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Tytuł:
Safety and immunogenicity of boosting with a severe acute respiratory syndrome coronavirus 2 omicron variant mRNA vaccine in healthy adults: An open-label, and single-arm Phase 1 study.
Autorzy:
Hannawi S; Internal Medicine Department, Al Kuwait-Dubai Hospital, Emirates Health Services (EHS), Ministry of Health and Prevention, Dubai, United Arab Emirates.
Zhang RR; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences (AMMS), Beijing, China.
Abuquta A; Accident and Emergency Department, Al Kuwait-Dubai Hospital, EHS, Ministry of Health and Prevention, Dubai, United Arab Emirates.
Safeldin L; General Surgery Department, Al Kuwait-Dubai Hospital, EHS, Ministry of Health and Prevention, Dubai, United Arab Emirates.
Hassan A; General Surgery Department, Al Kuwait-Dubai Hospital, EHS, Ministry of Health and Prevention, Dubai, United Arab Emirates.
Alamadi A; General Surgery Department, Al Kuwait-Dubai Hospital, EHS, Ministry of Health and Prevention, Dubai, United Arab Emirates.
Hossain T; General Surgery Department, Al Kuwait-Dubai Hospital, EHS, Ministry of Health and Prevention, Dubai, United Arab Emirates.
Mostafa M; PDC FZ-LLC, Contract Research Organization, Dubai, United Arab Emirates.
Ghoneim Y; PDC FZ-LLC, Contract Research Organization, Dubai, United Arab Emirates.
Solo J; PDC FZ-LLC, Contract Research Organization, Dubai, United Arab Emirates.
Zheng HX; Abogen Biosciences, Suzhou Abogen Biosciences Co., Ltd., Suzhou, China.
Wu DF; Abogen Biosciences, Suzhou Abogen Biosciences Co., Ltd., Suzhou, China.
Yu DD; Abogen Biosciences, Suzhou Abogen Biosciences Co., Ltd., Suzhou, China.
Yuan JC; Abogen Biosciences, Suzhou Abogen Biosciences Co., Ltd., Suzhou, China.
Zhao D; Abogen Biosciences, Suzhou Abogen Biosciences Co., Ltd., Suzhou, China.
Lin R; Abogen Biosciences, Suzhou Abogen Biosciences Co., Ltd., Suzhou, China.
Ying B; Abogen Biosciences, Suzhou Abogen Biosciences Co., Ltd., Suzhou, China.
Qin CF; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences (AMMS), Beijing, China.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2023 Aug; Vol. 13 (8), pp. e1387.
Typ publikacji:
Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
SARS-CoV-2*/genetics
COVID-19*/prevention & control
Humans ; Adult ; mRNA Vaccines
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł:
TRIM22 suppresses Zika virus replication by targeting NS1 and NS3 for proteasomal degradation.
Autorzy:
Zu S; Center for Systems Medicine, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100005, China.; Institute of Systems Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100005, China.; Suzhou Institute of Systems Medicine, Suzhou, 215123, Jiangsu, China.; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing, 100071, China.
Li C; Institute for Immunity, Transplantation and Infection, Department of Pathology, Department of Microbiology and Immunology, Stanford University, Stanford, CA, 94305, USA.
Li L; Institute of Systems Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100005, China.; Suzhou Institute of Systems Medicine, Suzhou, 215123, Jiangsu, China.
Deng YQ; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing, 100071, China.
Chen X; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing, 100071, China.
Luo D; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing, 100071, China.
Ye Q; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing, 100071, China.
Huang YJ; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing, 100071, China.
Li XF; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing, 100071, China.
Zhang RR; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing, 100071, China.
Sun N; Center for Systems Medicine, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100005, China.; Institute of Systems Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100005, China.; Suzhou Institute of Systems Medicine, Suzhou, 215123, Jiangsu, China.
Zhang X; Center for Systems Medicine, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100005, China.
Aliyari SR; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, CA, 90095, USA.
Nielsen-Saines K; Division of Pediatric Infectious Diseases, David Geffen School of Medicine, University of California, Los Angeles, CA, 90095, USA.
Jung JU; Department of Cancer Biology and Global Center for Pathogens Research and Human Health, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, 44195, USA.
Yang H; Institute of Systems Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100005, China. .; Suzhou Institute of Systems Medicine, Suzhou, 215123, Jiangsu, China. .
Qin CF; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing, 100071, China. .
Cheng G; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, CA, 90095, USA. .
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Źródło:
Cell & bioscience [Cell Biosci] 2022 Aug 30; Vol. 12 (1), pp. 139. Date of Electronic Publication: 2022 Aug 30.
