Temat: "Quinones" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Dihydrotanshinone I exhibits antitumor effects via β-catenin downregulation in papillary thyroid cancer cell lines.
Autorzy:: Molteni E; Department of Medicine, University of Udine, 33100, Udine, Italy.
Baldan F; Department of Medicine, University of Udine, 33100, Udine, Italy. .
Damante G; Department of Medicine, University of Udine, 33100, Udine, Italy.; Institute of Medical Genetics, Academic Hospital of Udine, Azienda Sanitaria Universitaria Friuli Centrale, 33100, Udine, Italy.
Allegri L; Department of Medicine, University of Udine, 33100, Udine, Italy.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2024 Apr 03; Vol. 14 (1), pp. 7853. Date of Electronic Publication: 2024 Apr 03.
Typ publikacji:: Journal Article
MeSH Terms:: Carcinoma, Papillary*/drug therapy
Carcinoma, Papillary*/genetics
Carcinoma, Papillary*/metabolism
Thyroid Neoplasms*/drug therapy
Thyroid Neoplasms*/genetics
Thyroid Neoplasms*/metabolism
Furans*
Phenanthrenes*
Quinones*
Humans ; Thyroid Cancer, Papillary/drug therapy ; Thyroid Cancer, Papillary/pathology ; beta Catenin/genetics ; beta Catenin/metabolism ; Down-Regulation ; Cell Line, Tumor ; Wnt Signaling Pathway/genetics ; Cell Proliferation/physiology ; Cell Movement/genetics

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Skocz do pozycji: 2.

Tytuł:: Streptomyces iakyrus TA 36 as First-Reported Source of Quinone Antibiotic γ-Rubromycin.
Autorzy:: Charousová I; Clinical Microbiology Laboratory, Unilabs Slovensko, s.r.o., J. Bellu 66, SK-03495 Likavka, Slovakia.; Institute of Biotechnology, Faculty of Biotechnology and Food Sciences, Slovak University of Agriculture, Nitra, Tr. A. Hlinku 2, SK-94976 Nitra, Slovakia.
Hlebová M; Department of Biology, Faculty of Natural Sciences, University of SS. Cyril and Methodius, Nám. J. Herdu 2, SK-91701 Trnava, Slovakia.
Hleba L; Institute of Biotechnology, Faculty of Biotechnology and Food Sciences, Slovak University of Agriculture, Nitra, Tr. A. Hlinku 2, SK-94976 Nitra, Slovakia.
Medo J; Institute of Biotechnology, Faculty of Biotechnology and Food Sciences, Slovak University of Agriculture, Nitra, Tr. A. Hlinku 2, SK-94976 Nitra, Slovakia.
Wink J; Microbial Strain Collection Group, Helmholtz Centre for Infection Research, Inhoffenstrasse 7, 38124 Braunschweig, Germany.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Aug 09; Vol. 28 (16). Date of Electronic Publication: 2023 Aug 09.
Typ publikacji:: Journal Article
MeSH Terms:: Quinones*/pharmacology
Streptomyces*
Phylogeny ; RNA, Ribosomal, 16S/genetics ; Anti-Bacterial Agents/pharmacology
SCR Organism:: Streptomyces iakyrus

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Skocz do pozycji: 3.

Tytuł:: It Takes Two to Tango, Part II: Synthesis of A-Ring Functionalised Quinones Containing Two Redox-Active Centres with Antitumour Activities.
Autorzy:: Oliveira JC; Institute of Exact Sciences, Department of Chemistry, Universidade Federal de Minas Gerais, UFMG, Belo Horizonte 31270-901, Brazil.
de Carvalho RL; Institute of Exact Sciences, Department of Chemistry, Universidade Federal de Minas Gerais, UFMG, Belo Horizonte 31270-901, Brazil.
Sampaio HGS; Institute of Exact Sciences, Department of Chemistry, Universidade Federal de Minas Gerais, UFMG, Belo Horizonte 31270-901, Brazil.
Honorato J; São Carlos Institute of Physics, Physics and Interdisciplinary Sciences Department, Universidade de São Paulo, USP, São Carlos 13560-970, Brazil.
Ellena JA; São Carlos Institute of Physics, Physics and Interdisciplinary Sciences Department, Universidade de São Paulo, USP, São Carlos 13560-970, Brazil.
Martins FT; Chemistry Institute, Universidade Federal de Goiás, UFG, Goiânia 74690-900, Brazil.
Pereira JVM; Department of Physiology and Pharmacology, Universidade Federal de Ceará, UFC, Fortaleza 60430-270, Brazil.
Costa PMS; Department of Physiology and Pharmacology, Universidade Federal de Ceará, UFC, Fortaleza 60430-270, Brazil.
Pessoa C; Department of Physiology and Pharmacology, Universidade Federal de Ceará, UFC, Fortaleza 60430-270, Brazil.
Ferreira RS; Biological Sciences Institute, Biochemistry and Immunology Department, Universidade Federal de Minas Gerais, UFMG, Belo Horizonte 31270-901, Brazil.
Araújo MH; Institute of Exact Sciences, Department of Chemistry, Universidade Federal de Minas Gerais, UFMG, Belo Horizonte 31270-901, Brazil.
Jacob C; Division of Bioorganic Chemistry, School of Pharmacy, University of Saarland, 66123 Saarbruecken, Germany.
da Silva Júnior EN; Institute of Exact Sciences, Department of Chemistry, Universidade Federal de Minas Gerais, UFMG, Belo Horizonte 31270-901, Brazil.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Feb 27; Vol. 28 (5). Date of Electronic Publication: 2023 Feb 27.
Typ publikacji:: Journal Article
MeSH Terms:: Quinones*/chemistry
Naphthoquinones*/chemistry
Animals ; Mice ; Benzoquinones ; Oxidation-Reduction ; Click Chemistry ; Cycloaddition Reaction

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Skocz do pozycji: 4.

Tytuł:: Ongoing evolution of the Mycobacterium tuberculosis lactate dehydrogenase reveals the pleiotropic effects of bacterial adaption to host pressure.
Autorzy:: Stanley S; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States of America.
Wang X; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States of America.
Liu Q; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States of America.
Kwon YY; Department of Molecular Metabolism, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, United States of America.
Frey AM; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States of America.
Hicks ND; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States of America.
Vickers AJ; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States of America.
Hui S; Department of Molecular Metabolism, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, United States of America.
Fortune SM; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States of America.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, United States of America.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.; Pokaż więcej
Źródło:: PLoS pathogens [PLoS Pathog] 2024 Feb 29; Vol. 20 (2), pp. e1012050. Date of Electronic Publication: 2024 Feb 29 (Print Publication: 2024).
Typ publikacji:: Journal Article
MeSH Terms:: Mycobacterium tuberculosis*/metabolism
Humans ; L-Lactate Dehydrogenase ; Lactic Acid/metabolism ; Pyruvates/metabolism ; Quinones/metabolism ; Phosphates/metabolism

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Skocz do pozycji: 5.

Tytuł:: Straightforward Access to a New Class of Dual DYRK1A/CLK1 Inhibitors Possessing a Simple Dihydroquinoline Core.
Autorzy:: Ţînţaş ML; INSA Rouen Normandie, Univ. Rouen Normandie, CNRS UMR 6014 COBRA, FR 3038, F-76000 Rouen, France.
Peauger L; VFP Therapies, 15 rue François Couperin, 76000 Rouen, France.
Alix F; VFP Therapies, 15 rue François Couperin, 76000 Rouen, France.
Papamicaël C; INSA Rouen Normandie, Univ. Rouen Normandie, CNRS UMR 6014 COBRA, FR 3038, F-76000 Rouen, France.
Besson T; INSA Rouen Normandie, Univ. Rouen Normandie, CNRS UMR 6014 COBRA, FR 3038, F-76000 Rouen, France.
Sopková-de Oliveira Santos J; UNICAEN, CERMN (Centre d'Etudes et de Recherche sur le Médicament de Normandie), Normandie Univ., Bd Becquerel, F-14032 Caen, France.
Gembus V; VFP Therapies, 15 rue François Couperin, 76000 Rouen, France.
Levacher V; INSA Rouen Normandie, Univ. Rouen Normandie, CNRS UMR 6014 COBRA, FR 3038, F-76000 Rouen, France.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2022 Dec 21; Vol. 28 (1). Date of Electronic Publication: 2022 Dec 21.
Typ publikacji:: Journal Article
MeSH Terms:: Protein Kinase Inhibitors*/chemistry
Protein Kinase Inhibitors*/pharmacology
Protein Kinase Inhibitors*/therapeutic use
Quinones*/chemistry
Quinones*/pharmacology
Quinones*/therapeutic use
Humans ; Alzheimer Disease/drug therapy ; Down Syndrome/drug therapy ; Glycogen Synthase Kinase 3/metabolism ; Molecular Docking Simulation ; Phosphorylation ; Dyrk Kinases

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Skocz do pozycji: 6.

Tytuł:: Quinones as an Efficient Molecular Scaffold in the Antibacterial/Antifungal or Antitumoral Arsenal.
Autorzy:: Dahlem Junior MA; Aix-Marseille Université, CNRS, CINaM, 13009 Marseille, France.
Nguema Edzang RW; Aix-Marseille Université, CNRS, CINaM, 13009 Marseille, France.; Department of Chemistry and Biochemistry, University of Health Science (USS), Libreville 18231, Gabon.
Catto AL; Aix-Marseille Université, CNRS, CINaM, 13009 Marseille, France.; Center for Exact and Technological Sciences (CETEC), University of Taquari Valley, Lajeado 95914-014, RS, Brazil.
Raimundo JM; Aix-Marseille Université, CNRS, CINaM, 13009 Marseille, France.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Nov 15; Vol. 23 (22). Date of Electronic Publication: 2022 Nov 15.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Antifungal Agents*
Quinones*/pharmacology
Anti-Bacterial Agents/pharmacology ; Biofilms

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Skocz do pozycji: 7.

Tytuł:: A 3D-Predicted Structure of the Amine Oxidase Domain of Lysyl Oxidase-Like 2.
Autorzy:: Meier AA; Department of Chemistry, The University of Kansas, Lawrence, KS 66045, USA.
Kuczera K; Department of Chemistry, The University of Kansas, Lawrence, KS 66045, USA.; Department of Molecular Biosciences, University of Kansas, Lawrence, KS 66045, USA.
Mure M; Department of Chemistry, The University of Kansas, Lawrence, KS 66045, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Nov 02; Vol. 23 (21). Date of Electronic Publication: 2022 Nov 02.
Typ publikacji:: Journal Article
MeSH Terms:: Protein-Lysine 6-Oxidase*/chemistry
Quinones*/chemistry
Models, Molecular ; Monoamine Oxidase ; Amines ; Amino Acid Oxidoreductases/chemistry

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Skocz do pozycji: 8.

Tytuł:: Construction of C-N Atropisomers by Aminocatalytic Enantioselective Addition of Indole-2-carboxaldehydes to o-Quinone Derivatives.
Autorzy:: Corti V; Department of Chemistry, Aarhus University, Aarhus, 8000 Aarhus C, Denmark.
Thøgersen MK; Department of Chemistry, Aarhus University, Aarhus, 8000 Aarhus C, Denmark.
Enemaerke VJ; Department of Chemistry, Aarhus University, Aarhus, 8000 Aarhus C, Denmark.
Rezayee NM; Department of Chemistry, Aarhus University, Aarhus, 8000 Aarhus C, Denmark.
Barløse CL; Department of Chemistry, Aarhus University, Aarhus, 8000 Aarhus C, Denmark.
Anker Jørgensen K; Department of Chemistry, Aarhus University, Aarhus, 8000 Aarhus C, Denmark.; Pokaż więcej
Źródło:: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2022 Oct 26; Vol. 28 (60), pp. e202202395. Date of Electronic Publication: 2022 Aug 23.
Typ publikacji:: Journal Article
MeSH Terms:: Indoles*/chemistry
Quinones*
Stereoisomerism ; Amines/chemistry ; Complex Mixtures

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Skocz do pozycji: 9.

Tytuł:: Bridging population pharmacokinetic and semimechanistic absorption modeling of APX3330.
Autorzy:: Silva LL; Division of Clinical Pharmacology, Department of Medicine, Indiana University School of Medicine, Indiana, Indianapolis, USA.
Stratford RE; Division of Clinical Pharmacology, Department of Medicine, Indiana University School of Medicine, Indiana, Indianapolis, USA.
Messmann R; Apexian Pharmaceuticals, Indianapolis, Indiana, USA.
Kelley MR; Departments of Biochemistry and Molecular Biology, and Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Indiana University Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Quinney SK; Division of Clinical Pharmacology, Department of Medicine, Indiana University School of Medicine, Indiana, Indianapolis, USA.; Indiana University Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Department of Obstetrics and Gynecology, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Pokaż więcej
Źródło:: CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2024 Jan; Vol. 13 (1), pp. 106-117. Date of Electronic Publication: 2023 Oct 26.
Typ publikacji:: Journal Article
MeSH Terms:: Hydroquinones*
Neoplasms*
Humans ; Male ; Administration, Oral ; Angiogenesis Inhibitors ; Quinones

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Skocz do pozycji: 10.

Tytuł:: Oxidation of Mesalamine under Phenoloxidase- or Peroxidase-like Enzyme Catalysis.
Autorzy:: El Zein R; Department of Chemistry and Center CERMO-FC, Université du Québec à Montréal, Downtown Branch, P.O. Box 8888, Montréal, QC H3C 3P8, Canada.
Ispas-Szabo P; Department of Chemistry and Center CERMO-FC, Université du Québec à Montréal, Downtown Branch, P.O. Box 8888, Montréal, QC H3C 3P8, Canada.
Jafari M; Department of Chemistry and Center CERMO-FC, Université du Québec à Montréal, Downtown Branch, P.O. Box 8888, Montréal, QC H3C 3P8, Canada.
Siaj M; Department of Chemistry and Center CERMO-FC, Université du Québec à Montréal, Downtown Branch, P.O. Box 8888, Montréal, QC H3C 3P8, Canada.
Mateescu MA; Department of Chemistry and Center CERMO-FC, Université du Québec à Montréal, Downtown Branch, P.O. Box 8888, Montréal, QC H3C 3P8, Canada.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Dec 15; Vol. 28 (24). Date of Electronic Publication: 2023 Dec 15.
Typ publikacji:: Journal Article
MeSH Terms:: Mesalamine*/chemistry
Colitis, Ulcerative*/drug therapy
Humans ; Monophenol Monooxygenase ; Hydroquinones ; Anti-Inflammatory Agents, Non-Steroidal/chemistry ; Peroxidase ; Oxidation-Reduction ; Peroxidases ; Quinones/therapeutic use ; Catalysis ; Imines

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