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Tytuł :
Detection of multidrug-resistant Gram-negative bacteria from imported reptile and amphibian meats.
Autorzy :
Morrison BJ; Department of Veterinary Microbiology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Rubin JE; Department of Veterinary Microbiology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
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Źródło :
Journal of applied microbiology [J Appl Microbiol] 2020 Oct; Vol. 129 (4), pp. 1053-1061. Date of Electronic Publication: 2020 May 13.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Resistance, Multiple, Bacterial*/genetics
Internationality*
Anti-Bacterial Agents/*pharmacology
Gram-Negative Bacteria/*isolation & purification
Meat/*microbiology
Amphibians ; Animals ; Canada ; Drug Resistance, Bacterial/genetics ; Gram-Negative Bacteria/drug effects ; Gram-Negative Bacteria/genetics ; Reptiles
Czasopismo naukowe
Tytuł :
IRE1α-targeting downregulates ABC transporters and overcomes drug resistance of colon cancer cells.
Autorzy :
Gao Q; Shanghai Institute of Nutrition and Health, Shanghai Institutes of Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, 200031, China.
Li XX; Shanghai Institute of Nutrition and Health, Shanghai Institutes of Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, 200031, China.
Xu YM; Shanghai Institute of Nutrition and Health, Shanghai Institutes of Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, 200031, China.
Zhang JZ; Shanghai Institute of Nutrition and Health, Shanghai Institutes of Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, 200031, China.
Rong SD; Shanghai Institute of Nutrition and Health, Shanghai Institutes of Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, 200031, China.
Qin YQ; Shanghai Institute of Nutrition and Health, Shanghai Institutes of Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, 200031, China.
Fang J; Cancer Institute, The Affiliated Hospital of Qingdao University, Qingdao, 266061, China; Cancer Institute, Qingdao University, Qingdao, 266061, China. Electronic address: .
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Źródło :
Cancer letters [Cancer Lett] 2020 Apr 28; Vol. 476, pp. 67-74. Date of Electronic Publication: 2020 Feb 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Resistance, Neoplasm*
ATP Binding Cassette Transporter, Subfamily G, Member 2/*antagonists & inhibitors
Colonic Neoplasms/*drug therapy
Endoribonucleases/*antagonists & inhibitors
Fluorouracil/*pharmacology
Multidrug Resistance-Associated Proteins/*antagonists & inhibitors
Neoplasm Proteins/*antagonists & inhibitors
Protein-Serine-Threonine Kinases/*antagonists & inhibitors
ATP Binding Cassette Transporter, Subfamily B/antagonists & inhibitors ; ATP Binding Cassette Transporter, Subfamily B/genetics ; ATP Binding Cassette Transporter, Subfamily B/metabolism ; ATP Binding Cassette Transporter, Subfamily G, Member 2/genetics ; ATP Binding Cassette Transporter, Subfamily G, Member 2/metabolism ; Animals ; Antimetabolites, Antineoplastic/pharmacology ; Apoptosis ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Cell Proliferation ; Colonic Neoplasms/metabolism ; Colonic Neoplasms/pathology ; Drug Resistance, Multiple ; Endoribonucleases/genetics ; Endoribonucleases/metabolism ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Multidrug Resistance-Associated Proteins/genetics ; Multidrug Resistance-Associated Proteins/metabolism ; Neoplasm Proteins/genetics ; Neoplasm Proteins/metabolism ; Protein-Serine-Threonine Kinases/genetics ; Protein-Serine-Threonine Kinases/metabolism ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Prevalence and Multidrug Resistance Pattern of Salmonella Carrying Extended-Spectrum β-Lactamase in Frozen Chicken Meat in Bangladesh.
Autorzy :
Parvin MS; Population Medicine and AMR Laboratory, Department of Medicine, Farmgate, Dhaka-1215, Bangladesh.
Hasan MM; Population Medicine and AMR Laboratory, Department of Medicine, Farmgate, Dhaka-1215, Bangladesh.