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Antibody engineering improves neutralization activity against K417 spike mutant SARS-CoV-2 variants.
Autorzy:
Li L; Institute of Systems Medicine, Chinese Academy of Medical Science & Peking Union College, Beijing, 100005, China.; Suzhou Institute of Systems Medicine, Suzhou, 215123, China.
Gao M; Institute of Systems Medicine, Chinese Academy of Medical Science & Peking Union College, Beijing, 100005, China.; Suzhou Institute of Systems Medicine, Suzhou, 215123, China.
Jiao P; State Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, Tianjin, 300071, China.
Zu S; Institute of Systems Medicine, Chinese Academy of Medical Science & Peking Union College, Beijing, 100005, China.; Suzhou Institute of Systems Medicine, Suzhou, 215123, China.
Deng YQ; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, AMMS, Beijing, 100071, China.
Wan D; AtaGenix Laboratories (Wuhan) Co., Ltd, Wuhan, 430075, China.
Cao Y; Center of Growth, Metabolism and Aging, Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, 610065, China.
Duan J; AtaGenix Laboratories (Wuhan) Co., Ltd, Wuhan, 430075, China.
Aliyari SR; Department of Microbiology, Immunology & Molecular Genetics, University of California, Los Angeles, CA, 90095, USA.
Li J; Department of Laboratory Medicine, Taihe Hospital, Hubei University of Medicine, Shiyan, 442000, China.
Shi Y; Institute of Systems Medicine, Chinese Academy of Medical Science & Peking Union College, Beijing, 100005, China.; Suzhou Institute of Systems Medicine, Suzhou, 215123, China.
Rao Z; State Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, Tianjin, 300071, China.; Guangzhou Laboratory, B1, Standard Property Unite 4, Guangzhou international bio-island, Guangzhou, 510320, China.
Qin CF; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, AMMS, Beijing, 100071, China. chengfeng_qin@126.com.
Guo Y; State Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, Tianjin, 300071, China. .
Cheng G; Department of Microbiology, Immunology & Molecular Genetics, University of California, Los Angeles, CA, 90095, USA.
Yang H; Institute of Systems Medicine, Chinese Academy of Medical Science & Peking Union College, Beijing, 100005, China. .; Suzhou Institute of Systems Medicine, Suzhou, 215123, China. .
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Źródło:
Cell & bioscience [Cell Biosci] 2022 May 17; Vol. 12 (1), pp. 63. Date of Electronic Publication: 2022 May 17.
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Transient acquisition of cross-species infectivity during the evolution of SARS-CoV-2.
Autorzy:
Chen Q; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, AMMS, China.
Huang XY; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, AMMS, China.
Sun MX; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, AMMS, China.
Li RT; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, AMMS, China.
Gu H; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, AMMS, China.
Tian Y; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, AMMS, China.
Zhang RR; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, AMMS, China.
Luo D; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, AMMS, China.
Zhou C; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, AMMS, China.
Zhang Y; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, AMMS, China.
Cao T; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, AMMS, China.
Zhang NN; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, AMMS, China.
Deng YQ; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, AMMS, China.
Li XF; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, AMMS, China.
Qin CF; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, AMMS, China.
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Źródło:
National science review [Natl Sci Rev] 2021 Sep 04; Vol. 8 (11), pp. nwab167. Date of Electronic Publication: 2021 Sep 04 (Print Publication: 2021).
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Rapid Detection of Adulteration in Dendrobium huoshanense Using NIR Spectroscopy Coupled with Chemometric Methods.
Autorzy:
Hao JW; College of Biotechnology and Pharmaceutical Engineering, West Anhui University, Lu'an City 237012, China.
Chen Y; Institute of Pharmaceutical Science, China Pharmaceutical University, Tong Jia Xiang, Nanjing, Jiangsu 210009, China.
Chen ND; College of Biotechnology and Pharmaceutical Engineering, West Anhui University, Lu'an City 237012, China.; Anhui Engineering Laboratory for Conservation and Sustainable Utilization of Traditional Chinese Medicine Resource, Lu'an City 237012, China.
Qin CF; College of Biotechnology and Pharmaceutical Engineering, West Anhui University, Lu'an City 237012, China.
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Źródło:
Journal of AOAC International [J AOAC Int] 2021 Jun 12; Vol. 104 (3), pp. 854-859.
Typ publikacji:
Journal Article
MeSH Terms:
Dendrobium*
Spectroscopy, Near-Infrared*
Discriminant Analysis ; Drug Contamination ; Food Contamination/analysis ; Least-Squares Analysis
Czasopismo naukowe
Tytuł:
A proof of concept for neutralizing antibody-guided vaccine design against SARS-CoV-2.
