Temat: "Proto-Oncogene Proteins c-bcl-2" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Epigallocatechin gallate improves neuronal damage in animal model of ischemic stroke and glutamate-exposed neurons via modulation of hippocalcin expression.
Autorzy:: Park DJ; Department of Anatomy, College of Veterinary Medicine, Research Institute of Life Science, Gyeongsang National University, Jinju, South Korea.
Kang JB; Department of Anatomy, College of Veterinary Medicine, Research Institute of Life Science, Gyeongsang National University, Jinju, South Korea.
Koh PO; Department of Anatomy, College of Veterinary Medicine, Research Institute of Life Science, Gyeongsang National University, Jinju, South Korea.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2024 Mar 01; Vol. 19 (3), pp. e0299042. Date of Electronic Publication: 2024 Mar 01 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Catechin*/analogs & derivatives
Ischemic Stroke*/metabolism
Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/therapeutic use
Animals ; Apoptosis ; Calcium/metabolism ; Caspase 3/metabolism ; Glutamic Acid/metabolism ; Hippocalcin/genetics ; Hippocalcin/metabolism ; Infarction, Middle Cerebral Artery/complications ; Infarction, Middle Cerebral Artery/drug therapy ; Neurons/metabolism ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Disease Models, Animal

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Skocz do pozycji: 2.

Tytuł:: Characterizing the consensus residue specificity and surface of BCL-2 binding to BH3 ligands using the Knob-Socket model.
Autorzy:: Yi J; Department of Molecular and Cell Biology, UC Berkeley, Berkeley, California, United States of America.
Kellner V; Department of Chemistry, UC Davis, Davis, California, United States of America.
Joo H; Department of Chemistry, University of the Pacific, Stockton, California, United States of America.
Chien N; Computer Science Department, Stanford University, Stanford, California, United States of America.
Patel S; Department of Chemistry, University of the Pacific, Stockton, California, United States of America.
Chaban Z; Department of Chemistry, University of the Pacific, Stockton, California, United States of America.
Tsai J; Department of Chemistry, University of the Pacific, Stockton, California, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2023 Feb 16; Vol. 18 (2), pp. e0281463. Date of Electronic Publication: 2023 Feb 16 (Print Publication: 2023).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Proto-Oncogene Proteins*/metabolism
Proto-Oncogene Proteins c-bcl-2*/metabolism
Consensus ; Apoptosis Regulatory Proteins/chemistry ; Apoptosis

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Skocz do pozycji: 3.

Tytuł:: Aerobic exercise protects MI heart through miR-133a-3p downregulation of connective tissue growth factor.
Autorzy:: Liu N; College of P.E, Beijing Normal University, Beijing, China.; School of Physical Education, Weinan Normal University, Weinan, Shaanxi, China.
Zhen Z; College of P.E, Beijing Normal University, Beijing, China.
Xiong X; College of P.E, Beijing Normal University, Beijing, China.
Xue Y; College of P.E, Beijing Normal University, Beijing, China.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2024 Jan 25; Vol. 19 (1), pp. e0296430. Date of Electronic Publication: 2024 Jan 25 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: MicroRNAs*/metabolism
Myocardial Infarction*/genetics
Myocardial Infarction*/therapy
Myocardial Infarction*/metabolism
Rats ; Male ; Mice ; Animals ; Caspase 3/metabolism ; Down-Regulation ; bcl-2-Associated X Protein/genetics ; bcl-2-Associated X Protein/metabolism ; Connective Tissue Growth Factor/genetics ; Connective Tissue Growth Factor/metabolism ; Hydrogen Peroxide/metabolism ; Myocytes, Cardiac/metabolism ; Proto-Oncogene Proteins c-bcl-2/genetics ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Apoptosis/genetics

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Skocz do pozycji: 4.

Tytuł:: Clinical trials of R-(-)-gossypol (AT-101) in newly diagnosed and recurrent glioblastoma: NABTT 0602 and NABTT 0702.
Autorzy:: Fiveash JB; Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Ye X; Departments of Neurosurgery and Oncology, Johns Hopkins University, Baltimore, Maryland, United States of America.
Peerboom DM; Cleveland Clinic Brain Tumor and Neuro-Oncology Center, Cleveland, Ohio, United States of America.
Mikkelsen T; Henry Ford Hospital Hermelin Brain Center, Michigan, Indiana, United States of America.
Chowdhary S; Baptist Health, Boca Raton, Florida, United States of America.
Rosenfeld M; University of Pennsylvania Department of Neurology, Philadelphia, Pennsylvania, United States of America.
Lesser GJ; Department of Internal Medicine, Section on Hematology and Oncology, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States of America.
Fisher J; Departments of Neurosurgery and Oncology, Johns Hopkins University, Baltimore, Maryland, United States of America.
Desideri S; Departments of Neurosurgery and Oncology, Johns Hopkins University, Baltimore, Maryland, United States of America.
Grossman S; Departments of Neurosurgery and Oncology, Johns Hopkins University, Baltimore, Maryland, United States of America.
Leopold L; Incyte, Wilmington, Delaware, United States of America.
Nabors LB; Department of Neurology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2024 Jan 29; Vol. 19 (1), pp. e0291128. Date of Electronic Publication: 2024 Jan 29 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Glioblastoma*/pathology
Gossypol*/pharmacology
Gossypol*/therapeutic use
Brain Neoplasms*/pathology
Humans ; Dacarbazine/pharmacology ; Dacarbazine/therapeutic use ; Temozolomide/therapeutic use ; Proto-Oncogene Proteins c-bcl-2 ; Antineoplastic Agents, Alkylating/therapeutic use

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Skocz do pozycji: 5.

Tytuł:: Duhuo Jisheng Decoction regulates intracellular zinc homeostasis by enhancing autophagy via PTEN/Akt/mTOR pathway to improve knee cartilage degeneration.
Autorzy:: Wang YH; Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.; Sichuan Province Orthopedic Hospital, Chengdu, Sichuan, China.
Zhou Y; Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Gao X; Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Sun S; Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Xie YZ; Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Hu YP; Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Fu Y; Chongqing Traditional Chinese Medicine Hospital, Chongqing, China.
Fan XH; Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China.
Xie Q; Sichuan Province Orthopedic Hospital, Chengdu, Sichuan, China.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2024 Jan 02; Vol. 19 (1), pp. e0290925. Date of Electronic Publication: 2024 Jan 02 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Osteoarthritis, Knee*/pathology
Cartilage, Articular*/pathology
Rats ; Animals ; Proto-Oncogene Proteins c-akt/metabolism ; Matrix Metalloproteinase 13/metabolism ; Rats, Sprague-Dawley ; bcl-2-Associated X Protein/metabolism ; Beclin-1/metabolism ; TOR Serine-Threonine Kinases/metabolism ; Chondrocytes/metabolism ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Autophagy ; Homeostasis

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Skocz do pozycji: 6.

Tytuł:: Effect of crocin and treadmill exercise on oxidative stress and heart damage in diabetic rats.
Autorzy:: Pourmousavi L; Department of Physical Education and Sport Sciences, Tabriz Branch, Islamic Azad University, Tabriz, Iran.
Hashemkandi Asadi R; Department of Physical Education and Sport Sciences, Tabriz Branch, Islamic Azad University, Tabriz, Iran.
Zehsaz F; Department of Physical Education and Sport Sciences, Tabriz Branch, Islamic Azad University, Tabriz, Iran.
Jadidi RP; Department of Physical Education and Sport Sciences, Tabriz Branch, Islamic Azad University, Tabriz, Iran.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2023 Dec 19; Vol. 18 (12), pp. e0281692. Date of Electronic Publication: 2023 Dec 19 (Print Publication: 2023).
Typ publikacji:: Journal Article
MeSH Terms:: Diabetes Mellitus, Experimental*/metabolism
Heart Injuries*/complications
Rats ; Animals ; Blood Glucose/metabolism ; Rats, Wistar ; Antioxidants/metabolism ; Oxidative Stress ; Superoxide Dismutase/metabolism ; Proto-Oncogene Proteins c-bcl-2/metabolism

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Skocz do pozycji: 7.

Tytuł:: The power of mumps virus: Matrix protein activates apoptotic pathways in human colorectal cell lines.
Autorzy:: Morovati S; Department of Pathobiology, Division of Biotechnology, School of Veterinary Medicine, Shiraz University, Shiraz, Iran.
Mohammadi A; Department of Pathobiology, Division of Virology, School of Veterinary Medicine, Shiraz University, Shiraz, Iran.
Masoudi R; Department of Pathobiology, Division of Biotechnology, School of Veterinary Medicine, Shiraz University, Shiraz, Iran.
Heidari AA; Department of Clinical Sciences, Division of Aquatic Animal Health and Diseases, School of Veterinary Medicine, Shiraz University, Shiraz, Iran.
Asad Sangabi M; Department of Pathobiology, Division of Virology, School of Veterinary Medicine, Shiraz University, Shiraz, Iran.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2023 Dec 13; Vol. 18 (12), pp. e0295819. Date of Electronic Publication: 2023 Dec 13 (Print Publication: 2023).
Typ publikacji:: Journal Article
MeSH Terms:: Mumps virus*/genetics
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/metabolism
Humans ; Cell Line, Tumor ; Proto-Oncogene Proteins c-bcl-2 ; Apoptosis/genetics

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Skocz do pozycji: 8.

Tytuł:: Cyasterone has a protective effect on steroid-induced Osteonecrosis of the femoral head.
Autorzy:: Sun Y; Department of Sports Medicine, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, Guangdong Province, China.; Lingnan Medical Research Center of Guangzhou University of Chinese Medicine, Guangzhou, 510405, Guangdong Province, China.
Liang M; Department of Obstetrics, Guangdong Women and Chifldren Hospital, Guangzhou, 510010, Guangdong Province, China.
Xing Y; The First Clinical College of Guangzhouf University of Chinese Medicine, Guangzhou, 510405, Guangdong Province, China.
Duan Y; The First Clinical College of Guangzhouf University of Chinese Medicine, Guangzhou, 510405, Guangdong Province, China.
Zhang S; Department of Sports Medicine, Heyuan Hospital of Chinese Medicine, Heyuan, 517000, Guangdong Province, China.
Deng B; Department of Sports Medicine, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, Guangdong Province, China.; Lingnan Medical Research Center of Guangzhou University of Chinese Medicine, Guangzhou, 510405, Guangdong Province, China.
Xiang X; Department of Sports Medicine, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, Guangdong Province, China.; Lingnan Medical Research Center of Guangzhou University of Chinese Medicine, Guangzhou, 510405, Guangdong Province, China.
Zhou B; Department of Sports Medicine, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, Guangdong Province, China.; Lingnan Medical Research Center of Guangzhou University of Chinese Medicine, Guangzhou, 510405, Guangdong Province, China.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2023 Oct 30; Vol. 18 (10), pp. e0293530. Date of Electronic Publication: 2023 Oct 30 (Print Publication: 2023).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Proto-Oncogene Proteins c-akt*/metabolism
Osteonecrosis*/chemically induced
Osteonecrosis*/drug therapy
Osteonecrosis*/prevention & control
Rats ; Animals ; bcl-2-Associated X Protein/metabolism ; Femur Head/pathology ; Cytochromes c/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Tumor Suppressor Protein p53/metabolism ; Proto-Oncogene Proteins c-bcl-2/genetics ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Steroids/metabolism ; Apoptosis ; Dexamethasone/adverse effects ; Dexamethasone/metabolism ; RNA, Messenger/metabolism

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Skocz do pozycji: 9.

Tytuł:: Aged black garlic extract inhibits the growth of estrogen receptor-positive breast cancer cells by downregulating MCL-1 expression through the ROS-JNK pathway.
Autorzy:: Yang Q; Inner Mongolia Medical University Third Clinical Medical College, Inner Mongolia Autonomous Region, Baotou, China.
Li F; Department of Experimental Center, The Third Affiliated Hospital of Inner Mongolia Medical University, Inner Mongolia Autonomous Region, Baotou, China.
Jia G; Department of Laboratory, The Third Affiliated Hospital of Inner Mongolia Medical University, Inner Mongolia Autonomous Region, Baotou, China.
Liu R; Department of General Surgery, The Third Affiliated Hospital of Inner Mongolia Medical University, Inner Mongolia Autonomous Region, Baotou, China.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2023 Jun 23; Vol. 18 (6), pp. e0286454. Date of Electronic Publication: 2023 Jun 23 (Print Publication: 2023).
Typ publikacji:: Journal Article
MeSH Terms:: Breast Neoplasms*/drug therapy
Breast Neoplasms*/pathology
Garlic*
Humans ; Female ; Antioxidants/pharmacology ; MAP Kinase Signaling System ; Reactive Oxygen Species/pharmacology ; Myeloid Cell Leukemia Sequence 1 Protein ; Receptors, Estrogen ; Proto-Oncogene Proteins c-bcl-2 ; Apoptosis ; Plant Extracts/pharmacology ; Plant Extracts/therapeutic use ; Cell Line, Tumor

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Skocz do pozycji: 10.

Tytuł:: Pterostilbene mediates glial and immune responses to alleviate chronic intermittent hypoxia-induced oxidative stress in nerve cells.
Autorzy:: Liu P; Department of Respiratory and Critical Care Medicine, Renmin Hospital of Wuhan University, Wuhan, China.
Zhou P; Department of Respiratory and Critical Care Medicine, Renmin Hospital of Wuhan University, Wuhan, China.
Zhang X; Department of Respiratory and Critical Care Medicine, Renmin Hospital of Wuhan University, Wuhan, China.
Zhao D; Department of Respiratory and Critical Care Medicine, Renmin Hospital of Wuhan University, Wuhan, China.
Chen H; Department of Respiratory and Critical Care Medicine, Renmin Hospital of Wuhan University, Wuhan, China.
Hu K; Department of Respiratory and Critical Care Medicine, Renmin Hospital of Wuhan University, Wuhan, China.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2023 Jun 02; Vol. 18 (6), pp. e0286686. Date of Electronic Publication: 2023 Jun 02 (Print Publication: 2023).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Brain-Derived Neurotrophic Factor*/genetics
Brain-Derived Neurotrophic Factor*/metabolism
Oxidative Stress*
Mice ; Animals ; Hypoxia/metabolism ; Neurons/metabolism ; Superoxide Dismutase/metabolism ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Immunity

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Skocz do pozycji: 11.

Tytuł:: GSK-3β inhibition alleviates arthritis pain via reducing spinal mitochondrial reactive oxygen species level and inflammation.
Autorzy:: Yang HY; School of Pharmacy, Xianning Medical College, Hubei University of Science and Technology, Xianning, China.
Sun X; School of Pharmacy, Xianning Medical College, Hubei University of Science and Technology, Xianning, China.
Zhen SQ; Matang Hospital of Traditional Chinese Medicine, Xianning, China.
Yu LZ; School of Pharmacy, Xianning Medical College, Hubei University of Science and Technology, Xianning, China.
Ding JQ; School of Pharmacy, Xianning Medical College, Hubei University of Science and Technology, Xianning, China.
Liu L; School of Pharmacy, Xianning Medical College, Hubei University of Science and Technology, Xianning, China.
Xie M; School of Pharmacy, Xianning Medical College, Hubei University of Science and Technology, Xianning, China.
Zhu HL; School of Pharmacy, Xianning Medical College, Hubei University of Science and Technology, Xianning, China.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2023 Apr 14; Vol. 18 (4), pp. e0284332. Date of Electronic Publication: 2023 Apr 14 (Print Publication: 2023).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Disabled Persons*
Motor Disorders*
Arthritis*
Mice ; Animals ; Humans ; Glycogen Synthase Kinase 3 beta ; Reactive Oxygen Species ; Neuroinflammatory Diseases ; Quality of Life ; Inflammation/drug therapy ; Pain/drug therapy ; Mitochondria ; Proto-Oncogene Proteins c-bcl-2

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Skocz do pozycji: 12.

Tytuł:: IL-1β knockdown inhibits cigarette smoke extract-induced inflammation and apoptosis in vascular smooth muscle cells.
Autorzy:: Jiang H; Department of Geriatrics, Wuhan Fourth Hospital, Affiliated Puai Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China.
Guo Z; Department of Emergency Medicine, Wuhan Fourth Hospital, Affiliated Puai Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China.
Zeng K; Department of Geriatrics, Wuhan Fourth Hospital, Affiliated Puai Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China.
Tang H; Department of Geriatrics, Wuhan Fourth Hospital, Affiliated Puai Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China.
Tan H; Department of Geriatrics, Wuhan Fourth Hospital, Affiliated Puai Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China.
Min R; Department of Geriatrics, Wuhan Fourth Hospital, Affiliated Puai Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China.
Huang C; Department of Geriatrics, Wuhan Fourth Hospital, Affiliated Puai Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2023 Feb 15; Vol. 18 (2), pp. e0277719. Date of Electronic Publication: 2023 Feb 15 (Print Publication: 2023).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cigarette Smoking*
Muscle, Smooth, Vascular*/metabolism
Animals ; Rats ; Apoptosis ; bcl-2-Associated X Protein/metabolism ; Inflammation/metabolism ; Interleukin-1beta/genetics ; Interleukin-1beta/metabolism ; Interleukin-6/metabolism ; Interleukin-8/metabolism ; Myocytes, Smooth Muscle/metabolism ; Pregnancy-Associated Plasma Protein-A/metabolism ; Proto-Oncogene Proteins c-bcl-2/metabolism ; RNA, Messenger/metabolism ; Nicotiana/genetics

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Skocz do pozycji: 13.

Tytuł:: Relative quantification of BCL2 mRNA for diagnostic usage needs stable uncontrolled genes as reference.
Autorzy:: Dwivedi N; Tumor Immunology Program, MSMF, MSMC, Narayana Health City, Bangalore, India.; MAHE, Manipal, India.
Mondal S; Tumor Immunology Program, MSMF, MSMC, Narayana Health City, Bangalore, India.
P K S; Tumor Immunology Program, MSMF, MSMC, Narayana Health City, Bangalore, India.
T S; Tumor Immunology Program, MSMF, MSMC, Narayana Health City, Bangalore, India.
Sachdeva K; Tumor Immunology Program, MSMF, MSMC, Narayana Health City, Bangalore, India.
Bathula C; Tumor Immunology Program, MSMF, MSMC, Narayana Health City, Bangalore, India.
K V; Tumor Immunology Program, MSMF, MSMC, Narayana Health City, Bangalore, India.
K S N; Department of Haematology, MSMF, MSMC, Narayana Health City, Bangalore, India.
Damodar S; Department of Haematology, MSMF, MSMC, Narayana Health City, Bangalore, India.
Dhar SK; Beyond Antibody, InCite Labs, MSMF, MSMC, Narayana Health City, Bangalore, India.
Das M; Tumor Immunology Program, MSMF, MSMC, Narayana Health City, Bangalore, India.; Beyond Antibody, InCite Labs, MSMF, MSMC, Narayana Health City, Bangalore, India.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2020 Aug 12; Vol. 15 (8), pp. e0236338. Date of Electronic Publication: 2020 Aug 12 (Print Publication: 2020).
Typ publikacji:: Journal Article; Observational Study; Research Support, Non-U.S. Gov't
MeSH Terms:: Biomarkers, Tumor/*isolation & purification
Hematologic Neoplasms/*diagnosis
Proto-Oncogene Proteins c-bcl-2/*isolation & purification
RNA, Messenger/*isolation & purification
RNA-Seq/*standards
Animals ; Biomarkers, Tumor/blood ; Biomarkers, Tumor/genetics ; Bone Marrow/pathology ; Cell Line, Tumor ; Datasets as Topic ; Disease Models, Animal ; Feasibility Studies ; Gene Expression Regulation, Neoplastic ; Genes, Essential ; Hematologic Neoplasms/blood ; Hematologic Neoplasms/genetics ; Hematologic Neoplasms/pathology ; Humans ; Leukocytes, Mononuclear ; Proto-Oncogene Proteins c-bcl-2/blood ; Proto-Oncogene Proteins c-bcl-2/genetics ; RNA, Messenger/blood ; RNA, Messenger/genetics ; Real-Time Polymerase Chain Reaction/standards ; Reference Standards

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Skocz do pozycji: 14.

Tytuł:: Phylogenetic analysis of the MCL1 BH3 binding groove and rBH3 sequence motifs in the p53 and INK4 protein families.
Autorzy:: McGriff A; Department of Biochemistry and Molecular Genetics, The University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
Placzek WJ; Department of Biochemistry and Molecular Genetics, The University of Alabama at Birmingham, Birmingham, Alabama, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2023 Jan 25; Vol. 18 (1), pp. e0277726. Date of Electronic Publication: 2023 Jan 25 (Print Publication: 2023).
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Apoptosis*
Tumor Suppressor Protein p53*/genetics
Tumor Suppressor Protein p53*/metabolism
Animals ; Cyclin-Dependent Kinase 4/metabolism ; Mammals/metabolism ; Myeloid Cell Leukemia Sequence 1 Protein/genetics ; Myeloid Cell Leukemia Sequence 1 Protein/metabolism ; Phylogeny ; Protein Binding ; Proto-Oncogene Proteins c-bcl-2/genetics ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Cyclin-Dependent Kinase Inhibitor Proteins/metabolism

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Skocz do pozycji: 15.

Tytuł:: B cell phenotypes and maturation states in cows naturally infected with Mycobacterium avium subsp. Paratuberculosis.
Autorzy:: Stabel JR; Infectious Bacterial Diseases of Livestock Research Unit, USDA-ARS, National Animal Disease Center, Ames, IA, United States of America.
Bannantine JP; Infectious Bacterial Diseases of Livestock Research Unit, USDA-ARS, National Animal Disease Center, Ames, IA, United States of America.
Humphrey S; Microscopy Services Department, USDA-ARS, National Animal Disease Center, Ames, IA, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2022 Dec 07; Vol. 17 (12), pp. e0278313. Date of Electronic Publication: 2022 Dec 07 (Print Publication: 2022).
Typ publikacji:: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Mycobacterium avium subsp. paratuberculosis*
Animals ; Cattle ; Female ; Leukocytes, Mononuclear ; Mycobacterium avium ; Proto-Oncogene Proteins c-bcl-2

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Skocz do pozycji: 16.

Tytuł:: EGFR mutations and AKT phosphorylation are markers for sensitivity to combined MCL-1 and BCL-2/xL inhibition in non-small cell lung cancer.
Autorzy:: Rice SJ; Penn State Hershey Cancer Institute, Hershey, Pennsylvania, United States of America.
Liu X; Penn State Hershey Cancer Institute, Hershey, Pennsylvania, United States of America.
Wang HG; Penn State Hershey Cancer Institute, Hershey, Pennsylvania, United States of America.; Department of Pediatrics, Penn State College of Medicine, Hershey, Pennsylvania, United States of America.
Belani CP; Penn State Hershey Cancer Institute, Hershey, Pennsylvania, United States of America.; Department of Medicine, Penn State College of Medicine, Hershey, Pennsylvania, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2019 May 31; Vol. 14 (5), pp. e0217657. Date of Electronic Publication: 2019 May 31 (Print Publication: 2019).
Typ publikacji:: Journal Article
MeSH Terms:: Carcinoma, Non-Small-Cell Lung/*drug therapy
Myeloid Cell Leukemia Sequence 1 Protein/*genetics
Proto-Oncogene Proteins c-bcl-2/*genetics
Antineoplastic Agents/pharmacology ; Apoptosis/drug effects ; Carcinoma, Non-Small-Cell Lung/genetics ; Carcinoma, Non-Small-Cell Lung/pathology ; Cell Line, Tumor ; Cell Survival/drug effects ; Drug Resistance, Neoplasm/genetics ; ErbB Receptors/antagonists & inhibitors ; ErbB Receptors/genetics ; Flow Cytometry ; Humans ; Mutation/genetics ; Myeloid Cell Leukemia Sequence 1 Protein/antagonists & inhibitors ; Oncogene Protein v-akt/genetics ; Phosphorylation/drug effects ; Proto-Oncogene Proteins c-bcl-2/antagonists & inhibitors ; Pyrroles/pharmacology ; bcl-X Protein/antagonists & inhibitors ; bcl-X Protein/genetics

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Skocz do pozycji: 17.

Tytuł:: Annona muricata L. peel extract inhibits carbohydrate metabolizing enzymes and reduces pancreatic β-cells, inflammation, and apoptosis via upregulation of PI3K/AKT genes.
Autorzy:: Ojo OA; Department of Biochemistry, Landmark University, Omu-Aran, Nigeria.
Grant S; Department of Biochemistry, Landmark University, Omu-Aran, Nigeria.
Amanze JC; Department of Biochemistry, Landmark University, Omu-Aran, Nigeria.
Oni AI; Department of Biochemistry, Landmark University, Omu-Aran, Nigeria.
Ojo AB; Department of Biochemistry, Ekiti State University, Ado-Ekiti, Nigeria.
Elebiyo TC; Department of Biochemistry, Landmark University, Omu-Aran, Nigeria.
Obafemi TO; Department of Biochemistry, Afe Babalola University, Ado-Ekiti, Nigeria.
Ayokunle DI; Department of Pure and Applied Biology, Bowen University, Iwo, Nigeria.
Ogunlakin AD; Department of Biochemistry, Bowen University, Iwo, Nigeria.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2022 Oct 27; Vol. 17 (10), pp. e0276984. Date of Electronic Publication: 2022 Oct 27 (Print Publication: 2022).
Typ publikacji:: Journal Article
MeSH Terms:: Annona*/chemistry
Diabetes Mellitus, Experimental*/drug therapy
Diabetes Mellitus, Experimental*/metabolism
Hypoglycemic Agents*/therapeutic use
Plant Extracts*/therapeutic use
Animals ; Rats ; Alloxan/pharmacology ; alpha-Amylases/metabolism ; alpha-Glucosidases/metabolism ; Apoptosis ; Blood Glucose/metabolism ; Inflammation/drug therapy ; Insulins/blood ; Phosphatidylinositol 3-Kinases/metabolism ; Proliferating Cell Nuclear Antigen/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Up-Regulation

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Skocz do pozycji: 18.

Tytuł:: Design, synthesis, anti-proliferative evaluation, docking, and MD simulations studies of new thiazolidine-2,4-diones targeting VEGFR-2 and apoptosis pathway.
Autorzy:: Taghour MS; Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.
Elkady H; Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.
Eldehna WM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.
El-Deeb N; Biopharmaceutical Products Research Department, Genetic Engineering and Biotechnology Research Institute, City of Scientific Research and Technological Applications (SRTA-City), Alexandria, Egypt.; Pharmaceutical and Fermentation Industries Development Center, City of Scientific Research and Technological Applications (SRTA City), Alexandria, Egypt.
Kenawy AM; Nucleic Acids Research Department, Genetic Engineering and Biotechnology Research Institute, City of Scientific Research and Technological Applications (SRTA-City), Alexandria, Egypt.
Elkaeed EB; Department of Pharmaceutical Sciences, College of Pharmacy, AlMaarefa University, Riyadh, Saudi Arabia.
Alsfouk BA; Department of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia.
Alesawy MS; Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.
Husein DZ; Chemistry Department, Faculty of Science, New Valley University, El-Kharja, Egypt.
Metwaly AM; Pharmaceutical and Fermentation Industries Development Center, City of Scientific Research and Technological Applications (SRTA City), Alexandria, Egypt.; Pharmacognosy and Medicinal Plants Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.
Eissa IH; Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2022 Sep 23; Vol. 17 (9), pp. e0272362. Date of Electronic Publication: 2022 Sep 23 (Print Publication: 2022).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Antineoplastic Agents*/pharmacology
Vascular Endothelial Growth Factor Receptor-2*/metabolism
Apoptosis ; Caco-2 Cells ; Cell Proliferation ; Drug Screening Assays, Antitumor ; Humans ; Molecular Docking Simulation ; Molecular Structure ; Protein Kinase Inhibitors/pharmacology ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Structure-Activity Relationship ; Survivin/metabolism ; Thiazolidines/pharmacology

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Tytuł:: NADPH-oxidase 4 gene over-expression in peripheral blood lymphocytes of the schizophrenia patients.
Autorzy:: Ershova ES; Research Centre for Medical Genetics, Moscow, Russia.
Shmarina GV; Research Centre for Medical Genetics, Moscow, Russia.
Martynov AV; Research Centre for Medical Genetics, Moscow, Russia.
Zakharova NV; N. A. Alexeev Clinical Psychiatric Hospital №1, Moscow Healthcare Department, Moscow, Russia.
Veiko RV; Research Centre for Medical Genetics, Moscow, Russia.
Umriukhin PE; Research Centre for Medical Genetics, Moscow, Russia.; Normal Physiology Departement, I.M. Sechenov First Moscow State Medical University, Moscow, Russia.
Kostyuk GP; N. A. Alexeev Clinical Psychiatric Hospital №1, Moscow Healthcare Department, Moscow, Russia.
Kutsev SI; Research Centre for Medical Genetics, Moscow, Russia.
Veiko NN; Research Centre for Medical Genetics, Moscow, Russia.
Kostyuk SV; Research Centre for Medical Genetics, Moscow, Russia.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2022 Jun 13; Vol. 17 (6), pp. e0269130. Date of Electronic Publication: 2022 Jun 13 (Print Publication: 2022).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Schizophrenia*/genetics
Schizophrenia*/metabolism
NADPH Oxidase 4/*metabolism
8-Hydroxy-2'-Deoxyguanosine ; Female ; Humans ; Leukocytes, Mononuclear/metabolism ; Lymphocytes/metabolism ; Male ; NADP/metabolism ; NADPH Oxidase 4/genetics ; Oxidative Stress ; Proto-Oncogene Proteins c-bcl-2/metabolism

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Tytuł:: Bcl-2-mediated control of TRAIL-induced apoptotic response in the non-small lung cancer cell line NCI-H460 is effective at late caspase processing steps.
Autorzy:: Danish L; Institute of Cell Biology and Immunology, University of Stuttgart, Stuttgart, Germany.
Imig D; Institute of Systems Theory and Automatic Control, University of Stuttgart, Stuttgart, Germany.
Allgöwer F; Institute of Systems Theory and Automatic Control, University of Stuttgart, Stuttgart, Germany.
Scheurich P; Institute of Cell Biology and Immunology, University of Stuttgart, Stuttgart, Germany.
Pollak N; Institute of Cell Biology and Immunology, University of Stuttgart, Stuttgart, Germany.; Institute of Systems Theory and Automatic Control, University of Stuttgart, Stuttgart, Germany.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2018 Jun 21; Vol. 13 (6), pp. e0198203. Date of Electronic Publication: 2018 Jun 21 (Print Publication: 2018).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Apoptosis*
Models, Biological*
Signal Transduction*
Carcinoma, Non-Small-Cell Lung/*metabolism
Caspases/*metabolism
Lung Neoplasms/*metabolism
Proto-Oncogene Proteins c-bcl-2/*metabolism
TNF-Related Apoptosis-Inducing Ligand/*metabolism
Carcinoma, Non-Small-Cell Lung/genetics ; Carcinoma, Non-Small-Cell Lung/pathology ; Caspases/genetics ; HCT116 Cells ; HeLa Cells ; Humans ; Lung Neoplasms/genetics ; Lung Neoplasms/pathology ; Proto-Oncogene Proteins c-bcl-2/genetics ; TNF-Related Apoptosis-Inducing Ligand/genetics ; X-Linked Inhibitor of Apoptosis Protein/genetics ; X-Linked Inhibitor of Apoptosis Protein/metabolism

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