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Tytuł:
Dihydrotanshinone I exhibits antitumor effects via β-catenin downregulation in papillary thyroid cancer cell lines.
Autorzy:
Molteni E; Department of Medicine, University of Udine, 33100, Udine, Italy.
Baldan F; Department of Medicine, University of Udine, 33100, Udine, Italy. .
Damante G; Department of Medicine, University of Udine, 33100, Udine, Italy.; Institute of Medical Genetics, Academic Hospital of Udine, Azienda Sanitaria Universitaria Friuli Centrale, 33100, Udine, Italy.
Allegri L; Department of Medicine, University of Udine, 33100, Udine, Italy.
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Źródło:
Scientific reports [Sci Rep] 2024 Apr 03; Vol. 14 (1), pp. 7853. Date of Electronic Publication: 2024 Apr 03.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Papillary*/drug therapy
Carcinoma, Papillary*/genetics
Carcinoma, Papillary*/metabolism
Thyroid Neoplasms*/drug therapy
Thyroid Neoplasms*/genetics
Thyroid Neoplasms*/metabolism
Furans*
Phenanthrenes*
Quinones*
Humans ; Thyroid Cancer, Papillary/drug therapy ; Thyroid Cancer, Papillary/pathology ; beta Catenin/genetics ; beta Catenin/metabolism ; Down-Regulation ; Cell Line, Tumor ; Wnt Signaling Pathway/genetics ; Cell Proliferation/physiology ; Cell Movement/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Streptomyces iakyrus TA 36 as First-Reported Source of Quinone Antibiotic γ-Rubromycin.
Autorzy:
Charousová I; Clinical Microbiology Laboratory, Unilabs Slovensko, s.r.o., J. Bellu 66, SK-03495 Likavka, Slovakia.; Institute of Biotechnology, Faculty of Biotechnology and Food Sciences, Slovak University of Agriculture, Nitra, Tr. A. Hlinku 2, SK-94976 Nitra, Slovakia.
Hlebová M; Department of Biology, Faculty of Natural Sciences, University of SS. Cyril and Methodius, Nám. J. Herdu 2, SK-91701 Trnava, Slovakia.
Hleba L; Institute of Biotechnology, Faculty of Biotechnology and Food Sciences, Slovak University of Agriculture, Nitra, Tr. A. Hlinku 2, SK-94976 Nitra, Slovakia.
Medo J; Institute of Biotechnology, Faculty of Biotechnology and Food Sciences, Slovak University of Agriculture, Nitra, Tr. A. Hlinku 2, SK-94976 Nitra, Slovakia.
Wink J; Microbial Strain Collection Group, Helmholtz Centre for Infection Research, Inhoffenstrasse 7, 38124 Braunschweig, Germany.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Aug 09; Vol. 28 (16). Date of Electronic Publication: 2023 Aug 09.
Typ publikacji:
Journal Article
MeSH Terms:
Quinones*/pharmacology
Streptomyces*
Phylogeny ; RNA, Ribosomal, 16S/genetics ; Anti-Bacterial Agents/pharmacology
SCR Organism:
Streptomyces iakyrus
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
It Takes Two to Tango, Part II: Synthesis of A-Ring Functionalised Quinones Containing Two Redox-Active Centres with Antitumour Activities.
Autorzy:
Oliveira JC; Institute of Exact Sciences, Department of Chemistry, Universidade Federal de Minas Gerais, UFMG, Belo Horizonte 31270-901, Brazil.
de Carvalho RL; Institute of Exact Sciences, Department of Chemistry, Universidade Federal de Minas Gerais, UFMG, Belo Horizonte 31270-901, Brazil.
Sampaio HGS; Institute of Exact Sciences, Department of Chemistry, Universidade Federal de Minas Gerais, UFMG, Belo Horizonte 31270-901, Brazil.
Honorato J; São Carlos Institute of Physics, Physics and Interdisciplinary Sciences Department, Universidade de São Paulo, USP, São Carlos 13560-970, Brazil.
Ellena JA; São Carlos Institute of Physics, Physics and Interdisciplinary Sciences Department, Universidade de São Paulo, USP, São Carlos 13560-970, Brazil.
Martins FT; Chemistry Institute, Universidade Federal de Goiás, UFG, Goiânia 74690-900, Brazil.
Pereira JVM; Department of Physiology and Pharmacology, Universidade Federal de Ceará, UFC, Fortaleza 60430-270, Brazil.
Costa PMS; Department of Physiology and Pharmacology, Universidade Federal de Ceará, UFC, Fortaleza 60430-270, Brazil.
Pessoa C; Department of Physiology and Pharmacology, Universidade Federal de Ceará, UFC, Fortaleza 60430-270, Brazil.
Ferreira RS; Biological Sciences Institute, Biochemistry and Immunology Department, Universidade Federal de Minas Gerais, UFMG, Belo Horizonte 31270-901, Brazil.
Araújo MH; Institute of Exact Sciences, Department of Chemistry, Universidade Federal de Minas Gerais, UFMG, Belo Horizonte 31270-901, Brazil.
Jacob C; Division of Bioorganic Chemistry, School of Pharmacy, University of Saarland, 66123 Saarbruecken, Germany.
da Silva Júnior EN; Institute of Exact Sciences, Department of Chemistry, Universidade Federal de Minas Gerais, UFMG, Belo Horizonte 31270-901, Brazil.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Feb 27; Vol. 28 (5). Date of Electronic Publication: 2023 Feb 27.
Typ publikacji:
Journal Article
MeSH Terms:
Quinones*/chemistry
Naphthoquinones*/chemistry
Animals ; Mice ; Benzoquinones ; Oxidation-Reduction ; Click Chemistry ; Cycloaddition Reaction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Straightforward Access to a New Class of Dual DYRK1A/CLK1 Inhibitors Possessing a Simple Dihydroquinoline Core.
Autorzy:
Ţînţaş ML; INSA Rouen Normandie, Univ. Rouen Normandie, CNRS UMR 6014 COBRA, FR 3038, F-76000 Rouen, France.
Peauger L; VFP Therapies, 15 rue François Couperin, 76000 Rouen, France.
Alix F; VFP Therapies, 15 rue François Couperin, 76000 Rouen, France.
Papamicaël C; INSA Rouen Normandie, Univ. Rouen Normandie, CNRS UMR 6014 COBRA, FR 3038, F-76000 Rouen, France.
Besson T; INSA Rouen Normandie, Univ. Rouen Normandie, CNRS UMR 6014 COBRA, FR 3038, F-76000 Rouen, France.
Sopková-de Oliveira Santos J; UNICAEN, CERMN (Centre d'Etudes et de Recherche sur le Médicament de Normandie), Normandie Univ., Bd Becquerel, F-14032 Caen, France.
Gembus V; VFP Therapies, 15 rue François Couperin, 76000 Rouen, France.
Levacher V; INSA Rouen Normandie, Univ. Rouen Normandie, CNRS UMR 6014 COBRA, FR 3038, F-76000 Rouen, France.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Dec 21; Vol. 28 (1). Date of Electronic Publication: 2022 Dec 21.
Typ publikacji:
Journal Article
MeSH Terms:
Protein Kinase Inhibitors*/chemistry
Protein Kinase Inhibitors*/pharmacology
Protein Kinase Inhibitors*/therapeutic use
Quinones*/chemistry
Quinones*/pharmacology
Quinones*/therapeutic use
Humans ; Alzheimer Disease/drug therapy ; Down Syndrome/drug therapy ; Glycogen Synthase Kinase 3/metabolism ; Molecular Docking Simulation ; Phosphorylation ; Dyrk Kinases
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Quinones as an Efficient Molecular Scaffold in the Antibacterial/Antifungal or Antitumoral Arsenal.
Autorzy:
Dahlem Junior MA; Aix-Marseille Université, CNRS, CINaM, 13009 Marseille, France.
Nguema Edzang RW; Aix-Marseille Université, CNRS, CINaM, 13009 Marseille, France.; Department of Chemistry and Biochemistry, University of Health Science (USS), Libreville 18231, Gabon.
Catto AL; Aix-Marseille Université, CNRS, CINaM, 13009 Marseille, France.; Center for Exact and Technological Sciences (CETEC), University of Taquari Valley, Lajeado 95914-014, RS, Brazil.
Raimundo JM; Aix-Marseille Université, CNRS, CINaM, 13009 Marseille, France.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Nov 15; Vol. 23 (22). Date of Electronic Publication: 2022 Nov 15.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Antifungal Agents*
Quinones*/pharmacology
Anti-Bacterial Agents/pharmacology ; Biofilms
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A 3D-Predicted Structure of the Amine Oxidase Domain of Lysyl Oxidase-Like 2.
Autorzy:
Meier AA; Department of Chemistry, The University of Kansas, Lawrence, KS 66045, USA.
Kuczera K; Department of Chemistry, The University of Kansas, Lawrence, KS 66045, USA.; Department of Molecular Biosciences, University of Kansas, Lawrence, KS 66045, USA.
Mure M; Department of Chemistry, The University of Kansas, Lawrence, KS 66045, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Nov 02; Vol. 23 (21). Date of Electronic Publication: 2022 Nov 02.
Typ publikacji:
Journal Article
MeSH Terms:
Protein-Lysine 6-Oxidase*/chemistry
Quinones*/chemistry
Models, Molecular ; Monoamine Oxidase ; Amines ; Amino Acid Oxidoreductases/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Construction of C-N Atropisomers by Aminocatalytic Enantioselective Addition of Indole-2-carboxaldehydes to o-Quinone Derivatives.
Autorzy:
Corti V; Department of Chemistry, Aarhus University, Aarhus, 8000 Aarhus C, Denmark.
Thøgersen MK; Department of Chemistry, Aarhus University, Aarhus, 8000 Aarhus C, Denmark.
Enemaerke VJ; Department of Chemistry, Aarhus University, Aarhus, 8000 Aarhus C, Denmark.
Rezayee NM; Department of Chemistry, Aarhus University, Aarhus, 8000 Aarhus C, Denmark.
Barløse CL; Department of Chemistry, Aarhus University, Aarhus, 8000 Aarhus C, Denmark.
Anker Jørgensen K; Department of Chemistry, Aarhus University, Aarhus, 8000 Aarhus C, Denmark.
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Źródło:
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2022 Oct 26; Vol. 28 (60), pp. e202202395. Date of Electronic Publication: 2022 Aug 23.
Typ publikacji:
Journal Article
MeSH Terms:
Indoles*/chemistry
Quinones*
Stereoisomerism ; Amines/chemistry ; Complex Mixtures
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Phase 1 Study to Investigate the Safety, Tolerability, and Pharmacokinetics of EPI-589 in Healthy Participants.
Autorzy:
Noda N; Clinical Research, Drug Development Division, Sumitomo Pharma Co., Ltd., Osaka, Japan.
Hamatani T; Clinical Research, Drug Development Division, Sumitomo Pharma Co., Ltd., Osaka, Japan.
Shibue Y; Clinical Research, Drug Development Division, Sumitomo Pharma Co., Ltd., Osaka, Japan.
Takagaki T; Clinical Research, Drug Development Division, Sumitomo Pharma Co., Ltd., Osaka, Japan.
Kitamura A; Clinical Research, Drug Development Division, Sumitomo Pharma Co., Ltd., Osaka, Japan.
Haranaka M; SOUSEIKAI Hakata Clinic, Fukuoka, Japan.
Ogama Y; SOUSEIKAI Sumida Hospital, Tokyo, Japan.
Kakuyama H; Clinical Research, Drug Development Division, Sumitomo Pharma Co., Ltd., Osaka, Japan.
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Źródło:
Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2022 Oct; Vol. 11 (10), pp. 1136-1146. Date of Electronic Publication: 2022 Aug 21.
Typ publikacji:
Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms:
Oxidoreductases*
Quinones*
Administration, Oral ; Area Under Curve ; Drug Administration Schedule ; Healthy Volunteers ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Biosensing firefly luciferin synthesis in bacteria reveals a cysteine-dependent quinone detoxification route in Coleoptera.
Autorzy:
de Souza DR; Graduate Program of Biotechnology and Environmental Monitoring, Federal University of São Carlos, Sorocaba, Brazil.
Silva JR; Departament of Physics, Chemistry and Mathematics, Federal University of São Carlos, Sorocaba, Brazil.
Moreira A; Departament of Physics, Chemistry and Mathematics, Federal University of São Carlos, Sorocaba, Brazil.
Viviani VR; Graduate Program of Biotechnology and Environmental Monitoring, Federal University of São Carlos, Sorocaba, Brazil. .; Departament of Physics, Chemistry and Mathematics, Federal University of São Carlos, Sorocaba, Brazil. .
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Źródło:
Scientific reports [Sci Rep] 2022 Aug 31; Vol. 12 (1), pp. 14815. Date of Electronic Publication: 2022 Aug 31.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Coleoptera*/metabolism
Firefly Luciferin*/metabolism
Luciferases, Firefly*/metabolism
Quinones*/metabolism
Animals ; Cysteine/metabolism ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Fireflies/genetics ; Luciferases/genetics ; Luciferases/metabolism ; Luciferins ; Luminescent Measurements ; Saccharomycetales/metabolism
SCR Organism:
Komagataella pastoris
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Hydroxysafflor yellow A protects against ulcerative colitis via suppressing TLR4/NF-κB signaling pathway.
Autorzy:
Feng Z; Department of Anorectal, Jiangxi Province Hospital of Integrated Chinese Western Medicine, Nanchang, China.
Zhou P; Department of Anorectal, Jiangxi Province Hospital of Integrated Chinese Western Medicine, Nanchang, China.
Wu X; Department of Anorectal, Jiangxi Province Hospital of Integrated Chinese Western Medicine, Nanchang, China.
Zhang J; Department of Anorectal, Jiangxi Province Hospital of Integrated Chinese Western Medicine, Nanchang, China.
Zhang M; Department of Anorectal, Jiangxi Province Hospital of Integrated Chinese Western Medicine, Nanchang, China.
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Źródło:
Chemical biology & drug design [Chem Biol Drug Des] 2022 Jun; Vol. 99 (6), pp. 897-907. Date of Electronic Publication: 2022 Mar 29.
Typ publikacji:
Journal Article
MeSH Terms:
Chalcone*/analogs & derivatives
Chalcone*/pharmacology
Colitis, Ulcerative*/chemically induced
Colitis, Ulcerative*/drug therapy
Colitis, Ulcerative*/metabolism
NF-kappa B*/antagonists & inhibitors
NF-kappa B*/metabolism
Quinones*/pharmacology
Toll-Like Receptor 4*/antagonists & inhibitors
Toll-Like Receptor 4*/metabolism
Animals ; Body Weight/drug effects ; Colon/metabolism ; Colon/pathology ; Disease Models, Animal ; Lipopolysaccharides/pharmacology ; Rats ; Rats, Sprague-Dawley ; Signal Transduction/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Pharmacological Actions, Molecular Mechanisms, Pharmacokinetic Progressions, and Clinical Applications of Hydroxysafflor Yellow A in Antidiabetic Research.
Autorzy:
Zhang X; School of Pharmacy, Shanxi Medical University, Taiyuan 030001, China.
Shen D; School of Pharmacy, Shanxi Medical University, Taiyuan 030001, China.
Feng Y; School of Pharmacy, Shanxi Medical University, Taiyuan 030001, China.
Li Y; Department of Pharmacy, Fifth Hospital of Shanxi Medical University (Shanxi Provincial People's Hospital), Taiyuan 030012, China.
Liao H; Department of Pharmacy, Fifth Hospital of Shanxi Medical University (Shanxi Provincial People's Hospital), Taiyuan 030012, China.
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Źródło:
Journal of immunology research [J Immunol Res] 2021 Dec 13; Vol. 2021, pp. 4560012. Date of Electronic Publication: 2021 Dec 13 (Print Publication: 2021).
Typ publikacji:
Journal Article; Review
MeSH Terms:
Research*
Chalcone/*analogs & derivatives
Hypoglycemic Agents/*pharmacology
Quinones/*pharmacology
Animals ; Apoptosis/drug effects ; Biological Products/pharmacology ; Biological Products/therapeutic use ; Biomarkers ; Carthamus tinctorius ; Chalcone/chemistry ; Chalcone/pharmacology ; Chalcone/therapeutic use ; Clinical Studies as Topic ; Drug Administration Routes ; Drug Evaluation, Preclinical ; Drug Monitoring ; Drugs, Chinese Herbal/pharmacology ; Drugs, Chinese Herbal/therapeutic use ; Humans ; Hypoglycemic Agents/chemistry ; Hypoglycemic Agents/therapeutic use ; Quinones/chemistry ; Quinones/therapeutic use ; Signal Transduction/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Seriniquinones as Therapeutic Leads for Treatment of BRAF and NRAS Mutant Melanomas.
Autorzy:
Hirata AS; Department of Pharmacology, Institute of Biomedical Sciences, University of São Paulo, São Paulo 05508-900, SP, Brazil.
Rezende-Teixeira P; Department of Pharmacology, Institute of Biomedical Sciences, University of São Paulo, São Paulo 05508-900, SP, Brazil.
Machado-Neto JA; Department of Pharmacology, Institute of Biomedical Sciences, University of São Paulo, São Paulo 05508-900, SP, Brazil.
Jimenez PC; Institute of Marine Science, Federal University of São Paulo, Santos 11070-100, SP, Brazil.
Clair JJ; Department of Chemistry and Biochemistry, University of California, La Jolla, San Diego, CA 92093-0358, USA.
Fenical W; Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California, La Jolla, San Diego, CA 92093-0204, USA.
Costa-Lotufo LV; Department of Pharmacology, Institute of Biomedical Sciences, University of São Paulo, São Paulo 05508-900, SP, Brazil.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 Dec 04; Vol. 26 (23). Date of Electronic Publication: 2021 Dec 04.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents/*pharmacology
GTP Phosphohydrolases/*genetics
Melanoma/*drug therapy
Membrane Proteins/*genetics
Proto-Oncogene Proteins B-raf/*genetics
Quinones/*pharmacology
Antineoplastic Agents/chemistry ; Apoptosis/drug effects ; Autophagy/drug effects ; Cell Line, Tumor ; Drug Discovery ; Humans ; Melanoma/genetics ; Mutation/genetics ; Quinones/chemistry ; Serine/analogs & derivatives ; Serine/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Electrochemistry of Quinones with Respect to their Role in Biomedical Chemistry.
Autorzy:
Krayz GT; Department of Chemistry, Ben-Gurion University of the Negev, Beer-Sheva, 84105, Israel.
Bittner S; Department of Chemistry, Ben-Gurion University of the Negev, Beer-Sheva, 84105, Israel.
Dhiman A; Department of Chemistry, Ben-Gurion University of the Negev, Beer-Sheva, 84105, Israel.
Becker JY; Department of Chemistry, Ben-Gurion University of the Negev, Beer-Sheva, 84105, Israel.
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Źródło:
Chemical record (New York, N.Y.) [Chem Rec] 2021 Sep; Vol. 21 (9), pp. 2332-2343. Date of Electronic Publication: 2021 Jun 09.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Amino Acids*
Quinones*
Anions ; Electrochemistry ; Oxidation-Reduction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Oxidation of Equol by Tyrosinase Produces a Unique Di- ortho -Quinone: Possible Implications for Melanocyte Toxicity.
Autorzy:
Tanaka H; Department of Medical Technology, School of Health Sciences, Gifu University of Medical Science, 795-1 Nagamine, Ichihiraga, Seki 510-3892, Japan.; Institute for Melanin Chemistry, Fujita Health University, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake 470-1192, Japan.
Ito S; Institute for Melanin Chemistry, Fujita Health University, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake 470-1192, Japan.
Ojika M; Graduate School of Bioagricultural Sciences, Nagoya University, Chikusa-ku, Nagoya 464-8601, Japan.
Nishimaki-Mogami T; Division of Biochemistry, National Institute of Health Sciences, Kawasaki-ku, Kawasaki 210-9501, Japan.
Kondo K; Division of Biochemistry, National Institute of Health Sciences, Kawasaki-ku, Kawasaki 210-9501, Japan.
Wakamatsu K; Institute for Melanin Chemistry, Fujita Health University, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake 470-1192, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 24; Vol. 22 (17). Date of Electronic Publication: 2021 Aug 24.
Typ publikacji:
Journal Article
MeSH Terms:
Equol/*metabolism
Melanocytes/*drug effects
Oxidants/*toxicity
Quinones/*toxicity
Cysteine/analogs & derivatives ; Cysteine/metabolism ; Glutathione/metabolism ; HEK293 Cells ; Humans ; Monophenol Monooxygenase/metabolism ; Oxidants/metabolism ; Protein Binding ; Quinones/metabolism ; Serum Albumin, Bovine/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Cannabinoquinones: Synthesis and Biological Profile.
Autorzy:
Caprioglio D; Dipartimento di Scienze del Farmaco, Università del Piemonte Orientale, Largo Donegani 2, 28100 Novara, Italy.
Mattoteia D; Dipartimento di Scienze del Farmaco, Università del Piemonte Orientale, Largo Donegani 2, 28100 Novara, Italy.
Taglialatela-Scafati O; Dipartimento di Farmacia, Università di Napoli Federico II, Via Montesano 49, 80131 Napoli, Italy.
Muñoz E; Instituto Maimónides de Investigación Biomédica de Córdoba, 14004 Córdoba, Spain.; Departamento de Biología Celular, Fisiología e Inmunología, Universidad de Córdoba, 14071 Córdoba, Spain.; Hospital Universitario Reina Sofía, Universidad de Córdoba, 14004 Córdoba, Spain.
Appendino G; Dipartimento di Scienze del Farmaco, Università del Piemonte Orientale, Largo Donegani 2, 28100 Novara, Italy.
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Źródło:
Biomolecules [Biomolecules] 2021 Jul 05; Vol. 11 (7). Date of Electronic Publication: 2021 Jul 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Cannabinoids/*chemistry
Quinones/*chemistry
Cannabinoids/therapeutic use ; Humans ; Oxidation-Reduction ; Quinones/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cannabinoid Quinones-A Review and Novel Observations.
Autorzy:
Kogan NM; Institute for Drug Research, Medical Faculty, Hebrew University, Jerusalem 91120, Israel.
Peters M; Institute for Drug Research, Medical Faculty, Hebrew University, Jerusalem 91120, Israel.
Mechoulam R; Institute for Drug Research, Medical Faculty, Hebrew University, Jerusalem 91120, Israel.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 Mar 21; Vol. 26 (6). Date of Electronic Publication: 2021 Mar 21.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Neoplasms, Experimental*/drug therapy
Neoplasms, Experimental*/enzymology
Quinones*/chemistry
Quinones*/therapeutic use
Topoisomerase II Inhibitors*/chemistry
Topoisomerase II Inhibitors*/therapeutic use
Cannabidiol/*analogs & derivatives
Neoplasm Proteins/*antagonists & inhibitors
Poly-ADP-Ribose Binding Proteins/*antagonists & inhibitors
Animals ; Cannabidiol/chemistry ; Cannabidiol/therapeutic use ; DNA Topoisomerases, Type II/metabolism ; Humans ; Mice ; Mice, Nude ; Neoplasm Proteins/metabolism ; Poly-ADP-Ribose Binding Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The 3,4-Quinones of Estrone and Estradiol Are the Initiators of Cancer whereas Resveratrol and N -acetylcysteine Are the Preventers.
Autorzy:
Cavalieri E; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, 986805 Nebraska Medical Center, Omaha, NE 68198-6805, USA.
Rogan E; Department of Environmental, Agricultural and Occupational Health, University of Nebraska Medical Center, 984388 Nebraska Medical Center, Omaha, NE 68198-4388, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 30; Vol. 22 (15). Date of Electronic Publication: 2021 Jul 30.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Acetylcysteine/*pharmacology
Carcinogenesis/*drug effects
Estradiol/*pharmacology
Estrone/*pharmacology
Quinones/*pharmacology
Resveratrol/*pharmacology
Animals ; Antioxidants/pharmacology ; Carcinogenesis/genetics ; DNA Adducts ; Estradiol/toxicity ; Estrogens/pharmacology ; Estrogens/toxicity ; Estrone/toxicity ; Humans ; Quinones/toxicity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The signaling role of extracellular ATP in co-culture of Shiraia sp. S9 and Pseudomonas fulva SB1 for enhancing hypocrellin A production.
Autorzy:
Li XP; College of Pharmaceutical Sciences, Soochow University, Suzhou, 215123, China.
Zhou LL; College of Pharmaceutical Sciences, Soochow University, Suzhou, 215123, China.
Guo YH; College of Pharmaceutical Sciences, Soochow University, Suzhou, 215123, China.
Wang JW; College of Pharmaceutical Sciences, Soochow University, Suzhou, 215123, China. .
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Źródło:
Microbial cell factories [Microb Cell Fact] 2021 Jul 23; Vol. 20 (1), pp. 144. Date of Electronic Publication: 2021 Jul 23.
Typ publikacji:
Journal Article
MeSH Terms:
Adenosine Triphosphate/*metabolism
Ascomycota/*metabolism
Perylene/*analogs & derivatives
Phenol/*metabolism
Pseudomonas/*metabolism
Quinones/*metabolism
Signal Transduction/*drug effects
Adenosine Triphosphate/pharmacology ; Ascomycota/drug effects ; Cytosol/metabolism ; Perylene/analysis ; Perylene/metabolism ; Phenol/analysis ; Pseudomonas/drug effects ; Quinones/analysis ; Reactive Oxygen Species/metabolism
SCR Organism:
Pseudomonas fulva
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Ultrasound-Enhanced Self-Exciting Photodynamic Therapy Based on Hypocrellin B.
Autorzy:
Ding Y; Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.; School of Future Technology, University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.
Liu W; Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.; School of Future Technology, University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.
Wu J; Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.
Zheng X; Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.
Ge J; Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.; School of Future Technology, University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.
Ren H; Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.
Zhang W; Center Of Super-Diamond and Advanced Films (COSDAF) & Department of Materials Science and Engineering, City University of Hong Kong, Hong Kong SAR, P. R. China.
Lee CS; Center Of Super-Diamond and Advanced Films (COSDAF) & Department of Materials Science and Engineering, City University of Hong Kong, Hong Kong SAR, P. R. China.
Wang P; Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.; School of Future Technology, University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.
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Źródło:
Chemistry, an Asian journal [Chem Asian J] 2021 May 17; Vol. 16 (10), pp. 1221-1224. Date of Electronic Publication: 2021 Apr 21.
Typ publikacji:
Journal Article
MeSH Terms:
Photochemotherapy*
Ultrasonic Waves*
Antineoplastic Agents/*pharmacology
Metal-Organic Frameworks/*pharmacology
Perylene/*analogs & derivatives
Photosensitizing Agents/*pharmacology
Quinones/*pharmacology
Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Drug Screening Assays, Antitumor ; Humans ; Metal-Organic Frameworks/chemical synthesis ; Metal-Organic Frameworks/chemistry ; Models, Molecular ; Particle Size ; Perylene/chemistry ; Perylene/pharmacology ; Photosensitizing Agents/chemical synthesis ; Photosensitizing Agents/chemistry ; Quinones/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effect of respiratory inhibitors and quinone analogues on the aerobic electron transport system of Eikenella corrodens.
Autorzy:
Jaramillo-Lanchero RD; Grupo de Investigación de Biomembranas (GIBIOM), CIFACS, Facultad Ciencias de La Salud, Centro Seccional de Investigación (CIUL), Universidad Libre Campus Barranquilla, Barranquilla, Colombia. .
Suarez-Alvarez P; Grupo de Micología, Departamento de Microbiología, Facultad de Medicina, Universidad de Cartagena, Campus Zaragocilla, Cartagena, Colombia.
Teheran-Sierra L; Grupo de Investigación de Biomembranas (GIBIOM), CIFACS, Facultad Ciencias de La Salud, Centro Seccional de Investigación (CIUL), Universidad Libre Campus Barranquilla, Barranquilla, Colombia.; School of Agricultural and Veterinary Sciences, Technology Department, São Paulo State University (Unesp), Via de Acesso Prof. Paulo Donato Castellane s/n, Jaboticabal, SP, 14884-900, Brazil.
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Źródło:
Scientific reports [Sci Rep] 2021 Apr 26; Vol. 11 (1), pp. 8987. Date of Electronic Publication: 2021 Apr 26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Bacterial Proteins*/antagonists & inhibitors
Bacterial Proteins*/metabolism
Electron Transport Complex I*/antagonists & inhibitors
Electron Transport Complex I*/metabolism
Quinones*/chemistry
Quinones*/pharmacology
Uncoupling Agents*/chemistry
Uncoupling Agents*/pharmacology
Eikenella corrodens/*enzymology
Oxygen Consumption/*drug effects
Aerobiosis/drug effects ; Electron Transport/drug effects ; NAD/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 8208

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