Temat: "Pyridines" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Identification of differentially expressed mRNA/lncRNA modules in acutely regorafenib-treated sorafenib-resistant Huh7 hepatocellular carcinoma cells.
Autorzy:: Baek M; Department of Molecular and Life Science, Hanyang University, Ansan, Republic of Korea.
Kim M; Department of Molecular and Life Science, Hanyang University, Ansan, Republic of Korea.
Choi HI; Department of Molecular and Life Science, Hanyang University, Ansan, Republic of Korea.
Binas B; Department of Molecular and Life Science, Hanyang University, Ansan, Republic of Korea.
Cha J; Department of Applied Artificial Intelligence, Hanyang University, Ansan, Republic of Korea.
Jung KH; Department of Biopharmaceutical System, Gwangmyeong Convergence Technology Campus of Korea Polytechnic II, Incheon, Republic of Korea.
Choi S; Department of Applied Artificial Intelligence, Hanyang University, Ansan, Republic of Korea.; Department of Mathematical Data Science, Hanyang University, Ansan, Republic of Korea.
Chai YG; Department of Molecular and Life Science, Hanyang University, Ansan, Republic of Korea.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2024 Apr 11; Vol. 19 (4), pp. e0301663. Date of Electronic Publication: 2024 Apr 11 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Carcinoma, Hepatocellular*/drug therapy
Carcinoma, Hepatocellular*/genetics
Carcinoma, Hepatocellular*/pathology
RNA, Long Noncoding*/genetics
Liver Neoplasms*/drug therapy
Liver Neoplasms*/genetics
Liver Neoplasms*/metabolism
Phenylurea Compounds*
Pyridines*
Humans ; Sorafenib/pharmacology ; Proto-Oncogene Proteins c-akt/metabolism ; Phosphatidylinositol 3-Kinases ; RNA, Messenger/metabolism ; Transforming Growth Factor beta

Czasopismo naukowe

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Skocz do pozycji: 2.

Tytuł:: Evaluation of models to predict prognosis in patients with advanced hepatocellular carcinoma treated with TACE combined with apatinib.
Autorzy:: Sun F; Department of Radiology, Anhui Provincial Hospital of Anhui Medical University, Hefei, China.
Liu KC; Infection Hospital(Hefei Infectious Disease Hospital), The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Ul Ain Q; The First Affiliated Hospital of University of Science and Technology of China, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China, China.
Lu D; Department of Radiology, The First Affiliated Hospital of University of Science and Technology of China (USTC), Division of Life Sciences and Medicine, University of Science and Technology of China, 230000, Hefei, China.
Zhou CZ; Department of Radiology, The First Affiliated Hospital of University of Science and Technology of China (USTC), Division of Life Sciences and Medicine, University of Science and Technology of China, 230000, Hefei, China.
Xiao JK; Department of Radiology, The First Affiliated Hospital of University of Science and Technology of China (USTC), Division of Life Sciences and Medicine, University of Science and Technology of China, 230000, Hefei, China.
Zhang XM; Department of Radiology, The First Affiliated Hospital of University of Science and Technology of China (USTC), Division of Life Sciences and Medicine, University of Science and Technology of China, 230000, Hefei, China.
Zhang ZF; Department of Radiology, The First Affiliated Hospital of University of Science and Technology of China (USTC), Division of Life Sciences and Medicine, University of Science and Technology of China, 230000, Hefei, China.
Cheng DL; Department of Radiology, The First Affiliated Hospital of University of Science and Technology of China (USTC), Division of Life Sciences and Medicine, University of Science and Technology of China, 230000, Hefei, China.
He YS; Department of Radiology, The First Affiliated Hospital of University of Science and Technology of China (USTC), Division of Life Sciences and Medicine, University of Science and Technology of China, 230000, Hefei, China. .
Lv WF; Department of Radiology, Anhui Provincial Hospital of Anhui Medical University, Hefei, China. .; Department of Radiology, The First Affiliated Hospital of University of Science and Technology of China (USTC), Division of Life Sciences and Medicine, University of Science and Technology of China, 230000, Hefei, China. .; Pokaż więcej
Źródło:: BMC gastroenterology [BMC Gastroenterol] 2024 Apr 08; Vol. 24 (1), pp. 129. Date of Electronic Publication: 2024 Apr 08.
Typ publikacji:: Journal Article
MeSH Terms:: Carcinoma, Hepatocellular*/pathology
Liver Neoplasms*/pathology
Chemoembolization, Therapeutic*/methods
Pyridines*
Humans ; Retrospective Studies ; Prognosis

Czasopismo naukowe

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Skocz do pozycji: 3.

Tytuł:: Impact of improved dead time correction on the quantification accuracy of a dedicated BrainPET scanner.
Autorzy:: Issa ASM; Institute of Neuroscience and Medicine 4, INM-4, Forschungszentrum Jülich, Jülich, Germany.; JARA, BRAIN, Translational Medicine, Aachen, Germany.; Department of Neurology, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
Scheins J; Institute of Neuroscience and Medicine 4, INM-4, Forschungszentrum Jülich, Jülich, Germany.
Tellmann L; Institute of Neuroscience and Medicine 4, INM-4, Forschungszentrum Jülich, Jülich, Germany.
Brambilla CR; Institute of Neuroscience and Medicine 4, INM-4, Forschungszentrum Jülich, Jülich, Germany.
Lohmann P; Institute of Neuroscience and Medicine 4, INM-4, Forschungszentrum Jülich, Jülich, Germany.
Rota-Kops E; Institute of Neuroscience and Medicine 4, INM-4, Forschungszentrum Jülich, Jülich, Germany.
Herzog H; Institute of Neuroscience and Medicine 4, INM-4, Forschungszentrum Jülich, Jülich, Germany.
Neuner I; Institute of Neuroscience and Medicine 4, INM-4, Forschungszentrum Jülich, Jülich, Germany.; JARA, BRAIN, Translational Medicine, Aachen, Germany.; Department of Psychiatry, Psychotherapy and Psychosomatics, RWTH Aachen University, Aachen, Germany.
Shah NJ; Institute of Neuroscience and Medicine 4, INM-4, Forschungszentrum Jülich, Jülich, Germany.; JARA, BRAIN, Translational Medicine, Aachen, Germany.; Department of Neurology, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.; Institute of Neuroscience and Medicine 11, INM-11, JARA, Forschungszentrum Jülich, Jülich, Germany.
Lerche C; Institute of Neuroscience and Medicine 4, INM-4, Forschungszentrum Jülich, Jülich, Germany.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2024 Apr 05; Vol. 19 (4), pp. e0296357. Date of Electronic Publication: 2024 Apr 05 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Positron-Emission Tomography*/methods
Brain*/diagnostic imaging
Brain*/blood supply
Oximes*
Pyridines*
Phantoms, Imaging ; Head ; Magnetic Resonance Imaging

Czasopismo naukowe

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Skocz do pozycji: 4.

Tytuł:: Comparing Safety and Efficacy of TACE + Apatinib in Combination with a PD-1 Inhibitor versus a Non-triple Therapy for Treating Advanced Primary Hepatocellular Carcinoma: A Systematic Review and Meta-analysis.
Autorzy:: Pan D; Department of Oncology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou，China. .
Liu H; Department of Oncology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China. .
Qu P; Department of Gastroenterology, The second Affiliated Hospital of Xuzhou Medical University, Jiangsu, China. .
Chen X; Department of Oncology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China. .
Ma X; Department of Oncology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China. .
Wang Y; Department of General Surgery, The Affiliated Hospital of Xuzhou Medical University, Jiangsu, China. .
Qin X; Department of Oncology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China. qin_.
Han Z; Department of Oncology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China. .; Pokaż więcej
Źródło:: Journal of gastrointestinal and liver diseases : JGLD [J Gastrointestin Liver Dis] 2024 Mar 30; Vol. 33 (1), pp. 85-93. Date of Electronic Publication: 2024 Mar 30.
Typ publikacji:: Comparative Study; Meta-Analysis; Systematic Review
MeSH Terms:: Antineoplastic Agents*/adverse effects
Carcinoma, Hepatocellular*/pathology
Chemoembolization, Therapeutic*/methods
Liver Neoplasms*/drug therapy
Liver Neoplasms*/pathology
Pyridines*
Humans ; Combined Modality Therapy ; Immune Checkpoint Inhibitors

Raport

na półce

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Skocz do pozycji: 5.

Tytuł:: Camptothecin enhances the anti-tumor effect of low-dose apatinib combined with PD-1 inhibitor on hepatocellular carcinoma.
Autorzy:: Wang H; Department of Radiology, The First Affiliated Hospital of Shandong First Medical University, Jinan, Shandong, 250000, People's Republic of China.
Gao C; Jinan Center for Disease Control and Prevention, Jinan, Shandong, 250000, People's Republic of China.
Li X; Department of Radiology, The First Affiliated Hospital of Shandong First Medical University, Jinan, Shandong, 250000, People's Republic of China.
Chen F; Department of Radiology, The First Affiliated Hospital of Shandong First Medical University, Jinan, Shandong, 250000, People's Republic of China. .; Department of Radiology, The First Affiliated Hospital of Shandong First Medical University and Shandong Provincial Qianfoshan Hospital, 16766 Jingshi Road, Lixia, Jinan, Shandong, 250014, People's Republic of China. .
Li G; Department of Radiology, The First Affiliated Hospital of Shandong First Medical University and Shandong Provincial Qianfoshan Hospital, 16766 Jingshi Road, Lixia, Jinan, Shandong, 250014, People's Republic of China. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Mar 26; Vol. 14 (1), pp. 7140. Date of Electronic Publication: 2024 Mar 26.
Typ publikacji:: Journal Article
MeSH Terms:: Carcinoma, Hepatocellular*/pathology
Liver Neoplasms*/pathology
Pyridines*
Animals ; Mice ; Vascular Endothelial Growth Factor A/metabolism ; B7-H1 Antigen/metabolism ; Immune Checkpoint Inhibitors/therapeutic use ; Programmed Cell Death 1 Receptor/metabolism ; NF-E2-Related Factor 2 ; Camptothecin/therapeutic use ; Cell Line, Tumor

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Skocz do pozycji: 6.

Tytuł:: The safety and efficacy of clevidipine for blood pressure management in neurocritical patients: a systematic review and meta-analysis.
Autorzy:: Widiastuti M; Department of Anesthesiology, Universitas Padjajaran, Bandung, West Java, Indonesia. .; Department of Anesthesiology, Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Banten, Indonesia. .; Department of Anesthesiology, Siloam Hospital Lippo Village, Tangerang, Banten, Indonesia. .
Bisri DY; Department of Anesthesiology, Universitas Padjajaran, Bandung, West Java, Indonesia.
Rachman IA; Department of Anesthesiology, Universitas Padjajaran, Bandung, West Java, Indonesia.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Mar 16; Vol. 14 (1), pp. 6355. Date of Electronic Publication: 2024 Mar 16.
Typ publikacji:: Meta-Analysis; Systematic Review; Journal Article
MeSH Terms:: Antihypertensive Agents*/adverse effects
Hypertension*/drug therapy
Pyridines*
Humans ; Blood Pressure ; Calcium Channel Blockers/adverse effects ; Retrospective Studies ; Treatment Outcome

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Skocz do pozycji: 7.

Tytuł:: Exploring Regorafenib Responsiveness and Uncovering Molecular Mechanisms in Recurrent Glioblastoma Tumors through Longitudinal In Vitro Sampling.
Autorzy:: Morelli M; Fondazione Pisana per la Scienza, San Giuliano Terme, 56017 Pisa, Italy.
Lessi F; Fondazione Pisana per la Scienza, San Giuliano Terme, 56017 Pisa, Italy.
Franceschi S; Fondazione Pisana per la Scienza, San Giuliano Terme, 56017 Pisa, Italy.
Ferri G; Fondazione Pisana per la Scienza, San Giuliano Terme, 56017 Pisa, Italy.
Giacomarra M; Fondazione Pisana per la Scienza, San Giuliano Terme, 56017 Pisa, Italy.
Menicagli M; Fondazione Pisana per la Scienza, San Giuliano Terme, 56017 Pisa, Italy.
Gambacciani C; Neurosurgical Department of Spedali Riuniti di Livorno, 57124 Livorno, Italy.
Pieri F; Neurosurgical Department of Spedali Riuniti di Livorno, 57124 Livorno, Italy.
Pasqualetti F; Radiotherapy Department, Azienda Ospedaliera Universitaria Pisana, 56126 Pisa, Italy.
Montemurro N; Department of Neurosurgery, Azienda Ospedaliera Universitaria Pisana, 56126 Pisa, Italy.
Aretini P; Fondazione Pisana per la Scienza, San Giuliano Terme, 56017 Pisa, Italy.
Santonocito OS; Neurosurgical Department of Spedali Riuniti di Livorno, 57124 Livorno, Italy.
Di Stefano AL; Neurosurgical Department of Spedali Riuniti di Livorno, 57124 Livorno, Italy.
Mazzanti CM; Fondazione Pisana per la Scienza, San Giuliano Terme, 56017 Pisa, Italy.; Pokaż więcej
Źródło:: Cells [Cells] 2024 Mar 11; Vol. 13 (6). Date of Electronic Publication: 2024 Mar 11.
Typ publikacji:: Journal Article
MeSH Terms:: Glioblastoma*/drug therapy
Glioblastoma*/pathology
Phenylurea Compounds*
Pyridines*
Humans ; Antineoplastic Agents, Alkylating/pharmacology ; Neoplasm Recurrence, Local/pathology ; Temozolomide/pharmacology

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Skocz do pozycji: 8.

Tytuł:: Effects of thienopyridine class antiplatelets on bleeding outcomes following robot-assisted radical prostatectomy.
Autorzy:: Kubota M; Department of Urology, Kyoto University Graduate School of Medicine, Kyoto, Japan.; Department of Urology, Kobe City Medical Center General Hospital, Kobe, Hyogo, Japan.; Department of Pharmacoepidemiology, Graduate School of Medicine and Public Health, Kyoto University, Kyoto, Japan.
Kawakita M; Department of Urology, Kobe City Medical Center General Hospital, Kobe, Hyogo, Japan.
Yoshida S; Department of Pharmacoepidemiology, Graduate School of Medicine and Public Health, Kyoto University, Kyoto, Japan.
Kimura H; Department of Urology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Sumiyoshi T; Department of Urology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Yamasaki T; Department of Urology, Kobe City Medical Center General Hospital, Kobe, Hyogo, Japan.
Okumura K; Department of Urology, Tenri Yorozu Hospital, Nara, Japan.
Yoshimura K; Department of Urology, Shizuoka General Hospital, Shizuoka, Japan.
Matsui Y; Department of Urology, National Cancer Center Hospital, Tokyo, Japan.
Sugiyama K; Department of Urology, Kurashiki Central Hospital, Okayama, Japan.
Okuno H; Department of Urology, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.
Segawa T; Department of Urology, Kyoto City Hospital, Kyoto, Japan.
Shimizu Y; Department of Urology, Kobe City Nishi-Kobe Medical Center, Kobe, Hyogo, Japan.
Ito N; Department of Urology, Japanese Red Cross Wakayama Medical Center, Wakayama, Japan.
Onishi H; Department of Urology, Japanese Red Cross Osaka Hospital, Osaka, Japan.
Ishitoya S; Department of Urology, Japanese Red Cross Otsu Hospital, Otsu, Shiga, Japan.
Soda T; Department of Urology, Kitano Hospital, Osaka, Japan.
Yoshida T; Department of Urology, Shiga General Hospital, Moriyama, Shiga, Japan.
Uemura Y; Department of Urology, Toyooka Hospital, Toyooka, Hyogo, Japan.
Iwamura H; Department of Urology, Himeji Medical Center, Himeji, Hyogo, Japan.
Okubo K; Department of Urology, Kyoto Katsura Hospital, Kyoto, Japan.
Suzuki R; Department of Urology, Numazu City Hospital, Shizuoka, Japan.
Fukuzawa S; Department of Urology, Shimada General Medical Center, Shizuoka, Japan.
Akao T; Department of Urology, Rakuwakai Otowa Hospital, Kyoto, Japan.
Kurahashi R; Department of Urology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
Shimatani K; Department of Urology, Hyogo Medical University, Nishinomiya, Hyogo, Japan.
Sekine Y; Department of Urology, Akita University Graduate School of Medicine, Akita, Japan.
Negoro H; Department of Urology, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Akamatsu S; Department of Urology, Nagoya University, Nagoya, Aichi, Japan.
Kamoto T; Department of Urology, Miyazaki University, Miyazaki, Japan.
Ogawa O; Department of Urology, Kyoto University Graduate School of Medicine, Kyoto, Japan.; Department of Urology, Japanese Red Cross Otsu Hospital, Otsu, Shiga, Japan.
Kawakami K; Department of Pharmacoepidemiology, Graduate School of Medicine and Public Health, Kyoto University, Kyoto, Japan.
Kobayashi T; Department of Urology, Kyoto University Graduate School of Medicine, Kyoto, Japan. .
Goto T; Department of Urology, Kyoto University Graduate School of Medicine, Kyoto, Japan.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Mar 11; Vol. 14 (1), pp. 5847. Date of Electronic Publication: 2024 Mar 11.
Typ publikacji:: Journal Article
MeSH Terms:: Platelet Aggregation Inhibitors*/adverse effects
Robotics*
Pyridines*
Male ; Humans ; Cohort Studies ; Hemorrhage/chemically induced ; Aspirin/adverse effects ; Thienopyridines ; Prostatectomy/adverse effects

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na półce

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Skocz do pozycji: 9.

Tytuł:: Electrolyte disorders induced by six multikinase inhibitors therapy for renal cell carcinoma: a large-scale pharmacovigilance analysis.
Autorzy:: She X; Department of Pharmacy, Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, People's Republic of China.
Yin D; Department of Pharmacy, Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, People's Republic of China.
Guo Q; Department of Pharmacy, Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, People's Republic of China.
Tang Y; Department of Pharmacy, School of Pharmacy, Shanxi Medical University, Taiyuan, Shanxi, People's Republic of China.
Wang S; Department of Pharmacy, Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, People's Republic of China. .
Wang X; Central Laboratory, Shanxi Hospital of Integrated Traditional Chinese and Western Medicine, Taiyuan, Shanxi, People's Republic of China. .; Key Laboratory of Research and Development of Traditional Chinese Medicine Preparations, Taiyuan, Shanxi, People's Republic of China. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Mar 07; Vol. 14 (1), pp. 5592. Date of Electronic Publication: 2024 Mar 07.
Typ publikacji:: Journal Article; Observational Study
MeSH Terms:: Anilides*
Carcinoma, Renal Cell*/drug therapy
Indazoles*
Kidney Neoplasms*/pathology
Phenylurea Compounds*
Pyridines*
Pyrimidines*
Quinolines*
Sulfonamides*
Aged ; Humans ; Male ; Axitinib/therapeutic use ; Bayes Theorem ; Electrolytes ; Pharmacovigilance ; Retrospective Studies ; Sorafenib/adverse effects ; Sunitinib/adverse effects ; United States ; United States Food and Drug Administration ; Female ; Middle Aged

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Skocz do pozycji: 10.

Tytuł:: A first survey for herbicide resistant weeds across major maize growing areas in the North Island of New Zealand.
Autorzy:: Ngow Z; AgResearch Ltd., Ruakura Research Centre, Hamilton, New Zealand.
James TK; AgResearch Ltd., Ruakura Research Centre, Hamilton, New Zealand.
Harvey B; Foundation for Arable Research, Christchurch, New Zealand.
Buddenhagen CE; AgResearch Ltd., Ruakura Research Centre, Hamilton, New Zealand.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2024 Mar 07; Vol. 19 (3), pp. e0299539. Date of Electronic Publication: 2024 Mar 07 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Herbicides*/pharmacology
Atrazine*
Pyridines*
Sulfonylurea Compounds*
Plant Weeds ; Zea mays ; Dicamba ; New Zealand ; Herbicide Resistance

Czasopismo naukowe

na półce

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Skocz do pozycji: 11.

Tytuł:: Toxoplasma sortilin interacts with secretory proteins and it is critical for parasite proliferation.
Autorzy:: Li C; Key Laboratory of Livestock Infectious Diseases, Ministry of Education, and Key Laboratory of Ruminant Infectious Disease Prevention and Control (East), Ministry of Agriculture and Rural Affairs, College of Animal Science and Veterinary Medicine, Shenyang Agricultural University, 120 Dongling Road, Shenyang, 110866, China.; Research Unit for Pathogenic Mechanisms of Zoonotic Parasites, Chinese Academy of Medical Sciences, 120 Dongling Road, Shenyang, 110866, China.
Jiang N; Key Laboratory of Livestock Infectious Diseases, Ministry of Education, and Key Laboratory of Ruminant Infectious Disease Prevention and Control (East), Ministry of Agriculture and Rural Affairs, College of Animal Science and Veterinary Medicine, Shenyang Agricultural University, 120 Dongling Road, Shenyang, 110866, China.; Research Unit for Pathogenic Mechanisms of Zoonotic Parasites, Chinese Academy of Medical Sciences, 120 Dongling Road, Shenyang, 110866, China.
Liu Y; Key Laboratory of Livestock Infectious Diseases, Ministry of Education, and Key Laboratory of Ruminant Infectious Disease Prevention and Control (East), Ministry of Agriculture and Rural Affairs, College of Animal Science and Veterinary Medicine, Shenyang Agricultural University, 120 Dongling Road, Shenyang, 110866, China.; Research Unit for Pathogenic Mechanisms of Zoonotic Parasites, Chinese Academy of Medical Sciences, 120 Dongling Road, Shenyang, 110866, China.
Zhang Y; Key Laboratory of Livestock Infectious Diseases, Ministry of Education, and Key Laboratory of Ruminant Infectious Disease Prevention and Control (East), Ministry of Agriculture and Rural Affairs, College of Animal Science and Veterinary Medicine, Shenyang Agricultural University, 120 Dongling Road, Shenyang, 110866, China.; Research Unit for Pathogenic Mechanisms of Zoonotic Parasites, Chinese Academy of Medical Sciences, 120 Dongling Road, Shenyang, 110866, China.
Chen R; Key Laboratory of Livestock Infectious Diseases, Ministry of Education, and Key Laboratory of Ruminant Infectious Disease Prevention and Control (East), Ministry of Agriculture and Rural Affairs, College of Animal Science and Veterinary Medicine, Shenyang Agricultural University, 120 Dongling Road, Shenyang, 110866, China.; Research Unit for Pathogenic Mechanisms of Zoonotic Parasites, Chinese Academy of Medical Sciences, 120 Dongling Road, Shenyang, 110866, China.
Feng Y; Key Laboratory of Livestock Infectious Diseases, Ministry of Education, and Key Laboratory of Ruminant Infectious Disease Prevention and Control (East), Ministry of Agriculture and Rural Affairs, College of Animal Science and Veterinary Medicine, Shenyang Agricultural University, 120 Dongling Road, Shenyang, 110866, China.; Research Unit for Pathogenic Mechanisms of Zoonotic Parasites, Chinese Academy of Medical Sciences, 120 Dongling Road, Shenyang, 110866, China.
Sang X; Key Laboratory of Livestock Infectious Diseases, Ministry of Education, and Key Laboratory of Ruminant Infectious Disease Prevention and Control (East), Ministry of Agriculture and Rural Affairs, College of Animal Science and Veterinary Medicine, Shenyang Agricultural University, 120 Dongling Road, Shenyang, 110866, China.; Research Unit for Pathogenic Mechanisms of Zoonotic Parasites, Chinese Academy of Medical Sciences, 120 Dongling Road, Shenyang, 110866, China.
Chen Q; Key Laboratory of Livestock Infectious Diseases, Ministry of Education, and Key Laboratory of Ruminant Infectious Disease Prevention and Control (East), Ministry of Agriculture and Rural Affairs, College of Animal Science and Veterinary Medicine, Shenyang Agricultural University, 120 Dongling Road, Shenyang, 110866, China. .; Research Unit for Pathogenic Mechanisms of Zoonotic Parasites, Chinese Academy of Medical Sciences, 120 Dongling Road, Shenyang, 110866, China. .; Pokaż więcej
Źródło:: Parasites & vectors [Parasit Vectors] 2024 Mar 04; Vol. 17 (1), pp. 105. Date of Electronic Publication: 2024 Mar 04.
Typ publikacji:: Journal Article
MeSH Terms:: Toxoplasma*/genetics
Parasites*
Hydrocarbons, Fluorinated*
Pyridines*
Adaptor Proteins, Vesicular Transport*
Humans ; Animals ; Mice ; Cell Proliferation

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Skocz do pozycji: 12.

Tytuł:: Impact of preexisting proteinuria on the development of regorafenib-induced problematic proteinuria in real-world metastatic colorectal cancer treatment.
Autorzy:: Saito Y; Department of Clinical Pharmaceutics & Therapeutics, Faculty of Pharmaceutical Sciences, Hokkaido University of Science, 4-1, Maeda 7-Jo 15-Chome, Teine-Ku, Sapporo, Hokkaido, 006-8585, Japan. .
Takekuma Y; Department of Pharmacy, Hokkaido University Hospital, Kita 14-Jo, Nishi 5-Chome, Kita-Ku, Sapporo, 060-8648, Japan.
Komatsu Y; Cancer Center, Hokkaido University Hospital, Kita 14-Jo, Nishi 5-Chome, Kita-Ku, Sapporo, 060-8648, Japan.
Sugawara M; Department of Pharmacy, Hokkaido University Hospital, Kita 14-Jo, Nishi 5-Chome, Kita-Ku, Sapporo, 060-8648, Japan.; Laboratory of Pharmacokinetics, Faculty of Pharmaceutical Sciences, Hokkaido University, Kita 12-Jo, Nishi 6-Chome, Kita-Ku, Sapporo, 060-0812, Japan.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Mar 02; Vol. 14 (1), pp. 5153. Date of Electronic Publication: 2024 Mar 02.
Typ publikacji:: Journal Article
MeSH Terms:: Colorectal Neoplasms*/pathology
Colonic Neoplasms*/chemically induced
Rectal Neoplasms*
Pyridines*
Humans ; Vascular Endothelial Growth Factor A ; Retrospective Studies ; Phenylurea Compounds/adverse effects

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Skocz do pozycji: 13.

Tytuł:: The oral IRAK4 inhibitors zabedosertib and BAY1830839 suppress local and systemic immune responses in a randomized trial in healthy male volunteers.
Autorzy:: Jodl SJ; Bayer AG, Berlin, Germany.
Ten Voorde W; Centre for Human Drug Research, Leiden, The Netherlands.; Leiden University Medical Center, Leiden, The Netherlands.
Klein S; Bayer AG, Berlin, Germany.
Wagenfeld A; Bayer AG, Berlin, Germany.
Zollmann FS; Pharma Consult, Berlin, Germany.
Feldmüller M; Bayer AG, Berlin, Germany.
Klarenbeek NB; Centre for Human Drug Research, Leiden, The Netherlands.
de Bruin DT; Centre for Human Drug Research, Leiden, The Netherlands.
Jansen MAA; Centre for Human Drug Research, Leiden, The Netherlands.
Rissmann R; Centre for Human Drug Research, Leiden, The Netherlands.; Leiden Academic Centre for Drug Research, Leiden, The Netherlands.
Rohde B; Bayer AG, Berlin, Germany.
Moerland M; Centre for Human Drug Research, Leiden, The Netherlands.; Leiden University Medical Center, Leiden, The Netherlands.; Pokaż więcej
Źródło:: Clinical and translational science [Clin Transl Sci] 2024 Mar; Vol. 17 (3), pp. e13771.
Typ publikacji:: Randomized Controlled Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Interleukin-1 Receptor-Associated Kinases*
Lipopolysaccharides*
Indazoles*
Pyridines*
Humans ; Male ; Erythema ; Prednisolone ; Imiquimod ; Immunity ; Volunteers

Czasopismo naukowe

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Skocz do pozycji: 14.

Tytuł:: Evaluation of outcomes of calcitonin gene-related peptide (CGRP)-targeting therapies for acute and preventive migraine treatment based on patient sex.
Autorzy:: Porreca F; Department of Pharmacology, University of Arizona, Tucson, USA.; Mayo Clinic Arizona, Phoenix, USA.
Navratilova E; Department of Pharmacology, University of Arizona, Tucson, USA.; Mayo Clinic Arizona, Phoenix, USA.
Hirman J; Pacific Northwest Statistical Consulting, Woodinville, USA.
van den Brink AM; Department of Internal Medicine, Division of Pharmacology, Vascular Medicine and Metabolic Diseases, Erasmus MC University Medical Center Rotterdam, The Netherlands.
Lipton RB; Departments of Neurology, Psychiatry and Behavioral Science, and Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA.
Dodick DW; Mayo Clinic Arizona, Phoenix, USA.; Atria Academy of Science and Medicine, New York, USA.; Pokaż więcej
Źródło:: Cephalalgia : an international journal of headache [Cephalalgia] 2024 Mar; Vol. 44 (3), pp. 3331024241238153.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Calcitonin Gene-Related Peptide*
Migraine Disorders*/drug therapy
Piperidines*
Pyridines*
Pyrroles*
Spiro Compounds*
Female ; Humans ; Male ; Calcitonin Gene-Related Peptide Receptor Antagonists/therapeutic use ; Antibodies, Monoclonal/therapeutic use ; Pain/drug therapy

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Skocz do pozycji: 15.

Tytuł:: No clinically relevant electrocardiogram effects in a randomized TQT study of single therapeutic/supratherapeutic rimegepant doses in healthy adults.
Autorzy:: Bhardwaj R; Certara USA, Princeton, New Jersey, USA.
Hanna MS; Biohaven Pharmaceuticals Inc., New Haven, Connecticut, USA.
Morris BA; Biohaven Pharmaceuticals Inc., New Haven, Connecticut, USA.
Matschke KT; Pfizer Inc., New York, New York, USA.
Bertz R; Biohaven Pharmaceuticals Inc., New Haven, Connecticut, USA.
Croop RS; Biohaven Pharmaceuticals Inc., New Haven, Connecticut, USA.
Liu J; Pfizer Inc., New York, New York, USA.; Pokaż więcej
Źródło:: Clinical and translational science [Clin Transl Sci] 2024 Mar; Vol. 17 (3), pp. e13727.
Typ publikacji:: Randomized Controlled Trial; Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Piperidines*
Electrocardiography*
Pyridines*
Adult ; Humans ; Cross-Over Studies ; Moxifloxacin

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Skocz do pozycji: 16.

Tytuł:: Economic and budgetary impact evaluation of isavuconazole (Cresemba®) versus voriconazole (Vfend®) for the treatment of patients with possible invasive aspergillosis from the perspective of the Brazilian supplementary health system.
Autorzy:: Araujo GLV; Knight Therapeutics, São Paulo, Brazil.
Murta Amaral L; ORIGIN Health, São Paulo, Brazil.
Ponzio V; Federal University of São Paulo, UNIFESP, São Paulo, Brazil.
Rocha JL; Faculty of Medicine of the Pontifical Catholic University of Paraná, PUC, Paraná, Brazil.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2024 Mar 01; Vol. 19 (3), pp. e0299056. Date of Electronic Publication: 2024 Mar 01 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Aspergillosis*/drug therapy
Invasive Fungal Infections*/drug therapy
Nitriles*
Pyridines*
Humans ; Voriconazole/therapeutic use ; Brazil ; Triazoles/therapeutic use

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Skocz do pozycji: 17.

Tytuł:: Geographic Variation and Environmental Predictors of Nontuberculous Mycobacteria in Laboratory Surveillance, Virginia, USA, 2021-2023 .
Autorzy:: Mullen B
Houpt ER
Colston J
Becker L
Johnson S
Young L
Hearn J
Falkinham J 3rd
Heysell SK; Pokaż więcej
Źródło:: Emerging infectious diseases [Emerg Infect Dis] 2024 Mar; Vol. 30 (3), pp. 548-554.
Typ publikacji:: Journal Article
MeSH Terms:: Nontuberculous Mycobacteria*
Mycobacterium abscessus*
Carbamates*
Pyrazines*
Pyridines*
Virginia/epidemiology ; Mycobacterium avium Complex ; Water

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Skocz do pozycji: 18.

Tytuł:: Activation of AMPK pathway by low‑dose donafenib and atorvastatin combination improves high‑fat diet‑induced metabolic dysfunction‑associated steatotic liver disease.
Autorzy:: Bai Y; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, P.R. China.
Chen K; Department of Gastroenterology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510120, P.R. China.
Liu J; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, P.R. China.
Wang Y; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, P.R. China.
Wang C; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, P.R. China.
Ju S; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, P.R. China.
Zhou C; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, P.R. China.
Yao W; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, P.R. China.
Xiong B; Department of Interventional Radiology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510120, P.R. China.
Zheng C; Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, P.R. China.; Pokaż więcej
Źródło:: Molecular medicine reports [Mol Med Rep] 2024 Mar; Vol. 29 (3). Date of Electronic Publication: 2024 Feb 01.
Typ publikacji:: Journal Article
MeSH Terms:: Non-alcoholic Fatty Liver Disease*/etiology
Non-alcoholic Fatty Liver Disease*/complications
Metabolic Diseases*/complications
Pyridines*
Rats ; Animals ; Humans ; AMP-Activated Protein Kinases/metabolism ; Atorvastatin/pharmacology ; Atorvastatin/therapeutic use ; Reactive Oxygen Species/metabolism ; Diet, High-Fat/adverse effects ; Liver/metabolism ; Lipid Metabolism ; Hep G2 Cells

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Skocz do pozycji: 19.

Tytuł:: Mortality after major bleeding in Asian atrial fibrillation patients receiving different direct oral anticoagulants: a nationwide, propensity score study.
Autorzy:: Yu JH; Department of Emergency Medicine, China Medical University Hsinchu Hospital, China Medical University, Hsinchu, Taiwan.; Graduate Institute of Management, Chang Gung University, Taoyuan City, Taiwan.
Li PR; Department of Public Health, College of Medicine, Chang Gung University, 259, Wenhua 1st Rd., Guishan Dist., Taoyuan City, 33302, Taiwan.
Chen DY; Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital at Linkou, Taoyuan City, Taiwan.; School of Medicine, College of Medicine, Chang Gung University, Taoyuan City, Taiwan.
Huang WK; School of Medicine, College of Medicine, Chang Gung University, Taoyuan City, Taiwan.; Division of Hematology/Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital at Linkou, Taoyuan City, Taiwan.
See LC; Department of Public Health, College of Medicine, Chang Gung University, 259, Wenhua 1st Rd., Guishan Dist., Taoyuan City, 33302, Taiwan. .; Division of Rheumatology, Allergy, and Immunology, Chang Gung Memorial Hospital at Linkou, Taoyuan City, Taiwan. .; Biostatistics Core Laboratory, Molecular Medicine Research Center, Chang Gung University, Taoyuan City, Taiwan. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Feb 27; Vol. 14 (1), pp. 4771. Date of Electronic Publication: 2024 Feb 27.
Typ publikacji:: Journal Article
MeSH Terms:: Atrial Fibrillation*/complications
Atrial Fibrillation*/drug therapy
Stroke*/complications
Pyridines*
Thiazoles*
Humans ; Rivaroxaban ; Dabigatran/adverse effects ; Anticoagulants/adverse effects ; Warfarin ; Factor Xa Inhibitors/adverse effects ; Propensity Score ; Retrospective Studies ; Hemorrhage/drug therapy ; Administration, Oral

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Skocz do pozycji: 20.

Tytuł:: Dynamic contrast-enhanced magnetic resonance imaging assessment of residual tumor angiogenesis after insufficient microwave ablation and donafenib adjuvant therapy.
Autorzy:: Ren Z; Department of Radiology, Affiliated Hospital of North Sichuan Medical College, 1 Maoyuan Road, Nanchong City, 637000, Sichuan Province, China.
Feng G; Department of Radiology, Affiliated Hospital of North Sichuan Medical College, 1 Maoyuan Road, Nanchong City, 637000, Sichuan Province, China.
Li B; Department of Radiology, Affiliated Hospital of North Sichuan Medical College, 1 Maoyuan Road, Nanchong City, 637000, Sichuan Province, China.
Zhang C; Department of Radiology, Affiliated Hospital of North Sichuan Medical College, 1 Maoyuan Road, Nanchong City, 637000, Sichuan Province, China.
Du Y; Department of Radiology, Affiliated Hospital of North Sichuan Medical College, 1 Maoyuan Road, Nanchong City, 637000, Sichuan Province, China. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Feb 24; Vol. 14 (1), pp. 4557. Date of Electronic Publication: 2024 Feb 24.
Typ publikacji:: Journal Article
MeSH Terms:: Vascular Endothelial Growth Factor A*
Liver Neoplasms*/diagnostic imaging
Liver Neoplasms*/drug therapy
Pyridines*
Animals ; Rabbits ; Neoplasm, Residual/diagnostic imaging ; Microwaves ; Angiogenesis ; Magnetic Resonance Imaging/methods ; Neovascularization, Pathologic/diagnostic imaging ; Neovascularization, Pathologic/pathology ; Contrast Media

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