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Tytuł :
ADAR1 Transcriptome editing promotes breast cancer progression through the regulation of cell cycle and DNA damage response.
Autorzy :
Sagredo EA; Center of Excellence in Precision Medicine, Pfizer Chile, Obispo Arturo Espinoza Campos 2526, CP 7810305 Santiago, Chile; Centro de Investigación y Tratamiento del Cáncer, Facultad de Medicina, Universidad de Chile, Independencia 1027, Santiago, Chile.
Sagredo AI; Center of Excellence in Precision Medicine, Pfizer Chile, Obispo Arturo Espinoza Campos 2526, CP 7810305 Santiago, Chile; Centro de Investigación y Tratamiento del Cáncer, Facultad de Medicina, Universidad de Chile, Independencia 1027, Santiago, Chile.
Blanco A; Center of Excellence in Precision Medicine, Pfizer Chile, Obispo Arturo Espinoza Campos 2526, CP 7810305 Santiago, Chile.
Rojas De Santiago P; Center of Excellence in Precision Medicine, Pfizer Chile, Obispo Arturo Espinoza Campos 2526, CP 7810305 Santiago, Chile.
Rivas S; Centro de Investigación y Tratamiento del Cáncer, Facultad de Medicina, Universidad de Chile, Independencia 1027, Santiago, Chile; Departamento de Oncología Básico Clínica, Facultad de Medicina, Universidad de Chile, Independencia 1027, Santiago, Chile.
Assar R; Center of Excellence in Precision Medicine, Pfizer Chile, Obispo Arturo Espinoza Campos 2526, CP 7810305 Santiago, Chile.
Pérez P; Center of Excellence in Precision Medicine, Pfizer Chile, Obispo Arturo Espinoza Campos 2526, CP 7810305 Santiago, Chile.
Marcelain K; Centro de Investigación y Tratamiento del Cáncer, Facultad de Medicina, Universidad de Chile, Independencia 1027, Santiago, Chile; Departamento de Oncología Básico Clínica, Facultad de Medicina, Universidad de Chile, Independencia 1027, Santiago, Chile. Electronic address: .
Armisén R; Center of Excellence in Precision Medicine, Pfizer Chile, Obispo Arturo Espinoza Campos 2526, CP 7810305 Santiago, Chile; Centro de Investigación y Tratamiento del Cáncer, Facultad de Medicina, Universidad de Chile, Independencia 1027, Santiago, Chile; Departamento de Oncología Básico Clínica, Facultad de Medicina, Universidad de Chile, Independencia 1027, Santiago, Chile; Centro de Genética y Genómica, Instituto de Ciencias e Innovación en Medicina, Facultad de Medicina Clínica Alemana Universidad del Desarrollo, Av. Las Condes 12461, Edificio 3, oficina 205, CP 7590943 Santiago, Chile. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Molecular cell research [Biochim Biophys Acta Mol Cell Res] 2020 Aug; Vol. 1867 (8), pp. 118716. Date of Electronic Publication: 2020 Apr 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731731 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-2596 (Electronic) Linking ISSN: 01674889 NLM ISO Abbreviation: Biochim Biophys Acta Mol Cell Res Subsets: MEDLINE
MeSH Terms :
RNA Editing*
Transcriptome*
Adenosine Deaminase/*metabolism
Breast Neoplasms/*metabolism
Cell Cycle/*physiology
DNA Damage/*physiology
RNA-Binding Proteins/*metabolism
Adenosine Deaminase/genetics ; Breast Neoplasms/genetics ; Breast Neoplasms/pathology ; Cell Line, Tumor ; Cell Proliferation ; Disease Progression ; Female ; Humans ; MCF-7 Cells ; RNA Stability ; RNA, Messenger/metabolism ; RNA-Binding Proteins/genetics
Czasopismo naukowe
Tytuł :
Intact RNA structurome reveals mRNA structure-mediated regulation of miRNA cleavage in vivo.
Autorzy :
Yang M; Department of Cell and Developmental Biology, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK.
Woolfenden HC; Department of Cell and Developmental Biology, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK.
Zhang Y; Department of Cell and Developmental Biology, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK.
Fang X; Department of Cell and Developmental Biology, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK.
Liu Q; Department of Cell and Developmental Biology, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK.
Vigh ML; Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, DK-2200, Copenhagen N, Denmark.
Cheema J; Department of Cell and Developmental Biology, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK.
Yang X; Department of Cell and Developmental Biology, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK.
Norris M; Department of Cell and Developmental Biology, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK.
Yu S; Department of Cell and Developmental Biology, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK.; National Key Laboratory of Plant Molecular Genetics (NKLPMG), CAS Center for Excellence in Molecular Plant Sciences, Institute of Plant Physiology and Ecology (SIPPE), Shanghai Institutes for Biological Sciences (SIBS), Shanghai 200032, People's Republic of China.
Carbonell A; Instituto de Biología Molecular y Celular de Plantas (Consejo Superior de Investigaciones Científicas-Universidad Politécnica de Valencia), Valencia, 46022, Spain.
Brodersen P; Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, DK-2200, Copenhagen N, Denmark.
Wang J; National Key Laboratory of Plant Molecular Genetics (NKLPMG), CAS Center for Excellence in Molecular Plant Sciences, Institute of Plant Physiology and Ecology (SIPPE), Shanghai Institutes for Biological Sciences (SIBS), Shanghai 200032, People's Republic of China.; ShanghaiTech University, Shanghai 200031, People's Republic of China.
Ding Y; Department of Cell and Developmental Biology, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2020 Sep 04; Vol. 48 (15), pp. 8767-8781.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE
MeSH Terms :
Nucleic Acid Conformation*
RNA Interference*
MicroRNAs/*ultrastructure
RNA/*ultrastructure
Arabidopsis/genetics ; Binding Sites/genetics ; MicroRNAs/genetics ; RNA/genetics ; RNA Recognition Motif Proteins/genetics ; RNA, Messenger/genetics ; RNA-Induced Silencing Complex/genetics
Czasopismo naukowe
Tytuł :
The SF3b complex: splicing and beyond.
Autorzy :
Sun C; Non-coding RNA and Drug Discovery Key Laboratory of Sichuan Province, Chengdu Medical College, Chengdu, 610500, China. .
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Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2020 Sep; Vol. 77 (18), pp. 3583-3595. Date of Electronic Publication: 2020 Mar 05.
Typ publikacji :
Journal Article; Review
Journal Info :
Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell. Mol. Life Sci. Subsets: MEDLINE
MeSH Terms :
RNA Splicing*
Multiprotein Complexes/*metabolism
RNA Splicing Factors/*metabolism
Humans ; Multiprotein Complexes/chemistry ; Neoplasms/metabolism ; Neoplasms/pathology ; Protein Structure, Quaternary ; RNA Precursors/metabolism ; RNA Splicing Factors/chemistry ; RNA, Messenger/metabolism ; Ribonucleoproteins, Small Nuclear/metabolism
Czasopismo naukowe
Tytuł :
Complete chemical structures of human mitochondrial tRNAs.
Autorzy :
Suzuki T; Department of Chemistry and Biotechnology, Graduate School of Engineering, University of Tokyo, Bunkyo-ku, Tokyo, 113-8656, Japan.
Yashiro Y; Department of Chemistry and Biotechnology, Graduate School of Engineering, University of Tokyo, Bunkyo-ku, Tokyo, 113-8656, Japan.
Kikuchi I; Department of Chemistry and Biotechnology, Graduate School of Engineering, University of Tokyo, Bunkyo-ku, Tokyo, 113-8656, Japan.
Ishigami Y; Department of Chemistry and Biotechnology, Graduate School of Engineering, University of Tokyo, Bunkyo-ku, Tokyo, 113-8656, Japan.
Saito H; RNA System Biochemistry Laboratory, Cluster for Pioneering Research, RIKEN, 2-1 Hirosawa, Wako, Saitama, 351-0198, Japan.; Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, University of Tokyo, Kashiwa, Chiba, 277-8562, Japan.
Matsuzawa I; Department of Chemistry and Biotechnology, Graduate School of Engineering, University of Tokyo, Bunkyo-ku, Tokyo, 113-8656, Japan.
Okada S; Department of Chemistry and Biotechnology, Graduate School of Engineering, University of Tokyo, Bunkyo-ku, Tokyo, 113-8656, Japan.; Research Institute for Biomedical Sciences, Tokyo University of Science, 2669 Yamazaki, Noda, Chiba, 278-0022, Japan.
Mito M; RNA System Biochemistry Laboratory, Cluster for Pioneering Research, RIKEN, 2-1 Hirosawa, Wako, Saitama, 351-0198, Japan.
Iwasaki S; RNA System Biochemistry Laboratory, Cluster for Pioneering Research, RIKEN, 2-1 Hirosawa, Wako, Saitama, 351-0198, Japan.; Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, University of Tokyo, Kashiwa, Chiba, 277-8562, Japan.
Ma D; Department of Chemistry and Biotechnology, Graduate School of Engineering, University of Tokyo, Bunkyo-ku, Tokyo, 113-8656, Japan.
Zhao X; Department of Chemistry and Biotechnology, Graduate School of Engineering, University of Tokyo, Bunkyo-ku, Tokyo, 113-8656, Japan.
Asano K; Department of Chemistry and Biotechnology, Graduate School of Engineering, University of Tokyo, Bunkyo-ku, Tokyo, 113-8656, Japan.
Lin H; Department of Chemistry and Biotechnology, Graduate School of Engineering, University of Tokyo, Bunkyo-ku, Tokyo, 113-8656, Japan.; State Key Laboratory of Marine Resource Utilization in South China Sea, Hainan University, 570228, Haikou, Hainan, P.R. China.
Kirino Y; Computational Medicine Center, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, 19107, USA.
Sakaguchi Y; Department of Chemistry and Biotechnology, Graduate School of Engineering, University of Tokyo, Bunkyo-ku, Tokyo, 113-8656, Japan.
Suzuki T; Department of Chemistry and Biotechnology, Graduate School of Engineering, University of Tokyo, Bunkyo-ku, Tokyo, 113-8656, Japan. .
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Źródło :
Nature communications [Nat Commun] 2020 Aug 28; Vol. 11 (1), pp. 4269. Date of Electronic Publication: 2020 Aug 28.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
MeSH Terms :
RNA Processing, Post-Transcriptional*
RNA, Mitochondrial/*chemistry
RNA, Transfer/*chemistry
Female ; Genetic Code ; HEK293 Cells ; HeLa Cells ; Humans ; Mass Spectrometry ; Mitochondria/metabolism ; Mitochondria/pathology ; Mitochondrial Diseases/genetics ; Mitochondrial Diseases/pathology ; Molecular Structure ; Nucleoside Q/biosynthesis ; Nucleoside Q/chemistry ; Oxidative Phosphorylation ; Placenta ; Pregnancy ; RNA, Mitochondrial/isolation & purification ; RNA, Mitochondrial/metabolism ; RNA, Transfer/isolation & purification ; RNA, Transfer/metabolism ; RNA-Seq
Czasopismo naukowe
Tytuł :
Lipids help double-stranded RNA in endosomal escape and improve RNA interference in the fall armyworm, Spodoptera frugiperda.
Autorzy :
Gurusamy D; Department of Entomology, University of Kentucky, Lexington, Kentucky, 40546, USA.
Mogilicherla K; Department of Entomology, University of Kentucky, Lexington, Kentucky, 40546, USA.
Shukla JN; Department of Entomology, University of Kentucky, Lexington, Kentucky, 40546, USA.
Palli SR; Department of Entomology, University of Kentucky, Lexington, Kentucky, 40546, USA.
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Źródło :
Archives of insect biochemistry and physiology [Arch Insect Biochem Physiol] 2020 Aug; Vol. 104 (4), pp. e21678. Date of Electronic Publication: 2020 Apr 15.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Wiley Country of Publication: United States NLM ID: 8501752 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6327 (Electronic) Linking ISSN: 07394462 NLM ISO Abbreviation: Arch. Insect Biochem. Physiol. Subsets: MEDLINE
MeSH Terms :
RNA Interference*
Liposomes/*administration & dosage
RNA, Double-Stranded/*administration & dosage
Spodoptera/*drug effects
Animals ; Endosomes ; Insect Control/methods ; Larva/drug effects ; RNA, Small Interfering ; Sf9 Cells ; Spodoptera/growth & development ; Transfection/methods
Czasopismo naukowe
Tytuł :
Transport of orally delivered dsRNA in southern green stink bug, Nezara viridula.
Autorzy :
Gurusamy D; Department of Entomology, University of Kentucky, Lexington, Kentucky.; Department of Botany, Kongunadu Arts and Science College, Bharathiar University, Coimbatore, Tamil Nadu, India.
Howell JL; Department of Entomology, University of Kentucky, Lexington, Kentucky.
Chereddy SCRR; Department of Entomology, University of Kentucky, Lexington, Kentucky.
Koo J; Department of Entomology, University of Kentucky, Lexington, Kentucky.
Palli SR; Department of Entomology, University of Kentucky, Lexington, Kentucky.
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Źródło :
Archives of insect biochemistry and physiology [Arch Insect Biochem Physiol] 2020 Aug; Vol. 104 (4), pp. e21692. Date of Electronic Publication: 2020 May 22.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Wiley Country of Publication: United States NLM ID: 8501752 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6327 (Electronic) Linking ISSN: 07394462 NLM ISO Abbreviation: Arch. Insect Biochem. Physiol. Subsets: MEDLINE
MeSH Terms :
RNA Interference*
Heteroptera/*metabolism
RNA, Double-Stranded/*metabolism
Administration, Oral ; Animals ; Heteroptera/genetics ; Injections ; Insect Control/methods ; Insect Proteins/genetics ; Intestinal Mucosa/metabolism ; RNA, Small Interfering
Czasopismo naukowe
Tytuł :
RNA interference-mediated control of cigarette beetle, Lasioderma serricorne.
Autorzy :
Koo J; Department of Entomology, College of Agriculture, University of Kentucky, Lexington, Kentucky.
Chereddy SCRR; Department of Entomology, College of Agriculture, University of Kentucky, Lexington, Kentucky.
Palli SR; Department of Entomology, College of Agriculture, University of Kentucky, Lexington, Kentucky.
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Źródło :
Archives of insect biochemistry and physiology [Arch Insect Biochem Physiol] 2020 Aug; Vol. 104 (4), pp. e21680. Date of Electronic Publication: 2020 Apr 28.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Wiley Country of Publication: United States NLM ID: 8501752 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6327 (Electronic) Linking ISSN: 07394462 NLM ISO Abbreviation: Arch. Insect Biochem. Physiol. Subsets: MEDLINE
MeSH Terms :
RNA Interference*
Coleoptera/*genetics
RNA, Double-Stranded/*genetics
Animals ; Coleoptera/growth & development ; Insect Proteins/genetics ; Larva/genetics ; RNA, Small Interfering ; Transcriptome
Czasopismo naukowe
Tytuł :
Gene Architecture and Sequence Composition Underpin Selective Dependency of Nuclear Export of Long RNAs on NXF1 and the TREX Complex.
