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Tytuł:
Ceragenin-mediated disruption of Pseudomonas aeruginosa biofilms.
Autorzy:
Wnorowska U; Department of Medical Microbiology and Nanobiomedical Engineering, Medical University of Białystok, Białystok, Poland.
Łysik D; Institute of Biomedical Engineering, Bialystok University of Technology, Bialystok, Poland.
Piktel E; Independent Laboratory of Nanomedicine, Medical University of Białystok, Białystok, Poland.
Zakrzewska M; Department of Medical Microbiology and Nanobiomedical Engineering, Medical University of Białystok, Białystok, Poland.
Okła S; Institute of Medical Sciences, Collegium Medicum, Jan Kochanowski University of Kielce, Kielce, Poland.
Lesiak A; Institute of Medical Sciences, Collegium Medicum, Jan Kochanowski University of Kielce, Kielce, Poland.
Spałek J; Institute of Medical Sciences, Collegium Medicum, Jan Kochanowski University of Kielce, Kielce, Poland.
Mystkowska J; Institute of Biomedical Engineering, Bialystok University of Technology, Bialystok, Poland.
Savage PB; Department of Chemistry and Biochemistry, Brigham Young University, Provo, Utah, United States of America.
Janmey P; Department of Physiology and Institute for Medicine and Engineering, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
Fiedoruk K; Department of Medical Microbiology and Nanobiomedical Engineering, Medical University of Białystok, Białystok, Poland.
Bucki R; Department of Medical Microbiology and Nanobiomedical Engineering, Medical University of Białystok, Białystok, Poland.
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Źródło:
PloS one [PLoS One] 2024 Feb 12; Vol. 19 (2), pp. e0298112. Date of Electronic Publication: 2024 Feb 12 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Anti-Infective Agents*/pharmacology
Cystic Fibrosis*
Pseudomonas Infections*
Steroids*
Humans ; Pseudomonas aeruginosa ; Aspartic Acid ; Expectorants ; Anti-Bacterial Agents/pharmacology ; Biofilms ; Deoxyribonuclease I ; Microbial Sensitivity Tests
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cystic Fibrosis Mice Are Highly Susceptible to Repeated Acute Pseudomonas aeruginosa Pneumonia after Intranasal Inoculation.
Autorzy:
Manzor M; Department of Anesthesiology, Critical Care and Pain Medicine, Cardiac Anesthesia Division, Boston Children's Hospital, Boston, USA.
Koutsogiannaki S; Department of Anesthesiology, Critical Care and Pain Medicine, Cardiac Anesthesia Division, Boston Children's Hospital, Boston, USA.; Department of Anaesthesia, Harvard Medical School, Boston, USA.; Department of Immunology, Harvard Medical School, Boston, USA.; Broad Institute of MIT and Harvard, Cambridge, USA.
DiBlasi M; Department of Anesthesiology, Critical Care and Pain Medicine, Critical Care Division, Boston Children's Hospital, Boston, USA.
Schaefers M; Department of Anaesthesia, Harvard Medical School, Boston, USA.; Department of Anesthesiology, Critical Care and Pain Medicine, Critical Care Division, Boston Children's Hospital, Boston, USA.
Priebe G; Department of Anaesthesia, Harvard Medical School, Boston, USA.; Broad Institute of MIT and Harvard, Cambridge, USA.; Department of Anesthesiology, Critical Care and Pain Medicine, Critical Care Division, Boston Children's Hospital, Boston, USA.; Department of Pediatrics, Division of Infectious Diseases, Boston Children's Hospital, Boston, USA.
Yuki K; Department of Anesthesiology, Critical Care and Pain Medicine, Cardiac Anesthesia Division, Boston Children's Hospital, Boston, USA.; Department of Anaesthesia, Harvard Medical School, Boston, USA.; Department of Immunology, Harvard Medical School, Boston, USA.; Broad Institute of MIT and Harvard, Cambridge, USA.
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Źródło:
BioMed research international [Biomed Res Int] 2024 Feb 05; Vol. 2024, pp. 4769779. Date of Electronic Publication: 2024 Feb 05 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Cystic Fibrosis*/genetics
Cystic Fibrosis*/microbiology
Pneumonia*/complications
Pseudomonas Infections*/microbiology
Humans ; Mice ; Animals ; Cystic Fibrosis Transmembrane Conductance Regulator/genetics ; Pseudomonas aeruginosa ; Persistent Infection ; Mice, Transgenic
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Analysis of Pseudomonas aeruginosa Isolates from Patients with Cystic Fibrosis Revealed Novel Groups of Filamentous Bacteriophages.
