Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""Quantitative Trait Loci genetics"" wg kryterium: Temat


Tytuł :
Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data
Autorzy :
Haworth, Simon
Divaris, Kimon
Kamatani, Yoichiro
Teumer, Alexander
Sakaue, Saori
Yu, Yau-Hua
Magnusson, Patrik K. E.
Okada, Yukinori
Völker, Uwe
Kocher, Thomas
Laitala, Marja-Liisa
Sofer, Tamar
Shaffer, John R.
Timpson, Nicholas J.
Shungin, Dmitry
Agler, Cary S.
Keun Lee, Myoung
Grinde, Kelsey
Hindy, George
Alaraudanjoki, Viivi
Pesonen, Paula
Holtfreter, Birte
Hirata, Jun
Ridker, Paul M.
Giulianini, Franco
Chasman, Daniel I.
Sudo, Takeaki
Anttonen, Vuokko
Orho-Melander, Marju
Vieira, Alexandre
Marazita, Mary L.
Kubo, Michiaki
Furuichi, Yasushi
North, Kari E.
Offenbacher, Steve
Ingelsson, Erik
Franks, Paul W.
Johansson, Ingegerd
Pokaż więcej
Temat :
Dentistry
Quantitative Trait Loci/genetics
Mendelian Randomization Analysis
Research Support, Non-U.S. Gov't
Epidemiology
Polymorphism, Single Nucleotide
Genomics
Self Report/statistics & numerical data
Periodontitis/epidemiology
Dental Caries/epidemiology
Meta-Analysis
Heredity
Article
Odontologi
Oral diseases
Medical genetics
Genome-Wide Association Study
Science
Journal Article
Genetic Predisposition to Disease
stomatognathic diseases
Humans
Genome-wide association studies
Źródło :
Shungin, D, Haworth, S, Divaris, K, Agler, C, Kamatani, Y, Lee, M K, Grinde, K, Hindy, G, Viivi Alaraudanjoki, V, Pesonen, P, Teumer, A, Holtfreter, B, Sakaue, S, Hirata, J, Yu, Y-H, Ridker, P, Giulianini, F, Chasman, D I, Magnusson, P K E, Sudo, T, Okada, Y, Völker, U, Kocher, T, Anttonen, V, Laitala, M-L, Orho-Melander, M, Sofer, T, Shaffer, J R, Vieira, A, Marazita, M L, Kubo, M, Furuichi, Y, North, K, Offenbacher, S, Ingelsson, E, Franks, P W, Timpson, N & Johansson, I 2019, ' Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data ', Nature Communications, vol. 10, 2773 . https://doi.org/10.1038/s41467-019-10630-1
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Opis pliku :
application/pdf
Tytuł :
Gene expression imputation across multiple brain regions provides insights into schizophrenia risk
Autorzy :
Huckins, Laura M
Dobbyn, Amanda
Ruderfer, Douglas M
Hoffman, Gabriel
Wang, Weiqing
Pardiñas, Antonio F
Rajagopal, Veera M
Als, Thomas D
T Nguyen, Hoang
Girdhar, Kiran
Boocock, James
Roussos, Panos
Fromer, Menachem
Kramer, Robin
Domenici, Enrico
Gamazon, Eric R
Purcell, Shaun
Demontis, Ditte
Børglum, Anders D
Walters, James T R
O'Donovan, Michael C
Sullivan, Patrick
Owen, Michael J
Devlin, Bernie
Sieberts, Solveig K
Cox, Nancy J
Im, Hae Kyung
Sklar, Pamela
Stahl, Eli A
Mortensen, Preben Bo
Pokaż więcej
Temat :
TRAITS
CHILDHOOD
TRANSCRIPTOME
Quantitative Trait Loci/genetics
ASSOCIATION
VARIANTS
Genome-Wide Association Study/methods
PSYCHOSIS
Genotype
Brain/physiopathology
MOUSE
COGNITIVE DEFICITS
DISORDER
Transcriptome/genetics
Schizophrenia/genetics
ACUTE INTERMITTENT PORPHYRIA
Risk
Genetic Predisposition to Disease
Humans
Human medicine
Case-Control Studies
Gene Expression/genetics
Polymorphism, Single Nucleotide/genetics
Źródło :
Huckins, L M, Dobbyn, A, Ruderfer, D M, Hoffman, G, Wang, W, Pardiñas, A F, Rajagopal, V M, Als, T D, T Nguyen, H, Girdhar, K, Boocock, J, Roussos, P, Fromer, M, Kramer, R, Domenici, E, Gamazon, E R, Purcell, S, Demontis, D, Børglum, A D, Walters, J T R, O'Donovan, M C, Sullivan, P, Owen, M J, Devlin, B, Sieberts, S K, Cox, N J, Im, H K, Sklar, P, Stahl, E A, CommonMind Consortium, The Schizophrenia Working Group of the Psychiatric Genomics Consortium & iPSYCH-GEMS Schizophrenia Working Group 2019, ' Gene expression imputation across multiple brain regions provides insights into schizophrenia risk ', Nature Genetics, vol. 51, no. 4, pp. 659-674 . https://doi.org/10.1038/s41588-019-0364-4
Opis pliku :
text
Tytuł :
GARFIELD classifies disease-relevant genomic features through integration of functional annotations with association signals
Autorzy :
Iotchkova, Valentina
Ritchie, Graham R.S.
