Temat: "Pyrrolizidine Alkaloids" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Pyrrolizidine Alkaloids in Foods, Herbal Drugs, and Food Supplements: Chemistry, Metabolism, Toxicological Significance, Analytical Methods, Occurrence, and Challenges for Future.
Autorzy:: Tábuas B; Faculty of Pharmacy, University of Coimbra, Polo III, Azinhaga de Santa Comba, 3000-548 Coimbra, Portugal.
Cruz Barros S; National Institute for Agricultural and Veterinary Research (INIAV), I.P, 4485-655 Vila do Conde, Portugal.
Diogo C; Faculty of Pharmacy, University of Coimbra, Polo III, Azinhaga de Santa Comba, 3000-548 Coimbra, Portugal.
Cavaleiro C; Faculty of Pharmacy, University of Coimbra, Polo III, Azinhaga de Santa Comba, 3000-548 Coimbra, Portugal.; Chemical Process Engineering and Forest Products Research Centre (CIEPQPF), University of Coimbra, Rua Sílvio Lima, 3030-790 Coimbra, Portugal.
Sanches Silva A; Faculty of Pharmacy, University of Coimbra, Polo III, Azinhaga de Santa Comba, 3000-548 Coimbra, Portugal.; Center for Study in Animal Science (CECA), Institute of Sciences, Technologies and Agro-Environment of the University of Porto (ICETA), University of Porto, 4501-401 Porto, Portugal.; Associate Laboratory for Animal and Veterinary Sciences (AL4AnimalS), 1300-477 Lisbon, Portugal.; Pokaż więcej
Źródło:: Toxins [Toxins (Basel)] 2024 Feb 02; Vol. 16 (2). Date of Electronic Publication: 2024 Feb 02.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Pyrrolizidine Alkaloids*/toxicity
Pyrrolizidine Alkaloids*/chemistry
Plants/chemistry ; Dietary Supplements/toxicity ; Dietary Supplements/analysis ; Carcinogens

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Skocz do pozycji: 2.

Tytuł:: Pyrrolizidine Alkaloids-Pros and Cons for Pharmaceutical and Medical Applications.
Autorzy:: Jayawickreme K; Student Scientific Club of Phytochemists, Institute of Biological Sciences, Faculty of Biology and Biotechnology, Maria Curie-Skłodowska University, Akademicka St. 19, 20-033 Lublin, Poland.
Świstak D; Student Scientific Club of Phytochemists, Institute of Biological Sciences, Faculty of Biology and Biotechnology, Maria Curie-Skłodowska University, Akademicka St. 19, 20-033 Lublin, Poland.
Ozimek E; Department of Industrial and Environmental Microbiology, Institute of Biological Sciences, Faculty of Biology and Biotechnology, Maria Curie-Skłodowska University, Akademicka St. 19, 20-033 Lublin, Poland.
Reszczyńska E; Department of Biochemistry and Molecular Biology, Medical University of Lublin, Chodźki St. 1, 20-093 Lublin, Poland.; Department of Plant Physiology and Biophysics, Institute of Biological Sciences, Faculty of Biology and Biotechnology, Maria Curie-Skłodowska University, Akademicka St. 19, 20-033 Lublin, Poland.
Rysiak A; Department of Botany, Mycology, and Ecology, Institute of Biological Sciences, Faculty of Biology and Biotechnology, Maria Curie-Skłodowska University, Akademicka St. 19, 20-033 Lublin, Poland.
Makuch-Kocka A; Department of Pharmacology, Medical University of Lublin, Radziwiłłowska St. 11, 20-080 Lublin, Poland.
Hanaka A; Department of Plant Physiology and Biophysics, Institute of Biological Sciences, Faculty of Biology and Biotechnology, Maria Curie-Skłodowska University, Akademicka St. 19, 20-033 Lublin, Poland.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Nov 30; Vol. 24 (23). Date of Electronic Publication: 2023 Nov 30.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Pyrrolizidine Alkaloids*/therapeutic use
Pyrrolizidine Alkaloids*/toxicity
Humans ; Pharmaceutical Preparations ; Plants/metabolism

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Skocz do pozycji: 3.

Tytuł:: Analysis of Pyrrolizidine Alkaloids in Stingless Bee Honey and Identification of a Botanical Source as Ageratum conyzoides .
Autorzy:: Hungerford NL; Queensland Alliance for Agriculture and Food Innovation (QAAFI), The University of Queensland, Health and Food Sciences Precinct, Coopers Plains, QLD 4108, Australia.
Zawawi N; Queensland Alliance for Agriculture and Food Innovation (QAAFI), The University of Queensland, Health and Food Sciences Precinct, Coopers Plains, QLD 4108, Australia.; Faculty of Food Science and Technology, University Putra Malaysia, Serdang 43400, Malaysia.
Zhu TE; Queensland Alliance for Agriculture and Food Innovation (QAAFI), The University of Queensland, Health and Food Sciences Precinct, Coopers Plains, QLD 4108, Australia.
Carter SJ; Forensic and Scientific Services, Queensland Health, Coopers Plains, QLD 4108, Australia.
Melksham KJ; Forensic and Scientific Services, Queensland Health, Coopers Plains, QLD 4108, Australia.
Fletcher MT; Queensland Alliance for Agriculture and Food Innovation (QAAFI), The University of Queensland, Health and Food Sciences Precinct, Coopers Plains, QLD 4108, Australia.; Pokaż więcej
Źródło:: Toxins [Toxins (Basel)] 2024 Jan 12; Vol. 16 (1). Date of Electronic Publication: 2024 Jan 12.
Typ publikacji:: Journal Article
MeSH Terms:: Honey*
Ageratum*
Pyrrolizidine Alkaloids*/toxicity
Marijuana Abuse*
Bees ; Animals ; Tandem Mass Spectrometry ; Australia ; Oxides

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Skocz do pozycji: 4.

Tytuł:: Metabolite Profiling in the Liver, Plasma and Milk of Dairy Cows Exposed to Tansy Ragwort ( Senecio jacobae ) Pyrrolizidine Alkaloids.
Autorzy:: Huber K; Institute of Animal Science, University of Hohenheim, 70599 Stuttgart, Germany.
Saltzmann J; Institute of Animal Nutrition, Friedrich-Loeffler-Institute, 38116 Braunschweig, Germany.
Daenicke S; Institute of Animal Nutrition, Friedrich-Loeffler-Institute, 38116 Braunschweig, Germany.; Pokaż więcej
Źródło:: Toxins [Toxins (Basel)] 2023 Oct 06; Vol. 15 (10). Date of Electronic Publication: 2023 Oct 06.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Senecio*/chemistry
Pyrrolizidine Alkaloids*/toxicity
Pyrrolizidine Alkaloids*/analysis
Tanacetum*
Animals ; Female ; Cattle ; Milk/chemistry ; Plants, Toxic ; Liver ; Amino Acids/analysis

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Skocz do pozycji: 5.

Tytuł:: LC-MS/MS Evaluation of Pyrrolizidine Alkaloids Profile in Relation to Safety of Comfrey Roots and Leaves from Polish Sources.
Autorzy:: Kimel K; Department of Pharmacognosy with Medicinal Plants Garden, Faculty of Pharmacy, Medical University of Gdańsk, 107 Hallera St., 80-416 Gdansk, Poland.
Godlewska S; Department of Pharmacognosy with Medicinal Plants Garden, Faculty of Pharmacy, Medical University of Gdańsk, 107 Hallera St., 80-416 Gdansk, Poland.
Gleńsk M; Department of Pharmacognosy and Herbal Medicines, Wroclaw Medical University, 211A Borowska St., 50-556 Wrocław, Poland.
Gobis K; Department of Organic Chemistry, Faculty of Pharmacy, Medical University of Gdańsk, 107 Hallera St., 80-416 Gdansk, Poland.
Ośko J; Department of Bromatology, Faculty of Pharmacy, Medical University of Gdańsk, 107 Hallera St., 80-416 Gdansk, Poland.
Grembecka M; Department of Bromatology, Faculty of Pharmacy, Medical University of Gdańsk, 107 Hallera St., 80-416 Gdansk, Poland.
Krauze-Baranowska M; Department of Pharmacognosy with Medicinal Plants Garden, Faculty of Pharmacy, Medical University of Gdańsk, 107 Hallera St., 80-416 Gdansk, Poland.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Aug 21; Vol. 28 (16). Date of Electronic Publication: 2023 Aug 21.
Typ publikacji:: Journal Article
MeSH Terms:: Comfrey*
Boraginaceae*
Pyrrolizidine Alkaloids*
Chromatography, Liquid ; Tandem Mass Spectrometry ; Poland ; Plant Leaves

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Skocz do pozycji: 6.

Tytuł:: Pyrrolizidine Alkaloids in Food on the Italian Market.
Autorzy:: Peloso M; National Reference Laboratory for Plant Toxins in Food, Food Chemical Department, Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna, Via Fiorini 5, 40127 Bologna, Italy.
Minkoumba Sonfack G; National Reference Laboratory for Plant Toxins in Food, Food Chemical Department, Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna, Via Fiorini 5, 40127 Bologna, Italy.
Paduano S; Ministry of Health, General Directorate for Hygiene and Food Safety and Nutrition, Via G. Ribotta, 5, 00144 Rome, Italy.
De Martino M; Ministry of Health, General Directorate for Hygiene and Food Safety and Nutrition, Via G. Ribotta, 5, 00144 Rome, Italy.
De Santis B; National Reference Laboratory for Plant Toxins in Food, Food Chemical Department, Istituto Superiore di Sanità, Viale Regina Elena, 299, 00161 Rome, Italy.
Caprai E; National Reference Laboratory for Plant Toxins in Food, Food Chemical Department, Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna, Via Fiorini 5, 40127 Bologna, Italy.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Jul 11; Vol. 28 (14). Date of Electronic Publication: 2023 Jul 11.
Typ publikacji:: Journal Article
MeSH Terms:: Pyrrolizidine Alkaloids*/analysis
Honey*/analysis
Pregnancy ; Animals ; Child ; Female ; Humans ; Chromatography, Liquid ; Tandem Mass Spectrometry ; Plants/metabolism ; Tea ; Food Contamination/analysis

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Skocz do pozycji: 7.

Tytuł:: Risk assessment of short-term intake of pyrrolizidine alkaloids in food: derivation of an acute reference dose.
Autorzy:: Eckert E; Department of Risk Assessment, Bavarian Health and Food Safety Authority, Erlangen, Germany.; Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
Lepper H; Department of Risk Assessment, Bavarian Health and Food Safety Authority, Erlangen, Germany.
Hintzsche H; Department of Risk Assessment, Bavarian Health and Food Safety Authority, Erlangen, Germany.; Department of Food Safety, Institute of Food and Nutritional Sciences, University of Bonn, Bonn, Germany.; Pokaż więcej
Źródło:: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment [Food Addit Contam Part A Chem Anal Control Expo Risk Assess] 2023 Apr; Vol. 40 (4), pp. 588-596. Date of Electronic Publication: 2023 Feb 15.
Typ publikacji:: Journal Article
MeSH Terms:: Pyrrolizidine Alkaloids*/analysis
Animals ; Humans ; Rats ; Risk Assessment ; Carcinogens/toxicity ; Dietary Supplements/analysis ; Food Contamination/analysis

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Skocz do pozycji: 8.

Tytuł:: Enoxaparin attenuates pyrrolizidine alkaloids-induced hepatic sinusoidal obstruction syndrome by inhibiting oncostatin M expression.
Autorzy:: Xiang H; Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Liu C; Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Xiao Z; Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Du L; Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wei N; Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Liu F; Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Song Y; Department of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Pokaż więcej
Źródło:: Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2023 Mar; Vol. 43 (3), pp. 626-638. Date of Electronic Publication: 2022 Nov 28.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Hepatic Veno-Occlusive Disease*/chemically induced
Pyrrolizidine Alkaloids*/adverse effects
Rats ; Mice ; Animals ; Enoxaparin ; Retrospective Studies ; Heparin, Low-Molecular-Weight ; Oncostatin M/adverse effects ; Monocrotaline/adverse effects ; Anticoagulants/adverse effects

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Skocz do pozycji: 9.

Tytuł:: Development and Validation of an UHPLC-MS/MS Method for the Determination of 32 Pyrrolizidine Alkaloids in Chinese Wild Honey.
Autorzy:: Wu H; GRA (Shanghai) Standard Technology Service Co., Ltd, Research and Development Department, Shanghai 201318, P.R. China.
Fan D; GRA (Shanghai) Standard Technology Service Co., Ltd, Research and Development Department, Shanghai 201318, P.R. China.
Cheng J; GRA (Shanghai) Standard Technology Service Co., Ltd, Research and Development Department, Shanghai 201318, P.R. China.; Pokaż więcej
Źródło:: Journal of AOAC International [J AOAC Int] 2022 Dec 22; Vol. 106 (1), pp. 56-64.
Typ publikacji:: Journal Article
MeSH Terms:: Honey*/analysis
Pyrrolizidine Alkaloids*/analysis
Pyrrolizidine Alkaloids*/chemistry
Chromatography, High Pressure Liquid/methods ; Food Contamination/analysis ; Tandem Mass Spectrometry/methods

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Skocz do pozycji: 10.

Tytuł:: A sensitive LC-MS/MS method for isomer separation and quantitative determination of 51 pyrrolizidine alkaloids and two tropane alkaloids in cow's milk.
Autorzy:: Klein LM; Chair of Food Safety and Analytics, Faculty of Veterinary Medicine, Ludwig Maximilian University of Munich, Schoenleutnerstr. 8, 85764, Oberschleissheim, Germany. .; Chair of Analytical Food Chemistry, TUM School of Life Sciences Weihenstephan, Technical University of Munich, Maximus-von-Imhof-Forum 2, 85354, Freising, Germany. .
Gabler AM; Chair of Food Safety and Analytics, Faculty of Veterinary Medicine, Ludwig Maximilian University of Munich, Schoenleutnerstr. 8, 85764, Oberschleissheim, Germany.
Rychlik M; Chair of Analytical Food Chemistry, TUM School of Life Sciences Weihenstephan, Technical University of Munich, Maximus-von-Imhof-Forum 2, 85354, Freising, Germany.
Gottschalk C; Chair of Food Safety and Analytics, Faculty of Veterinary Medicine, Ludwig Maximilian University of Munich, Schoenleutnerstr. 8, 85764, Oberschleissheim, Germany.; Unit Plant Toxins and Mycotoxins, Department Safety in the Food Chain, German Federal Institute for Risk Assessment, Max-Dohrn-Str. 8-10, 10589, Berlin, Germany.
Kaltner F; Chair of Food Safety and Analytics, Faculty of Veterinary Medicine, Ludwig Maximilian University of Munich, Schoenleutnerstr. 8, 85764, Oberschleissheim, Germany.; Institute of Food Chemistry and Food Biotechnology, Justus Liebig University of Giessen, Heinrich-Buff-Ring 17-19, 35392, Giessen, Germany.; Pokaż więcej
Źródło:: Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2022 Nov; Vol. 414 (28), pp. 8107-8124. Date of Electronic Publication: 2022 Oct 01.
Typ publikacji:: Journal Article
MeSH Terms:: Pyrrolizidine Alkaloids*/analysis
Animals ; Chromatography, Liquid/methods ; Milk/chemistry ; Tandem Mass Spectrometry/methods ; Tropanes/analysis ; Chromatography, High Pressure Liquid

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Skocz do pozycji: 11.

Tytuł:: Combined Hepatotoxicity and Toxicity Mechanism of Intermedine and Lycopsamine.
Autorzy:: Wang Z; Tea Research Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310008, China.; College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310008, China.
Qiao L; The First Affiliated Hospital, College of Clinical Medicine of Henan University of Science and Technology, Luoyang 471003, China.
Zheng Q; Tea Research Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310008, China.; Key Laboratory of Tea Quality and Safety & Risk Assessment, Ministry of Agriculture, Hangzhou 310008, China.
Han H; Tea Research Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310008, China.; Key Laboratory of Tea Quality and Safety & Risk Assessment, Ministry of Agriculture, Hangzhou 310008, China.
Li Z; College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310008, China.
Zhang X; Tea Research Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310008, China.; Key Laboratory of Tea Quality and Safety & Risk Assessment, Ministry of Agriculture, Hangzhou 310008, China.
Chen H; Tea Research Institute, Chinese Academy of Agricultural Sciences, Hangzhou 310008, China.; Key Laboratory of Tea Quality and Safety & Risk Assessment, Ministry of Agriculture, Hangzhou 310008, China.; Pokaż więcej
Źródło:: Toxins [Toxins (Basel)] 2022 Sep 13; Vol. 14 (9). Date of Electronic Publication: 2022 Sep 13.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Chemical and Drug Induced Liver Injury*/etiology
Pyrrolizidine Alkaloids*/analysis
Pyrrolizidine Alkaloids*/toxicity
Annexin A5 ; Apoptosis ; Endoplasmic Reticulum Stress ; Humans ; Reactive Oxygen Species ; Sincalide ; Tea

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Skocz do pozycji: 12.

Tytuł:: Effect of Adulteration on Quality and Preliminary Risk Assessment of the Decoction Pieces of Farfarae Flos Based on the Determination of Hepatotoxic Pyrrolizidine Alkaloids by UHPLC-MS/MS.
Autorzy:: Li AP; CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences (CAS), 18 Tianshui Middle Road, Lanzhou 730000, PR China.; Gansu Institute for Drug Control, Key Laboratory for Quality Control of Chinese Medicinal Materials and Decoction Pieces, National Medical Products Administration (NMPA), Lanzhou 730000, PR China.; University of Chinese Academy of Sciences, Beijing 100049, PR China.
Shi YP; CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences (CAS), 18 Tianshui Middle Road, Lanzhou 730000, PR China.; Pokaż więcej
Źródło:: Journal of AOAC International [J AOAC Int] 2022 Dec 22; Vol. 106 (1), pp. 192-204.
Typ publikacji:: Journal Article
MeSH Terms:: Pyrrolizidine Alkaloids*/analysis
Drugs, Chinese Herbal*/analysis
Chromatography, High Pressure Liquid/methods ; Tandem Mass Spectrometry ; Flowers/chemistry ; Risk Assessment

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Skocz do pozycji: 13.

Tytuł:: Defibrotide improved the outcome of monocrotaline induced rat hepatic sinusoidal obstruction syndrome.
Autorzy:: Liu Z; The Third Unit, Department of Hepatology, Beijing Youan Hospital, Capital Medical University, No. 8, Youwai Xitoutiao Street, Fengtai District, 100069, Beijing, China.
Liang S; The Third Unit, Department of Hepatology, Beijing Youan Hospital, Capital Medical University, No. 8, Youwai Xitoutiao Street, Fengtai District, 100069, Beijing, China.
Wei X; The Third Unit, Department of Hepatology, Beijing Youan Hospital, Capital Medical University, No. 8, Youwai Xitoutiao Street, Fengtai District, 100069, Beijing, China.
Du X; The Third Unit, Department of Hepatology, Beijing Youan Hospital, Capital Medical University, No. 8, Youwai Xitoutiao Street, Fengtai District, 100069, Beijing, China.
Zhang J; The Third Unit, Department of Hepatology, Beijing Youan Hospital, Capital Medical University, No. 8, Youwai Xitoutiao Street, Fengtai District, 100069, Beijing, China. .; Pokaż więcej
Źródło:: BMC gastroenterology [BMC Gastroenterol] 2022 Dec 16; Vol. 22 (1), pp. 525. Date of Electronic Publication: 2022 Dec 16.
Typ publikacji:: Journal Article
MeSH Terms:: Hepatic Veno-Occlusive Disease*/chemically induced
Hepatic Veno-Occlusive Disease*/drug therapy
Hepatic Veno-Occlusive Disease*/pathology
Pyrrolizidine Alkaloids*/adverse effects
Male ; Rats ; Animals ; Monocrotaline/adverse effects ; Rats, Sprague-Dawley ; Anticoagulants/therapeutic use

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Skocz do pozycji: 14.

Tytuł:: Comment on Pyrrolizidine Alkaloids and Terpenes from Senecio (Asteraceae): Chemistry and Research Gaps in Africa.
Autorzy:: Sadgrove NJ; Department of Botany and Plant Biotechnology, University of Johannesburg (Auckland Park Campus), P.O. Box 524, Auckland Park, Johannesburg 2006, South Africa.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2022 Dec 13; Vol. 27 (24). Date of Electronic Publication: 2022 Dec 13.
Typ publikacji:: Journal Article
MeSH Terms:: Pyrrolizidine Alkaloids*/chemistry
Senecio*/chemistry
Alkaloids*
Sesquiterpenes*
Animals ; Bees ; Terpenes ; Evidence Gaps ; Africa ; Polycyclic Sesquiterpenes

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Skocz do pozycji: 15.

Tytuł:: Structure-Dependent Toxicokinetics of Selected Pyrrolizidine Alkaloids In Vitro.
Autorzy:: Buchmueller J; German Federal Institute for Risk Assessment, Max-Dohrn-Str. 8-10, 10589 Berlin, Germany.
Kaltner F; Chair of Food Safety, Veterinary Faculty, Ludwig-Maximilians-Universität München, Schoenleutnerstr. 8, 85764 Oberschleissheim, Germany.; Institute of Food Chemistry and Food Biotechnology, Justus Liebig University of Giessen, 35392 Giessen, Germany.
Gottschalk C; German Federal Institute for Risk Assessment, Max-Dohrn-Str. 8-10, 10589 Berlin, Germany.; Chair of Food Safety, Veterinary Faculty, Ludwig-Maximilians-Universität München, Schoenleutnerstr. 8, 85764 Oberschleissheim, Germany.
Maares M; German Federal Institute for Risk Assessment, Max-Dohrn-Str. 8-10, 10589 Berlin, Germany.; Institute of Food Chemistry and Toxicology, Technische Universität Berlin, Straße des 17. Juni 135, 10623 Berlin, Germany.
Braeuning A; German Federal Institute for Risk Assessment, Max-Dohrn-Str. 8-10, 10589 Berlin, Germany.
Hessel-Pras S; German Federal Institute for Risk Assessment, Max-Dohrn-Str. 8-10, 10589 Berlin, Germany.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Aug 16; Vol. 23 (16). Date of Electronic Publication: 2022 Aug 16.
Typ publikacji:: Journal Article
MeSH Terms:: Pyrrolizidine Alkaloids*/chemistry
Animals ; Carcinogens/pharmacology ; Humans ; Liver/metabolism ; Microsomes, Liver/metabolism ; Toxicokinetics

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Skocz do pozycji: 16.

Tytuł:: Detection, dietary exposure assessment and risk evaluation of quinolones and pyrrolizidine alkaloids in commercial honey from Brazil.
Autorzy:: Bandini TB; Farmanguinhos - Departamento de Métodos Analíticos, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
Spisso BF; Laboratório de Resíduos de Medicamentos Veterinários Em Alimentos, Fundação Oswaldo Cruz - Instituto Nacional de Controle de Qualidade Em Saúde, Rio de Janeiro, Brazil.; Pokaż więcej
Źródło:: Food additives & contaminants. Part B, Surveillance [Food Addit Contam Part B Surveill] 2022 Jun; Vol. 15 (2), pp. 89-97. Date of Electronic Publication: 2022 Feb 03.
Typ publikacji:: Journal Article
MeSH Terms:: Honey*/analysis
Pyrrolizidine Alkaloids*/analysis
Pyrrolizidine Alkaloids*/toxicity
Quinolones*/toxicity
Brazil ; Dietary Exposure ; Food Contamination/analysis ; Humans

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Skocz do pozycji: 17.

Tytuł:: Correlation Investigation between Pyrrole-DNA and Pyrrole-Protein Adducts in Male ICR Mice Exposed to Retrorsine, a Hepatotoxic Pyrrolizidine Alkaloid.
Autorzy:: Zhu L; School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
Xue J; School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
He Y; School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.
Xia Q; National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, USA.
Fu PP; National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, USA.
Lin G; School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.; Pokaż więcej
Źródło:: Toxins [Toxins (Basel)] 2022 May 28; Vol. 14 (6). Date of Electronic Publication: 2022 May 28.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: DNA Adducts*/metabolism
DNA Adducts*/pharmacology
Pyrrolizidine Alkaloids*/toxicity
Animals ; Carcinogens/metabolism ; DNA/metabolism ; Liver ; Male ; Mice ; Mice, Inbred ICR ; Proteins/metabolism ; Pyrroles/toxicity

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Skocz do pozycji: 18.

Tytuł:: An Intramolecular Hydroaminomethylation-Based Approach to Pyrrolizidine Alkaloids under Microwave-Assisted Heating.
Autorzy:: Petricci E; Dipartimento di Biotecnologie, Chimica e Farmacia, Università degli Studi di Siena, Via A. Moro 2, 53100 Siena, Italy.
Zurzolo S; Dipartimento di Biotecnologie, Chimica e Farmacia, Università degli Studi di Siena, Via A. Moro 2, 53100 Siena, Italy.
Matassini C; Dipartimento di Chimica 'Ugo Schiff' (DICUS), Università degli Studi di Firenze, Via della Lastruccia 13, 50019 Sesto Fiorentino, Italy.
Maramai S; Dipartimento di Biotecnologie, Chimica e Farmacia, Università degli Studi di Siena, Via A. Moro 2, 53100 Siena, Italy.
Cardona F; Dipartimento di Chimica 'Ugo Schiff' (DICUS), Università degli Studi di Firenze, Via della Lastruccia 13, 50019 Sesto Fiorentino, Italy.
Goti A; Dipartimento di Chimica 'Ugo Schiff' (DICUS), Università degli Studi di Firenze, Via della Lastruccia 13, 50019 Sesto Fiorentino, Italy.
Taddei M; Dipartimento di Biotecnologie, Chimica e Farmacia, Università degli Studi di Siena, Via A. Moro 2, 53100 Siena, Italy.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2022 Jul 25; Vol. 27 (15). Date of Electronic Publication: 2022 Jul 25.
Typ publikacji:: Journal Article
MeSH Terms:: Alkaloids*/chemistry
Pyrrolizidine Alkaloids*/chemistry
Heating ; Ligands ; Microwaves

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Skocz do pozycji: 19.

Tytuł:: Effects of ensiling conditions on pyrrolizidine alkaloid degradation in silages mixed with two different Senecio spp.
Autorzy:: Klevenhusen F; Department Safety in the Food Chain, The German Federal Institute for Risk Assessment, Berlin, Germany.
These A; Department Safety in the Food Chain, The German Federal Institute for Risk Assessment, Berlin, Germany.
Taenzer J; Department Safety in the Food Chain, The German Federal Institute for Risk Assessment, Berlin, Germany.
Weiß K; of Agricultural and Horticultural Science, Humboldt-Universität zu BerlinAlbrecht Daniel Thaer-Institute, Berlin, Germany.
Pieper R; Department Safety in the Food Chain, The German Federal Institute for Risk Assessment, Berlin, Germany.; Pokaż więcej
Źródło:: Archives of animal nutrition [Arch Anim Nutr] 2022 Apr; Vol. 76 (2), pp. 93-111. Date of Electronic Publication: 2022 Jun 29.
Typ publikacji:: Journal Article
MeSH Terms:: Pyrrolizidine Alkaloids*/metabolism
Senecio*/chemistry
Animal Feed/analysis ; Animals ; Diet/veterinary ; Fermentation ; Humans ; Silage/analysis ; Soil ; Zea mays/chemistry

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Skocz do pozycji: 20.

Tytuł:: Isolation of Echimidine and Its C-7 Isomers from Echium plantagineum L. and Their Hepatotoxic Effect on Rat Hepatocytes.
Autorzy:: Gleńsk M; Department of Pharmacognosy and Herbal Drugs, Wroclaw Medical University, Borowska 211A, 50556 Wrocław, Poland.
Dudek MK; Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Sienkiewicza 112, 90363 Łódź, Poland.
Kinkade P; Planta Analytica LLC, 461 Danbury Rd., New Milford, CT 06776, USA.
Santos ECS; Centro de Inovação e Ensaios Pré-Clínicos (CIEnP), Av. Luiz Boiteux Piazza, 1302-Cachoeira do Bom Jesus, Florianópolis 88056000, SC, Brazil.
Glinski VB; Planta Analytica LLC, 461 Danbury Rd., New Milford, CT 06776, USA.
Ferreira D; Department of BioMolecular Sciences, Division of Pharmacognosy, Research Institute of Pharmaceutical Sciences, School of Pharmacy, University of Mississippi, Oxford, MI 38677, USA.
Seweryn E; Department of Chemistry and Immunochemistry, Wroclaw Medical University, M. Skłodowskiej-Curie 48/50, 50369 Wrocław, Poland.
Kaźmierski S; Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Sienkiewicza 112, 90363 Łódź, Poland.
Calixto JB; Centro de Inovação e Ensaios Pré-Clínicos (CIEnP), Av. Luiz Boiteux Piazza, 1302-Cachoeira do Bom Jesus, Florianópolis 88056000, SC, Brazil.
Glinski JA; Planta Analytica LLC, 461 Danbury Rd., New Milford, CT 06776, USA.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2022 Apr 30; Vol. 27 (9). Date of Electronic Publication: 2022 Apr 30.
Typ publikacji:: Journal Article
MeSH Terms:: Echium*/chemistry
Pyrrolizidine Alkaloids*/chemistry
Animals ; Hepatocytes/chemistry ; Rats ; Zinc

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