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Tytuł :
Health risks associated with sulfonamide and quinolone residues in cultured Chinese mitten crab (Eriocheir sinensis) in China.
Autorzy :
Fang L; Freshwater Fisheries Research Center, Chinese Academy of Fishery Sciences, Wuxi 214081, PR China; Laboratory of Quality & Safety Risk Assessment for Aquatic Products on Environmental Factors (Wuxi), Ministry of Agriculture and Rural Affairs, Wuxi 214081, PR China; Key Laboratory of Control of Quality and Safety for Aquatic Products, Ministry of Agriculture and Rural Affairs, Beijing 100000, PR China.
Huang Z; Freshwater Fisheries Research Center, Chinese Academy of Fishery Sciences, Wuxi 214081, PR China; Laboratory of Quality & Safety Risk Assessment for Aquatic Products on Environmental Factors (Wuxi), Ministry of Agriculture and Rural Affairs, Wuxi 214081, PR China; Key Laboratory of Control of Quality and Safety for Aquatic Products, Ministry of Agriculture and Rural Affairs, Beijing 100000, PR China; Wuxi Fisheries College, Nanjing Agricultural University, Wuxi 214081, PR China.
Fan L; Freshwater Fisheries Research Center, Chinese Academy of Fishery Sciences, Wuxi 214081, PR China; Laboratory of Quality & Safety Risk Assessment for Aquatic Products on Environmental Factors (Wuxi), Ministry of Agriculture and Rural Affairs, Wuxi 214081, PR China; Key Laboratory of Control of Quality and Safety for Aquatic Products, Ministry of Agriculture and Rural Affairs, Beijing 100000, PR China; Wuxi Fisheries College, Nanjing Agricultural University, Wuxi 214081, PR China.
Hu G; Freshwater Fisheries Research Center, Chinese Academy of Fishery Sciences, Wuxi 214081, PR China; Laboratory of Quality & Safety Risk Assessment for Aquatic Products on Environmental Factors (Wuxi), Ministry of Agriculture and Rural Affairs, Wuxi 214081, PR China; Key Laboratory of Control of Quality and Safety for Aquatic Products, Ministry of Agriculture and Rural Affairs, Beijing 100000, PR China; Wuxi Fisheries College, Nanjing Agricultural University, Wuxi 214081, PR China.
Qiu L; Freshwater Fisheries Research Center, Chinese Academy of Fishery Sciences, Wuxi 214081, PR China; Laboratory of Quality & Safety Risk Assessment for Aquatic Products on Environmental Factors (Wuxi), Ministry of Agriculture and Rural Affairs, Wuxi 214081, PR China; Key Laboratory of Control of Quality and Safety for Aquatic Products, Ministry of Agriculture and Rural Affairs, Beijing 100000, PR China; Wuxi Fisheries College, Nanjing Agricultural University, Wuxi 214081, PR China.
Song C; Freshwater Fisheries Research Center, Chinese Academy of Fishery Sciences, Wuxi 214081, PR China; Laboratory of Quality & Safety Risk Assessment for Aquatic Products on Environmental Factors (Wuxi), Ministry of Agriculture and Rural Affairs, Wuxi 214081, PR China; Key Laboratory of Control of Quality and Safety for Aquatic Products, Ministry of Agriculture and Rural Affairs, Beijing 100000, PR China; Wuxi Fisheries College, Nanjing Agricultural University, Wuxi 214081, PR China. Electronic address: .
Chen J; Freshwater Fisheries Research Center, Chinese Academy of Fishery Sciences, Wuxi 214081, PR China; Laboratory of Quality & Safety Risk Assessment for Aquatic Products on Environmental Factors (Wuxi), Ministry of Agriculture and Rural Affairs, Wuxi 214081, PR China; Key Laboratory of Control of Quality and Safety for Aquatic Products, Ministry of Agriculture and Rural Affairs, Beijing 100000, PR China; Wuxi Fisheries College, Nanjing Agricultural University, Wuxi 214081, PR China. Electronic address: .
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Źródło :
Marine pollution bulletin [Mar Pollut Bull] 2021 Apr; Vol. 165, pp. 112184. Date of Electronic Publication: 2021 Feb 20.
Typ publikacji :
Journal Article
MeSH Terms :
Brachyura*
Quinolones*
Animals ; China ; Sulfanilamide ; Sulfonamides
Czasopismo naukowe
Tytuł :
Synthesis of 3,4-dihydroquinolin-2(1H)-one derivatives with anticonvulsant activity and their binding to the GABA A receptor.
Autorzy :
Wang S; College of Pharmacy, Liaocheng University, Liaocheng, Shandong 252059, China. Electronic address: .
Liu H; College of Life Sciences, Liaocheng University, Liaocheng, Shandong 252059, China.
Lei K; College of Pharmacy, Liaocheng University, Liaocheng, Shandong 252059, China.
Li G; College of Pharmacy, Liaocheng University, Liaocheng, Shandong 252059, China.
Li J; College of Pharmacy, Liaocheng University, Liaocheng, Shandong 252059, China.
Wei Y; College of Pharmacy, Liaocheng University, Liaocheng, Shandong 252059, China.
Wang X; College of Pharmacy, Liaocheng University, Liaocheng, Shandong 252059, China.
Liu R; College of Pharmacy, Liaocheng University, Liaocheng, Shandong 252059, China.
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Źródło :
Bioorganic chemistry [Bioorg Chem] 2020 Oct; Vol. 103, pp. 104182. Date of Electronic Publication: 2020 Aug 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anticonvulsants/*therapeutic use
Epilepsy/*drug therapy
Quinolones/*therapeutic use
Receptors, GABA-A/*metabolism
Animals ; Anticonvulsants/chemical synthesis ; Anticonvulsants/metabolism ; Anticonvulsants/pharmacokinetics ; Drug Design ; Electroshock ; Epilepsy/chemically induced ; Mice ; Molecular Docking Simulation ; Molecular Structure ; Pentylenetetrazole ; Quinolones/chemical synthesis ; Quinolones/metabolism ; Quinolones/pharmacokinetics ; Rats, Wistar ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Investigating the impact of hospital antibiotic usage on aquatic environment and aquaculture systems: A molecular study of quinolone resistance in Escherichia coli.
Autorzy :
Girijan SK; Department of Aquatic Animal Health Management, Kerala University of Fisheries and Ocean Studies, Kochi, Kerala, India.
Paul R; State Laboratory for Livestock, Marine & Agri Products (SLMAP), Department of Animal Husbandry, Government of Kerala, India.
V J RK; Department of Aquatic Animal Health Management, Kerala University of Fisheries and Ocean Studies, Kochi, Kerala, India; Department of Aquaculture, Kerala University of Fisheries and Ocean Studies, Kochi, Kerala, India.
Pillai D; Department of Aquatic Animal Health Management, Kerala University of Fisheries and Ocean Studies, Kochi, Kerala, India. Electronic address: .
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Źródło :
The Science of the total environment [Sci Total Environ] 2020 Dec 15; Vol. 748, pp. 141538. Date of Electronic Publication: 2020 Aug 06.
Typ publikacji :
Journal Article
MeSH Terms :
Escherichia coli*/genetics
Quinolones*
Anti-Bacterial Agents/pharmacology ; Aquaculture ; Drug Resistance, Bacterial/genetics ; Humans ; India ; Microbial Sensitivity Tests ; Plasmids
Czasopismo naukowe
Tytuł :
Cost-Effectiveness of Ivacaftor Therapy for Treatment of Cystic Fibrosis Patients With the G551D Gating Mutation.
Autorzy :
Wherry K; Division of Health Policy and Management, University of Minnesota, School of Public Health, Minneapolis, MN, USA. Electronic address: .
Williamson I; Division of Health Policy and Management, University of Minnesota, School of Public Health, Minneapolis, MN, USA.
Chapman RH; Institute for Clinical and Economic Review, Boston, MA, USA.
Kuntz KM; Division of Health Policy and Management, University of Minnesota, School of Public Health, Minneapolis, MN, USA.
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Źródło :
Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research [Value Health] 2020 Oct; Vol. 23 (10), pp. 1332-1339. Date of Electronic Publication: 2020 Aug 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Aminophenols/*therapeutic use
Chloride Channel Agonists/*therapeutic use
Cystic Fibrosis/*economics
Health Care Costs/*statistics & numerical data
Quinolones/*therapeutic use
Aminophenols/economics ; Chloride Channel Agonists/economics ; Cost-Benefit Analysis ; Cystic Fibrosis/drug therapy ; Cystic Fibrosis/genetics ; Drug Costs ; Female ; Humans ; Male ; Mutation/genetics ; Quality-Adjusted Life Years ; Quinolones/economics ; Time Factors
Czasopismo naukowe
Tytuł :
Alkaloids from the nearly ripe fruits of Evodia rutaecarpa and their bioactivities.
Autorzy :
Li DW; The First Affiliated Hospital of Dalian Medical University, No.222 Zhongshan Road, Dalian 116011, China.
Zhang M; The First Affiliated Hospital of Dalian Medical University, No.222 Zhongshan Road, Dalian 116011, China; College of Pharmacy, Academy of Integrative Medicine, The National & Local Joint Engineering Research Center for Drug Development of Neurodegenerative Disease, Dalian Medical University, Dalian 116044, China.
Feng L; College of Pharmacy, Academy of Integrative Medicine, The National & Local Joint Engineering Research Center for Drug Development of Neurodegenerative Disease, Dalian Medical University, Dalian 116044, China.
Huang SS; College of Pharmacy, Academy of Integrative Medicine, The National & Local Joint Engineering Research Center for Drug Development of Neurodegenerative Disease, Dalian Medical University, Dalian 116044, China.
Zhang BJ; College of Pharmacy, Academy of Integrative Medicine, The National & Local Joint Engineering Research Center for Drug Development of Neurodegenerative Disease, Dalian Medical University, Dalian 116044, China.
Liu SS; The First Affiliated Hospital of Dalian Medical University, No.222 Zhongshan Road, Dalian 116011, China.
Deng S; College of Pharmacy, Academy of Integrative Medicine, The National & Local Joint Engineering Research Center for Drug Development of Neurodegenerative Disease, Dalian Medical University, Dalian 116044, China.
Wang C; College of Pharmacy, Academy of Integrative Medicine, The National & Local Joint Engineering Research Center for Drug Development of Neurodegenerative Disease, Dalian Medical University, Dalian 116044, China. Electronic address: .
Ma XC; College of Pharmacy, Academy of Integrative Medicine, The National & Local Joint Engineering Research Center for Drug Development of Neurodegenerative Disease, Dalian Medical University, Dalian 116044, China; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou 221004, China. Electronic address: .
Leng AJ; The First Affiliated Hospital of Dalian Medical University, No.222 Zhongshan Road, Dalian 116011, China. Electronic address: .
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Źródło :
Fitoterapia [Fitoterapia] 2020 Oct; Vol. 146, pp. 104668. Date of Electronic Publication: 2020 Jun 12.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Bacterial Agents/*pharmacology
Antineoplastic Agents, Phytogenic/*pharmacology
Evodia/*chemistry
Fruit/*chemistry
Indole Alkaloids/*pharmacology
Quinolones/*pharmacology
Anti-Bacterial Agents/isolation & purification ; Antineoplastic Agents, Phytogenic/isolation & purification ; Bacillus cereus/drug effects ; Cell Line, Tumor ; China ; Humans ; Indole Alkaloids/isolation & purification ; Molecular Structure ; Phytochemicals/isolation & purification ; Phytochemicals/pharmacology ; Quinolones/isolation & purification
Czasopismo naukowe
Tytuł :
Ivacaftor improves lung disease in patients with advanced CF carrying CFTR mutations that confer residual function.
Autorzy :
Salvatore D; Cystic Fibrosis Center, AOR Ospedale San Carlo, Potenza, Italy. Electronic address: .
Terlizzi V; Cystic Fibrosis Center, Department of Pediatric Medicine, Anna Meyer Children's Hospital, Florence, Italy.
Francalanci M; Cystic Fibrosis Center, Department of Pediatric Medicine, Anna Meyer Children's Hospital, Florence, Italy.
Taccetti G; Cystic Fibrosis Center, Department of Pediatric Medicine, Anna Meyer Children's Hospital, Florence, Italy.
Messore B; Adult Cystic Fibrosis Center, Azienda Ospedaliera Universitaria San Luigi Gonzaga, Orbassano, Italy.
Biglia C; Adult Cystic Fibrosis Center, Azienda Ospedaliera Universitaria San Luigi Gonzaga, Orbassano, Italy.
Pisi G; Cystic Fibrosis Unit, Department of Pediatrics, University Hospital, Parma, Italy.
Calderazzo MA; Cystic Fibrosis Center, Hospital Giovanni Paolo II, Lamezia Terme, Italy.
Caloiero M; Cystic Fibrosis Center, Hospital Giovanni Paolo II, Lamezia Terme, Italy.
Pizzamiglio G; Cystic Fibrosis Center - Adult Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.
Majo F; Cystic Fibrosis Unit, Bambino Gesù Children's Hospital, Rome, Italy.
Cresta F; Cystic Fibrosis Center, IRCCS G. Gaslini Institute, Genoa, Italy.
Leonetti G; Cystic Fibrosis Regional Center, Department of Biomedical and Human Oncology, Pediatrics Section, U.O. 'B. Trambusti', Policlinico, University of Bari, Bari, Italy.
De Venuto D; Cystic Fibrosis Regional Center, Department of Biomedical and Human Oncology, Pediatrics Section, U.O. 'B. Trambusti', Policlinico, University of Bari, Bari, Italy.
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Źródło :
Respiratory medicine [Respir Med] 2020 Sep; Vol. 171, pp. 106073. Date of Electronic Publication: 2020 Jul 03.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Mutation*
Respiratory Function Tests*
Aminophenols/*therapeutic use
Cystic Fibrosis/*drug therapy
Cystic Fibrosis/*physiopathology
Lung/*physiopathology
Lung Diseases/*drug therapy
Lung Diseases/*etiology
Quinolones/*therapeutic use
Adult ; Aminophenols/pharmacology ; Cystic Fibrosis/complications ; Cystic Fibrosis/genetics ; Cystic Fibrosis Transmembrane Conductance Regulator/genetics ; Female ; Humans ; Lung Diseases/physiopathology ; Male ; Middle Aged ; Quinolones/pharmacology ; Retrospective Studies ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Tytuł :
Room-temperature synthesis of flower-shaped covalent organic frameworks for solid-phase extraction of quinolone antibiotics.
Autorzy :
Xu G; Qilu University of Technology (Shandong Academy of Sciences), Shandong Analysis and Test Center, Key Laboratory for Applied Technology of Sophisticated Analytical Instruments of Shandong Province, Jinan, 250014, China.
Dong X; Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China.
Hou L; College of Food Science and Engineering, Shandong Agricultural University, Taian, 271018, China.
Wang X; Qilu University of Technology (Shandong Academy of Sciences), Shandong Analysis and Test Center, Key Laboratory for Applied Technology of Sophisticated Analytical Instruments of Shandong Province, Jinan, 250014, China.
Liu L; Qilu University of Technology (Shandong Academy of Sciences), Shandong Analysis and Test Center, Key Laboratory for Applied Technology of Sophisticated Analytical Instruments of Shandong Province, Jinan, 250014, China.
Ma H; Qilu University of Technology (Shandong Academy of Sciences), Shandong Analysis and Test Center, Key Laboratory for Applied Technology of Sophisticated Analytical Instruments of Shandong Province, Jinan, 250014, China.
Zhao RS; Qilu University of Technology (Shandong Academy of Sciences), Shandong Analysis and Test Center, Key Laboratory for Applied Technology of Sophisticated Analytical Instruments of Shandong Province, Jinan, 250014, China. Electronic address: .
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Źródło :
Analytica chimica acta [Anal Chim Acta] 2020 Aug 22; Vol. 1126, pp. 82-90. Date of Electronic Publication: 2020 Jun 11.
Typ publikacji :
Journal Article
MeSH Terms :
Metal-Organic Frameworks*
Quinolones*
Animals ; Anti-Bacterial Agents ; Chromatography, High Pressure Liquid ; Limit of Detection ; Reproducibility of Results ; Solid Phase Extraction ; Temperature
Czasopismo naukowe
Tytuł :
Identification of N-acyl quinolin-2(1H)-ones as new selective agents against clinical isolates of Acanthamoeba keratitis.
Autorzy :
Reyes-Batlle M; Instituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias, Laboratorio de Quimioterapias de Protozoos, Universidad de La Laguna, Tenerife, Spain.
Freijo MB; Instituto Universitario de Bio-Orgánica 'Antonio González', Departamento de Química Orgánica, Universidad de La Laguna, Avda. Astrofísico Fco. Sánchez 2, 38206 La Laguna, Tenerife, Spain.
López-Arencibia A; Instituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias, Laboratorio de Quimioterapias de Protozoos, Universidad de La Laguna, Tenerife, Spain; Departamento de Obstetricia, Ginecología, Pediatría, Medicina Preventiva y Salud Pública, Toxicología, Medicina Legal y Forense y Parasitología, Universidad de La Laguna, Spain.
Lorenzo-Morales J; Instituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias, Laboratorio de Quimioterapias de Protozoos, Universidad de La Laguna, Tenerife, Spain; Departamento de Obstetricia, Ginecología, Pediatría, Medicina Preventiva y Salud Pública, Toxicología, Medicina Legal y Forense y Parasitología, Universidad de La Laguna, Spain.
McNaughton-Smith G; Centro Atlántico del Medicamento S.A (CEAMED S.A.), PCTT, La Laguna, Tenerife, Spain.
Piñero JE; Instituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias, Laboratorio de Quimioterapias de Protozoos, Universidad de La Laguna, Tenerife, Spain; Departamento de Obstetricia, Ginecología, Pediatría, Medicina Preventiva y Salud Pública, Toxicología, Medicina Legal y Forense y Parasitología, Universidad de La Laguna, Spain. Electronic address: .
Abad-Grillo T; Instituto Universitario de Bio-Orgánica 'Antonio González', Departamento de Química Orgánica, Universidad de La Laguna, Avda. Astrofísico Fco. Sánchez 2, 38206 La Laguna, Tenerife, Spain. Electronic address: .
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Źródło :
Bioorganic chemistry [Bioorg Chem] 2020 Jun; Vol. 99, pp. 103791. Date of Electronic Publication: 2020 Mar 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Acanthamoeba/*drug effects
Acanthamoeba Keratitis/*drug therapy
Antiprotozoal Agents/*pharmacology
Leishmania/*drug effects
Quinolones/*pharmacology
Trypanosoma/*drug effects
Acanthamoeba/isolation & purification ; Antiprotozoal Agents/chemical synthesis ; Antiprotozoal Agents/chemistry ; Apoptosis/drug effects ; Cell Death/drug effects ; Dose-Response Relationship, Drug ; Leishmania/isolation & purification ; Molecular Structure ; Parasitic Sensitivity Tests ; Quinolones/chemical synthesis ; Quinolones/chemistry ; Structure-Activity Relationship ; Trypanosoma/isolation & purification
Czasopismo naukowe
Tytuł :
Efficacy and Safety of Brexpiprazole for the Treatment of Agitation in Alzheimer's Dementia: Two 12-Week, Randomized, Double-Blind, Placebo-Controlled Trials.
Autorzy :
Grossberg GT; St. Louis University School of Medicine (GTG), St. Louis, MO. Electronic address: .
Kohegyi E; Otsuka Pharmaceutical Development & Commercialization Inc., (EK, VM, MH, MS, RAB, RDM) Princeton, NJ.
Mergel V; Otsuka Pharmaceutical Development & Commercialization Inc., (EK, VM, MH, MS, RAB, RDM) Princeton, NJ.
Josiassen MK; H. Lundbeck A/S (MKJ, DM), Copenhagen, Denmark.
Meulien D; H. Lundbeck A/S (MKJ, DM), Copenhagen, Denmark.
Hobart M; Otsuka Pharmaceutical Development & Commercialization Inc., (EK, VM, MH, MS, RAB, RDM) Princeton, NJ.
Slomkowski M; Otsuka Pharmaceutical Development & Commercialization Inc., (EK, VM, MH, MS, RAB, RDM) Princeton, NJ.
Baker RA; Otsuka Pharmaceutical Development & Commercialization Inc., (EK, VM, MH, MS, RAB, RDM) Princeton, NJ.
McQuade RD; Otsuka Pharmaceutical Development & Commercialization Inc., (EK, VM, MH, MS, RAB, RDM) Princeton, NJ.
Cummings JL; Department of Brain Health, School of Integrated Health Sciences, University of Nevada Las Vegas (UNLV) (JLC), Las Vegas, NV; Cleveland Clinic Lou Ruvo Center for Brain Health (JLC), Las Vegas, NV.
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Źródło :
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry [Am J Geriatr Psychiatry] 2020 Apr; Vol. 28 (4), pp. 383-400. Date of Electronic Publication: 2019 Oct 01.
Typ publikacji :
Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Alzheimer Disease/*drug therapy
Psychomotor Agitation/*drug therapy
Quinolones/*administration & dosage
Thiophenes/*administration & dosage
Aged ; Aged, 80 and over ; Alzheimer Disease/diagnosis ; Female ; Headache/etiology ; Humans ; Internationality ; Male ; Middle Aged ; Psychiatric Status Rating Scales ; Psychomotor Agitation/diagnosis ; Quinolones/adverse effects ; Sleep Initiation and Maintenance Disorders/etiology ; Thiophenes/adverse effects ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Molecular mechanisms of apoptosis induced by a novel synthetic quinolinone derivative in HL-60 human leukemia cells.
Autorzy :
Drogosz-Stachowicz J; Department of Biomolecular Chemistry, Medical University of Łódź, 92-215, Łódź, Poland.
Długosz-Pokorska A; Department of Biomolecular Chemistry, Medical University of Łódź, 92-215, Łódź, Poland.
Gach-Janczak K; Department of Biomolecular Chemistry, Medical University of Łódź, 92-215, Łódź, Poland.
Jaskulska A; Institute of Organic Chemistry, Łódź University of Technology, 90-924, Łódź, Poland.
Janecki T; Institute of Organic Chemistry, Łódź University of Technology, 90-924, Łódź, Poland.
Janecka A; Department of Biomolecular Chemistry, Medical University of Łódź, 92-215, Łódź, Poland. Electronic address: .
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Źródło :
Chemico-biological interactions [Chem Biol Interact] 2020 Apr 01; Vol. 320, pp. 109005. Date of Electronic Publication: 2020 Feb 25.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis/*drug effects
Quinolones/*pharmacology
Caspases/genetics ; Caspases/metabolism ; Cell Cycle/drug effects ; Cell Proliferation ; DNA Damage/drug effects ; Gene Expression Regulation, Neoplastic/drug effects ; HL-60 Cells ; Humans ; Membrane Potential, Mitochondrial/drug effects ; Molecular Structure ; Quinolones/chemistry ; Reactive Oxygen Species ; Real-Time Polymerase Chain Reaction ; fas Receptor/genetics ; fas Receptor/metabolism
Czasopismo naukowe
Tytuł :
Are We Getting Better at Managing Agitation in Dementia?
Autorzy :
Almeida OP; WA Centre for Health and Ageing, Medical School, University of Western Australia, Perth, WA, Australia. Electronic address: .
Ford AH; WA Centre for Health and Ageing, Medical School, University of Western Australia, Perth, WA, Australia.
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Źródło :
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry [Am J Geriatr Psychiatry] 2020 Apr; Vol. 28 (4), pp. 401-403. Date of Electronic Publication: 2019 Nov 15.
Typ publikacji :
Editorial; Comment
MeSH Terms :
Alzheimer Disease*
Dementia*
Quinolones*
Double-Blind Method ; Humans ; Thiophenes
Opinia redakcyjna
Tytuł :
Prenylated quinolinone alkaloids and prenylated isoindolinone alkaloids from the fungus Aspergillus nidulans.
Autorzy :
Li Q; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, People's Republic of China.
Chen C; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, People's Republic of China.
He Y; Department of Pharmacy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, People's Republic of China.
Wei M; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, People's Republic of China.
Cheng L; Hubei Key Laboratory of Wudang Local Chinese Medicine Research, Hubei Engineering Technology Center for Comprehensive Utilization of Medicinal Plants, College of Pharmacy, Hubei University of Medicine, Shiyan, 442000, People's Republic of China.
Kang X; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, People's Republic of China.
Wang J; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, People's Republic of China.
Hao X; Hubei Key Laboratory of Wudang Local Chinese Medicine Research, Hubei Engineering Technology Center for Comprehensive Utilization of Medicinal Plants, College of Pharmacy, Hubei University of Medicine, Shiyan, 442000, People's Republic of China. Electronic address: .
Zhu H; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, People's Republic of China. Electronic address: .
Zhang Y; Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, People's Republic of China. Electronic address: .
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Źródło :
Phytochemistry [Phytochemistry] 2020 Jan; Vol. 169, pp. 112177. Date of Electronic Publication: 2019 Nov 08.
Typ publikacji :
Journal Article
MeSH Terms :
Alkaloids/*pharmacology
Antineoplastic Agents/*pharmacology
Aspergillus nidulans/*chemistry
Phthalimides/*pharmacology
Quinolones/*pharmacology
Alkaloids/chemistry ; Alkaloids/isolation & purification ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/isolation & purification ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Humans ; Molecular Structure ; Phthalimides/chemistry ; Phthalimides/isolation & purification ; Prenylation ; Quinolones/chemistry ; Quinolones/isolation & purification ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Recent advances in the synthetic and medicinal perspective of quinolones: A review.
Autorzy :
Dhiman P; Department of Pharmaceutical Chemistry, ISF College of Pharmacy, G.T. Road, Ghal Kalan, Moga 142001, Punjab, India.
Arora N; Department of Pharmaceutical Chemistry, ISF College of Pharmacy, G.T. Road, Ghal Kalan, Moga 142001, Punjab, India.
Thanikachalam PV; Department of Pharmaceutical Chemistry, ISF College of Pharmacy, G.T. Road, Ghal Kalan, Moga 142001, Punjab, India.
Monga V; Department of Pharmaceutical Chemistry, ISF College of Pharmacy, G.T. Road, Ghal Kalan, Moga 142001, Punjab, India. Electronic address: .
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Źródło :
Bioorganic chemistry [Bioorg Chem] 2019 Nov; Vol. 92, pp. 103291. Date of Electronic Publication: 2019 Sep 19.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Anti-Infective Agents/*pharmacology
Anti-Inflammatory Agents, Non-Steroidal/*pharmacology
Antineoplastic Agents/*pharmacology
Carbonic Anhydrase Inhibitors/*pharmacology
Quinolones/*pharmacology
Animals ; Anti-Infective Agents/chemical synthesis ; Anti-Infective Agents/chemistry ; Anti-Inflammatory Agents, Non-Steroidal/chemical synthesis ; Anti-Inflammatory Agents, Non-Steroidal/chemistry ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Carbonic Anhydrase Inhibitors/chemical synthesis ; Carbonic Anhydrase Inhibitors/chemistry ; Humans ; Molecular Structure ; Quinolones/chemical synthesis ; Quinolones/chemistry
Czasopismo naukowe
Tytuł :
Occurrence of quinotone antibiotics and their impacts on aquatic environment in typical river-estuary system of Jiaozhou Bay, China.
Autorzy :
Liu K; Key Laboratory of Marine Chemistry Theory and Technology, Ministry of Education /Institute for Advanced Ocean Study, Ocean University of China, Qingdao, 266100, China; Qingdao Institute of Marine Geology, Qingdao, 266071, China; Laboratory for Marine Ecology and Environmental Science, Qingdao National Laboratory for Marine Science and Technology, Qingdao, 266237, China.
Zhang D; Qingdao Institute of Marine Geology, Qingdao, 266071, China; Laboratory for Marine Ecology and Environmental Science, Qingdao National Laboratory for Marine Science and Technology, Qingdao, 266237, China. Electronic address: .
Xiao X; Key Laboratory of Marine Chemistry Theory and Technology, Ministry of Education /Institute for Advanced Ocean Study, Ocean University of China, Qingdao, 266100, China; Laboratory for Marine Ecology and Environmental Science, Qingdao National Laboratory for Marine Science and Technology, Qingdao, 266237, China. Electronic address: .
Cui L; Institute of Wetland Research, Chinese Academy of Forestry, Beijing, 100091, China.
Zhang H; Key Laboratory of Marine Chemistry Theory and Technology, Ministry of Education /Institute for Advanced Ocean Study, Ocean University of China, Qingdao, 266100, China; Laboratory for Marine Ecology and Environmental Science, Qingdao National Laboratory for Marine Science and Technology, Qingdao, 266237, China.
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Źródło :
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2020 Mar 01; Vol. 190, pp. 109993. Date of Electronic Publication: 2019 Dec 20.
Typ publikacji :
Journal Article
MeSH Terms :
Estuaries*
Anti-Bacterial Agents/*analysis
Quinolones/*analysis
Rivers/*chemistry
Water Pollutants, Chemical/*analysis
Anti-Bacterial Agents/toxicity ; Bays ; China ; Geologic Sediments/chemistry ; Phytoplankton/drug effects ; Plants/chemistry ; Quinolones/toxicity ; Water Pollutants, Chemical/toxicity ; Wetlands
Czasopismo naukowe
Tytuł :
Treatment-resistant schizophrenia successfully maintained with brexpiprazole following abrupt withdrawal of clozapine due to neutropenia.
Autorzy :
Okada T; Department of Psychiatry, Jichi Medical University, Tochigi, Japan. Electronic address: .
Kumakura J; Department of Psychiatry, Jichi Medical University, Tochigi, Japan.
Yasuda M; Department of Psychiatry, Jichi Medical University, Tochigi, Japan.
Suda S; Department of Psychiatry, Jichi Medical University, Tochigi, Japan.
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Źródło :
Asian journal of psychiatry [Asian J Psychiatr] 2020 Jan; Vol. 47, pp. 101836. Date of Electronic Publication: 2019 Oct 18.
Typ publikacji :
Case Reports; Letter
MeSH Terms :
Antipsychotic Agents/*adverse effects
Clozapine/*adverse effects
Neutropenia/*chemically induced
Quinolones/*pharmacology
Schizophrenia/*drug therapy
Serotonin Agents/*pharmacology
Thiophenes/*pharmacology
Adolescent ; Female ; Humans ; Quinolones/administration & dosage ; Serotonin Agents/administration & dosage ; Thiophenes/administration & dosage
Raport
Tytuł :
Injected laquinimod D-α-tocopheryl polyethylene glycol-1000 succinate polymeric micelles for the treatment of inflammatory bowel disease.
Autorzy :
Wang L; Department of Pharmaceutics, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou City, Zhejiang Province 325035, China.
Xue P; Department of Pharmaceutics, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou City, Zhejiang Province 325035, China.
Tong M; Department of Pharmaceutics, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou City, Zhejiang Province 325035, China.
Chen R; Department of Pharmaceutics, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou City, Zhejiang Province 325035, China.
Yang W; Department of Pharmaceutics, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou City, Zhejiang Province 325035, China.
ZhuGe D; Department of Pharmaceutics, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou City, Zhejiang Province 325035, China.
Yuan J; Department of Orthopaedics, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Yao Q; Department of Pharmaceutics, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou City, Zhejiang Province 325035, China.
Zhao Y; Department of Pharmaceutics, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou City, Zhejiang Province 325035, China. Electronic address: .
Xu H; Department of Pharmaceutics, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou City, Zhejiang Province 325035, China. Electronic address: .
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Źródło :
Colloids and surfaces. B, Biointerfaces [Colloids Surf B Biointerfaces] 2020 Jan 01; Vol. 185, pp. 110575. Date of Electronic Publication: 2019 Oct 19.
Typ publikacji :
Journal Article
MeSH Terms :
Injections*
Micelles*
Inflammatory Bowel Diseases/*drug therapy
Quinolones/*therapeutic use
Vitamin E/*therapeutic use
Animals ; Colon/drug effects ; Colon/pathology ; Dextran Sulfate ; Drug Liberation ; Inflammation/pathology ; Inflammatory Bowel Diseases/pathology ; Intestinal Mucosa/drug effects ; Intestinal Mucosa/pathology ; Mice, Inbred ICR ; Particle Size ; Quinolones/pharmacology ; Solubility ; Spectroscopy, Fourier Transform Infrared ; Static Electricity ; Vitamin E/pharmacology
Czasopismo naukowe
Tytuł :
An open-label extension study of ivacaftor in children with CF and a CFTR gating mutation initiating treatment at age 2-5 years (KLIMB).
Autorzy :
Rosenfeld M; Seattle Children's Hospital, 4800 Sand Point Way NE, Seattle, WA 98105, USA. Electronic address: .
Cunningham S; University of Edinburgh Centre for Inflammation Research and NHS Lothian, Edinburgh, UK. Electronic address: .
Harris WT; University of Alabama at Birmingham, 1720 2nd Avenue S, Birmingham, AL 35294, USA. Electronic address: .
Lapey A; Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA. Electronic address: .
Regelmann WE; University of Minnesota Medical School, 420 Delaware Street SE, Minneapolis, MN 55455, USA. Electronic address: .
Sawicki GS; Boston Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA. Electronic address: .
Southern KW; University of Liverpool, Liverpool L69 3BX, UK. Electronic address: .
Chilvers M; British Columbia Children's Hospital, 4480 Oak Street, Vancouver, BC V6H 3N1, Canada. Electronic address: .
Higgins M; Vertex Pharmaceuticals (Europe) Limited, 2 Kingdom Street, London, W2 6BD, UK. Electronic address: .
Tian S; Vertex Pharmaceuticals Incorporated, 50 Northern Avenue, Boston, MA 02210, USA. Electronic address: .
Cooke J; Formerly of Vertex Pharmaceuticals (Europe) Limited, 2 Kingdom Street, London W2 6BD, UK.
Davies JC; National Heart & Lung Institute, Imperial College London & Royal Brompton Hospital, London SW3 6LR, UK. Electronic address: .
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Corporate Authors :
KLIMB study group
Źródło :
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society [J Cyst Fibros] 2019 Nov; Vol. 18 (6), pp. 838-843. Date of Electronic Publication: 2019 Apr 30.
Typ publikacji :
Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Aminophenols*/administration & dosage
Aminophenols*/adverse effects
Aminophenols*/pharmacokinetics
Cystic Fibrosis*/diagnosis
Cystic Fibrosis*/drug therapy
Cystic Fibrosis*/genetics
Quinolones*/administration & dosage
Quinolones*/adverse effects
Quinolones*/pharmacokinetics
Sweat*/chemistry
Sweat*/drug effects
Cystic Fibrosis Transmembrane Conductance Regulator/*genetics
Pancreas/*enzymology
Weight Gain/*drug effects
Body Mass Index ; Child, Preschool ; Chloride Channel Agonists/administration & dosage ; Chloride Channel Agonists/adverse effects ; Chloride Channel Agonists/pharmacokinetics ; Female ; Humans ; Ion Channel Gating/genetics ; Liver Function Tests/methods ; Liver Function Tests/statistics & numerical data ; Male ; Sodium Chloride/analysis ; Transaminases/blood ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Combined effects of Pseudomonas quinolone signal-based quorum quenching and graphene oxide on the mitigation of biofouling and improvement of the application potential for the thin-film composite membrane.
Autorzy :
Li Y; State Key Laboratory of Water Environment Simulation, School of Environment, Beijing Normal University, Beijing 100875, China. Electronic address: .
Yang Y; State Key Laboratory of Water Environment Simulation, School of Environment, Beijing Normal University, Beijing 100875, China. Electronic address: .
Feng Y; State Key Laboratory of Water Environment Simulation, School of Environment, Beijing Normal University, Beijing 100875, China. Electronic address: .
Pu J; Institute for Future Initiatives, The University of Tokyo, Tokyo 113-8654, Japan. Electronic address: .
Hou LA; State Key Laboratory of Water Environment Simulation, School of Environment, Beijing Normal University, Beijing 100875, China; Xi'an High-Tech Institute, Xi'an 710025, China. Electronic address: .
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Źródło :
The Science of the total environment [Sci Total Environ] 2021 Mar 15; Vol. 760, pp. 143348. Date of Electronic Publication: 2020 Oct 29.
Typ publikacji :
Journal Article
MeSH Terms :
Biofouling*/prevention & control
Water Purification*
Graphite ; Membranes, Artificial ; Osmosis ; Quinolones ; Quorum Sensing
Czasopismo naukowe
Tytuł :
Shifts in bacterial communities and antibiotic resistance genes in surface water and gut microbiota of guppies (Poecilia reticulata) in the upper Rio Uberabinha, Brazil.
Autorzy :
Jia J; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China.
Gomes-Silva G; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China.
Plath M; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China.
Pereira BB; Institute of Geography, Department of Environmental Health, Federal University of Uberlândia, Santa Mônica Campus, Uberlândia, Minas Gerais 34.408-100, Brazil; Institute of Biotechnology, Department of Genetics and Biochemistry, Federal University of Uberlândia, Umuarama Campus, Uberlândia, Minas Gerais 34.408-100, Brazil.
UeiraVieira C; Institute of Geography, Department of Environmental Health, Federal University of Uberlândia, Santa Mônica Campus, Uberlândia, Minas Gerais 34.408-100, Brazil.
Wang Z; College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China. Electronic address: .
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Źródło :
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2021 Mar 15; Vol. 211, pp. 111955. Date of Electronic Publication: 2021 Jan 25.
Typ publikacji :
Journal Article
MeSH Terms :
Genes, Bacterial*
Drug Resistance, Microbial/*genetics
Gastrointestinal Microbiome/*drug effects
Poecilia/*physiology
Water Pollution/*statistics & numerical data
Animals ; Anti-Bacterial Agents/analysis ; Bacteria/genetics ; Brazil ; Integrons ; Microbiota/genetics ; Poecilia/genetics ; Poecilia/microbiology ; Quinolones/analysis ; RNA, Ribosomal, 16S/genetics ; Rivers/microbiology ; Water/analysis ; Water Pollution/analysis
Czasopismo naukowe
Tytuł :
Efficacy and safety of the elexacaftor plus tezacaftor plus ivacaftor combination regimen in people with cystic fibrosis homozygous for the F508del mutation: a double-blind, randomised, phase 3 trial.
Autorzy :
Heijerman HGM; Department of Pulmonology, University Medical Center Utrecht, Utrecht, Netherlands. Electronic address: .
McKone EF; St Vincent's University Hospital and University College Dublin School of Medicine, Dublin, Ireland.
Downey DG; Centre for Experimental Medicine, Queen's University Belfast, Belfast, UK.
Van Braeckel E; Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.
Rowe SM; Division of Pulmonary, Allergy, and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Tullis E; Division of Respirology, St Michael's Hospital, University of Toronto, Toronto, ON, Canada.
Mall MA; Department of Pulmonology, Immunology and Intensive Care Medicine, Charité-Universitätsmedizin Berlin, Berlin, Germany; Berlin Institute of Health, Berlin, Germany; German Center for Lung Research, Berlin, Germany.
Welter JJ; Division of Pediatric Pulmonology, Allergy, Immunology, and Sleep Medicine, New York Medical College, Valhalla, NY, USA.
Ramsey BW; Department of Pediatrics, Seattle Children's Hospital, University of Washington School of Medicine, Seattle, WA, USA.
McKee CM; Vertex Pharmaceuticals, Boston, MA, USA.
Marigowda G; Vertex Pharmaceuticals, Boston, MA, USA.
Moskowitz SM; Vertex Pharmaceuticals, Boston, MA, USA.
Waltz D; Vertex Pharmaceuticals, Boston, MA, USA.
Sosnay PR; Vertex Pharmaceuticals, Boston, MA, USA.
Simard C; Vertex Pharmaceuticals, Boston, MA, USA.
Ahluwalia N; Vertex Pharmaceuticals, Boston, MA, USA.
Xuan F; Vertex Pharmaceuticals, Boston, MA, USA.
Zhang Y; Vertex Pharmaceuticals, Boston, MA, USA.
Taylor-Cousar JL; Department of Medicine and Pediatrics, National Jewish Health, Denver, CO, USA.
McCoy KS; Department of Pediatrics, Nationwide Children's Hospital, Ohio State University, Columbus, OH, USA.
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Corporate Authors :
VX17-445-103 Trial Group
Źródło :
Lancet (London, England) [Lancet] 2019 Nov 23; Vol. 394 (10212), pp. 1940-1948. Date of Electronic Publication: 2019 Oct 31.
Typ publikacji :
Clinical Trial, Phase III; Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Aminophenols/*administration & dosage
Benzodioxoles/*administration & dosage
Chloride Channel Agonists/*administration & dosage
Cystic Fibrosis/*drug therapy
Cystic Fibrosis Transmembrane Conductance Regulator/*genetics
Indoles/*administration & dosage
Pyrazoles/*administration & dosage
Pyridines/*administration & dosage
Pyrrolidines/*administration & dosage
Quinolones/*administration & dosage
Adolescent ; Aminophenols/adverse effects ; Benzodioxoles/adverse effects ; Child ; Chloride Channel Agonists/adverse effects ; Cystic Fibrosis/genetics ; Double-Blind Method ; Drug Therapy, Combination ; Female ; Humans ; Indoles/adverse effects ; Male ; Pyrazoles/adverse effects ; Pyridines/adverse effects ; Pyrrolidines/adverse effects ; Quinolones/adverse effects ; Sweat/chemistry
Czasopismo naukowe

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