Geihs, Matthias
Morganella, Sandro
Min, Josine L.
Walter, Klaudia
Timpson, Nicholas John
Dunham, Ian
Birney, Ewan
Soranzo, Nicole
Pokaż więcej
Temat :
Phenotype
Software
Disease/genetics
Quantitative Trait Loci/genetics
Genome-Wide Association Study/methods
Article
Research Support, Non-U.S. Gov't
Genomics/methods
Regulatory Sequences, Nucleic Acid/genetics
ICEP
Journal Article
Genome/genetics
Humans
Molecular Sequence Annotation/methods
Polymorphism, Single Nucleotide/genetics
Źródło :
Lotchkova, V, Ritchie, G R S, Geihs, M, Morganella, S, Min, J, Walter, K, Timpson, N, Dunham, I, Birney, E, Soranzo, N 2019, ' GARFIELD classifies disease-relevant genomic features through integration of functional annotations with association signals ', Nature Genetics, vol. 51, no. 2, pp. 343-353 . https://doi.org/10.1038/s41588-018-0322-6
Opis pliku :
application/pdf
Tytuł :
Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies
Autorzy :
Hjalgrim, Helle
Møller, Rikke S.
Pokaż więcej
Temat :
Case-Control Studies
Chromosome Mapping
Epilepsy/classification
Gene Expression Regulation
Gene Frequency
Genetic Predisposition to Disease/genetics
Genome-Wide Association Study/methods
Genotype
Humans
Linkage Disequilibrium
Polymorphism, Single Nucleotide
Quantitative Trait Loci/genetics
Źródło :
Hjalgrim, H, Møller, R S & The International League Against Epilepsy Consortium on Complex Epilepsies 2018, ' Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies ', Nature Communications, vol. 9, 5269 . https://doi.org/10.1038/s41467-018-07524-z
Opis pliku :
application/pdf
Tytuł :
Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk
Autorzy :
Bossé, Yohan
Wu, Xifeng
Bojesen, Stig E.
Rennert, Gad
Schabath, Matthew B.
Bertazzi, Pier A.
Pesatori, Angela C.
Fernandez-Somoano, Ana
van der Heijden, Erik H. F. M.
Kim, Jin Hee
Muller, David C.
Cox, Angela
Risch, Angela
Grankvist, Kjell
Arnold, Susanne M.
Houlston, Richard
Obeidat, Ma’en
Timens, Wim
Tobin, Martin D.
Brennan, Paul
Amos, Christopher I.
Ji, Xuemei
Landi, Maria Teresa
Gui, Jiang
Xiao, Xiangjun
Qian, David
Joubert, Philippe
Lamontagne, Maxime
Li, Yafang
Gorlov, Ivan
de Biasi, Mariella
Han, Younghun
Gorlova, Olga
Hung, Rayjean J.
McKay, James
Zong, Xuchen
Carreras-Torres, Robert
Christiani, David C.
Caporaso, Neil
Johansson, Mattias
Liu, Geoffrey
Le Marchand, Loic
Albanes, Demetrios
Bickeböller, Heike
Aldrich, Melinda C.
Bush, William S.
Tardon, Adonina
Chen, Chu
Teare, M. Dawn
Field, John K.
Kiemeney, Lambertus A.
Lazarus, Philip
Haugen, Aage
Lam, Stephen
Andrew, Angeline S.
Shen, Hongbing
Hong, Yun-Chul
Yuan, Jian-Min
Ye, Yuanqing
Diao, Nancy
Su, Li
Zhang, Ruyang
Brhane, Yonathan
Leighl, Natasha
Johansen, Jakob S.
Mellemgaard, Anders
Saliba, Walid
Haiman, Christopher
Wilkens, Lynne
Fernandez-Tardon, Guillermo
Dai, Juncheng
Hu, Zhibin
Davies, Michael P. A.
Marcus, Michael W.
Brunnström, Hans
Manjer, Jonas
Melander, Olle
Overvad, Kim
Trichopoulou, Antonia
Tumino, Rosario
Doherty, Jennifer
Goodman, Gary E.
Taylor, Fiona
Woll, Penella
Brüske, Irene
Manz, Judith
Muley, Thomas
Rosenberger, Albert
Johansson, Mikael
Shepherd, Frances
Tsao, Ming-Sound
Haura, Eric B.
Bolca, Ciprian
Holcatova, Ivana
Janout, Vladimir
Kontic, Milica
Lissowska, Jolanta
Mukeria, Anush
Ognjanovic, Simona
Orlowski, Tadeusz M.
Scelo, Ghislaine
Swiatkowska, Beata
Zaridze, David
Bakke, Per
Skaug, Vidar
Zienolddiny, Shanbeh
Duell, Eric J.
Butler, Lesley M.
Koh, Woon-Puay
Gao, Yu-Tang
McLaughlin, John
Stevens, Victoria
Nickle, David C.
Zhu, Bin
Song, Lei
Artigas, María Soler
Wain, Louise V.
Gu, Fangyi
Byun, Jinyoung
Kamal, Ahsan
Zhu, Dakai
Tyndale, Rachel F.
Wei, Wei-Qi
Chanock, Stephen
Pokaż więcej
Temat :
Lung Neoplasms
Infant, Newborn
Young Adult
AFRICAN-AMERICANS
Infant
Research Support, Non-U.S. Gov't
Gene Ontology
Gene Regulatory Networks
Polymorphism, Single Nucleotide
CA2+ TRANSPORT
Science & Technology - Other Topics
LOCI
Female
Lung Neoplasms/genetics
Risk Factors
MD Multidisciplinary
Chromosomes, Human, Pair 15
Article
Medical Genetics
Science & Technology
Medicinsk genetik
Science
Cohort Studies
Adolescent
Adult
Male
Child
Quantitative Trait Loci/genetics
Multidisciplinary Sciences
Quantitative Trait Loci
Smoking
Child, Preschool
NICOTINE DEPENDENCE
EXPRESSION
Aged
SET ENRICHMENT ANALYSIS
ADENOCARCINOMA
Middle Aged
Humans
Reproducibility of Results
Genetic Predisposition to Disease
Chemistry (all)
Biochemistry, Genetics and Molecular Biology (all)
Physics and Astronomy (all)
Research Support, N.I.H., Extramural
Chromosomes, Human, Pair 15/genetics
Journal Article
GENOME-WIDE ASSOCIATION
Smoking/adverse effects
GENETIC-VARIANTS
Settore MED/44 - Medicina del Lavoro
Źródło :
Ji, X, Bossé, Y, Landi, M T, Gui, J, Xiao, X, Qian, D, Joubert, P, Lamontagne, M, Li, Y, Gorlov, I, de Biasi, M, Han, Y, Gorlova, O, Hung, R J, Wu, X, McKay, J, Zong, X, Carreras-Torres, R, Christiani, D C, Caporaso, N, Johansson, M, Liu, G, Bojesen, S E, Le Marchand, L, Albanes, D, Bickeböller, H, Aldrich, M C, Bush, W S, Tardon, A, Rennert, G, Chen, C, Teare, M D, Field, J K, Kiemeney, L A, Lazarus, P, Haugen, A, Lam, S, Schabath, M B, Andrew, A S, Shen, H, Hong, Y-C, Yuan, J-M, Bertazzi, P A, Pesatori, A C, Ye, Y, Diao, N, Su, L, Zhang, R, Brhane, Y, Leighl, N, Johansen, J S, Mellemgaard, A, Saliba, W, Haiman, C, Wilkens, L, Fernandez-Somoano, A, Fernandez-Tardon, G, van der Heijden, E H F M, Kim, J H, Dai, J, Hu, Z, Davies, M P A, Marcus, M W, Brunnström, H, Manjer, J, Melander, O, Muller, D C, Overvad, K, Trichopoulou, A, Tumino, R, Doherty, J, Goodman, G E, Cox, A, Taylor, F, Woll, P, Brüske, I, Manz, J, Muley, T, Risch, A, Rosenberger, A, Grankvist, K, Johansson, M, Shepherd, F, Tsao, M-S, Arnold, S M, Haura, E B, Bolca, C, Holcatova, I, Janout, V, Kontic, M, Lissowska, J, Mukeria, A, Ognjanovic, S, Orlowski, T M, Scelo, G, Swiatkowska, B, Zaridze, D, Bakke, P, Skaug, V, Zienolddiny, S, Duell, E J, Butler, L M, Koh, W-P, Gao, Y-T, Houlston, R, McLaughlin, J, Stevens, V, Nickle, D C, Obeidat, M, Timens, W, Zhu, B, Song, L, Artigas, M S, Tobin, M D, Wain, L V, Gu, F, Byun, J, Kamal, A, Zhu, D, Tyndale, R F, Wei, W-Q, Chanock, S, Brennan, P & Amos, C I 2018, ' Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk ', Nature Communications, vol. 9, no. 1, pp. 3221 . https://doi.org/10.1038/s41467-018-05074-y
