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Wyszukujesz frazę ""RACEMIZATION"" wg kryterium: Wszystkie pola


Tytuł :
Racemization of the Succinimide Intermediate Formed in Proteins and Peptides: A Computational Study of the Mechanism Catalyzed by Dihydrogen Phosphate Ion.
Autorzy :
Takahashi O; Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai 981-8558, Japan. .
Kirikoshi R; Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai 981-8558, Japan. .
Manabe N; Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai 981-8558, Japan. .
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2016 Oct 10; Vol. 17 (10). Date of Electronic Publication: 2016 Oct 10.
Typ publikacji :
Journal Article
MeSH Terms :
Models, Chemical*
Peptides/*chemistry
Phosphates/*chemistry
Proteins/*chemistry
Succinimides/*chemistry
Catalysis ; Ions/chemistry ; Stereoisomerism ; Thermodynamics
Czasopismo naukowe
Tytuł :
Evaluation of acid-labile S-protecting groups to prevent Cys racemization in Fmoc solid-phase peptide synthesis.
Autorzy :
Hibino H; SAITO Research Center, Peptide Institute, Inc., Ibaraki, Osaka, 567-0085, Japan.
Miki Y
Nishiuchi Y
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Źródło :
Journal of peptide science : an official publication of the European Peptide Society [J Pept Sci] 2014 Jan; Vol. 20 (1), pp. 30-5. Date of Electronic Publication: 2013 Nov 28.
Typ publikacji :
Evaluation Study; Journal Article
MeSH Terms :
Solid-Phase Synthesis Techniques*
Peptides/*chemical synthesis
Amino Acid Sequence ; Amino Acids/chemistry ; Dimethylformamide/chemistry ; Fluorenes/chemistry ; Microwaves ; Organophosphorus Compounds/chemistry ; Piperidines/chemistry ; Solvents/chemistry ; Stereoisomerism ; Triazoles/chemistry
Czasopismo naukowe
Tytuł :
Oxyma-B, an excellent racemization suppressor for peptide synthesis.
Autorzy :
Jad YE; Catalysis and Peptide Research Unit, School of Health Sciences, University of Kwazulu-Natal, Durban 4001, South Africa. .
Khattab SN
de la Torre BG
Govender T
Kruger HG
El-Faham A
Albericio F
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Źródło :
Organic & biomolecular chemistry [Org Biomol Chem] 2014 Nov 14; Vol. 12 (42), pp. 8379-85.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Barbiturates/*chemistry
Oximes/*chemistry
Peptides/*chemical synthesis
Solid-Phase Synthesis Techniques/*methods
Amino Acid Sequence ; Peptides/chemistry
Czasopismo naukowe
Tytuł :
Ethyl 2-cyano-2-(2-nitrobenzenesulfonyloxyimino)acetate (o-NosylOXY): a recyclable coupling reagent for racemization-free synthesis of peptide, amide, hydroxamate, and ester.
Autorzy :
Dev D; Department of Chemistry, Indian Institute of Technology Guwahati , Guwahati, Assam 781039, India.
Palakurthy NB
Thalluri K
Chandra J
Mandal B
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Źródło :
The Journal of organic chemistry [J Org Chem] 2014 Jun 20; Vol. 79 (12), pp. 5420-31. Date of Electronic Publication: 2014 Jun 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Amides/*chemical synthesis
Amino Acids/*chemical synthesis
Amyloid/*chemistry
Amyloid beta-Peptides/*chemistry
Nitro Compounds/*chemistry
Peptides/*chemical synthesis
Amides/chemistry ; Amino Acids/chemistry ; Esters ; Peptides/chemistry ; Solid-Phase Synthesis Techniques ; Stereoisomerism
Czasopismo naukowe
Tytuł :
Aqueous microwave-assisted solid-phase peptide synthesis using fmoc strategy. II. Racemization studies and water based synthesis of cysteine-containing peptides.
Autorzy :
Hojo K; Faculty of Pharmaceutical Sciences & Cooperative Research Center of Life Sciences, Kobe Gakuin University, 1-1-3 Minatojima, Chuo-ku, Kobe 650-8586, Japan. />Shinozaki N
Hara A
Onishi M
Fukumori Y
Ichikawa H
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Źródło :
Protein and peptide letters [Protein Pept Lett] 2013 Oct; Vol. 20 (10), pp. 1122-8.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Amino Acids/*chemistry
Cysteine/*chemistry
Fluorenes/*chemistry
Nanoparticles/*chemistry
Oxytocin/*analogs & derivatives
Peptides/*chemical synthesis
Solid-Phase Synthesis Techniques/*methods
Amino Acid Sequence ; Amino Acids/chemical synthesis ; Cysteine/chemical synthesis ; Fluorenes/chemical synthesis ; Microwaves ; Peptides/chemistry ; Water/chemistry
Czasopismo naukowe
Tytuł :
Cysteine racemization during the Fmoc solid phase peptide synthesis of the Nav1.7-selective peptide--protoxin II.
Autorzy :
Park JH; Discovery Research, Purdue Pharma LP, 6 Cedar Brook Drive, Cranbury, NJ 08512, USA. />Carlin KP
Wu G
Ilyin VI
Kyle DJ
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Źródło :
Journal of peptide science : an official publication of the European Peptide Society [J Pept Sci] 2012 Jul; Vol. 18 (7), pp. 442-8. Date of Electronic Publication: 2012 May 17.
Typ publikacji :
Journal Article
MeSH Terms :
Solid-Phase Synthesis Techniques*
Cysteine/*chemistry
NAV1.7 Voltage-Gated Sodium Channel/*metabolism
Peptides/*chemical synthesis
Peptides/*metabolism
Sodium Channel Blockers/*chemical synthesis
Sodium Channel Blockers/*metabolism
Spider Venoms/*chemical synthesis
Spider Venoms/*metabolism
Cell Line ; Humans ; Morpholines/chemistry ; Oxidation-Reduction ; Peptides/chemistry ; Sodium Channel Blockers/chemistry ; Spider Venoms/chemistry ; Stereoisomerism ; Substrate Specificity
Czasopismo naukowe
Tytuł :
Native chemical ligation in dimethylformamide can be performed chemoselectively without racemization.
Autorzy :
Dittmann M; Max Planck Institute of Molecular Physiology, Otto Hahn Str. 11, 44227, Dortmund, Germany.
Sadek M
Seidel R
Engelhard M
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Źródło :
Journal of peptide science : an official publication of the European Peptide Society [J Pept Sci] 2012 May; Vol. 18 (5), pp. 312-6. Date of Electronic Publication: 2012 Mar 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Dimethylformamide/*chemistry
Peptides/*chemical synthesis
Peptides/*chemistry
Solvents/*chemistry
Hydrophobic and Hydrophilic Interactions ; Stereoisomerism
Czasopismo naukowe
Tytuł :
4-Methoxybenzyloxymethyl group, a racemization-resistant protecting group for cysteine in Fmoc solid phase peptide synthesis.
Autorzy :
Hibino H; SAITO Research Center, Peptide Institute, Inc., Ibaraki, Osaka 567-0085, Japan.
Nishiuchi Y
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Źródło :
Organic letters [Org Lett] 2012 Apr 06; Vol. 14 (7), pp. 1926-9. Date of Electronic Publication: 2012 Mar 27.
Typ publikacji :
Journal Article
MeSH Terms :
Cysteine/*chemistry
Fluorenes/*chemistry
Peptides/*chemical synthesis
Molecular Structure ; Peptides/chemistry ; Stereoisomerism
Czasopismo naukowe
Tytuł :
Identification of isomerization and racemization of aspartate in the Asp-Asp motifs of a therapeutic protein.
Autorzy :
Zhang J; Protein Analytical Chemistry, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080, USA. />Yip H
Katta V
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Źródło :
Analytical biochemistry [Anal Biochem] 2011 Mar 15; Vol. 410 (2), pp. 234-43. Date of Electronic Publication: 2010 Dec 02.
Typ publikacji :
Journal Article
MeSH Terms :
Chromatography, High Pressure Liquid/*methods
Dipeptides/*chemistry
Peptides/*chemistry
Tandem Mass Spectrometry/*methods
Amino Acid Motifs/physiology ; Amino Acid Sequence ; Complementarity Determining Regions/chemistry ; Immunoglobulin Fab Fragments/chemistry ; Isoelectric Focusing/methods ; Isomerism ; Molecular Sequence Data ; Peptide Mapping/methods ; Proteins/therapeutic use ; Succinimides/chemistry ; Temperature
Czasopismo naukowe
Tytuł :
Fragment condensation of C-terminal pseudoproline peptides without racemization on the solid phase.
Autorzy :
Heinlein C; Bioorganische Chemie, Gebäude NW1, Universität Bayreuth, 95440 Bayreuth, Germany.
Varón Silva D
Tröster A
Schmidt J
Gross A
Unverzagt C
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Źródło :
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2011 Jul 04; Vol. 50 (28), pp. 6406-10. Date of Electronic Publication: 2011 May 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Peptides/*chemistry
Proline/*analogs & derivatives
Thiazoles/*chemistry
Amino Acid Sequence ; Microwaves ; Molecular Sequence Data ; Peptides/chemical synthesis ; Proline/chemistry ; Ribonucleases/chemical synthesis ; Ribonucleases/chemistry ; Stereoisomerism
Czasopismo naukowe
Tytuł :
Peptide-Chain Elongation Using Unprotected Amino Acids in a Micro-Flow Reactor.
Autorzy :
Fuse S; Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, 226-8503, Japan.
Masuda K; Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, 226-8503, Japan.; School of Life Science and Technology, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, 226-8503, Japan.
Otake Y; Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, 226-8503, Japan.; School of Life Science and Technology, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, 226-8503, Japan.
Nakamura H; Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, 226-8503, Japan.
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Źródło :
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2019 Nov 27; Vol. 25 (66), pp. 15091-15097. Date of Electronic Publication: 2019 Oct 24.
Typ publikacji :
Journal Article
MeSH Terms :
Amino Acids/*chemistry
Peptides/*chemical synthesis
Carbon Dioxide/chemistry ; Chemistry Techniques, Synthetic ; Peptides/chemistry ; Stereoisomerism
Czasopismo naukowe
Tytuł :
Amino acid chlorides: a journey from instability and racemization toward broader utility in organic synthesis including peptides and their mimetics
Autorzy :
Prabhu, Girish
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Źródło :
In Tetrahedron 13 May 2015 71(19):2785-2832
Czasopismo naukowe

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