Autorzy :
Zuckerman B; Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel.
Ron M; Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel.
Mikl M; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel; Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot 76100, Israel.
Segal E; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel; Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot 76100, Israel.
Ulitsky I; Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2020 Jul 16; Vol. 79 (2), pp. 251-267.e6. Date of Electronic Publication: 2020 Jun 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol. Cell Subsets: MEDLINE
MeSH Terms :
Active Transport, Cell Nucleus*
RNA Transport*
Multiprotein Complexes/*metabolism
Nucleocytoplasmic Transport Proteins/*physiology
RNA/*metabolism
RNA-Binding Proteins/*physiology
Animals ; Base Sequence ; Cell Line ; Cell Nucleus/metabolism ; Humans ; Mice ; RNA/chemistry ; RNA Stability ; RNA-Seq
Czasopismo naukowe
Tytuł :
BR-Bodies Provide Selectively Permeable Condensates that Stimulate mRNA Decay and Prevent Release of Decay Intermediates.
Autorzy :
Al-Husini N; Department of Biological Sciences, Wayne State University, Detroit, MI 48202, USA.
Tomares DT; Department of Chemistry, University of Pittsburgh, Pittsburgh, PA 15260, USA.
Pfaffenberger ZJ; Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA.
Muthunayake NS; Department of Biological Sciences, Wayne State University, Detroit, MI 48202, USA.
Samad MA; Department of Biological Sciences, Wayne State University, Detroit, MI 48202, USA.
Zuo T; Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA.
Bitar O; Department of Biological Sciences, Wayne State University, Detroit, MI 48202, USA.
Aretakis JR; Department of Biological Sciences, Wayne State University, Detroit, MI 48202, USA.
Bharmal MM; Department of Biological Sciences, Wayne State University, Detroit, MI 48202, USA.
Gega A; Department of Biological Sciences, Wayne State University, Detroit, MI 48202, USA.
Biteen JS; Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA.
Childers WS; Department of Chemistry, University of Pittsburgh, Pittsburgh, PA 15260, USA. Electronic address: .
Schrader JM; Department of Biological Sciences, Wayne State University, Detroit, MI 48202, USA. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2020 May 21; Vol. 78 (4), pp. 670-682.e8. Date of Electronic Publication: 2020 Apr 27.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol. Cell Subsets: MEDLINE
MeSH Terms :
RNA Stability*
Caulobacter crescentus/*metabolism
Endoribonucleases/*metabolism
Escherichia coli/*metabolism
Multienzyme Complexes/*metabolism
Organelles/*metabolism
Polyribonucleotide Nucleotidyltransferase/*metabolism
RNA Helicases/*metabolism
RNA, Messenger/*metabolism
Caulobacter crescentus/genetics ; Caulobacter crescentus/growth & development ; Endoribonucleases/genetics ; Escherichia coli/genetics ; Escherichia coli/growth & development ; Humans ; Multienzyme Complexes/genetics ; Organelles/genetics ; Polyribonucleotide Nucleotidyltransferase/genetics ; RNA Helicases/genetics ; RNA, Antisense/genetics ; RNA, Antisense/metabolism ; RNA, Messenger/genetics ; RNA, Ribosomal/genetics ; RNA, Ribosomal/metabolism ; RNA, Small Untranslated/genetics ; RNA, Small Untranslated/metabolism ; RNA, Transfer/genetics ; RNA, Transfer/metabolism ; RNA, Untranslated/genetics ; RNA, Untranslated/metabolism
Czasopismo naukowe
Tytuł :
Transcriptome-wide organization of subcellular microenvironments revealed by ATLAS-Seq.
Autorzy :
Adekunle DA; Department of Molecular Genetics & Microbiology, UF Genetics Institute, Center for NeuroGenetics, University of Florida, USA.; Department of Biology, Massachusetts Institute of Technology, USA.
Wang ET; Department of Molecular Genetics & Microbiology, UF Genetics Institute, Center for NeuroGenetics, University of Florida, USA.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2020 Jun 19; Vol. 48 (11), pp. 5859-5872.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
Journal Info :
Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res. Subsets: MEDLINE
MeSH Terms :
Cell Fractionation*
Cellular Microenvironment*
Sequence Analysis, RNA*
Transcriptome*
Intracellular Space/*chemistry
RNA/*analysis
RNA/*metabolism
Animals ; Cell Extracts/chemistry ; Centrifugation, Density Gradient ; Female ; Liver/cytology ; Liver/metabolism ; Mass Spectrometry ; Mice ; RNA/chemistry ; RNA-Binding Proteins/chemistry ; RNA-Binding Proteins/metabolism ; Ribosomes/chemistry ; Sucrose
Czasopismo naukowe
Tytuł :
Stability of RNA sequences derived from the coronavirus genome in human cells.
Autorzy :
Wakida H; Isotope Science Center, The University of Tokyo, 2-11-16 Yayoi, Bunkyo-ku, Tokyo, 113-0032, Japan; Department of Pharmaceutical Sciences, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo 113-0033, Japan.
Kawata K; Isotope Science Center, The University of Tokyo, 2-11-16 Yayoi, Bunkyo-ku, Tokyo, 113-0032, Japan.
Yamaji Y; Isotope Science Center, The University of Tokyo, 2-11-16 Yayoi, Bunkyo-ku, Tokyo, 113-0032, Japan; Department of Pharmaceutical Sciences, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo 113-0033, Japan.
Hattori E; Bioinformatics Laboratory, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan; Doctoral program in Biomedical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.
Tsuchiya T; Bioinformatics Laboratory, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan; Center for Artificial Intelligence Research, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8577, Japan.
Wada Y; Isotope Science Center, The University of Tokyo, 2-11-16 Yayoi, Bunkyo-ku, Tokyo, 113-0032, Japan.
Ozaki H; Bioinformatics Laboratory, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan; Center for Artificial Intelligence Research, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8577, Japan.
Akimitsu N; Isotope Science Center, The University of Tokyo, 2-11-16 Yayoi, Bunkyo-ku, Tokyo, 113-0032, Japan. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2020 Jul 05; Vol. 527 (4), pp. 993-999. Date of Electronic Publication: 2020 May 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem. Biophys. Res. Commun. Subsets: MEDLINE
MeSH Terms :
RNA Stability*
Betacoronavirus/*genetics
Coronavirus Infections/*virology
Pneumonia, Viral/*virology
RNA, Viral/*chemistry
SARS Virus/*genetics
Base Sequence ; Betacoronavirus/chemistry ; Conserved Sequence ; Coronaviridae/genetics ; Genome, Viral ; HeLa Cells ; Humans ; Nucleic Acid Conformation ; Pandemics ; SARS Virus/chemistry ; Sequence Analysis, RNA
SCR Disease Name :
COVID-19
SCR Organism :
severe acute respiratory syndrome coronavirus 2
Czasopismo naukowe
Tytuł :
DIS3L2 and LSm proteins are involved in the surveillance of Sm ring-deficient snRNAs.
Autorzy :
Roithová A; Laboratory of RNA Biology, Institute of Molecular Genetics of the Czech Academy of Sciences, Videnska 1083, 14220 Prague, Czech Republic.; Faculty of Science, Charles University, 128 00 Prague, Czech Republic.
Feketová Z; CEITEC-Central European Institute of Technology, Masaryk University, Kamenice 5/A35, 625 00 Brno, Czech Republic.
Vaňáčová Š; CEITEC-Central European Institute of Technology, Masaryk University, Kamenice 5/A35, 625 00 Brno, Czech Republic.
Staněk D; Laboratory of RNA Biology, Institute of Molecular Genetics of the Czech Academy of Sciences, Videnska 1083, 14220 Prague, Czech Republic.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2020 Jun 19; Vol. 48 (11), pp. 6184-6197.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res. Subsets: MEDLINE
MeSH Terms :
Nucleic Acid Conformation*
RNA Transport*
Exoribonucleases/*metabolism
Proto-Oncogene Proteins/*metabolism
RNA, Small Nuclear/*chemistry
RNA, Small Nuclear/*metabolism
RNA-Binding Proteins/*metabolism
Base Sequence ; Binding Sites ; HeLa Cells ; Humans ; Organelles/metabolism ; Protein Binding ; RNA Stability ; SMN Complex Proteins/metabolism
Czasopismo naukowe
Tytuł :
Prp5-Spt8/Spt3 interaction mediates a reciprocal coupling between splicing and transcription.
Autorzy :
Shao W; School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui 230032, China.; State Key Laboratory of Virology, Hubei Key Laboratory of Cell Homeostasis, College of Life Science, Wuhan University, Wuhan, Hubei 430072, China.
Ding Z; State Key Laboratory of Virology, Hubei Key Laboratory of Cell Homeostasis, College of Life Science, Wuhan University, Wuhan, Hubei 430072, China.; Key Laboratory of Insect Developmental and Evolutionary Biology, Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai 200032, China.
Zheng ZZ; Key Laboratory of Insect Developmental and Evolutionary Biology, Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai 200032, China.
Shen JJ; School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui 230032, China.
Shen YX; School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui 230032, China.
Pu J; Key Laboratory of Insect Developmental and Evolutionary Biology, Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai 200032, China.
Fan YJ; State Key Laboratory of Virology, Hubei Key Laboratory of Cell Homeostasis, College of Life Science, Wuhan University, Wuhan, Hubei 430072, China.
Query CC; Department of Cell Biology, Albert Einstein College of Medicine, NY 10461, USA.
Xu YZ; State Key Laboratory of Virology, Hubei Key Laboratory of Cell Homeostasis, College of Life Science, Wuhan University, Wuhan, Hubei 430072, China.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2020 Jun 19; Vol. 48 (11), pp. 5799-5813.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res. Subsets: MEDLINE
MeSH Terms :
RNA Splicing*
Transcription, Genetic*
DEAD-box RNA Helicases/*metabolism
Saccharomyces cerevisiae/*genetics
Saccharomyces cerevisiae/*metabolism
Saccharomyces cerevisiae Proteins/*metabolism
Transcription Factors/*metabolism
Alleles ; Genes, Fungal/genetics ; Genome, Fungal/genetics ; Mutation ; Phenotype ; Protein Binding ; RNA Polymerase II/metabolism ; Saccharomyces cerevisiae/growth & development ; Saccharomyces cerevisiae Proteins/genetics ; Substrate Specificity ; Transcription Factors/deficiency ; Transcription Factors/genetics
Czasopismo naukowe
Tytuł :
Regulation of mRNA export through API5 and nuclear FGF2 interaction.
Autorzy :
Bong SM; Research Institute, National Cancer Center, Goyang-si, Gyeonggi 10408, Republic of Korea.
Bae SH; Research Institute, National Cancer Center, Goyang-si, Gyeonggi 10408, Republic of Korea.; Department of Cancer Biomedical Science, National Cancer Center Graduate School of Cancer Science and Policy, Goyang-si, Gyeonggi 10408, Republic of Korea.
Song B; Research Institute, National Cancer Center, Goyang-si, Gyeonggi 10408, Republic of Korea.
Gwak H; Research Institute, National Cancer Center, Goyang-si, Gyeonggi 10408, Republic of Korea.
Yang SW; Research Institute, National Cancer Center, Goyang-si, Gyeonggi 10408, Republic of Korea.
Kim S; Research Institute, National Cancer Center, Goyang-si, Gyeonggi 10408, Republic of Korea.
Nam S; Department of Life Sciences, College of BioNano Technology and Department of Genome Medicine and Science, Graduate School of Medicine, Gachon University, Incheon 21565, Republic of Korea.
Rajalingam K; Cell Biology Unit, University Medical Center Mainz, JGU, Mainz, Germany.
Oh SJ; Department of Biomedical Sciences, Graduate School of Medicine, Korea University, Seoul 02841, Republic of Korea.
Kim TW; Department of Biomedical Sciences, Graduate School of Medicine, Korea University, Seoul 02841, Republic of Korea.
Park S; School of Systems Biomedical Science, Soongsil University, Seoul 06978, Republic of Korea.
Jang H; Research Institute, National Cancer Center, Goyang-si, Gyeonggi 10408, Republic of Korea.; Department of Cancer Biomedical Science, National Cancer Center Graduate School of Cancer Science and Policy, Goyang-si, Gyeonggi 10408, Republic of Korea.
Lee BI; Research Institute, National Cancer Center, Goyang-si, Gyeonggi 10408, Republic of Korea.; Department of Cancer Biomedical Science, National Cancer Center Graduate School of Cancer Science and Policy, Goyang-si, Gyeonggi 10408, Republic of Korea.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2020 Jun 19; Vol. 48 (11), pp. 6340-6352.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res. Subsets: MEDLINE
MeSH Terms :
RNA Transport*
Apoptosis Regulatory Proteins/*chemistry
Apoptosis Regulatory Proteins/*metabolism
Fibroblast Growth Factor 2/*chemistry
Fibroblast Growth Factor 2/*metabolism
Nuclear Proteins/*chemistry
Nuclear Proteins/*metabolism
RNA, Messenger/*metabolism
Active Transport, Cell Nucleus ; Cell Nucleus/metabolism ; Crystallography, X-Ray ; Cyclin D1/metabolism ; DEAD-box RNA Helicases/metabolism ; Eukaryotic Initiation Factor-4E/metabolism ; Humans ; Models, Molecular ; Neoplasm Proteins/metabolism ; Proto-Oncogene Proteins c-myc/metabolism
Czasopismo naukowe
Tytuł :
Asymmetric dimerization of adenosine deaminase acting on RNA facilitates substrate recognition.
Autorzy :
Thuy-Boun AS; Department of Chemistry, University of California, Davis, CA, USA.
Thomas JM; Department of Chemistry, University of California, Davis, CA, USA.
Grajo HL; Department of Chemistry, University of California, Davis, CA, USA.
Palumbo CM; Department of Chemistry, University of California, Davis, CA, USA.
Park S; Department of Chemistry, University of California, Davis, CA, USA.
Nguyen LT; Department of Chemistry, University of California, Davis, CA, USA.
Fisher AJ; Department of Chemistry, University of California, Davis, CA, USA.; Department of Molecular and Cellular Biology, University of California, Davis, CA, USA.
Beal PA; Department of Chemistry, University of California, Davis, CA, USA.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2020 Aug 20; Vol. 48 (14), pp. 7958-7972.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info :
Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res. Subsets: MEDLINE
MeSH Terms :
RNA Editing*
Adenosine Deaminase/*chemistry
Adenosine Deaminase/*metabolism
RNA, Double-Stranded/*metabolism
RNA-Binding Proteins/*chemistry
RNA-Binding Proteins/*metabolism
Adenosine Deaminase/genetics ; Crystallography, X-Ray ; Humans ; Models, Molecular ; Mutation ; Protein Binding ; Protein Domains ; Protein Multimerization ; RNA, Double-Stranded/chemistry ; RNA-Binding Proteins/genetics
Czasopismo naukowe
Tytuł :
Structure-Mediated RNA Decay by UPF1 and G3BP1.
Autorzy :
Fischer JW; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.
Busa VF; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.
Shao Y; Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.
Leung AKL; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA; Department of Molecular Biology and Genetics, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA; Department of Oncology, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2020 Apr 02; Vol. 78 (1), pp. 70-84.e6. Date of Electronic Publication: 2020 Feb 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol. Cell Subsets: MEDLINE
MeSH Terms :
3' Untranslated Regions*
RNA Stability*
DNA Helicases/*metabolism
Poly-ADP-Ribose Binding Proteins/*metabolism
RNA Helicases/*metabolism
RNA Recognition Motif Proteins/*metabolism
RNA, Messenger/*metabolism
Trans-Activators/*metabolism
Base Pairing ; Cell Line ; Gene Expression Regulation ; Humans ; RNA, Circular/chemistry ; RNA, Circular/metabolism
Czasopismo naukowe
Tytuł :
Splicing Kinetics and Coordination Revealed by Direct Nascent RNA Sequencing through Nanopores.
Autorzy :
Drexler HL; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
Choquet K; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
Churchman LS; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA. Electronic address: .
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Źródło :
Molecular cell [Mol Cell] 2020 Mar 05; Vol. 77 (5), pp. 985-998.e8. Date of Electronic Publication: 2019 Dec 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol. Cell Subsets: MEDLINE
MeSH Terms :
Nanopore Sequencing*
Nanopores*
RNA Splicing*
Transcriptome*
RNA Precursors/*metabolism
RNA, Messenger/*metabolism
Sequence Analysis, RNA/*methods
Animals ; Drosophila Proteins/genetics ; Drosophila Proteins/metabolism ; Drosophila melanogaster ; Humans ; Introns ; K562 Cells ; Kinetics ; RNA Polymerase II/genetics ; RNA Polymerase II/metabolism ; RNA Precursors/genetics ; RNA Splicing Factors/genetics ; RNA Splicing Factors/metabolism ; RNA, Messenger/genetics ; Transcription, Genetic
Czasopismo naukowe
Tytuł :
Role of SARS-CoV-2 in Altering the RNA-Binding Protein and miRNA-Directed Post-Transcriptional Regulatory Networks in Humans.
Autorzy :
Srivastava R; Department of Biohealth Informatics, School of Informatics and Computing, Indiana University Purdue University, 719 Indiana Ave Ste 319, Walker Plaza Building, Indianapolis, IN 46202, USA.
Daulatabad SV; Department of Biohealth Informatics, School of Informatics and Computing, Indiana University Purdue University, 719 Indiana Ave Ste 319, Walker Plaza Building, Indianapolis, IN 46202, USA.
Srivastava M; Department of Biohealth Informatics, School of Informatics and Computing, Indiana University Purdue University, 719 Indiana Ave Ste 319, Walker Plaza Building, Indianapolis, IN 46202, USA.
Janga SC; Department of Biohealth Informatics, School of Informatics and Computing, Indiana University Purdue University, 719 Indiana Ave Ste 319, Walker Plaza Building, Indianapolis, IN 46202, USA.; Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, 5021 Health Information and Translational Sciences (HITS), 410 West 10th Street, Indianapolis, IN 46202, USA.; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Medical Research and Library Building, 975 West Walnut Street, Indianapolis, IN 46202, USA.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Sep 25; Vol. 21 (19). Date of Electronic Publication: 2020 Sep 25.
Typ publikacji :
Journal Article
Journal Info :
Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE
MeSH Terms :
Gene Regulatory Networks*
RNA Processing, Post-Transcriptional*
Betacoronavirus/*genetics
Betacoronavirus/*metabolism
Coronavirus Infections/*virology
MicroRNAs/*genetics
Pneumonia, Viral/*virology
RNA-Binding Proteins/*metabolism
Gene Expression Regulation ; Genome, Viral ; Humans ; MicroRNAs/metabolism ; Pandemics ; Protein Interaction Maps ; RNA-Binding Proteins/genetics
SCR Disease Name :
COVID-19
SCR Organism :
severe acute respiratory syndrome coronavirus 2
Czasopismo naukowe
Tytuł :
SARS-CoV-2-encoded nucleocapsid protein acts as a viral suppressor of RNA interference in cells.
Autorzy :
Mu J; State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences (CAS), Wuhan, 430071, China.; Joint Laboratory of Infectious Diseases and Health, Wuhan Institute of Virology & Wuhan Jinyintan Hospital, CAS, Wuhan, 430023, China.
Xu J; State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences (CAS), Wuhan, 430071, China.; The University of Chinese Academy of Sciences, Beijing, 100049, China.
Zhang L; State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences (CAS), Wuhan, 430071, China.
Shu T; State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences (CAS), Wuhan, 430071, China.; Joint Laboratory of Infectious Diseases and Health, Wuhan Institute of Virology & Wuhan Jinyintan Hospital, CAS, Wuhan, 430023, China.; Center for Translational Medicine, Wuhan Jinyintan Hospital, Wuhan, 430040, China.
Wu D; State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences (CAS), Wuhan, 430071, China.; Joint Laboratory of Infectious Diseases and Health, Wuhan Institute of Virology & Wuhan Jinyintan Hospital, CAS, Wuhan, 430023, China.
Huang M; State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences (CAS), Wuhan, 430071, China.; Joint Laboratory of Infectious Diseases and Health, Wuhan Institute of Virology & Wuhan Jinyintan Hospital, CAS, Wuhan, 430023, China.
Ren Y; State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences (CAS), Wuhan, 430071, China.; Center for Precision Translational Medicine of Wuhan Institute of Virology and Guangzhou Women and Children's Medical Center, Guangzhou Women and Children's Medical Center, Guangzhou, 510120, China.
Li X; Center for Precision Translational Medicine of Wuhan Institute of Virology and Guangzhou Women and Children's Medical Center, Guangzhou Women and Children's Medical Center, Guangzhou, 510120, China.
Geng Q; Department of Thoracic Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Xu Y; Center for Precision Translational Medicine of Wuhan Institute of Virology and Guangzhou Women and Children's Medical Center, Guangzhou Women and Children's Medical Center, Guangzhou, 510120, China.
Qiu Y; State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences (CAS), Wuhan, 430071, China. .; Joint Laboratory of Infectious Diseases and Health, Wuhan Institute of Virology & Wuhan Jinyintan Hospital, CAS, Wuhan, 430023, China. .; The University of Chinese Academy of Sciences, Beijing, 100049, China. .
Zhou X; State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences (CAS), Wuhan, 430071, China. .; Joint Laboratory of Infectious Diseases and Health, Wuhan Institute of Virology & Wuhan Jinyintan Hospital, CAS, Wuhan, 430023, China. .; The University of Chinese Academy of Sciences, Beijing, 100049, China. .; Center for Translational Medicine, Wuhan Jinyintan Hospital, Wuhan, 430040, China. .
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Źródło :
Science China. Life sciences [Sci China Life Sci] 2020 Sep; Vol. 63 (9), pp. 1-4. Date of Electronic Publication: 2020 Apr 10.
Typ publikacji :
Letter; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Science China Press, co-published with Springer Country of Publication: China NLM ID: 101529880 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1869-1889 (Electronic) Linking ISSN: 16747305 NLM ISO Abbreviation: Sci China Life Sci Subsets: MEDLINE
MeSH Terms :
RNA Interference*
Betacoronavirus/*genetics
Coronavirus Infections/*genetics
Coronavirus Infections/*virology
Nucleocapsid Proteins/*genetics
Pneumonia, Viral/*genetics
Pneumonia, Viral/*virology
Betacoronavirus/pathogenicity ; Betacoronavirus/physiology ; DEAD-box RNA Helicases/metabolism ; Green Fluorescent Proteins/antagonists & inhibitors ; Green Fluorescent Proteins/genetics ; HEK293 Cells ; Humans ; Nucleocapsid Proteins/physiology ; Pandemics ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; RNA, Small Interfering/genetics ; RNA-Binding Proteins/genetics ; RNA-Binding Proteins/physiology ; Ribonuclease III/metabolism ; Transfection
SCR Disease Name :
COVID-19
SCR Organism :
severe acute respiratory syndrome coronavirus 2
Raport
Tytuł :
Hypomodified tRNA in evolutionarily distant yeasts can trigger rapid tRNA decay to activate the general amino acid control response, but with different consequences.
Autorzy :
De Zoysa T; Department of Biochemistry and Biophysics, Center for RNA Biology, University of Rochester School of Medicine, Rochester, NY, United States of America.
Phizicky EM; Department of Biochemistry and Biophysics, Center for RNA Biology, University of Rochester School of Medicine, Rochester, NY, United States of America.
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Źródło :
PLoS genetics [PLoS Genet] 2020 Aug 25; Vol. 16 (8), pp. e1008893. Date of Electronic Publication: 2020 Aug 25 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
Journal Info :
Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet. Subsets: MEDLINE
MeSH Terms :
RNA Processing, Post-Transcriptional*
RNA Stability*
Exoribonucleases/*metabolism
RNA, Transfer/*genetics
Schizosaccharomyces pombe Proteins/*metabolism
tRNA Methyltransferases/*metabolism
Amino Acids/metabolism ; Evolution, Molecular ; Exoribonucleases/genetics ; RNA, Transfer/metabolism ; Schizosaccharomyces ; Schizosaccharomyces pombe Proteins/genetics ; tRNA Methyltransferases/genetics
Czasopismo naukowe

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