Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""RETINAL degeneration"" wg kryterium: Temat


Tytuł :
[Chorioretinal atrophy in pediatric cerebral folate deficiency-a preventable disease?]
Autorzy :
Kakkassery V; Klinik und Poliklinik für Augenheilkunde, Universitätsmedizin Rostock, Doberaner Str. 140, 18057, Rostock, Deutschland. .; Klinik für Augenheilkunde, Campus Lübeck, Universitätsklinikum Schleswig-Holstein, Lübeck, Deutschland. .
Koschmieder A; Klinik und Poliklinik für Augenheilkunde, Universitätsmedizin Rostock, Doberaner Str. 140, 18057, Rostock, Deutschland.
Walther F; Kinder- und Jugendklinik, Universitätsmedizin Rostock, Rostock, Deutschland.
Lehbrink R; Sektion Neuropädiatrie, Kinder- und Jugendklinik, Universitätsmedizin Rostock, Rostock, Deutschland.; Klinik für Kinder- und Jugendmedizin, Universitätsklinikum Münster, Münster, Deutschland.
Bertsche A; Sektion Neuropädiatrie, Kinder- und Jugendklinik, Universitätsmedizin Rostock, Rostock, Deutschland.
Wortmann SB; University Children's Hospital, Paracelsus Medical University (PMU), Salzburg, Österreich.; Institute of Human Genetics, Technical University München, München, Deutschland.; Radboud Center for Mitochondrial Medicine, Department of Pediatrics, Amalia Children's Hospital, Radboudumc, Nijmegen, Niederlande.
Buchmann J; Klinik für Psychiatrie, Neurologie, Psychosomatik und Psychotherapie im Kindes- und Jugendalter, Universitätsmedizin Rostock, Rostock, Deutschland.
Jäger M; Klinik und Poliklinik für Augenheilkunde, Justus-Liebig-Universität Gießen, Standort Gießen, Universitätsklinikum Gießen und Marburg GmbH, Gießen, Deutschland.
Friedburg C; Klinik und Poliklinik für Augenheilkunde, Justus-Liebig-Universität Gießen, Standort Gießen, Universitätsklinikum Gießen und Marburg GmbH, Gießen, Deutschland.
Lorenz B; Klinik und Poliklinik für Augenheilkunde, Justus-Liebig-Universität Gießen, Standort Gießen, Universitätsklinikum Gießen und Marburg GmbH, Gießen, Deutschland.
Jünemann A; Klinik und Poliklinik für Augenheilkunde, Universitätsmedizin Rostock, Doberaner Str. 140, 18057, Rostock, Deutschland.
Pokaż więcej
Transliterated Title :
Chorioretinale Atrophie bei kindlichem zerebralem Folatmangel – eine vermeidbare Erkrankung?
Źródło :
Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft [Ophthalmologe] 2021 Apr; Vol. 118 (4), pp. 383-390.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Folic Acid Deficiency*/diagnosis
Folic Acid Deficiency*/drug therapy
Folic Acid Deficiency*/genetics
Retinal Degeneration*
Adolescent ; Atrophy ; Child ; Child, Preschool ; Female ; Folate Receptor 1/genetics ; Folic Acid ; Humans
Czasopismo naukowe
Tytuł :
Clinical and Genetic Analysis of 63 Families Demonstrating Early and Advanced Characteristic Fundus as the Signature of CRB1 Mutations.
Autorzy :
Wang Y; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
Sun W; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
Xiao X; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
Li S; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
Jia X; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
Wang P; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
Zhang Q; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China. Electronic address: .
Pokaż więcej
Źródło :
American journal of ophthalmology [Am J Ophthalmol] 2021 Mar; Vol. 223, pp. 160-168. Date of Electronic Publication: 2020 Oct 24.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Eye Proteins/*genetics
Geographic Atrophy/*genetics
Membrane Proteins/*genetics
Mutation/*genetics
Nerve Tissue Proteins/*genetics
Retinal Degeneration/*genetics
Retinal Pigment Epithelium/*pathology
Adolescent ; Adult ; Child ; Child, Preschool ; DNA Mutational Analysis ; Electroretinography ; Family Health ; Female ; Fluorescein Angiography ; Fundus Oculi ; Genetic Association Studies ; Genetic Testing ; Geographic Atrophy/diagnosis ; Humans ; Infant ; Infant, Newborn ; Male ; Pedigree ; Retinal Degeneration/diagnosis ; Retrospective Studies ; Tomography, Optical Coherence ; Visual Acuity ; Whole Exome Sequencing
Czasopismo naukowe
Tytuł :
The functional characteristics of optogenetic gene therapy for vision restoration.
Autorzy :
Lindner M; The Nuffield Laboratory of Ophthalmology, Sleep and Circadian Neuroscience Institute, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK. .; Oxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK. .; Institute of Physiology and Pathophysiology, Department of Neurophysiology, Philipps University, Marburg, Germany. .
Gilhooley MJ; The Nuffield Laboratory of Ophthalmology, Sleep and Circadian Neuroscience Institute, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.; Oxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.; Department of Neuroophthalmology, Institute of Ophthalmology, London, UK.
Peirson SN; The Nuffield Laboratory of Ophthalmology, Sleep and Circadian Neuroscience Institute, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.
Hughes S; The Nuffield Laboratory of Ophthalmology, Sleep and Circadian Neuroscience Institute, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.
Hankins MW; The Nuffield Laboratory of Ophthalmology, Sleep and Circadian Neuroscience Institute, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK. .
Pokaż więcej
Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2021 Feb; Vol. 78 (4), pp. 1597-1613. Date of Electronic Publication: 2020 Jul 29.
Typ publikacji :
Journal Article
MeSH Terms :
Genetic Therapy*
Neurons/*metabolism
Retina/*metabolism
Retinal Degeneration/*therapy
Animals ; Channelrhodopsins/genetics ; Channelrhodopsins/therapeutic use ; Clinical Trials as Topic ; Gene Transfer Techniques/trends ; Genetic Vectors/therapeutic use ; Humans ; Light ; Mice ; Neurons/pathology ; Optogenetics ; Retina/pathology ; Retinal Degeneration/genetics ; Retinal Degeneration/pathology
Czasopismo naukowe
Tytuł :
Identification of Novel Substrates for cGMP Dependent Protein Kinase (PKG) through Kinase Activity Profiling to Understand Its Putative Role in Inherited Retinal Degeneration.
Autorzy :
Roy A; Division of Toxicology, Wageningen University and Research, Stippeneng 4, 6708 WE Wageningen, The Netherlands.; PamGene International B.V., P.O. Box 1345, 5200 BJ 's-Hertogenbosch, The Netherlands.
Groten J; Division of Toxicology, Wageningen University and Research, Stippeneng 4, 6708 WE Wageningen, The Netherlands.; PamGene International B.V., P.O. Box 1345, 5200 BJ 's-Hertogenbosch, The Netherlands.
Marigo V; Department of Life Sciences, University of Modena and Reggio Emilia, via Campi, 287, 41125 Modena, Italy.; Center for Neuroscience and Neurotechnology, University of Modena and Reggio Emilia, via Campi, 287, 41125 Modena, Italy.
Tomar T; PamGene International B.V., P.O. Box 1345, 5200 BJ 's-Hertogenbosch, The Netherlands.
Hilhorst R; PamGene International B.V., P.O. Box 1345, 5200 BJ 's-Hertogenbosch, The Netherlands.
Pokaż więcej
Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jan 25; Vol. 22 (3). Date of Electronic Publication: 2021 Jan 25.
Typ publikacji :
Journal Article
MeSH Terms :
Disease Susceptibility*
Carrier Proteins/*metabolism
Cyclic AMP-Dependent Protein Kinases/*metabolism
Retinal Degeneration/*etiology
Retinal Degeneration/*metabolism
Amino Acid Sequence ; Biomarkers ; Carrier Proteins/chemistry ; Cyclic AMP/metabolism ; Cyclic GMP/metabolism ; Enzyme Activation ; Genetic Predisposition to Disease ; Humans ; Kinetics ; Protein Binding ; Retinal Degeneration/pathology ; Substrate Specificity
Czasopismo naukowe
Tytuł :
Intravitreal ketamine promotes neuroprotection in rat eyes after experimental ischemia.
Autorzy :
Dourado LFN; Faculty of Pharmacy, Federal University of Minas Gerais, Pampulha, Av. Antônio Carlos, 6627, Belo Horizonte, Minas Gerais, 31270-901, Brazil. Electronic address: .
Oliveira LG; Faculty of Pharmacy, Federal University of Minas Gerais, Pampulha, Av. Antônio Carlos, 6627, Belo Horizonte, Minas Gerais, 31270-901, Brazil. Electronic address: .
da Silva CN; Faculty of Pharmacy, Federal University of Minas Gerais, Pampulha, Av. Antônio Carlos, 6627, Belo Horizonte, Minas Gerais, 31270-901, Brazil. Electronic address: .
Toledo CR; Faculty of Pharmacy, Federal University of Minas Gerais, Pampulha, Av. Antônio Carlos, 6627, Belo Horizonte, Minas Gerais, 31270-901, Brazil. Electronic address: .
Fialho SL; Pharmaceutical Research and Development, Ezequiel Dias Foundation, Rua Conde Pereira Carneiro, 80, Gameleira, Belo Horizonte, Minas Gerais, 30510-010, Brazil. Electronic address: .
Jorge R; Department of Ophthalmology, Otolaryngology and Head and Neck Surgery, Ribeirão Preto School of Medicine, Av. Bandeirantes, 3900, Ribeirão Preto, São Paulo, 14049-900, Brazil. Electronic address: .
Silva-Cunha A Júnior; Faculty of Pharmacy, Federal University of Minas Gerais, Pampulha, Av. Antônio Carlos, 6627, Belo Horizonte, Minas Gerais, 31270-901, Brazil. Electronic address: .
Pokaż więcej
Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 Jan; Vol. 133, pp. 110948. Date of Electronic Publication: 2020 Nov 26.
Typ publikacji :
Journal Article
MeSH Terms :
Excitatory Amino Acid Antagonists/*administration & dosage
Ischemia/*prevention & control
Ketamine/*administration & dosage
Neuroprotective Agents/*administration & dosage
Retinal Degeneration/*prevention & control
Retinal Neurons/*drug effects
Retinal Vessels/*drug effects
Animals ; Apoptosis/drug effects ; Cell Line ; Chick Embryo ; Disease Models, Animal ; Intravitreal Injections ; Ischemia/metabolism ; Ischemia/pathology ; Male ; Rats, Wistar ; Receptors, N-Methyl-D-Aspartate/antagonists & inhibitors ; Receptors, N-Methyl-D-Aspartate/metabolism ; Retinal Degeneration/metabolism ; Retinal Degeneration/pathology ; Retinal Neurons/metabolism ; Retinal Neurons/ultrastructure ; Retinal Vessels/metabolism ; Retinal Vessels/pathology
Czasopismo naukowe
Tytuł :
Optogenetic Strategies for Vision Restoration.
Autorzy :
Lu Q; Department of Ophthalmology, Visual and Anatomical Sciences, Wayne State University School of Medicine, Detroit, MI, USA.
Pan ZH; Department of Ophthalmology, Visual and Anatomical Sciences, Wayne State University School of Medicine, Detroit, MI, USA. .
Pokaż więcej
Źródło :
Advances in experimental medicine and biology [Adv Exp Med Biol] 2021; Vol. 1293, pp. 545-555.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Optogenetics*
Retinal Degeneration*/genetics
Retinal Degeneration*/therapy
Animals ; Channelrhodopsins ; Mice ; Retina ; Retinal Ganglion Cells ; Vision, Ocular
Czasopismo naukowe
Tytuł :
Metabolic Analysis of Vitreous/Lens and Retina in Wild Type and Retinal Degeneration Mice.
Autorzy :
Murenu E; Department of Ophthalmology, Ludwig-Maximilians-Universität München, Mathildenstraße 8, 80336 Munich, Germany.; Department of Pharmacy, Ludwig-Maximilians Universität München, Butenandtstr. 7, 81377 Munich, Germany.
Kostidis S; Leiden University Medical Center, Center for Proteomics & Metabolomics, P.O. Box 9600, 2300 RC Leiden, The Netherlands.
Lahiri S; Biomedical Center Munich-Molecular Biology, Ludwig-Maximilians-Universität München, Großhaderner Strasse 9, 82152 Planegg-Martinsried, Germany.
Geserich AS; Department of Pharmacy, Ludwig-Maximilians Universität München, Butenandtstr. 7, 81377 Munich, Germany.
Imhof A; Biomedical Center Munich-Molecular Biology, Ludwig-Maximilians-Universität München, Großhaderner Strasse 9, 82152 Planegg-Martinsried, Germany.
Giera M; Leiden University Medical Center, Center for Proteomics & Metabolomics, P.O. Box 9600, 2300 RC Leiden, The Netherlands.
Michalakis S; Department of Ophthalmology, Ludwig-Maximilians-Universität München, Mathildenstraße 8, 80336 Munich, Germany.; Department of Pharmacy, Ludwig-Maximilians Universität München, Butenandtstr. 7, 81377 Munich, Germany.
Pokaż więcej
Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Feb 26; Vol. 22 (5). Date of Electronic Publication: 2021 Feb 26.
Typ publikacji :
Journal Article
MeSH Terms :
Metabolome*
Lens, Crystalline/*metabolism
Retina/*metabolism
Retinal Degeneration/*metabolism
Vitreous Body/*metabolism
Animals ; Cyclic Nucleotide Phosphodiesterases, Type 6/genetics ; Disease Models, Animal ; Lens, Crystalline/pathology ; Mice ; Mutation ; Retina/pathology ; Retinal Degeneration/genetics ; Retinal Degeneration/pathology ; Vitreous Body/pathology
Czasopismo naukowe
Tytuł :
The Michigan Retinal Degeneration Questionnaire: A Patient-Reported Outcome Instrument for Inherited Retinal Degenerations.
Autorzy :
Lacy GD; Kellogg Eye Center, Department of Ophthalmology and Visual Sciences, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Abalem MF; Kellogg Eye Center, Department of Ophthalmology and Visual Sciences, University of Michigan Medical School, Ann Arbor, Michigan, USA; Department of Ophthalmology and Otolaryngology, University of Sao Paulo Medical School, São Paulo, Brazil.
Andrews CA; Kellogg Eye Center, Department of Ophthalmology and Visual Sciences, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Popova LT; Kellogg Eye Center, Department of Ophthalmology and Visual Sciences, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Santos EP; Kellogg Eye Center, Department of Ophthalmology and Visual Sciences, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Yu G; Kellogg Eye Center, Department of Ophthalmology and Visual Sciences, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Rakine HY; Kellogg Eye Center, Department of Ophthalmology and Visual Sciences, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Baig N; Kellogg Eye Center, Department of Ophthalmology and Visual Sciences, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Ehrlich JR; Kellogg Eye Center, Department of Ophthalmology and Visual Sciences, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Fahim AT; Kellogg Eye Center, Department of Ophthalmology and Visual Sciences, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Branham KH; Kellogg Eye Center, Department of Ophthalmology and Visual Sciences, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Stelmack JA; Department of Low Vision Service, Illinois Eye and Ear Infirmary, University of Illinois College of Medicine, Chicago, Illinois, USA.
Swenor BK; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Dagnelie G; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Musch DC; Kellogg Eye Center, Department of Ophthalmology and Visual Sciences, University of Michigan Medical School, Ann Arbor, Michigan, USA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA.
Jayasundera KT; Kellogg Eye Center, Department of Ophthalmology and Visual Sciences, University of Michigan Medical School, Ann Arbor, Michigan, USA. Electronic address: .
Pokaż więcej
Źródło :
American journal of ophthalmology [Am J Ophthalmol] 2021 Feb; Vol. 222, pp. 60-68. Date of Electronic Publication: 2020 Aug 26.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Patient Reported Outcome Measures*
Quality of Life*
Psychometrics/*methods
Retinal Degeneration/*diagnosis
Activities of Daily Living ; Adolescent ; Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Incidence ; Male ; Michigan/epidemiology ; Middle Aged ; Retinal Degeneration/epidemiology ; Retinal Degeneration/physiopathology ; Retrospective Studies ; Surveys and Questionnaires ; Young Adult
Czasopismo naukowe
Tytuł :
Automated segmentation and analysis of retinal microglia within ImageJ.
Autorzy :
Ash NF; University of Florida Department of Molecular Genetics and Microbiology, Box 100266 Gainesville, FL, 32610, USA.
Massengill MT; University of Florida Department of Molecular Genetics and Microbiology, Box 100266 Gainesville, FL, 32610, USA.
Harmer L; University of Florida Department of Molecular Genetics and Microbiology, Box 100266 Gainesville, FL, 32610, USA.
Jafri A; University of Florida Department of Molecular Genetics and Microbiology, Box 100266 Gainesville, FL, 32610, USA.
Lewin AS; University of Florida Department of Molecular Genetics and Microbiology, Box 100266 Gainesville, FL, 32610, USA. Electronic address: .
Pokaż więcej
Źródło :
Experimental eye research [Exp Eye Res] 2021 Feb; Vol. 203, pp. 108416. Date of Electronic Publication: 2020 Dec 24.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Image Processing, Computer-Assisted/*methods
Light/*adverse effects
Microglia/*pathology
Radiation Injuries, Experimental/*etiology
Retina/*radiation effects
Retinal Degeneration/*etiology
Algorithms ; Animals ; Cell Count ; Disease Models, Animal ; Imaging, Three-Dimensional ; Immunohistochemistry ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Radiation Injuries, Experimental/pathology ; Retinal Degeneration/pathology ; Retinal Vessels/pathology
Czasopismo naukowe
Tytuł :
Roots of Lithospermum erythrorhizon promotes retinal cell survival in optic nerve crush-induced retinal degeneration.
Autorzy :
Kang TK; Natural Product Research Center, Korea Institute of Science & Technology, Gangneung, 25451, Republic of Korea.
Le TT; Natural Product Research Center, Korea Institute of Science & Technology, Gangneung, 25451, Republic of Korea; Division of Bio-Medical Science & Technology, KIST School, Korea University of Science and Technology, Gangneung, 25451, Republic of Korea.
Kim KA; Division of Medical Oncology, Yonsei Cancer Center, Department of Internal Medicine, Yonsei University, Republic of Korea.
Kim YJ; Natural Product Research Center, Korea Institute of Science & Technology, Gangneung, 25451, Republic of Korea.
Lee WB; Natural Product Research Center, Korea Institute of Science & Technology, Gangneung, 25451, Republic of Korea. Electronic address: .
Jung SH; Natural Product Research Center, Korea Institute of Science & Technology, Gangneung, 25451, Republic of Korea; Division of Bio-Medical Science & Technology, KIST School, Korea University of Science and Technology, Gangneung, 25451, Republic of Korea. Electronic address: .
Pokaż więcej
Źródło :
Experimental eye research [Exp Eye Res] 2021 Feb; Vol. 203, pp. 108419. Date of Electronic Publication: 2020 Dec 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Lithospermum/*chemistry
Optic Nerve Injuries/*drug therapy
Phytotherapy/*methods
Plant Extracts/*therapeutic use
Plant Roots/*chemistry
Retinal Degeneration/*drug therapy
Retinal Ganglion Cells/*drug effects
Animals ; Apoptosis Regulatory Proteins/metabolism ; Benzofurans/pharmacology ; Cell Culture Techniques ; Cell Survival/drug effects ; Chromatography, High Pressure Liquid ; Depsides/pharmacology ; Electrophoresis, Polyacrylamide Gel ; Male ; Mice ; Mice, Inbred C57BL ; Nerve Crush ; Optic Nerve Injuries/metabolism ; Oxidative Stress/drug effects ; Reactive Oxygen Species/metabolism ; Retinal Degeneration/metabolism ; Retinal Ganglion Cells/metabolism ; Tomography, Optical Coherence
Czasopismo naukowe
Tytuł :
Reply to "Retinal INL Thickness in Multiple Sclerosis: A Mere Marker of Neurodegeneration?"
Autorzy :
Sotirchos ES; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD.
Calabresi PA; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD.
Saidha S; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD.
Pokaż więcej
Źródło :
Annals of neurology [Ann Neurol] 2021 Jan; Vol. 89 (1), pp. 193-194. Date of Electronic Publication: 2020 Oct 29.
Typ publikacji :
Letter; Comment
MeSH Terms :
Multiple Sclerosis*/diagnostic imaging
Multiple Sclerosis*/pathology
Multiple Sclerosis, Chronic Progressive*/pathology
Retinal Degeneration*/diagnostic imaging
Retinal Degeneration*/pathology
Atrophy/pathology ; Humans ; Retina/diagnostic imaging ; Retina/pathology
Opinia redakcyjna
Tytuł :
Retinal INL Thickness in Multiple Sclerosis: A Mere Marker of Neurodegeneration?
Autorzy :
Cordano C; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA.
Yiu HH; Department of Biology, University of Maryland, College Park, MD.
Oertel FC; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA.
Gelfand JM; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA.
Hauser SL; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA.
Cree BAC; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA.
Green AJ; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA.
Pokaż więcej
Corporate Authors :
University of California, San Francisco MS-EPIC Team; Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA.
Źródło :
Annals of neurology [Ann Neurol] 2021 Jan; Vol. 89 (1), pp. 192-193. Date of Electronic Publication: 2020 Nov 11.
Typ publikacji :
Letter; Comment
MeSH Terms :
Multiple Sclerosis*/diagnostic imaging
Multiple Sclerosis*/pathology
Multiple Sclerosis, Chronic Progressive*/pathology
Retinal Degeneration*/diagnostic imaging
Retinal Degeneration*/pathology
Atrophy/pathology ; Humans ; Retina/diagnostic imaging ; Retina/pathology
Opinia redakcyjna
Tytuł :
Functional assessment of cryopreserved clinical grade hESC-RPE cells as a qualified cell source for stem cell therapy of retinal degenerative diseases.
Autorzy :
Li QY; Southwest Hospital/ Southwest Eye Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, PR China; Key Lab of Visual Damage and Regeneration & Restoration of Chongqing, Chongqing, 400038, PR China.
Zou T; Southwest Hospital/ Southwest Eye Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, PR China; Key Lab of Visual Damage and Regeneration & Restoration of Chongqing, Chongqing, 400038, PR China.
Gong Y; Southwest Hospital/ Southwest Eye Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, PR China; Key Lab of Visual Damage and Regeneration & Restoration of Chongqing, Chongqing, 400038, PR China.
Chen SY; Southwest Hospital/ Southwest Eye Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, PR China; Key Lab of Visual Damage and Regeneration & Restoration of Chongqing, Chongqing, 400038, PR China.
Zeng YX; Southwest Hospital/ Southwest Eye Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, PR China; Key Lab of Visual Damage and Regeneration & Restoration of Chongqing, Chongqing, 400038, PR China.
Gao LX; Southwest Hospital/ Southwest Eye Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, PR China; Key Lab of Visual Damage and Regeneration & Restoration of Chongqing, Chongqing, 400038, PR China; Department of Ophthalmology, The 6th Medical Center of PLA General Hospital, Beijing, China.
Weng CH; Southwest Hospital/ Southwest Eye Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, PR China; Key Lab of Visual Damage and Regeneration & Restoration of Chongqing, Chongqing, 400038, PR China.
Xu HW; Southwest Hospital/ Southwest Eye Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, PR China; Key Lab of Visual Damage and Regeneration & Restoration of Chongqing, Chongqing, 400038, PR China. Electronic address: .
Yin ZQ; Southwest Hospital/ Southwest Eye Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, PR China; Key Lab of Visual Damage and Regeneration & Restoration of Chongqing, Chongqing, 400038, PR China. Electronic address: .
Pokaż więcej
Źródło :
Experimental eye research [Exp Eye Res] 2021 Jan; Vol. 202, pp. 108305. Date of Electronic Publication: 2020 Oct 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Stem Cell Transplantation*
Human Embryonic Stem Cells/*physiology
Retinal Degeneration/*therapy
Retinal Pigment Epithelium/*physiology
Cell Line ; Cell Polarity ; Cells, Cultured ; Cryopreservation ; Electric Impedance ; Human Embryonic Stem Cells/ultrastructure ; Humans ; Microscopy, Electron, Transmission ; Retinal Degeneration/metabolism ; Retinal Degeneration/physiopathology ; Retinal Pigment Epithelium/ultrastructure
Czasopismo naukowe
Tytuł :
Protective Effects of Flavonoids in Acute Models of Light-Induced Retinal Degeneration.
Autorzy :
Ortega JT; Department of Pharmacology, Cleveland Center for Membrane and Structural Biology, School of Medicine, Case Western Reserve University, Cleveland, Ohio.
Parmar T; Department of Pharmacology, Cleveland Center for Membrane and Structural Biology, School of Medicine, Case Western Reserve University, Cleveland, Ohio.
Golczak M; Department of Pharmacology, Cleveland Center for Membrane and Structural Biology, School of Medicine, Case Western Reserve University, Cleveland, Ohio.
Jastrzebska B; Department of Pharmacology, Cleveland Center for Membrane and Structural Biology, School of Medicine, Case Western Reserve University, Cleveland, Ohio .
Pokaż więcej
Źródło :
Molecular pharmacology [Mol Pharmacol] 2021 Jan; Vol. 99 (1), pp. 60-77. Date of Electronic Publication: 2020 Nov 05.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Flavonoids/*therapeutic use
Neuroprotective Agents/*therapeutic use
Photic Stimulation/*adverse effects
Retinal Degeneration/*pathology
Retinal Degeneration/*prevention & control
Animals ; Electroretinography/methods ; Female ; Male ; Mice ; Mice, 129 Strain ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Mice, Knockout ; Retinal Degeneration/etiology
Czasopismo naukowe
Tytuł :
Focused Update on AAV-Based Gene Therapy Clinical Trials for Inherited Retinal Degeneration.
Autorzy :
Fuller-Carter PI; Centre for Ophthalmology and Visual Sciences (Incorporating Lions Eye Institute), The University of Western Australia, Nedlands, WA, Australia.
Basiri H; Centre for Ophthalmology and Visual Sciences (Incorporating Lions Eye Institute), The University of Western Australia, Nedlands, WA, Australia.
Harvey AR; School of Human Sciences, The University of Western Australia, Crawley, WA, Australia.; Perron Institute for Neurological and Translational Science, Nedlands, WA, Australia.
Carvalho LS; Centre for Ophthalmology and Visual Sciences (Incorporating Lions Eye Institute), The University of Western Australia, Nedlands, WA, Australia. .
Pokaż więcej
Źródło :
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy [BioDrugs] 2020 Dec; Vol. 34 (6), pp. 763-781.
Typ publikacji :
Clinical Trial; Journal Article; Randomized Controlled Trial
MeSH Terms :
Leber Congenital Amaurosis*/genetics
Leber Congenital Amaurosis*/therapy
Retinal Degeneration*/genetics
Retinal Degeneration*/therapy
Dependovirus/*genetics
Genetic Therapy ; Genetic Vectors/genetics ; Humans
Czasopismo naukowe
Tytuł :
An Ophthalmic Rating Scale to Assess Ocular Involvement in Juvenile CLN3 Disease.
Autorzy :
Dulz S; Department of Ophthalmology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Electronic address: .
Atiskova Y; Department of Ophthalmology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Wibbeler E; Department of Pediatrics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Wildner J; Department of Ophthalmology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Wagenfeld L; Department of Ophthalmology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Schwering C; Department of Pediatrics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Nickel M; Department of Pediatrics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Bartsch U; Department of Ophthalmology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Spitzer MS; Department of Ophthalmology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Schulz A; Department of Pediatrics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Pokaż więcej
Źródło :
American journal of ophthalmology [Am J Ophthalmol] 2020 Dec; Vol. 220, pp. 64-71. Date of Electronic Publication: 2020 Jul 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mutation*
DNA/*genetics
Membrane Glycoproteins/*genetics
Molecular Chaperones/*genetics
Neuronal Ceroid-Lipofuscinoses/*complications
Retinal Degeneration/*etiology
Adolescent ; Child ; Child, Preschool ; Cross-Sectional Studies ; DNA Mutational Analysis ; Disease Progression ; Female ; Humans ; Male ; Membrane Glycoproteins/metabolism ; Molecular Chaperones/metabolism ; Neuronal Ceroid-Lipofuscinoses/diagnosis ; Neuronal Ceroid-Lipofuscinoses/genetics ; Retinal Degeneration/diagnosis ; Retinal Degeneration/genetics ; Retrospective Studies ; Tomography, Optical Coherence ; Young Adult
Czasopismo naukowe
Tytuł :
Metabolic Syndromes as Important Comorbidities in Patients of Inherited Retinal Degenerations: Experiences from the Nationwide Health Database and a Large Hospital-Based Cohort.
Autorzy :
Chiou GJ; Department of Medical Education, National Taiwan University Hospital, Taipei 100, Taiwan.
Huang DS; Department of Ophthalmology, National Taiwan University Hospital, Taipei 100, Taiwan.
Hu FR; Department of Ophthalmology, National Taiwan University Hospital, Taipei 100, Taiwan.; Department of Ophthalmology, College of Medicine, National Taiwan University, Taipei 100, Taiwan.
Yang CM; Department of Ophthalmology, National Taiwan University Hospital, Taipei 100, Taiwan.; Department of Ophthalmology, College of Medicine, National Taiwan University, Taipei 100, Taiwan.
Yang CH; Department of Ophthalmology, National Taiwan University Hospital, Taipei 100, Taiwan.; Department of Ophthalmology, College of Medicine, National Taiwan University, Taipei 100, Taiwan.
Huang CW; Department of Ophthalmology, National Taiwan University Hospital, Taipei 100, Taiwan.
Lin JW; Cardiovascular Center, National Taiwan University Hospital (Yun-Lin Branch), Yunlin 632, Taiwan.
Lin CW; Department of Ophthalmology, National Taiwan University Hospital, Taipei 100, Taiwan.
Ho TC; Department of Ophthalmology, National Taiwan University Hospital, Taipei 100, Taiwan.
Hsieh YT; Department of Ophthalmology, National Taiwan University Hospital, Taipei 100, Taiwan.
Lai TT; Department of Ophthalmology, National Taiwan University Hospital, Taipei 100, Taiwan.
Chen HM; Health Data Research Center, National Taiwan University, Taipei 100, Taiwan.
Chen PL; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei 100, Taiwan.; Graduate Institute of Medical Genomics and Proteomics, College of Medicine, National Taiwan University, Taipei 100, Taiwan.; Department of Medical Genetics, National Taiwan University Hospital, Taipei 100, Taiwan.
Hsiao CK; Institute of Epidemiology and Preventive Medicine, National Taiwan University, Taipei 100, Taiwan.
Chen TC; Department of Ophthalmology, National Taiwan University Hospital, Taipei 100, Taiwan.; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei 100, Taiwan.
Pokaż więcej
Źródło :
International journal of environmental research and public health [Int J Environ Res Public Health] 2021 Feb 20; Vol. 18 (4). Date of Electronic Publication: 2021 Feb 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Metabolic Syndrome*
Retinal Degeneration*
Cohort Studies ; Comorbidity ; Cross-Sectional Studies ; Hospitals ; Humans ; Retrospective Studies ; Taiwan/epidemiology
Czasopismo naukowe
Tytuł :
Author Response: Asymptomatic Optic Nerve Lesions: An Underestimated Cause of Silent Retinal Atrophy in MS.
Autorzy :
Outteryck O; (Lille, France).
Leclerc X; (Lille, France).
Pokaż więcej
Źródło :
Neurology [Neurology] 2021 Feb 16; Vol. 96 (7), pp. 350-351.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Optic Nerve*/diagnostic imaging
Optic Nerve*/pathology
Retinal Degeneration*/pathology
Atrophy/pathology ; Humans
Czasopismo naukowe
Tytuł :
[Neuroinflammation in neuronal ceroid lipofuscinosis].
Autorzy :
Behnke V; Lehrstuhl für Experimentelle Immunologie des Auges, Zentrum für Augenheilkunde, Medizinische Fakultät und Uniklinik Köln, Joseph-Stelzmann-Str. 9, 50931, Köln, Deutschland.
Langmann T; Lehrstuhl für Experimentelle Immunologie des Auges, Zentrum für Augenheilkunde, Medizinische Fakultät und Uniklinik Köln, Joseph-Stelzmann-Str. 9, 50931, Köln, Deutschland. .; Zentrum für Molekulare Medizin, Köln, Deutschland. .
Pokaż więcej
Transliterated Title :
Neuroinflammation bei neuronalen Ceroid-Lipofuszinosen.
Źródło :
Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft [Ophthalmologe] 2021 Feb; Vol. 118 (2), pp. 98-105. Date of Electronic Publication: 2021 Jan 07.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Neuronal Ceroid-Lipofuscinoses*/genetics
Retinal Degeneration*
Animals ; Central Nervous System ; Humans ; Retina
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies