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Tytuł :
Sex and Age-Related Differences in Neuroinflammation and Apoptosis in Balb/c Mice Retina Involve Resolvin D1.
Autorzy :
Trotta MC; Section of Pharmacology, Department of Experimental Medicine, University of Campania 'Luigi Vanvitelli', via Santa Maria di Costantinopoli 16, 80138 Naples, Italy.
Gharbia S; 'Aurel Ardelean' Institute of Life Sciences, Vasile Goldis Western University of Arad, 86 Revolutiei Av., 310144 Arad, Romania.
Herman H; 'Aurel Ardelean' Institute of Life Sciences, Vasile Goldis Western University of Arad, 86 Revolutiei Av., 310144 Arad, Romania.
Mladin B; 'Aurel Ardelean' Institute of Life Sciences, Vasile Goldis Western University of Arad, 86 Revolutiei Av., 310144 Arad, Romania.
Hermenean A; Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 8 Eroii Sanitari Av., 050474 Bucharest, Romania.
Balta C; 'Aurel Ardelean' Institute of Life Sciences, Vasile Goldis Western University of Arad, 86 Revolutiei Av., 310144 Arad, Romania.
Cotoraci C; Faculty of Medicine, Vasile Goldis Western University of Arad, 86 Revolutiei Av., 310144 Arad, Romania.
Peteu VE; Victor Babes National Institute of Pathology, 99-101 Splaiul Independentei Av., 050096 Bucharest, Romania.
Gesualdo C; Eye Clinic, Multidisciplinary Department of Medical, Surgical and Dental Sciences, University of Campania 'Luigi Vanvitelli', Via Luigi De Crecchio 6, 80138 Naples, Italy.
Petrillo F; Department of Ophthalmology, University of Catania, P.zza Università 2, 95131 Catania, Italy.
Galdiero M; Section of Pharmacology, Department of Experimental Medicine, University of Campania 'Luigi Vanvitelli', via Santa Maria di Costantinopoli 16, 80138 Naples, Italy.
Alfano R; Department of Advanced Medical and Surgical Sciences 'DAMSS', University of Campania 'Luigi Vanvitelli', P.zza L. Miraglia 2, 80138 Naples, Italy.
Gherghiceanu M; Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 8 Eroii Sanitari Av., 050474 Bucharest, Romania.; Victor Babes National Institute of Pathology, 99-101 Splaiul Independentei Av., 050096 Bucharest, Romania.
D'Amico M; Section of Pharmacology, Department of Experimental Medicine, University of Campania 'Luigi Vanvitelli', via Santa Maria di Costantinopoli 16, 80138 Naples, Italy.
Rossi S; Eye Clinic, Multidisciplinary Department of Medical, Surgical and Dental Sciences, University of Campania 'Luigi Vanvitelli', Via Luigi De Crecchio 6, 80138 Naples, Italy.
Hermenean A; 'Aurel Ardelean' Institute of Life Sciences, Vasile Goldis Western University of Arad, 86 Revolutiei Av., 310144 Arad, Romania.; Faculty of Medicine, Vasile Goldis Western University of Arad, 86 Revolutiei Av., 310144 Arad, Romania.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jun 11; Vol. 22 (12). Date of Electronic Publication: 2021 Jun 11.
Typ publikacji :
Journal Article
MeSH Terms :
Sex Characteristics*
Aging/*pathology
Docosahexaenoic Acids/*pharmacology
Inflammation/*pathology
Retina/*pathology
Animals ; Apoptosis/drug effects ; Biomarkers/metabolism ; Caspase 3/metabolism ; Ependymoglial Cells/drug effects ; Ependymoglial Cells/metabolism ; Ependymoglial Cells/pathology ; Ependymoglial Cells/ultrastructure ; Female ; Male ; Mice, Inbred BALB C ; Microglia/drug effects ; Microglia/metabolism ; Microglia/pathology ; Microglia/ultrastructure ; NF-kappa B/metabolism ; Retina/drug effects ; Tumor Necrosis Factor-alpha/metabolism ; Tyrosine/analogs & derivatives ; Tyrosine/metabolism
Czasopismo naukowe
Tytuł :
TPTEP1 suppresses high glucose-induced dysfunction in retinal vascular endothelial cells by interacting with STAT3 and targeting VEGFA.
Autorzy :
Sun X; Department of Ophthalmology, Zhengzhou Central Hospital Affiliated To Zhengzhou University, Zhengzhou, 450001, Henan, China.
Lu Y; Department of Ophthalmology, Henan Children's Hospital, Children's Hospital Affiliated of Zhengzhou University, Zhengzhou, 450053, Henan, China.
Lei T; Department of Endocrinology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, No. 164, Lanxi Road, Shanghai, 200062, China. .
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Źródło :
Acta diabetologica [Acta Diabetol] 2021 Jun; Vol. 58 (6), pp. 759-769. Date of Electronic Publication: 2021 Feb 12.
Typ publikacji :
Journal Article
MeSH Terms :
Endothelial Cells/*drug effects
Glucose/*pharmacology
RNA, Long Noncoding/*physiology
Retina/*drug effects
Cell Proliferation/genetics ; Cells, Cultured ; Down-Regulation/drug effects ; Down-Regulation/genetics ; Endothelial Cells/physiology ; Gene Expression Regulation/drug effects ; Humans ; Neovascularization, Pathologic/genetics ; Neovascularization, Pathologic/metabolism ; Neovascularization, Pathologic/pathology ; Neovascularization, Pathologic/physiopathology ; Protein Binding/drug effects ; RNA, Long Noncoding/genetics ; Retina/metabolism ; Retina/physiopathology ; STAT3 Transcription Factor/genetics ; STAT3 Transcription Factor/metabolism ; Signal Transduction/drug effects ; Signal Transduction/genetics ; Vascular Endothelial Growth Factor A/genetics ; Vascular Endothelial Growth Factor A/metabolism
Czasopismo naukowe
Tytuł :
Compatibility of intravitreally applied epidermal growth factor and amphiregulin.
Autorzy :
Bikbov MM; Ufa Eye Research Institute, Ufa, Bashkortostan, Russia.
Khalimov TA; Ufa Eye Research Institute, Ufa, Bashkortostan, Russia.
Cerrada-Gimenez M; Experimentica Ltd, Kuopio, Finland.
Ragauskas S; Experimentica Ltd, Kuopio, Finland.
Kalesnykas G; Experimentica Ltd, Kuopio, Finland.
Jonas JB; Department of Ophthalmology, Medical Faculty Mannheim, Heidelberg University, Universitäts-Augenklinik, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany. .; Institute of Clinical and Scientific Ophthalmology and Acupuncture Jonas and Panda, Heidelberg, Germany. .
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Źródło :
International ophthalmology [Int Ophthalmol] 2021 Jun; Vol. 41 (6), pp. 2053-2063. Date of Electronic Publication: 2021 Mar 13.
Typ publikacji :
Journal Article
MeSH Terms :
Epidermal Growth Factor*
Retina*
Amphiregulin ; Animals ; Guinea Pigs ; Intraocular Pressure ; Intravitreal Injections ; Rabbits
Czasopismo naukowe
Tytuł :
Retinal Pigment Epithelium Remodeling in Mouse Models of Retinitis Pigmentosa.
Autorzy :
Napoli D; CNR Neuroscience Institute, 56124 Pisa, Italy.
Biagioni M; CNR Neuroscience Institute, 56124 Pisa, Italy.
Billeri F; CNR Neuroscience Institute, 56124 Pisa, Italy.; Department of Biology, University of Pisa, 56126 Pisa, Italy.
Di Marco B; CNR Neuroscience Institute, 56124 Pisa, Italy.
Orsini N; CNR Neuroscience Institute, 56124 Pisa, Italy.; Regional Doctorate School in Neuroscience, Universities of Florence, Pisa and Siena, 50139 Florence, Italy.
Novelli E; CNR Neuroscience Institute, 56124 Pisa, Italy.
Strettoi E; CNR Neuroscience Institute, 56124 Pisa, Italy.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 May 20; Vol. 22 (10). Date of Electronic Publication: 2021 May 20.
Typ publikacji :
Journal Article
MeSH Terms :
Retina/*physiopathology
Retinal Pigment Epithelium/*physiopathology
Retinitis Pigmentosa/*physiopathology
Animals ; Dexamethasone/pharmacology ; Disease Models, Animal ; Evaluation Studies as Topic ; Inflammation/metabolism ; Inflammation/physiopathology ; Mice ; Mice, Inbred C57BL ; Retina/drug effects ; Retina/metabolism ; Retinal Cone Photoreceptor Cells/drug effects ; Retinal Cone Photoreceptor Cells/metabolism ; Retinal Pigment Epithelium/drug effects ; Retinal Pigment Epithelium/metabolism ; Retinal Rod Photoreceptor Cells/drug effects ; Retinal Rod Photoreceptor Cells/metabolism ; Retinal Vessels/drug effects ; Retinal Vessels/metabolism ; Retinitis Pigmentosa/metabolism ; Rhodopsin/metabolism ; Tight Junctions/drug effects ; Tight Junctions/metabolism ; Zonula Occludens-1 Protein/metabolism
Czasopismo naukowe
Tytuł :
Delivery Systems of Retinoprotective Proteins in the Retina.
Autorzy :
Rebustini IT; Section of Protein Structure and Function, LRCMB-NEI-NIH, Bethesda, MD 20892-0608, USA.
Bernardo-Colón A; Section of Protein Structure and Function, LRCMB-NEI-NIH, Bethesda, MD 20892-0608, USA.
Nalvarte AI; Section of Protein Structure and Function, LRCMB-NEI-NIH, Bethesda, MD 20892-0608, USA.
Becerra SP; Section of Protein Structure and Function, LRCMB-NEI-NIH, Bethesda, MD 20892-0608, USA.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 May 19; Vol. 22 (10). Date of Electronic Publication: 2021 May 19.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Eye Proteins/*metabolism
Nerve Growth Factors/*metabolism
Retina/*metabolism
Retinal Pigment Epithelium/*metabolism
Serpins/*metabolism
Animals ; Endothelial Cells/metabolism ; Humans ; Photoreceptor Cells/metabolism ; Photoreceptor Cells, Vertebrate/metabolism ; Protein Transport/physiology ; Retina/physiology ; Retinal Degeneration/metabolism ; Retinal Neurons/metabolism
Czasopismo naukowe
Tytuł :
Effect of dual PPAR-α/γ agonist saroglitazar on diabetic retinopathy and oxygen-induced retinopathy.
Autorzy :
Joharapurkar A; Department of Pharmacology and Toxicology, Zydus Research Centre, Cadila Healthcare Limited, Sarkhej Bavla NH 8A, Moraiya, Ahmedabad, 382210, India. Electronic address: .
Patel V; Department of Pharmacology and Toxicology, Zydus Research Centre, Cadila Healthcare Limited, Sarkhej Bavla NH 8A, Moraiya, Ahmedabad, 382210, India.
Kshirsagar S; Department of Pharmacology and Toxicology, Zydus Research Centre, Cadila Healthcare Limited, Sarkhej Bavla NH 8A, Moraiya, Ahmedabad, 382210, India.
Patel MS; Department of Pharmacology and Toxicology, Zydus Research Centre, Cadila Healthcare Limited, Sarkhej Bavla NH 8A, Moraiya, Ahmedabad, 382210, India.
Savsani H; Department of Pharmacology and Toxicology, Zydus Research Centre, Cadila Healthcare Limited, Sarkhej Bavla NH 8A, Moraiya, Ahmedabad, 382210, India.
Jain M; Department of Pharmacology and Toxicology, Zydus Research Centre, Cadila Healthcare Limited, Sarkhej Bavla NH 8A, Moraiya, Ahmedabad, 382210, India.
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Źródło :
European journal of pharmacology [Eur J Pharmacol] 2021 May 15; Vol. 899, pp. 174032. Date of Electronic Publication: 2021 Mar 19.
Typ publikacji :
Journal Article
MeSH Terms :
Angiogenesis Inhibitors/*pharmacology
Diabetic Retinopathy/*drug therapy
PPAR alpha/*agonists
PPAR gamma/*agonists
Phenylpropionates/*pharmacology
Pyrroles/*pharmacology
Retina/*drug effects
Retinal Neovascularization/*drug therapy
Retinal Vessels/*drug effects
Animals ; Animals, Newborn ; Chick Embryo ; Diabetes Mellitus, Experimental/chemically induced ; Diabetic Retinopathy/etiology ; Diabetic Retinopathy/metabolism ; Diabetic Retinopathy/pathology ; Female ; Hyperoxia/complications ; Intercellular Adhesion Molecule-1/metabolism ; Male ; Neovascularization, Physiologic/drug effects ; Oxidative Stress/drug effects ; PPAR alpha/metabolism ; PPAR gamma/metabolism ; Rats, Sprague-Dawley ; Receptors, Vascular Endothelial Growth Factor/metabolism ; Retina/metabolism ; Retina/pathology ; Retinal Neovascularization/etiology ; Retinal Neovascularization/metabolism ; Retinal Neovascularization/pathology ; Retinal Vessels/metabolism ; Retinal Vessels/pathology ; Signal Transduction ; Streptozocin ; Transcription Factor RelA/metabolism
Czasopismo naukowe
Tytuł :
Molecular, Cellular and Functional Changes in the Retinas of Young Adult Mice Lacking the Voltage-Gated K Channel Subunits Kv8.2 and K2.1.
Autorzy :
Jiang X; Centre for Ophthalmology and Vision Science, The University of Western Australia, Perth, WA 6009, Australia.
Rashwan R; Lions Eye Institute, Nedlands, WA 6009, Australia.; Department of Microbiology and Immunology, Faculty of Medicine, Minia University, Minia 61519, Egypt.
Voigt V; Lions Eye Institute, Nedlands, WA 6009, Australia.
Nerbonne J; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Hunt DM; Centre for Ophthalmology and Vision Science, The University of Western Australia, Perth, WA 6009, Australia.; Lions Eye Institute, Nedlands, WA 6009, Australia.
Carvalho LS; Centre for Ophthalmology and Vision Science, The University of Western Australia, Perth, WA 6009, Australia.; Lions Eye Institute, Nedlands, WA 6009, Australia.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 May 05; Vol. 22 (9). Date of Electronic Publication: 2021 May 05.
Typ publikacji :
Journal Article
MeSH Terms :
Aging/*metabolism
Potassium Channels, Voltage-Gated/*metabolism
Protein Subunits/*metabolism
Retina/*cytology
Retina/*metabolism
Shab Potassium Channels/*metabolism
Animals ; Cell Death ; Electroretinography ; Gliosis/pathology ; Immunity ; Mice, Knockout ; Microglia/pathology ; Night Vision ; Retina/physiology
Czasopismo naukowe
Tytuł :
In vivo optoretinography of phototransduction activation and energy metabolism in retinal photoreceptors.
Autorzy :
Ma G; Department of Bioengineering, University of Illinois at Chicago, Chicago, Illinois, USA.
Son T; Department of Bioengineering, University of Illinois at Chicago, Chicago, Illinois, USA.
Kim TH; Department of Bioengineering, University of Illinois at Chicago, Chicago, Illinois, USA.
Yao X; Department of Bioengineering, University of Illinois at Chicago, Chicago, Illinois, USA.; Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois, USA.
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Źródło :
Journal of biophotonics [J Biophotonics] 2021 May; Vol. 14 (5), pp. e202000462. Date of Electronic Publication: 2021 Feb 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Photoreceptor Cells, Vertebrate*
Retina*/diagnostic imaging
Animals ; Energy Metabolism ; Light Signal Transduction ; Mice ; Tomography, Optical Coherence
Czasopismo naukowe
Tytuł :
Development of strategies to modulate gene expression of angiogenesis-related molecules in the retina.
Autorzy :
Araújo RS; iNOVA4Health, CEDOC, NOVA Medical School, Universidade Nova de, Lisboa, Campo Mártires da Pátria 130, 1169-056 Lisboa, Portugal; Bioengineering - Cell Therapies and Regenerative Medicine PhD Program, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, 1049-001 Lisboa, Portugal.
Bitoque DB; iNOVA4Health, CEDOC, NOVA Medical School, Universidade Nova de, Lisboa, Campo Mártires da Pátria 130, 1169-056 Lisboa, Portugal.
Silva GA; iNOVA4Health, CEDOC, NOVA Medical School, Universidade Nova de, Lisboa, Campo Mártires da Pátria 130, 1169-056 Lisboa, Portugal; NOVA Medical School, Universidade Nova de Lisboa, Campo Mártires da Pátria 130, 1169-056 Lisboa, Portugal. Electronic address: .
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Źródło :
Gene [Gene] 2021 Jul 30; Vol. 791, pp. 145724. Date of Electronic Publication: 2021 May 16.
Typ publikacji :
Journal Article
MeSH Terms :
Genetic Therapy/*methods
Retina/*metabolism
Retinal Neovascularization/*metabolism
Angiogenesis Inhibitors/metabolism ; Animals ; Cell Line ; Eye Proteins/genetics ; Eye Proteins/metabolism ; Female ; Gene Expression/genetics ; Gene Expression Regulation/genetics ; Gene Expression Regulation/physiology ; Genetic Vectors ; Male ; Mice ; Mice, Inbred C57BL ; Neovascularization, Pathologic/genetics ; Neovascularization, Pathologic/metabolism ; Neovascularization, Pathologic/physiopathology ; Nerve Growth Factors/genetics ; Nerve Growth Factors/metabolism ; Placenta Growth Factor/genetics ; Placenta Growth Factor/metabolism ; Retina/physiology ; Retinal Neovascularization/genetics ; Serpins/genetics ; Serpins/metabolism ; Vascular Endothelial Growth Factor A/genetics
Czasopismo naukowe
Tytuł :
Does ganciclovir exert retinal toxicity after multiple continuous intravitreal injections?
Autorzy :
Hu F; Beijing Institute of Ophthalmology, 17 Hougou Lane, Chongnei Street, Beijing, 100005, People's Republic of China.; Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, 17 Hougou Lane, Chongnei Street, Beijing, 100005, People's Republic of China.; Beijing Ophthalmology and Visual Science Key Laboratory, 17 Hougou Lane, Chongnei Street, Beijing, 100005, People's Republic of China.
Ma Y; Beijing Institute of Ophthalmology, 17 Hougou Lane, Chongnei Street, Beijing, 100005, People's Republic of China.; Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, 17 Hougou Lane, Chongnei Street, Beijing, 100005, People's Republic of China.; Beijing Ophthalmology and Visual Science Key Laboratory, 17 Hougou Lane, Chongnei Street, Beijing, 100005, People's Republic of China.
Peng X; Beijing Institute of Ophthalmology, 17 Hougou Lane, Chongnei Street, Beijing, 100005, People's Republic of China. .; Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, 17 Hougou Lane, Chongnei Street, Beijing, 100005, People's Republic of China. .; Beijing Ophthalmology and Visual Science Key Laboratory, 17 Hougou Lane, Chongnei Street, Beijing, 100005, People's Republic of China. .
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Źródło :
BMC infectious diseases [BMC Infect Dis] 2021 Jul 12; Vol. 21 (1), pp. 676. Date of Electronic Publication: 2021 Jul 12.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Ganciclovir/*adverse effects
Retina/*drug effects
Adult ; Dose-Response Relationship, Drug ; Electroretinography ; Female ; Ganciclovir/administration & dosage ; Ganciclovir/therapeutic use ; Humans ; Intravitreal Injections ; Photoreceptor Cells, Vertebrate/drug effects ; Retina/physiopathology ; Visual Acuity/drug effects
Czasopismo naukowe
Tytuł :
Optical Coherence Tomography Angiography in the Thirteen-Lined Ground Squirrel.
Autorzy :
Salmon AE; Cell Biology, Neurobiology, & Anatomy, Medical College of Wisconsin, Milwaukee, WI, USA.; Translational Imaging Innovations, Hickory, NC, USA.
Chen RC; Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, USA.
Atry F; Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, USA.
Gaffney M; Ophthalmology & Visual Sciences, Medical College of Wisconsin, Milwaukee, WI, USA.
Merriman DK; Biology, University of Wisconsin-Oshkosh, Oshkosh, WI, USA.
Gil DA; Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, USA.; Morgridge Institute for Research, Madison, WI, USA.
Skala MC; Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, USA.; Morgridge Institute for Research, Madison, WI, USA.
Collery R; Cell Biology, Neurobiology, & Anatomy, Medical College of Wisconsin, Milwaukee, WI, USA.; Ophthalmology & Visual Sciences, Medical College of Wisconsin, Milwaukee, WI, USA.
Allen KP; Microbiology & Immunology, Medical College of Wisconsin, Milwaukee, WI, USA.
Buckland E; Translational Imaging Innovations, Hickory, NC, USA.
Pashaie R; Computer & Electrical Engineering, Florida Atlantic University, Boca Raton, FL, USA.
Carroll J; Cell Biology, Neurobiology, & Anatomy, Medical College of Wisconsin, Milwaukee, WI, USA.; Ophthalmology & Visual Sciences, Medical College of Wisconsin, Milwaukee, WI, USA.; Biomedical Engineering, Marquette University, Milwaukee WI, USA.
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Źródło :
Translational vision science & technology [Transl Vis Sci Technol] 2021 Jul 01; Vol. 10 (8), pp. 5.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Retina*/diagnostic imaging
Tomography, Optical Coherence*
Angiography ; Animals ; Humans ; Ophthalmoscopy ; Sciuridae
Czasopismo naukowe
Tytuł :
Apical CLC-2 in retinal pigment epithelium is crucial for survival of the outer retina.
Autorzy :
Hanke-Gogokhia C; Department of Ophthalmology, Yale University, New Haven, CT, USA.
Lehmann GL; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA.
Benedicto I; Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.
de la Fuente-Ortega E; Departamento de Ciencias Biomédicas, Facultad de Medicina, Universidad Católica del Norte, Coquimbo, Chile.
Arshavsky VY; Department of Ophthalmology, Duke University School of Medicine, Durham, NC, USA.
Schreiner R; Division of Regenerative Medicine, Ansary Stem Cell Institute, Department of Medicine, Weill Cornell Medicine, New York, NY, USA.
Rodriguez-Boulan E; Department of Ophthalmology, Margaret Dyson Vision Research Institute, Weill Cornell Medicine, New York, NY, USA.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2021 Jul; Vol. 35 (7), pp. e21689.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Retinal Degeneration*
Chloride Channels/*physiology
Photoreceptor Cells/*cytology
Retina/*cytology
Retinal Pigment Epithelium/*metabolism
Animals ; Disease Models, Animal ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Photoreceptor Cells/metabolism ; Retina/metabolism
Czasopismo naukowe
Tytuł :
VEGF-R2/Caveolin-1 Pathway of Undifferentiated ARPE-19 Retina Cells: A Potential Target as Anti-VEGF-A Therapy in Wet AMD by Resvega, an Omega-3/Polyphenol Combination.
Autorzy :
Courtaut F; Université de Bourgogne Franche-Comté, 21000 Dijon, France.; INSERM Research Center U1231-Cancer and Adaptive Immune Response Team, Bioactive Molecules and Health Research Group, 21000 Dijon, France.
Scagliarini A; Université de Bourgogne Franche-Comté, 21000 Dijon, France.; INSERM Research Center U1231-Cancer and Adaptive Immune Response Team, Bioactive Molecules and Health Research Group, 21000 Dijon, France.
Aires V; Université de Bourgogne Franche-Comté, 21000 Dijon, France.; INSERM Research Center U1231-Cancer and Adaptive Immune Response Team, Bioactive Molecules and Health Research Group, 21000 Dijon, France.
Cornebise C; Université de Bourgogne Franche-Comté, 21000 Dijon, France.; INSERM Research Center U1231-Cancer and Adaptive Immune Response Team, Bioactive Molecules and Health Research Group, 21000 Dijon, France.
Pais de Barros JP; Université de Bourgogne Franche-Comté, 21000 Dijon, France.; INSERM Research Center U1231-Cancer and Adaptive Immune Response Team, Bioactive Molecules and Health Research Group, 21000 Dijon, France.; Lipidomic Analytical Platform, 21000 Dijon, France.
Olmiere C; Laboratoires Thea, 12 Rue Louis-Blériot, 63000 Clermont-Ferrand, France.
Delmas D; Université de Bourgogne Franche-Comté, 21000 Dijon, France.; INSERM Research Center U1231-Cancer and Adaptive Immune Response Team, Bioactive Molecules and Health Research Group, 21000 Dijon, France.; Centre Anticancéreux Georges François Leclerc Center, 21000 Dijon, France.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jun 19; Vol. 22 (12). Date of Electronic Publication: 2021 Jun 19.
Typ publikacji :
Journal Article
MeSH Terms :
Caveolin 1/*metabolism
Macular Degeneration/*prevention & control
Retina/*drug effects
Vascular Endothelial Growth Factor Receptor-2/*metabolism
Cell Line ; Drug Evaluation, Preclinical ; Humans ; MAP Kinase Signaling System/drug effects ; Retina/metabolism ; Transcription Factor AP-1/antagonists & inhibitors
Czasopismo naukowe
Tytuł :
Light-Modulated Sunscreen Mechanism in the Retina of the Human Eye.
Autorzy :
Luchowski R; Department of Biophysics, Institute of Physics, Maria Curie-Sklodowska University, Pl. M. Curie-Sklodowskiej 1, 20-031 Lublin, Poland.
Grudzinski W; Department of Biophysics, Institute of Physics, Maria Curie-Sklodowska University, Pl. M. Curie-Sklodowskiej 1, 20-031 Lublin, Poland.
Welc R; Department of Biophysics, Institute of Physics, Maria Curie-Sklodowska University, Pl. M. Curie-Sklodowskiej 1, 20-031 Lublin, Poland.
Mendes Pinto MM; Department of Biophysics, Institute of Physics, Maria Curie-Sklodowska University, Pl. M. Curie-Sklodowskiej 1, 20-031 Lublin, Poland.
Sek A; Department of Biophysics, Institute of Physics, Maria Curie-Sklodowska University, Pl. M. Curie-Sklodowskiej 1, 20-031 Lublin, Poland.; Department of Interfacial Phenomena, Institute of Chemical Sciences, Faculty of Chemistry, Maria Curie-Sklodowska University, Pl. M. Curie-Sklodowskiej 3, 20-031 Lublin, Poland.
Ostrowski J; Department of General Ophthalmology, Medical University of Lublin, Chmielna 1, 20-079 Lublin, Poland.
Nierzwicki L; Department of Physical Chemistry, Gdansk University of Technology, Narutowicza 11/12, 80-233 Gdansk, Poland.
Chodnicki P; Department of Physical Chemistry, Gdansk University of Technology, Narutowicza 11/12, 80-233 Gdansk, Poland.
Wieczor M; Department of Physical Chemistry, Gdansk University of Technology, Narutowicza 11/12, 80-233 Gdansk, Poland.
Sowinski K; Department of Biophysics, Institute of Physics, Maria Curie-Sklodowska University, Pl. M. Curie-Sklodowskiej 1, 20-031 Lublin, Poland.
Rejdak R; Department of General Ophthalmology, Medical University of Lublin, Chmielna 1, 20-079 Lublin, Poland.
Juenemann AGM; Viselle Augenzentrum Erlangen GmbH, 91052 Erlangen, Germany.
Teresinski G; Department of Forensic Medicine, Medical University of Lublin, Jaczewskiego 8b, 20-090 Lublin, Poland.
Czub J; Department of Physical Chemistry, Gdansk University of Technology, Narutowicza 11/12, 80-233 Gdansk, Poland.
Gruszecki WI; Department of Biophysics, Institute of Physics, Maria Curie-Sklodowska University, Pl. M. Curie-Sklodowskiej 1, 20-031 Lublin, Poland.
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Źródło :
The journal of physical chemistry. B [J Phys Chem B] 2021 Jun 17; Vol. 125 (23), pp. 6090-6102. Date of Electronic Publication: 2021 May 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Retina*
Sunscreening Agents*
Humans ; Lutein ; Spectrum Analysis, Raman ; Xanthophylls
Czasopismo naukowe
Tytuł :
Preservation of endoplasmic reticulum (ER) Ca stores by deletion of inositol-1,4,5-trisphosphate receptor type 1 promotes ER retrotranslocation, proteostasis, and protein outer segment localization in cyclic nucleotide-gated channel-deficient cone photoreceptors.
Autorzy :
Yang F; Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Ma H; Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Butler MR; Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Ding XQ; Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2021 Jun; Vol. 35 (6), pp. e21579.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Proteostasis*
Calcium/*metabolism
Cyclic Nucleotide-Gated Cation Channels/*deficiency
Endoplasmic Reticulum/*pathology
Inositol 1,4,5-Trisphosphate Receptors/*physiology
Retina/*pathology
Animals ; Endoplasmic Reticulum/metabolism ; Endoplasmic Reticulum Stress ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Protein Transport ; Retina/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
Montgomery and informed consent during Covid-19: Pneumatic retinopexy versus pars plana vitrectomy or scleral buckling for retinal detachment repair.
Autorzy :
Kiew G; Vitreoretinal Service, Addenbrooke's Hospital, Cambridge University NHS Foundation Trust, Cambridge, UK.
Poulson AV; Vitreoretinal Service, Addenbrooke's Hospital, Cambridge University NHS Foundation Trust, Cambridge, UK.
Newman DK; Vitreoretinal Service, Addenbrooke's Hospital, Cambridge University NHS Foundation Trust, Cambridge, UK.
Alexander P; Vitreoretinal Service, Addenbrooke's Hospital, Cambridge University NHS Foundation Trust, Cambridge, UK.
Snead MP; Vitreoretinal Service, Addenbrooke's Hospital, Cambridge University NHS Foundation Trust, Cambridge, UK.
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Źródło :
The Medico-legal journal [Med Leg J] 2021 Jun; Vol. 89 (2), pp. 102-105. Date of Electronic Publication: 2021 Mar 10.
Typ publikacji :
Journal Article
MeSH Terms :
Informed Consent/*standards
Retina/*surgery
Retinal Detachment/*surgery
Scleral Buckling/*standards
Vitrectomy/*standards
Aged ; COVID-19/prevention & control ; COVID-19/transmission ; Female ; Humans ; Informed Consent/legislation & jurisprudence ; Male ; Middle Aged ; Retina/physiopathology ; Retrospective Studies ; Scleral Buckling/statistics & numerical data ; Vitrectomy/statistics & numerical data
Czasopismo naukowe
Tytuł :
Retinal Features of Family Members With Familial Exudative Vitreoretinopathy Caused By Mutations in KIF11 Gene.
Autorzy :
Kondo H; Department of Ophthalmology, University of Occupational and Environmental Health, Kitakyushu, Japan.
Matsushita I; Department of Ophthalmology, University of Occupational and Environmental Health, Kitakyushu, Japan.
Nagata T; Department of Ophthalmology, University of Occupational and Environmental Health, Kitakyushu, Japan.
Fujihara E; Division of Ophthalmology, Matsue Red Cross Hospital, Matsue, Japan.
Hosono K; Department of Ophthalmology, Hamamatsu University School of Medicine, Shizuoka, Japan.
Uchio E; Department of Ophthalmology, Fukuoka University, Fukuoka, Japan.
Hotta Y; Department of Ophthalmology, Hamamatsu University School of Medicine, Shizuoka, Japan.
Kusaka S; Department of Ophthalmology, Kindai University Faculty of Medicine, Osakasayama, Japan.
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Źródło :
Translational vision science & technology [Transl Vis Sci Technol] 2021 Jun 01; Vol. 10 (7), pp. 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Kinesin*/genetics
Retina*
Familial Exudative Vitreoretinopathies/*genetics
Comparative Genomic Hybridization ; DNA Mutational Analysis ; Family ; Humans ; Mutation ; Pedigree
Czasopismo naukowe
Tytuł :
Multi-Modal Retinal Image Classification With Modality-Specific Attention Network.
Autorzy :
He X
Deng Y
Fang L
Peng Q
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Źródło :
IEEE transactions on medical imaging [IEEE Trans Med Imaging] 2021 Jun; Vol. 40 (6), pp. 1591-1602. Date of Electronic Publication: 2021 Jun 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Optic Disk*
Retina*/diagnostic imaging
Diagnostic Techniques, Ophthalmological ; Fundus Oculi ; Tomography, Optical Coherence
Czasopismo naukowe
Tytuł :
Severe acute respiratory Syndrome-Coronavirus-2: Can it be detected in the retina?
Autorzy :
Bayyoud T; Department of Ophthalmology, University Hospital Tübingen, Tübingen, Germany.
Iftner A; Institute for Medical Virology and Epidemiology of Viral Diseases, University Hospital Tübingen, Tübingen, Germany.
Iftner T; Institute for Medical Virology and Epidemiology of Viral Diseases, University Hospital Tübingen, Tübingen, Germany.
Bartz-Schmidt KU; Department of Ophthalmology, University Hospital Tübingen, Tübingen, Germany.
Ziemssen F; Department of Ophthalmology, University Hospital Tübingen, Tübingen, Germany.
Bösmüller H; Institute of Pathology and Neuropathology, University Hospital Tübingen, Tübingen, Germany.
Fend F; Institute of Pathology and Neuropathology, University Hospital Tübingen, Tübingen, Germany.
Rohrbach JM; Department of Ophthalmology, University Hospital Tübingen, Tübingen, Germany.
Ueffing M; Department of Ophthalmology, University Hospital Tübingen, Tübingen, Germany.; Institute for Ophthalmic Research, University of Tübingen, Tübingen, Germany.
Schindler M; Institute for Medical Virology and Epidemiology of Viral Diseases, University Hospital Tübingen, Tübingen, Germany.
Thaler S; Department of Ophthalmology, University Hospital Tübingen, Tübingen, Germany.
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Źródło :
PloS one [PLoS One] 2021 May 13; Vol. 16 (5), pp. e0251682. Date of Electronic Publication: 2021 May 13 (Print Publication: 2021).
Typ publikacji :
Journal Article
MeSH Terms :
COVID-19/*diagnosis
Retina/*virology
SARS-CoV-2/*isolation & purification
Autopsy ; COVID-19/pathology ; COVID-19 Nucleic Acid Testing ; Humans ; RNA, Viral/analysis ; Retina/pathology ; Vitreous Body/pathology ; Vitreous Body/virology
Czasopismo naukowe
Tytuł :
Longitudinal Evaluation of Hyper-Reflective Foci in the Retina Following Subretinal Delivery of Adeno-Associated Virus in Non-Human Primates.
Autorzy :
Rodríguez-Bocanegra E; University Eye Hospital, Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany.; Institute for Ophthalmic Research, Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany.
Wozar F; University Eye Hospital, Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany.; Institute for Ophthalmic Research, Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany.
Seitz IP; University Eye Hospital, Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany.; Institute for Ophthalmic Research, Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany.
Reichel FFL; University Eye Hospital, Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany.; Institute for Ophthalmic Research, Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany.
Ochakovski A; University Eye Hospital, Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany.; Institute for Ophthalmic Research, Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany.
Bucher K; University Eye Hospital, Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany.; Institute for Ophthalmic Research, Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany.
Wilhelm B; STZ Eye Trial at the Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany.
Bartz-Schmidt KU; University Eye Hospital, Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany.
Peters T; STZ Eye Trial at the Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany.
Fischer MD; University Eye Hospital, Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany.; Institute for Ophthalmic Research, Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany.; STZ Eye Trial at the Centre for Ophthalmology, University Hospital Tübingen, Tübingen, Germany.; Oxford Eye Hospital, Oxford University NHS Foundation Trust, Oxford, UK.; Nuffield Laboratory of Ophthalmology, Department of Clinical Neurosciences, University of Oxford, Oxford, UK.
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Corporate Authors :
RD-CURE Consortium
Źródło :
Translational vision science & technology [Transl Vis Sci Technol] 2021 May 03; Vol. 10 (6), pp. 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Dependovirus*/genetics
Retina*/diagnostic imaging
Animals ; Genetic Therapy ; Primates ; Tomography, Optical Coherence
Czasopismo naukowe

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