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    Wyświetlanie 1-19 z 19
    Tytuł:
    Tumor-derived small extracellular vesicles facilitate omental metastasis of ovarian cancer by triggering activation of mesenchymal stem cells.
    Autorzy:
    Gong L; Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
    Li G; Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
    Yi X; Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
    Han Q; Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.; Department of Obstetrics and Gynecology, The First College of Clinical Medical Science, China Three Gorges University, Yichang, Hubei, 443000, China.
    Wu Q; Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
    Ying F; Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
    Shen L; Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.; Department of Gynecology and Obstetrics, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, Jiangsu, China.
    Cao Y; Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.; Department of Obstetrics and Gynecology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
    Liu X; Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
    Gao L; Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
    Li W; Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
    Wang Z; Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. .
    Cai J; Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. .
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    Źródło:
    Cell communication and signaling : CCS [Cell Commun Signal] 2024 Jan 17; Vol. 22 (1), pp. 47. Date of Electronic Publication: 2024 Jan 17.
    Typ publikacji:
    Video-Audio Media; Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Ovarian Neoplasms*/pathology
    Extracellular Vesicles*/metabolism
    MicroRNAs*/genetics
    MicroRNAs*/metabolism
    Mesenchymal Stem Cells*/metabolism
    Humans ; Mice ; Animals ; Female ; Neoplasm Recurrence, Local ; Cell Proliferation ; Disease Models, Animal ; Integrins/metabolism ; Cell Line, Tumor ; Tumor Microenvironment
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Comprehensive transcriptomic analysis of three varieties with different brown planthopper-resistance identifies leaf sheath lncRNAs in rice.
    Autorzy:
    Liu K; Guangzhou Key Laboratory for Research and Development of Crop Germplasm Resources, Guangdong University Key Laboratory for Sustainable Control of Fruit and Vegetable Diseases and Pests & Key Laboratory of Green Prevention and Control on Fruits and Vegetables in South China, Ministry of Agriculture and Rural Affairs, Zhongkai University of Agriculture and Engineering, Guangzhou, 510225, China.
    Ma X; Guangdong Provincial Key Laboratory of New Technology in Rice Breeding, Rice Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou, 510642, China.
    Zhao L; Guangzhou Key Laboratory for Research and Development of Crop Germplasm Resources, Guangdong University Key Laboratory for Sustainable Control of Fruit and Vegetable Diseases and Pests & Key Laboratory of Green Prevention and Control on Fruits and Vegetables in South China, Ministry of Agriculture and Rural Affairs, Zhongkai University of Agriculture and Engineering, Guangzhou, 510225, China.
    Lai X; Guangzhou Key Laboratory for Research and Development of Crop Germplasm Resources, Guangdong University Key Laboratory for Sustainable Control of Fruit and Vegetable Diseases and Pests & Key Laboratory of Green Prevention and Control on Fruits and Vegetables in South China, Ministry of Agriculture and Rural Affairs, Zhongkai University of Agriculture and Engineering, Guangzhou, 510225, China.
    Chen J; Guangzhou Key Laboratory for Research and Development of Crop Germplasm Resources, Guangdong University Key Laboratory for Sustainable Control of Fruit and Vegetable Diseases and Pests & Key Laboratory of Green Prevention and Control on Fruits and Vegetables in South China, Ministry of Agriculture and Rural Affairs, Zhongkai University of Agriculture and Engineering, Guangzhou, 510225, China.
    Lang X; Guangzhou Key Laboratory for Research and Development of Crop Germplasm Resources, Guangdong University Key Laboratory for Sustainable Control of Fruit and Vegetable Diseases and Pests & Key Laboratory of Green Prevention and Control on Fruits and Vegetables in South China, Ministry of Agriculture and Rural Affairs, Zhongkai University of Agriculture and Engineering, Guangzhou, 510225, China.
    Han Q; Guangzhou Key Laboratory for Research and Development of Crop Germplasm Resources, Guangdong University Key Laboratory for Sustainable Control of Fruit and Vegetable Diseases and Pests & Key Laboratory of Green Prevention and Control on Fruits and Vegetables in South China, Ministry of Agriculture and Rural Affairs, Zhongkai University of Agriculture and Engineering, Guangzhou, 510225, China.
    Wan X; Guangzhou Key Laboratory for Research and Development of Crop Germplasm Resources, Guangdong University Key Laboratory for Sustainable Control of Fruit and Vegetable Diseases and Pests & Key Laboratory of Green Prevention and Control on Fruits and Vegetables in South China, Ministry of Agriculture and Rural Affairs, Zhongkai University of Agriculture and Engineering, Guangzhou, 510225, China. .
    Li C; Guangzhou Key Laboratory for Research and Development of Crop Germplasm Resources, Guangdong University Key Laboratory for Sustainable Control of Fruit and Vegetable Diseases and Pests & Key Laboratory of Green Prevention and Control on Fruits and Vegetables in South China, Ministry of Agriculture and Rural Affairs, Zhongkai University of Agriculture and Engineering, Guangzhou, 510225, China. .
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    Źródło:
    BMC plant biology [BMC Plant Biol] 2023 Jul 22; Vol. 23 (1), pp. 367. Date of Electronic Publication: 2023 Jul 22.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Hemiptera*
    MicroRNAs*/genetics
    Oryza*/genetics
    RNA, Long Noncoding*/genetics
    Plant Leaves/genetics ; Transcription Factors ; Transcriptome ; Animals
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Circ_0069094 regulates malignant phenotype and paclitaxel resistance in breast cancer cells via targeting the miR-136-5p/YWHAZ axis.
    Autorzy:
    Kong Z; Department of Ultrasound, Xianning Central Hospital, The First Affiliated Hospital of Hubei University of Science and Technology, Xianning City, China.
    Han Q; Department of Oncology, Xianning Central Hospital, The First Affiliated Hospital of Hubei University of Science and Technology, Xianning City, China.
    Zhu B; Department of Oncology, Xianning Central Hospital, The First Affiliated Hospital of Hubei University of Science and Technology, Xianning City, China.
    Wan L; Department of Ultrasound, Xianning Central Hospital, The First Affiliated Hospital of Hubei University of Science and Technology, Xianning City, China.
    Feng E; Department of Ultrasound, Xianning Hospital of Traditional Chinese Medicine, Xianning City, China.
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    Źródło:
    Thoracic cancer [Thorac Cancer] 2023 Jul; Vol. 14 (19), pp. 1831-1842. Date of Electronic Publication: 2023 May 16.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Breast Neoplasms*/drug therapy
    Breast Neoplasms*/genetics
    MicroRNAs*/genetics
    Humans ; Female ; Paclitaxel/pharmacology ; Breast ; Apoptosis ; Cell Count ; Cell Proliferation ; 14-3-3 Proteins
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    LncRNA NDRG1 aggravates osteosarcoma progression and regulates the PI3K/AKT pathway by sponging miR-96-5p.
    Autorzy:
    Wang Z; Department of Orthopaedics, Jinling Hospital, Nanjing Medical University, Zhongshan Road 305, Nanjing, 210002, China.
    Wei Y; Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Tianyuan East Road 818, Nanjing, 211166, China.
    Zhu H; Department of Orthopaedics, Affiliated Jianhu Hospital of Nantong University, Yancheng, China.
    Yu L; Department of Orthopaedics, Jinling Hospital, Nanjing University, Nanjing, China.
    Zhu J; Department of Orthopaedics, Jinling Hospital, Nanjing Medical University, Zhongshan Road 305, Nanjing, 210002, China.
    Han Q; Department of Orthopaedics, Jinling Hospital, Nanjing Medical University, Zhongshan Road 305, Nanjing, 210002, China.
    Liu Z; Department of Orthopaedics, Jinling Hospital, Nanjing University, Nanjing, China.
    Huang J; Department of Orthopaedics, Jinling Hospital, Southern Medical University, Nanjing, China.
    Zhu Y; Department of Orthopaedics, Jinling Hospital, Nanjing Medical University, Zhongshan Road 305, Nanjing, 210002, China.
    Fan G; Department of Orthopaedics, Jinling Hospital, Nanjing Medical University, Zhongshan Road 305, Nanjing, 210002, China.
    Tang Q; Department of Neurosurgery, Jiangsu Province Hospital and Nanjing Medical University First Affiliated Hospital, Nanjing, China.
    Qian J; Department of Digestion Medicine, Affiliated Yixing Hospital of Jiangsu University, Yixing, China.
    Chen X; Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Tianyuan East Road 818, Nanjing, 211166, China. .
    Zhou G; Department of Orthopaedics, Jinling Hospital, Nanjing Medical University, Zhongshan Road 305, Nanjing, 210002, China. .
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    Źródło:
    BMC cancer [BMC Cancer] 2022 Jul 04; Vol. 22 (1), pp. 728. Date of Electronic Publication: 2022 Jul 04.
    Typ publikacji:
    Journal Article; Retracted Publication
    MeSH Terms:
    Bone Neoplasms*/genetics
    MicroRNAs*/genetics
    Osteosarcoma*/genetics
    RNA, Long Noncoding*/genetics
    Animals ; Phosphatidylinositol 3-Kinases/genetics ; Proto-Oncogene Proteins c-akt
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Circ_0075804 Regulates the Expression of LASP1 by Targeting miR-1287-5p and Thus Affects the Biological Process of Retinoblastoma.
    Autorzy:
    Han Q; Department of Ophtalmology, Zaozhuang Municipal Hospital Shandong Province, Zaozhuang, Shandong, China.
    Ma L; Department of Ophtalmology, Zaozhuang Municipal Hospital Shandong Province, Zaozhuang, Shandong, China.
    Shao L; Department of Ophtalmology, Zaozhuang Municipal Hospital Shandong Province, Zaozhuang, Shandong, China.
    Wang H; Department of Ophtalmology, Zaozhuang Municipal Hospital Shandong Province, Zaozhuang, Shandong, China.
    Feng M; Department of Ophtalmology, Zaozhuang Municipal Hospital Shandong Province, Zaozhuang, Shandong, China.
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    Źródło:
    Current eye research [Curr Eye Res] 2022 Jul; Vol. 47 (7), pp. 1077-1086. Date of Electronic Publication: 2022 Apr 18.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Biological Phenomena*
    MicroRNAs*/genetics
    Retinal Neoplasms*/genetics
    Retinoblastoma*/genetics
    Adaptor Proteins, Signal Transducing/genetics ; Adaptor Proteins, Signal Transducing/metabolism ; Animals ; Cell Line, Tumor ; Cell Proliferation ; Cytoskeletal Proteins/genetics ; Cytoskeletal Proteins/metabolism ; Gene Expression Regulation, Neoplastic ; Humans ; LIM Domain Proteins/genetics ; LIM Domain Proteins/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    MiR-1290 promotes myoblast differentiation and protects against myotube atrophy via Akt/p70/FoxO3 pathway regulation.
    Autorzy:
    Che J; Department of Pain, Huadong Hospital, Shanghai Key Laboratory of Clinical Geriatric Medicine, Fudan University, No. 221, West YanAn Rd, Shanghai, 200040, P.R. China.
    Xu C; Department of Osteoporosis and Bone Disease, Huadong Hospital, Research Section of Geriatric Metabolic Bone Disease, Shanghai Geriatric Institute, Shanghai, China.
    Wu Y; Department of Pain, Huadong Hospital, Shanghai Key Laboratory of Clinical Geriatric Medicine, Fudan University, No. 221, West YanAn Rd, Shanghai, 200040, P.R. China.
    Jia P; Department of Pain, Huadong Hospital, Shanghai Key Laboratory of Clinical Geriatric Medicine, Fudan University, No. 221, West YanAn Rd, Shanghai, 200040, P.R. China.
    Han Q; Department of Pain, Huadong Hospital, Shanghai Key Laboratory of Clinical Geriatric Medicine, Fudan University, No. 221, West YanAn Rd, Shanghai, 200040, P.R. China.
    Ma Y; Department of Pain, Huadong Hospital, Shanghai Key Laboratory of Clinical Geriatric Medicine, Fudan University, No. 221, West YanAn Rd, Shanghai, 200040, P.R. China.
    Wang X; Department of Pain, Huadong Hospital, Shanghai Key Laboratory of Clinical Geriatric Medicine, Fudan University, No. 221, West YanAn Rd, Shanghai, 200040, P.R. China. .
    Zheng Y; Department of Pain, Huadong Hospital, Shanghai Key Laboratory of Clinical Geriatric Medicine, Fudan University, No. 221, West YanAn Rd, Shanghai, 200040, P.R. China. .
    Pokaż więcej
    Źródło:
    Skeletal muscle [Skelet Muscle] 2021 Mar 15; Vol. 11 (1), pp. 6. Date of Electronic Publication: 2021 Mar 15.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    MicroRNAs*/genetics
    Muscular Atrophy*/genetics
    Myoblasts/*cytology
    Animals ; Cell Differentiation ; Cell Line ; Forkhead Box Protein O3/genetics ; Humans ; Muscle Fibers, Skeletal ; Proto-Oncogene Proteins c-akt ; Rats
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Inhibition of miR-199a-5p rejuvenates aged mesenchymal stem cells derived from patients with idiopathic pulmonary fibrosis and improves their therapeutic efficacy in experimental pulmonary fibrosis.
    Autorzy:
    Shi L; The Second School of Clinical Medicine, Southern Medical University, Guangzhou, 510080, Guangdong, China.; Department of Emergency Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China.
    Han Q; Department of Respiratory Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Respiratory Health, State Key Laboratory of Respiratory Disease, Guangzhou, Guangdong, China.
    Hong Y; Department of Emergency Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China.
    Li W; Department of Emergency Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China.
    Gong G; Department of Respiratory Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Respiratory Health, State Key Laboratory of Respiratory Disease, Guangzhou, Guangdong, China.
    Cui J; Department of Emergency Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China.
    Mao M; Department of Respiratory Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Respiratory Health, State Key Laboratory of Respiratory Disease, Guangzhou, Guangdong, China.
    Liang X; Institute of Regenerative Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
    Hu B; Department of Emergency Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China.
    Li X; The Second School of Clinical Medicine, Southern Medical University, Guangzhou, 510080, Guangdong, China. .; Department of Emergency Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China. .
    Luo Q; Department of Respiratory Medicine, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Institute of Respiratory Health, State Key Laboratory of Respiratory Disease, Guangzhou, Guangdong, China. .
    Zhang Y; The Second School of Clinical Medicine, Southern Medical University, Guangzhou, 510080, Guangdong, China. .; Department of Emergency Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China. .
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    Źródło:
    Stem cell research & therapy [Stem Cell Res Ther] 2021 Feb 25; Vol. 12 (1), pp. 147. Date of Electronic Publication: 2021 Feb 25.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Idiopathic Pulmonary Fibrosis*/genetics
    Idiopathic Pulmonary Fibrosis*/therapy
    Mesenchymal Stem Cells*
    MicroRNAs*/genetics
    Aged ; Cellular Senescence ; Humans ; Sirtuin 1
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Long noncoding RNA LINC00514 accelerates pancreatic cancer progression by acting as a ceRNA of miR-28-5p to upregulate Rap1b expression.
    Autorzy:
    Han Q; Department of Oncology, the First Affiliated Hospital of Nanchang University, 17 Yongwaizheng Street, Nanchang, Jiangxi, 330006, People's Republic of China.
    Li J; Department of Oncology, the First Affiliated Hospital of Nanchang University, 17 Yongwaizheng Street, Nanchang, Jiangxi, 330006, People's Republic of China.
    Xiong J; Department of Oncology, the First Affiliated Hospital of Nanchang University, 17 Yongwaizheng Street, Nanchang, Jiangxi, 330006, People's Republic of China.
    Song Z; Department of Oncology, the First Affiliated Hospital of Nanchang University, 17 Yongwaizheng Street, Nanchang, Jiangxi, 330006, People's Republic of China. .
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    Źródło:
    Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2020 Aug 08; Vol. 39 (1), pp. 151. Date of Electronic Publication: 2020 Aug 08.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Gene Expression Regulation, Neoplastic*
    Biomarkers, Tumor/*metabolism
    MicroRNAs/*genetics
    Pancreatic Neoplasms/*pathology
    RNA, Long Noncoding/*genetics
    rap GTP-Binding Proteins/*metabolism
    Animals ; Apoptosis ; Biomarkers, Tumor/genetics ; Cell Movement ; Cell Proliferation ; Female ; Humans ; Male ; Mice ; Mice, Nude ; Middle Aged ; Pancreatic Neoplasms/genetics ; Pancreatic Neoplasms/metabolism ; Prognosis ; Survival Rate ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays ; rap GTP-Binding Proteins/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Lycium barbarum polysaccharide alleviates oxygen glucose deprivation-induced PC-12 cells damage by up-regulating miR-24.
    Autorzy:
    Song S; Department of Rehabilitation, Yantai Yuhuangding Hospital of Qingdao University Medical College , Yantai , China.
    Lin F; Department of Rehabilitation, Yantai Yuhuangding Hospital of Qingdao University Medical College , Yantai , China.
    Zhu P; Department of Acupuncture, Yantai Hospital of Traditional Chinese Medicine , Yantai , China.
    Wu C; Department of Acupuncture, Yantai Hospital of Traditional Chinese Medicine , Yantai , China.
    Zhao S; Department of Rehabilitation, Yantai Yuhuangding Hospital of Qingdao University Medical College , Yantai , China.
    Han Q; Department of Blood-Donation Service, Yantai Blood Center , Yantai , China.
    Li X; Department of Rehabilitation, Affiliated Hospital of Zunyi Medical College , Zunyi , China.
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    Źródło:
    Artificial cells, nanomedicine, and biotechnology [Artif Cells Nanomed Biotechnol] 2019 Dec; Vol. 47 (1), pp. 3994-4000.
    Typ publikacji:
    Journal Article; Retracted Publication
    MeSH Terms:
    Apoptosis/*drug effects
    Autophagy/*drug effects
    Drugs, Chinese Herbal/*pharmacology
    Glucose/*deficiency
    Hypoxia/*pathology
    MicroRNAs/*genetics
    Animals ; Cell Survival/drug effects ; Gene Expression/drug effects ; Gene Knockdown Techniques ; Hypoxia/genetics ; Hypoxia/metabolism ; MicroRNAs/metabolism ; PC12 Cells ; Phosphorylation/drug effects ; Rats ; Reactive Oxygen Species/metabolism ; Signal Transduction/drug effects
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    MiR-106b promotes therapeutic antibody expression in CHO cells by targeting deubiquitinase CYLD.
    Autorzy:
    Xu C; Institutes of Physical Science and Information Technology, Anhui University, Hefei, 230601, Anhui, People's Republic of China.
    Han Q; Institutes of Physical Science and Information Technology, Anhui University, Hefei, 230601, Anhui, People's Republic of China.
    Zhou Q; Institutes of Physical Science and Information Technology, Anhui University, Hefei, 230601, Anhui, People's Republic of China.
    Zhang L; Institutes of Physical Science and Information Technology, Anhui University, Hefei, 230601, Anhui, People's Republic of China.
    Wu P; Institutes of Physical Science and Information Technology, Anhui University, Hefei, 230601, Anhui, People's Republic of China.
    Lu Y; Institutes of Physical Science and Information Technology, Anhui University, Hefei, 230601, Anhui, People's Republic of China.
    Si Y; Institutes of Physical Science and Information Technology, Anhui University, Hefei, 230601, Anhui, People's Republic of China.
    Ma T; Biotechnical Research Centre for Anhui Tianxiang Cereals, Oils and Food stuffs Co., Ltd, Anhui University, Hefei, 230601, Anhui, People's Republic of China.
    Ma B; Biotechnical Research Centre for Anhui Tianxiang Cereals, Oils and Food stuffs Co., Ltd, Anhui University, Hefei, 230601, Anhui, People's Republic of China.
    Zhang B; Institutes of Physical Science and Information Technology, Anhui University, Hefei, 230601, Anhui, People's Republic of China. .
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    Źródło:
    Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2019 Sep; Vol. 103 (17), pp. 7085-7095. Date of Electronic Publication: 2019 Jul 10.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Cell Engineering*
    Deubiquitinating Enzyme CYLD/*genetics
    Immunoglobulin G/*biosynthesis
    MicroRNAs/*genetics
    3' Untranslated Regions ; Animals ; Antibodies, Bispecific/biosynthesis ; CHO Cells ; Cell Survival/genetics ; Cricetinae ; Cricetulus ; Deubiquitinating Enzyme CYLD/metabolism ; Down-Regulation ; Gene Expression ; MicroRNAs/antagonists & inhibitors ; Transcription Factor RelA/metabolism ; Wnt Signaling Pathway ; beta Catenin/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    CBX2 is a functional target of miRNA let-7a and acts as a tumor promoter in osteosarcoma.
    Autorzy:
    Han Q; Department of Bone and Soft Tissue, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
    Li C; Department of Bone and Soft Tissue, The Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, China.
    Cao Y; Key Laboratory of Clinical Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
    Bao J; Key Laboratory of Clinical Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
    Li K; Department of Hematology, Yinzhou People's Hospital affiliated to Medical College of Ningbo University, Ningbo, China.
    Song R; Department of Bone and Soft Tissue, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
    Chen X; Key Laboratory of Clinical Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
    Li J; Key Laboratory of Clinical Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
    Wu X; Department of Bone and Soft Tissue, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.; Department of Bone and Soft Tissue, The Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, China.; Key Laboratory of Clinical Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
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    Źródło:
    Cancer medicine [Cancer Med] 2019 Jul; Vol. 8 (8), pp. 3981-3991. Date of Electronic Publication: 2019 May 31.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Gene Expression Regulation, Neoplastic*
    Oncogenes*
    Bone Neoplasms/*genetics
    MicroRNAs/*genetics
    Osteosarcoma/*genetics
    Polycomb Repressive Complex 1/*genetics
    Aged ; Aged, 80 and over ; Animals ; Bone Neoplasms/diagnosis ; Bone Neoplasms/mortality ; Bone Neoplasms/therapy ; Cell Line, Tumor ; Disease Models, Animal ; Disease Progression ; Female ; Gene Expression Profiling ; Gene Silencing ; Humans ; Immunohistochemistry ; Male ; Mice ; Middle Aged ; Models, Biological ; Neoplasm Metastasis ; Neoplasm Staging ; Osteosarcoma/diagnosis ; Osteosarcoma/mortality ; Osteosarcoma/therapy ; Polycomb Repressive Complex 1/metabolism ; Prognosis ; RNA Interference
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    MiR-195-5p Promotes Cardiomyocyte Hypertrophy by Targeting MFN2 and FBXW7.
    Autorzy:
    Wang L; Shanxi Medical University, Taiyuan 030001, Shanxi, China.; The Affiliated Cardiovascular Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi, China.
    Qin D; Shanxi Medical University, Taiyuan 030001, Shanxi, China.; Department of Cardiology, The First Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi, China.
    Shi H; Shanxi Medical University, Taiyuan 030001, Shanxi, China.; Department of Cardiology, The First Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi, China.
    Zhang Y; Shanxi Medical University, Taiyuan 030001, Shanxi, China.
    Li H; Shanxi Medical University, Taiyuan 030001, Shanxi, China.; Department of Cardiology, The First Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi, China.
    Han Q; Shanxi Medical University, Taiyuan 030001, Shanxi, China.; Department of Cardiology, The First Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi, China.
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    Źródło:
    BioMed research international [Biomed Res Int] 2019 Jun 25; Vol. 2019, pp. 1580982. Date of Electronic Publication: 2019 Jun 25 (Print Publication: 2019).
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Gene Expression Regulation*
    Cardiomegaly/*metabolism
    F-Box-WD Repeat-Containing Protein 7/*antagonists & inhibitors
    GTP Phosphohydrolases/*biosynthesis
    MicroRNAs/*metabolism
    Myocytes, Cardiac/*metabolism
    Angiotensin II/adverse effects ; Angiotensin II/pharmacology ; Animals ; Cardiomegaly/chemically induced ; Cardiomegaly/pathology ; Male ; Mice ; Myocytes, Cardiac/pathology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    MiR-139-5p is associated with poor prognosis and regulates glycolysis by repressing PKM2 in gallbladder carcinoma.
    Autorzy:
    Chen J; Precision Medicine Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.; Key Laboratory of Clinical Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
    Yu Y; Precision Medicine Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.; Key Laboratory of Clinical Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
    Chen X; Precision Medicine Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.; Key Laboratory of Clinical Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
    He Y; Precision Medicine Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.; Key Laboratory of Clinical Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
    Hu Q; Precision Medicine Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.; Key Laboratory of Clinical Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
    Li H; Key Laboratory of Clinical Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
    Han Q; Key Laboratory of Clinical Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
    Ren F; Key Laboratory of Clinical Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
    Li J; Precision Medicine Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.; Key Laboratory of Clinical Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
    Li C; Department of Bone and Soft Tissue, The Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, China.
    Bao J; Key Laboratory of Clinical Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
    Ren Z; Precision Medicine Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.; Key Laboratory of Clinical Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
    Duan Z; Department of Orthopedic Surgery, David Geffen School of Medicine at UCLA Los Angeles, Los Angeles, California.
    Cui G; Precision Medicine Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.; Key Laboratory of Clinical Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
    Sun R; Precision Medicine Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.; Key Laboratory of Clinical Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
    Pokaż więcej
    Źródło:
    Cell proliferation [Cell Prolif] 2018 Dec; Vol. 51 (6), pp. e12510. Date of Electronic Publication: 2018 Aug 13.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Carrier Proteins/*genetics
    Gallbladder Neoplasms/*genetics
    Glycolysis/*genetics
    Membrane Proteins/*genetics
    MicroRNAs/*genetics
    Thyroid Hormones/*genetics
    Adult ; Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation/genetics ; Disease Progression ; Female ; Gallbladder Neoplasms/diagnosis ; Gene Expression Regulation, Neoplastic/genetics ; Humans ; Male ; MicroRNAs/metabolism ; Middle Aged ; Thyroid Hormone-Binding Proteins
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Histone demethylase PHF8 accelerates the progression of colorectal cancer and can be regulated by miR-488 in vitro.
    Autorzy:
    Lv Y; Department of Oncology, Chinese PLA General Hospital, Beijing 100853, P.R. China.
    Shi Y; Department of Oncology, Chinese PLA General Hospital, Beijing 100853, P.R. China.
    Han Q; Department of Oncology, Chinese PLA General Hospital, Beijing 100853, P.R. China.
    Dai G; Department of Oncology, Chinese PLA General Hospital, Beijing 100853, P.R. China.
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    Źródło:
    Molecular medicine reports [Mol Med Rep] 2017 Oct; Vol. 16 (4), pp. 4437-4444. Date of Electronic Publication: 2017 Aug 01.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Gene Expression Regulation, Neoplastic*
    Colorectal Neoplasms/*genetics
    Colorectal Neoplasms/*pathology
    Histone Demethylases/*genetics
    MicroRNAs/*genetics
    Transcription Factors/*genetics
    3' Untranslated Regions ; Adult ; Aged ; Apoptosis/genetics ; Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation ; Cell Survival/genetics ; Colorectal Neoplasms/mortality ; Colorectal Neoplasms/therapy ; Disease Progression ; Female ; Humans ; Kaplan-Meier Estimate ; Male ; Middle Aged ; Neoplasm Metastasis ; Neoplasm Staging ; Prognosis ; RNA Interference
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Extract of Spatholobus suberctus Dunn ameliorates ischemia-induced injury by targeting miR-494.
    Autorzy:
    Song S; Yantai Yuhuangding Hospital of Qingdao University Medical College, Yantai, Shandong, China.
    Lin F; Yantai Yuhuangding Hospital of Qingdao University Medical College, Yantai, Shandong, China.
    Zhu P; Yantai Hospital of Traditional Chinese Medicine, Yantai, Shandong, China.
    Wu C; Yantai Hospital of Traditional Chinese Medicine, Yantai, Shandong, China.
    Zhao S; Yantai Yuhuangding Hospital of Qingdao University Medical College, Yantai, Shandong, China.
    Han Q; Yantai Blood Center, Yantai, Shandong, China.
    Li X; Affiliated Hospital of Zunyi Medical College, Zunyi, Guizhou, China.
    Pokaż więcej
    Źródło:
    PloS one [PLoS One] 2017 Sep 07; Vol. 12 (9), pp. e0184348. Date of Electronic Publication: 2017 Sep 07 (Print Publication: 2017).
    Typ publikacji:
    Journal Article; Retracted Publication
    MeSH Terms:
    Brain Ischemia/*drug therapy
    Fabaceae/*chemistry
    MicroRNAs/*metabolism
    Plant Exudates/*therapeutic use
    Animals ; Apoptosis/drug effects ; Blotting, Western ; Brain Ischemia/genetics ; Brain Ischemia/metabolism ; Cell Survival/drug effects ; Male ; MicroRNAs/genetics ; PC12 Cells ; Plant Exudates/chemistry ; Rats ; Rats, Sprague-Dawley ; Reverse Transcriptase Polymerase Chain Reaction ; Sincalide/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    miR-216a rescues dexamethasone suppression of osteogenesis, promotes osteoblast differentiation and enhances bone formation, by regulating c-Cbl-mediated PI3K/AKT pathway.
    Autorzy:
    Li H; Department of Cell Biology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Peking Union Medical College Hospital, Center of Excellence in Tissue Engineering Chinese Academy of Medical Sciences, Beijing, China.
    Li T; Department of Cell Biology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Peking Union Medical College Hospital, Center of Excellence in Tissue Engineering Chinese Academy of Medical Sciences, Beijing, China.
    Fan J; Department of Cell Biology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Peking Union Medical College Hospital, Center of Excellence in Tissue Engineering Chinese Academy of Medical Sciences, Beijing, China.
    Li T; Department of Orthopaedic Surgery, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing, 100730, China.
    Fan L; Department of Cell Biology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Peking Union Medical College Hospital, Center of Excellence in Tissue Engineering Chinese Academy of Medical Sciences, Beijing, China.
    Wang S; Department of Cell Biology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Peking Union Medical College Hospital, Center of Excellence in Tissue Engineering Chinese Academy of Medical Sciences, Beijing, China.
    Weng X; Department of Orthopaedic Surgery, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing, 100730, China.
    Han Q; Department of Cell Biology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Peking Union Medical College Hospital, Center of Excellence in Tissue Engineering Chinese Academy of Medical Sciences, Beijing, China.
    Zhao RC; Department of Cell Biology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Peking Union Medical College Hospital, Center of Excellence in Tissue Engineering Chinese Academy of Medical Sciences, Beijing, China.
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    Źródło:
    Cell death and differentiation [Cell Death Differ] 2015 Dec; Vol. 22 (12), pp. 1935-45. Date of Electronic Publication: 2015 Jul 24.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Cell Differentiation/*drug effects
    Dexamethasone/*pharmacology
    MicroRNAs/*metabolism
    Osteoblasts/*drug effects
    Osteogenesis/*drug effects
    Proto-Oncogene Proteins c-cbl/*metabolism
    Signal Transduction/*drug effects
    Adipose Tissue/cytology ; Animals ; Base Sequence ; Cells, Cultured ; Down-Regulation ; Humans ; Mice ; Mice, Inbred NOD ; Mice, SCID ; MicroRNAs/antagonists & inhibitors ; MicroRNAs/genetics ; Osteoblasts/cytology ; Phosphatidylinositol 3-Kinase/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Proto-Oncogene Proteins c-cbl/antagonists & inhibitors ; Proto-Oncogene Proteins c-cbl/genetics ; Sequence Alignment ; Stem Cell Transplantation ; Stem Cells/cytology ; Stem Cells/metabolism ; Umbilical Cord/cytology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    α-Melanocyte-stimulating hormone prevents glutamate excitotoxicity in developing chicken retina via MC4R-mediated down-regulation of microRNA-194.
    Autorzy:
    Zhang Y; Tianjin Medical University Eye Hospital, Tianjin Medical University Eye Institute, College of Optometry and Ophthalmology, Tianjin Medical University, Tianjin, 300384, China.
    Bo Q; Tianjin Medical University Eye Hospital, Tianjin Medical University Eye Institute, College of Optometry and Ophthalmology, Tianjin Medical University, Tianjin, 300384, China.
    Wu W; Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai University, Tianjin, 300071, China.
    Xu C; Institute of Radiation Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin Key Laboratory of Molecular Nuclear Medicine, Tianjin, 300192, China.
    Yu G; Tianjin Medical University Eye Hospital, Tianjin Medical University Eye Institute, College of Optometry and Ophthalmology, Tianjin Medical University, Tianjin, 300384, China.
    Ma S; Tianjin Medical University Eye Hospital, Tianjin Medical University Eye Institute, College of Optometry and Ophthalmology, Tianjin Medical University, Tianjin, 300384, China.
    Yang Q; Tianjin Medical University Eye Hospital, Tianjin Medical University Eye Institute, College of Optometry and Ophthalmology, Tianjin Medical University, Tianjin, 300384, China.
    Cao Y; Department of Cardiology, Gansu Provincial Hospital, Lanzhou, Gansu Province, 730000, China.
    Han Q; Tangshan Eye Hospital, Tangshan, Hebei Province, 063000, China.
    Ru Y; Tianjin Medical University Eye Hospital, Tianjin Medical University Eye Institute, College of Optometry and Ophthalmology, Tianjin Medical University, Tianjin, 300384, China.
    Liu X; Tianjin Medical University Eye Hospital, Tianjin Medical University Eye Institute, College of Optometry and Ophthalmology, Tianjin Medical University, Tianjin, 300384, China.
    Hua Wei R; Tianjin Medical University Eye Hospital, Tianjin Medical University Eye Institute, College of Optometry and Ophthalmology, Tianjin Medical University, Tianjin, 300384, China.
    Wang FE; Tianjin Medical University Eye Hospital, Tianjin Medical University Eye Institute, College of Optometry and Ophthalmology, Tianjin Medical University, Tianjin, 300384, China.
    Zhang X; Tianjin Medical University Eye Hospital, Tianjin Medical University Eye Institute, College of Optometry and Ophthalmology, Tianjin Medical University, Tianjin, 300384, China.
    Li X; Tianjin Medical University Eye Hospital, Tianjin Medical University Eye Institute, College of Optometry and Ophthalmology, Tianjin Medical University, Tianjin, 300384, China.
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    Źródło:
    Scientific reports [Sci Rep] 2015 Oct 28; Vol. 5, pp. 15812. Date of Electronic Publication: 2015 Oct 28.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Down-Regulation/*physiology
    Glutamic Acid/*metabolism
    MicroRNAs/*metabolism
    Receptor, Melanocortin, Type 4/*metabolism
    alpha-MSH/*metabolism
    Animals ; Chick Embryo ; Chickens/metabolism ; Retina/metabolism ; Retinal Diseases/metabolism ; Signal Transduction/physiology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    MicroRNA-1246 enhances migration and invasion through CADM1 in hepatocellular carcinoma.
    Autorzy:
    Sun Z
    Meng C
    Wang S
    Zhou N
    Guan M
    Bai C
    Lu S
    Han Q; Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing, People's Republic of China. .
    Zhao RC
    Pokaż więcej
    Źródło:
    BMC cancer [BMC Cancer] 2014 Aug 27; Vol. 14, pp. 616. Date of Electronic Publication: 2014 Aug 27.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Carcinoma, Hepatocellular/*pathology
    Cell Adhesion Molecules/*metabolism
    Immunoglobulins/*metabolism
    Liver Neoplasms/*pathology
    MicroRNAs/*metabolism
    3' Untranslated Regions ; Carcinoma, Hepatocellular/metabolism ; Carcinoma, Hepatocellular/mortality ; Cell Adhesion Molecule-1 ; Cell Adhesion Molecules/genetics ; Cell Line, Tumor ; Cell Movement ; Gene Expression Regulation, Neoplastic ; Hep G2 Cells ; Humans ; Immunoglobulins/genetics ; Liver Neoplasms/metabolism ; Liver Neoplasms/mortality ; Neoplasm Invasiveness/genetics ; Neoplasm Invasiveness/pathology ; Risk Factors ; Survival Analysis
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Inducible microRNA-223 down-regulation promotes TLR-triggered IL-6 and IL-1β production in macrophages by targeting STAT3.
    Autorzy:
    Chen Q; Institute of Immunology, Zhejiang University School of Medicine, Hangzhou, People's Republic of China.
    Wang H
    Liu Y
    Song Y
    Lai L
    Han Q
    Cao X
    Wang Q
    Pokaż więcej
    Źródło:
    PloS one [PLoS One] 2012; Vol. 7 (8), pp. e42971. Date of Electronic Publication: 2012 Aug 24.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Interleukin-6/*metabolism
    Macrophages/*drug effects
    Macrophages/*metabolism
    MicroRNAs/*metabolism
    Tumor Necrosis Factor-alpha/*metabolism
    Animals ; Cell Line ; Interleukin-1beta/genetics ; Interleukin-1beta/metabolism ; Interleukin-6/genetics ; Lipopolysaccharides/pharmacology ; Mice ; MicroRNAs/genetics ; Poly I-C/pharmacology ; Tumor Necrosis Factor-alpha/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
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