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Wyszukujesz frazę ""RANK Ligand"" wg kryterium: Temat


Tytuł :
RANKL Mediates Muscle Atrophy and Dysfunction in a Cigarette Smoke-induced Model of Chronic Obstructive Pulmonary Disease.
Autorzy :
Xiong J; Department of Respiratory and Critical Care Medicine, Peking University Third Hospital, Beijing, China; and.
Le Y; Department of Respiratory and Critical Care Medicine, Peking University Third Hospital, Beijing, China; and.
Rao Y; Department of Respiratory and Critical Care Medicine, Peking University Third Hospital, Beijing, China; and.
Zhou L; Department of Respiratory and Critical Care Medicine, Peking University Third Hospital, Beijing, China; and.
Hu Y; Department of Respiratory Medicine, and Medical Research Center, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Guo S; Department of Respiratory Medicine, and Medical Research Center, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Sun Y; Department of Respiratory and Critical Care Medicine, Peking University Third Hospital, Beijing, China; and.
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Źródło :
American journal of respiratory cell and molecular biology [Am J Respir Cell Mol Biol] 2021 May; Vol. 64 (5), pp. 617-628.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Muscular Atrophy/*genetics
NF-kappa B/*genetics
Pulmonary Disease, Chronic Obstructive/*genetics
RANK Ligand/*genetics
Receptor Activator of Nuclear Factor-kappa B/*genetics
Animals ; Antibodies, Neutralizing/pharmacology ; Cell Line ; Cigarette Smoking/adverse effects ; Complex Mixtures/antagonists & inhibitors ; Complex Mixtures/pharmacology ; Disease Models, Animal ; Female ; Gene Expression Regulation ; Hand Strength/physiology ; Insulin-Like Growth Factor I/genetics ; Insulin-Like Growth Factor I/metabolism ; Mice ; Mice, Inbred C57BL ; Muscle Fibers, Skeletal/drug effects ; Muscle Fibers, Skeletal/metabolism ; Muscle Fibers, Skeletal/pathology ; Muscle Proteins/genetics ; Muscle Proteins/metabolism ; Muscle Strength/drug effects ; Muscle Strength/genetics ; Muscle, Skeletal/drug effects ; Muscle, Skeletal/metabolism ; Muscle, Skeletal/pathology ; Muscular Atrophy/metabolism ; Muscular Atrophy/pathology ; Muscular Atrophy/prevention & control ; Myogenin/genetics ; Myogenin/metabolism ; Myostatin/genetics ; Myostatin/metabolism ; NF-kappa B/metabolism ; Pulmonary Disease, Chronic Obstructive/chemically induced ; Pulmonary Disease, Chronic Obstructive/metabolism ; Pulmonary Disease, Chronic Obstructive/prevention & control ; RANK Ligand/antagonists & inhibitors ; RANK Ligand/metabolism ; Receptor Activator of Nuclear Factor-kappa B/metabolism ; SKP Cullin F-Box Protein Ligases/genetics ; SKP Cullin F-Box Protein Ligases/metabolism ; Signal Transduction ; Tripartite Motif Proteins/genetics ; Tripartite Motif Proteins/metabolism ; Ubiquitin-Protein Ligases/genetics ; Ubiquitin-Protein Ligases/metabolism
Czasopismo naukowe
Tytuł :
RANKL regulates male reproductive function.
Autorzy :
Blomberg Jensen M; Group of Skeletal, Mineral and Gonadal Endocrinology, Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark. .; Division of Bone and Mineral Research, HSDM/HMS, Harvard University, Boston, MA, USA. .
Andreassen CH; Group of Skeletal, Mineral and Gonadal Endocrinology, Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Jørgensen A; Department of Growth and Reproduction and International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Nielsen JE; Department of Growth and Reproduction and International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Juel Mortensen L; Group of Skeletal, Mineral and Gonadal Endocrinology, Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.; Division of Bone and Mineral Research, HSDM/HMS, Harvard University, Boston, MA, USA.
Boisen IM; Group of Skeletal, Mineral and Gonadal Endocrinology, Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.; Division of Bone and Mineral Research, HSDM/HMS, Harvard University, Boston, MA, USA.
Schwarz P; Department of Endocrinology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Toppari J; Institute of Biomedicine, Research Centre for Integrated Physiology and Pharmacology, and Centre for Population Health Research, University of Turku, and Department of Pediatrics, Turku University Hospital, Turku, Finland.
Baron R; Division of Bone and Mineral Research, HSDM/HMS, Harvard University, Boston, MA, USA.
Lanske B; Division of Bone and Mineral Research, HSDM/HMS, Harvard University, Boston, MA, USA.
Juul A; Department of Growth and Reproduction and International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
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Źródło :
Nature communications [Nat Commun] 2021 Apr 23; Vol. 12 (1), pp. 2450. Date of Electronic Publication: 2021 Apr 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Fertility/*physiology
RANK Ligand/*metabolism
Semen Analysis/*methods
Sertoli Cells/*metabolism
Spermatozoa/*metabolism
Animals ; Anti-Mullerian Hormone/blood ; Anti-Mullerian Hormone/metabolism ; Denosumab/pharmacology ; Fertility/drug effects ; Humans ; Inhibins/antagonists & inhibitors ; Inhibins/blood ; Inhibins/metabolism ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Mice, Transgenic ; Osteoprotegerin/pharmacology ; RANK Ligand/antagonists & inhibitors ; RANK Ligand/genetics ; Semen/drug effects ; Semen/metabolism ; Sertoli Cells/drug effects ; Sperm Count ; Spermatozoa/cytology ; Spermatozoa/drug effects
Czasopismo naukowe
Tytuł :
The receptor activator of nuclear factor κΒ ligand receptor leucine-rich repeat-containing G-protein-coupled receptor 4 contributes to parathyroid hormone-induced vascular calcification.
Autorzy :
Carrillo-López N; Bone and Mineral Research Unit, Hospital Universitario Central de Asturias, Instituto de Investigación Sanitaria del Principado de Asturias, REDinREN-ISCIII, Oviedo, Spain.
Martínez-Arias L; Bone and Mineral Research Unit, Hospital Universitario Central de Asturias, Instituto de Investigación Sanitaria del Principado de Asturias, REDinREN-ISCIII, Oviedo, Spain.
Alonso-Montes C; Bone and Mineral Research Unit, Hospital Universitario Central de Asturias, Instituto de Investigación Sanitaria del Principado de Asturias, REDinREN-ISCIII, Oviedo, Spain.
Martín-Carro B; Bone and Mineral Research Unit, Hospital Universitario Central de Asturias, Instituto de Investigación Sanitaria del Principado de Asturias, REDinREN-ISCIII, Oviedo, Spain.
Martín-Vírgala J; Bone and Mineral Research Unit, Hospital Universitario Central de Asturias, Instituto de Investigación Sanitaria del Principado de Asturias, REDinREN-ISCIII, Oviedo, Spain.
Ruiz-Ortega M; Vascular and Renal Laboratory Fundación Jimenez Díaz, Universidad Autónoma Madrid, REDinREN-ISCIII, Madrid, Spain.
Fernández-Martín JL; Bone and Mineral Research Unit, Hospital Universitario Central de Asturias, Instituto de Investigación Sanitaria del Principado de Asturias, REDinREN-ISCIII, Oviedo, Spain.
Dusso AS; Bone and Mineral Research Unit, Hospital Universitario Central de Asturias, Instituto de Investigación Sanitaria del Principado de Asturias, REDinREN-ISCIII, Oviedo, Spain.
Rodriguez-García M; Bone and Mineral Research Unit, Hospital Universitario Central de Asturias, Instituto de Investigación Sanitaria del Principado de Asturias, REDinREN-ISCIII, Oviedo, Spain.; Departamento de Medicina, Universidad de Oviedo, Oviedo, Spain.
Naves-Díaz M; Bone and Mineral Research Unit, Hospital Universitario Central de Asturias, Instituto de Investigación Sanitaria del Principado de Asturias, REDinREN-ISCIII, Oviedo, Spain.
Cannata-Andía JB; Bone and Mineral Research Unit, Hospital Universitario Central de Asturias, Instituto de Investigación Sanitaria del Principado de Asturias, REDinREN-ISCIII, Oviedo, Spain.; Departamento de Medicina, Universidad de Oviedo, Oviedo, Spain.
Panizo S; Bone and Mineral Research Unit, Hospital Universitario Central de Asturias, Instituto de Investigación Sanitaria del Principado de Asturias, REDinREN-ISCIII, Oviedo, Spain.
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Źródło :
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association [Nephrol Dial Transplant] 2021 Mar 29; Vol. 36 (4), pp. 618-631.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Myocytes, Smooth Muscle/*metabolism
Osteoprotegerin/*metabolism
Parathyroid Hormone/*pharmacology
RANK Ligand/*metabolism
Receptor Activator of Nuclear Factor-kappa B/*metabolism
Receptors, G-Protein-Coupled/*metabolism
Vascular Calcification/*metabolism
Animals ; Calcium-Regulating Hormones and Agents/pharmacology ; Gene Expression Regulation/drug effects ; Ligands ; Male ; NF-kappa B/metabolism ; Osteoprotegerin/genetics ; RANK Ligand/genetics ; Rats ; Rats, Wistar ; Receptor Activator of Nuclear Factor-kappa B/genetics ; Receptors, G-Protein-Coupled/genetics
Czasopismo naukowe
Tytuł :
Uterine leiomyosarcomas with osteoclast-like giant cells associated with high expression of RUNX2 and RANKL.
Autorzy :
Terasaki M; Department of Analytic Human Pathology, Nippon Medical School, 1-25-16, Nezu, Bunkyo-ku, Tokyo, 113-0031, Japan. .
Terasaki Y; Department of Analytic Human Pathology, Nippon Medical School, 1-25-16, Nezu, Bunkyo-ku, Tokyo, 113-0031, Japan.; Division of Pathology, Nippon Medical School Hospital, 1-1-5, Sendagi, Bunkyo-ku, Tokyo, 113-8602, Japan.
Wakamatsu K; Department of Analytic Human Pathology, Nippon Medical School, 1-25-16, Nezu, Bunkyo-ku, Tokyo, 113-0031, Japan.
Kuwahara N; Department of Analytic Human Pathology, Nippon Medical School, 1-25-16, Nezu, Bunkyo-ku, Tokyo, 113-0031, Japan.
Yoneyama K; Department of Obstetrics and Gynecology, Nippon Medical School Musashikosugi Hospital, 1-396, Kosugimachi, Nakahara-ku, Kawasaki, Kanagawa, 211-8533, Japan.; Minatomirai-Yume Clinic, 3-6-3, Minatomirai, Nishi-ku, Yokohama, Kanagawa, 220-0012, Japan.
Kawase R; Department of Obstetrics and Gynecology, Nippon Medical School Hospital, 1-1-5, Sendagi, Bunkyo-ku, Tokyo, 113-8602, Japan.
Kurose K; Department of Obstetrics and Gynecology, Nippon Medical School Hospital, 1-1-5, Sendagi, Bunkyo-ku, Tokyo, 113-8602, Japan.; Kubonoya Women's Hospital, 2-2-12, Chuou, Kashiwa, Chiba, 277-0023, Japan.
Toda E; Department of Analytic Human Pathology, Nippon Medical School, 1-25-16, Nezu, Bunkyo-ku, Tokyo, 113-0031, Japan.
Endo Y; Department of Analytic Human Pathology, Nippon Medical School, 1-25-16, Nezu, Bunkyo-ku, Tokyo, 113-0031, Japan.
Kunugi S; Department of Analytic Human Pathology, Nippon Medical School, 1-25-16, Nezu, Bunkyo-ku, Tokyo, 113-0031, Japan.
Kajimoto Y; Department of Analytic Human Pathology, Nippon Medical School, 1-25-16, Nezu, Bunkyo-ku, Tokyo, 113-0031, Japan.
Shimizu A; Department of Analytic Human Pathology, Nippon Medical School, 1-25-16, Nezu, Bunkyo-ku, Tokyo, 113-0031, Japan.
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Źródło :
Virchows Archiv : an international journal of pathology [Virchows Arch] 2021 May; Vol. 478 (5), pp. 893-904. Date of Electronic Publication: 2021 Jan 06.
Typ publikacji :
Journal Article
MeSH Terms :
Biomarkers, Tumor/*analysis
Core Binding Factor Alpha 1 Subunit/*analysis
Giant Cells/*chemistry
Leiomyosarcoma/*chemistry
Osteoclasts/*chemistry
RANK Ligand/*analysis
Uterine Neoplasms/*chemistry
Adult ; Aged ; Aged, 80 and over ; Biomarkers, Tumor/genetics ; Cathepsin K/analysis ; Cell Differentiation ; Core Binding Factor Alpha 1 Subunit/genetics ; Female ; Giant Cells/pathology ; Humans ; Leiomyosarcoma/genetics ; Leiomyosarcoma/secondary ; Middle Aged ; NFATC Transcription Factors/analysis ; Osteoclasts/pathology ; Phenotype ; RANK Ligand/genetics ; Up-Regulation ; Uterine Neoplasms/genetics ; Uterine Neoplasms/pathology
Czasopismo naukowe
Tytuł :
Cigarettes Make You Weak: RANKL/RANK Link Changes in Muscle and Bone.
Autorzy :
Nogueira L; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine University of California San Diego La Jolla, California and.; Instituto de Bioquímica Médica Leopoldo de Meis Universidade Federal do Rio de Janeiro Rio de Janeiro, Brazil.
Breen EC; Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine University of California San Diego La Jolla, California and.
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Źródło :
American journal of respiratory cell and molecular biology [Am J Respir Cell Mol Biol] 2021 May; Vol. 64 (5), pp. 533-535.
Typ publikacji :
Editorial; Research Support, Non-U.S. Gov't; Comment
MeSH Terms :
RANK Ligand*
Tobacco Products*
Bone and Bones ; Muscles
Raport
Tytuł :
Ortho-silicic Acid Inhibits RANKL-Induced Osteoclastogenesis and Reverses Ovariectomy-Induced Bone Loss In Vivo.
Autorzy :
Ma W; Department of Spine Surgery, Qilu Hospital of Shandong University, Jinan, China.
Wang F; Department of Spine Surgery, Qilu Hospital of Shandong University, Jinan, China.
You Y; Department of Spine Surgery, Qilu Hospital of Shandong University, Jinan, China.
Wu W; Department of Spine Surgery, Qilu Hospital of Shandong University, Jinan, China.
Chi H; Department of traumatic Orthopedics, West Branch of Shandong Provincial Hospital, Jinan, China.
Jiao G; Department of Spine Surgery, Qilu Hospital of Shandong University, Jinan, China.
Zhang L; Department of Spine Surgery, Qilu Hospital of Shandong University, Jinan, China.
Zhou H; Department of Spine Surgery, Linyi Central Hospital, Linyi, China.
Wang H; Department of Spine Surgery, Qilu Hospital of Shandong University, Jinan, China.
Chen Y; Department of Spine Surgery, Qilu Hospital of Shandong University, Jinan, China. .
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Źródło :
Biological trace element research [Biol Trace Elem Res] 2021 May; Vol. 199 (5), pp. 1864-1876. Date of Electronic Publication: 2020 Jul 16.
Typ publikacji :
Journal Article
MeSH Terms :
Bone Resorption*/drug therapy
RANK Ligand*
Animals ; Cell Differentiation ; Female ; Humans ; NF-kappa B ; Osteogenesis ; Ovariectomy ; Rats ; Silicic Acid
Czasopismo naukowe
Tytuł :
β-Boswellic Acid Inhibits RANKL-Induced Osteoclast Differentiation and Function by Attenuating NF-κB and Btk-PLCγ2 Signaling Pathways.
Autorzy :
Park GD; Musculoskeletal and Immune Disease Research Institute, School of Medicine, Wonkwang University, 460 Iksandae-ro, Iksan, Jeonbuk 54538, Korea.
Cheon YH; Musculoskeletal and Immune Disease Research Institute, School of Medicine, Wonkwang University, 460 Iksandae-ro, Iksan, Jeonbuk 54538, Korea.
Eun SY; Musculoskeletal and Immune Disease Research Institute, School of Medicine, Wonkwang University, 460 Iksandae-ro, Iksan, Jeonbuk 54538, Korea.
Lee CH; Musculoskeletal and Immune Disease Research Institute, School of Medicine, Wonkwang University, 460 Iksandae-ro, Iksan, Jeonbuk 54538, Korea.; Division of Rheumatology, Department of Internal Medicine, Wonkwang University Hospital, 460 Iksandae-ro, Iksan, Jeonbuk 54538, Korea.
Lee MS; Musculoskeletal and Immune Disease Research Institute, School of Medicine, Wonkwang University, 460 Iksandae-ro, Iksan, Jeonbuk 54538, Korea.; Division of Rheumatology, Department of Internal Medicine, Wonkwang University Hospital, 460 Iksandae-ro, Iksan, Jeonbuk 54538, Korea.
Kim JY; Musculoskeletal and Immune Disease Research Institute, School of Medicine, Wonkwang University, 460 Iksandae-ro, Iksan, Jeonbuk 54538, Korea.
Cho HJ; Musculoskeletal and Immune Disease Research Institute, School of Medicine, Wonkwang University, 460 Iksandae-ro, Iksan, Jeonbuk 54538, Korea.; Department of Obstetrics and Gynecology, Wonkwang University Hospital, Iksan 54538, Korea.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 May 01; Vol. 26 (9). Date of Electronic Publication: 2021 May 01.
Typ publikacji :
Journal Article
MeSH Terms :
Bone Resorption*
Gene Expression Regulation*
RANK Ligand*
Agammaglobulinaemia Tyrosine Kinase/*metabolism
Osteoclasts/*metabolism
Phospholipase C gamma/*metabolism
Triterpenes/*pharmacology
Animals ; Boswellia ; Cell Differentiation ; Coculture Techniques ; Male ; Mice ; Mice, Inbred ICR ; NF-kappa B/metabolism ; Osteoblasts/metabolism ; Osteogenesis/drug effects ; Osteoporosis/metabolism ; Phosphorylation ; Signal Transduction
Czasopismo naukowe
Tytuł :
Glutamine metabolite α-ketoglutarate acts as an epigenetic co-factor to interfere with osteoclast differentiation.
Autorzy :
Lee S; School of Medicine, Konkuk University, Seoul, South Korea.
Kim HS; Department of Biomedical Sciences, College of Natural Science, Dong-A University, Busan, South Korea; Department of Health Sciences, The Graduate School of Dong-A University, Busan, South Korea.
Kim MJ; School of Medicine, Konkuk University, Seoul, South Korea.
Min KY; School of Medicine, Konkuk University, Seoul, South Korea.
Choi WS; School of Medicine, Konkuk University, Seoul, South Korea; Research Institute of Medical Science, KU Open Innovation Center, Konkuk University, Seoul, South Korea.
You JS; School of Medicine, Konkuk University, Seoul, South Korea; Research Institute of Medical Science, KU Open Innovation Center, Konkuk University, Seoul, South Korea. Electronic address: .
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Źródło :
Bone [Bone] 2021 Apr; Vol. 145, pp. 115836. Date of Electronic Publication: 2020 Dec 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Osteoclasts*/metabolism
RANK Ligand*/metabolism
Animals ; Cell Differentiation ; Epigenesis, Genetic ; Glutamine ; Ketoglutaric Acids ; Mice ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł :
Postnatal expression and possible function of RANK and RANKL in the murine inner ear.
Autorzy :
Kao SY; Department of Otolaryngology - Head and Neck Surgery, Massachusetts Eye and Ear, Boston, MA 02114, USA.
Katsumi S; Department of Otolaryngology - Head and Neck Surgery, Massachusetts Eye and Ear, Boston, MA 02114, USA; Department of Otolaryngology - Head and Neck Surgery, Harvard Medical School, Boston, MA 02115, USA.
Han D; Department of Otolaryngology - Head and Neck Surgery, Massachusetts Eye and Ear, Boston, MA 02114, USA; Department of Otolaryngology - Head and Neck Surgery, Harvard Medical School, Boston, MA 02115, USA.
Bizaki-Vallaskangas AJ; Department of Otolaryngology - Head and Neck Surgery, Massachusetts Eye and Ear, Boston, MA 02114, USA.
Vasilijic S; Department of Otolaryngology - Head and Neck Surgery, Massachusetts Eye and Ear, Boston, MA 02114, USA; Department of Otolaryngology - Head and Neck Surgery, Harvard Medical School, Boston, MA 02115, USA.
Landegger LD; Department of Otolaryngology - Head and Neck Surgery, Massachusetts Eye and Ear, Boston, MA 02114, USA; Department of Otolaryngology - Head and Neck Surgery, Harvard Medical School, Boston, MA 02115, USA.
Kristiansen AG; Department of Otolaryngology - Head and Neck Surgery, Massachusetts Eye and Ear, Boston, MA 02114, USA.
McKenna MJ; Department of Otolaryngology - Head and Neck Surgery, Massachusetts Eye and Ear, Boston, MA 02114, USA; Department of Otolaryngology - Head and Neck Surgery, Harvard Medical School, Boston, MA 02115, USA; Speech and Hearing Bioscience and Technology Program, Harvard Medical School, Boston, MA 02115, USA.
Stankovic KM; Department of Otolaryngology - Head and Neck Surgery, Massachusetts Eye and Ear, Boston, MA 02114, USA; Department of Otolaryngology - Head and Neck Surgery, Harvard Medical School, Boston, MA 02115, USA; Speech and Hearing Bioscience and Technology Program, Harvard Medical School, Boston, MA 02115, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA; Program in Therapeutic Science, Harvard Medical School, Boston, MA 02115, USA. Electronic address: .
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Źródło :
Bone [Bone] 2021 Apr; Vol. 145, pp. 115837. Date of Electronic Publication: 2020 Dec 29.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Ear, Inner*
RANK Ligand*
Animals ; Bone Remodeling ; Mice ; Nogo Proteins ; Osteoprotegerin/genetics ; Receptor Activator of Nuclear Factor-kappa B
Czasopismo naukowe
Tytuł :
Icariin reduces bone loss in a Rankl-induced transgenic medaka (Oryzias latipes) model for osteoporosis.
Autorzy :
Pham CV; Faculty of Biology, VNU University of Science, Vietnam National University, Hanoi, Vietnam.
Pham TT; Faculty of Biology, VNU University of Science, Vietnam National University, Hanoi, Vietnam.
Lai TT; Faculty of Biology, VNU University of Science, Vietnam National University, Hanoi, Vietnam.
Trinh DC; Faculty of Biology, VNU University of Science, Vietnam National University, Hanoi, Vietnam.
Nguyen HVM; Faculty of Biology, VNU University of Science, Vietnam National University, Hanoi, Vietnam.
Ha TTM; Faculty of Biology, VNU University of Science, Vietnam National University, Hanoi, Vietnam.
Phuong TT; Department of Herbal Analysis and Standardization, Vietnam National Institute of Medicinal Materials, Hanoi, Vietnam.
Tran LD; Faculty of Biology, VNU University of Science, Vietnam National University, Hanoi, Vietnam.; The Key Laboratory of Enzyme and Protein Technology, VNU University of Science, Hanoi, Vietnam.
Winkler C; Department of Biological Sciences and Centre for Bioimaging Sciences, National University of Singapore, Singapore.
To TT; Faculty of Biology, VNU University of Science, Vietnam National University, Hanoi, Vietnam.; The Key Laboratory of Enzyme and Protein Technology, VNU University of Science, Hanoi, Vietnam.; Dinh Tien Hoang Institute of Medicine, Hanoi, Vietnam.
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Źródło :
Journal of fish biology [J Fish Biol] 2021 Apr; Vol. 98 (4), pp. 1039-1048. Date of Electronic Publication: 2020 Jan 09.
Typ publikacji :
Journal Article
MeSH Terms :
Disease Models, Animal*
Fish Diseases/*chemically induced
Flavonoids/*adverse effects
Oryzias/*genetics
Osteoporosis/*chemically induced
RANK Ligand/*metabolism
Alendronate/therapeutic use ; Animals ; Bone Density Conservation Agents/therapeutic use ; Etidronic Acid/therapeutic use ; Organisms, Genetically Modified ; RANK Ligand/genetics
Czasopismo naukowe
Tytuł :
SLPI in periodontal Ligament is not sleepy during biophysical force-induced tooth movement.
Autorzy :
Lee SY; Dental Science Research Institute, School of Dentistry, Chonnam National University, Gwangju, Korea.
Moon JS; Dental Science Research Institute, School of Dentistry, Chonnam National University, Gwangju, Korea.
Yang DW; Dental Science Research Institute, School of Dentistry, Chonnam National University, Gwangju, Korea.
Yoo HI; Department of Anatomy and Neuroscience, College of Medicine, Eulji University, Daejeon, Korea.
Jung JY; Dental Science Research Institute, School of Dentistry, Chonnam National University, Gwangju, Korea.
Kim OS; Dental Science Research Institute, School of Dentistry, Chonnam National University, Gwangju, Korea.
Kim MS; Dental Science Research Institute, School of Dentistry, Chonnam National University, Gwangju, Korea.
Koh JT; Dental Science Research Institute, School of Dentistry, Chonnam National University, Gwangju, Korea.
Chung HJ; Dental Science Research Institute, School of Dentistry, Chonnam National University, Gwangju, Korea.
Kim SH; Dental Science Research Institute, School of Dentistry, Chonnam National University, Gwangju, Korea.
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Źródło :
Journal of clinical periodontology [J Clin Periodontol] 2021 Apr; Vol. 48 (4), pp. 528-540. Date of Electronic Publication: 2021 Jan 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Periodontal Ligament*
RANK Ligand*
Animals ; Cells, Cultured ; Rats ; Secretory Leukocyte Peptidase Inhibitor ; Tooth Movement Techniques
Czasopismo naukowe
Tytuł :
Effect of periostin silencing on Runx2, RANKL and OPG expression in osteoblasts.
Autorzy :
Cai J; Department of Anesthesia, Maternal and Child Health Hospital of Lianyungang City, Lianyungang City, Jiangsu Province, China. .
Qin H; Department of Stomatology, Lianyungang Affiliated Hospital of Xuzhou Medical University, Lianyungang City, Jiangsu Province, China.
Yu G; Department of Anesthesia, Maternal and Child Health Hospital of Lianyungang City, Lianyungang City, Jiangsu Province, China.
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Transliterated Title :
Wirkung von Periostin-Silencing auf die Expression von Runx2, RANKL und OPG in Osteoblasten.
Źródło :
Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie [J Orofac Orthop] 2021 Mar; Vol. 82 (2), pp. 82-91. Date of Electronic Publication: 2020 Nov 03.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Adhesion Molecules*/physiology
Osteoblasts*
RANK Ligand*/genetics
Animals ; Cell Differentiation ; Core Binding Factor Alpha 1 Subunit ; Mice ; Osteoclasts ; Osteogenesis ; Osteoprotegerin/genetics ; Tooth Eruption
Czasopismo naukowe
Tytuł :
Anacardic acid-mediated regulation of osteoblast differentiation involves mitigation of inflammasome activation pathways.
Autorzy :
Venugopal M; Amrita School of Biotechnology, Amrita Vishwa Vidyapeetham, Amritapuri, Clappana P.O, Kollam, Kerala, India, 690525.
Nambiar J; Amrita School of Biotechnology, Amrita Vishwa Vidyapeetham, Amritapuri, Clappana P.O, Kollam, Kerala, India, 690525.
Nair BG; Amrita School of Biotechnology, Amrita Vishwa Vidyapeetham, Amritapuri, Clappana P.O, Kollam, Kerala, India, 690525. .
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Źródło :
Molecular and cellular biochemistry [Mol Cell Biochem] 2021 Feb; Vol. 476 (2), pp. 819-829. Date of Electronic Publication: 2020 Oct 22.
Typ publikacji :
Journal Article
MeSH Terms :
Anacardic Acids/*pharmacology
Bone Diseases/*drug therapy
Inflammasomes/*antagonists & inhibitors
Osteoblasts/*drug effects
Osteocalcin/*agonists
RANK Ligand/*agonists
Bone Diseases/metabolism ; Bone Diseases/pathology ; Cell Differentiation/drug effects ; Cell Line, Tumor ; Humans ; Inflammasomes/metabolism ; NF-kappa B/antagonists & inhibitors ; Osteoblasts/metabolism ; Osteocalcin/metabolism ; RANK Ligand/metabolism
Czasopismo naukowe
Tytuł :
Effects of long-term antiepileptic polytherapy on bone biochemical markers in ambulatory children and adolescents and possible benefits of vitamin D supplementation: a prospective interventional study.
Autorzy :
Papassava M; Department of Pediatrics, 'G. Hatzikosta Hospital', Ioannina, Greece. Electronic address: .
Siomou E; Division of Pediatric Nephrology, Department of Pediatrics, University Hospital of Ioannina, Ioannina 451 10, Greece.
Nakou I; Division of Pediatric Neurology, University Hospital of Ioannina, Ioannina 451 10, Greece.
Cholevas V; Pediatric Research Laboratory, University of Ioannina, Ioannina 451 10, Greece.
Challa A; Pediatric Research Laboratory, University of Ioannina, Ioannina 451 10, Greece.
Tzoufi M; Division of Pediatric Nephrology, Department of Pediatrics, University Hospital of Ioannina, Ioannina 451 10, Greece.
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Źródło :
Epilepsy & behavior : E&B [Epilepsy Behav] 2021 Feb; Vol. 115, pp. 107708. Date of Electronic Publication: 2021 Jan 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anticonvulsants*/therapeutic use
RANK Ligand*
Adolescent ; Biomarkers ; Child ; Dietary Supplements ; Humans ; Prospective Studies ; Vitamin D
Czasopismo naukowe
Tytuł :
Inhibition of RANKL-Induced Osteoclastogenesis by Novel Mutant RANKL.
Autorzy :
Jang Y; Laboratory of Orthopaedic Research, Chosun University Hospital, Dong-Gu, Gwangju 61452, Korea.; Department of Orthopaedic Surgery, Chosun University Hospital, Dong-Gu, Gwangju 61452, Korea.
Sohn HM; Laboratory of Orthopaedic Research, Chosun University Hospital, Dong-Gu, Gwangju 61452, Korea.; Department of Orthopaedic Surgery, Chosun University Hospital, Dong-Gu, Gwangju 61452, Korea.
Ko YJ; Laboratory of Orthopaedic Research, Chosun University Hospital, Dong-Gu, Gwangju 61452, Korea.; Department of Orthopaedic Surgery, Chosun University Hospital, Dong-Gu, Gwangju 61452, Korea.
Hyun H; Department of Biomedical Sciences Chonnam National University Medical School, Gwangju 61469, Korea.
Lim W; Laboratory of Orthopaedic Research, Chosun University Hospital, Dong-Gu, Gwangju 61452, Korea.; Department of Orthopaedic Surgery, Chosun University Hospital, Dong-Gu, Gwangju 61452, Korea.; Department of Premedical Science, College of Medicine, Chosun University, Dong-Gu, Gwangju 61452, Korea.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jan 04; Vol. 22 (1). Date of Electronic Publication: 2021 Jan 04.
Typ publikacji :
Journal Article
MeSH Terms :
Mutation*
Osteogenesis*
Mutant Proteins/*metabolism
Osteoclasts/*cytology
RANK Ligand/*metabolism
Animals ; Cells, Cultured ; Female ; Mice ; Mice, Inbred C57BL ; Mutant Proteins/administration & dosage ; Mutant Proteins/genetics ; Osteoclasts/metabolism ; RANK Ligand/genetics ; Signal Transduction
Czasopismo naukowe
Tytuł :
Triterpenoids from Celastrus orbiculatus Thunb. inhibit RANKL-induced osteoclast formation and bone resorption via c-Fos signaling.
Autorzy :
Vu TO; College of Pharmacy, Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu, 41566, Republic of Korea.
Tran PT; Department of Biochemistry, College of Natural Sciences, Kangwon National University, Chuncheon, Gangwon-Do, 24341, Republic of Korea.
Seo W; Department of Biochemistry, College of Natural Sciences, Kangwon National University, Chuncheon, Gangwon-Do, 24341, Republic of Korea.
Lee JH; Department of Biochemistry, College of Natural Sciences, Kangwon National University, Chuncheon, Gangwon-Do, 24341, Republic of Korea.
Min BS; College of Pharmacy, Drug Research and Development Center, Daegu Catholic University, Gyeongsan, 38430, Republic of Korea.
Kim JA; College of Pharmacy, Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu, 41566, Republic of Korea. .
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Źródło :
Journal of natural medicines [J Nat Med] 2021 Jan; Vol. 75 (1), pp. 56-65. Date of Electronic Publication: 2020 Aug 10.
Typ publikacji :
Journal Article
MeSH Terms :
Bone Resorption/*drug therapy
Osteoclasts/*drug effects
Proto-Oncogene Proteins c-fos/*metabolism
RANK Ligand/*antagonists & inhibitors
Triterpenes/*pharmacology
Animals ; Bone Resorption/metabolism ; Bone Resorption/pathology ; Celastrus/chemistry ; Cell Differentiation/drug effects ; Male ; Mice ; Mice, Inbred ICR ; Osteoclasts/metabolism ; Osteoclasts/pathology ; Plant Extracts/isolation & purification ; Plant Extracts/pharmacology ; RANK Ligand/metabolism ; Signal Transduction/drug effects ; Triterpenes/isolation & purification
Czasopismo naukowe
Tytuł :
TNF Receptor: Fc Fusion Protein Downregulates RANKL/OPG Ratio by Inhibiting CXCL16/CXCR6 in Active Ankylosing Spondylitis.
Autorzy :
Zhang P; Department of Rheumatology and Immunology, Jinan Central Hospital Affiliated to Shandong University, Jinan 250013, China.
Zhou S; Department of Rheumatology and Immunology, Southern Medical University Affiliated Shenzhen Baoan Hospital, Shenzhen 518101, China.
Chen Z; Department of Rheumatology and Immunology, Southern Medical University Affiliated Shenzhen Baoan Hospital, Shenzhen 518101, China.
Tian Y; Department of Rheumatology and Immunology, Southern Medical University Affiliated Shenzhen Baoan Hospital, Shenzhen 518101, China.
Wang Q; Department of Rheumatology and Immunology, Southern Medical University Affiliated Shenzhen Baoan Hospital, Shenzhen 518101, China.
Li H; Department of Rheumatology and Immunology, Southern Medical University Affiliated Shenzhen Baoan Hospital, Shenzhen 518101, China.
Zhang T; Department of Rheumatology and Immunology, Southern Medical University Affiliated Shenzhen Baoan Hospital, Shenzhen 518101, China.
Guo Q; Department of Rheumatology and Immunology, Southern Medical University Affiliated Shenzhen Baoan Hospital, Shenzhen 518101, China.
Wang M; Department of Rheumatology and Immunology, Peking University Shenzhen Hospital, Shenzhen 518000, China.
Guo C; Department of Rheumatology and Immunology, Southern Medical University Affiliated Shenzhen Baoan Hospital, Shenzhen 518101, China.
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Źródło :
Current pharmaceutical biotechnology [Curr Pharm Biotechnol] 2021; Vol. 22 (2), pp. 305-316.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Chemokine CXCL16/*antagonists & inhibitors
Etanercept/*administration & dosage
Osteoprotegerin/*antagonists & inhibitors
RANK Ligand/*antagonists & inhibitors
Receptors, CXCR6/*antagonists & inhibitors
Spondylitis, Ankylosing/*drug therapy
Adolescent ; Adult ; Chemokine CXCL16/metabolism ; Down-Regulation/drug effects ; Down-Regulation/physiology ; Female ; Humans ; Injections, Subcutaneous ; Male ; Middle Aged ; Osteoprotegerin/metabolism ; RANK Ligand/metabolism ; Receptors, CXCR6/metabolism ; Spondylitis, Ankylosing/metabolism ; Young Adult
Czasopismo naukowe
Tytuł :
Determinants of Periodontal/Periapical Lesion Stability and Progression.
Autorzy :
Cavalla F; Department of Conservative Dentistry, School of Dentistry, University of Chile, Santiago, Chile.
Letra A; Department of Diagnostic and Biomedical Sciences, University of Texas Health Science Center School of Dentistry, Houston, TX, USA.; Center for Craniofacial Research, University of Texas Health Science Center School of Dentistry, Houston, TX, USA.; Pediatric Research Center, University of Texas Health Science Center at Houston McGovern Medical School, Houston, TX, USA.
Silva RM; Center for Craniofacial Research, University of Texas Health Science Center School of Dentistry, Houston, TX, USA.; Pediatric Research Center, University of Texas Health Science Center at Houston McGovern Medical School, Houston, TX, USA.; Department of Endodontics, University of Texas Health Science Center School of Dentistry, Houston, TX, USA.
Garlet GP; OSTEOimmunology Laboratory, Department of Biological Sciences, School of Dentistry of Bauru, São Paulo University-FOB/USP, Bauru, SP, Brazil.
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Źródło :
Journal of dental research [J Dent Res] 2021 Jan; Vol. 100 (1), pp. 29-36. Date of Electronic Publication: 2020 Aug 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Osteoprotegerin*
RANK Ligand*
Chronic Disease ; Cytokines ; Humans ; Th17 Cells
Czasopismo naukowe
Tytuł :
The effect of low-level laser radiation and doxycycline on the levels of osteoprotegerin and receptor activator of nuclear factor kappa-B ligand.
Autorzy :
Farhad SZ; School of Dentistry, Islamic Azad University, Khorasgan Branch, Isfahan, Iran.
Siadat A; School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.
Sadeghian N; School of Dentistry, Islamic Azad University, Khorasgan Branch, Isfahan, Iran.
Abrishamkar S; School of Dentistry, Islamic Azad University, Khorasgan Branch, Isfahan, Iran. .
Khosraviani F; School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
Khazaei P; School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
Saberi-Demneh A; School of Medicine, Semnan University of Medical Sciences, Semnan, Iran.
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Źródło :
Lasers in medical science [Lasers Med Sci] 2020 Dec; Vol. 35 (9), pp. 1975-1979. Date of Electronic Publication: 2020 Mar 27.
Typ publikacji :
Journal Article
MeSH Terms :
Low-Level Light Therapy*
Doxycycline/*pharmacology
Osteoprotegerin/*metabolism
RANK Ligand/*metabolism
Cell Line, Tumor ; Gene Expression Regulation/drug effects ; Gene Expression Regulation/radiation effects ; Humans ; Osteoclasts/cytology ; Osteoprotegerin/genetics ; RANK Ligand/genetics
Czasopismo naukowe
Tytuł :
Histomorphometric Analysis of Pre- and Post-Denosumab-Treated Giant Cell Tumor of Bone.
Autorzy :
Ud Din N; Aga Khan University Hospital, Karachi, Pakistan.
Umer M; Aga Khan University Hospital, Karachi, Pakistan.
Park YK; Korea Clinical Laboratory, Seoul, Korea.
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Źródło :
International journal of surgical pathology [Int J Surg Pathol] 2020 Dec; Vol. 28 (8), pp. 859-867. Date of Electronic Publication: 2020 May 19.
Typ publikacji :
Journal Article
MeSH Terms :
Bone Neoplasms/*therapy
Denosumab/*administration & dosage
Giant Cell Tumor of Bone/*therapy
Neoplasm Recurrence, Local/*therapy
RANK Ligand/*antagonists & inhibitors
Adolescent ; Adult ; Aged ; Biomarkers, Tumor/analysis ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Bone Neoplasms/genetics ; Bone Neoplasms/pathology ; Bone and Bones/drug effects ; Bone and Bones/pathology ; Bone and Bones/surgery ; Chemotherapy, Adjuvant/methods ; Female ; Gene Expression Regulation, Neoplastic/drug effects ; Giant Cell Tumor of Bone/genetics ; Giant Cell Tumor of Bone/pathology ; Histones/analysis ; Histones/genetics ; Histones/metabolism ; Humans ; Immunohistochemistry ; Injections, Subcutaneous ; Male ; Margins of Excision ; Matrix Attachment Region Binding Proteins/analysis ; Matrix Attachment Region Binding Proteins/genetics ; Matrix Attachment Region Binding Proteins/metabolism ; Middle Aged ; Neoplasm Recurrence, Local/genetics ; Neoplasm Recurrence, Local/pathology ; Osteoblasts/drug effects ; Osteogenesis/drug effects ; Osteotomy ; RANK Ligand/metabolism ; Transcription Factors/analysis ; Transcription Factors/genetics ; Transcription Factors/metabolism ; Young Adult
Czasopismo naukowe

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