Chang CD; Ph.D. Program in Drug Discovery and Development Industry, College of Pharmacy, Taipei Medical University, Taipei, Taiwan.
Chao MW; School of Medicine, College of Medicine, National Sun Yat-sen University, Kaohsiung, Taiwan.; Institute of Biopharmaceutical Sciences, College of Medicine, National Sun Yat-sen University, Kaohsiung, Taiwan.
Lee HY; Ph.D. Program in Drug Discovery and Development Industry, College of Pharmacy, Taipei Medical University, Taipei, Taiwan.; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, Taiwan.; TMU Research Center of Cancer Translational Medicine, Taipei Medical University, Taipei, Taiwan.
Liu YT; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, Taiwan.
Tu HJ; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan.
Lien ST; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan.
Lin TE; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan.; Ph.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan.
Sung TY; Biomedical Translation Research Center, Academia Sinica, Taipei, Taiwan.
Yen SC; Warshel Institute for Computational Biology, The Chinese University of Hong Kong (Shenzhen), Shenzhen, Guangdong, People's Republic of China.
Huang SH; Graphen Inc, New York, NY, USA.
Hsu KC; Ph.D. Program in Drug Discovery and Development Industry, College of Pharmacy, Taipei Medical University, Taipei, Taiwan.; TMU Research Center of Cancer Translational Medicine, Taipei Medical University, Taipei, Taiwan.; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan.; Ph.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan.; TMU Research Center for Drug Discovery, Taipei Medical University, Taipei, Taiwan.; Cancer Center, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan.
Pan SL; Ph.D. Program in Drug Discovery and Development Industry, College of Pharmacy, Taipei Medical University, Taipei, Taiwan.; TMU Research Center of Cancer Translational Medicine, Taipei Medical University, Taipei, Taiwan.; Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan.; Ph.D. Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan.; TMU Research Center for Drug Discovery, Taipei Medical University, Taipei, Taiwan.; Pokaż więcej
Źródło:: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 2166039.
Typ publikacji:: Journal Article
MeSH Terms:: Pancreatic Neoplasms*/enzymology
Protein Serine-Threonine Kinases*/antagonists & inhibitors
Protein Kinase Inhibitors*/chemistry
Protein Kinase Inhibitors*/pharmacology
Antineoplastic Agents*/chemistry
Antineoplastic Agents*/pharmacology
Humans ; Cell Line, Tumor ; Gemcitabine/chemistry ; Gemcitabine/pharmacology ; Intracellular Signaling Peptides and Proteins ; Computer Simulation ; Pancreatic Neoplasms

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Skocz do pozycji: 16.

Tytuł:: Fine-tuning of MPK6/3 phosphorylation by a lectin receptor-like kinase LecRK-VIII.2 regulates seed development.
Autorzy:: Xiao W; College of Biology, Hunan University, Changsha, China.
Hu S; Hainan Key Laboratory for Biosafety Monitoring and Molecular Breeding in Off-Season Reproduction Regions, Institute of Tropical Bioscience and Biotechnology & San Ya Research Institute, Chinese Academy of Tropical Agricultural Sciences, Haikou, China.; State Key Laboratory of Tropical Crop Breeding, Chinese Academy of Tropical Agricultural Sciences, Sanya, China.
Yu K; College of Biology, Hunan University, Changsha, China.
Li Y; College of Biology, Hunan University, Changsha, China.
Cai R; College of Biology, Hunan University, Changsha, China.
Xie D; College of Biology, Hunan University, Changsha, China.
Zhou H; College of Biology, Hunan University, Changsha, China.
Guo Z; College of Biology, Hunan University, Changsha, China.
Liu S; College of Biology, Hunan University, Changsha, China.
Zou X; College of Biology, Hunan University, Changsha, China.
Ye S; College of Bioscience and Biotechnology, Hunan Agricultural University, Changsha, China.
Guo A; Hainan Key Laboratory for Biosafety Monitoring and Molecular Breeding in Off-Season Reproduction Regions, Institute of Tropical Bioscience and Biotechnology & San Ya Research Institute, Chinese Academy of Tropical Agricultural Sciences, Haikou, China.; State Key Laboratory of Tropical Crop Breeding, Chinese Academy of Tropical Agricultural Sciences, Sanya, China.
Yao R; College of Biology, Hunan University, Changsha, China.
Zhao H; Hainan Key Laboratory for Biosafety Monitoring and Molecular Breeding in Off-Season Reproduction Regions, Institute of Tropical Bioscience and Biotechnology & San Ya Research Institute, Chinese Academy of Tropical Agricultural Sciences, Haikou, China.; State Key Laboratory of Tropical Crop Breeding, Chinese Academy of Tropical Agricultural Sciences, Sanya, China.
Guo X; College of Biology, Hunan University, Changsha, China.; Pokaż więcej
Źródło:: Plant biotechnology journal [Plant Biotechnol J] 2023 Dec; Vol. 21 (12), pp. 2414-2416. Date of Electronic Publication: 2023 Oct 03.
Typ publikacji:: Journal Article
MeSH Terms:: Protein Serine-Threonine Kinases*/genetics
Arabidopsis Proteins*/genetics
Arabidopsis Proteins*/metabolism
Phosphorylation ; Seeds/genetics ; Seeds/metabolism ; Lectins ; Gene Expression Regulation, Plant/genetics

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Skocz do pozycji: 17.

Tytuł:: Recent progress in discovery of novel AAK1 inhibitors: from pain therapy to potential anti-viral agents.
Autorzy:: Yuan YH; School of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines; Engineering Laboratory of Development and Application of Traditional Chinese Medicines; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou, Zhejiang, China.
Mao ND; School of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines; Engineering Laboratory of Development and Application of Traditional Chinese Medicines; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou, Zhejiang, China.
Duan JL; School of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines; Engineering Laboratory of Development and Application of Traditional Chinese Medicines; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou, Zhejiang, China.
Zhang H; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines; Engineering Laboratory of Development and Application of Traditional Chinese Medicines; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou, Zhejiang, China.; School of Basic Medical Science, Hangzhou Normal University, Hangzhou, China.
Garrido C; INSERM UMR 1231, Labex LipSTIC, University of Bourgogne, Dijon, France.; Cancer Center George François Leclerc, Dijon, France.; University of Bourgogne Franche-Comté, Besançon, France.
Lirussi F; INSERM UMR 1231, Labex LipSTIC, University of Bourgogne, Dijon, France.; University of Franche-Comté & University Hospital of Besançon, Besancon, France.
Gao Y; School of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines; Engineering Laboratory of Development and Application of Traditional Chinese Medicines; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou, Zhejiang, China.; Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Xie T; School of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines; Engineering Laboratory of Development and Application of Traditional Chinese Medicines; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou, Zhejiang, China.
Ye XY; School of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang, China.; Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines; Engineering Laboratory of Development and Application of Traditional Chinese Medicines; Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou, Zhejiang, China.; Pokaż więcej
Źródło:: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 2279906. Date of Electronic Publication: 2023 Nov 13.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Protein Serine-Threonine Kinases*
Antiviral Agents*/pharmacology
Humans ; Phosphorylation ; Pain

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Skocz do pozycji: 18.

Tytuł:: Identification of a new structural family of SGK1 inhibitors as potential neuroprotective agents.
Autorzy:: Maestro I; Centro de Investigaciones, Biológicas Margarita Salas-CSIC, Madrid, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.
Madruga E; Centro de Investigaciones, Biológicas Margarita Salas-CSIC, Madrid, Spain.
Boya P; Centro de Investigaciones, Biológicas Margarita Salas-CSIC, Madrid, Spain.
Martínez A; Centro de Investigaciones, Biológicas Margarita Salas-CSIC, Madrid, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain.; Pokaż więcej
Źródło:: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 2153841.
Typ publikacji:: Journal Article
MeSH Terms:: Neuroprotective Agents*/pharmacology
Protein Serine-Threonine Kinases*/antagonists & inhibitors
Apoptosis

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Skocz do pozycji: 19.

Tytuł:: Antifibrotic Effect of Selenium-Containing Nanoparticles on a Model of TAA-Induced Liver Fibrosis.
Autorzy:: Varlamova EG; Institute of Cell Biophysics, the Russian Academy of Sciences, Federal Research Center 'Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences', 142290 Pushchino, Russia.
Goltyaev MV; Institute of Cell Biophysics, the Russian Academy of Sciences, Federal Research Center 'Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences', 142290 Pushchino, Russia.
Rogachev VV; Institute of Cell Biophysics, the Russian Academy of Sciences, Federal Research Center 'Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences', 142290 Pushchino, Russia.
Gudkov SV; Prokhorov General Physics Institute, the Russian Academy of Sciences, 119991 Moscow, Russia.; Department of Biophysics, Lobachevsky State University of Nizhny Novgorod, 603022 Nizhny Novgorod, Russia.
Karaduleva EV; Institute of Cell Biophysics, the Russian Academy of Sciences, Federal Research Center 'Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences', 142290 Pushchino, Russia.
Turovsky EA; Institute of Cell Biophysics, the Russian Academy of Sciences, Federal Research Center 'Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences', 142290 Pushchino, Russia.; Pokaż więcej
Źródło:: Cells [Cells] 2023 Nov 28; Vol. 12 (23). Date of Electronic Publication: 2023 Nov 28.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Protein Serine-Threonine Kinases*/metabolism
Selenium*/pharmacology
Selenium*/therapeutic use
Humans ; Sorafenib/pharmacology ; Sorafenib/therapeutic use ; Thioacetamide/adverse effects ; Endoribonucleases/metabolism ; Liver Cirrhosis/chemically induced ; Liver Cirrhosis/drug therapy

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Skocz do pozycji: 20.

Tytuł:: Dynamic Regulation of brsk2 in the Social and Motor Development of Zebrafish: A Developmental Behavior Analysis.
Autorzy:: Deng J; Division of Child Health Care, Children's Hospital of Fudan University, National Children's Medical Center, 399 Wanyuan Road, Shanghai 201102, China.
Liu C; Division of Child Health Care, Children's Hospital of Fudan University, National Children's Medical Center, 399 Wanyuan Road, Shanghai 201102, China.
Hu M; Division of Child Health Care, Children's Hospital of Fudan University, National Children's Medical Center, 399 Wanyuan Road, Shanghai 201102, China.
Hu C; Division of Child Health Care, Children's Hospital of Fudan University, National Children's Medical Center, 399 Wanyuan Road, Shanghai 201102, China.
Lin J; Center for Translational Medicine, Institute of Pediatrics, Shanghai Key Laboratory of Birth Defect, Children's Hospital of Fudan University, National Children's Medical Center, 399 Wanyuan Road, Shanghai 201102, China.
Li Q; Center for Translational Medicine, Institute of Pediatrics, Shanghai Key Laboratory of Birth Defect, Children's Hospital of Fudan University, National Children's Medical Center, 399 Wanyuan Road, Shanghai 201102, China.
Xu X; Division of Child Health Care, Children's Hospital of Fudan University, National Children's Medical Center, 399 Wanyuan Road, Shanghai 201102, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Nov 19; Vol. 24 (22). Date of Electronic Publication: 2023 Nov 19.
Typ publikacji:: Journal Article
MeSH Terms:: Zebrafish*/growth & development
Zebrafish*/metabolism
Protein Serine-Threonine Kinases*/metabolism
Animals ; Humans ; Behavior, Animal ; Locomotion ; Mutation ; Social Behavior

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