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Wyszukujesz frazę ""Quercetin"" wg kryterium: Temat


Tytuł:
Anticancer Activity and Molecular Mechanisms of Acetylated and Methylated Quercetin in Human Breast Cancer Cells.
Autorzy:
Sakao K; The United Graduate School of Agriculture Sciences, Kagoshima University, Kagoshima 890-0065, Japan.; Graduate School of Agriculture, Forestry and Fisheries, Kagoshima University, Kagoshima 890-0065, Japan.
Hamamoto S; Graduate School of Agriculture, Forestry and Fisheries, Kagoshima University, Kagoshima 890-0065, Japan.
Urakawa D; The United Graduate School of Agriculture Sciences, Kagoshima University, Kagoshima 890-0065, Japan.
He Z; The United Graduate School of Agriculture Sciences, Kagoshima University, Kagoshima 890-0065, Japan.
Hou DX; The United Graduate School of Agriculture Sciences, Kagoshima University, Kagoshima 890-0065, Japan.; Graduate School of Agriculture, Forestry and Fisheries, Kagoshima University, Kagoshima 890-0065, Japan.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 May 20; Vol. 29 (10). Date of Electronic Publication: 2024 May 20.
Typ publikacji:
Journal Article
MeSH Terms:
Quercetin*/pharmacology
Quercetin*/analogs & derivatives
Quercetin*/chemistry
Breast Neoplasms*/metabolism
Breast Neoplasms*/drug therapy
Breast Neoplasms*/pathology
Apoptosis*/drug effects
Cell Proliferation*/drug effects
Humans ; Acetylation/drug effects ; Methylation ; Female ; MCF-7 Cells ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/chemistry ; Cell Line, Tumor ; Tumor Suppressor Protein p53/metabolism ; Caspase 3/metabolism
Czasopismo naukowe
Tytuł:
Surface modified niosomal quercetin with cationic lipid: an appropriate drug delivery system against Pseudomonas aeruginosa Infections.
Autorzy:
Hemmati J; Department of Microbiology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.; Student Research Committee, Hamadan University of Medical Sciences, Hamadan, Iran.
Chiani M; Department of NanoBiotechnology, Pasteur Institute of Iran, Tehran, Iran.
Chegini Z; Department of Microbiology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Seifalian A; Nanotechnology & Regenerative Medicine Commercialization Centre (NanoRegMed Ltd, Nanoloom Ltd & Liberum Health Ltd), LBIC, University of London, London, UK.
Arabestani MR; Department of Microbiology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran. .; Infectious Disease Research Center, Hamadan University of Medical Sciences, Hamadan, Iran. .
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Źródło:
Scientific reports [Sci Rep] 2024 Jun 11; Vol. 14 (1), pp. 13362. Date of Electronic Publication: 2024 Jun 11.
Typ publikacji:
Journal Article
MeSH Terms:
Pseudomonas aeruginosa*/drug effects
Liposomes*/chemistry
Quercetin*/pharmacology
Quercetin*/chemistry
Quercetin*/administration & dosage
Biofilms*/drug effects
Anti-Bacterial Agents*/pharmacology
Anti-Bacterial Agents*/chemistry
Anti-Bacterial Agents*/administration & dosage
Drug Delivery Systems*
Pseudomonas Infections*/drug therapy
Pseudomonas Infections*/microbiology
Microbial Sensitivity Tests*
Animals ; Mice ; Cations/chemistry ; Humans ; Lipids/chemistry ; Cell Line ; Amines
Czasopismo naukowe
Tytuł:
Accelerated full-thickness skin wound tissue regeneration by self-crosslinked chitosan hydrogel films reinforced by oxidized CNC-AgNPs stabilized Pickering emulsion for quercetin delivery.
Autorzy:
Sharma G; Department of Biomedical Science & Institute of Bioscience and Biotechnology, Kangwon National University, Chuncheon, 24341, Republic of Korea. .
George Joy J; Department of Biomedical Science & Institute of Bioscience and Biotechnology, Kangwon National University, Chuncheon, 24341, Republic of Korea.
Sharma AR; Institute for Skeletal Aging & Orthopedic Surgery, Hallym University-Chuncheon Sacred Heart Hospital, Chuncheon-si, 24252, Gangwon-do, Republic of Korea.
Kim JC; Department of Biomedical Science & Institute of Bioscience and Biotechnology, Kangwon National University, Chuncheon, 24341, Republic of Korea. .
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Źródło:
Journal of nanobiotechnology [J Nanobiotechnology] 2024 Jun 08; Vol. 22 (1), pp. 323. Date of Electronic Publication: 2024 Jun 08.
Typ publikacji:
Journal Article
MeSH Terms:
Quercetin*/chemistry
Quercetin*/pharmacology
Wound Healing*/drug effects
Chitosan*/chemistry
Emulsions*/chemistry
Skin*/drug effects
Skin*/injuries
Metal Nanoparticles*/chemistry
Silver*/chemistry
Hydrogels*/chemistry
Animals ; Mice ; Humans ; Biocompatible Materials/chemistry ; Bandages ; Drug Liberation ; Drug Delivery Systems/methods ; Cellulose/chemistry ; Male ; Regeneration/drug effects ; HaCaT Cells ; Oxidation-Reduction ; Methylgalactosides
Czasopismo naukowe
Tytuł:
Yishen Huatan Huoxue decoction and quercetin ameliorate decidualization dysfunction in polycystic ovary syndrome: A comprehensive investigation combining clinical trial and experimental studies.
Autorzy:
Wang J; Laboratory for Reproductive Immunology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.; The Academy of Integrative Medicine of Fudan University, Shanghai, China.; Shanghai Key Laboratory of Female Reproductive Endocrine-related Diseases, Shanghai, China.
Li L; Laboratory for Reproductive Immunology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.; The Academy of Integrative Medicine of Fudan University, Shanghai, China.; Shanghai Key Laboratory of Female Reproductive Endocrine-related Diseases, Shanghai, China.
Zhou J; Laboratory for Reproductive Immunology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.; The Academy of Integrative Medicine of Fudan University, Shanghai, China.; Shanghai Key Laboratory of Female Reproductive Endocrine-related Diseases, Shanghai, China.
Pan X; Laboratory for Reproductive Immunology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.; The Academy of Integrative Medicine of Fudan University, Shanghai, China.; Shanghai Key Laboratory of Female Reproductive Endocrine-related Diseases, Shanghai, China.
Qi Q; Laboratory for Reproductive Immunology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.; The Academy of Integrative Medicine of Fudan University, Shanghai, China.; Shanghai Key Laboratory of Female Reproductive Endocrine-related Diseases, Shanghai, China.
Sun H; Laboratory for Reproductive Immunology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.; The Academy of Integrative Medicine of Fudan University, Shanghai, China.; Shanghai Key Laboratory of Female Reproductive Endocrine-related Diseases, Shanghai, China.
Wang L; Laboratory for Reproductive Immunology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.; The Academy of Integrative Medicine of Fudan University, Shanghai, China.; Shanghai Key Laboratory of Female Reproductive Endocrine-related Diseases, Shanghai, China.
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Źródło:
Drug discoveries & therapeutics [Drug Discov Ther] 2024 Jun 06; Vol. 18 (2), pp. 117-129. Date of Electronic Publication: 2024 Apr 19.
Typ publikacji:
Journal Article
MeSH Terms:
Polycystic Ovary Syndrome*/drug therapy
Polycystic Ovary Syndrome*/metabolism
Quercetin*/pharmacology
Quercetin*/therapeutic use
Drugs, Chinese Herbal*/pharmacology
Drugs, Chinese Herbal*/therapeutic use
Female ; Animals ; Mice ; Humans ; Disease Models, Animal ; Glucose Transporter Type 4/metabolism ; Insulin Receptor Substrate Proteins/metabolism ; Signal Transduction/drug effects ; Adult ; Abortion, Spontaneous/drug therapy ; Insulin/blood ; Insulin/metabolism ; Dehydroepiandrosterone/pharmacology ; Decidua/drug effects ; Decidua/metabolism ; Estrous Cycle/drug effects ; Pregnancy
Czasopismo naukowe
Tytuł:
Therapeutic potential activity of quercetin complexes against Streptococcus pneumoniae.
Autorzy:
Osman ME; Botany and Microbiology Department, Faculty of Science, Helwan University, Ain Helwan, Cairo, 11795, Egypt.
Abo-Elnasr AA; Botany and Microbiology Department, Faculty of Science, Helwan University, Ain Helwan, Cairo, 11795, Egypt.
Mohamed ET; Botany and Microbiology Department, Faculty of Science, Helwan University, Ain Helwan, Cairo, 11795, Egypt. .
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Źródło:
Scientific reports [Sci Rep] 2024 Jun 05; Vol. 14 (1), pp. 12876. Date of Electronic Publication: 2024 Jun 05.
Typ publikacji:
Journal Article
MeSH Terms:
Streptococcus pneumoniae*/drug effects
Quercetin*/pharmacology
Quercetin*/chemistry
Anti-Bacterial Agents*/pharmacology
Anti-Bacterial Agents*/chemistry
Biofilms*/drug effects
Molecular Docking Simulation*
Microbial Sensitivity Tests*
Drug Synergism ; Bacterial Proteins/metabolism ; Bacterial Proteins/genetics ; Bacterial Proteins/chemistry ; Bacterial Proteins/antagonists & inhibitors ; Cysteine Endopeptidases/metabolism ; Cysteine Endopeptidases/chemistry ; Aminoacyltransferases/antagonists & inhibitors ; Aminoacyltransferases/metabolism ; Neuraminidase/antagonists & inhibitors ; Neuraminidase/metabolism
Czasopismo naukowe
Tytuł:
Chamaecyparis lawsoniana and Its Active Compound Quercetin as Ca Inhibitors in the Contraction of Airway Smooth Muscle.
Autorzy:
Flores-Soto E; Departamento de Farmacología, Facultad de Medicina, Universidad Nacional Autónoma de México, Avenida Universidad No. 3000, Alcaldía de Coyoacán, C.P., Mexico City 04510, Mexico.
Romero-Martínez BS; Departamento de Farmacología, Facultad de Medicina, Universidad Nacional Autónoma de México, Avenida Universidad No. 3000, Alcaldía de Coyoacán, C.P., Mexico City 04510, Mexico.
Solís-Chagoyán H; Centro de Investigación en Ciencias Cognitivas, Universidad Autónoma del Estado de Morelos, Avenida Universidad 1001, Col. Chamilpa, C.P., Cuernavaca 62209, Mexico.
Estrella-Parra EA; Laboratorio de Fitoquímica, Unidad de Biología Tecnología y Prototipos, FES-Iztacala, Universidad Nacional Autónoma de México, Avenida de los Barrios No. 1, Los Reyes Iztacala, C.P., Tlalnepantla 54090, Mexico.
Avila-Acevedo JG; Laboratorio de Fitoquímica, Unidad de Biología Tecnología y Prototipos, FES-Iztacala, Universidad Nacional Autónoma de México, Avenida de los Barrios No. 1, Los Reyes Iztacala, C.P., Tlalnepantla 54090, Mexico.
Gomez-Verjan JC; Dirección de Investigación, Instituto Nacional de Geriatría (INGER), Anillo Periférico. 2767, San Jerónimo Lídice, La Magdalena, C.P., Mexico City 10200, Mexico.
Reyes-García J; Departamento de Farmacología, Facultad de Medicina, Universidad Nacional Autónoma de México, Avenida Universidad No. 3000, Alcaldía de Coyoacán, C.P., Mexico City 04510, Mexico.
Casas-Hernández MF; Departamento de Farmacología, Facultad de Medicina, Universidad Nacional Autónoma de México, Avenida Universidad No. 3000, Alcaldía de Coyoacán, C.P., Mexico City 04510, Mexico.
Sommer B; Departamento de Investigación en Hiperreactividad Bronquial, Instituto Nacional de Enfermedades Respiratorias 'Ismael Cosio Villegas', Calz. De Tlalpan 4502, Col. Sección XVI, Alcaldía de Tlalpan, C.P., Mexico City 14080, Mexico.
Montaño LM; Departamento de Farmacología, Facultad de Medicina, Universidad Nacional Autónoma de México, Avenida Universidad No. 3000, Alcaldía de Coyoacán, C.P., Mexico City 04510, Mexico.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 May 12; Vol. 29 (10). Date of Electronic Publication: 2024 May 12.
Typ publikacji:
Journal Article
MeSH Terms:
Muscle, Smooth*/drug effects
Muscle, Smooth*/metabolism
Muscle Contraction*/drug effects
Quercetin*/pharmacology
Quercetin*/chemistry
Trachea*/drug effects
Trachea*/metabolism
Plant Extracts*/pharmacology
Plant Extracts*/chemistry
Chamaecyparis*/chemistry
Calcium*/metabolism
Animals ; Guinea Pigs ; Male ; Calcium Channel Blockers/pharmacology ; Histamine/metabolism ; Calcium Channels, L-Type/metabolism ; Plant Leaves/chemistry
Czasopismo naukowe
Tytuł:
Integrated Metabolomic and Transcriptomic Analysis Reveals the Underlying Antibacterial Mechanisms of the Phytonutrient Quercetin-Induced Fatty Acids Alteration in Staphylococcus aureus ATCC 27217.
Autorzy:
Yuan H; Key Laboratory of National Forestry and Grassland Administration/Beijing for Bamboo & Rattan Science and Technology, International Centre for Bamboo and Rattan, Beijing 100102, China.
Xun H; Key Laboratory of National Forestry and Grassland Administration/Beijing for Bamboo & Rattan Science and Technology, International Centre for Bamboo and Rattan, Beijing 100102, China.
Wang J; Key Laboratory of National Forestry and Grassland Administration/Beijing for Bamboo & Rattan Science and Technology, International Centre for Bamboo and Rattan, Beijing 100102, China.
Wang J; Key Laboratory of National Forestry and Grassland Administration/Beijing for Bamboo & Rattan Science and Technology, International Centre for Bamboo and Rattan, Beijing 100102, China.
Yao X; Key Laboratory of National Forestry and Grassland Administration/Beijing for Bamboo & Rattan Science and Technology, International Centre for Bamboo and Rattan, Beijing 100102, China.
Tang F; Key Laboratory of National Forestry and Grassland Administration/Beijing for Bamboo & Rattan Science and Technology, International Centre for Bamboo and Rattan, Beijing 100102, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 May 11; Vol. 29 (10). Date of Electronic Publication: 2024 May 11.
Typ publikacji:
Journal Article
MeSH Terms:
Quercetin*/pharmacology
Quercetin*/chemistry
Staphylococcus aureus*/drug effects
Fatty Acids*/metabolism
Fatty Acids*/biosynthesis
Anti-Bacterial Agents*/pharmacology
Molecular Docking Simulation ; Metabolomics/methods ; Transcriptome/drug effects ; Phytochemicals/pharmacology ; Phytochemicals/chemistry ; Gene Expression Profiling ; Cell Membrane/drug effects ; Cell Membrane/metabolism ; Gene Expression Regulation, Bacterial/drug effects ; Metabolome/drug effects ; Cell Membrane Permeability/drug effects
Czasopismo naukowe
Tytuł:
Anti-cytokine Storm Activity of Fraxin, Quercetin, and their Combination on Lipopolysaccharide-Induced Cytokine Storm in Mice: Implications in COVID-19.
Autorzy:
Shaker NS; Department of Pharmacology and Toxicology, Mustansiriyah University, College of Pharmacy, Baghdad, Iraq.
Sahib HB; Dean of College of Pharmacy, Al-Nahrain University, Baghdad, Iraq.
Tahseen NJ; Al-Bayan University, College of Pharmacy, Baghdad, Iraq.
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Źródło:
Iranian journal of medical sciences [Iran J Med Sci] 2024 May 01; Vol. 49 (5), pp. 322-331. Date of Electronic Publication: 2024 May 01 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Quercetin*/pharmacology
Quercetin*/therapeutic use
Cytokine Release Syndrome*/drug therapy
Lipopolysaccharides*/pharmacology
Animals ; Mice ; COVID-19 Drug Treatment ; Male ; COVID-19 ; Dexamethasone/pharmacology ; Dexamethasone/therapeutic use ; Interleukin-6/blood ; Interleukin-6/analysis ; Cytokines/drug effects ; Interleukin-1beta ; Tumor Necrosis Factor-alpha ; Disease Models, Animal ; Lung/drug effects ; Lung/pathology ; Coumarins
Czasopismo naukowe
Tytuł:
Exploring the Antiviral Potential of Esters of Cinnamic Acids with Quercetin.
Autorzy:
Manca V; Microbiology and Virology Unit, Department of Biomedical Sciences, University of Cagliari, Cittadella Universitaria, 09042 Monserrato, Italy.
Chianese A; Department of Experimental Medicine, University of Study of Campania 'Luigi Vanvitelli', Via Costantinopoli 16, 80138 Napoli, Italy.
Palmas V; Microbiology and Virology Unit, Department of Biomedical Sciences, University of Cagliari, Cittadella Universitaria, 09042 Monserrato, Italy.
Etzi F; Biology and Genetic Unit, Department of Biomedical Sciences, University of Cagliari, Cittadella Universitaria, 09042 Monserrato, Italy.
Zannella C; Department of Experimental Medicine, University of Study of Campania 'Luigi Vanvitelli', Via Costantinopoli 16, 80138 Napoli, Italy.
Moi D; Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria, 09042 Monserrato, Italy.
Secci F; Department of Chemical and Geological Sciences, University of Cagliari, Cittadella Universitaria, 09042 Monserrato, Italy.
Serreli G; Pathology Unit, Department of Biomedical Sciences, University of Cagliari, Cittadella Universitaria, 09042 Monserrato, Italy.
Sarais G; Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria, 09042 Monserrato, Italy.
Morone MV; Department of Experimental Medicine, University of Study of Campania 'Luigi Vanvitelli', Via Costantinopoli 16, 80138 Napoli, Italy.
Galdiero M; Department of Experimental Medicine, University of Study of Campania 'Luigi Vanvitelli', Via Costantinopoli 16, 80138 Napoli, Italy.
Onnis V; Department of Life and Environmental Sciences, University of Cagliari, Cittadella Universitaria, 09042 Monserrato, Italy.
Manzin A; Microbiology and Virology Unit, Department of Biomedical Sciences, University of Cagliari, Cittadella Universitaria, 09042 Monserrato, Italy.
Sanna G; Microbiology and Virology Unit, Department of Biomedical Sciences, University of Cagliari, Cittadella Universitaria, 09042 Monserrato, Italy.
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Źródło:
Viruses [Viruses] 2024 Apr 24; Vol. 16 (5). Date of Electronic Publication: 2024 Apr 24.
Typ publikacji:
Journal Article
MeSH Terms:
Antiviral Agents*/pharmacology
Antiviral Agents*/chemistry
Quercetin*/pharmacology
Quercetin*/chemistry
Quercetin*/analogs & derivatives
Cinnamates*/pharmacology
Cinnamates*/chemistry
Esters*/pharmacology
Esters*/chemistry
SARS-CoV-2*/drug effects
Virus Replication*/drug effects
Humans ; Animals ; COVID-19 Drug Treatment ; Chlorocebus aethiops ; Vero Cells ; COVID-19/virology ; Cell Line
Czasopismo naukowe
Tytuł:
Can Compounds of Natural Origin Be Important in Chemoprevention? Anticancer Properties of Quercetin, Resveratrol, and Curcumin-A Comprehensive Review.
Autorzy:
Cecerska-Heryć E; Department of Laboratory Medicine, Pomeranian Medical University of Szczecin, Powstancow Wielkopolskich 72, 70-111 Szczecin, Poland.
Wiśniewska Z; Department of Laboratory Medicine, Pomeranian Medical University of Szczecin, Powstancow Wielkopolskich 72, 70-111 Szczecin, Poland.
Serwin N; Department of Laboratory Medicine, Pomeranian Medical University of Szczecin, Powstancow Wielkopolskich 72, 70-111 Szczecin, Poland.
Polikowska A; Department of Laboratory Medicine, Pomeranian Medical University of Szczecin, Powstancow Wielkopolskich 72, 70-111 Szczecin, Poland.
Goszka M; Department of Laboratory Medicine, Pomeranian Medical University of Szczecin, Powstancow Wielkopolskich 72, 70-111 Szczecin, Poland.
Engwert W; Department of Laboratory Medicine, Pomeranian Medical University of Szczecin, Powstancow Wielkopolskich 72, 70-111 Szczecin, Poland.
Michałów J; Department of Laboratory Medicine, Pomeranian Medical University of Szczecin, Powstancow Wielkopolskich 72, 70-111 Szczecin, Poland.
Pękała M; Department of Laboratory Medicine, Pomeranian Medical University of Szczecin, Powstancow Wielkopolskich 72, 70-111 Szczecin, Poland.
Budkowska M; Department of Medical Analytics, Pomeranian Medical University of Szczecin, Powstancow Wielkopolskich 72, 70-111 Szczecin, Poland.
Michalczyk A; Department of Psychiatry, Pomeranian Medical University of Szczecin, Broniewskiego 26, 71-460 Szczecin, Poland.
Dołęgowska B; Department of Laboratory Medicine, Pomeranian Medical University of Szczecin, Powstancow Wielkopolskich 72, 70-111 Szczecin, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Apr 19; Vol. 25 (8). Date of Electronic Publication: 2024 Apr 19.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Quercetin*/pharmacology
Quercetin*/therapeutic use
Quercetin*/chemistry
Curcumin*/pharmacology
Curcumin*/therapeutic use
Resveratrol*/pharmacology
Antioxidants*/pharmacology
Humans ; Animals ; Neoplasms/prevention & control ; Neoplasms/drug therapy ; Neoplasms/metabolism ; Chemoprevention/methods ; Antineoplastic Agents/pharmacology ; Polyphenols/pharmacology ; Polyphenols/chemistry
Czasopismo naukowe
Tytuł:
Quercetin alleviates chronic unpredictable mild stress-induced depression-like behavior by inhibiting NMDAR1 with α2δ-1 in rats.
Autorzy:
Wang M; College of Integrative Chinese and Western Medicine, Hebei University of Chinese Medicine, Shijiazhuang, China.
Wei X; College of Integrative Chinese and Western Medicine, Hebei University of Chinese Medicine, Shijiazhuang, China.
Jia Y; College of Basic Medical Sciences, Hebei University of Chinese Medicine, Shijiazhuang, China.
Wang C; College of Basic Medical Sciences, Hebei University of Chinese Medicine, Shijiazhuang, China.
Wang X; College of Integrative Chinese and Western Medicine, Hebei University of Chinese Medicine, Shijiazhuang, China.
Zhang X; College of Integrative Chinese and Western Medicine, Hebei University of Chinese Medicine, Shijiazhuang, China.
Li D; Department of Medicine, University of Missouri, Columbia, Missouri, USA.
Wang Y; College of Basic Medical Sciences, Hebei University of Chinese Medicine, Shijiazhuang, China.
Gao Y; College of Basic Medical Sciences, Hebei University of Chinese Medicine, Shijiazhuang, China.; Hebei International Cooperation Center for Ion channel Function and Innovative Traditional Chinese Medicine, Shijiazhuang, China.; Hebei Key Laboratory of Chinese Medicine Research on Cardio-Cerebrovascular Disease, Shijiazhuang, China.
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Źródło:
CNS neuroscience & therapeutics [CNS Neurosci Ther] 2024 Apr; Vol. 30 (4), pp. e14724.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Receptors, N-Methyl-D-Aspartate*
Quercetin*/pharmacology
Quercetin*/therapeutic use
Humans ; Animals ; Rats ; Depression/drug therapy ; Depression/etiology ; Hypothalamo-Hypophyseal System ; Pituitary-Adrenal System ; Antidepressive Agents/pharmacology ; Antidepressive Agents/therapeutic use
Czasopismo naukowe
Tytuł:
Hyperoside mitigates photoreceptor degeneration in part by targeting cGAS and suppressing DNA-induced microglial activation.
Autorzy:
Li D; Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200437, China.
Chang J; Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200437, China.
Wang Y; Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200437, China.
Du X; Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200437, China.; Clinical Research Institute of Integrative Medicine, Shanghai Academy of Traditional Chinese Medicine, Shanghai, 200437, China.
Xu J; Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200437, China.; Clinical Research Institute of Integrative Medicine, Shanghai Academy of Traditional Chinese Medicine, Shanghai, 200437, China.
Cui J; Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200437, China.; Clinical Research Institute of Integrative Medicine, Shanghai Academy of Traditional Chinese Medicine, Shanghai, 200437, China.
Zhang T; Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200437, China.; Clinical Research Institute of Integrative Medicine, Shanghai Academy of Traditional Chinese Medicine, Shanghai, 200437, China.
Chen Y; Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200437, China. .; Clinical Research Institute of Integrative Medicine, Shanghai Academy of Traditional Chinese Medicine, Shanghai, 200437, China. .; Laboratory of Clinical and Molecular Pharmacology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200437, China. .
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Źródło:
Acta neuropathologica communications [Acta Neuropathol Commun] 2024 May 16; Vol. 12 (1), pp. 76. Date of Electronic Publication: 2024 May 16.
Typ publikacji:
Journal Article
MeSH Terms:
Microglia*/drug effects
Microglia*/metabolism
Microglia*/pathology
Quercetin*/pharmacology
Quercetin*/analogs & derivatives
Retinal Degeneration*/pathology
Retinal Degeneration*/metabolism
Retinal Degeneration*/drug therapy
Retinal Degeneration*/prevention & control
Nucleotidyltransferases*/metabolism
Animals ; Mice ; Mice, Inbred C57BL ; DNA/metabolism ; Cell Line ; Photoreceptor Cells, Vertebrate/drug effects ; Photoreceptor Cells, Vertebrate/pathology ; Photoreceptor Cells, Vertebrate/metabolism ; Male
Czasopismo naukowe
Tytuł:
Quercetin Induces Mitochondrial Apoptosis and Downregulates Ganglioside GD3 Expression in Melanoma Cells.
Autorzy:
Seo SY; Department of Biological Science, College of Natural Sciences, Wonkwang University, Iksan 54538, Jeonbuk, Republic of Korea.; Division of Animal Diseases & Health, National Institute of Animal Science, Rural Development Administration, 1500 Kongjwipatjwi-ro, Iseo-myeon, Wanju-gun 55365, Jeonbuk, Republic of Korea.
Ju WS; Department of Biological Science, College of Natural Sciences, Wonkwang University, Iksan 54538, Jeonbuk, Republic of Korea.; Animal Biotechnology Division, National Institute of Animal Science, Rural Development Administration, 1500 Kongjwipatjwi-ro, Iseo-myeon, Wanju-gun 55365, Jeonbuk, Republic of Korea.
Kim K; Department of Biological Science, College of Natural Sciences, Wonkwang University, Iksan 54538, Jeonbuk, Republic of Korea.
Kim J; Department of Biological Science, College of Natural Sciences, Wonkwang University, Iksan 54538, Jeonbuk, Republic of Korea.
Yu JO; Department of Biological Science, College of Natural Sciences, Wonkwang University, Iksan 54538, Jeonbuk, Republic of Korea.
Ryu JS; Division of Biodrug Evaluation, New Drug Development Center, Osong Medical Innovation Foundation (K-Bio Health), Cheongju 28160, Chungbuk, Republic of Korea.
Kim JS; Primate Resources Center (PRC), Korea Research Institute of Bioscience and Biotechnology (KRIBB), Jeongeup 56216, Jeonbuk, Republic of Korea.
Lee HA; Center for Animal Resources Development, Wonkwang University, Iksan 54538, Jeonbuk, Republic of Korea.
Koo DB; Department of Biotechnology, College of Engineering, Daegu University, Gyeongsan 38453, Gyeongbuk, Republic of Korea.
Choo YK; Department of Biological Science, College of Natural Sciences, Wonkwang University, Iksan 54538, Jeonbuk, Republic of Korea.; Institute for Glycoscience, Wonkwang University, Iksan 54538, Jeonbuk, Republic of Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 May 09; Vol. 25 (10). Date of Electronic Publication: 2024 May 09.
Typ publikacji:
Journal Article
MeSH Terms:
Quercetin*/pharmacology
Melanoma*/metabolism
Melanoma*/drug therapy
Melanoma*/pathology
Apoptosis*/drug effects
Mitochondria*/metabolism
Mitochondria*/drug effects
Gangliosides*/metabolism
Humans ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Signal Transduction/drug effects ; Down-Regulation/drug effects ; Gene Expression Regulation, Neoplastic/drug effects ; Cell Movement/drug effects ; Skin Neoplasms/metabolism ; Skin Neoplasms/drug therapy ; Skin Neoplasms/pathology ; Proto-Oncogene Proteins c-akt/metabolism
Czasopismo naukowe
Tytuł:
Neurotherapeutic effects of quercetin-loaded nanoparticles and Biochanin-A extracted from Trifolium alexandrinum on PI3K/Akt/GSK-3β signaling in the cerebral cortex of male diabetic rats.
Autorzy:
Newairy AA; Faculty of Science, Department of Biochemistry, Alexandria University, Alexandria, Egypt.
Hamaad FA; Faculty of Science, Department of Biochemistry, Alexandria University, Alexandria, Egypt.
Wahby MM; Faculty of Science, Department of Biochemistry, Alexandria University, Alexandria, Egypt.
Ghoneum M; Department of Surgery, Charles R. Drew University of Medicine and Science, Los Angeles, California, United States of America.; Department of Surgery, University of California Los Angeles, Los Angeles, California, United States of America.
Abdou HM; Faulty of Science, Department of Zoology, Alexandria University, Alexandria, Egypt.
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Źródło:
PloS one [PLoS One] 2024 Apr 29; Vol. 19 (4), pp. e0301355. Date of Electronic Publication: 2024 Apr 29 (Print Publication: 2024).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cerebral Cortex*/drug effects
Cerebral Cortex*/metabolism
Cerebral Cortex*/pathology
Diabetes Mellitus, Experimental*/drug therapy
Diabetes Mellitus, Experimental*/metabolism
Diabetes Mellitus, Experimental*/complications
Glycogen Synthase Kinase 3 beta*/metabolism
Nanoparticles*/chemistry
Phosphatidylinositol 3-Kinases*/metabolism
Proto-Oncogene Proteins c-akt*/metabolism
Quercetin*/pharmacology
Quercetin*/therapeutic use
Quercetin*/administration & dosage
Trifolium*/chemistry
Animals ; Male ; Rats ; Plant Extracts/pharmacology ; Plant Extracts/therapeutic use ; Rats, Wistar ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł:
Identifying transcriptomic profiles of iron-quercetin complex treated peripheral blood mononuclear cells from healthy volunteers and diabetic patients.
Autorzy:
Innuan P; Molecular Imaging and Therapy Research Unit, Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, 50200, Thailand.; Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, 50200, Thailand.
Sirikul C; Division of Transfusion Science, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, 50200, Thailand.
Anukul N; Division of Transfusion Science, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, 50200, Thailand.
Rolin G; INSERM CIC-1431, CHU Besançon, 25000, Besançon, France.
Dechsupa N; Molecular Imaging and Therapy Research Unit, Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, 50200, Thailand.; Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, 50200, Thailand.
Kantapan J; Molecular Imaging and Therapy Research Unit, Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, 50200, Thailand. .; Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, 50200, Thailand. .
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Źródło:
Scientific reports [Sci Rep] 2024 Apr 24; Vol. 14 (1), pp. 9441. Date of Electronic Publication: 2024 Apr 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Leukocytes, Mononuclear*/metabolism
Leukocytes, Mononuclear*/drug effects
Quercetin*/pharmacology
Transcriptome*/drug effects
Iron*/metabolism
Healthy Volunteers*
Diabetes Mellitus*/drug therapy
Diabetes Mellitus*/genetics
Diabetes Mellitus*/metabolism
Humans ; Gene Expression Profiling ; Male ; Female ; Adult
Czasopismo naukowe
Tytuł:
Features of the Effect of Quercetin on Different Genotypes of Wheat under Hypoxia.
Autorzy:
Fedoreyeva LI; All-Russia Research Institute of Agricultural Biotechnology, Timiryazevskaya 42, 127550 Moscow, Russia.
Lazareva EM; All-Russia Research Institute of Agricultural Biotechnology, Timiryazevskaya 42, 127550 Moscow, Russia.; Biological Department, M.V. Lomonosov Moscow State University, Leninskie Gory 1, 119991 Moscow, Russia.
Kononenko NV; All-Russia Research Institute of Agricultural Biotechnology, Timiryazevskaya 42, 127550 Moscow, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Apr 19; Vol. 25 (8). Date of Electronic Publication: 2024 Apr 19.
Typ publikacji:
Journal Article
MeSH Terms:
Triticum*/genetics
Triticum*/drug effects
Triticum*/metabolism
Quercetin*/pharmacology
Genotype*
Antioxidants*/pharmacology
Reactive Oxygen Species/metabolism ; Oxidative Stress/drug effects ; Stress, Physiological/drug effects ; Superoxide Dismutase/metabolism ; Superoxide Dismutase/genetics ; Oxygen/metabolism
Czasopismo naukowe
Tytuł:
Quercetin Impairs the Growth of Uveal Melanoma Cells by Interfering with Glucose Uptake and Metabolism.
Autorzy:
Tura A; Department of Ophthalmology, University of Lübeck, Ratzeburger Allee 160, 23562 Luebeck, Germany.
Herfs V; Department of Ophthalmology, University of Lübeck, Ratzeburger Allee 160, 23562 Luebeck, Germany.
Maaßen T; Department of Ophthalmology, University of Lübeck, Ratzeburger Allee 160, 23562 Luebeck, Germany.
Zuo H; Department of Ophthalmology, University of Lübeck, Ratzeburger Allee 160, 23562 Luebeck, Germany.
Vardanyan S; Department of Ophthalmology, University of Lübeck, Ratzeburger Allee 160, 23562 Luebeck, Germany.
Prasuhn M; Department of Ophthalmology, University of Lübeck, Ratzeburger Allee 160, 23562 Luebeck, Germany.
Ranjbar M; Department of Ophthalmology, University of Lübeck, Ratzeburger Allee 160, 23562 Luebeck, Germany.
Kakkassery V; Department of Ophthalmology, University of Lübeck, Ratzeburger Allee 160, 23562 Luebeck, Germany.
Grisanti S; Department of Ophthalmology, University of Lübeck, Ratzeburger Allee 160, 23562 Luebeck, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Apr 12; Vol. 25 (8). Date of Electronic Publication: 2024 Apr 12.
Typ publikacji:
Journal Article
MeSH Terms:
Quercetin*/pharmacology
Melanoma*/metabolism
Melanoma*/pathology
Melanoma*/genetics
Melanoma*/drug therapy
Uveal Neoplasms*/metabolism
Uveal Neoplasms*/genetics
Uveal Neoplasms*/pathology
Uveal Neoplasms*/drug therapy
Glucose*/metabolism
Glycolysis*/drug effects
Cell Proliferation*/drug effects
Humans ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic/drug effects ; Pentose Phosphate Pathway/drug effects ; Chromosomes, Human, Pair 3/genetics
SCR Disease Name:
Uveal melanoma
Czasopismo naukowe
Tytuł:
Antimicrobial Activity and Phytochemical Characterization of Baccharis concava Pers., a Native Plant of the Central Chilean Coast.
Autorzy:
Rodríguez-Díaz M; Escuela de Química y Farmacia, Facultad de Medicina, Universidad Andres Bello, Santiago 8370134, Chile.
Pérez FE; Escuela de Química y Farmacia, Facultad de Medicina, Universidad Andres Bello, Santiago 8370134, Chile.
Manosalva PM; Escuela de Química y Farmacia, Facultad de Medicina, Universidad Andres Bello, Santiago 8370134, Chile.
Cerda JI; Escuela de Química y Farmacia, Facultad de Medicina, Universidad Andres Bello, Santiago 8370134, Chile.
Martínez-Contreras CF; Escuela de Química y Farmacia, Facultad de Medicina, Universidad Andres Bello, Santiago 8370134, Chile.
Mora AY; Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, Santiago 8380492, Chile.
Villagra NA; Escuela de Tecnología Médica, Facultad de Salud, Universidad Santo Tomas, Santiago 8370003, Chile.
Bucarey SA; Departamento de Ciencias Biológicas, Facultad de Ciencias Veterinarias y Pecuarias, Universidad de Chile, Santiago 8820808, Chile.
Barriga A; Centro de Estudios Para el Desarrollo de la Química (CEPEDEQ), Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, Santiago 8380492, Chile.
Escobar J; Laboratorio de Química Biológica, Facultad de Ciencias, Pontificia Universidad Católica de Valparaíso, Valparaíso 2340000, Chile.
Martínez JL; Departamento de Ingeniería Metalúrgica, Facultad de Ingeniería, Universidad de Santiago de Chile, Estación Central, Santiago 9160000, Chile.
Hidalgo AA; Escuela de Química y Farmacia, Facultad de Medicina, Universidad Andres Bello, Santiago 8370134, Chile.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2024 Apr 07; Vol. 29 (7). Date of Electronic Publication: 2024 Apr 07.
Typ publikacji:
Journal Article
MeSH Terms:
Quercetin*
Baccharis*
Quinic Acid/*analogs & derivatives
Chile ; Tandem Mass Spectrometry ; Phytochemicals/pharmacology ; Flavonoids/pharmacology ; Plant Extracts/pharmacology
Czasopismo naukowe
Tytuł:
Quercetin Improves Barrier Properties in Porcine Small Intestine but Not in Peyer's Patches.
Autorzy:
Cornelius V; Institute of Veterinary Physiology, School of Veterinary Medicine, Freie Universität Berlin, 14163 Berlin, Germany.
Droessler L; Institute of Veterinary Physiology, School of Veterinary Medicine, Freie Universität Berlin, 14163 Berlin, Germany.
Amasheh S; Institute of Veterinary Physiology, School of Veterinary Medicine, Freie Universität Berlin, 14163 Berlin, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 26; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 26.
Typ publikacji:
Journal Article
MeSH Terms:
Quercetin*/pharmacology
Quercetin*/metabolism
Peyer's Patches*/metabolism
Animals ; Swine ; Claudin-4/metabolism ; Claudin-2/metabolism ; Claudin-1/metabolism ; Intestine, Small/metabolism ; Claudins/metabolism ; Tight Junctions/metabolism ; Mannitol/pharmacology
Czasopismo naukowe
Tytuł:
Computational identification of natural senotherapeutic compounds that mimic dasatinib based on gene expression data.
Autorzy:
Meiners F; Institute for Biostatistics and Informatics in Medicine and Ageing Research, Rostock University Medical Center, Rostock, Germany.
Hinz B; Institute of Pharmacology and Toxicology, Rostock University Medical Center, Rostock, Germany.
Boeckmann L; Clinic and Policlinic for Dermatology and Venerology, University Medical Center Rostock, Strempelstr. 13, 18057, Rostock, Germany.
Secci R; Institute for Biostatistics and Informatics in Medicine and Ageing Research, Rostock University Medical Center, Rostock, Germany.
Sueto S; Institute for Biostatistics and Informatics in Medicine and Ageing Research, Rostock University Medical Center, Rostock, Germany.
Kuepfer L; Institute for Systems Medicine with Focus on Organ Interaction, University Hospital RWTH Aachen, Aachen, Germany.
Fuellen G; Institute for Biostatistics and Informatics in Medicine and Ageing Research, Rostock University Medical Center, Rostock, Germany. .
Barrantes I; Institute for Biostatistics and Informatics in Medicine and Ageing Research, Rostock University Medical Center, Rostock, Germany.
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Źródło:
Scientific reports [Sci Rep] 2024 Mar 15; Vol. 14 (1), pp. 6286. Date of Electronic Publication: 2024 Mar 15.
Typ publikacji:
Journal Article
MeSH Terms:
Quercetin*/pharmacology
Quercetin*/therapeutic use
Senotherapeutics*
Dasatinib/pharmacology ; Dasatinib/therapeutic use ; Cellular Senescence ; Gene Expression
Czasopismo naukowe

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