Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Wyszukujesz frazę ""Proto-Oncogene Proteins c-akt"" wg kryterium: Temat


Tytuł:
Egg white-derived peptide KPHAEVVLR promotes wound healing in rat palatal mucosa via PI3K/AKT/mTOR pathway.
Autorzy:
Zhang H; Department of Oral Implantology, Hospital of Stomatology, Jilin University, Changchun 130021, China; Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, Hospital of Stomatology, Jilin University, Changchun 130021, China.
Chen S; Department of Oral Implantology, Hospital of Stomatology, Jilin University, Changchun 130021, China; Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, Hospital of Stomatology, Jilin University, Changchun 130021, China.
Yan X; School of life Sciences, Jilin University, Changchun 130021, China.
Zhang M; Department of Oral Implantology, Hospital of Stomatology, Jilin University, Changchun 130021, China.
Jiang Y; School of life Sciences, Jilin University, Changchun 130021, China. Electronic address: .
Zhou Y; Department of Oral Implantology, Hospital of Stomatology, Jilin University, Changchun 130021, China; Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, Hospital of Stomatology, Jilin University, Changchun 130021, China. Electronic address: .
Pokaż więcej
Źródło:
Peptides [Peptides] 2023 Oct; Vol. 168, pp. 171074. Date of Electronic Publication: 2023 Aug 03.
Typ publikacji:
Journal Article
MeSH Terms:
Phosphatidylinositol 3-Kinases*/genetics
Phosphatidylinositol 3-Kinases*/metabolism
Proto-Oncogene Proteins c-akt*/genetics
Proto-Oncogene Proteins c-akt*/metabolism
Animals ; Humans ; Rats ; Cell Movement ; Cell Proliferation ; Egg White ; Mucous Membrane/metabolism ; Peptides/pharmacology ; TOR Serine-Threonine Kinases/genetics ; TOR Serine-Threonine Kinases/metabolism ; Wound Healing
Czasopismo naukowe
Tytuł:
Edaravone promotes viability of random skin flaps via activating PI3K/Akt/mTOR signalling pathway-mediated enhancement of autophagy.
Autorzy:
Bi M; Department of Plastic Surgery, Lanzhou University Second Hospital, Lanzhou, China.
Qin Y; Department of Plastic Surgery, Lanzhou University Second Hospital, Lanzhou, China.
Zhao L; Cuiying Biomedical Research Center, Lanzhou, China.
Zhang X; Department of Plastic Surgery, Lanzhou University Second Hospital, Lanzhou, China.
Pokaż więcej
Źródło:
International wound journal [Int Wound J] 2023 Oct; Vol. 20 (8), pp. 3088-3104. Date of Electronic Publication: 2023 Apr 11.
Typ publikacji:
Journal Article
MeSH Terms:
Proto-Oncogene Proteins c-akt*/metabolism
Proto-Oncogene Proteins c-akt*/pharmacology
Phosphatidylinositol 3-Kinases*/metabolism
Phosphatidylinositol 3-Kinases*/pharmacology
Mice ; Animals ; Edaravone/metabolism ; Edaravone/pharmacology ; Endothelial Cells ; TOR Serine-Threonine Kinases/genetics ; TOR Serine-Threonine Kinases/metabolism ; TOR Serine-Threonine Kinases/pharmacology ; Autophagy
Czasopismo naukowe
Tytuł:
TSPAN8 regulates EGFR/AKT pathway to enhance metastasis in gastric cancer.
Autorzy:
Zhang L; Department of Pathology, Xuzhou Medical University, Xuzhou, 221004, China.; Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, 221004, China.
Xu Y; Department of Pathology, Xuzhou Medical University, Xuzhou, 221004, China.
Cai E; Department of Pathology, Xuzhou Medical University, Xuzhou, 221004, China.
Zheng M; Department of Pathology, Xuzhou Medical University, Xuzhou, 221004, China.
Liu L; Department of Physiology, Xuzhou Medical University, Xuzhou, 221004, China.
Wang Q; Department of Pathology, Xuzhou Medical University, Xuzhou, 221004, China. .
Li S; Department of Laboratory Medicine, Affiliated Hospital of Xuzhou Medical University, Xuzhou, 221002, China. .
Pokaż więcej
Źródło:
Molecular biology reports [Mol Biol Rep] 2023 Oct; Vol. 50 (10), pp. 7955-7965. Date of Electronic Publication: 2023 Aug 03.
Typ publikacji:
Journal Article
MeSH Terms:
Proto-Oncogene Proteins c-akt*/genetics
Proto-Oncogene Proteins c-akt*/metabolism
Stomach Neoplasms*/metabolism
Animals ; Mice ; Humans ; Signal Transduction ; Mice, Nude ; Cell Line, Tumor ; ErbB Receptors/genetics ; ErbB Receptors/metabolism ; Cell Movement/genetics ; Cell Proliferation ; Gene Expression Regulation, Neoplastic/genetics ; Neoplasm Invasiveness ; Tetraspanins/genetics ; Tetraspanins/metabolism
Czasopismo naukowe
Tytuł:
MiR-222-3p suppresses C2C12 myoblast proliferation and differentiation via the inhibition of IRS-1/PI3K/Akt pathway.
Autorzy:
Wei X; College of Veterinary Medicine, Shanxi Agricultural University, Jinzhong, Shanxi, P.R. China.
Wang J; Department of Nephrology, Shanghai General Hosptial, Shanghai Jiaotong University School of Medicine, Shanghai, P.R. China.
Sun Y; College of Veterinary Medicine, Shanxi Agricultural University, Jinzhong, Shanxi, P.R. China.
Zhao T; College of Veterinary Medicine, Shanxi Agricultural University, Jinzhong, Shanxi, P.R. China.
Luo X; College of Veterinary Medicine, Shanxi Agricultural University, Jinzhong, Shanxi, P.R. China.
Lu J; College of Veterinary Medicine, Shanxi Agricultural University, Jinzhong, Shanxi, P.R. China.
Hou W; College of Veterinary Medicine, Shanxi Agricultural University, Jinzhong, Shanxi, P.R. China.
Yu X; College of Veterinary Medicine, Shanxi Agricultural University, Jinzhong, Shanxi, P.R. China.
Xue L; College of Veterinary Medicine, Shanxi Agricultural University, Jinzhong, Shanxi, P.R. China.
Yan Y; College of Veterinary Medicine, Shanxi Agricultural University, Jinzhong, Shanxi, P.R. China.
Wang H; College of Veterinary Medicine, Shanxi Agricultural University, Jinzhong, Shanxi, P.R. China.
Pokaż więcej
Źródło:
Journal of cellular biochemistry [J Cell Biochem] 2023 Sep; Vol. 124 (9), pp. 1379-1390. Date of Electronic Publication: 2023 Aug 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
MicroRNAs*/metabolism
Proto-Oncogene Proteins c-akt*/genetics
Proto-Oncogene Proteins c-akt*/metabolism
Animals ; Mice ; Cell Differentiation/genetics ; Cell Proliferation/genetics ; Insulin Receptor Substrate Proteins/genetics ; Insulin Receptor Substrate Proteins/metabolism ; Muscle Development/genetics ; Myoblasts/metabolism ; Phosphatidylinositol 3-Kinase/metabolism ; Phosphatidylinositol 3-Kinases/genetics ; Phosphatidylinositol 3-Kinases/metabolism
Czasopismo naukowe
Tytuł:
P300 increases CSNK2A1 expression which accelerates colorectal cancer progression through activation of the PI3K-AKT-mTOR axis.
Autorzy:
Liu J; Tumor Surgical Department, Beijing Chuiyangliu Hospital, No.2, Chuiyangliu South Street, Chaoyang District, Beijing, 100022, China. Electronic address: .
Pokaż więcej
Źródło:
Experimental cell research [Exp Cell Res] 2023 Sep 01; Vol. 430 (1), pp. 113694. Date of Electronic Publication: 2023 Jun 28.
Typ publikacji:
Journal Article
MeSH Terms:
Colorectal Neoplasms*/pathology
Proto-Oncogene Proteins c-akt*/genetics
Proto-Oncogene Proteins c-akt*/metabolism
Humans ; Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation/genetics ; Gene Expression Regulation, Neoplastic ; Phosphatidylinositol 3-Kinases/genetics ; Phosphatidylinositol 3-Kinases/metabolism ; Signal Transduction ; TOR Serine-Threonine Kinases/genetics ; TOR Serine-Threonine Kinases/metabolism
Czasopismo naukowe
Tytuł:
Investigating the synergistic potential of TRAIL and SAHA in inducing apoptosis in MOLT-4 cancer cells.
Autorzy:
Mohammad Mirzapour M; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; Hematology and Oncology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. Electronic address: .
Farshdousti Hagh M; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; Hematology and Oncology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. Electronic address: .
Marofi F; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; Hematology and Oncology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. Electronic address: .
Solali S; Hematology and Oncology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. Electronic address: .
Alaei A; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; Hematology and Oncology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. Electronic address: .
Pokaż więcej
Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2023 Oct 08; Vol. 676, pp. 13-20. Date of Electronic Publication: 2023 Jul 04.
Typ publikacji:
Journal Article
MeSH Terms:
Proto-Oncogene Proteins c-akt*
Neoplasms*
Humans ; Apoptosis ; Cell Line ; Flow Cytometry ; NF-kappa B ; Phosphatidylinositol 3-Kinases
Czasopismo naukowe
Tytuł:
Sanhuang decoction inhibits autophagy of periodontal ligament fibroblasts during orthodontic tooth movement by activating PI3K-Akt-mTOR pathway.
Autorzy:
Yang Y; Department of Orthodontics, Stomatological Hospital, General Hospital of Ningxia Medical University, Yinchuan 750004, PR China.
Liu Q; Department of Prosthodontics, Yinchuan Stomatological Hospital, Yinchuan 750004, PR China.
Lu X; Department of Orthodontics, Stomatological Hospital, General Hospital of Ningxia Medical University, Yinchuan 750004, PR China.
Ma J; Department of Orthodontics, Stomatological Hospital, General Hospital of Ningxia Medical University, Yinchuan 750004, PR China.
Mei D; Department of Orthodontics, Stomatological Hospital, General Hospital of Ningxia Medical University, Yinchuan 750004, PR China.
Chen Q; Department of Orthodontics, Stomatological Hospital, General Hospital of Ningxia Medical University, Yinchuan 750004, PR China.
Zhao T; Department of Orthodontics, Stomatological Hospital, General Hospital of Ningxia Medical University, Yinchuan 750004, PR China.
Chen J; Department of Orthodontics, Stomatological Hospital, General Hospital of Ningxia Medical University, Yinchuan 750004, PR China. Electronic address: .
Pokaż więcej
Źródło:
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2023 Oct; Vol. 166, pp. 115391. Date of Electronic Publication: 2023 Sep 06.
Typ publikacji:
Journal Article
MeSH Terms:
Phosphatidylinositol 3-Kinases*
Proto-Oncogene Proteins c-akt*
Animals ; Rats ; Periodontal Ligament ; Reactive Oxygen Species ; Tooth Movement Techniques ; Autophagy ; Fibroblasts ; TOR Serine-Threonine Kinases
Czasopismo naukowe
Tytuł:
Cytochrome b561 regulates iron metabolism by activating the Akt/mTOR pathway to promote Breast Cancer Cells proliferation.
Autorzy:
Zhou X; Research Center for High Altitude Medicine, Qinghai University, Key Laboratory of High Altitude Medicine (Ministry of Education), Key Laboratory of Application and Foundation for High Altitude Medicine Research in Qinghai Province (Qinghai-Utah Joint Research Key Lab for High Altitude Medicine), Laboratory for High Altitude Medicine of Qinghai Province, Xining, 810001, China; Pathology Department, Affiliated Hospital of Qinghai University, Xining, 810001, China.
Guo X; Pathology Department, Affiliated Hospital of Qinghai University, Xining, 810001, China.
Han J; Pathology Department, Affiliated Hospital of Qinghai University, Xining, 810001, China.
Wang M; Research Center for High Altitude Medicine, Qinghai University, Key Laboratory of High Altitude Medicine (Ministry of Education), Key Laboratory of Application and Foundation for High Altitude Medicine Research in Qinghai Province (Qinghai-Utah Joint Research Key Lab for High Altitude Medicine), Laboratory for High Altitude Medicine of Qinghai Province, Xining, 810001, China; Breast Disease Diagnosis and Treatment Center, Affiliated Hospital of Qinghai University, Xining, 810001, China.
Liu Z; Research Center for High Altitude Medicine, Qinghai University, Key Laboratory of High Altitude Medicine (Ministry of Education), Key Laboratory of Application and Foundation for High Altitude Medicine Research in Qinghai Province (Qinghai-Utah Joint Research Key Lab for High Altitude Medicine), Laboratory for High Altitude Medicine of Qinghai Province, Xining, 810001, China; Breast Disease Diagnosis and Treatment Center, Affiliated Hospital of Qinghai University, Xining, 810001, China.
Ren D; Breast Disease Diagnosis and Treatment Center, Affiliated Hospital of Qinghai University, Xining, 810001, China.
Zhao J; Research Center for High Altitude Medicine, Qinghai University, Key Laboratory of High Altitude Medicine (Ministry of Education), Key Laboratory of Application and Foundation for High Altitude Medicine Research in Qinghai Province (Qinghai-Utah Joint Research Key Lab for High Altitude Medicine), Laboratory for High Altitude Medicine of Qinghai Province, Xining, 810001, China; Breast Disease Diagnosis and Treatment Center, Affiliated Hospital of Qinghai University, Xining, 810001, China. Electronic address: .
Li Z; Research Center for High Altitude Medicine, Qinghai University, Key Laboratory of High Altitude Medicine (Ministry of Education), Key Laboratory of Application and Foundation for High Altitude Medicine Research in Qinghai Province (Qinghai-Utah Joint Research Key Lab for High Altitude Medicine), Laboratory for High Altitude Medicine of Qinghai Province, Xining, 810001, China; Department of Hematopathology, Affiliated Hospital of Qinghai University, Xining, 810001, China. Electronic address: .
Pokaż więcej
Źródło:
Experimental cell research [Exp Cell Res] 2023 Oct 01; Vol. 431 (1), pp. 113760. Date of Electronic Publication: 2023 Aug 26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Proto-Oncogene Proteins c-akt*/genetics
Breast Neoplasms*/genetics
Female ; Humans ; Apoferritins ; TOR Serine-Threonine Kinases/genetics ; Iron
Czasopismo naukowe
Tytuł:
Allyl isothiocyanate inhibits cell migration and invasion in human gastric cancer AGS cells via affecting PI3K/AKT and MAPK signaling pathway in vitro.
Autorzy:
Lin TS; Department of Pharmacy, Saint Mary's Hospital Luodong, Luodong, Yilan, Taiwan.; Department of Nursing, Saint Mary's Junior College of Medicine, Nursing and Management, Sanxing, Yilan, Taiwan.
Huang WN; Department of Biological Science and Technology, China Medical University, Taichung, Taiwan.
Yang JL; Department of Nursing, Saint Mary's Junior College of Medicine, Nursing and Management, Sanxing, Yilan, Taiwan.
Peng SF; Department of Biological Science and Technology, China Medical University, Taichung, Taiwan.; Department of Medical Research, China Medical University Hospital, Taichung, Taiwan.
Liu KC; Department of Medical Laboratory Science and Biotechnology, China Medical University, Taichung, Taiwan.
Chen JC; Department of Medicinal Botanicals and Foods on Health Applications, Da-Yeh University, Changhua, Taiwan.
Hsia TC; Department of Respiratory Therapy, China Medical University, Taichung, Taiwan.; Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan.
Huang AC; Department of Nursing, Saint Mary's Junior College of Medicine, Nursing and Management, Sanxing, Yilan, Taiwan.
Pokaż więcej
Źródło:
Environmental toxicology [Environ Toxicol] 2023 Oct; Vol. 38 (10), pp. 2287-2297. Date of Electronic Publication: 2023 Jun 15.
Typ publikacji:
Journal Article
MeSH Terms:
Proto-Oncogene Proteins c-akt*/metabolism
Stomach Neoplasms*/metabolism
Humans ; Phosphatidylinositol 3-Kinases/metabolism ; Signal Transduction ; Cell Movement ; Cell Line, Tumor ; Neoplasm Invasiveness ; Cell Proliferation
Czasopismo naukowe
Tytuł:
Regulation of B-1 cell numbers and B cell-mediated antibody production by Inpp4b.
Autorzy:
Xu M; Department of Pathogenic Biology and Immunology, Jiangsu Key Laboratory of Immunity and Metabolism, Xuzhou Medical University, Xuzhou, China.; National Experimental Demonstration Center for Basic Medicine Education, Xuzhou Medical University, Xuzhou, China.; Clinical Laboratory Center, The First Hospital of Putian City, Putian, China.
Ren J; Department of Pathogenic Biology and Immunology, Jiangsu Key Laboratory of Immunity and Metabolism, Xuzhou Medical University, Xuzhou, China.; National Experimental Demonstration Center for Basic Medicine Education, Xuzhou Medical University, Xuzhou, China.
Jia W; Department of dermatology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Wang S; Department of Pathogenic Biology and Immunology, Jiangsu Key Laboratory of Immunity and Metabolism, Xuzhou Medical University, Xuzhou, China.; National Experimental Demonstration Center for Basic Medicine Education, Xuzhou Medical University, Xuzhou, China.
Liu Y; Department of Pathogenic Biology and Immunology, Jiangsu Key Laboratory of Immunity and Metabolism, Xuzhou Medical University, Xuzhou, China.; National Experimental Demonstration Center for Basic Medicine Education, Xuzhou Medical University, Xuzhou, China.
Chen X; Department of Pathogenic Biology and Immunology, Jiangsu Key Laboratory of Immunity and Metabolism, Xuzhou Medical University, Xuzhou, China.; National Experimental Demonstration Center for Basic Medicine Education, Xuzhou Medical University, Xuzhou, China.
Shi J; Central Laboratory, Hebei Collaborative Innovation Center of Tumor Microecological Metabolism Regulation, Hebei Key Laboratory of Cancer Radiotherapy and Chemotherapy, Affiliated Hospital of Hebei University, Baoding, China.
Wang H; Department of Pathogenic Biology and Immunology, Jiangsu Key Laboratory of Immunity and Metabolism, Xuzhou Medical University, Xuzhou, China.; National Experimental Demonstration Center for Basic Medicine Education, Xuzhou Medical University, Xuzhou, China.
Pokaż więcej
Źródło:
Scandinavian journal of immunology [Scand J Immunol] 2023 Oct; Vol. 98 (4), pp. e13309. Date of Electronic Publication: 2023 Jun 30.
Typ publikacji:
Journal Article
MeSH Terms:
Proto-Oncogene Proteins c-akt*/metabolism
B-Lymphocyte Subsets*
Humans ; Mice ; Animals ; Antibody Formation ; Phosphoric Monoester Hydrolases/genetics ; Phosphoric Monoester Hydrolases/metabolism ; Antigens ; Phosphatidylinositols ; Cell Count
Czasopismo naukowe
Tytuł:
IGF-1 Combined with OPN Promotes Neuronal Axon Growth in Vitro Through the IGF-1R/Akt/mTOR Signaling Pathway in Lipid Rafts.
Autorzy:
Zhao Q; Department of Rehabilitation Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Su H; Department of Rehabilitation Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Jiang W; Department of Rehabilitation Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Luo H; Department of Rehabilitation Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Pan L; Department of Rehabilitation Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Liu Y; State Key Laboratory of Trauma, Burn and Combined Injury, Research Institute of Surgery, Daping Hospital, Army Medical University, Chongqing, China.
Yang C; State Key Laboratory of Trauma, Burn and Combined Injury, Research Institute of Surgery, Daping Hospital, Army Medical University, Chongqing, China.
Yin Y; Department of Rehabilitation Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Yu L; Department of Rehabilitation Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China. .
Tan B; Department of Rehabilitation Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China. .
Pokaż więcej
Źródło:
Neurochemical research [Neurochem Res] 2023 Oct; Vol. 48 (10), pp. 3190-3201. Date of Electronic Publication: 2023 Jul 03.
Typ publikacji:
Journal Article
MeSH Terms:
Insulin-Like Growth Factor I*/pharmacology
Proto-Oncogene Proteins c-akt*/metabolism
Axons/metabolism ; Membrane Microdomains/metabolism ; Neurons/metabolism ; Osteopontin ; Phosphatidylinositol 3-Kinases/metabolism ; Phosphorylation ; Receptor, IGF Type 1/metabolism ; Signal Transduction ; Sirolimus/pharmacology ; TOR Serine-Threonine Kinases/metabolism ; Animals ; Rats
Czasopismo naukowe
Tytuł:
NAT10 promotes osteogenic differentiation of periodontal ligament stem cells by regulating VEGFA-mediated PI3K/AKT signaling pathway through ac4C modification.
Autorzy:
Cui Z; Pediatric Surgery, Children's Hospital of Changchun, Changchun, 130021, Jilin Province, People's Republic of China.
Xu Y; Department of Stomatology, The First Hospital of Jilin University, Changchun, 130021, Jilin Province, People's Republic of China.
Wu P; Pediatric Surgery, Children's Hospital of Changchun, Changchun, 130021, Jilin Province, People's Republic of China.
Lu Y; Pediatric Surgery, Children's Hospital of Changchun, Changchun, 130021, Jilin Province, People's Republic of China.
Tao Y; Pediatric Surgery, Children's Hospital of Changchun, Changchun, 130021, Jilin Province, People's Republic of China.
Zhou C; Pediatric Surgery, Children's Hospital of Changchun, Changchun, 130021, Jilin Province, People's Republic of China.
Cui R; Pediatric Surgery, Children's Hospital of Changchun, Changchun, 130021, Jilin Province, People's Republic of China.
Li J; Pediatric Surgery, Children's Hospital of Changchun, Changchun, 130021, Jilin Province, People's Republic of China.
Han R; Pediatric Surgery, Children's Hospital of Changchun, No. 1321, Beian Road, Chaoyang District, Changchun, 130021, Jilin Province, People's Republic of China. .
Pokaż więcej
Źródło:
Odontology [Odontology] 2023 Oct; Vol. 111 (4), pp. 870-882. Date of Electronic Publication: 2023 Mar 06.
Typ publikacji:
Journal Article
MeSH Terms:
Periodontal Ligament*
Proto-Oncogene Proteins c-akt*/pharmacology
Humans ; Osteogenesis/genetics ; Vascular Endothelial Growth Factor A ; Phosphatidylinositol 3-Kinases ; Signal Transduction ; Cell Differentiation ; Stem Cells ; Cells, Cultured ; Cell Proliferation ; N-Terminal Acetyltransferases
Czasopismo naukowe
Tytuł:
Effect of SH2B1 on glucose metabolism during pressure overload-induced cardiac hypertrophy and cardiac dysfunction.
Autorzy:
Liu B; Department of Cardiology, Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan, China.; Affiliated Hospital of Hubei University of Chinese Medicine, Wuhan, China.; Hubei Province Academy of Traditional Chinese Medicine, Wuhan, China.
Liu X; Department of Cardiology, Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan, China.; Affiliated Hospital of Hubei University of Chinese Medicine, Wuhan, China.; Hubei Province Academy of Traditional Chinese Medicine, Wuhan, China.
Hu S; Department of Cardiology, Hubei Key Laboratory of Cardiology, Renmin Hospital of Wuhan University, Cardiovascular Research Institute, Wuhan University, Wuhan, China.
Mao S; Department of Cardiology, Hubei Key Laboratory of Cardiology, Renmin Hospital of Wuhan University, Cardiovascular Research Institute, Wuhan University, Wuhan, China.
Yang M; Department of Cardiology, Hubei Key Laboratory of Cardiology, Renmin Hospital of Wuhan University, Cardiovascular Research Institute, Wuhan University, Wuhan, China.
Wu B; Department of Cardiology, Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan, China.; Affiliated Hospital of Hubei University of Chinese Medicine, Wuhan, China.; Hubei Province Academy of Traditional Chinese Medicine, Wuhan, China.
Wu G; Department of Cardiology, Hubei Key Laboratory of Cardiology, Renmin Hospital of Wuhan University, Cardiovascular Research Institute, Wuhan University, Wuhan, China.
Pokaż więcej
Źródło:
Clinical and experimental pharmacology & physiology [Clin Exp Pharmacol Physiol] 2023 Oct; Vol. 50 (10), pp. 815-825. Date of Electronic Publication: 2023 Jul 03.
Typ publikacji:
Journal Article
MeSH Terms:
Proto-Oncogene Proteins c-akt*/metabolism
Phosphatidylinositol 3-Kinases*/metabolism
Humans ; Cardiomegaly/metabolism ; Myocardium/metabolism ; Glucose/metabolism ; RNA, Small Interfering/genetics ; Fatty Acids/metabolism ; Myocytes, Cardiac/metabolism ; Adaptor Proteins, Signal Transducing/metabolism
Czasopismo naukowe
Tytuł:
17-DMAG ameliorates neuroinflammation and BBB disruption via SOX5 mediated PI3K/Akt pathway after intracerebral hemorrhage in rats.
Autorzy:
Hu D; Department of Neurology and Stroke Centre, the First Affiliated Hospital of Jinan University, Guangzhou, China.
Mo X; Department of Oncology, the First Affiliated Hospital of Jinan University, Jinan University, Guangzhou, China.
Luo J; Department of Oncology, the First Affiliated Hospital of Jinan University, Jinan University, Guangzhou, China.
Wang F; Department of Neurology and Stroke Centre, the First Affiliated Hospital of Jinan University, Guangzhou, China.
Huang C; Department of Neurology and Stroke Centre, the First Affiliated Hospital of Jinan University, Guangzhou, China.
Xie H; Department of Neurology and Stroke Centre, the First Affiliated Hospital of Jinan University, Guangzhou, China.
Jin L; Department of Oncology, the First Affiliated Hospital of Jinan University, Jinan University, Guangzhou, China. Electronic address: .
Pokaż więcej
Źródło:
International immunopharmacology [Int Immunopharmacol] 2023 Oct; Vol. 123, pp. 110698. Date of Electronic Publication: 2023 Jul 28.
Typ publikacji:
Journal Article
MeSH Terms:
Blood-Brain Barrier*/drug effects
Blood-Brain Barrier*/metabolism
Cerebral Hemorrhage*/drug therapy
Cerebral Hemorrhage*/metabolism
Proto-Oncogene Proteins c-akt*/metabolism
Animals ; Rats ; Hematoma ; Immunoglobulin G/therapeutic use ; Molecular Docking Simulation ; Neuroinflammatory Diseases ; Phosphatidylinositol 3-Kinases/metabolism ; Rats, Sprague-Dawley ; SOXD Transcription Factors/metabolism
Czasopismo naukowe
Tytuł:
NLRP6 potentiates PI3K/AKT signalling by promoting autophagic degradation of p85α to drive tumorigenesis.
Autorzy:
Zhi F; Department of Neurosurgery, Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, China.
Li B; Department of Neurosurgery, Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, China.
Zhang C; Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.; Medical Research Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China.
Xia F; Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Wang R; Department of Neurosurgery, Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, China.
Xie W; Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Cai S; Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Zhang D; Institute of Bioinformatics and Medical Engineering, School of Electrical and Information Engineering, Jiangsu University of Technology, Changzhou, Jiangsu, China.
Kong R; Institute of Bioinformatics and Medical Engineering, School of Electrical and Information Engineering, Jiangsu University of Technology, Changzhou, Jiangsu, China.
Hu Y; State Key Laboratory of Pharmaceutical Biotechnology, Medical School and School of Life Sciences, Nanjing University, Nanjing, Jiangsu, China.
Yang Y; Department of Neurosurgery, Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, China.
Peng Y; Department of Neurosurgery, Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, China. .
Cui J; Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, MOE Key Laboratory of Gene Function and Regulation, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China. .
Pokaż więcej
Źródło:
Nature communications [Nat Commun] 2023 Sep 28; Vol. 14 (1), pp. 6069. Date of Electronic Publication: 2023 Sep 28.
Typ publikacji:
Journal Article
MeSH Terms:
Proto-Oncogene Proteins c-akt*/metabolism
Phosphatidylinositol 3-Kinases*/metabolism
Humans ; Signal Transduction ; Carcinogenesis ; Autophagy ; Intracellular Signaling Peptides and Proteins/metabolism
Czasopismo naukowe
Tytuł:
FBXW2 suppresses breast tumorigenesis by targeting AKT-Moesin-SKP2 axis.
Autorzy:
Barik GK; Cancer Biology Division, National Centre for Cell Science, Ganeshkhind Road, Pune, Maharashtra, 411007, India.; Department of Biotechnology, Savitribai Phule Pune University, Ganeshkhind Road, Pune, Maharashtra, 411007, India.
Sahay O; Cancer Biology Division, National Centre for Cell Science, Ganeshkhind Road, Pune, Maharashtra, 411007, India.; Department of Biotechnology, Savitribai Phule Pune University, Ganeshkhind Road, Pune, Maharashtra, 411007, India.
Mukhopadhyay A; Saroj Gupta Cancer Centre and Research Institute, Kolkata, West Bengal, 700063, India.
Manne RK; Cancer Biology Division, National Centre for Cell Science, Ganeshkhind Road, Pune, Maharashtra, 411007, India.
Islam S; Cancer Biology Division, National Centre for Cell Science, Ganeshkhind Road, Pune, Maharashtra, 411007, India.
Roy A; Department of Pathology, Nil Ratan Sircar Medical College and Hospital, Kolkata, West Bengal, 700014, India.
Nath S; Saroj Gupta Cancer Centre and Research Institute, Kolkata, West Bengal, 700063, India.; Institute of Health Sciences, Presidency University, New Town, Kolkata, West Bengal, 700156, India.
Santra MK; Cancer Biology Division, National Centre for Cell Science, Ganeshkhind Road, Pune, Maharashtra, 411007, India. .
Pokaż więcej
Źródło:
Cell death & disease [Cell Death Dis] 2023 Sep 22; Vol. 14 (9), pp. 623. Date of Electronic Publication: 2023 Sep 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
F-Box Proteins*/genetics
Proto-Oncogene Proteins c-akt*
Breast Neoplasms*/genetics
Breast Neoplasms*/pathology
Humans ; Cell Transformation, Neoplastic ; Microfilament Proteins ; Oncogenes
Czasopismo naukowe
Tytuł:
Interaction of the AKT and β-catenin signalling pathways and the influence of photobiomodulation on cellular signalling proteins in diabetic wound healing.
Autorzy:
Jere SW; Laser Research Centre, Faculty of Health Sciences, University of Johannesburg, P.O. Box 17011, Doornfontein, 2028, South Africa. .
Abrahamse H; Laser Research Centre, Faculty of Health Sciences, University of Johannesburg, P.O. Box 17011, Doornfontein, 2028, South Africa.
Houreld NN; Laser Research Centre, Faculty of Health Sciences, University of Johannesburg, P.O. Box 17011, Doornfontein, 2028, South Africa.
Pokaż więcej
Źródło:
Journal of biomedical science [J Biomed Sci] 2023 Sep 21; Vol. 30 (1), pp. 81. Date of Electronic Publication: 2023 Sep 21.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Proto-Oncogene Proteins c-akt*/genetics
Diabetes Mellitus*
beta Catenin/genetics ; Signal Transduction ; Protein Serine-Threonine Kinases ; Wound Healing
Czasopismo naukowe
Tytuł:
Experiment-based computational model predicts that IL-6 classic and trans-signaling exhibit similar potency in inducing downstream signaling in endothelial cells.
Autorzy:
Song M; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA. .
Wang Y; Department of Medicine, Augusta University Medical College of Georgia, Augusta, GA, 30912, USA.
Annex BH; Department of Medicine, Augusta University Medical College of Georgia, Augusta, GA, 30912, USA.
Popel AS; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Pokaż więcej
Źródło:
NPJ systems biology and applications [NPJ Syst Biol Appl] 2023 Sep 21; Vol. 9 (1), pp. 45. Date of Electronic Publication: 2023 Sep 21.
Typ publikacji:
Journal Article
MeSH Terms:
Interleukin-6*
Proto-Oncogene Proteins c-akt*
Humans ; Endothelial Cells ; Phosphatidylinositol 3-Kinases ; Cytokines ; Inflammation
Czasopismo naukowe
Tytuł:
Association between intracerebral hemorrhage and cholesterol levels, and molecular mechanism underlying low cholesterol inhibiting autophagy in cerebral arterial smooth muscle cells leading to cell necrosis.
Autorzy:
Tian Z; School of Public Health, Inner Mongolia Medical University, Hohhot, China.
Liu M; School of Public Health, Inner Mongolia Medical University, Hohhot, China.
Zhang Z; School of Basic Medicine, Inner Mongolia Medical University, Hohhot, China.
Yan T; School of Public Health, Inner Mongolia Medical University, Hohhot, China.
Guo S; People's Hospital of Inner Mongolia Autonomous Region, Hohhot, China.
Miao Y; School of Public Health, Inner Mongolia Medical University, Hohhot, China.
Wang J; School of Public Health, Inner Mongolia Medical University, Hohhot, China.
Zhang R; School of Public Health, Inner Mongolia Medical University, Hohhot, China.
Bi Y; School of Public Health, Inner Mongolia Medical University, Hohhot, China.
Zhang N; School of Public Health, Inner Mongolia Medical University, Hohhot, China. Electronic address: .
Zhang X; School of Public Health, Inner Mongolia Medical University, Hohhot, China. Electronic address: .
Pokaż więcej
Źródło:
International journal of cardiology [Int J Cardiol] 2023 Sep 15; Vol. 387, pp. 131134. Date of Electronic Publication: 2023 Jun 22.
Typ publikacji:
Journal Article
MeSH Terms:
Proto-Oncogene Proteins c-akt*/metabolism
Phosphatidylinositol 3-Kinases*/metabolism
Rats ; Animals ; Cross-Sectional Studies ; TOR Serine-Threonine Kinases ; Necrosis ; Cerebral Hemorrhage/genetics ; Autophagy/physiology ; Myocytes, Smooth Muscle/metabolism
Czasopismo naukowe
Tytuł:
Silk Peptide Ameliorates Sarcopenia through the Regulation of Akt/mTOR/FoxO3a Signaling Pathways and the Inhibition of Low-Grade Chronic Inflammation in Aged Mice.
Autorzy:
Oh HJ; Department of Food Science and Biotechnology, College of Life Science, CHA University, Seongnam 13488, Republic of Korea.
Jin H; Department of Food Science and Biotechnology, College of Life Science, CHA University, Seongnam 13488, Republic of Korea.
Lee JY; Worldway Co., Ltd., Sejong 30003, Republic of Korea.
Lee BY; Department of Food Science and Biotechnology, College of Life Science, CHA University, Seongnam 13488, Republic of Korea.
Pokaż więcej
Źródło:
Cells [Cells] 2023 Sep 12; Vol. 12 (18). Date of Electronic Publication: 2023 Sep 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Proto-Oncogene Proteins c-akt*
Sarcopenia*/drug therapy
Humans ; Animals ; Mice ; Aged ; Quality of Life ; TOR Serine-Threonine Kinases ; Inflammation/drug therapy ; Peptides/pharmacology ; Peptides/therapeutic use ; Silk ; Signal Transduction
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies