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Tytuł :
Burkholderia thailandensis Methylated Hydroxyalkylquinolines: Biosynthesis and Antimicrobial Activity in Cocultures.
Autorzy :
Klaus JR; Department of Molecular Biosciences, University of Kansas, Lawrence Kansas, USA.
Majerczyk C; Department of Biology, Oregon State University-Cascades, Bend, Oregon, USA.
Moon S; Department of Biology, Oregon State University-Cascades, Bend, Oregon, USA.
Eppler NA; Department of Molecular Biosciences, University of Kansas, Lawrence Kansas, USA.
Smith S; Department of Biology, Oregon State University-Cascades, Bend, Oregon, USA.
Tuma E; Department of Biology, Oregon State University-Cascades, Bend, Oregon, USA.
Groleau MC; Centre Armand-Frappier Santé Biotechnologie, Institut National de la Recherche Scientifique (INRS), Laval (Québec), Canada.
Asfahl KL; Department of Microbiology, University of Washington, Seattle Washington, USA.
Smalley NE; Department of Microbiology, University of Washington, Seattle Washington, USA.
Hayden HS; Department of Microbiology, University of Washington, Seattle Washington, USA.
Piochon M; Centre Armand-Frappier Santé Biotechnologie, Institut National de la Recherche Scientifique (INRS), Laval (Québec), Canada.
Ball P; Department of Biology, Oregon State University-Cascades, Bend, Oregon, USA.
Dandekar AA; Department of Microbiology, University of Washington, Seattle Washington, USA.
Gauthier C; Centre Armand-Frappier Santé Biotechnologie, Institut National de la Recherche Scientifique (INRS), Laval (Québec), Canada.
Déziel E; Centre Armand-Frappier Santé Biotechnologie, Institut National de la Recherche Scientifique (INRS), Laval (Québec), Canada.
Chandler JR; Department of Molecular Biosciences, University of Kansas, Lawrence Kansas, USA .
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Źródło :
Applied and environmental microbiology [Appl Environ Microbiol] 2020 Nov 24; Vol. 86 (24). Date of Electronic Publication: 2020 Nov 24 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Anti-Infective Agents/*pharmacology
Burkholderia/*metabolism
Quinolones/*metabolism
Methylation
SCR Organism :
Burkholderia thailandensis
Czasopismo naukowe
Tytuł :
Recent advances in the synthetic and medicinal perspective of quinolones: A review.
Autorzy :
Dhiman P; Department of Pharmaceutical Chemistry, ISF College of Pharmacy, G.T. Road, Ghal Kalan, Moga 142001, Punjab, India.
Arora N; Department of Pharmaceutical Chemistry, ISF College of Pharmacy, G.T. Road, Ghal Kalan, Moga 142001, Punjab, India.
Thanikachalam PV; Department of Pharmaceutical Chemistry, ISF College of Pharmacy, G.T. Road, Ghal Kalan, Moga 142001, Punjab, India.
Monga V; Department of Pharmaceutical Chemistry, ISF College of Pharmacy, G.T. Road, Ghal Kalan, Moga 142001, Punjab, India. Electronic address: .
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Źródło :
Bioorganic chemistry [Bioorg Chem] 2019 Nov; Vol. 92, pp. 103291. Date of Electronic Publication: 2019 Sep 19.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Anti-Infective Agents/*pharmacology
Anti-Inflammatory Agents, Non-Steroidal/*pharmacology
Antineoplastic Agents/*pharmacology
Carbonic Anhydrase Inhibitors/*pharmacology
Quinolones/*pharmacology
Animals ; Anti-Infective Agents/chemical synthesis ; Anti-Infective Agents/chemistry ; Anti-Inflammatory Agents, Non-Steroidal/chemical synthesis ; Anti-Inflammatory Agents, Non-Steroidal/chemistry ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Carbonic Anhydrase Inhibitors/chemical synthesis ; Carbonic Anhydrase Inhibitors/chemistry ; Humans ; Molecular Structure ; Quinolones/chemical synthesis ; Quinolones/chemistry
Czasopismo naukowe
Tytuł :
Efficacy and safety of the use of rebamipide in the scheme of triple eradication therapy of Helicobacter pylori infection: a prospective randomized comparative study.
Autorzy :
Andreev DN; A.I. Evdokimov Moscow State Medicine and Dentistry, University of the Ministry of Health of Russia, Moscow, Russia.
Maev IV; A.I. Evdokimov Moscow State Medicine and Dentistry, University of the Ministry of Health of Russia, Moscow, Russia.
Dicheva DT; A.I. Evdokimov Moscow State Medicine and Dentistry, University of the Ministry of Health of Russia, Moscow, Russia.
Samsonov AA; A.I. Evdokimov Moscow State Medicine and Dentistry, University of the Ministry of Health of Russia, Moscow, Russia.
Partzvania-Vinogradova EV; A.I. Evdokimov Moscow State Medicine and Dentistry, University of the Ministry of Health of Russia, Moscow, Russia.
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Źródło :
Terapevticheskii arkhiv [Ter Arkh] 2018 Aug 27; Vol. 90 (8), pp. 27-32.
Typ publikacji :
Journal Article; Randomized Controlled Trial
MeSH Terms :
Alanine/*analogs & derivatives
Anti-Infective Agents/*therapeutic use
Anti-Ulcer Agents/*therapeutic use
Helicobacter Infections/*drug therapy
Helicobacter pylori/*drug effects
Peptic Ulcer/*drug therapy
Quinolones/*therapeutic use
Adult ; Alanine/administration & dosage ; Alanine/adverse effects ; Alanine/therapeutic use ; Amoxicillin/administration & dosage ; Amoxicillin/therapeutic use ; Anti-Infective Agents/administration & dosage ; Anti-Ulcer Agents/administration & dosage ; Anti-Ulcer Agents/adverse effects ; Clarithromycin/administration & dosage ; Clarithromycin/therapeutic use ; Drug Administration Schedule ; Drug Therapy, Combination ; Female ; Helicobacter Infections/complications ; Helicobacter Infections/microbiology ; Humans ; Male ; Omeprazole/administration & dosage ; Omeprazole/therapeutic use ; Peptic Ulcer/complications ; Peptic Ulcer/microbiology ; Prospective Studies ; Quinolones/administration & dosage ; Quinolones/adverse effects ; Treatment Outcome
Czasopismo naukowe
Tytuł :
A comparative assessment of clinical, pharmacological and antimicrobial profile of novel anti-methicillin-resistant Staphylococcus aureus agent levonadifloxacin: Therapeutic role in nosocomial and community infections.
Autorzy :
Bakthavatchalam YD; Department of Clinical Microbiology, Christian Medical College, Vellore, Tamil Nadu, India.
Rao SV; Department of Critical Care Unit, Christian Medical College, Vellore, Tamil Nadu, India.
Isaac B; Department of Pulmonary Medicine, Christian Medical College, Vellore, Tamil Nadu, India.
Manesh A; Department of Internal Medicine and Infectious Diseases, Christian Medical College, Vellore, Tamil Nadu, India.
Nambi S; Department of Infectious Disease, Apollo Hospital, Chennai, Tamil Nadu, India.
Swaminathan S; Department of Infectious Disease, Global Hospital, Chennai, Tamil Nadu, India.
Nagvekar V; Department of Infectious disease, Lilavati Hospital, Mumbai, Maharashtra, India.
Nangia V; Department of Infectious Disease, Fortis Hospital, New Delhi, India.
John PV; Critical Care Medicine, Christian Medical College, Vellore, Tamil Nadu, India.
Veeraraghavan B; Department of Clinical Microbiology, Christian Medical College, Vellore, Tamil Nadu, India.
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Źródło :
Indian journal of medical microbiology [Indian J Med Microbiol] 2019 Oct-Dec; Vol. 37 (4), pp. 478-487.
Typ publikacji :
Comparative Study; Journal Article; Review
MeSH Terms :
Anti-Infective Agents/*therapeutic use
Cross Infection/*drug therapy
Methicillin-Resistant Staphylococcus aureus/*drug effects
Quinolizines/*therapeutic use
Quinolones/*therapeutic use
Staphylococcal Infections/*drug therapy
Humans ; Soft Tissue Infections/drug therapy
Czasopismo naukowe
Tytuł :
Discovery of Benzimidazole-Quinolone Hybrids as New Cleaving Agents toward Drug-Resistant Pseudomonas aeruginosa DNA.
Autorzy :
Wang YN; Institute of Bioorganic & Medicinal Chemistry, Key Laboratory of Applied Chemistry of Chongqing Municipality, School of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, P.R. China.
Bheemanaboina RRY; Institute of Bioorganic & Medicinal Chemistry, Key Laboratory of Applied Chemistry of Chongqing Municipality, School of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, P.R. China.
Gao WW; Institute of Bioorganic & Medicinal Chemistry, Key Laboratory of Applied Chemistry of Chongqing Municipality, School of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, P.R. China.
Kang J; Institute of Bioorganic & Medicinal Chemistry, Key Laboratory of Applied Chemistry of Chongqing Municipality, School of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, P.R. China.
Cai GX; Institute of Bioorganic & Medicinal Chemistry, Key Laboratory of Applied Chemistry of Chongqing Municipality, School of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, P.R. China.
Zhou CH; Institute of Bioorganic & Medicinal Chemistry, Key Laboratory of Applied Chemistry of Chongqing Municipality, School of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, P.R. China.
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Źródło :
ChemMedChem [ChemMedChem] 2018 May 23; Vol. 13 (10), pp. 1004-1017. Date of Electronic Publication: 2018 Apr 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Resistance, Multiple, Bacterial*
Anti-Infective Agents/*pharmacology
Benzimidazoles/*pharmacology
DNA, Bacterial/*chemistry
Pseudomonas aeruginosa/*drug effects
Quinolones/*pharmacology
Anti-Infective Agents/chemistry ; Benzimidazoles/chemistry ; Candida tropicalis/drug effects ; DNA Topoisomerases/chemistry ; DNA Topoisomerases/metabolism ; Drug Discovery ; Gene Expression Regulation, Bacterial/drug effects ; Molecular Structure ; Pseudomonas aeruginosa/genetics ; Quinolones/chemistry ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
New Quinolone-Based Thiosemicarbazones Showing Activity Against Plasmodium falciparum and Mycobacterium tuberculosis .
Autorzy :
Beteck RM; Division of Pharmaceutical Chemistry, Faculty of Pharmacy, Rhodes University, Grahamstown 6140, South Africa. .
Seldon R; Drug Discovery and Development Centre (H3-D), Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa. .
Jordaan A; SAMRC/NHLS/UCT Molecular Mycobacteriology Research Unit, Department of Pathology, University of Cape Town, Observatory 7925, South Africa. .
Warner DF; SAMRC/NHLS/UCT Molecular Mycobacteriology Research Unit, Department of Pathology, University of Cape Town, Observatory 7925, South Africa. .; Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Observatory 7925, South Africa. .; Wellcome Centre for Infectious Diseases Research in Africa, University of Cape Town, Observatory 7925, South Africa. .
Hoppe HC; Department of Biochemistry and Microbiology, Faculty of Science, Rhodes University, Grahamstown 6140, South Africa. .; Centre for Chemico- and Biomedicinal Research, Rhodes University, Grahamstown 6140, South Africa. .
Laming D; Centre for Chemico- and Biomedicinal Research, Rhodes University, Grahamstown 6140, South Africa. .
Khanye SD; Division of Pharmaceutical Chemistry, Faculty of Pharmacy, Rhodes University, Grahamstown 6140, South Africa. .; Centre for Chemico- and Biomedicinal Research, Rhodes University, Grahamstown 6140, South Africa. .
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2019 May 04; Vol. 24 (9). Date of Electronic Publication: 2019 May 04.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Infective Agents/*chemical synthesis
Mycobacterium tuberculosis/*drug effects
Plasmodium falciparum/*drug effects
Quinolones/*chemistry
Small Molecule Libraries/*chemical synthesis
Thiosemicarbazones/*chemistry
Animals ; Anti-Infective Agents/chemistry ; Anti-Infective Agents/pharmacology ; Candy ; Drug Interactions ; HeLa Cells ; Humans ; Inhibitory Concentration 50 ; Malaria, Falciparum/drug therapy ; Molecular Structure ; Small Molecule Libraries/chemistry ; Small Molecule Libraries/pharmacology ; Tuberculosis
Czasopismo naukowe
Tytuł :
Amino acid or peptide conjugates of acridine/acridone and quinoline/quinolone-containing drugs. A critical examination of their clinical effectiveness within a twenty-year timeframe in antitumor chemotherapy and treatment of infectious diseases.
Autorzy :
Kukowska M; Chair & Department of Chemical Technology of Drugs, Faculty of Pharmacy with Subfaculty of Laboratory Medicine, Medical University of Gdansk, Al. Gen. J. Hallera 107, 80-416 Gdansk, Poland. Electronic address: .
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Źródło :
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2017 Nov 15; Vol. 109, pp. 587-615. Date of Electronic Publication: 2017 Aug 24.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Acridines/*therapeutic use
Acridones/*therapeutic use
Anti-Infective Agents/*therapeutic use
Antineoplastic Agents/*therapeutic use
Quinolines/*therapeutic use
Quinolones/*therapeutic use
Acridines/chemistry ; Acridones/chemistry ; Amino Acids/chemistry ; Amino Acids/therapeutic use ; Animals ; Communicable Diseases/drug therapy ; Humans ; Neoplasms/drug therapy ; Peptides/chemistry ; Peptides/therapeutic use ; Quinolines/chemistry ; Quinolones/chemistry ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Nationwide study of outpatient oral antimicrobial utilization patterns for children in Japan (2013-2016).
Autorzy :
Kinoshita N; Division of Infectious Diseases, Department of Medical Subspecialties, National Center for Child Health and Development, Tokyo, Japan; Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan. Electronic address: .
Morisaki N; Department of Social Medicine, Research Institute, National Center for Child Health and Development, Tokyo, Japan. Electronic address: .
Uda K; Division of Infectious Diseases, Department of Medical Subspecialties, National Center for Child Health and Development, Tokyo, Japan; Division of Infectious Diseases, Department of Pediatrics, Tokyo Metropolitan Children's Medical Center, Tokyo, Japan. Electronic address: .
Kasai M; Division of Infectious Diseases, Department of Pediatrics, Hyogo Prefectural Kobe Children Hospital, Kobe, Japan. Electronic address: .
Horikoshi Y; Division of Infectious Diseases, Department of Pediatrics, Tokyo Metropolitan Children's Medical Center, Tokyo, Japan. Electronic address: .
Miyairi I; Division of Infectious Diseases, Department of Medical Subspecialties, National Center for Child Health and Development, Tokyo, Japan; Department of Microbiology, Immunology, and Biochemistry, University of Tennessee Health Science Center, Memphis, TN, USA. Electronic address: .
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Źródło :
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy [J Infect Chemother] 2019 Jan; Vol. 25 (1), pp. 22-27. Date of Electronic Publication: 2018 Nov 02.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Infective Agents/*administration & dosage
Drug Prescriptions/*statistics & numerical data
Drug Utilization/*statistics & numerical data
Outpatients/*statistics & numerical data
Adolescent ; Antimicrobial Stewardship ; Cephalosporins/administration & dosage ; Child ; Child, Preschool ; Humans ; Infant ; Japan ; Macrolides/administration & dosage ; Quinolones/administration & dosage ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Activity of innate antimicrobial peptides and ivacaftor against clinical cystic fibrosis respiratory pathogens.
Autorzy :
Payne JE; Halo Research Group, Queen's University Belfast, Belfast, UK; Centre for Experimental Medicine, School of Medicine, Dentistry & Biomedical Science, Queen's University Belfast, Belfast, UK.
Dubois AV; Centre for Experimental Medicine, School of Medicine, Dentistry & Biomedical Science, Queen's University Belfast, Belfast, UK.
Ingram RJ; Centre for Experimental Medicine, School of Medicine, Dentistry & Biomedical Science, Queen's University Belfast, Belfast, UK.
Weldon S; Airway Innate Immunity Group (AIIR), School of Medicine, Centre for Experimental Medicine, Dentistry & Biomedical Science, Queen's University Belfast, Belfast, UK.
Taggart CC; Airway Innate Immunity Group (AIIR), School of Medicine, Centre for Experimental Medicine, Dentistry & Biomedical Science, Queen's University Belfast, Belfast, UK.
Elborn JS; Halo Research Group, Queen's University Belfast, Belfast, UK; Centre for Experimental Medicine, School of Medicine, Dentistry & Biomedical Science, Queen's University Belfast, Belfast, UK.
Tunney MM; Halo Research Group, Queen's University Belfast, Belfast, UK; School of Pharmacy, Queen's University Belfast, Belfast, UK. Electronic address: .
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Źródło :
International journal of antimicrobial agents [Int J Antimicrob Agents] 2017 Sep; Vol. 50 (3), pp. 427-435. Date of Electronic Publication: 2017 Jun 27.
Typ publikacji :
Journal Article
MeSH Terms :
Aminophenols/*pharmacology
Anti-Infective Agents/*pharmacology
Antimicrobial Cationic Peptides/*pharmacology
Bacteria/*drug effects
Chloride Channel Agonists/*pharmacology
Cystic Fibrosis/*microbiology
Immunologic Factors/*pharmacology
Quinolones/*pharmacology
Aminophenols/therapeutic use ; Animals ; Anti-Infective Agents/therapeutic use ; Antimicrobial Cationic Peptides/therapeutic use ; Colony Count, Microbial ; Cystic Fibrosis/drug therapy ; Disease Models, Animal ; Drug Synergism ; Female ; Humans ; Immunologic Factors/therapeutic use ; Male ; Mice ; Microbial Sensitivity Tests ; Microbial Viability/drug effects ; Pseudomonas Infections/drug therapy ; Quinolones/therapeutic use ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Multi-targeting exploration of new 2-aminothiazolyl quinolones: Synthesis, antimicrobial evaluation, interaction with DNA, combination with topoisomerase IV and penetrability into cells.
Autorzy :
Cheng Y; Institute of Bioorganic & Medicinal Chemistry, Key Laboratory of Applied Chemistry of Chongqing Municipality, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China.
Avula SR; Institute of Bioorganic & Medicinal Chemistry, Key Laboratory of Applied Chemistry of Chongqing Municipality, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China.
Gao WW; Institute of Bioorganic & Medicinal Chemistry, Key Laboratory of Applied Chemistry of Chongqing Municipality, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China.
Addla D; Institute of Bioorganic & Medicinal Chemistry, Key Laboratory of Applied Chemistry of Chongqing Municipality, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China.
Tangadanchu VKR; Institute of Bioorganic & Medicinal Chemistry, Key Laboratory of Applied Chemistry of Chongqing Municipality, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China.
Zhang L; Institute of Bioorganic & Medicinal Chemistry, Key Laboratory of Applied Chemistry of Chongqing Municipality, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China.
Lin JM; Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu 610072, China. Electronic address: .
Zhou CH; Institute of Bioorganic & Medicinal Chemistry, Key Laboratory of Applied Chemistry of Chongqing Municipality, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, China. Electronic address: .
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2016 Nov 29; Vol. 124, pp. 935-945. Date of Electronic Publication: 2016 Oct 07.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Infective Agents/*metabolism
Anti-Infective Agents/*pharmacology
DNA/*metabolism
DNA Topoisomerase IV/*metabolism
Quinolones/*metabolism
Quinolones/*pharmacology
Animals ; Anti-Infective Agents/chemical synthesis ; Anti-Infective Agents/toxicity ; Biological Transport ; Cattle ; Cell Line ; Cell Membrane Permeability ; Chemistry Techniques, Synthetic ; DNA/chemistry ; DNA/genetics ; DNA Replication/drug effects ; DNA Topoisomerase IV/chemistry ; Drug Design ; Kinetics ; Mice ; Microbial Sensitivity Tests ; Molecular Docking Simulation ; Permeability ; Quinolones/chemical synthesis ; Quinolones/toxicity
Czasopismo naukowe
Tytuł :
Comparison of Efficacy of Antimicrobial Agents Among Hospitalized Patients With Mycoplasma pneumoniae Pneumonia in Japan During Large Epidemics of Macrolide-Resistant M. pneumoniae Infections: A Nationwide Observational Study.
Autorzy :
Tashiro M; Department of Infectious Diseases, Nagasaki University Graduate School of Biomedical Sciences, Japan.; Nagasaki University Infection Control and Education Centre, Nagasaki University Hospital, Japan.
Fushimi K; Department of Health Informatics and Policy, Tokyo Medical and Dental University, Graduate School of Medicine, Japan.
Kawano K; Nagasaki University Infection Control and Education Centre, Nagasaki University Hospital, Japan.
Takazono T; Department of Infectious Diseases, Nagasaki University Graduate School of Biomedical Sciences, Japan.; Second Department of Internal Medicine, Nagasaki University Hospital, Nagasaki, Japan.
Saijo T; Second Department of Internal Medicine, Nagasaki University Hospital, Nagasaki, Japan.
Yamamoto K; Second Department of Internal Medicine, Nagasaki University Hospital, Nagasaki, Japan.
Kurihara S; Nagasaki University Infection Control and Education Centre, Nagasaki University Hospital, Japan.
Imamura Y; Second Department of Internal Medicine, Nagasaki University Hospital, Nagasaki, Japan.
Miyazaki T; Department of Infectious Diseases, Nagasaki University Graduate School of Biomedical Sciences, Japan.; Second Department of Internal Medicine, Nagasaki University Hospital, Nagasaki, Japan.
Yanagihara K; Department of Laboratory Medicine, Nagasaki University Hospital, Nagasaki, Japan, Japan.
Mukae H; Second Department of Internal Medicine, Nagasaki University Hospital, Nagasaki, Japan.
Izumikawa K; Department of Infectious Diseases, Nagasaki University Graduate School of Biomedical Sciences, Japan.; Nagasaki University Infection Control and Education Centre, Nagasaki University Hospital, Japan.
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Źródło :
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2017 Nov 13; Vol. 65 (11), pp. 1837-1842.
Typ publikacji :
Comparative Study; Journal Article; Observational Study
MeSH Terms :
Drug Resistance, Bacterial*
Anti-Infective Agents/*therapeutic use
Macrolides/*therapeutic use
Mycoplasma pneumoniae/*drug effects
Pneumonia, Mycoplasma/*drug therapy
Adult ; Aged ; Anti-Infective Agents/administration & dosage ; Anti-Infective Agents/adverse effects ; Anti-Infective Agents/pharmacology ; Databases, Factual ; Epidemics ; Female ; Hospitalization ; Humans ; Japan/epidemiology ; Length of Stay ; Macrolides/administration & dosage ; Macrolides/adverse effects ; Macrolides/pharmacology ; Male ; Middle Aged ; Mycoplasma pneumoniae/genetics ; Pneumonia, Mycoplasma/diagnosis ; Pneumonia, Mycoplasma/epidemiology ; Pneumonia, Mycoplasma/mortality ; Polymerase Chain Reaction ; Quinolones/administration & dosage ; Quinolones/adverse effects ; Quinolones/therapeutic use ; RNA, Ribosomal, 23S ; Tetracycline/administration & dosage ; Tetracycline/adverse effects ; Tetracycline/therapeutic use
Czasopismo naukowe
Tytuł :
Effects of an Al(3+)- and Mg(2+)-containing antacid, ferrous sulfate, and calcium carbonate on the absorption of nemonoxacin (TG-873870) in healthy Chinese volunteers.
Autorzy :
Zhang YF; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Dai XJ; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Wang T; The First Hospital Affiliated to Lanzhou University, Lanzhou 730000, China.
Chen XY; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Liang L; The First Hospital Affiliated to Lanzhou University, Lanzhou 730000, China.
Qiao H; The First Hospital Affiliated to Lanzhou University, Lanzhou 730000, China.
Tsai CY; TaiGen Biotechnology Co Ltd, Taipei 11470, Taiwan, China.
Chang LW; TaiGen Biotechnology Co Ltd, Taipei 11470, Taiwan, China.
Huang PT; TaiGen Biotechnology Co Ltd, Taipei 11470, Taiwan, China.
Hsu CY; TaiGen Biotechnology Co Ltd, Taipei 11470, Taiwan, China.
Chang YT; TaiGen Biotechnology Co Ltd, Taipei 11470, Taiwan, China.
Tsai CE; TaiGen Biotechnology Co Ltd, Taipei 11470, Taiwan, China.
Zhong DF; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
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Źródło :
Acta pharmacologica Sinica [Acta Pharmacol Sin] 2014 Dec; Vol. 35 (12), pp. 1586-92. Date of Electronic Publication: 2014 Oct 20.
Typ publikacji :
Journal Article; Randomized Controlled Trial
MeSH Terms :
Aluminum Hydroxide/*administration & dosage
Antacids/*administration & dosage
Anti-Infective Agents/*pharmacokinetics
Calcium Carbonate/*administration & dosage
Ferrous Compounds/*administration & dosage
Gastrointestinal Absorption/*drug effects
Magnesium Hydroxide/*administration & dosage
Quinolones/*pharmacokinetics
Administration, Oral ; Adult ; Anti-Infective Agents/administration & dosage ; Anti-Infective Agents/blood ; Area Under Curve ; Asian Continental Ancestry Group ; China ; Cross-Over Studies ; Drug Administration Schedule ; Drug Interactions ; Half-Life ; Healthy Volunteers ; Humans ; Male ; Metabolic Clearance Rate ; Quinolones/administration & dosage ; Quinolones/blood ; Young Adult
Czasopismo naukowe
Tytuł :
Recent Advances in the Discovery of PqsD Inhibitors as Antimicrobial Agents.
Autorzy :
Zhou Z; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology, Ministry of Education, School of Pharmaceutical Sciences, Shandong University, 44, West Culture Road, Jinan, 250012, PR China).
Ma S; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology, Ministry of Education, School of Pharmaceutical Sciences, Shandong University, 44, West Culture Road, Jinan, 250012, PR China).
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Źródło :
ChemMedChem [ChemMedChem] 2017 Mar 17; Vol. 12 (6), pp. 420-425. Date of Electronic Publication: 2017 Mar 06.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Anti-Infective Agents/*chemistry
Bacterial Proteins/*antagonists & inhibitors
Quorum Sensing/*drug effects
Anti-Infective Agents/pharmacology ; Bacterial Proteins/metabolism ; Benzoates/chemistry ; Benzoates/pharmacology ; Carboxylic Acids/chemistry ; Carboxylic Acids/pharmacology ; Drug Resistance, Multiple, Bacterial/drug effects ; Pseudomonas aeruginosa/drug effects ; Pseudomonas aeruginosa/metabolism ; Quinolones/chemistry ; Quinolones/pharmacology ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Neuropsychiatric Effects of Antimicrobial Agents.
Autorzy :
Zareifopoulos N; Department of Pharmacology, University of Patras School of Medicine, Rion, 25004, Patras, Achaea, Greece. .
Panayiotakopoulos G; Department of Pharmacology, University of Patras School of Medicine, Rion, 25004, Patras, Achaea, Greece.
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Źródło :
Clinical drug investigation [Clin Drug Investig] 2017 May; Vol. 37 (5), pp. 423-437.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Anti-Infective Agents/*adverse effects
Mental Disorders/*chemically induced
Mental Disorders/*psychology
Aminoglycosides/adverse effects ; Anti-Bacterial Agents/adverse effects ; GABA-A Receptor Agonists/adverse effects ; Humans ; Mental Disorders/diagnosis ; Monoamine Oxidase Inhibitors/adverse effects ; Quinolones/adverse effects
Czasopismo naukowe
Tytuł :
Molecular characterization of antimicrobial susceptibility of Salmonella isolates: First identification of a plasmid carrying qnrD or oqxAB in Taiwan.
Autorzy :
Kao CY; Department of Medical Laboratory Science and Biotechnology, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Chen CA; Department of Medical Laboratory Science and Biotechnology, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Liu YF; Department of Medical Laboratory Science and Biotechnology, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Wu HM; Department of Medical Laboratory Science and Biotechnology, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Chiou CS; Centers for Disease Control, Taichung, Taiwan.
Yan JJ; Department of Pathology, National Cheng Kung University Hospital, Tainan, Taiwan.
Wu JJ; Department of Medical Laboratory Science and Biotechnology, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Center of Infectious Disease and Signaling Research, National Cheng Kung University, Tainan, Taiwan. Electronic address: .
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Źródło :
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi [J Microbiol Immunol Infect] 2017 Apr; Vol. 50 (2), pp. 214-223. Date of Electronic Publication: 2015 May 14.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Infective Agents/*pharmacology
Cephalosporins/*pharmacology
Quinolones/*pharmacology
Salmonella/*drug effects
Salmonella/*genetics
Anti-Bacterial Agents/pharmacology ; Bacterial Proteins/genetics ; Base Sequence ; DNA Gyrase/genetics ; Drug Resistance, Multiple, Bacterial ; Escherichia coli/genetics ; Genes, Bacterial ; Genotype ; Humans ; Microbial Sensitivity Tests/methods ; Plasmids/genetics ; Polymerase Chain Reaction ; Salmonella/isolation & purification ; Taiwan ; beta-Lactamases/genetics
Czasopismo naukowe
Tytuł :
Characterization of CTX-M enzymes, quinolone resistance determinants, and antimicrobial residues from hospital sewage, wastewater treatment plant, and river water.
Autorzy :
Conte D; Faculdades e Instituto de Pesquisa Pelé Pequeno Príncipe (FPP/IPPPP), Curitiba, Paraná, Brazil. Electronic address: .
Palmeiro JK; Faculdades e Instituto de Pesquisa Pelé Pequeno Príncipe (FPP/IPPPP), Curitiba, Paraná, Brazil; Hospital de Clínicas, Universidade Federal do Paraná (HC-UFPR), Curitiba, Paraná, Brazil. Electronic address: .
da Silva Nogueira K; Departamento de Patologia Básica, Setor de Ciências Biológicas, Universidade Federal do Paraná, Curitiba, Paraná, Brazil. Electronic address: .
de Lima TM; Sewage service unit, Companhia de Saneamento do Paraná (SANEPAR), Curitiba, Paraná, Brazil. Electronic address: .
Cardoso MA; Faculdades e Instituto de Pesquisa Pelé Pequeno Príncipe (FPP/IPPPP), Curitiba, Paraná, Brazil; Pharmacy Department, Health Sciences Sector, Universidade Federal do Paraná (UFPR), Curitiba, Paraná, Brazil. Electronic address: .
Pontarolo R; Pharmacy Department, Health Sciences Sector, Universidade Federal do Paraná (UFPR), Curitiba, Paraná, Brazil. Electronic address: .
Degaut Pontes FL; Pharmacy Department, Health Sciences Sector, Universidade Federal do Paraná (UFPR), Curitiba, Paraná, Brazil. Electronic address: .
Dalla-Costa LM; Faculdades e Instituto de Pesquisa Pelé Pequeno Príncipe (FPP/IPPPP), Curitiba, Paraná, Brazil; Hospital de Clínicas, Universidade Federal do Paraná (HC-UFPR), Curitiba, Paraná, Brazil. Electronic address: .
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Źródło :
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2017 Feb; Vol. 136, pp. 62-69. Date of Electronic Publication: 2016 Nov 04.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Infective Agents/*analysis
Quinolones/*toxicity
Sewage/*analysis
Waste Water/*analysis
Anti-Bacterial Agents/pharmacology ; Anti-Infective Agents/toxicity ; Bacterial Proteins/metabolism ; Ciprofloxacin/pharmacology ; Drug Resistance, Multiple, Bacterial/drug effects ; Enterobacteriaceae/isolation & purification ; Escherichia coli/drug effects ; Klebsiella pneumoniae/drug effects ; Plasmids/drug effects ; Rivers ; beta-Lactamases/metabolism
Czasopismo naukowe
Tytuł :
Antimicrobial resistance of Escherichia coli isolated in newly-hatched chickens and effect of amoxicillin treatment during their growth.
Autorzy :
Jiménez-Belenguer A; a Biotechnology Department. Centro Avanzado de Microbiología de Alimentos , Universitat Politècnica de València , Valencia , Spain.
Doménech E; b Institute of Food Engineering for Development (IUIAD), Food Technology Department , Universitat Politécnica de Valencia , Valencia , Spain.
Villagrá A; c Centro de Tecnología Animal CITA-IVIA , Castellon , Spain.
Fenollar A; d Biotechnology Department , Universitat Politècnica de València , Valencia , Spain.
Ferrús MA; a Biotechnology Department. Centro Avanzado de Microbiología de Alimentos , Universitat Politècnica de València , Valencia , Spain.
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Źródło :
Avian pathology : journal of the W.V.P.A [Avian Pathol] 2016 Aug; Vol. 45 (4), pp. 501-7.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Infective Agents/*pharmacology
Chickens/*microbiology
Escherichia coli/*drug effects
Escherichia coli Infections/*veterinary
Infectious Disease Transmission, Vertical/*veterinary
Poultry Diseases/*microbiology
Amoxicillin/pharmacology ; Animals ; Animals, Newborn ; Drug Resistance, Multiple, Bacterial ; Escherichia coli/growth & development ; Escherichia coli/isolation & purification ; Escherichia coli Infections/microbiology ; Escherichia coli Infections/transmission ; Male ; Microbial Sensitivity Tests/veterinary ; Nalidixic Acid/pharmacology ; Poultry Diseases/transmission ; Quinolones/pharmacology
Czasopismo naukowe
Tytuł :
Antimicrobial activities of ozenoxacin against isolates of propionibacteria and staphylococci from Japanese patients with acne vulgaris.
Autorzy :
Nakajima A; Strategic Research Planning & Management Department, Drug Development Laboratories, Kyoto R&D Center, Maruho Co., Ltd., 93 Awata-cho, Chudoji, Shimogyo-ku, Kyoto 600-8815, Japan.
Ikeda F; Strategic Research Planning & Management Department, Drug Development Laboratories, Kyoto R&D Center, Maruho Co., Ltd., 93 Awata-cho, Chudoji, Shimogyo-ku, Kyoto 600-8815, Japan.
Kanayama S; Strategic Research Planning & Management Department, Drug Development Laboratories, Kyoto R&D Center, Maruho Co., Ltd., 93 Awata-cho, Chudoji, Shimogyo-ku, Kyoto 600-8815, Japan.
Okamoto K; Strategic Research Planning & Management Department, Drug Development Laboratories, Kyoto R&D Center, Maruho Co., Ltd., 93 Awata-cho, Chudoji, Shimogyo-ku, Kyoto 600-8815, Japan.
Matsumoto T; Strategic Research Planning & Management Department, Drug Development Laboratories, Kyoto R&D Center, Maruho Co., Ltd., 93 Awata-cho, Chudoji, Shimogyo-ku, Kyoto 600-8815, Japan.
Ishii R; Strategic Research Planning & Management Department, Drug Development Laboratories, Kyoto R&D Center, Maruho Co., Ltd., 93 Awata-cho, Chudoji, Shimogyo-ku, Kyoto 600-8815, Japan.
Fujikawa A; Clinical Development Department, Kyoto R&D Center, Maruho Co., Ltd., Kyoto, Japan.
Takei K; Department of Bacteriology, BML, Inc., Saitama, Japan.
Kawashima M; Department of Dermatology, Tokyo Women's Medical University, Tokyo, Japan.
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Źródło :
Journal of medical microbiology [J Med Microbiol] 2016 Aug; Vol. 65 (8), pp. 745-750. Date of Electronic Publication: 2016 Jun 15.
Typ publikacji :
Journal Article
MeSH Terms :
Acne Vulgaris/*microbiology
Aminopyridines/*pharmacology
Anti-Infective Agents/*pharmacology
Propionibacterium/*drug effects
Quinolones/*pharmacology
Staphylococcus/*drug effects
Asian Continental Ancestry Group ; Fluoroquinolones/pharmacology ; Humans ; Microbial Sensitivity Tests ; Propionibacterium/isolation & purification ; Quinolizines/pharmacology ; Staphylococcus/isolation & purification
Czasopismo naukowe
Tytuł :
Dimethyl Sulfoxide Protects Escherichia coli from Rapid Antimicrobial-Mediated Killing.
Autorzy :
Mi H; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiang-An District, Xiamen, Fujian Province, China School of Public Health, Fujian Medical University, Minhou District, Fuzhou, Fujian Province, China.
Wang D; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiang-An District, Xiamen, Fujian Province, China.
Xue Y; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiang-An District, Xiamen, Fujian Province, China.
Zhang Z; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiang-An District, Xiamen, Fujian Province, China.
Niu J; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiang-An District, Xiamen, Fujian Province, China School of Public Health, Fujian Medical University, Minhou District, Fuzhou, Fujian Province, China Zhongshan Hospital, Affiliated Hospital of Xiamen University Medical School, Siming District, Xiamen, Fujian Province, China .
Hong Y; Public Health Research Institute and Department of Microbiology, Biochemistry, and Molecular Genetics, New Jersey Medical School, Rutgers Biomedical and Health Sciences, Newark, New Jersey, USA.
Drlica K; Public Health Research Institute and Department of Microbiology, Biochemistry, and Molecular Genetics, New Jersey Medical School, Rutgers Biomedical and Health Sciences, Newark, New Jersey, USA.
Zhao X; State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiang-An District, Xiamen, Fujian Province, China Public Health Research Institute and Department of Microbiology, Biochemistry, and Molecular Genetics, New Jersey Medical School, Rutgers Biomedical and Health Sciences, Newark, New Jersey, USA .
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Źródło :
Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2016 Jul 22; Vol. 60 (8), pp. 5054-8. Date of Electronic Publication: 2016 Jul 22 (Print Publication: 2016).
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Infective Agents/*pharmacology
Dimethyl Sulfoxide/*pharmacology
Escherichia coli/*drug effects
Ampicillin/pharmacology ; Escherichia coli/metabolism ; Kanamycin/pharmacology ; Microbial Sensitivity Tests ; Quinolones/pharmacology ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł :
Design, Synthesis, and Antimicrobial Evaluation of Novel Quinolone Imidazoles and Interactions with MRSA DNA.
Autorzy :
Zhang L; Key Laboratory of Applied Chemistry of Chongqing Municipality, Institute of Bioorganic & Medicinal Chemistry, School of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, China.
Kumar KV; Key Laboratory of Applied Chemistry of Chongqing Municipality, Institute of Bioorganic & Medicinal Chemistry, School of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, China.
Rasheed S; Key Laboratory of Applied Chemistry of Chongqing Municipality, Institute of Bioorganic & Medicinal Chemistry, School of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, China.
Geng RX; Key Laboratory of Applied Chemistry of Chongqing Municipality, Institute of Bioorganic & Medicinal Chemistry, School of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, China.
Zhou CH; Key Laboratory of Applied Chemistry of Chongqing Municipality, Institute of Bioorganic & Medicinal Chemistry, School of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, China.
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Źródło :
Chemical biology & drug design [Chem Biol Drug Des] 2015 Oct; Vol. 86 (4), pp. 648-55. Date of Electronic Publication: 2015 Mar 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anti-Infective Agents/*chemistry
Anti-Infective Agents/*pharmacology
Methicillin-Resistant Staphylococcus aureus/*drug effects
Anti-Infective Agents/chemical synthesis ; Chemistry Techniques, Synthetic ; Copper/chemistry ; Copper/metabolism ; DNA, Bacterial/drug effects ; DNA, Bacterial/metabolism ; Drug Design ; Drug Evaluation, Preclinical/methods ; Drug Resistance, Bacterial/drug effects ; Humans ; Imidazoles/chemistry ; Imidazoles/pharmacology ; Methicillin-Resistant Staphylococcus aureus/genetics ; Microbial Sensitivity Tests ; Quinolones/chemistry ; Quinolones/pharmacology ; Serum Albumin/chemistry
Czasopismo naukowe

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