Autorzy:
Evseev P; Laboratory of Molecular Microbiology, Pirogov Russian National Research Medical University, Ostrovityanova 1, 117997 Moscow, Russia.; Laboratory of Molecular Bioengineering, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya 16/10, 117997 Moscow, Russia.
Bocharova J; Laboratory of Molecular Microbiology, Pirogov Russian National Research Medical University, Ostrovityanova 1, 117997 Moscow, Russia.
Shagin D; Laboratory of Molecular Microbiology, Pirogov Russian National Research Medical University, Ostrovityanova 1, 117997 Moscow, Russia.
Chebotar I; Laboratory of Molecular Microbiology, Pirogov Russian National Research Medical University, Ostrovityanova 1, 117997 Moscow, Russia.
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Źródło:
Viruses [Viruses] 2023 Nov 05; Vol. 15 (11). Date of Electronic Publication: 2023 Nov 05.
Typ publikacji:
Journal Article
MeSH Terms:
Pseudomonas Phages*/genetics
Cystic Fibrosis*/microbiology
Inovirus*/genetics
Bacteriophages*
Pseudomonas Infections*/microbiology
Animals ; Humans ; Pseudomonas aeruginosa/genetics ; Phylogeny ; Prophages/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Inovirus Pf4 Triggers Antiviral Responses and Disrupts the Proliferation of Airway Basal Epithelial Cells.
Autorzy:
Popescu MC; Department of Infectious Diseases, Stanford University, Stanford, CA 94305, USA.; Immunology Program, Stanford University, Stanford, CA 94305, USA.
Haddock NL; Department of Infectious Diseases, Stanford University, Stanford, CA 94305, USA.; Immunology Program, Stanford University, Stanford, CA 94305, USA.
Burgener EB; Center for Excellence in Pulmonary Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Rojas-Hernandez LS; Center for Excellence in Pulmonary Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Kaber G; Department of Infectious Diseases, Stanford University, Stanford, CA 94305, USA.
Hargil A; Department of Infectious Diseases, Stanford University, Stanford, CA 94305, USA.
Bollyky PL; Department of Infectious Diseases, Stanford University, Stanford, CA 94305, USA.
Milla CE; Center for Excellence in Pulmonary Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.
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Źródło:
Viruses [Viruses] 2024 Jan 22; Vol. 16 (1). Date of Electronic Publication: 2024 Jan 22.
Typ publikacji:
Journal Article
MeSH Terms:
Cystic Fibrosis*
Pseudomonas Infections*/microbiology
Animals ; Humans ; Respiratory System ; Epithelial Cells ; Epithelium ; Cell Proliferation ; Antiviral Agents ; Pseudomonas aeruginosa/physiology ; Mammals
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Binding of Pseudomonas aeruginosa to Cystic Fibrosis Bronchial Epithelial Model Cells Alters the Composition of the Exosomes They Produce Compared to Healthy Control Cells.
Autorzy:
Lozano-Iturbe V; Department of Functional Biology, University of Oviedo, 33006 Oviedo, Spain.; Instituto Universitario Fernández-Vega, Fundación de Investigación Oftalmológica, University of Oviedo, 33012 Oviedo, Spain.; Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), 33011 Oviedo, Spain.
Blanco-Agudín N; Department of Functional Biology, University of Oviedo, 33006 Oviedo, Spain.; Instituto Universitario Fernández-Vega, Fundación de Investigación Oftalmológica, University of Oviedo, 33012 Oviedo, Spain.; Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), 33011 Oviedo, Spain.
Vázquez-Espinosa E; Pneumology Service, Institute for Health Research (IP), Hospital Universitario de La Princesa, 28006 Madrid, Spain.
Fernández-Vega I; Instituto Universitario Fernández-Vega, Fundación de Investigación Oftalmológica, University of Oviedo, 33012 Oviedo, Spain.; Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), 33011 Oviedo, Spain.; Department of Pathology, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.
Merayo-Lloves J; Instituto Universitario Fernández-Vega, Fundación de Investigación Oftalmológica, University of Oviedo, 33012 Oviedo, Spain.; Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), 33011 Oviedo, Spain.
Vazquez F; Department of Functional Biology, University of Oviedo, 33006 Oviedo, Spain.; Instituto Universitario Fernández-Vega, Fundación de Investigación Oftalmológica, University of Oviedo, 33012 Oviedo, Spain.; Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), 33011 Oviedo, Spain.; Department of Microbiology, Hospital Universitario Central de Asturias, 33011 Oviedo, Spain.
Girón RM; Pneumology Service, Institute for Health Research (IP), Hospital Universitario de La Princesa, 28006 Madrid, Spain.
Quirós LM; Department of Functional Biology, University of Oviedo, 33006 Oviedo, Spain.; Instituto Universitario Fernández-Vega, Fundación de Investigación Oftalmológica, University of Oviedo, 33012 Oviedo, Spain.; Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), 33011 Oviedo, Spain.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 11; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 11.
Typ publikacji:
Journal Article
MeSH Terms:
Exosomes*
Cystic Fibrosis*/genetics
Pseudomonas Infections*
MicroRNAs*/genetics
Humans ; Pseudomonas aeruginosa ; Proteomics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Predictive modeling of antibiotic eradication therapy success for new-onset Pseudomonas aeruginosa pulmonary infections in children with cystic fibrosis.
Autorzy:
Graña-Miraglia L; Department of Cell and Systems Biology, University of Toronto, Toronto, Ontario, Canada.
Morales-Lizcano N; Department of Cell and Systems Biology, University of Toronto, Toronto, Ontario, Canada.
Wang PW; Department of Cell and Systems Biology, University of Toronto, Toronto, Ontario, Canada.; Centre for the Analysis of Genome Evolution and Function, University of Toronto, Toronto, Ontario, Canada.
Hwang DM; Department of Laboratory Medicine and Pathobiology, Toronto, Ontario, Canada.; Laboratory Medicine and Molecular Diagnostics, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
Yau YCW; Department of Laboratory Medicine and Pathobiology, Toronto, Ontario, Canada.; Department of Paediatric Laboratory Medicine, Division of Microbiology, The Hospital for Sick Children, Toronto, Ontario, Canada.
Waters VJ; Department of Pediatrics, Division of Infectious Diseases, The Hospital for Sick Children, Toronto, Ontario, Canada.; Translational Medicine, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada.
Guttman DS; Department of Cell and Systems Biology, University of Toronto, Toronto, Ontario, Canada.; Centre for the Analysis of Genome Evolution and Function, University of Toronto, Toronto, Ontario, Canada.
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Źródło:
PLoS computational biology [PLoS Comput Biol] 2023 Sep 06; Vol. 19 (9), pp. e1011424. Date of Electronic Publication: 2023 Sep 06 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cystic Fibrosis*/complications
Cystic Fibrosis*/drug therapy
Pseudomonas Infections*/complications
Pseudomonas Infections*/drug therapy
Humans ; Child ; Pseudomonas aeruginosa ; Cell Aggregation ; Lung ; Anti-Bacterial Agents/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Limited effects of azithromycin on the oropharyngeal microbiome in children with CF and early pseudomonas infection.
Autorzy:
Wagner BD; Department of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado, Aurora, CO, USA. .; Children's Hospital Colorado, Aurora, CO, USA. .
Zemanick ET; Children's Hospital Colorado, Aurora, CO, USA.; Department of Pediatrics, University of Colorado, Aurora, CO, USA.
Sagel SD; Children's Hospital Colorado, Aurora, CO, USA.; Department of Pediatrics, University of Colorado, Aurora, CO, USA.
Robertson CE; Department of Infectious Diseases, University of Colorado, Aurora, CO, USA.
Stevens MJ; Children's Hospital Colorado, Aurora, CO, USA.; Department of Pediatrics, University of Colorado, Aurora, CO, USA.
Mayer-Hamblett N; Department of Pediatrics, University of Washington, Seattle, WA, USA.; Department of Biostatistics, University of Washington, Seattle, WA, USA.; Seattle Children's Hospital, Seattle, WA, USA.
Retsch-Bogart G; Department of Pediatrics, University of North Carolina, Chapel Hill, NC, USA.
Ramsey BW; Department of Pediatrics, University of Washington, Seattle, WA, USA.; Seattle Children's Hospital, Seattle, WA, USA.
Harris JK; Children's Hospital Colorado, Aurora, CO, USA.; Department of Pediatrics, University of Colorado, Aurora, CO, USA.
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Źródło:
BMC microbiology [BMC Microbiol] 2023 Oct 27; Vol. 23 (1), pp. 312. Date of Electronic Publication: 2023 Oct 27.
Typ publikacji:
Multicenter Study; Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Pseudomonas Infections*/drug therapy
Cystic Fibrosis*/complications
Cystic Fibrosis*/drug therapy
Cystic Fibrosis*/microbiology
Microbiota*/genetics
Humans ; Child ; Azithromycin/pharmacology ; Azithromycin/therapeutic use ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Administration, Inhalation ; Pseudomonas aeruginosa/genetics ; Tobramycin/pharmacology ; Bacteria/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Involvement of Acquired Tobramycin Resistance in the Shift to the Viable but Non-Culturable State in Pseudomonas aeruginosa .
Autorzy:
Mangiaterra G; Department of Biomolecular Sciences, University of Urbino Carlo Bo, Via S. Chiara 27, 61029 Urbino, Italy.; Department of Life and Environmental Sciences, Polytechnic University of Marche, Via Brecce Bianche, 60131 Ancona, Italy.
Cedraro N; Department of Life and Environmental Sciences, Polytechnic University of Marche, Via Brecce Bianche, 60131 Ancona, Italy.
Vaiasicca S; Department of Molecular and Clinical Sciences, Polytechnic University of Marche, Via Tronto 10/a, 60020 Ancona, Italy.
Citterio B; Department of Biomolecular Sciences, University of Urbino Carlo Bo, Via S. Chiara 27, 61029 Urbino, Italy.
Frangipani E; Department of Biomolecular Sciences, University of Urbino Carlo Bo, Via S. Chiara 27, 61029 Urbino, Italy.
Biavasco F; Department of Life and Environmental Sciences, Polytechnic University of Marche, Via Brecce Bianche, 60131 Ancona, Italy.
Vignaroli C; Department of Life and Environmental Sciences, Polytechnic University of Marche, Via Brecce Bianche, 60131 Ancona, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jul 18; Vol. 24 (14). Date of Electronic Publication: 2023 Jul 18.
Typ publikacji:
Journal Article
MeSH Terms:
Pseudomonas Infections*/microbiology
Cystic Fibrosis*/drug therapy
Humans ; Tobramycin/pharmacology ; Pseudomonas aeruginosa ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Aminoglycosides/pharmacology ; Microbial Sensitivity Tests
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
How Three Self-Secreted Biofilm Exopolysaccharides of Pseudomonas aeruginosa , Psl, Pel, and Alginate, Can Each Be Exploited for Antibiotic Adjuvant Effects in Cystic Fibrosis Lung Infection.
Autorzy:
Chung J; Department of Translational Medicine, Research Institute, The Hospital for Sick Children, University of Toronto, 686 Bay Street, Toronto, ON M5G 0A4, Canada.
Eisha S; Department of Translational Medicine, Research Institute, The Hospital for Sick Children, University of Toronto, 686 Bay Street, Toronto, ON M5G 0A4, Canada.
Park S; Department of Translational Medicine, Research Institute, The Hospital for Sick Children, University of Toronto, 686 Bay Street, Toronto, ON M5G 0A4, Canada.
Morris AJ; Department of Translational Medicine, Research Institute, The Hospital for Sick Children, University of Toronto, 686 Bay Street, Toronto, ON M5G 0A4, Canada.
Martin I; Department of Translational Medicine, Research Institute, The Hospital for Sick Children, University of Toronto, 686 Bay Street, Toronto, ON M5G 0A4, Canada.; Division of Respiratory Medicine, Department of Paediatrics, The Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, ON M5G 1X8, Canada.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 May 13; Vol. 24 (10). Date of Electronic Publication: 2023 May 13.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Cystic Fibrosis*/drug therapy
Pseudomonas Infections*/drug therapy
Humans ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Anti-Bacterial Agents/metabolism ; Pseudomonas aeruginosa/metabolism ; Alginates/metabolism ; Biofilms ; Adjuvants, Immunologic/therapeutic use ; Adjuvants, Pharmaceutic/therapeutic use ; Lung
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Phenotypic and genotypic characteristics of Pseudomonas aeruginosa isolated from cystic fibrosis patients with chronic infections.
Autorzy:
Iwańska A; Department of Microbiology, National Tuberculosis and Lung Diseases Research Institute, Warsaw, Poland. .
Trafny EA; Biomedical Engineering Centre, Institute of Optoelectronics, Military University of Technology, Warsaw, Poland.
Czopowicz M; Division of Veterinary Epidemiology and Economics, Institute of Veterinary Medicine, Warsaw University of Life Sciences-SGGW, Warsaw, Poland.
Augustynowicz-Kopeć E; Department of Microbiology, National Tuberculosis and Lung Diseases Research Institute, Warsaw, Poland.
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Źródło:
Scientific reports [Sci Rep] 2023 Jul 20; Vol. 13 (1), pp. 11741. Date of Electronic Publication: 2023 Jul 20.
Typ publikacji:
Journal Article
MeSH Terms:
Cystic Fibrosis*/drug therapy
Pseudomonas Infections*/drug therapy
Adult ; Humans ; Pseudomonas aeruginosa ; Persistent Infection ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Genotype
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Microbiology sampling in non-cystic fibrosis bronchiectasis cases from northern Alberta.
Autorzy:
Wagner MJ; Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Dimitrov M; Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Lam GY; Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.; Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Leung W; Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.; Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Tyrrell GJ; Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.; Provincial Laboratory for Public Health, Alberta Health Services, Edmonton, Alberta, Canada.
Vethanayagam D; Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.; Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
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Źródło:
PloS one [PLoS One] 2023 Jul 14; Vol. 18 (7), pp. e0288704. Date of Electronic Publication: 2023 Jul 14 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Bronchiectasis*/complications
Cystic Fibrosis*/complications
Cystic Fibrosis*/drug therapy
Pseudomonas Infections*/drug therapy
Humans ; Retrospective Studies ; Alberta/epidemiology ; Sputum/microbiology ; Fibrosis ; Pseudomonas aeruginosa ; Anti-Bacterial Agents/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Novel Co-Culture Model Reveals Enhanced CFTR Rescue in Primary Cystic Fibrosis Airway Epithelial Cultures with Persistent Pseudomonas aeruginosa Infection.
Autorzy:
Cholon DM; Marsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.
Greenwald MA; Marsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.; Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, NC 27599, USA.
Higgs MG; Marsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.; Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, NC 27599, USA.
Quinney NL; Marsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.
Boyles SE; Marsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.
Meinig SL; Marsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.; Pharmaceutical Product Development (PPD), Thermo Fisher Scientific, Morrisville, NC 27560, USA.
Minges JT; Marsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.
Chaubal A; Marsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.
Tarran R; Marsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.; Division of Genetic, Department of Internal Medicine, Environmental and Inhalational Disease, University of Kansas Medical Center, Kansas City, KS 66160, USA.
Ribeiro CMP; Marsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.; Division of Pulmonary Diseases, Department of Medicine, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.; Department of Cell Biology and Physiology, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.
Wolfgang MC; Marsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.; Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, NC 27599, USA.
Gentzsch M; Marsico Lung Institute and Cystic Fibrosis Research Center, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.; Department of Cell Biology and Physiology, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.; Division of Pediatric Pulmonology, Department of Pediatrics, School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.
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Źródło:
Cells [Cells] 2023 Nov 13; Vol. 12 (22). Date of Electronic Publication: 2023 Nov 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cystic Fibrosis*/metabolism
Pseudomonas Infections*/drug therapy
Pseudomonas Infections*/microbiology
Humans ; Cystic Fibrosis Transmembrane Conductance Regulator/genetics ; Cystic Fibrosis Transmembrane Conductance Regulator/metabolism ; Coculture Techniques ; Lung/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
How Staphylococcus aureus and Pseudomonas aeruginosa Hijack the Host Immune Response in the Context of Cystic Fibrosis.
Autorzy:
Souche A; Centre International de Recherche en Infectiologie, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, 69007 Lyon, France.; Institut des Agents Infectieux, Hospices Civils de Lyon, 69002 Lyon, France.
Vandenesch F; Centre International de Recherche en Infectiologie, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, 69007 Lyon, France.; Institut des Agents Infectieux, Hospices Civils de Lyon, 69002 Lyon, France.
Doléans-Jordheim A; Centre International de Recherche en Infectiologie, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, 69007 Lyon, France.; Institut des Agents Infectieux, Hospices Civils de Lyon, 69002 Lyon, France.
Moreau K; Centre International de Recherche en Infectiologie, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, 69007 Lyon, France.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Apr 01; Vol. 24 (7). Date of Electronic Publication: 2023 Apr 01.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Cystic Fibrosis*/microbiology
Staphylococcal Infections*/microbiology
Pseudomonas Infections*/microbiology
Humans ; Staphylococcus aureus/physiology ; Pseudomonas aeruginosa/physiology ; Lung/microbiology ; Immunity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Anti-Virulence Potential of a Chionodracine-Derived Peptide against Multidrug-Resistant Pseudomonas aeruginosa Clinical Isolates from Cystic Fibrosis Patients.
Autorzy:
Artini M; Department of Public Health and Infectious Diseases, Sapienza University, p.le Aldo Moro 5, 00185 Rome, Italy.
Imperlini E; Department for Innovation in Biological, Agro-Food and Forest Systems, University of Tuscia, 01100 Viterbo, Italy.
Buonocore F; Department for Innovation in Biological, Agro-Food and Forest Systems, University of Tuscia, 01100 Viterbo, Italy.
Relucenti M; Department of Anatomy, Histology, Forensic Medicine and Orthopedics, Sapienza University of Rome, Via Alfonso Borelli 50, 00161 Rome, Italy.
Porcelli F; Department for Innovation in Biological, Agro-Food and Forest Systems, University of Tuscia, 01100 Viterbo, Italy.
Donfrancesco O; Department of Anatomy, Histology, Forensic Medicine and Orthopedics, Sapienza University of Rome, Via Alfonso Borelli 50, 00161 Rome, Italy.
Tuccio Guarna Assanti V; Research Unit of Diagnostical and Management Innovations, Children's Hospital and Institute Research Bambino Gesù, 00165 Rome, Italy.
Fiscarelli EV; Research Unit of Diagnostical and Management Innovations, Children's Hospital and Institute Research Bambino Gesù, 00165 Rome, Italy.
Papa R; Department of Public Health and Infectious Diseases, Sapienza University, p.le Aldo Moro 5, 00185 Rome, Italy.
Selan L; Department of Public Health and Infectious Diseases, Sapienza University, p.le Aldo Moro 5, 00185 Rome, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Nov 04; Vol. 23 (21). Date of Electronic Publication: 2022 Nov 04.
Typ publikacji:
Journal Article
MeSH Terms:
Cystic Fibrosis*/drug therapy
Cystic Fibrosis*/microbiology
Pseudomonas Infections*/drug therapy
Pseudomonas Infections*/microbiology
Humans ; Pseudomonas aeruginosa ; Virulence ; Biofilms ; Virulence Factors/metabolism ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/metabolism ; Peptides/pharmacology ; Peptides/metabolism ; Microbial Sensitivity Tests
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Pseudomonas aeruginosa : Infections, Animal Modeling, and Therapeutics.
Autorzy:
Wood SJ; Department of Medicine, Division of Hematology, Oncology, & Cell Therapy, Rush University Medical Center, Chicago, IL 60612, USA.; Department of Microbial Pathogens and Immunity, Rush University Medical Center, Chicago, IL 60612, USA.
Kuzel TM; Department of Medicine, Division of Hematology, Oncology, & Cell Therapy, Rush University Medical Center, Chicago, IL 60612, USA.; Cancer Center, Rush University Medical Center, Chicago, IL 60612, USA.
Shafikhani SH; Department of Medicine, Division of Hematology, Oncology, & Cell Therapy, Rush University Medical Center, Chicago, IL 60612, USA.; Department of Microbial Pathogens and Immunity, Rush University Medical Center, Chicago, IL 60612, USA.; Cancer Center, Rush University Medical Center, Chicago, IL 60612, USA.
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Źródło:
Cells [Cells] 2023 Jan 03; Vol. 12 (1). Date of Electronic Publication: 2023 Jan 03.
Typ publikacji:
Journal Article; Review; Research Support, N.I.H., Extramural
MeSH Terms:
Pseudomonas Infections*/drug therapy
Cystic Fibrosis*/drug therapy
Animals ; Pseudomonas aeruginosa ; Persistent Infection ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Models, Animal
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Pseudomonas aeruginosa aggregation and Psl expression in sputum is associated with antibiotic eradication failure in children with cystic fibrosis.
Autorzy:
Morris AJ; Translational Medicine, Research Institute, Hospital for Sick Children, Toronto, ON, Canada.
Yau YCW; Division of Microbiology, Department of Pediatric Laboratory Medicine, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.
Park S; Translational Medicine, Research Institute, Hospital for Sick Children, Toronto, ON, Canada.
Eisha S; Translational Medicine, Research Institute, Hospital for Sick Children, Toronto, ON, Canada.
McDonald N; Division of Respiratory Medicine, Hospital for Sick Children, Toronto, ON, Canada.
Parsek MR; Department of Microbiology, University of Washington, Seattle, WA, USA.
Howell PL; Program in Molecular Medicine, Research Institute, Hospital for Sick Children, Toronto, ON, Canada.; Department of Biochemistry, University of Toronto, Toronto, ON, Canada.
Hoffman LR; Departments of Pediatrics and Microbiology, University of Washington, Seattle, WA, USA.
Nguyen D; Meakins-Christie Laboratories, Research Institute of the McGill University Health Centre, Montreal, QC, Canada.; Department of Medicine, McGill University, Montreal, QC, Canada.
DiGiandomenico A; Vaccines and Immune Therapies, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA.
Rooney AM; Division of Infectious Diseases, Department of Medicine, University of Toronto, Toronto, ON, Canada.
Coburn B; Division of Infectious Diseases, Department of Medicine, University of Toronto, Toronto, ON, Canada.
Grana-Miraglia L; Department of Cell and Systems Biology, University of Toronto, Toronto, ON, Canada.
Wang P; Department of Cell and Systems Biology, University of Toronto, Toronto, ON, Canada.
Guttman DS; Department of Cell and Systems Biology, University of Toronto, Toronto, ON, Canada.
Wozniak DJ; Departments of Microbial Infection and Immunity, Microbiology, Ohio State University, Columbus, OH, USA.
Waters VJ; Translational Medicine, Research Institute, Hospital for Sick Children, Toronto, ON, Canada. .; Division of Infectious Diseases, Department of Pediatrics, Hospital for Sick Children, 555 University Avenue, Toronto, ON, M5G 1X8, Canada. .
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Źródło:
Scientific reports [Sci Rep] 2022 Dec 12; Vol. 12 (1), pp. 21444. Date of Electronic Publication: 2022 Dec 12.
Typ publikacji:
Observational Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cystic Fibrosis*/complications
Cystic Fibrosis*/drug therapy
Pseudomonas Infections*/drug therapy
Pseudomonas Infections*/complications
Child ; Humans ; Pseudomonas aeruginosa/metabolism ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Tobramycin/therapeutic use ; Tobramycin/metabolism ; Sputum
Czasopismo naukowe
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Tytuł:
Response to inhaled ceftazidime in patients with non-cystic fibrosis bronchiectasis and chronic bronchial infection unrelated to Pseudomonas aeruginosa.
Autorzy:
Riveiro V; Pulmonology Department, University Clinical Hospital of Santiago, Santiago de Compostela, Spain.
Casal A; Pulmonology Department, University Clinical Hospital of Santiago, Santiago de Compostela, Spain.
Álvarez-Dobaño JM; Pulmonology Department, University Clinical Hospital of Santiago, Santiago de Compostela, Spain.; Interdisciplinary Research Group in Pulmonology, Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, Spain.
Lourido T; Pulmonology Department, University Clinical Hospital of Santiago, Santiago de Compostela, Spain.
Suárez-Artime P; Pharmacy Department, University Clinical Hospital of Santiago, Santiago de Compostela, Spain.
Rodríguez-García C; Pulmonology Department, University Clinical Hospital of Santiago, Santiago de Compostela, Spain.
Ferreiro L; Pulmonology Department, University Clinical Hospital of Santiago, Santiago de Compostela, Spain.; Interdisciplinary Research Group in Pulmonology, Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, Spain.
Toubes ME; Pulmonology Department, University Clinical Hospital of Santiago, Santiago de Compostela, Spain.
Valdés L; Pulmonology Department, University Clinical Hospital of Santiago, Santiago de Compostela, Spain.; Interdisciplinary Research Group in Pulmonology, Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, Spain.; University of Santiago de Compostela, Santiago de Compostela, Spain.
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Źródło:
The clinical respiratory journal [Clin Respir J] 2022 Nov; Vol. 16 (11), pp. 768-773. Date of Electronic Publication: 2022 Aug 26.
Typ publikacji:
Journal Article
MeSH Terms:
Pseudomonas Infections*/complications
Pseudomonas Infections*/drug therapy
Bronchiectasis*/complications
Cystic Fibrosis*/complications
Cystic Fibrosis*/drug therapy
Bronchitis, Chronic*
Humans ; Pseudomonas aeruginosa ; Ceftazidime/therapeutic use ; Administration, Inhalation ; Anti-Bacterial Agents/therapeutic use ; Fibrosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Pseudomonas aeruginosa adaptation in cystic fibrosis patients increases C5a levels and promotes neutrophil recruitment.
Autorzy:
Mateu-Borrás M; Instituto Universitario de Investigación En Ciencias de La Salud, Universidad de Las Islas Baleares and Instituto de Investigación Sanitaria de Les Illes Balears, Palma de Mallorca, Spain.
González-Alsina A; Instituto Universitario de Investigación En Ciencias de La Salud, Universidad de Las Islas Baleares and Instituto de Investigación Sanitaria de Les Illes Balears, Palma de Mallorca, Spain.
Doménech-Sánchez A; Instituto Universitario de Investigación En Ciencias de La Salud, Universidad de Las Islas Baleares and Instituto de Investigación Sanitaria de Les Illes Balears, Palma de Mallorca, Spain.
Querol-García J; Centro de Investigaciones Biológicas Margarita Salas, Consejo Superior de Investigaciones Científicas, Madrid, Spain.
Fernández FJ; Centro de Investigaciones Biológicas Margarita Salas, Consejo Superior de Investigaciones Científicas, Madrid, Spain.
Vega MC; Centro de Investigaciones Biológicas Margarita Salas, Consejo Superior de Investigaciones Científicas, Madrid, Spain.
Albertí S; Instituto Universitario de Investigación En Ciencias de La Salud, Universidad de Las Islas Baleares and Instituto de Investigación Sanitaria de Les Illes Balears, Palma de Mallorca, Spain.
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Źródło:
Virulence [Virulence] 2022 Dec; Vol. 13 (1), pp. 215-224.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cystic Fibrosis*/complications
Cystic Fibrosis*/microbiology
Pseudomonas Infections*/microbiology
Complement C5a/*analysis
Humans ; Neutrophil Infiltration ; Peptide Hydrolases/metabolism ; Pseudomonas aeruginosa/metabolism ; Respiratory System
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Serratiopeptidase Affects the Physiology of Pseudomonas aeruginosa Isolates from Cystic Fibrosis Patients.
Autorzy:
Artini M; Department of Public Health and Infectious Diseases, Sapienza University, p.le Aldo Moro 5, 00185 Rome, Italy.
Vrenna G; Department of Public Health and Infectious Diseases, Sapienza University, p.le Aldo Moro 5, 00185 Rome, Italy.
Trecca M; Department of Public Health and Infectious Diseases, Sapienza University, p.le Aldo Moro 5, 00185 Rome, Italy.
Tuccio Guarna Assanti V; Research Unit of Diagnostical and Management Innovations, Children's Hospital and Institute Research Bambino Gesù, 00165 Rome, Italy.
Fiscarelli EV; Research Unit of Diagnostical and Management Innovations, Children's Hospital and Institute Research Bambino Gesù, 00165 Rome, Italy.
Papa R; Department of Public Health and Infectious Diseases, Sapienza University, p.le Aldo Moro 5, 00185 Rome, Italy.
Selan L; Department of Public Health and Infectious Diseases, Sapienza University, p.le Aldo Moro 5, 00185 Rome, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Oct 20; Vol. 23 (20). Date of Electronic Publication: 2022 Oct 20.
Typ publikacji:
Journal Article
MeSH Terms:
Cystic Fibrosis*/microbiology
Pseudomonas Infections*/microbiology
Humans ; Pseudomonas aeruginosa/physiology ; Pyocyanine ; Biofilms ; Metalloproteases
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Sense and Nonsense of Antimicrobial Susceptibility Testing in Cystic Fibrosis.
Autorzy:
LiPuma JJ; Division of Pediatric Infectious Diseases, Department of Pediatrics, University of Michigan Medical School, Ann Arbor, Michigan, USA.
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Źródło:
Journal of the Pediatric Infectious Diseases Society [J Pediatric Infect Dis Soc] 2022 Sep 07; Vol. 11 (Supplement_2), pp. S46-S52.
Typ publikacji:
Journal Article
MeSH Terms:
Cystic Fibrosis*/complications
Cystic Fibrosis*/drug therapy
Pseudomonas Infections*/drug therapy
Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Humans ; Microbial Sensitivity Tests ; Pseudomonas aeruginosa
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
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