Temat: "Proteins." - OpacWWW

Skocz do pozycji: 1.

Tytuł:: SKN-1/NRF2 upregulation by vitamin A is conserved from nematodes to mammals and is critical for lifespan extension in Caenorhabditis elegans.
Autorzy:: Sirakawin C; Laboratory of Molecular Neurobiology, Sheng Yushou Center of Cell Biology and Immunology, Department of Genetics and Developmental Biology, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China.
Lin D; Laboratory of Molecular Neurobiology, Sheng Yushou Center of Cell Biology and Immunology, Department of Genetics and Developmental Biology, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China.; Key Laboratory for Molecular Enzymology and Engineering, School of Life Sciences, Jilin University, Changchun, China.
Zhou Z; Laboratory of Molecular Neurobiology, Sheng Yushou Center of Cell Biology and Immunology, Department of Genetics and Developmental Biology, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China.
Wang X; Shanghai Key Laboratory of Pancreatic Diseases, Institute of Translational Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Kelleher R; University of Warwick, School of Life Sciences, Coventry, UK.
Huang S; Laboratory of Molecular Neurobiology, Sheng Yushou Center of Cell Biology and Immunology, Department of Genetics and Developmental Biology, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China.
Long W; Laboratory of Molecular Neurobiology, Sheng Yushou Center of Cell Biology and Immunology, Department of Genetics and Developmental Biology, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China.
Pires-daSilva A; University of Warwick, School of Life Sciences, Coventry, UK.
Liu Y; Laboratory of Molecular Neurobiology, Sheng Yushou Center of Cell Biology and Immunology, Department of Genetics and Developmental Biology, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China.
Wang J; Shanghai Key Laboratory of Pancreatic Diseases, Institute of Translational Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Vinnikov IA; Laboratory of Molecular Neurobiology, Sheng Yushou Center of Cell Biology and Immunology, Department of Genetics and Developmental Biology, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China.; Pokaż więcej
Źródło:: Aging cell [Aging Cell] 2024 Mar; Vol. 23 (3), pp. e14064. Date of Electronic Publication: 2023 Dec 15.
Typ publikacji:: Journal Article
MeSH Terms:: Caenorhabditis elegans*/metabolism
Caenorhabditis elegans Proteins*/metabolism
Animals ; Humans ; Mice ; Longevity/genetics ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/metabolism ; Vitamin A/pharmacology ; Vitamin A/metabolism ; NF-E2-Related Factor 2/metabolism ; Up-Regulation ; Oxidative Stress ; Mammals/metabolism ; Micronutrients/metabolism ; Micronutrients/pharmacology

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Skocz do pozycji: 2.

Tytuł:: Engineering and application of LacI mutants with stringent expressions.
Autorzy:: Wu J; CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China.
Liang C; CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Li Y; CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China.
Zeng Y; School of Life Sciences, Hebei University, Baoding, China.
Sun X; Beijing Key Laboratory of Plant Resources Research and Development, Beijing Technology and Business University, Beijing, China.
Jiang P; CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Chen W; CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Xiong D; CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China.
Jin JM; Beijing Key Laboratory of Plant Resources Research and Development, Beijing Technology and Business University, Beijing, China.
Tang SY; CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.; Pokaż więcej
Źródło:: Microbial biotechnology [Microb Biotechnol] 2024 Mar; Vol. 17 (3), pp. e14427.
Typ publikacji:: Journal Article
MeSH Terms:: Escherichia coli*/genetics
Escherichia coli*/metabolism
Escherichia coli Proteins*/genetics
Escherichia coli Proteins*/metabolism
Lac Repressors/genetics ; Lac Repressors/chemistry ; Lac Repressors/metabolism ; Mutation ; Promoter Regions, Genetic ; Bacterial Proteins/genetics

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Skocz do pozycji: 3.

Tytuł:: Abalone peptide increases stress resilience and cost-free longevity via SKN-1-governed transcriptional metabolic reprogramming in C. elegans.
Autorzy:: Wang Q; Institute for Food Nutrition and Human Health, School of Food Science and Engineering, South China University of Technology, Guangzhou, China.; Guangdong Province Key Laboratory for Biocosmetics, Guangzhou, China.
Wang L; Institute for Food Nutrition and Human Health, School of Food Science and Engineering, South China University of Technology, Guangzhou, China.; Center for Bioresources and Drug Discovery, School of Biosciences and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou, China.
Huang Z; Institute for Food Nutrition and Human Health, School of Food Science and Engineering, South China University of Technology, Guangzhou, China.; Center for Bioresources and Drug Discovery, School of Biosciences and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou, China.
Xiao Y; Institute for Food Nutrition and Human Health, School of Food Science and Engineering, South China University of Technology, Guangzhou, China.; Guangdong Province Key Laboratory for Biocosmetics, Guangzhou, China.
Liu M; Institute for Food Nutrition and Human Health, School of Food Science and Engineering, South China University of Technology, Guangzhou, China.; Guangdong Province Key Laboratory for Biocosmetics, Guangzhou, China.
Liu H; Institute for Food Nutrition and Human Health, School of Food Science and Engineering, South China University of Technology, Guangzhou, China.; Center for Bioresources and Drug Discovery, School of Biosciences and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou, China.
Yu Y; Research and Development Center, Infinitus (China) Company Ltd, Guangzhou, China.
Liang M; Research and Development Center, Infinitus (China) Company Ltd, Guangzhou, China.
Luo N; Institute of Chinese Medicinal Sciences, Guangdong Pharmaceutical University, Guangzhou, China.
Li K; Institute of Chinese Medicinal Sciences, Guangdong Pharmaceutical University, Guangzhou, China.
Mishra A; European Bioinformatics Institute, Cambridge, UK.
Huang Z; Institute for Food Nutrition and Human Health, School of Food Science and Engineering, South China University of Technology, Guangzhou, China.; Guangdong Province Key Laboratory for Biocosmetics, Guangzhou, China.; Center for Bioresources and Drug Discovery, School of Biosciences and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou, China.; Pokaż więcej
Źródło:: Aging cell [Aging Cell] 2024 Feb; Vol. 23 (2), pp. e14046. Date of Electronic Publication: 2023 Nov 22.
Typ publikacji:: Journal Article
MeSH Terms:: Caenorhabditis elegans Proteins*/genetics
Caenorhabditis elegans Proteins*/metabolism
Frailty*
Resilience, Psychological*
Animals ; Caenorhabditis elegans/metabolism ; DNA-Binding Proteins/metabolism ; Longevity/genetics ; Metabolic Reprogramming ; Oxidative Stress/genetics ; Paraquat/toxicity ; Peptides/metabolism

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Skocz do pozycji: 4.

Tytuł:: Releasing YAP dysfunction-caused replicative toxicity rejuvenates mesenchymal stem cells.
Autorzy:: Yu F; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.; Department of Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Yao L; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.; Department of Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Li F; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Wang C; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.; Department of Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Ye L; State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.; Department of Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, China.; Pokaż więcej
Źródło:: Aging cell [Aging Cell] 2023 Sep; Vol. 22 (9), pp. e13913. Date of Electronic Publication: 2023 Jun 20.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Mesenchymal Stem Cells*
YAP-Signaling Proteins*
Humans ; Cell Cycle Proteins/genetics ; Genomic Instability ; Phosphorylation

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Skocz do pozycji: 5.

Tytuł:: Sensing preferences for prokaryotic solute binding protein families.
Autorzy:: Cerna-Vargas JP; Department of Biotechnology and Environmental Protection, Estación Experimental del Zaidín, Consejo Superior de Investigaciones Científicas, Granada, Spain.; Centro de Biotecnología y Genómica de Plantas CBGP, Universidad Politécnica de Madrid-Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria/CSIC, Parque Científico y Tecnológico de la UPM, Madrid, Spain.
Sánchez-Romera B; Scientific Instrumentation Service, Estación Experimental del Zaidín, Consejo Superior de Investigaciones Científicas, Granada, Spain.
Matilla MA; Department of Biotechnology and Environmental Protection, Estación Experimental del Zaidín, Consejo Superior de Investigaciones Científicas, Granada, Spain.
Ortega Á; Department of Biochemistry and Molecular Biology B and Immunology, Faculty of Chemistry, University of Murcia, Murcia, Spain.
Krell T; Department of Biotechnology and Environmental Protection, Estación Experimental del Zaidín, Consejo Superior de Investigaciones Científicas, Granada, Spain.; Pokaż więcej
Źródło:: Microbial biotechnology [Microb Biotechnol] 2023 Sep; Vol. 16 (9), pp. 1823-1833. Date of Electronic Publication: 2023 Aug 07.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Prokaryotic Cells*/metabolism
Membrane Transport Proteins*/metabolism
Ligands ; Phylogeny ; Biological Evolution ; Bacterial Proteins/metabolism ; Protein Binding

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Skocz do pozycji: 6.

Tytuł:: Surface layer proteins in species of the family Lactobacillaceae.
Autorzy:: Palomino MM; Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina.; Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales (IQUIBICEN), CONICET- Universidad de Buenos Aires, Buenos Aires, Argentina.
Allievi MC; Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina.; Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales (IQUIBICEN), CONICET- Universidad de Buenos Aires, Buenos Aires, Argentina.
Gordillo TB; Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina.; Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales (IQUIBICEN), CONICET- Universidad de Buenos Aires, Buenos Aires, Argentina.
Bockor SS; Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina.; Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales (IQUIBICEN), CONICET- Universidad de Buenos Aires, Buenos Aires, Argentina.
Fina Martin J; Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales (IQUIBICEN), CONICET- Universidad de Buenos Aires, Buenos Aires, Argentina.
Ruzal SM; Departamento de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina.; Instituto de Química Biológica de la Facultad de Ciencias Exactas y Naturales (IQUIBICEN), CONICET- Universidad de Buenos Aires, Buenos Aires, Argentina.; Pokaż więcej
Źródło:: Microbial biotechnology [Microb Biotechnol] 2023 Jun; Vol. 16 (6), pp. 1232-1249. Date of Electronic Publication: 2023 Feb 08.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Bacterial Proteins*/metabolism
Membrane Glycoproteins*/chemistry
Membrane Glycoproteins*/genetics
Membrane Proteins/metabolism ; Lactobacillaceae/metabolism

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Skocz do pozycji: 7.

Tytuł:: Transcriptional activation of Jun and Fos members of the AP-1 complex is a conserved signature of immune aging that contributes to inflammaging.
Autorzy:: Karakaslar EO; The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut, USA.; Leiden University Medical Center (LUMC), Leiden, The Netherlands.
Katiyar N; The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut, USA.
Hasham M; The Jackson Laboratory for Mammalian Genetics, Bar Harbor, Maine, USA.
Youn A; Sanofi, Bridgewater, New Jersey, USA.
Sharma S; The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut, USA.
Chung CH; The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut, USA.
Marches R; The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut, USA.
Korstanje R; The Jackson Laboratory for Mammalian Genetics, Bar Harbor, Maine, USA.
Banchereau J; The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut, USA.; Immunai, New York, New York, USA.
Ucar D; The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut, USA.; Department of Genetics and Genome Sciences, University of Connecticut Health Center, Farmington, Connecticut, USA.; Pokaż więcej
Źródło:: Aging cell [Aging Cell] 2023 Apr; Vol. 22 (4), pp. e13792. Date of Electronic Publication: 2023 Feb 24.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Proto-Oncogene Proteins c-fos*/genetics
Proto-Oncogene Proteins c-fos*/metabolism
Transcription Factor AP-1*/genetics
Transcription Factor AP-1*/metabolism
Animals ; Humans ; Mice ; Aging/genetics ; Interleukin-6/metabolism ; Mice, Inbred C57BL ; Proto-Oncogene Proteins c-jun/genetics ; Proto-Oncogene Proteins c-jun/metabolism ; Transcriptional Activation

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Skocz do pozycji: 8.

Tytuł:: The conserved microRNA-229 family controls low-insulin signaling and dietary restriction induced longevity through interactions with SKN-1/NRF2.
Autorzy:: Matai L; HMS Initiative for RNA Medicine, Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Stathis T; Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, Connecticut, USA.
Lee JD; HMS Initiative for RNA Medicine, Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Parsons C; Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, Connecticut, USA.
Saxena T; HMS Initiative for RNA Medicine, Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Shlomchik K; Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, Connecticut, USA.
Slack FJ; HMS Initiative for RNA Medicine, Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.; Pokaż więcej
Źródło:: Aging cell [Aging Cell] 2023 Apr; Vol. 22 (4), pp. e13785. Date of Electronic Publication: 2023 Feb 07.
Typ publikacji:: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
MeSH Terms:: MicroRNAs*/genetics
MicroRNAs*/metabolism
Caenorhabditis elegans Proteins*/genetics
Caenorhabditis elegans Proteins*/metabolism
Animals ; Caenorhabditis elegans/metabolism ; Longevity ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/metabolism ; NF-E2-Related Factor 2/metabolism ; Insulin/metabolism ; Forkhead Transcription Factors/metabolism ; Transcription Factors/genetics ; Transcription Factors/metabolism

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Skocz do pozycji: 9.

Tytuł:: SATB2, coordinated with CUX1, regulates IL-1β-induced senescence-like phenotype in endothelial cells by fine-tuning the atherosclerosis-associated p16 expression.
Autorzy:: Wu T; Department of Cardiovascular Medicine, Xiangya Hospital, Central South University, Changsha, Hunan, China.; Aging Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Wu Y; Aging Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.; Department of Medicine, Xiangya School of Medicine, Central South University, Changsha, Hunan, China.
Jiang D; Aging Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Sun W; Center for Pulmonary Vascular Biology and Medicine, Pittsburgh Heart, Lung, Blood, and Vascular Medicine Institute, University of Pittsburgh School of Medicine and University of Pittsburgh Medical Center, Pennsylvania, Pittsburgh, USA.
Zou M; Aging Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Vasamsetti SB; Center for Pulmonary Vascular Biology and Medicine, Pittsburgh Heart, Lung, Blood, and Vascular Medicine Institute, University of Pittsburgh School of Medicine and University of Pittsburgh Medical Center, Pennsylvania, Pittsburgh, USA.
Dutta P; Center for Pulmonary Vascular Biology and Medicine, Pittsburgh Heart, Lung, Blood, and Vascular Medicine Institute, University of Pittsburgh School of Medicine and University of Pittsburgh Medical Center, Pennsylvania, Pittsburgh, USA.
Leers SA; UPMC Vascular Laboratories, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Di W; Department of Periodontology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Li G; Aging Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.; Department of Medicine, Division of Cardiology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.; Pokaż więcej
Źródło:: Aging cell [Aging Cell] 2023 Feb; Vol. 22 (2), pp. e13765. Date of Electronic Publication: 2023 Jan 12.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Atherosclerosis*/genetics
Matrix Attachment Region Binding Proteins*/genetics
Humans ; Cellular Senescence/genetics ; Cyclin-Dependent Kinase Inhibitor p16/genetics ; Cyclin-Dependent Kinase Inhibitor p16/metabolism ; Endothelial Cells/metabolism ; Genome-Wide Association Study ; Homeodomain Proteins/genetics ; Phenotype ; Repressor Proteins/genetics ; Transcription Factors/genetics ; Interferon beta-1b/pharmacology

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Skocz do pozycji: 10.

Tytuł:: Exercise enhancement by RGS14 disruption is mediated by brown adipose tissue.
Autorzy:: Vatner DE; Department of Medicine, Rutgers, New Jersey Medical School, Newark, New Jersey, USA.
Oydanich M; Department of Cell Biology and Molecular Medicine, Rutgers, New Jersey Medical School, Newark, New Jersey, USA.
Zhang J; Department of Cell Biology and Molecular Medicine, Rutgers, New Jersey Medical School, Newark, New Jersey, USA.
Campbell SC; Department of Kinesiology and Health, Rutgers University New Brunswick, New Brunswick, New Jersey, USA.
Vatner SF; Department of Cell Biology and Molecular Medicine, Rutgers, New Jersey Medical School, Newark, New Jersey, USA.; Pokaż więcej
Źródło:: Aging cell [Aging Cell] 2023 Apr; Vol. 22 (4), pp. e13791. Date of Electronic Publication: 2023 Mar 10.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Adipose Tissue, Brown*/metabolism
RGS Proteins*/genetics
RGS Proteins*/metabolism
Animals ; Mice ; Aging ; GTP-Binding Proteins/metabolism ; Longevity/genetics ; Mice, Inbred C57BL ; Mice, Knockout ; Signal Transduction

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Skocz do pozycji: 11.

Tytuł:: Endosomal trafficking protein TBC-2 modulates stress resistance and lifespan through DAF-16-dependent and independent mechanisms.
Autorzy:: Traa A; Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada.; Metabolic Disorders and Complications Program, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.; Brain Repair and Integrative Neuroscience Program, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.
Soo SK; Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada.; Metabolic Disorders and Complications Program, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.; Brain Repair and Integrative Neuroscience Program, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.
AlOkda A; Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada.; Metabolic Disorders and Complications Program, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.; Brain Repair and Integrative Neuroscience Program, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.
Ko B; Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada.; Metabolic Disorders and Complications Program, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.; Brain Repair and Integrative Neuroscience Program, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.
Rocheleau CE; Metabolic Disorders and Complications Program, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.; Division of Experimental Medicine, Department of Medicine, McGill University, Montreal, Quebec, Canada.
Van Raamsdonk JM; Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada.; Metabolic Disorders and Complications Program, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.; Brain Repair and Integrative Neuroscience Program, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.; Division of Experimental Medicine, Department of Medicine, McGill University, Montreal, Quebec, Canada.; Pokaż więcej
Źródło:: Aging cell [Aging Cell] 2023 Mar; Vol. 22 (3), pp. e13762. Date of Electronic Publication: 2023 Feb 15.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:: Longevity*/genetics
Caenorhabditis elegans Proteins*/genetics
Caenorhabditis elegans Proteins*/metabolism
Animals ; Caenorhabditis elegans/metabolism ; Transcription Factors/metabolism ; Insulin/metabolism ; Forkhead Transcription Factors/genetics ; Forkhead Transcription Factors/metabolism ; GTPase-Activating Proteins/metabolism

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Skocz do pozycji: 12.

Tytuł:: Small G protein RAC-2 regulates forgetting via the JNK-1 signalling pathway in Caenorhabditis elegans.
Autorzy:: Bai H; School of Medicine, and State Key Laboratory for Conservation and Utilization of Bio-Resources, Yunnan University, Kunming, China.; College of Public Health, Kunming Medical University, Kunming, China.
Huang H; School of Medicine, and State Key Laboratory for Conservation and Utilization of Bio-Resources, Yunnan University, Kunming, China.
Zhao N; Neurosurgery of the Second Hospital affiliated with Kunming Medical University, Kunming, China.
Gu H; School of Medicine, and State Key Laboratory for Conservation and Utilization of Bio-Resources, Yunnan University, Kunming, China.
Li Y; School of Medicine, and State Key Laboratory for Conservation and Utilization of Bio-Resources, Yunnan University, Kunming, China.
Zou W; College of Public Health, Kunming Medical University, Kunming, China.
Wu T; Neurosurgery of the Second Hospital affiliated with Kunming Medical University, Kunming, China.
Huang X; School of Medicine, and State Key Laboratory for Conservation and Utilization of Bio-Resources, Yunnan University, Kunming, China.; Pokaż więcej
Źródło:: The European journal of neuroscience [Eur J Neurosci] 2022 Dec; Vol. 56 (12), pp. 6162-6173. Date of Electronic Publication: 2022 Nov 22.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Caenorhabditis elegans*/genetics
Caenorhabditis elegans*/metabolism
Caenorhabditis elegans Proteins*/genetics
Animals ; MAP Kinase Signaling System ; rho GTP-Binding Proteins/metabolism ; Signal Transduction/physiology ; Mitogen-Activated Protein Kinases/metabolism

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Skocz do pozycji: 13.

Tytuł:: The protein scaffold calibrates metal specificity and activation in MerR sensors.
Autorzy:: Mendoza JI; Instituto de Biología Molecular y Celular de Rosario (IBR), Universidad Nacional de Rosario (UNR)-Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Rosario, Argentina.
Lescano J; Instituto de Biología Molecular y Celular de Rosario (IBR), Universidad Nacional de Rosario (UNR)-Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Rosario, Argentina.
Soncini FC; Instituto de Biología Molecular y Celular de Rosario (IBR), Universidad Nacional de Rosario (UNR)-Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Rosario, Argentina.; Departamento de Microbiología, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Rosario, Argentina.
Checa SK; Instituto de Biología Molecular y Celular de Rosario (IBR), Universidad Nacional de Rosario (UNR)-Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Rosario, Argentina.; Departamento de Microbiología, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Rosario, Argentina.; Pokaż więcej
Źródło:: Microbial biotechnology [Microb Biotechnol] 2022 Dec; Vol. 15 (12), pp. 2992-3002. Date of Electronic Publication: 2022 Sep 22.
Typ publikacji:: Journal Article
MeSH Terms:: DNA-Binding Proteins*/chemistry
DNA-Binding Proteins*/genetics
DNA-Binding Proteins*/metabolism
Mercury*/metabolism
Bacterial Proteins/metabolism ; Metals/metabolism ; Promoter Regions, Genetic

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Skocz do pozycji: 14.

Tytuł:: Mitochondrial S-adenosylmethionine deficiency induces mitochondrial unfolded protein response and extends lifespan in Caenorhabditis elegans.
Autorzy:: Chen TY; Institute of Biopharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Wang FY; Institute of Biochemistry and Molecular Biology, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Lee PJ; Institute of Biopharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Hsu AL; Institute of Biochemistry and Molecular Biology, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Department of Biological Science & Technology and Institute of Biochemistry and Molecular Biology, China Medical University, Taichung, Taiwan.; Department of Internal Medicine, Division of Geriatric and Palliative Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Ching TT; Institute of Biopharmaceutical Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Pokaż więcej
Źródło:: Aging cell [Aging Cell] 2024 Apr; Vol. 23 (4), pp. e14103. Date of Electronic Publication: 2024 Feb 15.
Typ publikacji:: Journal Article
MeSH Terms:: Caenorhabditis elegans*/metabolism
Caenorhabditis elegans Proteins*/genetics
Caenorhabditis elegans Proteins*/metabolism
Animals ; Longevity/genetics ; S-Adenosylmethionine/metabolism ; Mitochondria/metabolism ; Unfolded Protein Response ; RNA, Transfer/metabolism

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Skocz do pozycji: 15.

Tytuł:: The SATB1-MIR22-GBA axis mediates glucocerebroside accumulation inducing a cellular senescence-like phenotype in dopaminergic neurons.
Autorzy:: Russo T; Department of Neurobiology and Behavior, Stony Brook University, Stony Brook, New York, USA.; Center for Nervous System Disorders, Stony Brook University, Stony Brook, New York, USA.
Kolisnyk B; Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, New York, USA.
B S A; Department of Neurobiology and Behavior, Stony Brook University, Stony Brook, New York, USA.; Center for Nervous System Disorders, Stony Brook University, Stony Brook, New York, USA.
Plessis-Belair J; Department of Neurobiology and Behavior, Stony Brook University, Stony Brook, New York, USA.; Center for Nervous System Disorders, Stony Brook University, Stony Brook, New York, USA.
Kim TW; Center for Stem Cell Biology, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.; Developmental Biology Program, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
Martin J; Department of Neurobiology and Behavior, Stony Brook University, Stony Brook, New York, USA.; Center for Nervous System Disorders, Stony Brook University, Stony Brook, New York, USA.
Ni J; Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, New York, USA.
Pearson JA; Medical Scientist Training Program, Stony Brook University Renaissance School of Medicine, Stony Brook University, Stony Brook, New York, USA.
Park EJ; Stem Cells and Regenerative Medicine, Center for Cell and Gene Therapy, Department of Molecular and Cellular Biology and Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, Texas, USA.
Sher RB; Department of Neurobiology and Behavior, Stony Brook University, Stony Brook, New York, USA.; Center for Nervous System Disorders, Stony Brook University, Stony Brook, New York, USA.
Studer L; Center for Stem Cell Biology, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.; Developmental Biology Program, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
Riessland M; Department of Neurobiology and Behavior, Stony Brook University, Stony Brook, New York, USA.; Center for Nervous System Disorders, Stony Brook University, Stony Brook, New York, USA.; Pokaż więcej
Źródło:: Aging cell [Aging Cell] 2024 Apr; Vol. 23 (4), pp. e14077. Date of Electronic Publication: 2024 Feb 01.
Typ publikacji:: Journal Article
MeSH Terms:: Matrix Attachment Region Binding Proteins*/genetics
Matrix Attachment Region Binding Proteins*/metabolism
Parkinson Disease*/genetics
Parkinson Disease*/metabolism
MicroRNAs*/genetics
MicroRNAs*/metabolism
Humans ; Mice ; Animals ; Dopaminergic Neurons/metabolism ; Glucosylceramides/metabolism ; Gliosis ; Neuroinflammatory Diseases ; Cellular Senescence/genetics ; Transcription Factors/metabolism ; Phenotype

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Skocz do pozycji: 16.

Tytuł:: Systemic intracellular analysis for balancing complex biosynthesis in a transcriptionally deregulated Escherichia coli l-Methionine producer.
Autorzy:: Harting C; University of Stuttgart, Stuttgart, Germany.
Teleki A; University of Stuttgart, Stuttgart, Germany.
Braakmann M; University of Stuttgart, Stuttgart, Germany.
Jankowitsch F; Evonik Operations GmbH, Halle-Künsebeck, Germany.
Takors R; University of Stuttgart, Stuttgart, Germany.; Pokaż więcej
Źródło:: Microbial biotechnology [Microb Biotechnol] 2024 Mar; Vol. 17 (3), pp. e14433.
Typ publikacji:: Journal Article
MeSH Terms:: Escherichia coli*/genetics
Escherichia coli*/metabolism
Escherichia coli Proteins*/genetics
Escherichia coli Proteins*/metabolism
Methionine/metabolism ; Racemethionine ; Fermentation

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Skocz do pozycji: 17.

Tytuł:: Single-worm quantitative proteomics reveals aging heterogeneity in isogenic Caenorhabditis elegans.
Autorzy:: Zhu TY; Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China.; Cancer Center, Zhejiang University, Hangzhou, China.
Li ST; Glbizzia Biosciences Co., Ltd, Beijing, China.
Liu DD; Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China.; Cancer Center, Zhejiang University, Hangzhou, China.
Zhang X; Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China.; Cancer Center, Zhejiang University, Hangzhou, China.
Zhou L; Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China.; Cancer Center, Zhejiang University, Hangzhou, China.
Zhou R; Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.
Yang B; Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China.; Cancer Center, Zhejiang University, Hangzhou, China.; Pokaż więcej
Źródło:: Aging cell [Aging Cell] 2024 Mar; Vol. 23 (3), pp. e14055. Date of Electronic Publication: 2023 Dec 03.
Typ publikacji:: Journal Article
MeSH Terms:: Caenorhabditis elegans*/genetics
Caenorhabditis elegans*/metabolism
Caenorhabditis elegans Proteins*/genetics
Caenorhabditis elegans Proteins*/metabolism
Animals ; Mice ; Humans ; Proteomics/methods ; Aging ; Disease Models, Animal

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Skocz do pozycji: 18.

Tytuł:: High plasma concentrations of acyl-coenzyme A binding protein (ACBP) predispose to cardiovascular disease: Evidence for a phylogenetically conserved proaging function of ACBP.
Autorzy:: Montégut L; Centre de Recherche des Cordeliers, Equipe labellisée par la Ligue contre le cancer, Inserm U1138, Université Paris Cité, Sorbonne Université, Paris, France.; Metabolomics and Cell Biology Platforms, Gustave Roussy Institut, Villejuif, France.; Faculté de Médecine, Université de Paris Saclay, Paris, France.
Joseph A; Centre de Recherche des Cordeliers, Equipe labellisée par la Ligue contre le cancer, Inserm U1138, Université Paris Cité, Sorbonne Université, Paris, France.; Metabolomics and Cell Biology Platforms, Gustave Roussy Institut, Villejuif, France.; Faculté de Médecine, Université de Paris Saclay, Paris, France.; Service de médecine intensive réanimation, Hôpital Saint-Louis, Paris, France.
Chen H; Centre de Recherche des Cordeliers, Equipe labellisée par la Ligue contre le cancer, Inserm U1138, Université Paris Cité, Sorbonne Université, Paris, France.; Metabolomics and Cell Biology Platforms, Gustave Roussy Institut, Villejuif, France.; Faculté de Médecine, Université de Paris Saclay, Paris, France.
Abdellatif M; Centre de Recherche des Cordeliers, Equipe labellisée par la Ligue contre le cancer, Inserm U1138, Université Paris Cité, Sorbonne Université, Paris, France.; Metabolomics and Cell Biology Platforms, Gustave Roussy Institut, Villejuif, France.; Department of Cardiology, Medical University of Graz, Graz, Austria.; BioTechMed-Graz, Graz, Austria.
Ruckenstuhl C; Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria.
Motiño O; Centre de Recherche des Cordeliers, Equipe labellisée par la Ligue contre le cancer, Inserm U1138, Université Paris Cité, Sorbonne Université, Paris, France.; Metabolomics and Cell Biology Platforms, Gustave Roussy Institut, Villejuif, France.
Lambertucci F; Centre de Recherche des Cordeliers, Equipe labellisée par la Ligue contre le cancer, Inserm U1138, Université Paris Cité, Sorbonne Université, Paris, France.; Metabolomics and Cell Biology Platforms, Gustave Roussy Institut, Villejuif, France.
Anagnostopoulos G; Centre de Recherche des Cordeliers, Equipe labellisée par la Ligue contre le cancer, Inserm U1138, Université Paris Cité, Sorbonne Université, Paris, France.; Metabolomics and Cell Biology Platforms, Gustave Roussy Institut, Villejuif, France.; Faculté de Médecine, Université de Paris Saclay, Paris, France.
Lachkar S; Centre de Recherche des Cordeliers, Equipe labellisée par la Ligue contre le cancer, Inserm U1138, Université Paris Cité, Sorbonne Université, Paris, France.; Metabolomics and Cell Biology Platforms, Gustave Roussy Institut, Villejuif, France.
Dichtinger S; Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria.
Maiuri MC; Centre de Recherche des Cordeliers, Equipe labellisée par la Ligue contre le cancer, Inserm U1138, Université Paris Cité, Sorbonne Université, Paris, France.; Metabolomics and Cell Biology Platforms, Gustave Roussy Institut, Villejuif, France.
Goldwasser F; Department of Medical Oncology, Cochin Hospital, AP-HP, Paris, France.; URP4466, Université Paris Cité, Paris, France.
Blanchet B; Pharmacokinetics and Pharmacochemistry Unit, Cochin Hospital, Paris Descartes University, CARPEM, AP-HP, Paris, France.; UMR8038 CNRS, U1268 INSERM, Faculty of Pharmacy, University of Paris, PRES Sorbonne Paris Cité, CARPEM, Paris, France.
Fumeron F; Institut Necker-Enfants Malades, Université Paris Cité, INSERM UMR-S1151, CNRS UMR-S8253, Paris, France.
Martins I; Centre de Recherche des Cordeliers, Equipe labellisée par la Ligue contre le cancer, Inserm U1138, Université Paris Cité, Sorbonne Université, Paris, France.; Metabolomics and Cell Biology Platforms, Gustave Roussy Institut, Villejuif, France.
Madeo F; BioTechMed-Graz, Graz, Austria.; Institute of Molecular Biosciences, NAWI Graz, University of Graz, Graz, Austria.; Field of Excellence BioHealth, University of Graz, Graz, Austria.
Kroemer G; Centre de Recherche des Cordeliers, Equipe labellisée par la Ligue contre le cancer, Inserm U1138, Université Paris Cité, Sorbonne Université, Paris, France.; Metabolomics and Cell Biology Platforms, Gustave Roussy Institut, Villejuif, France.; Institut du Cancer Paris CARPEM, Department of Biology, Hôpital Européen Georges Pompidou, AP-HP, Paris, France.; Pokaż więcej
Źródło:: Aging cell [Aging Cell] 2023 Jan; Vol. 22 (1), pp. e13751. Date of Electronic Publication: 2022 Dec 12.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cardiovascular Diseases*/genetics
Carrier Proteins*
Animals ; Humans ; Mice ; Coenzyme A/metabolism ; Diazepam Binding Inhibitor/genetics ; Diazepam Binding Inhibitor/metabolism ; Nuclear Proteins/metabolism

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Skocz do pozycji: 19.

Tytuł:: FBXO31 sensitizes cancer stem cells-like cells to cisplatin by promoting ferroptosis and facilitating proteasomal degradation of GPX4 in cholangiocarcinoma.
Autorzy:: Zhu Z; Department of Hepatobiliary Surgery, The Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Zheng Y; Department of Hepatobiliary Surgery, The Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
He H; Clinical Research Center, The Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Yang L; Department of Hepatobiliary Surgery, The Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Yang J; Institution of Plastic Surgery, The Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Li M; Department of Hepatobiliary Surgery, The Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Dai W; Department of Hepatobiliary Surgery, The Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Huang H; Department of Hepatobiliary Surgery, The Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.; Institution of Plastic Surgery, The Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.; Pokaż więcej
Źródło:: Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2022 Dec; Vol. 42 (12), pp. 2871-2888. Date of Electronic Publication: 2022 Nov 01.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Bile Duct Neoplasms*/pathology
Cholangiocarcinoma*/pathology
F-Box Proteins*/metabolism
Ferroptosis*
Phospholipid Hydroperoxide Glutathione Peroxidase*/metabolism
Humans ; Bile Ducts, Intrahepatic/pathology ; Cell Line, Tumor ; Cisplatin/pharmacology ; Neoplasm Recurrence, Local/pathology ; Neoplastic Stem Cells/pathology ; Tumor Suppressor Proteins/metabolism

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Skocz do pozycji: 20.

Tytuł:: Engineering Saccharomyces cerevisiae-based biosensors for copper detection.
Autorzy:: Fan C; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Fujian, China.
Zhang D; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Fujian, China.
Mo Q; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Fujian, China.
Yuan J; State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Fujian, China.; Pokaż więcej
Źródło:: Microbial biotechnology [Microb Biotechnol] 2022 Nov; Vol. 15 (11), pp. 2854-2860. Date of Electronic Publication: 2022 Jul 13.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Saccharomyces cerevisiae Proteins*/genetics
Biosensing Techniques*/methods
Saccharomyces cerevisiae/genetics ; Copper ; Transcription Factors/genetics ; Betaxanthins ; Repressor Proteins ; Galactose/genetics

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