Ali MY; Population Medicine and AMR Laboratory, Department of Medicine, Farmgate, Dhaka-1215, Bangladesh.; Department of Livestock Services, Farmgate, Dhaka-1215, Bangladesh.
Chowdhury EH; Department of Pathology, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh.
Rahman MT; Department of Microbiology and Hygiene, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh.
Islam MT; Population Medicine and AMR Laboratory, Department of Medicine, Farmgate, Dhaka-1215, Bangladesh.
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Źródło :
Journal of food protection [J Food Prot] 2020 Dec 01; Vol. 83 (12), pp. 2107-2121.
Typ publikacji :
Journal Article
MeSH Terms :
Chickens*
Drug Resistance, Bacterial*
Animals ; Anti-Bacterial Agents/pharmacology ; Bangladesh/epidemiology ; Drug Resistance, Multiple ; Humans ; Meat ; Prevalence ; Salmonella/genetics ; beta-Lactamases/genetics
Czasopismo naukowe
Tytuł :
Combined resistance and aerobic exercise intervention improves fitness, insulin resistance and quality of life in survivors of childhood haemopoietic stem cell transplantation with total body irradiation.
Autorzy :
Davis NL; Department of Paediatric Endocrinology and Diabetes, Level 6 UHBristol Education Centre, University Hospitals Bristol & Weston NHS Foundation Trust, Bristol, UK.
Tolfrey K; School of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, UK.
Jenney M; Department of Paediatric Oncology, Children's Hospital for Wales, Cardiff, UK.
Elson R; Department of Paediatric Oncology, Bristol Royal Hospital for Children, University Hospitals Bristol & Weston NHS Foundation Trust, Bristol, UK.
Stewart C; Stem cells, Ageing and Molecular Physiology Unit, Research Institute for Sport and Exercise Science, Liverpool John Moores University, Liverpool, Merseyside, UK.
Moss AD; Stem cells, Ageing and Molecular Physiology Unit, Research Institute for Sport and Exercise Science, Liverpool John Moores University, Liverpool, Merseyside, UK.
Cornish JM; Department of Paediatric Oncology, Bristol Royal Hospital for Children, Bristol, UK.
Stevens MCG; Bristol Medical School, Translational Health Sciences, University of Bristol, Bristol, UK.
Crowne EC; Department of Paediatric Endocrinology and Diabetes, Level 6 UHBristol Education Centre, University Hospitals Bristol & Weston NHS Foundation Trust, Bristol, UK.
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Źródło :
Pediatric blood & cancer [Pediatr Blood Cancer] 2020 Dec; Vol. 67 (12), pp. e28687. Date of Electronic Publication: 2020 Oct 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Exercise*
Insulin Resistance*
Quality of Life*
Cancer Survivors/*statistics & numerical data
Hematologic Neoplasms/*rehabilitation
Hematopoietic Stem Cell Transplantation/*methods
Whole-Body Irradiation/*methods
Adolescent ; Adult ; Body Composition ; Cardiorespiratory Fitness ; Child ; Combined Modality Therapy ; Female ; Follow-Up Studies ; Hematologic Neoplasms/pathology ; Hematologic Neoplasms/therapy ; Humans ; Longitudinal Studies ; Male ; Prognosis ; Resistance Training ; Young Adult
Czasopismo naukowe
Tytuł :
Selective concentrations for trimethoprim resistance in aquatic environments.
Autorzy :
Kraupner N; Centre for Antibiotic Resistance Research (CARe) at the University of Gothenburg, Gothenburg, Sweden; Department of Infectious Diseases, Institute of Biomedicine, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
Ebmeyer S; Centre for Antibiotic Resistance Research (CARe) at the University of Gothenburg, Gothenburg, Sweden; Department of Infectious Diseases, Institute of Biomedicine, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
Hutinel M; Centre for Antibiotic Resistance Research (CARe) at the University of Gothenburg, Gothenburg, Sweden; Department of Infectious Diseases, Institute of Biomedicine, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
Fick J; Department of Chemistry, Umeå University, Sweden.
Flach CF; Centre for Antibiotic Resistance Research (CARe) at the University of Gothenburg, Gothenburg, Sweden; Department of Infectious Diseases, Institute of Biomedicine, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
Larsson DGJ; Centre for Antibiotic Resistance Research (CARe) at the University of Gothenburg, Gothenburg, Sweden; Department of Infectious Diseases, Institute of Biomedicine, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden. Electronic address: .
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Źródło :
Environment international [Environ Int] 2020 Nov; Vol. 144, pp. 106083. Date of Electronic Publication: 2020 Sep 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Escherichia coli*/genetics
Trimethoprim Resistance*/genetics
Anti-Bacterial Agents/pharmacology ; Drug Resistance, Microbial ; Humans ; Trimethoprim/toxicity
Czasopismo naukowe
Tytuł :
An understated danger: Antimicrobial resistance in aquaculture and pet fish in Switzerland, a retrospective study from 2000 to 2017.
Autorzy :
Delalay G; Veterinary Public Health Institute, University of Bern, Bern, Switzerland.; Centre for Fish and Wildlife Health, Department of Infectious Diseases and Pathobiology, University of Bern, Bern, Switzerland.; Department of Animal Health, Federal Food Safety and Veterinary Office FSVO, Bern, Switzerland.
Berezowski JA; Veterinary Public Health Institute, University of Bern, Bern, Switzerland.
Diserens N; Koipraxis GmbH, Ulmiz, Switzerland.
Schmidt-Posthaus H; Centre for Fish and Wildlife Health, Department of Infectious Diseases and Pathobiology, University of Bern, Bern, Switzerland.
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Źródło :
Journal of fish diseases [J Fish Dis] 2020 Oct; Vol. 43 (10), pp. 1299-1315. Date of Electronic Publication: 2020 Aug 24.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Resistance, Bacterial*
Anti-Infective Agents/*pharmacology
Fishes/*microbiology
Animals ; Aquaculture ; Drug Resistance, Multiple, Bacterial ; Fish Diseases/microbiology ; Microbial Sensitivity Tests ; Pets/microbiology ; Retrospective Studies ; Switzerland
Czasopismo naukowe
Tytuł :
Molecular biological analysis of 5-FU-resistant gastric cancer organoids; KHDRBS3 contributes to the attainment of features of cancer stem cell.
Autorzy :
Ukai S; Department of Molecular Pathology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Honma R; Department of Molecular Pathology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Sakamoto N; Department of Molecular Pathology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Yamamoto Y; Division of Molecular and Cellular Medicine, National Cancer Center Research Institute, Tokyo, Japan.
Pham QT; Department of Molecular Pathology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Harada K; Department of Molecular Pathology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Takashima T; Department of Molecular Pathology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Taniyama D; Department of Molecular Pathology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Asai R; Department of Molecular Pathology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Fukada K; Department of Molecular Pathology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Naka K; Department of Stem Cell Biology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan.
Tanabe K; Department of Health Care for Adults, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Ohdan H; Department of Gastroenterological and Transplant Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Yasui W; Department of Molecular Pathology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan. .
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Źródło :
Oncogene [Oncogene] 2020 Dec; Vol. 39 (50), pp. 7265-7278. Date of Electronic Publication: 2020 Oct 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Resistance, Neoplasm*
Fluorouracil/*pharmacology
Neoplastic Stem Cells/*drug effects
Neoplastic Stem Cells/*pathology
Organoids/*drug effects
RNA-Binding Proteins/*metabolism
Stomach Neoplasms/*pathology
Aged ; Cell Line, Tumor ; Drug Resistance, Multiple ; Female ; Gene Knockout Techniques ; Humans ; Male ; Middle Aged ; Organoids/pathology ; Prognosis ; RNA-Binding Proteins/genetics ; Stomach Neoplasms/diagnosis ; Stomach Neoplasms/genetics ; Stomach Neoplasms/metabolism
Czasopismo naukowe
Tytuł :
Triangular Relationship between p53, Autophagy, and Chemotherapy Resistance.
Autorzy :
Xu J; School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Patel NH; Massey Cancer Center, Goodwin Research Laboratories, Virginia Commonwealth University, Richmond, VA 23298, USA.; Department of Pharmacology and Toxicology and Medicine, Virginia Commonwealth University, Richmond, VA 23298, USA.
Gewirtz DA; Massey Cancer Center, Goodwin Research Laboratories, Virginia Commonwealth University, Richmond, VA 23298, USA.; Department of Pharmacology and Toxicology and Medicine, Virginia Commonwealth University, Richmond, VA 23298, USA.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Nov 26; Vol. 21 (23). Date of Electronic Publication: 2020 Nov 26.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Autophagy*
Drug Resistance, Neoplasm*
Tumor Suppressor Protein p53/*metabolism
Animals ; Drug Resistance, Multiple ; Humans ; Models, Biological ; Neoplasms/drug therapy ; Neoplasms/pathology
Czasopismo naukowe
Tytuł :
Hyperinsulinaemia in cancer.
Autorzy :
Gallagher EJ; Division of Endocrinology, Diabetes and Bone Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA. .; The Tisch Cancer Institute at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, USA. .
LeRoith D; Division of Endocrinology, Diabetes and Bone Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; The Tisch Cancer Institute at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
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Źródło :
Nature reviews. Cancer [Nat Rev Cancer] 2020 Nov; Vol. 20 (11), pp. 629-644. Date of Electronic Publication: 2020 Sep 09.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Insulin Resistance*/physiology
Antigens, CD/*metabolism
Diabetes Mellitus, Type 2/*metabolism
Hyperinsulinism/*metabolism
Neoplasms/*metabolism
Obesity/*metabolism
Receptor, Insulin/*metabolism
Comorbidity ; Diabetes Mellitus, Type 2/blood ; Diabetes Mellitus, Type 2/epidemiology ; Drug Resistance, Neoplasm/physiology ; Humans ; Hyperinsulinism/blood ; Hyperinsulinism/epidemiology ; Insulin/blood ; Insulin/metabolism ; Neoplasms/blood ; Neoplasms/epidemiology ; Obesity/blood ; Obesity/epidemiology ; Signal Transduction
Czasopismo naukowe
Tytuł :
Antibiotic resistance and virulence of Escherichia coli strains isolated from animal rendering plant.
Autorzy :
Gregova G; University of Veterinary Medicine and Pharmacy in Kosice, Komenskeho 73, 041 81, Kosice, Slovakia. .
Kmet V; Institute of Animal Physiology, Centre of Biosciences, Slovak Academy of Sciences, Soltesovej 4, 040 01, Kosice, Slovakia.
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Źródło :
Scientific reports [Sci Rep] 2020 Oct 13; Vol. 10 (1), pp. 17108. Date of Electronic Publication: 2020 Oct 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Resistance, Bacterial*
Meat-Packing Industry*
Escherichia coli/*drug effects
Animals ; Anti-Bacterial Agents/pharmacology ; Escherichia coli/genetics ; Escherichia coli/isolation & purification ; Escherichia coli/pathogenicity ; Microbial Sensitivity Tests ; Polymerase Chain Reaction ; Virulence/genetics ; Virulence Factors/genetics ; beta-Lactam Resistance
Czasopismo naukowe
Tytuł :
MRP1-Collateral Sensitizers as a Novel Therapeutic Approach in Resistant Cancer Therapy: An In Vitro and In Vivo Study in Lung Resistant Tumor.
Autorzy :
Riganti C; Department of Oncology, University of Turin, Via Santena 5/bis, 10126 Turin, Italy.
Giampietro R; Department of Pharmacy-Drug Sciences, University of Bari 'A. Moro', Via Orabona 4, 70125 Bari, Italy.
Kopecka J; Department of Oncology, University of Turin, Via Santena 5/bis, 10126 Turin, Italy.
Costamagna C; Department of Oncology, University of Turin, Via Santena 5/bis, 10126 Turin, Italy.
Abatematteo FS; Department of Pharmacy-Drug Sciences, University of Bari 'A. Moro', Via Orabona 4, 70125 Bari, Italy.
Contino M; Department of Pharmacy-Drug Sciences, University of Bari 'A. Moro', Via Orabona 4, 70125 Bari, Italy.
Abate C; Department of Pharmacy-Drug Sciences, University of Bari 'A. Moro', Via Orabona 4, 70125 Bari, Italy.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 May 08; Vol. 21 (9). Date of Electronic Publication: 2020 May 08.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Collateral Sensitivity*
Drug Resistance, Neoplasm*
Antineoplastic Agents/*pharmacology
Carcinoma, Non-Small-Cell Lung/*drug therapy
Cell Proliferation/*drug effects
Lung Neoplasms/*drug therapy
Multidrug Resistance-Associated Proteins/*metabolism
Animals ; Carcinoma, Non-Small-Cell Lung/enzymology ; Cell Line, Tumor ; Cell Survival/drug effects ; Drug Resistance, Multiple ; Female ; Glutathione/metabolism ; Humans ; Ligands ; Lung Neoplasms/enzymology ; Mice ; Mice, Inbred BALB C ; Reactive Oxygen Species/metabolism ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
A fast and robust iterative genome-editing method based on a Rock-Paper-Scissors strategy.
Autorzy :
Wang J; CAS Key Lab of Biobased Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, 266101 Qingdao, China.
Sui X; CAS Key Lab of Biobased Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, 266101 Qingdao, China.; University of Chinese Academy of Sciences, 100049 Beijing, China.
Ding Y; Institute of Oceanology, Chinese Academy of Sciences, 266071 Qingdao, China.
Fu Y; CAS Key Lab of Biobased Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, 266101 Qingdao, China.
Feng X; CAS Key Lab of Biobased Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, 266101 Qingdao, China.
Liu M; CAS Key Lab of Biobased Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, 266101 Qingdao, China.; State Key Laboratory of Microbial Technology, Shandong University, 266237 Qingdao, China.
Zhang Y; State Key Laboratory of Microbial Technology, Shandong University, 266237 Qingdao, China.
Xian M; CAS Key Lab of Biobased Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, 266101 Qingdao, China.
Zhao G; CAS Key Lab of Biobased Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, 266101 Qingdao, China.; State Key Laboratory of Microbial Technology, Shandong University, 266237 Qingdao, China.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2021 Jan 25; Vol. 49 (2), pp. e12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Resistance, Microbial/*genetics
Gene Editing/*methods
Plasmids/*genetics
RNA, Guide/*genetics
CRISPR-Cas Systems ; Chloramphenicol/pharmacology ; Clone Cells ; Escherichia coli/drug effects ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Gene Expression Regulation, Bacterial ; Gene Knockout Techniques ; Genes, Bacterial ; Kanamycin/pharmacology ; Kanamycin Resistance/genetics ; Klebsiella pneumoniae/drug effects ; Klebsiella pneumoniae/genetics ; Klebsiella pneumoniae/metabolism ; Lactates/metabolism ; Mutation ; Nucleotide Motifs ; Promoter Regions, Genetic/genetics ; Pyruvic Acid/metabolism ; Selection, Genetic ; Tetracycline/pharmacology ; Tetracycline Resistance/genetics ; Time Factors ; Transformation, Bacterial
Czasopismo naukowe
Tytuł :
Ursolic acid reduces Adriamycin resistance of human ovarian cancer cells through promoting the HuR translocation from cytoplasm to nucleus.
Autorzy :
Li W; Department of Gynaecology, The Forth Hospital Affiliated to Jiangsu University, Zhenjiang, China.
Luo L; Department of Obstetrics and Gynecology, Jiangsu Taizhou People's Hospital, Taizhou, China.
Shi W; Department of Gynaecology, the Fourth People's Hospital Affiliated to Jiangsu University, 20 Zhengdong Road, Zhenjiang, 212001, China.
Yin Y; Department of Obstetrics and Gynecology, Dantu District People's Hospital of Zhenjiang, Zhenjiang, China.
Gao S; Department of Obstetrics and Gynecology, Second Provincial People's Hospital of Gansu, the Affiliated Hospital of Northwest Minzu University, Lanzhou, China.
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Źródło :
Environmental toxicology [Environ Toxicol] 2021 Feb; Vol. 36 (2), pp. 267-275. Date of Electronic Publication: 2020 Oct 03.
Typ publikacji :
Journal Article
MeSH Terms :
Antibiotics, Antineoplastic/*pharmacology
Cell Nucleus/*metabolism
Cytoplasm/*metabolism
Doxorubicin/*pharmacology
Drug Resistance, Neoplasm/*drug effects
ELAV-Like Protein 1/*metabolism
Ovarian Neoplasms/*pathology
Triterpenes/*pharmacology
Cell Line, Tumor ; Drug Resistance, Multiple/drug effects ; Female ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Ovarian Neoplasms/genetics ; Protein Transport ; RNA, Messenger/metabolism
Czasopismo naukowe
Tytuł :
Critical discovery and synthesis of novel antibacterial and resistance-modifying agents inspired by plant phytochemical defense mechanisms.
Autorzy :
Soliman SSM; Research Institute for Medical and Health sciences, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates; College of Pharmacy, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates; Faculty of Pharmacy, Zagazig University, Zagazig, 44519, Egypt. Electronic address: .
Saeed BQ; Research Institute for Medical and Health sciences, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates; Department of Clinical Sciences, College of Medicine, University of Sharjah, P.O. Box 27272, United Arab Emirates.
Elseginy SA; Green Chemistry Department, Chemical Industries Research Division, National Research Center, P.O. Box 12622, Egypt; Molecular Modelling Lab., Biochemistry School, Bristol University, Bristol, UK.
Al-Marzooq F; Research Institute for Medical and Health sciences, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates; Department of medical microbiology and immunology, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates.
Ahmady IM; Department of Applied Biology, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates.
El-Keblawy AA; Department of Applied Biology, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates; Research Institutes of Science and Engineering, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates.
Hamdy R; Research Institute for Medical and Health sciences, University of Sharjah, P.O. Box 27272, Sharjah, United Arab Emirates; Faculty of Pharmacy, Zagazig University, Zagazig, 44519, Egypt.
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Źródło :
Chemico-biological interactions [Chem Biol Interact] 2021 Jan 05; Vol. 333, pp. 109318. Date of Electronic Publication: 2020 Nov 10.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Design*
Anti-Bacterial Agents/*chemical synthesis
Anti-Bacterial Agents/*pharmacology
Caryophyllales/*chemistry
Drug Resistance, Bacterial/*drug effects
Oils, Volatile/*chemistry
Phytochemicals/*chemistry
Anti-Bacterial Agents/chemistry ; Biomimetic Materials/chemical synthesis ; Biomimetic Materials/chemistry ; Biomimetic Materials/pharmacology ; Cell Line ; Chemistry Techniques, Synthetic ; Drug Resistance, Multiple/drug effects ; Humans
Czasopismo naukowe
Tytuł :
Poncirin downregulates ATP-binding cassette transporters to enhance cisplatin sensitivity in cisplatin-resistant osteosarcoma cells.
Autorzy :
Zhao L; Department of Orthopedics, Shanxian Central Hospital, Heze, China.
Zhang W; Department of Oncology, Shanxian Central Hospital, Heze, China.
Zhang F; Department of Orthopedics, Shanxian Central Hospital, Heze, China.
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Źródło :
Phytotherapy research : PTR [Phytother Res] 2021 Jan; Vol. 35 (1), pp. 278-288. Date of Electronic Publication: 2020 Aug 11.
Typ publikacji :
Journal Article
MeSH Terms :
ATP-Binding Cassette Transporters/*metabolism
Antineoplastic Agents/*pharmacology
Cisplatin/*pharmacology
Drug Resistance, Neoplasm/*drug effects
Flavonoids/*pharmacology
Osteosarcoma/*metabolism
ATP Binding Cassette Transporter, Subfamily B/metabolism ; ATP Binding Cassette Transporter, Subfamily G, Member 2 ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Humans ; Multidrug Resistance-Associated Proteins/metabolism ; Neoplasm Proteins/metabolism ; Osteosarcoma/drug therapy ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism
Czasopismo naukowe
Tytuł :
State of Artemisinin and Partner Drug Susceptibility in Plasmodium falciparum Clinical Isolates from Colombia.
Autorzy :
Montenegro LM; 1Grupo Malaria, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia.
de Las Salas B; 1Grupo Malaria, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia.
Neal AT; 2Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland.
Tobon-Castaño A; 1Grupo Malaria, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia.
Fairhurst RM; 2Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland.
Lopera-Mesa TM; 1Grupo Malaria, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia.
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Źródło :
The American journal of tropical medicine and hygiene [Am J Trop Med Hyg] 2021 Jan; Vol. 104 (1), pp. 263-270.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antimalarials/*pharmacology
Drug Resistance/*genetics
Malaria, Falciparum/*parasitology
Plasmodium falciparum/*drug effects
Adolescent ; Adult ; Antimalarials/therapeutic use ; Colombia/epidemiology ; Female ; Humans ; Malaria, Falciparum/drug therapy ; Malaria, Falciparum/epidemiology ; Male ; Multidrug Resistance-Associated Proteins/genetics ; Multidrug Resistance-Associated Proteins/metabolism ; Polymerase Chain Reaction/methods ; Young Adult
Czasopismo naukowe
Tytuł :
Exploiting evolutionary trade-offs for posttreatment management of drug-resistant populations.
Autorzy :
Melnikov SV; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520; .
Stevens DL; Department of Chemistry, Yale University, New Haven, CT 06520.
Fu X; Guangdong Provincial Key Laboratory of Genome Read and Write, 518120 Shenzhen, China.; BGI-Shenzhen, 518083 Shenzhen, China.; China National Genebank, BGI-Shenzhen, 518120 Shenzhen, China.
Kwok HS; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520.
Zhang JT; BGI-Shenzhen, 518083 Shenzhen, China.; China National Genebank, BGI-Shenzhen, 518120 Shenzhen, China.
Shen Y; Guangdong Provincial Key Laboratory of Genome Read and Write, 518120 Shenzhen, China.; BGI-Shenzhen, 518083 Shenzhen, China.; China National Genebank, BGI-Shenzhen, 518120 Shenzhen, China.
Sabina J; Thermo Fisher Scientific, Guilford, CT 06437.
Lee K; Erbi Biosystems, Woburn, MA 01801.
Lee H; Erbi Biosystems, Woburn, MA 01801.
Söll D; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520; .; Department of Chemistry, Yale University, New Haven, CT 06520.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Jul 28; Vol. 117 (30), pp. 17924-17931. Date of Electronic Publication: 2020 Jul 13.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Biological Evolution*
Drug Resistance*
Anti-Bacterial Agents/pharmacology ; Drug Resistance, Bacterial ; Escherichia coli/drug effects ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Escherichia coli Proteins/chemistry ; Escherichia coli Proteins/genetics ; Genetic Variation ; Models, Molecular ; Protein Conformation ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Plasmid stability of potential probiotic Lactobacillus plantarum strains in artificial gastric juice, at elevated temperature, and in the presence of novobiocin and acriflavine.
Autorzy :
Sağlam H; Department of Molecular Biology and Genetics, Faculty of Arts and Sciences, Kilis 7 Aralık University, Kilis, Turkey. .
Karahan AG; Department of Food Engineering, Faculty of Engineering, Süleyman Demirel University, Isparta, Turkey.
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Źródło :
Archives of microbiology [Arch Microbiol] 2021 Jan; Vol. 203 (1), pp. 183-191. Date of Electronic Publication: 2020 Aug 16.
Typ publikacji :
Journal Article
MeSH Terms :
Acriflavine/*pharmacology
Drug Resistance, Bacterial/*genetics
Gastric Juice/*microbiology
Lactobacillus plantarum/*drug effects
Novobiocin/*pharmacology
Anti-Bacterial Agents/pharmacology ; Fermentation ; Gastric Juice/drug effects ; Hot Temperature ; Lactobacillus plantarum/genetics ; Plasmids/genetics ; Probiotics ; Tetracycline Resistance/genetics
Czasopismo naukowe
Tytuł :
Mathematical basis for the assessment of antibiotic resistance and administrative counter-strategies.
Autorzy :
Diebner HH; Carl Gustav Carus Faculty of Medicine, Institute for Medical Informatics and Biometry, Technische Universität Dresden, Dresden, Germany.
Kather A; University Hospital Carl Gustav Carus Dresden at the TU Dresden, Division of Infectious Diseases, Dresden, Germany.
Roeder I; Carl Gustav Carus Faculty of Medicine, Institute for Medical Informatics and Biometry, Technische Universität Dresden, Dresden, Germany.
de With K; University Hospital Carl Gustav Carus Dresden at the TU Dresden, Division of Infectious Diseases, Dresden, Germany.
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Źródło :
PloS one [PLoS One] 2020 Sep 03; Vol. 15 (9), pp. e0238692. Date of Electronic Publication: 2020 Sep 03 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Resistance, Microbial*
Models, Biological*
Anti-Bacterial Agents/pharmacology ; Bacteria/drug effects ; Drug Resistance, Bacterial ; Time Factors
Czasopismo naukowe
Tytuł :
Combined Aerobic and Resistance Exercises Evokes Longer Reductions on Ambulatory Blood Pressure in Resistant Hypertension: A Randomized Crossover Trial.
Autorzy :
Pires NF; Laboratory of Cardiovascular Pharmacology, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.
Coelho-Júnior HJ; Laboratory of Cardiovascular Investigation and Exercise, School of Physical Education (FEF), University of Campinas (UNICAMP), Campinas, Brazil.; Departament of Internal Medicine and Geriatrics, Catholic University of Sacred Heart, Rome, Italy.
Gambassi BB; Laboratory of Cardiovascular Investigation and Exercise, School of Physical Education (FEF), University of Campinas (UNICAMP), Campinas, Brazil.; Department of Physical Education, Ceuma University, São Luís, Brazil.
de Faria APC; Laboratory of Cardiovascular Pharmacology, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.
Ritter AMV; Laboratory of Cardiovascular Pharmacology, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.
de Andrade Barboza C; Laboratory of Cardiovascular Pharmacology, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.; Laboratory of Cardiovascular Investigation and Exercise, School of Physical Education (FEF), University of Campinas (UNICAMP), Campinas, Brazil.
Ferreira-Melo SE; Laboratory of Cardiovascular Pharmacology, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.
Rodrigues B; Laboratory of Cardiovascular Pharmacology, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.; Laboratory of Cardiovascular Investigation and Exercise, School of Physical Education (FEF), University of Campinas (UNICAMP), Campinas, Brazil.
Júnior HM; Laboratory of Cardiovascular Pharmacology, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.
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Źródło :
Cardiovascular therapeutics [Cardiovasc Ther] 2020 Jul 20; Vol. 2020, pp. 8157858. Date of Electronic Publication: 2020 Jul 20 (Print Publication: 2020).
Typ publikacji :
Comparative Study; Journal Article; Randomized Controlled Trial
MeSH Terms :
Blood Pressure*/drug effects
Resistance Training*
Hypertension/*therapy
Adult ; Aged ; Antihypertensive Agents/therapeutic use ; Blood Pressure Monitoring, Ambulatory ; Brazil ; Cross-Over Studies ; Drug Resistance ; Female ; Humans ; Hypertension/diagnosis ; Hypertension/physiopathology ; Male ; Middle Aged ; Time Factors ; Treatment Outcome
Czasopismo naukowe

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