Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""Réplication"" wg kryterium: Temat


Tytuł :
Replication timing maintains the global epigenetic state in human cells.
Autorzy :
Klein KN; Department of Biological Science, Florida State University, Tallahassee, FL 32306, USA.
Zhao PA; Department of Biological Science, Florida State University, Tallahassee, FL 32306, USA.
Lyu X; Department of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322, USA.; State Key Laboratory of Cellular Stress Biology, Fujian Provincial Key Laboratory of Reproductive Health Research, School of Medicine, Xiamen University, Xiamen, China.
Sasaki T; Department of Biological Science, Florida State University, Tallahassee, FL 32306, USA.; San Diego Biomedical Research Institute, La Jolla, CA 92121, USA.
Bartlett DA; Department of Biological Science, Florida State University, Tallahassee, FL 32306, USA.
Singh AM; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602, USA.
Tasan I; Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Zhang M; Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Watts LP; Institute of Medical Sciences, University of Aberdeen, Aberdeen AB25 2ZD, UK.
Hiraga SI; Institute of Medical Sciences, University of Aberdeen, Aberdeen AB25 2ZD, UK.
Natsume T; Department of Chromosome Science, National Institute of Genetics, Research Organization of Information and Systems (ROIS), Yata 1111, Mishima, Shizuoka 411-8540, Japan.; Department of Genetics, The Graduate University for Advanced Studies (SOKENDAI), Yata 1111, Mishima, Shizuoka 411-8540, Japan.
Zhou X; Division of Life Science, Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China.
Baslan T; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Leung D; Division of Life Science, Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China.
Kanemaki MT; Department of Chromosome Science, National Institute of Genetics, Research Organization of Information and Systems (ROIS), Yata 1111, Mishima, Shizuoka 411-8540, Japan.; Department of Genetics, The Graduate University for Advanced Studies (SOKENDAI), Yata 1111, Mishima, Shizuoka 411-8540, Japan.
Donaldson AD; Institute of Medical Sciences, University of Aberdeen, Aberdeen AB25 2ZD, UK.
Zhao H; Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Dalton S; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA 30602, USA.
Corces VG; Department of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322, USA.
Gilbert DM; Department of Biological Science, Florida State University, Tallahassee, FL 32306, USA. .; San Diego Biomedical Research Institute, La Jolla, CA 92121, USA.
Pokaż więcej
Źródło :
Science (New York, N.Y.) [Science] 2021 Apr 23; Vol. 372 (6540), pp. 371-378. Date of Electronic Publication: 2021 Apr 22.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Replication Timing*
Epigenesis, Genetic*
Epigenome*
Telomere-Binding Proteins/*metabolism
Cell Line ; Chromatin/metabolism ; Chromatin Assembly and Disassembly ; DNA Replication ; Gene Expression ; Gene Knockout Techniques ; Genome, Human ; Heterochromatin/metabolism ; Histone Code ; Histones/metabolism ; Humans ; Telomere-Binding Proteins/genetics
Czasopismo naukowe
Tytuł :
G-quadruplex binding protein Rif1, a key regulator of replication timing.
Autorzy :
Alavi S; Department of Nanobiotechnology.
Ghadiri H; Department of Biochemistry, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran.
Dabirmanesh B; Department of Biochemistry, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran.
Moriyama K; Genome Dynamics Project, Department of Basic Medical Sciences, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa, Setagaya-ku, Tokyo, Japan.
Khajeh K; Department of Nanobiotechnology.; Department of Biochemistry, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran.
Masai H; Genome Dynamics Project, Department of Basic Medical Sciences, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa, Setagaya-ku, Tokyo, Japan.
Pokaż więcej
Źródło :
Journal of biochemistry [J Biochem] 2021 Feb 06; Vol. 169 (1), pp. 1-14.
Typ publikacji :
Journal Article; Review
MeSH Terms :
DNA Replication Timing*
G-Quadruplexes*
Telomere-Binding Proteins/*metabolism
Animals ; Carrier Proteins/genetics ; Carrier Proteins/metabolism ; Cell Cycle ; Cell Nucleus/metabolism ; Chromatin/genetics ; Chromatin/metabolism ; DNA Replication ; Humans ; Protein Binding/genetics ; Repressor Proteins/genetics ; Repressor Proteins/metabolism ; S Phase ; Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/metabolism ; Schizosaccharomyces/metabolism ; Schizosaccharomyces pombe Proteins/genetics ; Schizosaccharomyces pombe Proteins/metabolism ; Telomere-Binding Proteins/genetics
Czasopismo naukowe
Tytuł :
RPA complexes in Caenorhabditis elegans meiosis; unique roles in replication, meiotic recombination and apoptosis.
Autorzy :
Hefel A; Department of Biology, The University of Iowa, Iowa City, IA 52242, USA.
Honda M; Department of Biochemistry, The University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.
Cronin N; Department of Biochemistry, The University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.
Harrell K; Department of Biology, The University of Iowa, Iowa City, IA 52242, USA.
Patel P; Department of Biology, The University of Iowa, Iowa City, IA 52242, USA.
Spies M; Department of Biochemistry, The University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.
Smolikove S; Department of Biology, The University of Iowa, Iowa City, IA 52242, USA.
Pokaż więcej
Źródło :
Nucleic acids research [Nucleic Acids Res] 2021 Feb 26; Vol. 49 (4), pp. 2005-2026.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Apoptosis*
DNA Replication*
Recombination, Genetic*
Caenorhabditis elegans/*genetics
Caenorhabditis elegans Proteins/*physiology
Meiosis/*genetics
Replication Protein A/*physiology
Animals ; Caenorhabditis elegans Proteins/analysis ; Caenorhabditis elegans Proteins/metabolism ; DNA Breaks, Double-Stranded ; Mitosis/genetics ; Rad51 Recombinase/analysis ; Replication Protein A/metabolism
Czasopismo naukowe
Tytuł :
The ESCRT-I Subunit Tsg101 Plays Novel Dual Roles in Entry and Replication of Classical Swine Fever Virus.
Autorzy :
Liu CC; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.
Liu YY; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.
Cheng Y; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.
Zhang YN; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.
Zhang J; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.
Liang XD; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.
Gao Y; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.
Chen H; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.
Baloch AS; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.
Yang Q; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.
Go YY; Department of Infectious Diseases and Public Health, City University of Hong Kong, Hong Kong SAR, China.
Zhou B; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China .
Pokaż więcej
Źródło :
Journal of virology [J Virol] 2021 Feb 24; Vol. 95 (6). Date of Electronic Publication: 2021 Feb 24 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Virus Internalization*
Virus Replication*
Classical Swine Fever Virus/*physiology
DNA-Binding Proteins/*metabolism
Endosomal Sorting Complexes Required for Transport/*metabolism
Transcription Factors/*metabolism
Animals ; Cell Line ; Classical Swine Fever/metabolism ; Classical Swine Fever/virology ; DNA-Binding Proteins/genetics ; Endoplasmic Reticulum/metabolism ; Endoplasmic Reticulum/virology ; Endosomal Sorting Complexes Required for Transport/genetics ; Endosomes/metabolism ; Endosomes/virology ; Host-Pathogen Interactions ; Lysosomes/metabolism ; Lysosomes/virology ; RNA, Viral/metabolism ; Swine ; Transcription Factors/genetics ; Viral Nonstructural Proteins/metabolism ; Viral Replication Compartments/metabolism
Czasopismo naukowe
Tytuł :
Clustering of strong replicators associated with active promoters is sufficient to establish an early-replicating domain.
Autorzy :
Brossas C; CNRS, Institut Jacques Monod, Equipe Labellisée Association Pour la Recherche sur le Cancer, Université de Paris, Paris, France.
Valton AL; Department of Biochemistry and Molecular Pharmacology, Program in Systems Biology, University of Massachusetts Medical School, Worcester, MA, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, USA.
Venev SV; Department of Biochemistry and Molecular Pharmacology, Program in Systems Biology, University of Massachusetts Medical School, Worcester, MA, USA.
Chilaka S; Centre for Immunology, University of Glasgow, Glasgow, UK.
Counillon A; CNRS, Institut Jacques Monod, Equipe Labellisée Association Pour la Recherche sur le Cancer, Université de Paris, Paris, France.
Laurent M; CNRS, Institut Jacques Monod, Equipe Labellisée Association Pour la Recherche sur le Cancer, Université de Paris, Paris, France.
Goncalves C; CNRS, Institut Jacques Monod, Equipe Labellisée Association Pour la Recherche sur le Cancer, Université de Paris, Paris, France.
Duriez B; CNRS, Institut Jacques Monod, Equipe Labellisée Association Pour la Recherche sur le Cancer, Université de Paris, Paris, France.
Picard F; Laboratoire de Biométrie et Biologie Evolutive UMR 5558, CNRS, Université de Lyon, Université Lyon 1, Villeurbanne, France.
Dekker J; Department of Biochemistry and Molecular Pharmacology, Program in Systems Biology, University of Massachusetts Medical School, Worcester, MA, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, USA.
Prioleau MN; CNRS, Institut Jacques Monod, Equipe Labellisée Association Pour la Recherche sur le Cancer, Université de Paris, Paris, France.
Pokaż więcej
Źródło :
The EMBO journal [EMBO J] 2020 Nov 02; Vol. 39 (21), pp. e99520. Date of Electronic Publication: 2020 Sep 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Replication*
DNA Replication Timing*
Promoter Regions, Genetic*
Actins/genetics ; Binding Sites ; Chromatin ; Chromosomes ; Cluster Analysis ; Epigenomics ; Humans ; Replication Origin ; beta-Globins/genetics
Czasopismo naukowe
Tytuł :
Dynamic elements of replication protein A at the crossroads of DNA replication, recombination, and repair.
Autorzy :
Caldwell CC; Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Spies M; Department of Biochemistry, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Pokaż więcej
Źródło :
Critical reviews in biochemistry and molecular biology [Crit Rev Biochem Mol Biol] 2020 Oct; Vol. 55 (5), pp. 482-507. Date of Electronic Publication: 2020 Aug 28.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Review
MeSH Terms :
DNA Repair*
DNA Replication*
Recombination, Genetic*
Eukaryota/*metabolism
Replication Protein A/*metabolism
Animals ; DNA, Single-Stranded/metabolism ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/metabolism ; Eukaryota/genetics ; Humans ; Protein Conformation ; Replication Protein A/genetics
Czasopismo naukowe
Tytuł :
Coronavirus infection induces progressive restructuring of the endoplasmic reticulum involving the formation and degradation of double membrane vesicles.
Autorzy :
Mihelc EM; Department of Biological Sciences, Purdue University, 915 W. State St. West Lafayette, IN, 47907, USA. Electronic address: .
Baker SC; Department of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicago, 2160 South First Ave. Maywood, IL, 60153, USA.
Lanman JK; Department of Biological Sciences, Purdue University, 915 W. State St. West Lafayette, IN, 47907, USA.
Pokaż więcej
Źródło :
Virology [Virology] 2021 Apr; Vol. 556, pp. 9-22. Date of Electronic Publication: 2020 Dec 24.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Coronavirus Infections/*virology
Endoplasmic Reticulum/*metabolism
Murine hepatitis virus/*physiology
Viral Replication Compartments/*metabolism
Animals ; Cell Line ; Electron Microscope Tomography ; Endoplasmic Reticulum/ultrastructure ; Endoplasmic Reticulum/virology ; Lysosomes/metabolism ; Lysosomes/ultrastructure ; Lysosomes/virology ; Mice ; Viral Proteins/metabolism ; Viral Replication Compartments/ultrastructure ; Virion/metabolism ; Virus Assembly ; Virus Replication
Czasopismo naukowe
Tytuł :
Pif1, RPA, and FEN1 modulate the ability of DNA polymerase δ to overcome protein barriers during DNA synthesis.
Autorzy :
Sparks MA; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, Missouri USA.
Burgers PM; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, Missouri USA. Electronic address: .
Galletto R; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, Missouri USA. Electronic address: .
Pokaż więcej
Źródło :
The Journal of biological chemistry [J Biol Chem] 2020 Nov 20; Vol. 295 (47), pp. 15883-15891. Date of Electronic Publication: 2020 Sep 10.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
DNA Replication*
Acetyltransferases/*metabolism
DNA Helicases/*metabolism
DNA Polymerase III/*metabolism
DNA, Fungal/*biosynthesis
Membrane Proteins/*metabolism
Replication Protein A/*metabolism
Saccharomyces cerevisiae/*metabolism
Saccharomyces cerevisiae Proteins/*metabolism
Acetyltransferases/genetics ; DNA Helicases/genetics ; DNA Polymerase III/genetics ; DNA, Fungal/genetics ; Membrane Proteins/genetics ; Replication Protein A/genetics ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae Proteins/genetics
Czasopismo naukowe
Tytuł :
RPA2 winged-helix domain facilitates UNG-mediated removal of uracil from ssDNA; implications for repair of mutagenic uracil at the replication fork.
Autorzy :
Kavli B; Department of Clinical and Molecular Medicine, NTNU Norwegian University of Science and Technology, NO-7491 Trondheim, Norway.; Clinic of Laboratory Medicine, St. Olavs Hospital, Trondheim University Hospital, NO-7006 Trondheim, Norway.
Iveland TS; Department of Clinical and Molecular Medicine, NTNU Norwegian University of Science and Technology, NO-7491 Trondheim, Norway.; Cancer Clinic, St. Olavs Hospital, Trondheim University Hospital, NO-7006 Trondheim, Norway.
Buchinger E; NOBIPOL, Department of Biotechnology and Food Science, NTNU Norwegian University of Science and Technology, N-7034 Trondheim, Norway.
Hagen L; Department of Clinical and Molecular Medicine, NTNU Norwegian University of Science and Technology, NO-7491 Trondheim, Norway.; Clinic of Laboratory Medicine, St. Olavs Hospital, Trondheim University Hospital, NO-7006 Trondheim, Norway.; PROMEC Proteomics and Modomics Experimental Core at NTNU and the Central Norway Regional Health Authority, NO-7491 Trondheim, Norway.
Liabakk NB; Department of Clinical and Molecular Medicine, NTNU Norwegian University of Science and Technology, NO-7491 Trondheim, Norway.; Clinic of Laboratory Medicine, St. Olavs Hospital, Trondheim University Hospital, NO-7006 Trondheim, Norway.
Aas PA; Department of Clinical and Molecular Medicine, NTNU Norwegian University of Science and Technology, NO-7491 Trondheim, Norway.; Clinic of Laboratory Medicine, St. Olavs Hospital, Trondheim University Hospital, NO-7006 Trondheim, Norway.
Obermann TS; Department of Clinical and Molecular Medicine, NTNU Norwegian University of Science and Technology, NO-7491 Trondheim, Norway.; Clinic of Laboratory Medicine, St. Olavs Hospital, Trondheim University Hospital, NO-7006 Trondheim, Norway.
Aachmann FL; NOBIPOL, Department of Biotechnology and Food Science, NTNU Norwegian University of Science and Technology, N-7034 Trondheim, Norway.
Slupphaug G; Department of Clinical and Molecular Medicine, NTNU Norwegian University of Science and Technology, NO-7491 Trondheim, Norway.; Clinic of Laboratory Medicine, St. Olavs Hospital, Trondheim University Hospital, NO-7006 Trondheim, Norway.; PROMEC Proteomics and Modomics Experimental Core at NTNU and the Central Norway Regional Health Authority, NO-7491 Trondheim, Norway.
Pokaż więcej
Źródło :
Nucleic acids research [Nucleic Acids Res] 2021 Apr 19; Vol. 49 (7), pp. 3948-3966.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Replication*
DNA Glycosylases/*metabolism
DNA, Single-Stranded/*metabolism
Replication Protein A/*metabolism
Uracil/*metabolism
Binding Sites ; Humans ; Protein Binding ; Recombinant Proteins/metabolism
Czasopismo naukowe
Tytuł :
DOCK7 protects against replication stress by promoting RPA stability on chromatin.
Autorzy :
Gao M; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA.; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.
Guo G; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA.; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.
Huang J; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA.; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.
Hou X; Department of Medical Oncology, Mayo Clinic, Rochester, MN 55905, USA.
Ham H; Department of Biochemistry and Molecular Biology, Division of Oncology Research, Mayo Clinic, Rochester, MN 55905, USA.
Kim W; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA.; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.
Zhao F; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA.; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.
Tu X; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA.; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.
Zhou Q; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA.; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.
Zhang C; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA.; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.
Zhu Q; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA.; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.
Liu J; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA.; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.
Yan Y; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA.; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.
Xu Z; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA.; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.
Yin P; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA.; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.
Luo K; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA.; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.
Weroha J; Department of Medical Oncology, Mayo Clinic, Rochester, MN 55905, USA.
Deng M; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA.; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.
Billadeau DD; Department of Biochemistry and Molecular Biology, Division of Oncology Research, Mayo Clinic, Rochester, MN 55905, USA.
Lou Z; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA.; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.
Pokaż więcej
Źródło :
Nucleic acids research [Nucleic Acids Res] 2021 Apr 06; Vol. 49 (6), pp. 3322-3337.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Replication*
Chromatin/*metabolism
GTPase-Activating Proteins/*physiology
Guanine Nucleotide Exchange Factors/*physiology
Replication Protein A/*metabolism
Animals ; Cell Line, Tumor ; DNA Repair ; Female ; GTPase-Activating Proteins/antagonists & inhibitors ; GTPase-Activating Proteins/metabolism ; Guanine Nucleotide Exchange Factors/antagonists & inhibitors ; Guanine Nucleotide Exchange Factors/metabolism ; HEK293 Cells ; Humans ; Mice ; Mice, Nude ; Ovarian Neoplasms/drug therapy ; Ovarian Neoplasms/metabolism ; Phosphorylation ; Proteolysis ; Signal Transduction ; Stress, Physiological/genetics ; cdc42 GTP-Binding Protein/metabolism ; p21-Activated Kinases/metabolism ; rac1 GTP-Binding Protein/metabolism
Czasopismo naukowe
Tytuł :
Interactions of replication initiator RctB with single- and double-stranded DNA in origin opening of Vibrio cholerae chromosome 2.
Autorzy :
Chatterjee S; Basic Research Laboratory, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892-4260, USA.
Jha JK; Basic Research Laboratory, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892-4260, USA.
Ciaccia P; Basic Research Laboratory, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892-4260, USA.
Venkova T; Basic Research Laboratory, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892-4260, USA.
Chattoraj DK; Basic Research Laboratory, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892-4260, USA.
Pokaż więcej
Źródło :
Nucleic acids research [Nucleic Acids Res] 2020 Nov 04; Vol. 48 (19), pp. 11016-11029.
Typ publikacji :
Journal Article; Research Support, N.I.H., Intramural
MeSH Terms :
DNA Replication*
Bacterial Proteins/*metabolism
Chromosomes, Bacterial/*metabolism
DNA Helicases/*metabolism
DNA, Bacterial/*metabolism
DNA-Binding Proteins/*metabolism
Trans-Activators/*metabolism
Vibrio cholerae/*genetics
Binding Sites ; Gene Expression Regulation, Bacterial ; Protein Binding ; Replication Origin
Czasopismo naukowe
Tytuł :
The retromer is co-opted to deliver lipid enzymes for the biogenesis of lipid-enriched tombusviral replication organelles.
Autorzy :
Feng Z; Department of Plant Pathology, University of Kentucky, Lexington, KY 40546.
Inaba JI; Department of Plant Pathology, University of Kentucky, Lexington, KY 40546.
Nagy PD; Department of Plant Pathology, University of Kentucky, Lexington, KY 40546 .
Pokaż więcej
Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Jan 05; Vol. 118 (1).
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Vesicular Transport Proteins/*metabolism
Virus Replication/*physiology
Class III Phosphatidylinositol 3-Kinases/metabolism ; Endosomal Sorting Complexes Required for Transport/metabolism ; Host-Pathogen Interactions/genetics ; Lipid Metabolism/physiology ; Lipids/physiology ; Peroxisomes/metabolism ; Phosphatidylinositol Phosphates/metabolism ; Phosphatidylinositols/metabolism ; RNA, Viral/genetics ; Saccharomyces cerevisiae/metabolism ; Saccharomyces cerevisiae Proteins/metabolism ; Tombusvirus/genetics ; Tombusvirus/metabolism ; Viral Proteins/metabolism ; Viral Replication Compartments/metabolism ; Viral Replication Compartments/physiology
Czasopismo naukowe
Tytuł :
Generation of Fluorescent Versions of Saccharomyces cerevisiae RPA to Study the Conformational Dynamics of Its ssDNA-Binding Domains.
Autorzy :
Kuppa S; Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, MO, USA.
Pokhrel N; Department of Biological Sciences, Marquette University, Milwaukee, WI, USA.; New England Biolabs, Ipswich, MA, USA.
Corless E; Department of Biological Sciences, Marquette University, Milwaukee, WI, USA.
Origanti S; Department of Biology, Saint Louis University, St. Louis, MO, USA.
Antony E; Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, MO, USA. .
Pokaż więcej
Źródło :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2281, pp. 151-168.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Azides/*chemical synthesis
DNA, Single-Stranded/*metabolism
Phenylalanine/*analogs & derivatives
Replication Protein A/*chemistry
Replication Protein A/*metabolism
Saccharomyces cerevisiae/*metabolism
Saccharomyces cerevisiae Proteins/*chemistry
Saccharomyces cerevisiae Proteins/*metabolism
Azides/chemistry ; DNA Replication ; Fluorescent Dyes/chemistry ; Models, Molecular ; Phenylalanine/chemical synthesis ; Phenylalanine/chemistry ; Protein Binding ; Protein Conformation ; Protein Domains
Czasopismo naukowe
Tytuł :
CDC7 kinase promotes MRE11 fork processing, modulating fork speed and chromosomal breakage.
Autorzy :
Rainey MD; Centre for Chromosome Biology, School of Natural Sciences, National University of Ireland Galway, Galway, Ireland.
Quinlan A; Centre for Chromosome Biology, School of Natural Sciences, National University of Ireland Galway, Galway, Ireland.
Cazzaniga C; Centre for Chromosome Biology, School of Natural Sciences, National University of Ireland Galway, Galway, Ireland.
Mijic S; Institute of Molecular Cancer Research, University of Zurich, Zurich, Switzerland.
Martella O; Centre for Chromosome Biology, School of Natural Sciences, National University of Ireland Galway, Galway, Ireland.
Krietsch J; Institute of Molecular Cancer Research, University of Zurich, Zurich, Switzerland.
Göder A; Centre for Chromosome Biology, School of Natural Sciences, National University of Ireland Galway, Galway, Ireland.
Lopes M; Institute of Molecular Cancer Research, University of Zurich, Zurich, Switzerland.
Santocanale C; Centre for Chromosome Biology, School of Natural Sciences, National University of Ireland Galway, Galway, Ireland.
Pokaż więcej
Źródło :
EMBO reports [EMBO Rep] 2020 Aug 05; Vol. 21 (8), pp. e48920. Date of Electronic Publication: 2020 Jun 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chromosome Breakage*
DNA Replication*
Cell Cycle Proteins/genetics ; Cell Cycle Proteins/metabolism ; Humans ; Phosphorylation ; Protein-Serine-Threonine Kinases/metabolism ; Replication Origin/genetics
Czasopismo naukowe
Tytuł :
Phosphatidylinositol 3-Phosphate Mediates the Establishment of Infectious Bursal Disease Virus Replication Complexes in Association with Early Endosomes.
Autorzy :
Gimenez MC; Department of Biological Sciences and Department of Cell and System Biology, University of Toronto at Scarborough, Scarborough, Canada.; IHEM, Universidad Nacional de Cuyo, CONICET, Facultad de Ciencias Médicas, Mendoza, Argentina.
Issa M; Department of Biological Sciences and Department of Cell and System Biology, University of Toronto at Scarborough, Scarborough, Canada.
Sheth J; Department of Biological Sciences and Department of Cell and System Biology, University of Toronto at Scarborough, Scarborough, Canada.
Colombo MI; IHEM, Universidad Nacional de Cuyo, CONICET, Facultad de Ciencias Médicas, Mendoza, Argentina.
Terebiznik MR; Department of Biological Sciences and Department of Cell and System Biology, University of Toronto at Scarborough, Scarborough, Canada .
Delgui LR; Facultad de Ciencias Exactas y Naturales, Universidad Nacional de Cuyo, Mendoza, Argentina .; IHEM, Universidad Nacional de Cuyo, CONICET, Facultad de Ciencias Médicas, Mendoza, Argentina.
Pokaż więcej
Źródło :
Journal of virology [J Virol] 2021 Feb 24; Vol. 95 (6). Date of Electronic Publication: 2021 Feb 24 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Endosomes/*metabolism
Infectious bursal disease virus/*physiology
Phosphatidylinositol Phosphates/*metabolism
Viral Replication Compartments/*metabolism
Animals ; Cell Line ; Endosomes/virology ; Intracellular Membranes/metabolism ; Quail ; Viral Structural Proteins/metabolism ; Virus Replication
Czasopismo naukowe
Tytuł :
Heat Shock Protein 90 Chaperones E1A Early Protein of Adenovirus 5 and Is Essential for Replication of the Virus.
Autorzy :
Dalidowska I; Department of Experimental Pharmacology, Mossakowski Medical Research Institute, Polish Academy of Sciences, Pawinskiego 5, 02-106 Warsaw, Poland.
Gazi O; Chair and Department of Medical Microbiology, Medical University of Warsaw, 02-091 Warsaw, Poland.
Sulejczak D; Department of Experimental Pharmacology, Mossakowski Medical Research Institute, Polish Academy of Sciences, Pawinskiego 5, 02-106 Warsaw, Poland.
Przybylski M; Chair and Department of Medical Microbiology, Medical University of Warsaw, 02-091 Warsaw, Poland.
Bieganowski P; Department of Experimental Pharmacology, Mossakowski Medical Research Institute, Polish Academy of Sciences, Pawinskiego 5, 02-106 Warsaw, Poland.
Pokaż więcej
Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Feb 18; Vol. 22 (4). Date of Electronic Publication: 2021 Feb 18.
Typ publikacji :
Journal Article
MeSH Terms :
Adenoviridae/*physiology
Adenovirus E1A Proteins/*metabolism
HSP90 Heat-Shock Proteins/*metabolism
Virus Replication/*physiology
A549 Cells ; Adenoviridae/drug effects ; Adenoviridae/genetics ; Benzoquinones/pharmacology ; DNA Replication/drug effects ; HEK293 Cells ; HSP90 Heat-Shock Proteins/antagonists & inhibitors ; Humans ; Lactams, Macrocyclic/pharmacology ; Protein Binding/drug effects ; Proteolysis/drug effects ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Receptors, Virus/metabolism ; Transcription, Genetic/drug effects ; Virus Replication/genetics
Czasopismo naukowe
Tytuł :
The Bloom syndrome complex senses RPA-coated single-stranded DNA to restart stalled replication forks.
Autorzy :
Shorrocks AK; MRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DS, UK.; MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, OX3 7DQ, UK.
Jones SE; MRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DS, UK.; MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, OX3 7DQ, UK.
Tsukada K; MRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DS, UK.; MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, OX3 7DQ, UK.; Department of Transdisciplinary Science and Engineering, School of Environment and Society, Tokyo Institute of Technology, Tokyo, 152-8550, Japan.
Morrow CA; MRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DS, UK.; MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, OX3 7DQ, UK.
Belblidia Z; MRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DS, UK.; MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, OX3 7DQ, UK.
Shen J; MRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DS, UK.; MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, OX3 7DQ, UK.; Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT, 06520, USA.
Vendrell I; MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, OX3 7DQ, UK.; Target Discovery Institute, Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7FZ, UK.
Fischer R; Target Discovery Institute, Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7FZ, UK.
Kessler BM; Target Discovery Institute, Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7FZ, UK.
Blackford AN; MRC Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DS, UK. .; MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, OX3 7DQ, UK. .
Pokaż więcej
Źródło :
Nature communications [Nat Commun] 2021 Jan 26; Vol. 12 (1), pp. 585. Date of Electronic Publication: 2021 Jan 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Replication*
Bloom Syndrome/*genetics
DNA, Single-Stranded/*metabolism
RecQ Helicases/*metabolism
Replication Protein A/*metabolism
Amino Acid Motifs/genetics ; CRISPR-Cas Systems/genetics ; DNA Damage ; DNA Topoisomerases, Type I/metabolism ; DNA, Single-Stranded/genetics ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/metabolism ; Gene Knockdown Techniques ; HeLa Cells ; Humans ; Mitosis/genetics ; Mutation ; Protein Binding/genetics ; Protein Domains/genetics ; RecQ Helicases/genetics ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Recombinational DNA Repair/genetics
Czasopismo naukowe
Tytuł :
APOBEC1 cytosine deaminase activity on single-stranded DNA is suppressed by replication protein A.
Autorzy :
Wong L; Department of Biochemistry, Microbiology, and Immunology, University of Saskatchewan, Saskatoon, Saskatchewan S7N 5E5, Canada.
Vizeacoumar FS; Department of Pathology and Laboratory Medicine, College of Medicine, University of Saskatchewan, Saskatoon S7N 5E5, Canada.
Vizeacoumar FJ; Department of Pathology and Laboratory Medicine, College of Medicine, University of Saskatchewan, Saskatoon S7N 5E5, Canada.; Cancer Research, Saskatchewan Cancer Agency, Saskatoon, Saskatchewan S7S 0A6, Canada.
Chelico L; Department of Biochemistry, Microbiology, and Immunology, University of Saskatchewan, Saskatoon, Saskatchewan S7N 5E5, Canada.
Pokaż więcej
Źródło :
Nucleic acids research [Nucleic Acids Res] 2021 Jan 11; Vol. 49 (1), pp. 322-339.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
APOBEC-1 Deaminase/*antagonists & inhibitors
DNA, Single-Stranded/*metabolism
Neoplasm Proteins/*metabolism
Replication Protein A/*metabolism
APOBEC-1 Deaminase/metabolism ; Binding, Competitive ; Cell Line ; Cell Line, Tumor ; Cytidine/metabolism ; DNA Damage ; DNA Replication ; DNA, Neoplasm/chemistry ; DNA, Neoplasm/metabolism ; DNA, Single-Stranded/chemistry ; Deamination ; Facilitated Diffusion ; Histones/analysis ; Humans ; Lung/cytology ; Lung/embryology ; Neoplasm Proteins/antagonists & inhibitors ; Neoplasms/genetics ; Neoplasms/pathology ; Organ Specificity ; RNA, Messenger/biosynthesis ; RNA, Messenger/genetics ; RNA, Neoplasm/biosynthesis ; RNA, Neoplasm/genetics ; Recombinant Fusion Proteins/metabolism ; Replication Protein A/genetics
Czasopismo naukowe
Tytuł :
Japanese encephalitis virus capsid protein interacts with non-lipidated MAP1LC3 on replication membranes and lipid droplets.
Autorzy :
Sarkar R; Translational Health Science & Technology Institute, NCR Biotech Science Cluster, Faridabad, Haryana, India.
Sharma KB; Regional Centre for Biotechnology, NCR Biotech Science Cluster, Faridabad, Haryana, India.; Translational Health Science & Technology Institute, NCR Biotech Science Cluster, Faridabad, Haryana, India.
Kumari A; Translational Health Science & Technology Institute, NCR Biotech Science Cluster, Faridabad, Haryana, India.
Asthana S; Translational Health Science & Technology Institute, NCR Biotech Science Cluster, Faridabad, Haryana, India.
Kalia M; Translational Health Science & Technology Institute, NCR Biotech Science Cluster, Faridabad, Haryana, India.; Regional Centre for Biotechnology, NCR Biotech Science Cluster, Faridabad, Haryana, India.
Pokaż więcej
Źródło :
The Journal of general virology [J Gen Virol] 2021 Jan; Vol. 102 (1). Date of Electronic Publication: 2020 Oct 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Capsid Proteins/*metabolism
Encephalitis Virus, Japanese/*physiology
Lipid Droplets/*metabolism
Microtubule-Associated Proteins/*metabolism
Viral Replication Compartments/*metabolism
Amino Acid Sequence ; Animals ; Capsid/chemistry ; Capsid/metabolism ; Capsid Proteins/chemistry ; Cell Line ; Encephalitis Virus, Japanese/metabolism ; Host-Pathogen Interactions ; Humans ; Mice ; Molecular Docking Simulation ; Protein Interaction Domains and Motifs ; Virus Replication
Czasopismo naukowe
Tytuł :
Replicative aging is associated with loss of genetic heterogeneity from extrachromosomal circular DNA in Saccharomyces cerevisiae.
Autorzy :
Prada-Luengo I; Ecology and Evolution, Department of Biology, University of Copenhagen, Copenhagen DK-2100, Denmark.
Møller HD; Ecology and Evolution, Department of Biology, University of Copenhagen, Copenhagen DK-2100, Denmark.; Department of Biology, Institute of Biochemistry, ETH Zürich, Zurich CH-8093, Switzerland.
Henriksen RA; Ecology and Evolution, Department of Biology, University of Copenhagen, Copenhagen DK-2100, Denmark.
Gao Q; Epigenetics Programme, The Babraham Institute, Babraham, Cambridge CB22 3-AT, UK.; Adaptimmune Ltd, Oxfordshire OX14 4RX, UK.
Larsen CE; Ecology and Evolution, Department of Biology, University of Copenhagen, Copenhagen DK-2100, Denmark.
Alizadeh S; Ecology and Evolution, Department of Biology, University of Copenhagen, Copenhagen DK-2100, Denmark.
Maretty L; Department of Molecular Medicine, Aarhus University Hospital, Aarhus DK-8200, Denmark.
Houseley J; Epigenetics Programme, The Babraham Institute, Babraham, Cambridge CB22 3-AT, UK.
Regenberg B; Ecology and Evolution, Department of Biology, University of Copenhagen, Copenhagen DK-2100, Denmark.
Pokaż więcej
Źródło :
Nucleic acids research [Nucleic Acids Res] 2020 Aug 20; Vol. 48 (14), pp. 7883-7898.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Replication*
Cellular Senescence/*genetics
DNA, Circular/*chemistry
Saccharomyces cerevisiae/*genetics
DNA, Circular/analysis ; Genetic Variation ; Inheritance Patterns ; Monosaccharide Transport Proteins/genetics ; Repetitive Sequences, Nucleic Acid ; Replication Origin ; Saccharomyces cerevisiae Proteins/genetics
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies