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Tytuł:
Leukotriene receptor antagonism with montelukast as a possible therapeutic for venous thromboembolism prophylaxis: An observational study.
Autorzy:
Sutton SS; Dorn Research Institute, Columbia VA Health Care System, Columbia, South Carolina & Department of Clinical Pharmacy and Outcomes Sciences, College of Pharmacy, University of South Carolina, Columbia, SC, USA.
Magagnoli J; Dorn Research Institute, Columbia VA Health Care System, Columbia, South Carolina & Department of Clinical Pharmacy and Outcomes Sciences, College of Pharmacy, University of South Carolina, Columbia, SC, USA. Electronic address: .
Cummings TH; Dorn Research Institute, Columbia VA Health Care System, Columbia, South Carolina & Department of Clinical Pharmacy and Outcomes Sciences, College of Pharmacy, University of South Carolina, Columbia, SC, USA.
Hardin JW; Dorn Research Institute, Columbia VA Health Care System, Columbia, South Carolina & Department of Epidemiology & Biostatistics, University of South Carolina, Columbia, SC, USA.
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Źródło:
Prostaglandins & other lipid mediators [Prostaglandins Other Lipid Mediat] 2022 Aug; Vol. 161, pp. 106649. Date of Electronic Publication: 2022 May 18.
Typ publikacji:
Journal Article; Observational Study; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Quinolines*/pharmacology
Quinolines*/therapeutic use
Venous Thromboembolism*/drug therapy
Venous Thromboembolism*/prevention & control
Acetates/pharmacology ; Acetates/therapeutic use ; Cyclopropanes ; Humans ; Leukotriene Antagonists/pharmacology ; Leukotriene Antagonists/therapeutic use ; Leukotrienes ; Receptors, Leukotriene/metabolism ; Retrospective Studies ; Sulfides
Czasopismo naukowe
Szczegóły
Tytuł:
Genome-Wide CRISPR/Cas9 Library Screening Identified that DUSP4 Deficiency Induces Lenvatinib Resistance in Hepatocellular Carcinoma.
Autorzy:
Huang S; Department of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China.; Heyuan people's Hospital, Heyuan 517000, China.; School of Medicine, South China University of Technology, Guangzhou 510080, China.; The Second School of Clinical Medicine, Southern Medical University, Guangzhou, 510515, China.
Ma Z; Department of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China.; Shantou University of Medical College, Shantou, 515000, China.
Zhou Q; Department of General Surgery, Hui Ya Hospital of The First Affiliated Hospital of Sun Yat-Sen University; Department of Liver Surgery, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510080, China.
Wang A; Department of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China.
Gong Y; Department of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China.; The Second School of Clinical Medicine, Southern Medical University, Guangzhou, 510515, China.; Department of Hepatobiliary Surgery, the Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou, 510095, China.
Li Z; Department of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China.; School of Medicine, South China University of Technology, Guangzhou 510080, China.
Wang S; Department of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China.; The Second School of Clinical Medicine, Southern Medical University, Guangzhou, 510515, China.
Yan Q; Department of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China.; School of Medicine, South China University of Technology, Guangzhou 510080, China.
Wang D; Organ Transplant Centre, The First Affiliated Hospital, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Organ Donation and Transplant Immunology, Guangdong Provincial International Cooperation Base of Science and Technology (Organ Transplantation), Guangzhou 510080, China.
Hou B; Department of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China.; Heyuan people's Hospital, Heyuan 517000, China.; School of Medicine, South China University of Technology, Guangzhou 510080, China.; The Second School of Clinical Medicine, Southern Medical University, Guangzhou, 510515, China.
Zhang C; Department of General Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China.; Heyuan people's Hospital, Heyuan 517000, China.; School of Medicine, South China University of Technology, Guangzhou 510080, China.; The Second School of Clinical Medicine, Southern Medical University, Guangzhou, 510515, China.
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Źródło:
International journal of biological sciences [Int J Biol Sci] 2022 Jul 04; Vol. 18 (11), pp. 4357-4371. Date of Electronic Publication: 2022 Jul 04 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Hepatocellular*/drug therapy
Carcinoma, Hepatocellular*/genetics
Carcinoma, Hepatocellular*/metabolism
Drug Resistance, Neoplasm*/genetics
Dual-Specificity Phosphatases*/genetics
Dual-Specificity Phosphatases*/metabolism
Liver Neoplasms*/drug therapy
Liver Neoplasms*/genetics
Liver Neoplasms*/metabolism
Quinolines*/pharmacology
Quinolines*/therapeutic use
Animals ; CRISPR-Cas Systems/genetics ; Cell Line, Tumor ; Humans ; Mice ; Mitogen-Activated Protein Kinase Kinases/genetics ; Mitogen-Activated Protein Kinase Kinases/metabolism ; Phenylurea Compounds ; Protein Kinase Inhibitors/pharmacology
Czasopismo naukowe
Szczegóły
Tytuł:
Evolution of the Dearomative Functionalization of Activated Quinolines and Isoquinolines: Expansion of the Electrophile Scope.
Autorzy:
Kischkewitz M; Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA, UK.
Marinic B; Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA, UK.
Kratena N; Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA, UK.
Lai Y; Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA, UK.
Hepburn HB; Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA, UK.
Dow M; Chemical Development, Pharmaceutical Technology & Development, Operations, AstraZeneca, Macclesfield, SK10 2NA, UK.
Christensen KE; Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA, UK.
Donohoe TJ; Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford, OX1 3TA, UK.
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Źródło:
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2022 Jul 04; Vol. 61 (27), pp. e202204682. Date of Electronic Publication: 2022 May 13.
Typ publikacji:
Journal Article
MeSH Terms:
Quinolines*
Rhodium*
Catalysis ; Electrons ; Isoquinolines ; Molecular Structure
Czasopismo naukowe
Szczegóły
Tytuł:
Multi-Substituted Quinolines as HIV-1 Integrase Allosteric Inhibitors.
Autorzy:
Dinh LP; Department of Chemistry, University of South Alabama, Mobile, AL 36688, USA.
Sun J; Department of Chemistry and Biochemistry, University of Southern Mississippi, Hattiesburg, MS 39406, USA.
Glenn CD; Department of Chemistry, University of South Alabama, Mobile, AL 36688, USA.
Patel K; Department of Chemistry and Biochemistry, University of Southern Mississippi, Hattiesburg, MS 39406, USA.
Pigza JA; Department of Chemistry and Biochemistry, University of Southern Mississippi, Hattiesburg, MS 39406, USA.
Donahue MG; Department of Chemistry and Biochemistry, University of Southern Mississippi, Hattiesburg, MS 39406, USA.
Yet L; Department of Chemistry, University of South Alabama, Mobile, AL 36688, USA.
Kessl JJ; Department of Chemistry and Biochemistry, University of Southern Mississippi, Hattiesburg, MS 39406, USA.
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Źródło:
Viruses [Viruses] 2022 Jul 02; Vol. 14 (7). Date of Electronic Publication: 2022 Jul 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
MeSH Terms:
HIV Integrase*/metabolism
HIV Integrase Inhibitors*/chemistry
HIV Integrase Inhibitors*/pharmacology
HIV-1*/metabolism
Quinolines*/pharmacology
Allosteric Regulation ; Antiviral Agents/pharmacology ; Virus Replication
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Computational targeting of allosteric site of MEK1 by quinoline-based molecules.
Autorzy:
Singh R; Structural Bioinformatics Lab, CSIR-Institute of Himalayan Bioresource Technology (CSIR-IHBT), Palampur, Himachal Pradesh, India.; Biotechnology Division, CSIR-IHBT, Palampur, Himachal Pradesh, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.
Bhardwaj VK; Structural Bioinformatics Lab, CSIR-Institute of Himalayan Bioresource Technology (CSIR-IHBT), Palampur, Himachal Pradesh, India.; Biotechnology Division, CSIR-IHBT, Palampur, Himachal Pradesh, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.
Purohit R; Structural Bioinformatics Lab, CSIR-Institute of Himalayan Bioresource Technology (CSIR-IHBT), Palampur, Himachal Pradesh, India.; Biotechnology Division, CSIR-IHBT, Palampur, Himachal Pradesh, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.
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Źródło:
Cell biochemistry and function [Cell Biochem Funct] 2022 Jul; Vol. 40 (5), pp. 481-490. Date of Electronic Publication: 2022 May 23.
Typ publikacji:
Journal Article
MeSH Terms:
Protein Kinase Inhibitors*/chemistry
Protein Kinase Inhibitors*/pharmacology
Quinolines*/pharmacology
Allosteric Site ; MAP Kinase Kinase 1/chemistry ; MAP Kinase Kinase 1/metabolism ; Molecular Docking Simulation ; Molecular Dynamics Simulation
Czasopismo naukowe
Szczegóły
Tytuł:
Xihuang Pill enhances anticancer effect of anlotinib by regulating gut microbiota composition and tumor angiogenesis pathway.
Autorzy:
Cao B; National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, China.
Wang S; National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, China.
Li R; Research Center for Clinical and Translational Medicine, Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
Wang Z; National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, China.
Li T; National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, China.
Zhang Y; National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, China.
Dong B; National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, China.
Li Y; National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, China.
Lin M; National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, China.
Li X; Research Center for Clinical and Translational Medicine, Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
Xiao X; China Military Institute of Chinese Medicine, Fifth Medical Center of Chinese PLA General Hospital, Beijing, China. Electronic address: .
Li C; National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, China. Electronic address: chunyu_.
Li G; National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, China. Electronic address: .
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Źródło:
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2022 Jul; Vol. 151, pp. 113081. Date of Electronic Publication: 2022 May 20.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Lewis Lung*/drug therapy
Drugs, Chinese Herbal*/pharmacology
Drugs, Chinese Herbal*/therapeutic use
Gastrointestinal Microbiome*
Lung Neoplasms*/pathology
Quinolines*/pharmacology
Quinolines*/therapeutic use
Animals ; Humans ; Indoles ; Mice
Czasopismo naukowe
Szczegóły
Tytuł:
Efficacy and Safety of Lenvatinib in Anaplastic Thyroid Carcinoma: A Meta-Analysis.
Autorzy:
Huang D; Department of Thyroid and Neck Tumor, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer, Tianjin, China.
Zhang J; Department of Thyroid and Neck Tumor, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer, Tianjin, China.
Zheng X; Department of Thyroid and Neck Tumor, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer, Tianjin, China.
Gao M; Department of Thyroid and Neck Tumor, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Department of Thyroid and Breast Surgery, Tianjin Union Medical Center, Tianjin, China.; Tianjin Key Laboratory of General Surgery Inconstruction, Tianjin Union Medical Center, Tianjin, China.
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Źródło:
Frontiers in endocrinology [Front Endocrinol (Lausanne)] 2022 Jun 30; Vol. 13, pp. 920857. Date of Electronic Publication: 2022 Jun 30 (Print Publication: 2022).
Typ publikacji:
Journal Article; Meta-Analysis; Systematic Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Antineoplastic Agents*/adverse effects
Antineoplastic Agents*/therapeutic use
Phenylurea Compounds*/adverse effects
Phenylurea Compounds*/therapeutic use
Quinolines*/adverse effects
Quinolines*/therapeutic use
Thyroid Carcinoma, Anaplastic*/drug therapy
Thyroid Carcinoma, Anaplastic*/pathology
Thyroid Neoplasms*/drug therapy
Thyroid Neoplasms*/pathology
Humans
Czasopismo naukowe
Szczegóły
Tytuł:
Domino Nitro Reduction-Friedländer Heterocyclization for the Preparation of Quinolines.
Autorzy:
Fobi K; Department of Chemistry, Oklahoma State University, Stillwater, OK 74078-3071, USA.
Bunce RA; Department of Chemistry, Oklahoma State University, Stillwater, OK 74078-3071, USA.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Jun 27; Vol. 27 (13). Date of Electronic Publication: 2022 Jun 27.
Typ publikacji:
Journal Article
MeSH Terms:
Quinolines*
Cyclization ; Esters ; Ketones
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
How has mass drug administration with dihydroartemisinin-piperaquine impacted molecular markers of drug resistance? A systematic review.
Autorzy:
Moss S; Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK. .
Mańko E; Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK.
Krishna S; Institute of Infection and Immunity, St George's University of London, London, UK.
Campino S; Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK.
Clark TG; Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK.; Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UK.
Last A; Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK. .
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Źródło:
Malaria journal [Malar J] 2022 Jun 11; Vol. 21 (1), pp. 186. Date of Electronic Publication: 2022 Jun 11.
Typ publikacji:
Journal Article; Review; Systematic Review
MeSH Terms:
Antimalarials*/pharmacology
Antimalarials*/therapeutic use
Artemisinins*/pharmacology
Artemisinins*/therapeutic use
Malaria, Falciparum*/drug therapy
Malaria, Falciparum*/epidemiology
Quinolines*/pharmacology
Quinolines*/therapeutic use
Biomarkers ; Drug Resistance/genetics ; Humans ; Mass Drug Administration ; Piperazines ; Plasmodium falciparum/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Synthesis of a new series of quinoline/pyridine indole-3-sulfonamide hybrids as selective carbonic anhydrase IX inhibitors.
Autorzy:
Singh P; Department of Chemical Sciences, National Institute of Pharmaceutical Education and Research (NIPER), Balanagar, Hyderabad 500037, India.
Sridhar Goud N; Department of Chemical Sciences, National Institute of Pharmaceutical Education and Research (NIPER), Balanagar, Hyderabad 500037, India; Department of Neuroimaging and Interventional Radiology (NIIIR) National Institute of Mental Health and Neuro Sciences (NIMHANS), Bengaluru 560027, India.
Swain B; Department of Chemical Sciences, National Institute of Pharmaceutical Education and Research (NIPER), Balanagar, Hyderabad 500037, India.
Kumar Sahoo S; Department of Chemical Sciences, National Institute of Pharmaceutical Education and Research (NIPER), Balanagar, Hyderabad 500037, India.
Choli A; Department of Chemical Sciences, National Institute of Pharmaceutical Education and Research (NIPER), Balanagar, Hyderabad 500037, India.
Angeli A; Università degl iStudi di Firenze, Neurofarba Dept., Sezione di ScienzeFarmaceutiche e Nutraceutiche, Via Ugo Schiff 6, 50019 Sesto Fiorentino, Florence, Italy.
Singh Kushwah B; Department of Pharmaceurical Analysis, National Institute of Pharmaceutical Education and Research (NIPER), Balanagar, Hyderabad 500037, India.
Madhavi Yaddanapudi V; Department of Chemical Sciences, National Institute of Pharmaceutical Education and Research (NIPER), Balanagar, Hyderabad 500037, India. Electronic address: .
Supuran CT; Università degl iStudi di Firenze, Neurofarba Dept., Sezione di ScienzeFarmaceutiche e Nutraceutiche, Via Ugo Schiff 6, 50019 Sesto Fiorentino, Florence, Italy. Electronic address: .
Arifuddin M; Department of Chemical Sciences, National Institute of Pharmaceutical Education and Research (NIPER), Balanagar, Hyderabad 500037, India. Electronic address: .
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Źródło:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2022 Aug 15; Vol. 70, pp. 128809. Date of Electronic Publication: 2022 May 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Neoplasms*/drug therapy
Quinolines*/pharmacology
Antigens, Neoplasm ; Carbonic Anhydrase IX/metabolism ; Carbonic Anhydrase Inhibitors/pharmacology ; Humans ; Indoles/pharmacology ; Isoenzymes ; Pyridines ; Structure-Activity Relationship ; Sulfonamides/pharmacology
Czasopismo naukowe
Szczegóły
Tytuł:
Photouncaging of Carboxylic Acids from Cyanine Dyes with Near-Infrared Light.
Autorzy:
Janeková H; Department of Chemistry, University of Zurich, Wintherthurerstrasse 190, 8057, Zurich, Switzerland.
Russo M; Department of Chemistry, University of Zurich, Wintherthurerstrasse 190, 8057, Zurich, Switzerland.
Ziegler U; Center for Microscopy and Image Analysis, University of Zurich, Wintherthurerstrasse 190, 8057, Zurich, Switzerland.
Štacko P; Department of Chemistry, University of Zurich, Wintherthurerstrasse 190, 8057, Zurich, Switzerland.
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Źródło:
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2022 Aug 15; Vol. 61 (33), pp. e202204391. Date of Electronic Publication: 2022 Jun 01.
Typ publikacji:
Journal Article
MeSH Terms:
Coloring Agents*
Quinolines*
Carboxylic Acids ; Fluorescent Dyes ; HeLa Cells ; Humans ; Infrared Rays ; Photochemistry
Czasopismo naukowe
Szczegóły
Tytuł:
N -Oxide-Induced Ugi Reaction: A Rapid Access to Quinoline-C2-amino Amides via Deoxygenative C(sp )-H Functionalization.
Autorzy:
Anugu N; Department of Chemistry, National Institute of Technology Warangal Warangal, Telangana-506004, India.
Thunga S; Department of Chemistry, National Institute of Technology Warangal Warangal, Telangana-506004, India.
Poshala S; Department of Chemistry, National Institute of Technology Warangal Warangal, Telangana-506004, India.
Kokatla HP; Department of Chemistry, National Institute of Technology Warangal Warangal, Telangana-506004, India.
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Źródło:
The Journal of organic chemistry [J Org Chem] 2022 Aug 05; Vol. 87 (15), pp. 10435-10440. Date of Electronic Publication: 2022 Jul 18.
Typ publikacji:
Journal Article
MeSH Terms:
Amides*
Quinolines*
Aldehydes ; Amines ; Oxides
Czasopismo naukowe
Szczegóły
Tytuł:
Condition-Dependent Selective Synthesis of Indolo[1,2- c ]quinazolines and Indolo[3,2- c ]quinolines from 2-(1 H -Indol-2-yl)anilines and Sulfoxonium Ylides.
Autorzy:
Chen G; School of Environment, School of Chemistry and Chemical Engineering, Key Laboratory for Yellow River and Huai River Water Environmental Pollution Control, Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, NMPA Key Laboratory for Research and Evaluation of Innovative Drug, Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, Henan Normal University, Xinxiang, Henan 453007, China.
Cai X; School of Environment, School of Chemistry and Chemical Engineering, Key Laboratory for Yellow River and Huai River Water Environmental Pollution Control, Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, NMPA Key Laboratory for Research and Evaluation of Innovative Drug, Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, Henan Normal University, Xinxiang, Henan 453007, China.
Zhang X; School of Environment, School of Chemistry and Chemical Engineering, Key Laboratory for Yellow River and Huai River Water Environmental Pollution Control, Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, NMPA Key Laboratory for Research and Evaluation of Innovative Drug, Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, Henan Normal University, Xinxiang, Henan 453007, China.
Fan X; School of Environment, School of Chemistry and Chemical Engineering, Key Laboratory for Yellow River and Huai River Water Environmental Pollution Control, Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, NMPA Key Laboratory for Research and Evaluation of Innovative Drug, Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, Henan Normal University, Xinxiang, Henan 453007, China.
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Źródło:
The Journal of organic chemistry [J Org Chem] 2022 Aug 05; Vol. 87 (15), pp. 9815-9828. Date of Electronic Publication: 2022 Jul 15.
Typ publikacji:
Journal Article
MeSH Terms:
Quinolines*/chemistry
Aniline Compounds ; Quinazolines
Czasopismo naukowe
Szczegóły
Tytuł:
DABCO-Promoted Cyclization of 2-Amino-4 H -chromen-4-ones with 2,6-Dibenzylidenecyclohexan-1-ones for the Synthesis of Chromeno[2,3- b ]tetrahydroquinoline.
Autorzy:
Xue Y; School of Chemistry and Chemical Engineering, Yangzhou University, 180 Siwangting Street, Yangzhou 225002, P. R. China.
Gan J; School of Chemistry and Chemical Engineering, Yangzhou University, 180 Siwangting Street, Yangzhou 225002, P. R. China.
Luo N; School of Chemistry and Chemical Engineering, Yangzhou University, 180 Siwangting Street, Yangzhou 225002, P. R. China.
Wang C; School of Chemistry and Chemical Engineering, Yangzhou University, 180 Siwangting Street, Yangzhou 225002, P. R. China.
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Źródło:
The Journal of organic chemistry [J Org Chem] 2022 Aug 05; Vol. 87 (15), pp. 10422-10429. Date of Electronic Publication: 2022 Jul 12.
Typ publikacji:
Journal Article
MeSH Terms:
Quinolines*/chemistry
Cyclization ; Piperazines/chemistry
Czasopismo naukowe
Szczegóły
Tytuł:
Preparation of Chromeno[ b ]quinoline Derivatives and Their Application for Lipid Droplets Markers.
Autorzy:
Zhu MS; College of Chemistry, Chemical Engineering and Material Science, Soochow University, No. 199 Ren'Ai Road, Suzhou 215123, China.
Zhang XQ; State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection and Collaborative Innovation Centre of Radiation Medicine of Jiangsu Higher Education Institutions, Soochow University, No. 199 Ren'Ai Road, Suzhou 215123, China.
Wang YN; College of Chemistry, Chemical Engineering and Material Science, Soochow University, No. 199 Ren'Ai Road, Suzhou 215123, China.
Xu YJ; State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection and Collaborative Innovation Centre of Radiation Medicine of Jiangsu Higher Education Institutions, Soochow University, No. 199 Ren'Ai Road, Suzhou 215123, China.
Sun R; College of Chemistry, Chemical Engineering and Material Science, Soochow University, No. 199 Ren'Ai Road, Suzhou 215123, China.
Ge JF; College of Chemistry, Chemical Engineering and Material Science, Soochow University, No. 199 Ren'Ai Road, Suzhou 215123, China.
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Źródło:
The Journal of organic chemistry [J Org Chem] 2022 Aug 05; Vol. 87 (15), pp. 10385-10389. Date of Electronic Publication: 2022 Jul 08.
Typ publikacji:
Journal Article
MeSH Terms:
Lipid Droplets*
Quinolines*
Amines ; Coumarins ; Fluorescent Dyes
Czasopismo naukowe
Szczegóły
Tytuł:
Design and synthesis of new quinoline derivatives as selective C-RAF kinase inhibitors with potent anticancer activity.
Autorzy:
Zaraei SO; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, 27272, United Arab Emirates.
Al-Ach NN; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, 27272, United Arab Emirates.
Anbar HS; Department of Clinical Pharmacy and Pharmacotherapeutics, Dubai Pharmacy College for Girls, Dubai, 19099, United Arab Emirates.
El-Gamal R; Department of Medical Biochemistry, Faculty of Medicine, Mansoura University, Mansoura, 35516, Egypt.
Tarazi H; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, 27272, United Arab Emirates; Department of Medicinal Chemistry, College of Pharmacy, University of Sharjah, Sharjah, 27272, United Arab Emirates.
Tokatly RT; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, 27272, United Arab Emirates.
Kalla RR; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, 27272, United Arab Emirates.
Munther MA; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, 27272, United Arab Emirates.
Wahba MM; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, 27272, United Arab Emirates.
Alshihabi AM; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, 27272, United Arab Emirates.
Shehata MK; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, 27272, United Arab Emirates.
Sbenati RM; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, 27272, United Arab Emirates.
Shahin AI; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, 27272, United Arab Emirates.
El-Awady R; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, 27272, United Arab Emirates; Department of Pharmacy Practice and Pharmacotherapeutics, College of Pharmacy, University of Sharjah, Sharjah, 27272, United Arab Emirates.
Al-Tel TH; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, 27272, United Arab Emirates; Department of Medicinal Chemistry, College of Pharmacy, University of Sharjah, Sharjah, 27272, United Arab Emirates.
El-Gamal MI; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, 27272, United Arab Emirates; Department of Medicinal Chemistry, College of Pharmacy, University of Sharjah, Sharjah, 27272, United Arab Emirates; Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, 35516, Egypt. Electronic address: .
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Źródło:
European journal of medicinal chemistry [Eur J Med Chem] 2022 Aug 05; Vol. 238, pp. 114434. Date of Electronic Publication: 2022 May 05.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents*/chemistry
Hydroxyquinolines*/pharmacology
Quinolines*/chemistry
Caco-2 Cells ; Cell Line, Tumor ; Cell Proliferation ; Dose-Response Relationship, Drug ; Drug Design ; Drug Screening Assays, Antitumor ; Humans ; Molecular Structure ; Protein Kinase Inhibitors/chemistry ; Proto-Oncogene Proteins c-raf/pharmacology ; Sorafenib/pharmacology ; Structure-Activity Relationship
Czasopismo naukowe
Szczegóły
Tytuł:
Antibiotic treatment targeting gram negative bacteria prevents neratinib-induced diarrhea in rats.
Autorzy:
Secombe KR; School of Biomedicine, University of Adelaide, Adelaide, South Australia, Australia. Electronic address: .
Ball IA; School of Biomedicine, University of Adelaide, Adelaide, South Australia, Australia.
Wignall AD; Division of Health Sciences, University of South Australia, South Australia, Australia.
Bateman E; School of Biomedicine, University of Adelaide, Adelaide, South Australia, Australia.
Keefe DM; School of Biomedicine, University of Adelaide, Adelaide, South Australia, Australia.
Bowen JM; School of Biomedicine, University of Adelaide, Adelaide, South Australia, Australia.
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Źródło:
Neoplasia (New York, N.Y.) [Neoplasia] 2022 Aug; Vol. 30, pp. 100806. Date of Electronic Publication: 2022 May 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Breast Neoplasms*/pathology
Quinolines*/pharmacology
Animals ; Anti-Bacterial Agents/adverse effects ; Diarrhea/chemically induced ; Diarrhea/drug therapy ; Diarrhea/prevention & control ; Female ; Gram-Negative Bacteria ; Humans ; Neomycin/adverse effects ; Rats ; Receptor, ErbB-2 ; Vancomycin/adverse effects
Czasopismo naukowe
Szczegóły
Tytuł:
The Pharmacologically Active Alkaloid Cryptolepine Activates a Type 1 Interferon Response That Is Independent of MAVS and STING Pathways.
Autorzy:
Domfeh SA; West African Centre for Cell Biology of Infectious Pathogens, University of Ghana, Legon, Ghana.; Department of Biochemistry, Cell and Molecular Biology, School of Biological Sciences University of Ghana, Legon, Ghana.; Department of Biochemistry and Biotechnology, College of Science, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Narkwa PW; Department of Clinical Microbiology, School of Medicine and Dentistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Quaye O; West African Centre for Cell Biology of Infectious Pathogens, University of Ghana, Legon, Ghana.; Department of Biochemistry, Cell and Molecular Biology, School of Biological Sciences University of Ghana, Legon, Ghana.
Kusi KA; West African Centre for Cell Biology of Infectious Pathogens, University of Ghana, Legon, Ghana.; Department of Biochemistry, Cell and Molecular Biology, School of Biological Sciences University of Ghana, Legon, Ghana.; Department of Immunology, Noguchi Memorial Institute for Medical Research, College of Health Sciences, University of Ghana, Legon, Ghana.
Addy BS; Department of Biochemistry and Biotechnology, College of Science, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Lant S; Department of Microbial Sciences, University of Surrey, Guildford, UK.
Sumner RP; Department of Microbial Sciences, University of Surrey, Guildford, UK.
Maluquer de Motes C; Department of Microbial Sciences, University of Surrey, Guildford, UK.
Awandare GA; West African Centre for Cell Biology of Infectious Pathogens, University of Ghana, Legon, Ghana.; Department of Biochemistry, Cell and Molecular Biology, School of Biological Sciences University of Ghana, Legon, Ghana.
Ansah C; Department of Pharmacology, Faculty of Pharmacy and Pharmaceutical Sciences, College of Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Mutocheluh M; Department of Clinical Microbiology, School of Medicine and Dentistry, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
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Źródło:
Journal of immunology research [J Immunol Res] 2022 Jul 26; Vol. 2022, pp. 8873536. Date of Electronic Publication: 2022 Jul 26 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
Alkaloids*/pharmacology
Antineoplastic Agents*
Interferon Type I*
Quinolines*/pharmacology
Humans ; Indole Alkaloids/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Nitrogen-Doped Carbon Supported Nanocobalt Catalyst for Hydrogen-Transfer Dearomative Coupling of Quinolinium Salts and Tetrahydroquinolines.
Autorzy:
Xu S; School of Biotechnology and Health Sciences, Wuyi University, Jiangmen 529020, China.
Cai Z; School of Biotechnology and Health Sciences, Wuyi University, Jiangmen 529020, China.
Liao C; School of Biotechnology and Health Sciences, Wuyi University, Jiangmen 529020, China.
Shi J; School of Biotechnology and Health Sciences, Wuyi University, Jiangmen 529020, China.
Wen T; School of Biotechnology and Health Sciences, Wuyi University, Jiangmen 529020, China.
Xie F; School of Biotechnology and Health Sciences, Wuyi University, Jiangmen 529020, China.
Zhu Z; School of Biotechnology and Health Sciences, Wuyi University, Jiangmen 529020, China.
Chen X; School of Biotechnology and Health Sciences, Wuyi University, Jiangmen 529020, China.
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Źródło:
Organic letters [Org Lett] 2022 Jul 22; Vol. 24 (28), pp. 5209-5213. Date of Electronic Publication: 2022 Jul 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carbon*
Quinolines*
Hydrogen ; Nitrogen ; Salts
Czasopismo naukowe
Szczegóły
Tytuł:
Diastereoselective intramolecular cyclization/Povarov reaction cascade for the one-pot synthesis of polycyclic quinolines.
Autorzy:
Kuznetsova EA; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Arbuzova str., 8, Kazan, Russian Federation. .
Smolobochkin AV; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Arbuzova str., 8, Kazan, Russian Federation. .
Rizbayeva TS; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Arbuzova str., 8, Kazan, Russian Federation. .
Gazizov AS; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Arbuzova str., 8, Kazan, Russian Federation. .
Voronina JK; N.S. Kurnakov Institute of General and Inorganic Chemistry, Russian Academy of Sciences, Leninsky Ave. 31, 119991 Moscow, Russian Federation.; G.V. Plekhanov Russian University of Economics, Stremyanny Per. 36, 117997 Moscow, Russian Federation.
Lodochnikova OA; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Arbuzova str., 8, Kazan, Russian Federation. .
Gerasimova DP; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Arbuzova str., 8, Kazan, Russian Federation. .
Dobrynin AB; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Arbuzova str., 8, Kazan, Russian Federation. .
Syakaev VV; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Arbuzova str., 8, Kazan, Russian Federation. .
Shurpik DN; Organic Chemistry Department of Kazan Federal University, Kremlevskaya, 18, 420008 Kazan, Russian Federation.
Stoikov II; Organic Chemistry Department of Kazan Federal University, Kremlevskaya, 18, 420008 Kazan, Russian Federation.
Burilov AR; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Arbuzova str., 8, Kazan, Russian Federation. .
Pudovik MA; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Arbuzova str., 8, Kazan, Russian Federation. .
Sinyashin OG; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Arbuzova str., 8, Kazan, Russian Federation. .
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Źródło:
Organic & biomolecular chemistry [Org Biomol Chem] 2022 Jul 20; Vol. 20 (28), pp. 5515-5519. Date of Electronic Publication: 2022 Jul 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Alkaloids*/chemistry
Quinolines*/chemistry
Cyclization ; Stereoisomerism
Czasopismo naukowe
Szczegóły
Wyświetlanie 1-20 z 16405

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