Autorzy:
Zhang L; National Health Commission of the People's Republic of China, Key Laboratory of Enteric Pathogenic Microbiology (Jiangsu Provincial Center for Disease Control and Prevention), Nanjing 210009, China.
Cao L; CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Gao XS; Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing 211166, China.
Zheng BY; National Health Commission of the People's Republic of China, Key Laboratory of Enteric Pathogenic Microbiology (Jiangsu Provincial Center for Disease Control and Prevention), Nanjing 210009, China.
Deng YQ; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
Li JX; National Health Commission of the People's Republic of China, Key Laboratory of Enteric Pathogenic Microbiology (Jiangsu Provincial Center for Disease Control and Prevention), Nanjing 210009, China.
Feng R; CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Bian Q; National Health Commission of the People's Republic of China, Key Laboratory of Enteric Pathogenic Microbiology (Jiangsu Provincial Center for Disease Control and Prevention), Nanjing 210009, China.
Guo XL; National Health Commission of the People's Republic of China, Key Laboratory of Enteric Pathogenic Microbiology (Jiangsu Provincial Center for Disease Control and Prevention), Nanjing 210009, China.
Wang N; CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Qiu HY; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
Wang L; CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Cui Z; CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Ye Q; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
Chen G; National Health Commission of the People's Republic of China, Key Laboratory of Enteric Pathogenic Microbiology (Jiangsu Provincial Center for Disease Control and Prevention), Nanjing 210009, China.
Lu KK; National Health Commission of the People's Republic of China, Key Laboratory of Enteric Pathogenic Microbiology (Jiangsu Provincial Center for Disease Control and Prevention), Nanjing 210009, China.
Chen Y; National Health Commission of the People's Republic of China, Key Laboratory of Enteric Pathogenic Microbiology (Jiangsu Provincial Center for Disease Control and Prevention), Nanjing 210009, China.
Chen YT; CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Pan HX; National Health Commission of the People's Republic of China, Key Laboratory of Enteric Pathogenic Microbiology (Jiangsu Provincial Center for Disease Control and Prevention), Nanjing 210009, China.
Yu J; Jiangsu Rec-biotechnology Co. Ltd, Taizhou 225300, China.
Yao W; Jiangsu Rec-biotechnology Co. Ltd, Taizhou 225300, China.
Zhu BL; National Health Commission of the People's Republic of China, Key Laboratory of Enteric Pathogenic Microbiology (Jiangsu Provincial Center for Disease Control and Prevention), Nanjing 210009, China.
Chen J; Jiangsu Rec-biotechnology Co. Ltd, Taizhou 225300, China.
Liu Y; Jiangsu Rec-biotechnology Co. Ltd, Taizhou 225300, China.
Qin CF; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
Wang X; CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Zhu FC; National Health Commission of the People's Republic of China, Key Laboratory of Enteric Pathogenic Microbiology (Jiangsu Provincial Center for Disease Control and Prevention), Nanjing 210009, China.
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Źródło:
National science review [Natl Sci Rev] 2021 Mar 27; Vol. 8 (8), pp. nwab053. Date of Electronic Publication: 2021 Mar 27 (Print Publication: 2021).
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Double lock of a potent human therapeutic monoclonal antibody against SARS-CoV-2.
Autorzy:
Zhu L; CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Deng YQ; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Zhang RR; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Cui Z; CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Sun CY; Beijing Engineering Research Center of Protein and Antibody, Sinocelltech Ltd., Beijing 100176, China.
Fan CF; Division of Animal Model Research, Institute for Laboratory Animal Resources, National Institutes for Food and Drug Control (NIFDC), Beijing 102629, China.
Xing X; CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Huang W; Division of HIV/AIDS and Sex-Transmitted Virus Vaccines, Institute for Biological Product Control, NIFDC, Beijing 102629, China.
Chen Q; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Zhang NN; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Ye Q; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Cao TS; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Wang N; CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Wang L; CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Cao L; CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Wang H; Beijing Engineering Research Center of Protein and Antibody, Sinocelltech Ltd., Beijing 100176, China.
Kong D; Beijing Engineering Research Center of Protein and Antibody, Sinocelltech Ltd., Beijing 100176, China.
Ma J; Beijing Engineering Research Center of Protein and Antibody, Sinocelltech Ltd., Beijing 100176, China.
Luo C; Beijing Engineering Research Center of Protein and Antibody, Sinocelltech Ltd., Beijing 100176, China.
Zhang Y; Beijing Engineering Research Center of Protein and Antibody, Sinocelltech Ltd., Beijing 100176, China.
Nie J; Division of HIV/AIDS and Sex-Transmitted Virus Vaccines, Institute for Biological Product Control, NIFDC, Beijing 102629, China.
Sun Y; CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Lv Z; CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Shaw N; CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Li Q; Division of HIV/AIDS and Sex-Transmitted Virus Vaccines, Institute for Biological Product Control, NIFDC, Beijing 102629, China.
Li XF; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Hu J; CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Xie L; Beijing Engineering Research Center of Protein and Antibody, Sinocelltech Ltd., Beijing 100176, China.
Rao Z; CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Wang Y; Division of HIV/AIDS and Sex-Transmitted Virus Vaccines, Institute for Biological Product Control, NIFDC, Beijing 102629, China.
Wang X; CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Qin CF; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
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Źródło:
National science review [Natl Sci Rev] 2020 Dec 18; Vol. 8 (3), pp. nwaa297. Date of Electronic Publication: 2020 Dec 18 (Print Publication: 2021).
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Adaptation of SARS-CoV-2 in BALB/c mice for testing vaccine efficacy.
Autorzy:
Gu H; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Chen Q; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Yang G; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing 102206, China.
He L; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Fan H; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Deng YQ; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Wang Y; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing 102206, China.
Teng Y; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Zhao Z; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Cui Y; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Li Y; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Li XF; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Li J; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Zhang NN; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Yang X; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Chen S; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Guo Y; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Zhao G; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Wang X; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Luo DY; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Wang H; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
Yang X; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing 102206, China.
Li Y; Institute of Military Cognition and Brain Sciences, Beijing 100850, China.
Han G; Institute of Military Cognition and Brain Sciences, Beijing 100850, China.
He Y; Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.
Zhou X; Laboratory Animal Center, Academy of Military Medical Sciences, Beijing 100071, China.
Geng S; Beijing JOINN Biologics Co., Beijing 100176, China.
Sheng X; Beijing JOINN Biologics Co., Beijing 100176, China.
Jiang S; Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Fudan University, Shanghai 200032, China. .
Sun S; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China. .
Qin CF; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China. .
Zhou Y; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China.
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Źródło:
Science (New York, N.Y.) [Science] 2020 Sep 25; Vol. 369 (6511), pp. 1603-1607. Date of Electronic Publication: 2020 Jul 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Disease Models, Animal*
Mice*
Betacoronavirus/*immunology
Coronavirus Infections/*prevention & control
Pandemics/*prevention & control
Pneumonia, Viral/*prevention & control
Viral Vaccines/*immunology
Administration, Intranasal ; Angiotensin-Converting Enzyme 2 ; Animals ; Betacoronavirus/genetics ; Betacoronavirus/pathogenicity ; COVID-19 ; COVID-19 Vaccines ; Coronavirus Infections/immunology ; Female ; High-Throughput Nucleotide Sequencing ; Humans ; Immunogenicity, Vaccine ; Lung/virology ; Lung Diseases, Interstitial/virology ; Mice, Inbred BALB C ; Mice, Transgenic ; Mutation ; Peptidyl-Dipeptidase A/genetics ; SARS-CoV-2 ; Spike Glycoprotein, Coronavirus/genetics ; Vaccines, Synthetic/administration & dosage ; Vaccines, Synthetic/immunology ; Viral Vaccines/administration & dosage ; Virulence/genetics
Czasopismo naukowe
Tytuł:
Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody.
Autorzy:
Lv Z; CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.; University of Chinese Academy of Sciences, Beijing 100049, China.
Deng YQ; State Key Laboratory of Pathogen and Biosecurity, Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing, China.
Ye Q; State Key Laboratory of Pathogen and Biosecurity, Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing, China.
Cao L; CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Sun CY; Beijing Protein and Antibody R&D Engineering Center, Sinocelltech Ltd., Beijing 100176, China.
Fan C; Division of Animal Model Research, Institute for Laboratory Animal Resources, National Institutes for Food and Drug Control (NIFDC), Beijing 102629, China.
Huang W; Division of HIV/AIDS and Sex-Transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), Beijing 102629, China.
Sun S; State Key Laboratory of Pathogen and Biosecurity, Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing, China.
Sun Y; CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Zhu L; CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Chen Q; State Key Laboratory of Pathogen and Biosecurity, Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing, China.
Wang N; CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.; University of Chinese Academy of Sciences, Beijing 100049, China.
Nie J; Division of HIV/AIDS and Sex-Transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), Beijing 102629, China.
Cui Z; CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.; University of Chinese Academy of Sciences, Beijing 100049, China.
Zhu D; CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Shaw N; CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Li XF; State Key Laboratory of Pathogen and Biosecurity, Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing, China.
Li Q; Division of HIV/AIDS and Sex-Transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), Beijing 102629, China.
Xie L; Beijing Protein and Antibody R&D Engineering Center, Sinocelltech Ltd., Beijing 100176, China. .; Beijing Antibody Research Key Laboratory, Sino Biological Inc., Building 9, Jing Dong Bei Technology Park, No.18 Ke Chuang 10th St, BDA, Beijing, 100176, China.; Cell Culture Engineering Center, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China.
Wang Y; Division of HIV/AIDS and Sex-Transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), Beijing 102629, China. .
Rao Z; CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China. .
Qin CF; State Key Laboratory of Pathogen and Biosecurity, Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing, China. .
Wang X; CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China. .; University of Chinese Academy of Sciences, Beijing 100049, China.
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Źródło:
Science (New York, N.Y.) [Science] 2020 Sep 18; Vol. 369 (6510), pp. 1505-1509. Date of Electronic Publication: 2020 Jul 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antibodies, Monoclonal, Humanized/*chemistry
Antibodies, Neutralizing/*chemistry
Betacoronavirus/*immunology
Peptidyl-Dipeptidase A/*immunology
Receptors, Virus/*immunology
Severe acute respiratory syndrome-related coronavirus/*immunology
Angiotensin-Converting Enzyme 2 ; Animals ; Antibodies, Monoclonal, Humanized/therapeutic use ; Antibodies, Neutralizing/therapeutic use ; COVID-19 ; Chlorocebus aethiops ; Coronavirus Infections/therapy ; Epitope Mapping ; Humans ; Immunoglobulin Fab Fragments/chemistry ; Lung/immunology ; Mice ; Pandemics ; Pneumonia, Viral/therapy ; Protein Domains ; Protein Multimerization ; SARS-CoV-2 ; Vero Cells
Czasopismo naukowe
Tytuł:
Susceptibility of Armigeres subalbatus Coquillett (Diptera: Culicidae) to Zika virus through oral and urine infection.
Autorzy:
Li CX; Department of Vector Biology and Control, State Key Laboratory of Pathogen and Biosecurity, Institute of Microbiology and Epidemiology, Beijing, China.
Guo XX; Department of Vector Biology and Control, State Key Laboratory of Pathogen and Biosecurity, Institute of Microbiology and Epidemiology, Beijing, China.
Deng YQ; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Institute of Microbiology and Epidemiology, Beijing, China.
Liu QM; Department of Vector Biology and Control, State Key Laboratory of Pathogen and Biosecurity, Institute of Microbiology and Epidemiology, Beijing, China.
Xing D; Department of Vector Biology and Control, State Key Laboratory of Pathogen and Biosecurity, Institute of Microbiology and Epidemiology, Beijing, China.
Sun AJ; Department of Vector Biology and Control, State Key Laboratory of Pathogen and Biosecurity, Institute of Microbiology and Epidemiology, Beijing, China.
Wu Q; Department of Vector Biology and Control, State Key Laboratory of Pathogen and Biosecurity, Institute of Microbiology and Epidemiology, Beijing, China.
Dong YD; Department of Vector Biology and Control, State Key Laboratory of Pathogen and Biosecurity, Institute of Microbiology and Epidemiology, Beijing, China.
Zhang YM; Department of Vector Biology and Control, State Key Laboratory of Pathogen and Biosecurity, Institute of Microbiology and Epidemiology, Beijing, China.
Zhang HD; Department of Vector Biology and Control, State Key Laboratory of Pathogen and Biosecurity, Institute of Microbiology and Epidemiology, Beijing, China.
Cao WC; Department of Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Institute of Microbiology and Epidemiology, Beijing, China.
Qin CF; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Institute of Microbiology and Epidemiology, Beijing, China.
Zhao TY; Department of Vector Biology and Control, State Key Laboratory of Pathogen and Biosecurity, Institute of Microbiology and Epidemiology, Beijing, China.
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Źródło:
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2020 Jul 06; Vol. 14 (7), pp. e0008450. Date of Electronic Publication: 2020 Jul 06 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Culicidae/*virology
Mosquito Vectors/*virology
Zika Virus/*physiology
Zika Virus Infection/*transmission
Animals ; Culicidae/growth & development ; Culicidae/physiology ; Female ; Humans ; Larva/virology ; Mice ; Mosquito Vectors/growth & development ; Mosquito Vectors/physiology ; Saliva/virology ; Zika Virus/genetics ; Zika Virus/isolation & purification ; Zika Virus Infection/urine ; Zika Virus Infection/virology
Czasopismo naukowe
Tytuł:
Aedes aegypti HPX8C modulates immune responses against viral infection.
Autorzy:
Wang JM; State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
Cheng Y; State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China.
Shi ZK; State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China.
Li XF; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.; Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, China.
Xing LS; State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
Jiang H; State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
Wen D; State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
Deng YQ; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
Zheng AH; State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China.
Qin CF; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.; Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, China.
Zou Z; State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China.
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Źródło:
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2019 Apr 15; Vol. 13 (4), pp. e0007287. Date of Electronic Publication: 2019 Apr 15 (Print Publication: 2019).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Immunity, Innate*
Aedes/*genetics
Aedes/*immunology
Peroxidase/*genetics
Aedes/virology ; Animals ; Antimicrobial Cationic Peptides/genetics ; Dengue/immunology ; Dengue Virus ; Digestive System/immunology ; Digestive System/virology ; Gene Expression Profiling ; Gene Expression Regulation ; Heme/genetics ; Heme/immunology ; Host Microbial Interactions ; Mice ; Peroxidase/immunology ; RNA Interference ; Reactive Oxygen Species/metabolism ; Real-Time Polymerase Chain Reaction ; Signal Transduction ; Specific Pathogen-Free Organisms ; Toll-Like Receptors/genetics
Czasopismo naukowe
Tytuł:
Characterization of a candidate tetravalent vaccine based on 2'-O-methyltransferase mutants.
Autorzy:
Züst R; Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore.
Li SH; Novartis Institute for Tropical Diseases, Chromos, Singapore, Singapore.; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
Xie X; Novartis Institute for Tropical Diseases, Chromos, Singapore, Singapore.; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX, United States of America.
Velumani S; Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore.
Chng M; Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore.
Toh YX; Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore.
Zou J; Novartis Institute for Tropical Diseases, Chromos, Singapore, Singapore.; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX, United States of America.
Dong H; Novartis Institute for Tropical Diseases, Chromos, Singapore, Singapore.
Shan C; Novartis Institute for Tropical Diseases, Chromos, Singapore, Singapore.; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX, United States of America.
Pang J; Biological Resource Centre, Agency for Science, Technology and Research, Singapore, Singapore.
Qin CF; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
Newell EW; Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore.
Shi PY; Novartis Institute for Tropical Diseases, Chromos, Singapore, Singapore.; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX, United States of America.; Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, TX, United States of America.; Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch, Galveston, TX, United States of America.
Fink K; Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore.
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Źródło:
PloS one [PLoS One] 2018 Jan 03; Vol. 13 (1), pp. e0189262. Date of Electronic Publication: 2018 Jan 03 (Print Publication: 2018).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Mutation*
Dengue Vaccines/*immunology
Dengue Virus/*immunology
Methyltransferases/*genetics
Animals ; Antibodies, Neutralizing/analysis ; Antibodies, Neutralizing/immunology ; Cell Line ; Enzyme-Linked Immunosorbent Assay ; Female ; Humans ; Macaca fascicularis ; Male ; Mice
Czasopismo naukowe
Tytuł:
A single mutation in the prM protein of Zika virus contributes to fetal microcephaly.
Autorzy:
Yuan L; State Key Laboratory of Molecular Developmental Biology, Chinese Academy of Sciences (CAS) Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, CAS, Beijing 100101, China.; University of CAS, Beijing 100101, China.
Huang XY; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
Liu ZY; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
Zhang F; State Key Laboratory of Molecular Developmental Biology, Chinese Academy of Sciences (CAS) Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, CAS, Beijing 100101, China.; University of CAS, Beijing 100101, China.
Zhu XL; State Key Laboratory of Molecular Developmental Biology, Chinese Academy of Sciences (CAS) Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, CAS, Beijing 100101, China.; University of CAS, Beijing 100101, China.
Yu JY; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
Ji X; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
Xu YP; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
Li G; State Key Laboratory of Molecular Developmental Biology, Chinese Academy of Sciences (CAS) Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, CAS, Beijing 100101, China.; University of CAS, Beijing 100101, China.
Li C; State Key Laboratory of Molecular Developmental Biology, Chinese Academy of Sciences (CAS) Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, CAS, Beijing 100101, China.; University of CAS, Beijing 100101, China.
Wang HJ; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
Deng YQ; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
Wu M; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, CAS, Beijing 100101, China.
Cheng ML; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.; Graduate School, Anhui Medical University, Hefei 230032, China.
Ye Q; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
Xie DY; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.; Graduate School, Anhui Medical University, Hefei 230032, China.
Li XF; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
Wang X; National Laboratory of Macromolecules, Institute of Biophysics, CAS, Beijing 100101, China.
Shi W; Shandong Universities Key Laboratory of Etiology and Epidemiology of Emerging Infectious Diseases, Taishan Medical College, Taian 271000, China.
Hu B; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, CAS, Beijing 100101, China.
Shi PY; Department of Biochemistry and Molecular Biology and Department of Pharmacology and Toxicology, Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch, Galveston, TX 77555, USA.
Xu Z; State Key Laboratory of Molecular Developmental Biology, Chinese Academy of Sciences (CAS) Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, CAS, Beijing 100101, China.; University of CAS, Beijing 100101, China.; Parkinson's Disease Center, Beijing Institute for Brain Disorders, Beijing 100101, China.
Qin CF; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China.
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Źródło:
Science (New York, N.Y.) [Science] 2017 Nov 17; Vol. 358 (6365), pp. 933-936. Date of Electronic Publication: 2017 Sep 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Microcephaly/*virology
Viral Envelope Proteins/*genetics
Zika Virus/*genetics
Zika Virus/*pathogenicity
Zika Virus Infection/*virology
Americas/epidemiology ; Amino Acid Substitution ; Animals ; Asparagine/genetics ; Cell Line, Tumor ; Cricetinae ; Disease Outbreaks ; Humans ; Incidence ; Mice ; Microcephaly/epidemiology ; Mutation ; Neural Stem Cells/virology ; Polynesia/epidemiology ; Serine/genetics ; Zika Virus Infection/complications ; Zika Virus Infection/epidemiology
Czasopismo naukowe
Tytuł:
Protein Restriction with Amino Acid-Balanced Diets Shrinks Circulating Pool Size of Amino Acid by Decreasing Expression of Specific Transporters in the Small Intestine.
Autorzy:
Qiu K; State Key Lab of Animal Nutrition & Ministry of Agriculture Feed Industry Centre, College of Animal Science & Technology, China Agricultural University, Beijing, 100193, China.
Qin CF; State Key Lab of Animal Nutrition & Ministry of Agriculture Feed Industry Centre, College of Animal Science & Technology, China Agricultural University, Beijing, 100193, China.
Luo M; Chongqing Academy of Animal Science, Rongchang, Chongqing, 450023, China.
Zhang X; State Key Lab of Animal Nutrition & Ministry of Agriculture Feed Industry Centre, College of Animal Science & Technology, China Agricultural University, Beijing, 100193, China.
Sun WJ; State Key Lab of Animal Nutrition & Ministry of Agriculture Feed Industry Centre, College of Animal Science & Technology, China Agricultural University, Beijing, 100193, China.
Jiao N; State Key Lab of Animal Nutrition & Ministry of Agriculture Feed Industry Centre, College of Animal Science & Technology, China Agricultural University, Beijing, 100193, China.
Li de F; State Key Lab of Animal Nutrition & Ministry of Agriculture Feed Industry Centre, College of Animal Science & Technology, China Agricultural University, Beijing, 100193, China.
Yin JD; State Key Lab of Animal Nutrition & Ministry of Agriculture Feed Industry Centre, College of Animal Science & Technology, China Agricultural University, Beijing, 100193, China.
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Źródło:
PloS one [PLoS One] 2016 Sep 09; Vol. 11 (9), pp. e0162475. Date of Electronic Publication: 2016 Sep 09 (Print Publication: 2016).
Typ publikacji:
Journal Article
MeSH Terms:
Amino Acids/*pharmacology
Intestine, Small/*metabolism
Animal Feed ; Animals ; Blotting, Western ; Body Weight/drug effects ; Eating/drug effects ; Intestine, Small/drug effects ; Jejunum/drug effects ; Jejunum/metabolism ; Models, Theoretical ; Nitrogen/metabolism ; Swine
Czasopismo naukowe
Tytuł:
Adenosine Analog NITD008 Is a Potent Inhibitor of Zika Virus.
Autorzy:
Deng YQ; Department of Virology, Beijing Institute of Microbiology and Epidemiology; State Key Laboratory of Pathogen and Biosecurity, Beijing.
Zhang NN; Department of Virology, Beijing Institute of Microbiology and Epidemiology; Guangxi Medical University, Nanning.
Li CF; Center for Systems Medicine, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing; Suzhou Institute of Systems Medicine, Jiangsu.
Tian M; Beijing Traditional Medicine Chinese Hospital, Capital Medical University.
Hao JN; Department of Virology, Beijing Institute of Microbiology and Epidemiology; Anhui Medical University, Hefei, China.
Xie XP; Department of Biochemistry and Molecular Biology, Department of Pharmacology and Toxicology , Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch , Galveston.
Shi PY; Department of Biochemistry and Molecular Biology, Department of Pharmacology and Toxicology , Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch , Galveston.
Qin CF; Department of Virology, Beijing Institute of Microbiology and Epidemiology; State Key Laboratory of Pathogen and Biosecurity, Beijing; Guangxi Medical University, Nanning; Anhui Medical University, Hefei, China.
Pokaż więcej
Źródło:
Open forum infectious diseases [Open Forum Infect Dis] 2016 Aug 30; Vol. 3 (4), pp. ofw175. Date of Electronic Publication: 2016 Aug 30 (Print Publication: 2016).
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Development of Neutralization Assay Using an eGFP Chikungunya Virus.
Autorzy:
Deng CL; Key Laboratory of Special Pathogens and Biosafety, Center for Emerging Infectious Diseases, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China. .
Liu SQ; Key Laboratory of Special Pathogens and Biosafety, Center for Emerging Infectious Diseases, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China. luckyliu_.
Zhou DG; Ningbo International Travel Healthcare Center, Ningbo 315012, China. .
Xu LL; Key Laboratory of Special Pathogens and Biosafety, Center for Emerging Infectious Diseases, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China. .
Li XD; School of Medicine, Hunan Normal University, Changsha 410000, China. .
Zhang PT; Key Laboratory of Special Pathogens and Biosafety, Center for Emerging Infectious Diseases, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China. .
Li PH; Key Laboratory of Special Pathogens and Biosafety, Center for Emerging Infectious Diseases, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China. .
Ye HQ; Key Laboratory of Special Pathogens and Biosafety, Center for Emerging Infectious Diseases, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China. .
Wei HP; Key Laboratory of Special Pathogens and Biosafety, Center for Emerging Infectious Diseases, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China. .
Yuan ZM; Key Laboratory of Special Pathogens and Biosafety, Center for Emerging Infectious Diseases, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China. .
Qin CF; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China. chengfeng_qin@126.com.
Zhang B; Key Laboratory of Special Pathogens and Biosafety, Center for Emerging Infectious Diseases, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China. .
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Źródło:
Viruses [Viruses] 2016 Jun 28; Vol. 8 (7). Date of Electronic Publication: 2016 Jun 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Genes, Reporter*
Antibodies, Neutralizing/*immunology
Antibodies, Viral/*immunology
Chikungunya virus/*immunology
Green Fluorescent Proteins/*analysis
Neutralization Tests/*methods
Staining and Labeling/*methods
Animals ; Cell Line ; Chikungunya virus/genetics ; Chikungunya virus/physiology ; Green Fluorescent Proteins/genetics ; Mass Screening/methods ; Recombinant Proteins/analysis ; Recombinant Proteins/genetics ; Virus Replication
Czasopismo naukowe
Tytuł:
Epidemiological and Virological Characterizations of the 2014 Dengue Outbreak in Guangzhou, China.
Autorzy:
Zhao H; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
Zhang FC; Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, China.
Zhu Q; Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, China.
Wang J; Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, China.
Hong WX; Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, China.
Zhao LZ; Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, China.
Deng YQ; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
Qiu S; Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, China.
Zhang Y; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
Cai WP; Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, China.
Cao WC; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
Qin CF; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China.
Pokaż więcej
Źródło:
PloS one [PLoS One] 2016 Jun 03; Vol. 11 (6), pp. e0156548. Date of Electronic Publication: 2016 Jun 03 (Print Publication: 2016).
Typ publikacji:
Journal Article
MeSH Terms:
Dengue/*epidemiology
Adult ; Aged ; Aged, 80 and over ; China/epidemiology ; Dengue Virus/classification ; Dengue Virus/genetics ; Dengue Virus/pathogenicity ; Disease Outbreaks/statistics & numerical data ; Female ; Genome, Viral/genetics ; Genotype ; Humans ; Male ; Middle Aged ; Molecular Epidemiology ; Phylogeny ; Sequence Analysis, DNA ; Serogroup
Czasopismo naukowe
Tytuł:
Dengue Specific Immunoglobulin A Antibody is Present in Urine and Associated with Disease Severity.
Autorzy:
Zhao H; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, People's Republic of China.
Qiu S; Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou 510060, People's Republic of China.
Hong WX; Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou 510060, People's Republic of China.
Song KY; Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou 510060, People's Republic of China.
Wang J; Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou 510060, People's Republic of China.
Yang HQ; Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou 510060, People's Republic of China.
Deng YQ; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, People's Republic of China.
Zhu SY; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, People's Republic of China.
Zhang FC; Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou 510060, People's Republic of China.
Qin CF; Department of Virology, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, People's Republic of China.
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2016 Jun 02; Vol. 6, pp. 27298. Date of Electronic Publication: 2016 Jun 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antibodies, Viral/*urine
Dengue/*immunology
Dengue/*pathology
Dengue Virus/*immunology
Immunoglobulin A/*urine
Adult ; Aged ; Aged, 80 and over ; China ; Female ; Humans ; Male ; Middle Aged ; Young Adult
Czasopismo naukowe

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