Ji, X, Bossé, Y, Landi, M T, Gui, J, Xiao, X, Qian, D, Joubert, P, Lamontagne, M, Li, Y, Gorlov, I, de Biasi, M, Han, Y, Gorlova, O, Hung, R J, Wu, X, McKay, J, Zong, X, Carreras-Torres, R, Christiani, D C, Caporaso, N, Johansson, M, Liu, G, Bojesen, S E, Le Marchand, L, Albanes, D, Bickeböller, H, Aldrich, M C, Bush, W S, Tardon, A, Rennert, G, Chen, C, Teare, M D, Field, J K, Kiemeney, L A, Lazarus, P, Haugen, A, Lam, S, Schabath, M B, Andrew, A S, Shen, H, Hong, Y-C, Yuan, J-M, Bertazzi, P A, Pesatori, A C, Ye, Y, Diao, N, Su, L, Zhang, R, Brhane, Y, Leighl, N, Johansen, J S, Mellemgaard, A, Saliba, W, Haiman, C, Wilkens, L, Fernandez-Somoano, A, Fernandez-Tardon, G, van der Heijden, E H F M, Kim, J H, Dai, J, Hu, Z, Davies, M P A, Marcus, M W, Brunnström, H, Manjer, J, Melander, O, Muller, D C, Overvad, K, Trichopoulou, A, Tumino, R, Doherty, J, Goodman, G E, Cox, A, Taylor, F, Woll, P, Brüske, I, Manz, J, Muley, T, Risch, A, Rosenberger, A, Grankvist, K, Johansson, M, Shepherd, F, Tsao, M-S, Arnold, S M, Haura, E B, Bolca, C, Holcatova, I, Janout, V, Kontic, M, Lissowska, J, Mukeria, A, Ognjanovic, S, Orlowski, T M, Scelo, G, Swiatkowska, B, Zaridze, D, Bakke, P, Skaug, V, Zienolddiny, S, Duell, E J, Butler, L M, Koh, W-P, Gao, Y-T, Houlston, R, McLaughlin, J, Stevens, V, Nickle, D C, Obeidat, M, Timens, W, Zhu, B, Song, L, Artigas, M S, Tobin, M D, Wain, L V, Gu, F, Byun, J, Kamal, A, Zhu, D, Tyndale, R F, Wei, W-Q, Chanock, S, Brennan, P & Amos, C I 2018, ' Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk ', Nature Communications, vol. 9, 3221 . https://doi.org/10.1038/s41467-018-05074-y
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Opis pliku :
application/pdf; application/vnd.openxmlformats-officedocument.wordprocessingml.document
Tytuł :
Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility.
Autorzy :
Dennis, Joe
Bruinsma, Fiona
Cunningham, Julie M.
Giles, Graham G.
Jakubowska, Anna
Li, Zheng
Sellers, Thomas A.
Pharoah, Paul D. P.
Goode, Ellen L.
Earp, Madalene
Tyrer, Jonathan P.
Winham, Stacey J.
Lin, Hui-Yi
Chornokur, Ganna
Aben, Katja K. H.
Anton‐Culver, Hoda
Antonenkova, Natalia
Bandera, Elisa V.
Bean, Yukie T.
Beckmann, Matthias W.
Bjorge, Line
Bogdanova, Natalia
Brinton, Louise A.
Brooks-Wilson, Angela
Bunker, Clareann H.
Butzow, Ralf
Campbell, Ian G.
Carty, Karen
Chang-Claude, Jenny
Cook, Linda S.
Cramer, Daniel W
Cybulski, Cezary
Dansonka-Mieszkowska, Agnieszka
Despierre, Evelyn
Doherty, Jennifer A.
Dörk, Thilo
du Bois, Andreas
Dürst, Matthias
Easton, Douglas F.
Eccles, Diana M.
Edwards, Robert P.
Ekici, Arif B.
Fasching, Peter A.
Fridley, Brooke L.
Gentry-Maharaj, Aleksandra
Glasspool, Rosalind
Goodman, Marc T.
Gronwald, Jacek
Harter, Philipp
Hein, Alexander
Heitz, Florian
Hildebrandt, Michelle A. T.
Hillemanns, Peter
Hogdall, Claus K.
Høgdall, Estrid
Hosono, Satoyo
Iversen, Edwin S.
Jensen, Allan
Ji, Bu-Tian
Jung, Audrey Y.
Karlan, Beth Y.
Kellar, Melissa
Kiemeney, Lambertus A.
Kiong Lim, Boon
Kjaer, Susanne K.
Krakstad, Camilla
Kupryjanczyk, Jolanta
Lambrechts, Diether
Lambrechts, Sandrina
Le, Nhu D.
Lele, Shashi
Lester, Jenny
Levine, Douglas A.
Liang, Dong
Lissowska, Jolanta
Lu, Karen
Lubinski, Jan
Lundvall, Lene
Massuger, Leon F. A. G.
Matsuo, Keitaro
McGuire, Valerie
McLaughlin, John R.
McNeish, Iain
Menon, Usha
Milne, Roger L.
Modugno, Francesmary
Moysich, Kirsten B.
Ness, Roberta B.
Nevanlinna, Heli
Odunsi, Kunle
Olson, Sara H.
Orlow, Irene
Orsulic, Sandra
Paul, James
Pejovic, Tanja
Pelttari, Liisa M.
Permuth, Jenny B.
Pike, Malcolm C.
Poole, Elizabeth M.
Rosen, Barry
Rossing, Mary Anne
Rothstein, Joseph H.
Runnebaum, Ingo B.
Rzepecka, Iwona K.
Schernhammer, Eva
Schwaab, Ira
Shu, Xiao-Ou
Shvetsov, Yurii B.
Siddiqui, Nadeem
Sieh, Weiva
Song, Honglin
Southey, Melissa C.
Spiewankiewicz, Beata
Sucheston-Campbell, Lara
Tangen, Ingvild L.
Teo, Soo-Hwang
Terry, Kathryn L.
Thompson, Pamela J.
Thomsen, Lotte
Tworoger, Shelley S.
van Altena, Anne M.
Vergote, Ignace
Vestrheim Thomsen, Liv Cecilie
Vierkant, Robert A.
Walsh, Christine S.
Wang-Gohrke, Shan
Wentzensen, Nicolas
Whittemore, Alice S.
Wicklund, Kristine G.
Wilkens, Lynne R.
Woo, Yin-Ling
Wu, Anna H.
Wu, Xifeng
Xiang, Yong-Bing
Yang, Hannah
Zheng, Wei
Ziogas, Argyrios
Lee, Alice W
Pearce, Celeste L.
Berchuck, Andrew
Schildkraut, Joellen M.
Ramus, Susan J.
Monteiro, Alvaro N. A.
Narod, Steven A.
Gayther, Simon A.
Kelemen, Linda E.
Chenevix-Trench, Georgia
Risch, Harvey A.
Phelan, Catherine M.
Pokaż więcej
Temat :
Cell Membranes
Human Genetics
Oncology
Research Support, Non-U.S. Gov't
endocrine system diseases
Signaling Molecules
Histology
Genome Analysis
Polymorphism, Single Nucleotide
Research Support, N.I.H., Intramural
Science & Technology - Other Topics
Female
Guanosine Triphosphatase
3122 Cancers
Risk Factors
MD Multidisciplinary
Biology and Life Sciences
Signal Transduction
Monomeric GTP-Binding Proteins/genetics
Guanine Nucleotide Exchange Factors
Enzymology
Genotype
Rho Guanine Nucleotide Exchange Factors
Ras Signaling
Science & Technology
Gene Regulation
Science
Research Support, U.S. Gov't, Non-P.H.S
Gene Expression
SUPER-ENHANCERS
Polymorphism, Single Nucleotide/genetics
Carcinoma, Ovarian Epithelial
Computational Biology
Research Article
TRAITS
3123 Gynaecology and paediatrics
Anatomy
Carcinoma, Ovarian Epithelial/genetics
Enzymes
Quantitative Trait Loci/genetics
Multidisciplinary Sciences
Quantitative Trait Loci
Research Support, U.S. Gov't, P.H.S
Membrane Proteins
Genetics
3111 Biomedicine
Invasive Tumors
Proteins
A Kinase Anchor Proteins/genetics
Genomics
Cancers and Neoplasms
Hydrolases
Medicine
Monomeric GTP-Binding Proteins
Cell Biology
Research Support, N.I.H., Extramural
Cellular Structures and Organelles
CARCINOMA
Biochemistry
Cell Signaling
General Science & Technology
Genetic Association Studies
Journal Article
Medicine and Health Sciences
Genetic Predisposition to Disease
GENOME-WIDE ASSOCIATION
A Kinase Anchor Proteins
Genome-Wide Association Studies
Humans
Rho Guanine Nucleotide Exchange Factors/genetics
Źródło :
Earp, M, Tyrer, J P, Winham, S J, Lin, H-Y, Chornokur, G, Dennis, J, Aben, K K H, Anton-Culver, H, Antonenkova, N, Bandera, E V, Bean, Y T, Beckmann, M W, Bjorge, L, Bogdanova, N, Brinton, L A, Brooks-Wilson, A, Bruinsma, F, Bunker, C H, Butzow, R, Campbell, I G, Carty, K, Chang-Claude, J, Cook, L S, Cramer, D W, Cunningham, J M, Cybulski, C, Dansonka-Mieszkowska, A, Despierre, E, Doherty, J A, Dörk, T, du Bois, A, Dürst, M, Easton, D F, Eccles, D M, Edwards, R P, Ekici, A B, Fasching, P A, Fridley, B L, Gentry-Maharaj, A, Giles, G G, Glasspool, R, Goodman, M T, Gronwald, J, Harter, P, Hein, A, Heitz, F, Hildebrandt, M A T, Hillemanns, P, Hogdall, C K, Høgdall, E, Hosono, S, Iversen, E S, Jakubowska, A, Jensen, A, Ji, B-T, Jung, A Y, Karlan, B Y, Kellar, M, Kiemeney, L A, Kiong Lim, B, Kjaer, S K, Krakstad, C, Kupryjanczyk, J, Lambrechts, D, Lambrechts, S, Le, N D, Lele, S, Lester, J, Levine, D A, Li, Z, Liang, D, Lissowska, J, Lu, K, Lubinski, J, Lundvall, L, Massuger, L F A G, Matsuo, K, McGuire, V, McLaughlin, J R, McNeish, I, Menon, U, Milne, R L, Modugno, F, Moysich, K B, Ness, R B, Nevanlinna, H, Odunsi, K, Olson, S H, Orlow, I, Orsulic, S, Paul, J, Pejovic, T, Pelttari, L M, Permuth, J B, Pike, M C, Poole, E M, Rosen, B, Rossing, M A, Rothstein, J H, Runnebaum, I B, Rzepecka, I K, Schernhammer, E, Schwaab, I, Shu, X-O, Shvetsov, Y B, Siddiqui, N, Sieh, W, Song, H, Southey, M C, Spiewankiewicz, B, Sucheston-Campbell, L, Tangen, I L, Teo, S-H, Terry, K L, Thompson, P J, Thomsen, L, Tworoger, S S, van Altena, A M, Vergote, I, Vestrheim Thomsen, L C, Vierkant, R A, Walsh, C S, Wang-Gohrke, S, Wentzensen, N, Whittemore, A S, Wicklund, K G, Wilkens, L R, Woo, Y-L, Wu, A H, Wu, X, Xiang, Y-B, Yang, H, Zheng, W, Ziogas, A, Lee, A W, Pearce, C L, Berchuck, A, Schildkraut, J M, Ramus, S J, Monteiro, A N A, Narod, S A, Sellers, T A, Gayther, S A, Kelemen, L E, Chenevix-Trench, G, Risch, H A, Pharoah, P D P, Goode, E L & Phelan, C M 2018, ' Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility ', PLoS ONE, vol. 13, no. 7, e0197561 . https://doi.org/10.1371/journal.pone.0197561
PLoS ONE, Vol 13, Iss 7, p e0197561 (2018)
Opis pliku :
application/pdf; Electronic-eCollection; text
Tytuł :
Multiethnic Meta-Analysis Identifies RAI1 as a Possible Obstructive Sleep Apnea-related Quantitative Trait Locus in Men.
Autorzy :
Chen, Han
Cade, Brian E.
Gleason, Kevin J.
Bjonnes, Andrew C.
Stilp, Adrienne M.
Sofer, Tamar
Conomos, Matthew P.
Ancoli-Israel, Sonia
Arens, Raanan
Azarbarzin, Ali
Bell, Graeme I.
Below, Jennifer E.
Chun, Sung
Evans, Daniel S.
Ewert, Ralf
Frazier-Wood, Alexis C.
Gharib, Sina A.
Haba-Rubio, José
Hagen, Erika W.
Heinzer, Raphael
Hillman, David R.
Johnson, W. Craig
Kutalik, Zoltan
Lane, Jacqueline M.
Larkin, Emma K.
Lee, Seung Ku
Liang, Jingjing
Loredo, Jose S.
Mukherjee, Sutapa
Palmer, Lyle J.
Papanicolaou, George J.
Penzel, Thomas
Peppard, Paul E.
Post, Wendy S.
Ramos, Alberto R.
Rice, Ken
Rotter, Jerome I.
Sands, Scott A.
Shah, Neomi A.
Shin, Chol
Stone, Katie L.
Stubbe, Beate
Sul, Jae Hoon
Tafti, Mehdi
Taylor, Kent D.
Teumer, Alexander
Thornton, Timothy A.
Tranah, Gregory J.
Wang, Chaolong
Wang, Heming
Warby, Simon C.
Wellman, D. Andrew
Zee, Phyllis C.
Hanis, Craig L.
Laurie, Cathy C.
Gottlieb, Daniel J.
Patel, Sanjay R.
Zhu, Xiaofeng
Sunyaev, Shamil R.
Saxena, Richa
Lin, Xihong
Redline, Susan
Pokaż więcej
Temat :
nervous system diseases
respiratory tract diseases
Adult
Aged
Female
Genome-Wide Association Study
Humans
Male
Middle Aged
Phosphatidylethanolamine N-Methyltransferase/genetics
Quantitative Trait Loci/genetics
Sex Characteristics
Sleep Apnea, Obstructive/genetics
Sleep, REM/physiology
Sterol Regulatory Element Binding Protein 1/genetics
Transcription Factors/genetics
ras Proteins/genetics
genetics
genome-wide association studies
multiethnic
obstructive sleep apnea
sexual dimorphism
Original Research
Źródło :
American journal of respiratory cell and molecular biology, vol. 58, no. 3, pp. 391-401
Opis pliku :
application/pdf
Tytuł :
Bivariate genome-wide association analysis implicates pleiotropic effects at the SREBF1/TOM1L2 locus on bone mineral density and lean mass in children
Autorzy :
Medina-Gomez, Carolina
Kemp, John P.
Boer, Cindy G.
Ahluwalia, Tarunveer S.
Rivadeneira, Fernando
Dimou, Niki L.
Kreiner, Eskil
Chesi, Alessandra
Zemel, Babette S.
Bønnelykke, Klaus
Bisgaard, Hans
Evangelou, Evangelos
Heppe, Denise H. M.
Bonewald, Lynda F.
Gorski, Jeffrey P.
Ghanbari, Mohsen
Demissie, Serkalem
Duque, Gustavo
Maurano, Matthew T.
Kiel, Douglas P.
Hsu, Yi-Hsiang
C.J. van der Eerden, Bram
Ackert-Bicknell, Cheryl
Reppe, Sjur
Gautvik, Kaare M.
Raastad, Truls
Karasik, David
van de Peppel, Jeroen
Jaddoe, Vincent W. V.
Uitterlinden, André G.
Tobias, Jonathan H.
Grant, Struan F.A.
Bagos, Pantelis G.
Evans, David M.
Pokaż więcej
Temat :
MD Multidisciplinary
Bone Density
Meta-Analysis as Topic
Quantitative Trait Loci/genetics
Musculoskeletal Development/genetics
Genome-Wide Association Study/methods
Multivariate Analysis
Research Support, Non-U.S. Gov't
Article
Body Weight
Genetic Pleiotropy
Research Support, N.I.H., Extramural
Sterol Regulatory Element Binding Protein 1/genetics
Polymorphism, Single Nucleotide
Journal Article
Carrier Proteins/genetics
Female
Humans
Gene Expression
Male
Child
Źródło :
Medina-Gomez, C, Kemp, J P, Dimou, N L, Kreiner, E, Chesi, A, Zemel, B S, Bønnelykke, K, Boer, C G, Ahluwalia, T S, Bisgaard, H, Evangelou, E, Heppe, D H M, Bonewald, L F, Gorski, J P, Ghanbari, M, Demissie, S, Duque, G, Maurano, M T, Kiel, D P, Hsu, Y-H, C J van der Eerden, B, Ackert-Bicknell, C, Reppe, S, Gautvik, K M, Raastad, T, Karasik, D, van de Peppel, J, Jaddoe, V W V, Uitterlinden, A G, Tobias, J H, Grant, S F A, Bagos, P G, Evans, D M & Rivadeneira, F 2017, ' Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus ', Nature Communications, vol. 8, 121 . https://doi.org/10.1038/s41467-017-00108-3
Nature Communications, 8(1)
Medina-Gomez, C, Kemp, J, Dimou, N L, Kreiner-Moller, E, Chesi, A, Zemel, B S, Bønnelykke, K, Boer, C G, Ahluwalia, T S, Bisgaard, H, Evangelou, E, Heppe, D H M, Bonewald, LF, Gorski, J P, Ghanbari, M, Demissie, S, Duque, G, Maurano, M T, Kiel, D P, Evans, D, Tobias, J & Rivadeneira, F 2017, ' Bivariate genome-wide association analysis implicates pleiotropic effects at the SREBF1/TOM1L2 locus on bone mineral density and lean mass in children ', Nature Communications, vol. 8, 121 . https://doi.org/10.1038/s41467-017-00108-3
Opis pliku :
application/pdf
Tytuł :
quantiNemo: an individual-based program to simulate quantitative traits with explicit genetic architecture in a dynamic metapopulation
Autorzy :
Neuenschwander, S.
Hospital, F.
Guillaume, F.
Goudet, J.
Pokaż więcej
Temat :
Algorithms
Animals
Chromosome Mapping/methods
Computer Simulation
Genetics, Population
Humans
Models, Genetic
Quantitative Trait Loci/genetics
Quantitative Trait, Heritable
Software
Źródło :
Bioinformatics, vol. 24, no. 13, pp. 1552-1553
Opis pliku :
application/pdf
Tytuł :
Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease
Autorzy :
Webb, T. R.
Erdmann, J.
Stirrups, K. E.
Stitziel, N. O.
Masca, N. G. D.
Jansen, H.
Kanoni, S.
Nelson, C. P.
Ferrario, P. G.
Koenig, I. R.
Eicher, J. D.
Johnson, A. D.
Hamby, S. E.
Betsholtz, C.
Ruusalepp, A.
Franzen, O.
Schadt, E. E.
Bjoerkegren, J. L. M.
Weeke, P. E.
Auer, P. L.
Schick, U. M.
Lu, Y.
Zhang, H.
Dube, M-P
Goel, A.
Farrall, M.
Peloso, G. M.
Won, H-H
Do, R.
van Iperen, E.
Kruppa, J.
Mahajan, A.
Scott, R. A.
Willenborg, C.
Braund, P. S.
van Capelleveen, J. C.
Doney, A. S. F.
Donnelly, L. A.
Asselta, R.
Merlini, P. A.
Duga, S.
Marziliano, N.
Denny, J. C.
Shaffer, C.
El-Mokhtari, N. E.
Franke, A.
Heilmann, S.
Hengstenberg, C.
Hoffmann, P.
Holmen, O. L.
Hveem, K.
Jansson, J-H
Joeckel, K-H
Kessler, T.
Kriebel, J.
Laugwitz, K. L.
Marouli, E.
Martinelli, N.
McCarthy, M. I.
Van Zuydam, N. R.
Meisinger, C.
Esko, T.
Mihailov, E.
Escher, S. A.
Alver, M.
Moebus, S.
Morris, A. D.
Virtamo, J.
Nikpay, M.
Olivieri, O.
Provost, S.
AlQarawi, A.
Robertson, N. R.
Akinsansya, K. O.
Reilly, D. F.
Vogt, T. F.
Yin, W.
Asselbergs, F. W.
Kooperberg, C.
Jackson, R. D.
Stahl, E.
Mueller-Nurasyid, M.
Strauch, K.
Varga, T. V.
Waldenberger, M.
Zeng, L.
Chowdhury, R.
Salomaa, V.
Ford, I.
Jukema, J. W.
Amouyel, P.
Kontto, J.
Nordestgaard, B. G.
Ferrieres, J.
Saleheen, D.
Sattar, N.
Surendran, P.
Wagner, A.
Young, R.
Howson, J. M. M.
Butterworth, A. S.
Danesh, J.
Ardissino, D.
Bottinger, E. P.
Erbel, R.
Franks, P. W.
Girelli, D.
Hall, A. S.
Hovingh, G. K.
Kastrati, A.
Lieb, W.
Meitinger, T.
Kraus, W. E.
Shah, S. H.
McPherson, R.
Orho-Melander, M.
Melander, O.
Metspalu, A.
Palmer, C. N. A.
Peters, A.
Rader, D. J.
Reilly, M. P.
Loos, R. J. F.
Reiner, A. P.
Roden, D. M.
Tardif, J-C
Thompson, J. R.
Wareham, N. J.
Watkins, H.
Willer, C. J.
Samani, N. J.
Schunkert, H.
Deloukas, P.
Kathiresan, S.
Pokaż więcej
Temat :
Science & Technology, Life Sciences & Biomedicine, Cardiac & Cardiovascular Systems, Cardiovascular System & Cardiology, cholesteryl ester transfer protein, expression quantitative trait loci, genetics, genome-wide association, single nucleotide polymorphism, GENOME-WIDE ASSOCIATION, DENSITY-LIPOPROTEIN RECEPTOR, ABDOMINAL AORTIC-ANEURYSM, HEART-DISEASE, SCAVENGER RECEPTOR, PHOSPHOLIPASE A(2), COMMON VARIANTS, CETP MASS, SR-BI, RISK
Źródło :
Journal of the American College of Cardiology, 69 (7) pp. 823-836. (2017)
Opis pliku :
text
Tytuł :
Diversity and regulatory impact of copy number variation in the primate Macaca fascicularis
Autorzy :
Gschwind, Andreas R.
Singh, Anjali
Certa, Ulrich
Reymond, Alexandre
Heckel, Tobias
Pokaż więcej
Temat :
Biotechnology
Research Article
Cynomolgus monkey
Genetics
Animals
DNA Copy Number Variations
Gene Expression Profiling
Genotype
Macaca fascicularis/genetics
Quantitative Trait Loci/genetics
CNV
Gene expression
Olfactory receptors
eQTL
Źródło :
BMC genomics, vol. 18, no. 1, pp. 144
Opis pliku :
application/pdf

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies