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Tytuł :
Suppression of ventral hippocampal CA1 pyramidal neuronal activities enhances water intake.
Autorzy :
Han B; Neuroscience Research Institute and Department of Neurobiology, School of Basic Medical Sciences, Peking University, Beijing, People's Republic of China.
Cui S; Neuroscience Research Institute and Department of Neurobiology, School of Basic Medical Sciences, Peking University, Beijing, People's Republic of China.
Liu FY; Neuroscience Research Institute and Department of Neurobiology, School of Basic Medical Sciences, Peking University, Beijing, People's Republic of China.
Wan Y; Neuroscience Research Institute and Department of Neurobiology, School of Basic Medical Sciences, Peking University, Beijing, People's Republic of China.; Key Laboratory for Neuroscience, Ministry of Education/National Health Commission, Peking University, Beijing, People's Republic of China.
Shi Y; School of Automation Science and Electrical Engineering, Beihang University, Beijing, People's Republic of China.
Yi M; Neuroscience Research Institute and Department of Neurobiology, School of Basic Medical Sciences, Peking University, Beijing, People's Republic of China.; Key Laboratory for Neuroscience, Ministry of Education/National Health Commission, Peking University, Beijing, People's Republic of China.
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Źródło :
American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2021 Dec 01; Vol. 321 (6), pp. C992-C999. Date of Electronic Publication: 2021 Oct 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Action Potentials/*physiology
CA1 Region, Hippocampal/*physiology
Drinking/*physiology
Pyramidal Cells/*physiology
Saline Solution, Hypertonic/*administration & dosage
Action Potentials/drug effects ; Animals ; CA1 Region, Hippocampal/drug effects ; Drinking/drug effects ; Male ; Pyramidal Cells/drug effects ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Connexin43 hemichannels contribute to working memory and excitatory synaptic transmission of pyramidal neurons in the prefrontal cortex of rats.
Autorzy :
Tao XD; Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain Science, Fudan University, Shanghai 200032, China.
Liu ZR; Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain Science, Fudan University, Shanghai 200032, China.
Zhang YQ; Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain Science, Fudan University, Shanghai 200032, China.
Zhang XH; Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain Science, Fudan University, Shanghai 200032, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Dec 01; Vol. 286, pp. 120049. Date of Electronic Publication: 2021 Oct 15.
Typ publikacji :
Journal Article
MeSH Terms :
Connexin 43/*metabolism
Memory, Short-Term/*physiology
Pyramidal Cells/*metabolism
Animals ; Astrocytes/metabolism ; Brain/metabolism ; Connexin 43/physiology ; Connexins/metabolism ; Gap Junctions/metabolism ; Male ; Memory, Short-Term/drug effects ; Neuronal Plasticity/physiology ; Neurons/drug effects ; Patch-Clamp Techniques/methods ; Prefrontal Cortex/metabolism ; Pyramidal Cells/physiology ; Rats ; Rats, Sprague-Dawley ; Spatial Memory/drug effects ; Synaptic Transmission/drug effects ; Synaptic Transmission/genetics ; Synaptic Transmission/physiology
Czasopismo naukowe
Tytuł :
Photostimulation activates fast-spiking interneurons and pyramidal cells in the entorhinal cortex of Thy1-ChR2-YFP line 18 mice.
Autorzy :
Proskurina EY; Sechenov Institute of Evolutionary Physiology and Biochemistry of RAS, 44, Toreza Prospekt, St. Petersburg, 194223, Russia; Almazov National Medical Research Centre, Institute of Experimental Medicine, 2 Akkuratova Street, St. Petersburg, 197341, Russia. Electronic address: .
Zaitsev AV; Sechenov Institute of Evolutionary Physiology and Biochemistry of RAS, 44, Toreza Prospekt, St. Petersburg, 194223, Russia. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2021 Nov 26; Vol. 580, pp. 87-92. Date of Electronic Publication: 2021 Oct 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Entorhinal Cortex/*physiology
Interneurons/*physiology
Mice/*physiology
Pyramidal Cells/*physiology
Animals ; Bacterial Proteins/genetics ; Carrier Proteins/genetics ; Entorhinal Cortex/radiation effects ; Interneurons/radiation effects ; Light ; Luminescent Proteins/genetics ; Mice/genetics ; Mice, Transgenic ; Optogenetics ; Pyramidal Cells/radiation effects ; Thy-1 Antigens/genetics
Czasopismo naukowe
Tytuł :
Perigenual and Subgenual Anterior Cingulate Afferents Converge on Common Pyramidal Cells in Amygdala Subregions of the Macaque.
Autorzy :
Kelly EA; Department of Neuroscience, University of Rochester, Rochester, New York 14642.
Thomas VK; Department of Pharmacology and Physiology, University of Rochester, Rochester, New York 14642.
Indraghanty A; Department of Neuroscience, University of Rochester, Rochester, New York 14642.
Fudge JL; Department of Neuroscience, University of Rochester, Rochester, New York 14642 .; Department of Psychiatry, University of Rochester, Rochester, New York 14642.
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Źródło :
The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2021 Nov 24; Vol. 41 (47), pp. 9742-9755. Date of Electronic Publication: 2021 Oct 14.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Amygdala/*cytology
Gyrus Cinguli/*cytology
Neural Pathways/*cytology
Neurons, Afferent/*cytology
Pyramidal Cells/*cytology
Amygdala/physiology ; Animals ; Arousal/physiology ; Gyrus Cinguli/physiology ; Macaca fascicularis ; Male ; Neural Pathways/physiology ; Neurons, Afferent/physiology ; Pyramidal Cells/physiology
Czasopismo naukowe
Tytuł :
Genetic dissection of the glutamatergic neuron system in cerebral cortex.
Autorzy :
Matho KS; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, NY, USA.
Huilgol D; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, NY, USA.; Department of Neurobiology, Duke University Medical Center, Durham, NC, USA.
Galbavy W; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, NY, USA.; Program in Neuroscience, Department of Neurobiology and Behavior, Stony Brook University, Stony Brook, NY, USA.
He M; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, NY, USA.; Institutes of Brain Science, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Fudan University, Shanghai, China.
Kim G; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, NY, USA.
An X; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, NY, USA.; Department of Neurobiology, Duke University Medical Center, Durham, NC, USA.
Lu J; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, NY, USA.; Shanghai Jiaotong University Medical School, Shanghai, China.
Wu P; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, NY, USA.
Di Bella DJ; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.
Shetty AS; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.
Palaniswamy R; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, NY, USA.
Hatfield J; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, NY, USA.; Department of Neurobiology, Duke University Medical Center, Durham, NC, USA.
Raudales R; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, NY, USA.; Program in Neuroscience, Department of Neurobiology and Behavior, Stony Brook University, Stony Brook, NY, USA.
Narasimhan A; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, NY, USA.
Gamache E; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, NY, USA.
Levine JM; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, NY, USA.; Program in Neuroscience and Medical Scientist Training Program, Stony Brook University, New York, NY, USA.
Tucciarone J; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, NY, USA.; Program in Neuroscience and Medical Scientist Training Program, Stony Brook University, New York, NY, USA.; Department of Psychiatry, Stanford University School of Medicine, Palo Alto, CA, USA.
Szelenyi E; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, NY, USA.
Harris JA; Program in Neuroscience and Medical Scientist Training Program, Stony Brook University, New York, NY, USA.; Allen Institute for Brain Science, Seattle, WA, USA.
Mitra PP; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, NY, USA.
Osten P; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, NY, USA.
Arlotta P; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Huang ZJ; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, NY, USA. .; Department of Neurobiology, Duke University Medical Center, Durham, NC, USA. .
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Źródło :
Nature [Nature] 2021 Oct; Vol. 598 (7879), pp. 182-187. Date of Electronic Publication: 2021 Oct 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cerebral Cortex/*cytology
Gene Expression Regulation/*genetics
Glutamic Acid/*metabolism
Pyramidal Cells/*cytology
Pyramidal Cells/*metabolism
Animals ; Cell Lineage/genetics ; Cerebral Cortex/metabolism ; Male ; Mice ; Pyramidal Cells/classification ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł :
Conductance-based models and the fragmentation problem: A case study based on hippocampal CA1 pyramidal cell models and epilepsy.
Autorzy :
Tejada J; Departamento de Psicologia, DPS, Universidade Federal de Sergipe, SE 49100-000, Brazil; Facultad de Psicología, Fundación Universitaria Konrad Lorenz, Bogotá, Colombia. Electronic address: .
Roque AC; Departamento de Física, FFCLRP, Universidade de São Paulo, Ribeirão Preto, SP 14040-901, Brazil.
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Źródło :
Epilepsy & behavior : E&B [Epilepsy Behav] 2021 Aug; Vol. 121 (Pt B), pp. 106841. Date of Electronic Publication: 2019 Dec 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Epilepsy, Temporal Lobe*
Pyramidal Cells*
Animals ; Hippocampus ; Humans ; Neurons
Czasopismo naukowe
Tytuł :
Potential of Amantadine to Ameliorate Glutamate-Induced Pyramidal Cells Toxicity in Juvenile Rat' Brain Cortex.
Autorzy :
Ahmed AS; Anatomy and Embryology Department, College of Medicine, Tanta University, Tanta, 31511, Egypt. .
Hantash EM; Anatomy and Embryology Department, College of Medicine, Tanta University, Tanta, 31511, Egypt.
Zakaria SS; Imam Muhammad Bin Saud Islamic University, Riyadh, Saudi Arabia.; Medical Biochemistry and Molecular Biology Department, College of Medicine, Tanta University, Tanta, 31511, Egypt.
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Źródło :
Neurotoxicity research [Neurotox Res] 2021 Aug; Vol. 39 (4), pp. 1203-1210. Date of Electronic Publication: 2021 Apr 23.
Typ publikacji :
Journal Article
MeSH Terms :
Amantadine/*pharmacology
Cerebral Cortex/*drug effects
Glutamic Acid/*toxicity
Pyramidal Cells/*drug effects
Age Factors ; Animals ; Animals, Newborn ; Cerebral Cortex/metabolism ; Cerebral Cortex/pathology ; Dopamine Agents/pharmacology ; Protein Phosphatase 2/metabolism ; Pyramidal Cells/metabolism ; Pyramidal Cells/pathology ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Sex- and subtype-specific adaptations in excitatory signaling onto deep-layer prelimbic cortical pyramidal neurons after chronic alcohol exposure.
Autorzy :
Hughes BA; Department of Psychiatry, University of North Carolina at Chapel Hill, School of Medicine, Chapel Hill, NC, USA. .; Bowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, School of Medicine, Chapel Hill, NC, USA. .
O'Buckley TK; Bowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, School of Medicine, Chapel Hill, NC, USA.
Boero G; Bowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, School of Medicine, Chapel Hill, NC, USA.
Herman MA; Bowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, School of Medicine, Chapel Hill, NC, USA.; Department of Pharmacology, University of North Carolina at Chapel Hill, School of Medicine, Chapel Hill, NC, USA.
Morrow AL; Department of Psychiatry, University of North Carolina at Chapel Hill, School of Medicine, Chapel Hill, NC, USA.; Bowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, School of Medicine, Chapel Hill, NC, USA.; Department of Pharmacology, University of North Carolina at Chapel Hill, School of Medicine, Chapel Hill, NC, USA.
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Źródło :
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology [Neuropsychopharmacology] 2021 Oct; Vol. 46 (11), pp. 1927-1936. Date of Electronic Publication: 2021 May 25.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Prefrontal Cortex*
Pyramidal Cells*
Animals ; Ethanol/toxicity ; Female ; Interneurons ; Male ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Frequency-Dependent Synaptic Dynamics Differentially Tune CA1 and CA2 Pyramidal Neuron Responses to Cortical Input.
Autorzy :
Sun Q; Department of Neuroscience, Kavli Institute for Brain Science, Mortimer B. Zuckerman Mind Brain Behavior Institute, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York 10027 .; Department of Neurosciences, School of Medicine, Case Western Reserve University, Cleveland, Ohio, 44106.
Buss EW; Department of Neuroscience, Kavli Institute for Brain Science, Mortimer B. Zuckerman Mind Brain Behavior Institute, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York 10027.
Jiang YQ; Department of Neurosciences, School of Medicine, Case Western Reserve University, Cleveland, Ohio, 44106.
Santoro B; Department of Neuroscience, Kavli Institute for Brain Science, Mortimer B. Zuckerman Mind Brain Behavior Institute, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York 10027.
Brann DH; Department of Neuroscience, Kavli Institute for Brain Science, Mortimer B. Zuckerman Mind Brain Behavior Institute, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York 10027.
Nicholson DA; Department of Neuroscience, Rush University Medical Center, Chicago, Illinois, 60612.
Siegelbaum SA; Department of Neuroscience, Kavli Institute for Brain Science, Mortimer B. Zuckerman Mind Brain Behavior Institute, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York 10027 .
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Źródło :
The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2021 Sep 29; Vol. 41 (39), pp. 8103-8110. Date of Electronic Publication: 2021 Aug 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
CA1 Region, Hippocampal/*physiology
CA2 Region, Hippocampal/*physiology
Cerebral Cortex/*physiology
Excitatory Postsynaptic Potentials/*physiology
Pyramidal Cells/*physiology
Synapses/*physiology
Animals ; CA1 Region, Hippocampal/drug effects ; CA2 Region, Hippocampal/drug effects ; Cerebral Cortex/drug effects ; Excitatory Postsynaptic Potentials/drug effects ; Female ; GABA-A Receptor Antagonists/pharmacology ; GABA-B Receptor Antagonists/pharmacology ; Male ; Mice ; Neural Pathways/drug effects ; Neural Pathways/physiology ; Patch-Clamp Techniques ; Pyramidal Cells/drug effects ; Synapses/drug effects
Czasopismo naukowe
Tytuł :
All-or-none disconnection of pyramidal inputs onto parvalbumin-positive interneurons gates ocular dominance plasticity.
Autorzy :
Severin D; Mind/Brain Institute, Johns Hopkins University, Baltimore, MD 21218.
Hong SZ; Mind/Brain Institute, Johns Hopkins University, Baltimore, MD 21218.
Roh SE; Department of Neuroscience, Johns Hopkins University, Baltimore, MD 21205.
Huang S; Mind/Brain Institute, Johns Hopkins University, Baltimore, MD 21218.
Zhou J; Department of Neuroscience, Johns Hopkins University, Baltimore, MD 21205.
Bridi MCD; Mind/Brain Institute, Johns Hopkins University, Baltimore, MD 21218.
Hong I; Department of Neuroscience, Johns Hopkins University, Baltimore, MD 21205.
Murase S; Department of Biology, University of Maryland, College Park, MD 20742.
Robertson S; Department of Bioengineering, University of Maryland, College Park, MD 20742.
Haberman RP; Department of Psychological and Brain Sciences, Johns Hopkins University, Baltimore, MD 21218.
Huganir RL; Department of Neuroscience, Johns Hopkins University, Baltimore, MD 21205.
Gallagher M; Department of Bioengineering, University of Maryland, College Park, MD 20742.
Quinlan EM; Department of Biology, University of Maryland, College Park, MD 20742.
Worley P; Department of Neuroscience, Johns Hopkins University, Baltimore, MD 21205.
Kirkwood A; Mind/Brain Institute, Johns Hopkins University, Baltimore, MD 21218; .; Department of Neuroscience, Johns Hopkins University, Baltimore, MD 21205.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Sep 14; Vol. 118 (37).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Dominance, Ocular*
Neural Inhibition*
Neuronal Plasticity*
Interneurons/*physiology
Parvalbumins/*metabolism
Pyramidal Cells/*physiology
Visual Cortex/*physiology
Animals ; C-Reactive Protein/metabolism ; Interneurons/cytology ; Mice ; Mice, Inbred C57BL ; Nerve Tissue Proteins/metabolism ; Pyramidal Cells/cytology ; Receptors, AMPA/metabolism ; Receptors, N-Methyl-D-Aspartate/metabolism
Czasopismo naukowe
Tytuł :
Remifentanil self-administration in mice promotes sex-specific prefrontal cortex dysfunction underlying deficits in cognitive flexibility.
Autorzy :
Anderson EM; Department of Biomedical Sciences, Marquette University, Milwaukee, WI, 53233, USA.
Engelhardt A; Department of Biomedical Sciences, Marquette University, Milwaukee, WI, 53233, USA.
Demis S; Department of Biomedical Sciences, Marquette University, Milwaukee, WI, 53233, USA.
Porath E; Department of Biomedical Sciences, Marquette University, Milwaukee, WI, 53233, USA.
Hearing MC; Department of Biomedical Sciences, Marquette University, Milwaukee, WI, 53233, USA. .
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Źródło :
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology [Neuropsychopharmacology] 2021 Sep; Vol. 46 (10), pp. 1734-1745. Date of Electronic Publication: 2021 May 19.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Prefrontal Cortex*
Pyramidal Cells*
Animals ; Cognition ; Female ; Male ; Mice ; Remifentanil ; Synaptic Transmission
Czasopismo naukowe
Tytuł :
Single cortical neurons as deep artificial neural networks.
Autorzy :
Beniaguev D; Edmond and Lily Safra Center for Brain Sciences (ELSC), The Hebrew University of Jerusalem, Jerusalem 91904, Israel. Electronic address: .
Segev I; Edmond and Lily Safra Center for Brain Sciences (ELSC), The Hebrew University of Jerusalem, Jerusalem 91904, Israel; Department of Neurobiology, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.
London M; Edmond and Lily Safra Center for Brain Sciences (ELSC), The Hebrew University of Jerusalem, Jerusalem 91904, Israel; Department of Neurobiology, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.
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Źródło :
Neuron [Neuron] 2021 Sep 01; Vol. 109 (17), pp. 2727-2739.e3. Date of Electronic Publication: 2021 Aug 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Deep Learning*
Models, Neurological*
Cerebral Cortex/*physiology
Pyramidal Cells/*physiology
Cerebral Cortex/cytology ; Cerebral Cortex/metabolism ; Dendrites/metabolism ; Dendrites/physiology ; Humans ; Pyramidal Cells/metabolism ; Receptors, N-Methyl-D-Aspartate/metabolism
Czasopismo naukowe
Tytuł :
Increased levels of α4-containing GABA A receptors in focal cortical dysplasia: A possible cause of benzodiazepine resistance.
Autorzy :
Sharma D; Department of Neurosurgery, All India Institute of Medical Sciences, New Delhi, India. Electronic address: .
Dixit AB; Dr. B.R Ambedkar Center for Biomedical Research, University of Delhi, New Delhi, India. Electronic address: .
Dey S; Department of Neurosurgery, All India Institute of Medical Sciences, New Delhi, India. Electronic address: .
Tripathi M; Department of Neurology, All India Institute of Medical Sciences, New Delhi, India. Electronic address: .
Doddamani R; Department of Neurosurgery, All India Institute of Medical Sciences, New Delhi, India. Electronic address: .
Sharma MC; Department of Pathology, All India Institute of Medical Sciences, New Delhi, India. Electronic address: .
Lalwani S; Department of Forensic Medicine and Toxicology, All India Institute of Medical Sciences, New Delhi, India. Electronic address: .
Gurjar HK; Department of Neurosurgery, All India Institute of Medical Sciences, New Delhi, India. Electronic address: .
Chandra PS; Department of Neurosurgery, All India Institute of Medical Sciences, New Delhi, India. Electronic address: .
Banerjee J; Department of Biophysics, All India Institute of Medical Sciences, New Delhi, India. Electronic address: .
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Źródło :
Neurochemistry international [Neurochem Int] 2021 Sep; Vol. 148, pp. 105084. Date of Electronic Publication: 2021 May 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Benzodiazepines/*pharmacology
Pyramidal Cells/*drug effects
Receptors, GABA-A/*drug effects
Adolescent ; Adult ; Aged ; Child ; Drug Resistant Epilepsy/drug therapy ; Female ; Hippocampus/drug effects ; Hippocampus/metabolism ; Humans ; Male ; Middle Aged ; Pyramidal Cells/metabolism ; Receptors, GABA-A/metabolism ; Young Adult ; gamma-Aminobutyric Acid/metabolism
Czasopismo naukowe
Tytuł :
Impact of gyral geometry on cortical responses to surface electrical stimulation: insights from experimental and modeling studies.
Autorzy :
Kudela P; Department of Neurosurgery, Johns Hopkins University School of Medicine, Meyer 8-181, 600 North Wolfe St, Baltimore, MD 21287, United States of America.
Anderson WS; Department of Neurosurgery, Johns Hopkins University School of Medicine, Meyer 8-181, 600 North Wolfe St, Baltimore, MD 21287, United States of America.
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Źródło :
Journal of neural engineering [J Neural Eng] 2021 Aug 31; Vol. 18 (4). Date of Electronic Publication: 2021 Aug 31.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Neurons*
Pyramidal Cells*
Axons ; Electric Stimulation ; Humans
Czasopismo naukowe
Tytuł :
In Vivo Calcium Imaging of CA3 Pyramidal Neuron Populations in Adult Mouse Hippocampus.
Autorzy :
Schoenfeld G; Laboratory of Neural Circuit Dynamics, Brain Research Institute, University of Zurich, Zurich CH-8057, Switzerland.; Neuroscience Center Zurich, University of Zurich, Zurich CH-8057, Switzerland.
Carta S; Laboratory of Neural Circuit Dynamics, Brain Research Institute, University of Zurich, Zurich CH-8057, Switzerland.; Neuroscience Center Zurich, University of Zurich, Zurich CH-8057, Switzerland.
Rupprecht P; Laboratory of Neural Circuit Dynamics, Brain Research Institute, University of Zurich, Zurich CH-8057, Switzerland.
Ayaz A; Laboratory of Neural Circuit Dynamics, Brain Research Institute, University of Zurich, Zurich CH-8057, Switzerland.; Neuroscience Center Zurich, University of Zurich, Zurich CH-8057, Switzerland.
Helmchen F; Laboratory of Neural Circuit Dynamics, Brain Research Institute, University of Zurich, Zurich CH-8057, Switzerland .; Neuroscience Center Zurich, University of Zurich, Zurich CH-8057, Switzerland.
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Źródło :
ENeuro [eNeuro] 2021 Aug 23; Vol. 8 (4). Date of Electronic Publication: 2021 Aug 23 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcium*
Pyramidal Cells*
Action Potentials ; Animals ; Hippocampus ; Humans ; Mice ; Neurons
Czasopismo naukowe
Tytuł :
BiPOLES is an optogenetic tool developed for bidirectional dual-color control of neurons.
Autorzy :
Vierock J; Institute for Biology, Experimental Biophysics, Humboldt University Berlin, Berlin, Germany.
Rodriguez-Rozada S; Research Group Synaptic Wiring and Information Processing, Center for Molecular Neurobiology Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Dieter A; Research Group Synaptic Wiring and Information Processing, Center for Molecular Neurobiology Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Pieper F; Department of Neurophysiology and Pathophysiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Sims R; Wavefront-Engineering Microscopy Group, Photonics Department, Institut de la Vision, Sorbonne Université, INSERM, CNRS, Institut de la Vision, Paris, France.
Tenedini F; Research Group Neuronal Patterning and Connectivity, Center for Molecular Neurobiology Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Bergs ACF; Buchmann Institute for Molecular Life Sciences and Institute of Biophysical Chemistry, Goethe University, Frankfurt, Germany.
Bendifallah I; Wavefront-Engineering Microscopy Group, Photonics Department, Institut de la Vision, Sorbonne Université, INSERM, CNRS, Institut de la Vision, Paris, France.
Zhou F; Research Group Neuronal Patterning and Connectivity, Center for Molecular Neurobiology Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Zeitzschel N; Buchmann Institute for Molecular Life Sciences and Institute of Biophysical Chemistry, Goethe University, Frankfurt, Germany.
Ahlbeck J; Department of Neurophysiology and Pathophysiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Augustin S; Institute for Biology, Experimental Biophysics, Humboldt University Berlin, Berlin, Germany.
Sauter K; Research Group Synaptic Wiring and Information Processing, Center for Molecular Neurobiology Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Research Group Neuronal Patterning and Connectivity, Center for Molecular Neurobiology Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Papagiakoumou E; Wavefront-Engineering Microscopy Group, Photonics Department, Institut de la Vision, Sorbonne Université, INSERM, CNRS, Institut de la Vision, Paris, France.
Gottschalk A; Buchmann Institute for Molecular Life Sciences and Institute of Biophysical Chemistry, Goethe University, Frankfurt, Germany.
Soba P; Research Group Neuronal Patterning and Connectivity, Center for Molecular Neurobiology Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; LIMES Institute, University of Bonn, Bonn, Germany.
Emiliani V; Wavefront-Engineering Microscopy Group, Photonics Department, Institut de la Vision, Sorbonne Université, INSERM, CNRS, Institut de la Vision, Paris, France.
Engel AK; Department of Neurophysiology and Pathophysiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Hegemann P; Institute for Biology, Experimental Biophysics, Humboldt University Berlin, Berlin, Germany.
Wiegert JS; Research Group Synaptic Wiring and Information Processing, Center for Molecular Neurobiology Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. .
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Źródło :
Nature communications [Nat Commun] 2021 Jul 26; Vol. 12 (1), pp. 4527. Date of Electronic Publication: 2021 Jul 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Membrane/*physiology
Opsins/*metabolism
Optogenetics/*methods
Pyramidal Cells/*physiology
Animals ; Caenorhabditis elegans/genetics ; Caenorhabditis elegans/metabolism ; Cells, Cultured ; Drosophila melanogaster/genetics ; Drosophila melanogaster/metabolism ; Female ; Ferrets/genetics ; Ferrets/metabolism ; HEK293 Cells ; Hippocampus/cytology ; Humans ; Male ; Membrane Potentials/physiology ; Mice, Transgenic ; Opsins/genetics ; Patch-Clamp Techniques/methods ; Pyramidal Cells/cytology ; Pyramidal Cells/metabolism ; Rats, Wistar ; Reproducibility of Results
Czasopismo naukowe
Tytuł :
Kainate-Induced Degeneration of Hippocampal Neurons. Protective Effect of Activation of the Endocannabinoid System.
Autorzy :
Gordon RY; Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Moscow region, Russia. .
Mikheeva IB; Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow region, Russia.
Shubina LV; Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow region, Russia.
Khutsian SS; Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Moscow region, Russia.
Kitchigina VF; Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow region, Russia.
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Źródło :
Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2021 Jul; Vol. 171 (3), pp. 327-332. Date of Electronic Publication: 2021 Jul 23.
Typ publikacji :
Journal Article
MeSH Terms :
Arachidonic Acids/*metabolism
Endocannabinoids/*metabolism
Excitatory Amino Acid Agonists/*pharmacology
Kainic Acid/*pharmacology
Nerve Degeneration/*pathology
Polyunsaturated Alkamides/*metabolism
Pyramidal Cells/*drug effects
Status Epilepticus/*pathology
Animals ; Autophagosomes/drug effects ; Autophagosomes/metabolism ; Autophagosomes/ultrastructure ; Benzamides/pharmacology ; CA3 Region, Hippocampal/drug effects ; CA3 Region, Hippocampal/metabolism ; CA3 Region, Hippocampal/pathology ; Carbamates/pharmacology ; Dentate Gyrus/drug effects ; Dentate Gyrus/metabolism ; Dentate Gyrus/pathology ; Endoplasmic Reticulum/drug effects ; Endoplasmic Reticulum/metabolism ; Endoplasmic Reticulum/ultrastructure ; Golgi Apparatus/drug effects ; Golgi Apparatus/metabolism ; Golgi Apparatus/ultrastructure ; Lysosomes/drug effects ; Lysosomes/metabolism ; Lysosomes/ultrastructure ; Male ; Microscopy, Electron ; Necrosis/metabolism ; Necrosis/pathology ; Nerve Degeneration/chemically induced ; Nerve Degeneration/metabolism ; Pyramidal Cells/metabolism ; Pyramidal Cells/pathology ; Rats ; Rats, Wistar ; Status Epilepticus/chemically induced ; Status Epilepticus/metabolism
Czasopismo naukowe
Tytuł :
Dose-dependent effects of prenatal exposure of pioglitazone, the PPARγ agonist, on the hippocampus development and learning and memory performance of rat offspring.
Autorzy :
Sağır D; Faculty of Health Sciences, Sinop University, 57000 Sinop, Turkey. Electronic address: .
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Źródło :
Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2021 Jun 15; Vol. 421, pp. 115544. Date of Electronic Publication: 2021 Apr 21.
Typ publikacji :
Journal Article
MeSH Terms :
Prenatal Exposure Delayed Effects*
Behavior, Animal/*drug effects
Hippocampus/*drug effects
Learning/*drug effects
PPAR gamma/*agonists
Pioglitazone/*toxicity
Pyramidal Cells/*drug effects
Animals ; Dose-Response Relationship, Drug ; Female ; Gestational Age ; Glial Fibrillary Acidic Protein/metabolism ; Hippocampus/metabolism ; Hippocampus/physiopathology ; Memory/drug effects ; Morris Water Maze Test/drug effects ; Neuroglia/drug effects ; Neuroglia/metabolism ; Neuroglia/pathology ; PPAR gamma/metabolism ; Pregnancy ; Pyramidal Cells/metabolism ; Pyramidal Cells/pathology ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Control of impulsivity by G i -protein signalling in layer-5 pyramidal neurons of the anterior cingulate cortex.
Autorzy :
van der Veen B; Institute of Applied Physiology, Ulm University, Ulm, Germany.
Kapanaiah SKT; Institute of Applied Physiology, Ulm University, Ulm, Germany.
Kilonzo K; Institute of Applied Physiology, Ulm University, Ulm, Germany.
Steele-Perkins P; Institute of Applied Physiology, Ulm University, Ulm, Germany.
Jendryka MM; Institute of Applied Physiology, Ulm University, Ulm, Germany.
Schulz S; Institute of Applied Physiology, Ulm University, Ulm, Germany.
Tasic B; Allen Institute for Brain Science, Seattle, WA, USA.
Yao Z; Allen Institute for Brain Science, Seattle, WA, USA.
Zeng H; Allen Institute for Brain Science, Seattle, WA, USA.
Akam T; Department of Experimental Psychology, University of Oxford, Oxford, UK.
Nicholson JR; Boehringer Ingelheim Pharma GmbH & Co. KG, Div. Research Germany, Biberach an der Riss, Germany.
Liss B; Institute of Applied Physiology, Ulm University, Ulm, Germany.; Linacre College and New College, University of Oxford, Oxford, UK.
Nissen W; Boehringer Ingelheim Pharma GmbH & Co. KG, Div. Research Germany, Biberach an der Riss, Germany.
Pekcec A; Boehringer Ingelheim Pharma GmbH & Co. KG, Div. Research Germany, Biberach an der Riss, Germany.
Kätzel D; Institute of Applied Physiology, Ulm University, Ulm, Germany. .
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Źródło :
Communications biology [Commun Biol] 2021 Jun 02; Vol. 4 (1), pp. 662. Date of Electronic Publication: 2021 Jun 02.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
GTP-Binding Protein alpha Subunits, Gi-Go/*physiology
Gyrus Cinguli/*cytology
Gyrus Cinguli/*physiology
Pyramidal Cells/*physiology
Animals ; Clozapine/analogs & derivatives ; Clozapine/pharmacology ; Female ; GTP-Binding Protein alpha Subunits, Gi-Go/drug effects ; GTP-Binding Protein alpha Subunits, Gi-Go/genetics ; Gene Expression/drug effects ; Gyrus Cinguli/drug effects ; Humans ; Impulsive Behavior/drug effects ; Impulsive Behavior/physiology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mice, Transgenic ; Pyramidal Cells/cytology ; Pyramidal Cells/drug effects ; Receptors, Metabotropic Glutamate/drug effects ; Receptors, Metabotropic Glutamate/genetics ; Receptors, Metabotropic Glutamate/physiology ; Signal Transduction
Czasopismo naukowe
Tytuł :
I CAN (TRPM4) Contributes to the Intrinsic Excitability of Prefrontal Cortex Layer 2/3 Pyramidal Neurons.
Autorzy :
Riquelme D; Department of Biology, Faculty of Chemistry and Biology, Universidad de Santiago de Chile, Santiago 9170002, Chile.
Peralta FA; Department of Biology, Faculty of Chemistry and Biology, Universidad de Santiago de Chile, Santiago 9170002, Chile.
Navarro FD; Department of Biology, Faculty of Chemistry and Biology, Universidad de Santiago de Chile, Santiago 9170002, Chile.
Moreno C; Department of Biology, Faculty of Chemistry and Biology, Universidad de Santiago de Chile, Santiago 9170002, Chile.
Leiva-Salcedo E; Department of Biology, Faculty of Chemistry and Biology, Universidad de Santiago de Chile, Santiago 9170002, Chile.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 May 17; Vol. 22 (10). Date of Electronic Publication: 2021 May 17.
Typ publikacji :
Journal Article
MeSH Terms :
Prefrontal Cortex/*metabolism
Pyramidal Cells/*metabolism
TRPM Cation Channels/*metabolism
Action Potentials/physiology ; Animals ; Calcium/metabolism ; Male ; Membrane Potentials/physiology ; Mice ; Mice, Inbred C57BL ; Patch-Clamp Techniques ; Prefrontal Cortex/drug effects ; Pyramidal Cells/drug effects ; Pyramidal Cells/pathology ; TRPM Cation Channels/physiology
Czasopismo naukowe

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