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Tytuł:
Maternal mRNA deadenylation and allocation via Rbm14 condensates facilitate vertebrate blastula development.
Autorzy:
Xiao Y; Key Laboratory of Systems Health Science of Zhejiang Province, School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, China.
Chen J; State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, China.
Yang S; State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, China.
Sun H; State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, China.
Xie L; State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, China.
Li J; State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, China.
Jing N; State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, China.; Bioland Laboratory (Guangzhou Regenerative Medicine and Health Guangdong Laboratory), Guangzhou, China.
Zhu X; Key Laboratory of Systems Health Science of Zhejiang Province, School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, China.; State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai, China.
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Źródło:
The EMBO journal [EMBO J] 2023 Feb 01; Vol. 42 (3), pp. e111364. Date of Electronic Publication: 2022 Dec 07.
Typ publikacji:
Journal Article
MeSH Terms:
RNA, Messenger, Stored*/genetics
RNA, Messenger, Stored*/metabolism
Zebrafish*
Pregnancy ; Female ; Animals ; Mice ; Blastula/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Blastocyst/metabolism ; Embryonic Development/genetics ; Gene Expression Regulation, Developmental
Czasopismo naukowe
Szczegóły
Tytuł:
Developmental mRNA m C modification of maternal mRNAs in animals.
Autorzy:
Liu J; MOE Key Laboratory of Gene Function and Regulation, Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, PR China.
Huang T; MOE Key Laboratory of Gene Function and Regulation, Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, PR China.
Chen W; MOE Key Laboratory of Gene Function and Regulation, Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, PR China.
Ding C; Guangdong Provincial Key Laboratory of Reproductive Medicine, Center for Reproductive Medicine and Department of Gynecology & Obstetrics, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, PR China.
Zhao T; MOE Key Laboratory of Gene Function and Regulation, Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, PR China.
Zhao X; MOE Key Laboratory of Gene Function and Regulation, Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, PR China.
Cai B; Guangdong Provincial Key Laboratory of Reproductive Medicine, Center for Reproductive Medicine and Department of Gynecology & Obstetrics, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, PR China.
Zhang Y; MOE Key Laboratory of Gene Function and Regulation, Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, PR China.
Li S; Guangdong Provincial Key Laboratory of Reproductive Medicine, Center for Reproductive Medicine and Department of Gynecology & Obstetrics, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, PR China.
Zhang L; MOE Key Laboratory of Gene Function and Regulation, Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, PR China.
Xue M; Division of Human Reproduction and Developmental Genetics, Zhejiang Provincial Key Laboratory of Precision Diagnosis and Therapy for Major Gynecological Diseases, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310006, China.; Institute of Genetics, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310058, China.
He X; MOE Key Laboratory of Gene Function and Regulation, Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, PR China.
Ge W; Division of Human Reproduction and Developmental Genetics, Zhejiang Provincial Key Laboratory of Precision Diagnosis and Therapy for Major Gynecological Diseases, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310006, China. .; Institute of Genetics, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310058, China. .; Cancer Center, Zhejiang University, Hangzhou, Zhejiang, 310058, China. .
Zhou C; Guangdong Provincial Key Laboratory of Reproductive Medicine, Center for Reproductive Medicine and Department of Gynecology & Obstetrics, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, PR China. .
Xu Y; Guangdong Provincial Key Laboratory of Reproductive Medicine, Center for Reproductive Medicine and Department of Gynecology & Obstetrics, the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, PR China. .
Zhang R; MOE Key Laboratory of Gene Function and Regulation, Guangdong Province Key Laboratory of Pharmaceutical Functional Genes, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, PR China. .
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Źródło:
Nature communications [Nat Commun] 2022 May 05; Vol. 13 (1), pp. 2484. Date of Electronic Publication: 2022 May 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
RNA, Messenger, Stored*/genetics
RNA, Messenger, Stored*/metabolism
Zygote*/metabolism
Animals ; Drosophila/genetics ; Embryonic Development/genetics ; Gene Expression Regulation, Developmental ; Methylation ; RNA, Messenger/genetics ; RNA, Messenger/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Dynamic changes in the association between maternal mRNAs and endoplasmic reticulum during ascidian early embryogenesis.
Autorzy:
Goto T; Frontiers of Innovative Research in Science and Technology (FIRST), Konan University, 7-1-20 Minatojima-minamimachi, Chuo-ku, Kobe, Hyogo, 650-0047, Japan.; Laboratory for Cellular Function Imaging, RIKEN Center for Biosystems Dynamics Research, Kobe, Hyogo, 650-0047, Japan.
Torii S; Frontiers of Innovative Research in Science and Technology (FIRST), Konan University, 7-1-20 Minatojima-minamimachi, Chuo-ku, Kobe, Hyogo, 650-0047, Japan.
Kondo A; Frontiers of Innovative Research in Science and Technology (FIRST), Konan University, 7-1-20 Minatojima-minamimachi, Chuo-ku, Kobe, Hyogo, 650-0047, Japan.
Kawakami J; Frontiers of Innovative Research in Science and Technology (FIRST), Konan University, 7-1-20 Minatojima-minamimachi, Chuo-ku, Kobe, Hyogo, 650-0047, Japan.
Yagi H; Japan Testing Laboratories, Inc, Kobe, Hyogo, 654-0161, Japan.
Suekane M; Japan Testing Laboratories, Inc, Kobe, Hyogo, 654-0161, Japan.
Kataoka Y; Laboratory for Cellular Function Imaging, RIKEN Center for Biosystems Dynamics Research, Kobe, Hyogo, 650-0047, Japan.; Multi-Modal Microstructure Analysis Unit, RIKEN-JEOL Collaboration Center, Kobe, Hyogo, 650-0047, Japan.
Nishikata T; Frontiers of Innovative Research in Science and Technology (FIRST), Konan University, 7-1-20 Minatojima-minamimachi, Chuo-ku, Kobe, Hyogo, 650-0047, Japan. .
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Źródło:
Development genes and evolution [Dev Genes Evol] 2022 Feb; Vol. 232 (1), pp. 1-14. Date of Electronic Publication: 2021 Dec 18.
Typ publikacji:
Journal Article
MeSH Terms:
RNA, Messenger, Stored*/genetics
Urochordata*/genetics
Animals ; Embryonic Development/genetics ; Endoplasmic Reticulum ; Oocytes ; RNA, Messenger/genetics
Czasopismo naukowe
Szczegóły
Tytuł:
Expression Profiles of Long Noncoding RNAs and Messenger RNAs in a Rat Model of Spinal Cord Injury.
Autorzy:
Cao J; Department of Orthopedics, The Second Affiliated Hospital of Nanchang University, 330006, 1 Minde Road, East Laker District, Nanchang, China.
Tang T; Institute of Orthopedics of Jiangxi Province, Jiangxi 330006, 1 Minde Road, East Laker District, Nanchang, China.
Tan J; Institute of Minimally Invasive Orthopedics, Nanchang University, Jiangxi 330006, 1 Minde Road, East Laker District, Nanchang, China.
Chen Q; Jiangxi Key Laboratory of Intervertebral Disc Disease, Nanchang University, Jiangxi 330006, 1 Minde Road, East Laker District, Nanchang, China.
Yuan J; Institute of Orthopedics of Jiangxi Province, Jiangxi 330006, 1 Minde Road, East Laker District, Nanchang, China.
Li T; Institute of Minimally Invasive Orthopedics, Nanchang University, Jiangxi 330006, 1 Minde Road, East Laker District, Nanchang, China.
Cheng X; Department of Orthopedics, The Second Affiliated Hospital of Nanchang University, 330006, 1 Minde Road, East Laker District, Nanchang, China.; Institute of Orthopedics of Jiangxi Province, Jiangxi 330006, 1 Minde Road, East Laker District, Nanchang, China.; Institute of Minimally Invasive Orthopedics, Nanchang University, Jiangxi 330006, 1 Minde Road, East Laker District, Nanchang, China.; Jiangxi Key Laboratory of Intervertebral Disc Disease, Nanchang University, Jiangxi 330006, 1 Minde Road, East Laker District, Nanchang, China.
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Źródło:
Computational and mathematical methods in medicine [Comput Math Methods Med] 2023 Jan 19; Vol. 2023, pp. 6033020. Date of Electronic Publication: 2023 Jan 19 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
RNA, Long Noncoding*/genetics
RNA, Long Noncoding*/metabolism
RNA, Messenger*/genetics
RNA, Messenger*/metabolism
Spinal Cord Injuries*/genetics
Spinal Cord Injuries*/metabolism
Animals ; Rats ; Gene Expression Profiling ; Gene Regulatory Networks ; Inflammation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
UTRdb 2.0: a comprehensive, expert curated catalog of eukaryotic mRNAs untranslated regions.
Autorzy:
Lo Giudice C; Department of Biosciences, Biotechnology and Environment, University of Bari A. Moro, 70126 Bari, Italy.
Zambelli F; Department of Biosciences, University of Milan, 20133 Milan, Italy.; Institute of Biomembranes, Bioenergetics and Molecular Biotechnology, Consiglio Nazionale delle Ricerche, 70126 Bari, Italy.
Chiara M; Department of Biosciences, University of Milan, 20133 Milan, Italy.; Institute of Biomembranes, Bioenergetics and Molecular Biotechnology, Consiglio Nazionale delle Ricerche, 70126 Bari, Italy.
Pavesi G; Department of Biosciences, University of Milan, 20133 Milan, Italy.; Institute of Biomembranes, Bioenergetics and Molecular Biotechnology, Consiglio Nazionale delle Ricerche, 70126 Bari, Italy.
Tangaro MA; Institute of Biomembranes, Bioenergetics and Molecular Biotechnology, Consiglio Nazionale delle Ricerche, 70126 Bari, Italy.
Picardi E; Department of Biosciences, Biotechnology and Environment, University of Bari A. Moro, 70126 Bari, Italy.; Institute of Biomembranes, Bioenergetics and Molecular Biotechnology, Consiglio Nazionale delle Ricerche, 70126 Bari, Italy.
Pesole G; Department of Biosciences, Biotechnology and Environment, University of Bari A. Moro, 70126 Bari, Italy.; Institute of Biomembranes, Bioenergetics and Molecular Biotechnology, Consiglio Nazionale delle Ricerche, 70126 Bari, Italy.
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2023 Jan 06; Vol. 51 (D1), pp. D337-D344.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Eukaryota*/genetics
RNA, Messenger*/genetics
RNA, Messenger*/metabolism
Untranslated Regions*
Databases, Nucleic Acid*
3' Untranslated Regions/genetics ; 5' Untranslated Regions ; Eukaryotic Cells/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Modulation of gene expression by YTH domain family (YTHDF) proteins in human physiology and pathology.
Autorzy:
Kisan A; Department of Biochemistry, School of Basic Sciences, Central University of Punjab, Bathinda, Punjab, India.
Chhabra R; Department of Biochemistry, School of Basic Sciences, Central University of Punjab, Bathinda, Punjab, India.
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Źródło:
Journal of cellular physiology [J Cell Physiol] 2023 Jan; Vol. 238 (1), pp. 5-31. Date of Electronic Publication: 2022 Nov 03.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
RNA, Messenger*/genetics
RNA, Messenger*/metabolism
RNA-Binding Proteins*/genetics
RNA-Binding Proteins*/metabolism
Humans ; Gene Expression ; Methylation
Czasopismo naukowe
Szczegóły
Tytuł:
Trial settles debate over best design for mRNA in COVID vaccines.
Autorzy:
Dolgin E
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Źródło:
Nature [Nature] 2023 Jan; Vol. 613 (7944), pp. 419-420.
Typ publikacji:
Wiadomości
MeSH Terms:
COVID-19*/prevention & control
COVID-19 Vaccines*/chemistry
COVID-19 Vaccines*/genetics
RNA, Messenger*/chemistry
RNA, Messenger*/genetics
mRNA Vaccines*/chemistry
mRNA Vaccines*/genetics
Vaccine Development*/standards
Drug Design*/standards
Clinical Trials as Topic*
Humans
Periodyk
Szczegóły
Tytuł:
CRC-derived exosomes containing the RNA binding protein HuR promote lung cell proliferation by stabilizing c-Myc mRNA.
Autorzy:
Xiao H; Department of Respiratory and Critical Care Medicine, Shanghai General Hospital, Shanghai Jiaotong University, Shanghai, China.; Department of Molecular Biosciences, University of Kansas Cancer Center, University of Kansas, Lawrence, Kansas, USA.
Ye X; College of Clinical Medicine, Shanghai University of Medicine & Health Science, Shanghai, China.
Vishwakarma V; Department of Molecular Biosciences, University of Kansas Cancer Center, University of Kansas, Lawrence, Kansas, USA.
Preet R; Department of Molecular Biosciences, University of Kansas Cancer Center, University of Kansas, Lawrence, Kansas, USA.
Dixon DA; Department of Molecular Biosciences, University of Kansas Cancer Center, University of Kansas, Lawrence, Kansas, USA.
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Źródło:
Cancer biology & therapy [Cancer Biol Ther] 2022 Dec 31; Vol. 23 (1), pp. 139-149.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Colonic Neoplasms*/genetics
Colonic Neoplasms*/metabolism
Colonic Neoplasms*/pathology
ELAV-Like Protein 1*/genetics
Exosomes*/genetics
Exosomes*/metabolism
Lung Neoplasms*/genetics
Lung Neoplasms*/metabolism
MicroRNAs*/genetics
MicroRNAs*/metabolism
Proto-Oncogene Proteins c-myc*/genetics
Proto-Oncogene Proteins c-myc*/metabolism
RNA, Messenger*/genetics
RNA, Messenger*/metabolism
Cell Line, Tumor ; Cell Proliferation ; HCT116 Cells ; Humans ; Lung/pathology ; RNA-Binding Proteins/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Construction and function analysis of the LncRNA-miRNA-mRNA competing endogenous RNA network in autoimmune hepatitis.
Autorzy:
Li Z; College of Basic Medical Sciences, Shanxi University of Chinese Medicine, Jinzhong, 030619, People's Republic of China. .; Basic Laboratory of Integrated Traditional Chinese and Western Medicine, Shanxi University of Chinese Medicine, Jinzhong, 030619, People's Republic of China. .
Liu Y; College of Basic Medical Sciences, Shanxi University of Chinese Medicine, Jinzhong, 030619, People's Republic of China.; Basic Laboratory of Integrated Traditional Chinese and Western Medicine, Shanxi University of Chinese Medicine, Jinzhong, 030619, People's Republic of China.
Hou Y; College of Basic Medical Sciences, Shanxi University of Chinese Medicine, Jinzhong, 030619, People's Republic of China.; Basic Laboratory of Integrated Traditional Chinese and Western Medicine, Shanxi University of Chinese Medicine, Jinzhong, 030619, People's Republic of China.
Li Z; College of Basic Medical Sciences, Shanxi University of Chinese Medicine, Jinzhong, 030619, People's Republic of China.; Basic Laboratory of Integrated Traditional Chinese and Western Medicine, Shanxi University of Chinese Medicine, Jinzhong, 030619, People's Republic of China.
Chen C; College of Basic Medical Sciences, Shanxi University of Chinese Medicine, Jinzhong, 030619, People's Republic of China.; Basic Laboratory of Integrated Traditional Chinese and Western Medicine, Shanxi University of Chinese Medicine, Jinzhong, 030619, People's Republic of China.
Hao H; College of Basic Medical Sciences, Shanxi University of Chinese Medicine, Jinzhong, 030619, People's Republic of China. .; Basic Laboratory of Integrated Traditional Chinese and Western Medicine, Shanxi University of Chinese Medicine, Jinzhong, 030619, People's Republic of China. .
Liu Y; College of Basic Medical Sciences, Shanxi University of Chinese Medicine, Jinzhong, 030619, People's Republic of China. .; Basic Laboratory of Integrated Traditional Chinese and Western Medicine, Shanxi University of Chinese Medicine, Jinzhong, 030619, People's Republic of China. .
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Źródło:
BMC medical genomics [BMC Med Genomics] 2022 Dec 25; Vol. 15 (1), pp. 270. Date of Electronic Publication: 2022 Dec 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Hepatitis, Autoimmune*/genetics
MicroRNAs*/genetics
MicroRNAs*/metabolism
RNA, Long Noncoding*/genetics
RNA, Long Noncoding*/metabolism
RNA, Messenger*/genetics
RNA, Messenger*/metabolism
Animals ; Mice ; Gene Regulatory Networks ; Oligonucleotide Array Sequence Analysis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
LncRNA and mRNA profiles of human milk-derived exosomes and their possible roles in protecting against necrotizing enterocolitis.
Autorzy:
Yan X; Department of Paediatrics, Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing 210004, Jiangsu, China. .
Liu L; Department of Paediatrics, Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing 210004, Jiangsu, China. .
Yao S; Department of Paediatrics, Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing 210004, Jiangsu, China. .
Chen Y; Department of Paediatrics, Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing 210004, Jiangsu, China. .
Yu Q; Department of Paediatrics, Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing 210004, Jiangsu, China. .
Jiang C; Department of Paediatrics, Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing 210004, Jiangsu, China. .
Chen W; Department of Paediatrics, Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing 210004, Jiangsu, China. .
Chen X; Department of Paediatrics, Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing 210004, Jiangsu, China. .
Han S; Department of Paediatrics, Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing 210004, Jiangsu, China. .
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Źródło:
Food & function [Food Funct] 2022 Dec 13; Vol. 13 (24), pp. 12953-12965. Date of Electronic Publication: 2022 Dec 13.
Typ publikacji:
Journal Article
MeSH Terms:
Enterocolitis, Necrotizing*/prevention & control
Exosomes*
Milk, Human*/cytology
RNA, Long Noncoding*/genetics
RNA, Long Noncoding*/metabolism
RNA, Messenger*/genetics
RNA, Messenger*/metabolism
Animals ; Female ; Humans ; Rats ; Lactation ; Disease Models, Animal
Czasopismo naukowe
Szczegóły
Tytuł:
Principles of gene regulation quantitatively connect DNA to RNA and proteins in bacteria.
Autorzy:
Balakrishnan R; Department of Physics, University of California at San Diego, La Jolla, CA 92093, USA.
Mori M; Department of Physics, University of California at San Diego, La Jolla, CA 92093, USA.
Segota I; Departments of Medicine and Pharmacology, University of California at San Diego, La Jolla, CA 92093, USA.
Zhang Z; Section of Molecular Biology, Division of Biological Sciences, University of California at San Diego, La Jolla, CA 92093, USA.
Aebersold R; Faculty of Science, University of Zurich, Zürich, Switzerland.; Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, Zürich, Switzerland.
Ludwig C; Bavarian Center for Biomolecular Mass Spectrometry (BayBioMS), Technical University of Munich (TUM), Freising, Germany.
Hwa T; Department of Physics, University of California at San Diego, La Jolla, CA 92093, USA.; Section of Molecular Biology, Division of Biological Sciences, University of California at San Diego, La Jolla, CA 92093, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2022 Dec 09; Vol. 378 (6624), pp. eabk2066. Date of Electronic Publication: 2022 Dec 09.
Typ publikacji:
Journal Article
MeSH Terms:
Gene Expression Regulation, Bacterial*
Protein Biosynthesis*/genetics
Escherichia coli*/genetics
RNA, Messenger*/genetics
RNA, Messenger*/metabolism
RNA, Bacterial/genetics ; DNA, Bacterial/genetics ; Promoter Regions, Genetic ; Transcription, Genetic
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
RNA-methyltransferase Nsun5 controls the maternal-to-zygotic transition by regulating maternal mRNA stability.
Autorzy:
Ding C; State Key Laboratory of Reproductive Medicine, Suzhou Affiliated Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, China.
Lu J; State Key Laboratory of Reproductive Medicine, Suzhou Affiliated Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, China.
Li J; State Key Laboratory of Reproductive Medicine, Suzhou Affiliated Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, China.
Hu X; State Key Laboratory of Reproductive Medicine, Suzhou Affiliated Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, China.
Liu Z; State Key Laboratory of Reproductive Medicine, Suzhou Affiliated Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, China.
Su H; State Key Laboratory of Reproductive Medicine, Suzhou Affiliated Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, China.
Li H; State Key Laboratory of Reproductive Medicine, Suzhou Affiliated Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, China.
Huang B; State Key Laboratory of Reproductive Medicine, Suzhou Affiliated Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, China.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2022 Dec; Vol. 12 (12), pp. e1137.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
RNA, Messenger, Stored*/genetics
RNA, Messenger, Stored*/metabolism
Methyltransferases*/genetics
Methyltransferases*/metabolism
Pregnancy ; Female ; Mice ; Animals ; RNA/metabolism ; Zygote/metabolism ; RNA Stability/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Rapid Generation of Circulating and Mucosal Decoy Human ACE2 using mRNA Nanotherapeutics for the Potential Treatment of SARS-CoV-2.
Autorzy:
Kim J; Department of Pharmaceutical Sciences, College of Pharmacy, Robertson Life Sciences Building, Oregon State University, Portland, OR, 97201, USA.
Jozic A; Department of Pharmaceutical Sciences, College of Pharmacy, Robertson Life Sciences Building, Oregon State University, Portland, OR, 97201, USA.
Mukherjee A; Department of Pharmaceutical Sciences, College of Pharmacy, Robertson Life Sciences Building, Oregon State University, Portland, OR, 97201, USA.
Nelson D; Department of Pharmaceutical Sciences, College of Pharmacy, Robertson Life Sciences Building, Oregon State University, Portland, OR, 97201, USA.; High-Throughput Screening Services Laboratory, College of Pharmacy, Oregon State University, Corvallis, OR, 97331, USA.
Chiem K; Disease Prevention and Intervention, and Population Health Programs, Texas Biomedical Research Institute, San Antonio, TX, 78227, USA.
Khan MSR; Disease Prevention and Intervention, and Population Health Programs, Texas Biomedical Research Institute, San Antonio, TX, 78227, USA.
Torrelles JB; Disease Prevention and Intervention, and Population Health Programs, Texas Biomedical Research Institute, San Antonio, TX, 78227, USA.
Martinez-Sobrido L; Disease Prevention and Intervention, and Population Health Programs, Texas Biomedical Research Institute, San Antonio, TX, 78227, USA.
Sahay G; Department of Pharmaceutical Sciences, College of Pharmacy, Robertson Life Sciences Building, Oregon State University, Portland, OR, 97201, USA.; Department of Biomedical Engineering, Robertson Life Sciences Building, Oregon Health & Science University, Portland, OR, 97201, USA.; Department of Ophthalmology, Casey Eye Institute, Oregon Health & Science University, Portland, OR, 97239, USA.
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Źródło:
Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2022 Dec; Vol. 9 (35), pp. e2202556. Date of Electronic Publication: 2022 Oct 10.
Typ publikacji:
Journal Article
MeSH Terms:
Angiotensin-Converting Enzyme 2*/biosynthesis
Angiotensin-Converting Enzyme 2*/blood
Angiotensin-Converting Enzyme 2*/genetics
COVID-19*/therapy
SARS-CoV-2*/enzymology
RNA, Messenger*/administration & dosage
RNA, Messenger*/genetics
Humans
Czasopismo naukowe
Szczegóły
Tytuł:
Recurrent RNA edits in human preimplantation potentially enhance maternal mRNA clearance.
Autorzy:
Ding Y; Institute of Health Service and Transfusion Medicine, Beijing, 100850, China.; Biomedical Pioneering Innovation Center (BIOPIC), Beijing Advanced Innovation Center for Genomics (ICG), Center for Bioinformatics (CBI), and State Key Laboratory of Protein and Plant Gene Research at School of Life Sciences, Peking University, Beijing, 100871, China.
Zheng Y; Institute of Health Service and Transfusion Medicine, Beijing, 100850, China.; State Key Laboratory of NBC Protection for Civilian, Beijing, 102205, China.
Wang J; Institute of Health Service and Transfusion Medicine, Beijing, 100850, China.
Li H; Institute of Health Service and Transfusion Medicine, Beijing, 100850, China.
Zhao C; Medical Innovation Research Division of Chinese PLA General Hospital, Beijing, 100853, China.
Tao H; Institute of Health Service and Transfusion Medicine, Beijing, 100850, China.
Li Y; Institute of Health Service and Transfusion Medicine, Beijing, 100850, China.
Xu K; Institute of Health Service and Transfusion Medicine, Beijing, 100850, China.
Huang X; Beijing Institute of Radiation Medicine, Beijing, 100850, China.
Gao G; Biomedical Pioneering Innovation Center (BIOPIC), Beijing Advanced Innovation Center for Genomics (ICG), Center for Bioinformatics (CBI), and State Key Laboratory of Protein and Plant Gene Research at School of Life Sciences, Peking University, Beijing, 100871, China. .
Chen H; Institute of Health Service and Transfusion Medicine, Beijing, 100850, China. .
Bo X; Institute of Health Service and Transfusion Medicine, Beijing, 100850, China. .
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Źródło:
Communications biology [Commun Biol] 2022 Dec 21; Vol. 5 (1), pp. 1400. Date of Electronic Publication: 2022 Dec 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
RNA, Messenger, Stored*/metabolism
RNA Editing*
Humans ; Embryonic Development/genetics ; Exons ; RNA/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Prognosis prediction of stage IV colorectal cancer patients by mRNA transcriptional profile.
Autorzy:
Wu B; Department of General Surgery II, the First People's Hospital of Yunnan Province, Kunming, Yunnan, China.
Yang J; Department of General Surgery II, the First People's Hospital of Yunnan Province, Kunming, Yunnan, China.
Qin Z; Department of General Surgery, Wenshan people's Hospital of Yunnan Province, Yunnan, China.
Yang H; Department of Anus and Intestine Surgery, Qujing Hospital of Traditional Chinese Medicine, Qujing, Yunnan, China.
Shao J; Department of Reproductive Medicine, the First People's Hospital of Yunnan Province, Kunming, Yunnan, China.
Shang Y; Department of General Surgery II, the First People's Hospital of Yunnan Province, Kunming, Yunnan, China.
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Źródło:
Cancer medicine [Cancer Med] 2022 Dec; Vol. 11 (24), pp. 4900-4912. Date of Electronic Publication: 2022 May 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/pathology
Liver Neoplasms*/secondary
RNA, Messenger*/genetics
Humans ; Mutation ; Neoplasm Staging ; Prognosis ; Retrospective Studies
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Mammalian oocytes store mRNAs in a mitochondria-associated membraneless compartment.
Autorzy:
Cheng S; Department of Meiosis, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.
Altmeppen G; Department of Meiosis, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.
So C; Department of Meiosis, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.
Welp LM; Bioanalytical Mass Spectrometry Group, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.
Penir S; Department of Meiosis, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.
Ruhwedel T; Electron Microscopy City Campus, Department of Neurogenetics, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.
Menelaou K; Department of Meiosis, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.; Bourn Hall Clinic, Cambridge, UK.
Harasimov K; Department of Meiosis, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.
Stützer A; Bioanalytical Mass Spectrometry Group, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.
Blayney M; Bourn Hall Clinic, Cambridge, UK.
Elder K; Bourn Hall Clinic, Cambridge, UK.
Möbius W; Electron Microscopy City Campus, Department of Neurogenetics, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC), University of Göttingen, Göttingen, Germany.
Urlaub H; Bioanalytical Mass Spectrometry Group, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.; Bioanalytics Group, Institute for Clinical Chemistry, University Medical Center Göttingen, Göttingen, Germany.
Schuh M; Department of Meiosis, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC), University of Göttingen, Göttingen, Germany.
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Źródło:
Science (New York, N.Y.) [Science] 2022 Oct 21; Vol. 378 (6617), pp. eabq4835. Date of Electronic Publication: 2022 Oct 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Mitochondria*/genetics
Mitochondria*/metabolism
Oocytes*/metabolism
RNA, Messenger, Stored*/genetics
RNA, Messenger, Stored*/metabolism
Animals ; Female ; Hydrogels ; RNA-Binding Proteins/genetics ; RNA-Binding Proteins/metabolism ; Humans ; Mice ; Swine ; Cattle ; Egg Proteins/genetics ; Egg Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The amino acid sensor GCN2 suppresses terminal oligopyrimidine (TOP) mRNA translation via La-related protein 1 (LARP1).
Autorzy:
Farooq Z; Department of Pharmacology and Regenerative Medicine, University of Illinois College of Medicine, Chicago, Illinois, USA.
Kusuma F; Soonchunhyang Institute of Medi-bio Science (SIMS), Soonchunhyang University, Cheonan-si, Chungcheongnam-do, Korea.
Burke P; Basic Sciences Division and Computational Biology Section of the Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Dufour CR; Goodman Cancer Research Centre, McGill University, Montréal, Quebec, Canada.
Lee D; Soonchunhyang Institute of Medi-bio Science (SIMS), Soonchunhyang University, Cheonan-si, Chungcheongnam-do, Korea.
Tabatabaei N; Department of Pharmacology and Regenerative Medicine, University of Illinois College of Medicine, Chicago, Illinois, USA.
Toboz P; Department of Pharmacology and Regenerative Medicine, University of Illinois College of Medicine, Chicago, Illinois, USA.
Radovani E; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
Greenblatt JF; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
Rehman J; Department of Pharmacology and Regenerative Medicine, University of Illinois College of Medicine, Chicago, Illinois, USA.
Class J; Department of Microbiology and Immunology, University of Illinois College of Medicine, Chicago, Illinois, USA.
Khoutorsky A; Department of Anesthesia and Faculty of Dentistry, McGill University, Montreal, Quebec, Canada.
Fonseca BD; PrimerGen Ltd, Viseu, Portugal.
Richner JM; Department of Microbiology and Immunology, University of Illinois College of Medicine, Chicago, Illinois, USA.
Mercier E; Canadian Centre for Computational Genomics, and Department of Human Genetics, McGill Genome Centre, McGill University and Genome Québec Innovation Center, Montréal, Quebec, Canada.
Bourque G; Canadian Centre for Computational Genomics, and Department of Human Genetics, McGill Genome Centre, McGill University and Genome Québec Innovation Center, Montréal, Quebec, Canada.
Giguère V; Goodman Cancer Research Centre, McGill University, Montréal, Quebec, Canada.
Subramaniam AR; Basic Sciences Division and Computational Biology Section of the Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Han J; Soonchunhyang Institute of Medi-bio Science (SIMS), Soonchunhyang University, Cheonan-si, Chungcheongnam-do, Korea. Electronic address: .
Tahmasebi S; Department of Pharmacology and Regenerative Medicine, University of Illinois College of Medicine, Chicago, Illinois, USA. Electronic address: .
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Źródło:
The Journal of biological chemistry [J Biol Chem] 2022 Sep; Vol. 298 (9), pp. 102277. Date of Electronic Publication: 2022 Jul 19.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Amino Acids*/metabolism
Protein Biosynthesis*
Protein Serine-Threonine Kinases*/genetics
Protein Serine-Threonine Kinases*/metabolism
RNA 5' Terminal Oligopyrimidine Sequence*
RNA, Messenger*/genetics
RNA, Messenger*/metabolism
RNA-Binding Proteins*/genetics
RNA-Binding Proteins*/metabolism
Activating Transcription Factor 4/genetics ; Activating Transcription Factor 4/metabolism ; Animals ; Cell Culture Techniques ; Chromatin Immunoprecipitation ; Eukaryotic Initiation Factor-4E/metabolism ; Fibroblasts ; Mechanistic Target of Rapamycin Complex 1/metabolism ; Mice ; Mice, Knockout
Czasopismo naukowe
Szczegóły
Tytuł:
mRNA 5' terminal sequences drive 200-fold differences in expression through effects on synthesis, translation and decay.
Autorzy:
van den Elzen AMG; Department of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, Connecticut, United States of America.
Watson MJ; Department of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, Connecticut, United States of America.
Thoreen CC; Department of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, Connecticut, United States of America.
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Źródło:
PLoS genetics [PLoS Genet] 2022 Nov 28; Vol. 18 (11), pp. e1010532. Date of Electronic Publication: 2022 Nov 28 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
RNA, Messenger*/genetics
Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Identification and characterization of unique and common lncRNAs and mRNAs in the pituitary, ovary, and uterus of Hu sheep with different prolificacy.
Autorzy:
Yao X; Hu Sheep Academy, Nanjing Agricultural University, Nanjing 210095, China; Jiangsu Livestock Embryo Engineering Laboratory, Nanjing Agricultural University, Nanjing 210095, China.
Yang F; Hu Sheep Academy, Nanjing Agricultural University, Nanjing 210095, China; Jiangsu Livestock Embryo Engineering Laboratory, Nanjing Agricultural University, Nanjing 210095, China.
El-Samahy MA; Hu Sheep Academy, Nanjing Agricultural University, Nanjing 210095, China; Jiangsu Livestock Embryo Engineering Laboratory, Nanjing Agricultural University, Nanjing 210095, China.
Liu B; Nei Mongol BioNew Technology Co., Ltd., Hohhot 010000, China.
Zhao B; Hu Sheep Academy, Nanjing Agricultural University, Nanjing 210095, China; Jiangsu Livestock Embryo Engineering Laboratory, Nanjing Agricultural University, Nanjing 210095, China.
Gao X; Hu Sheep Academy, Nanjing Agricultural University, Nanjing 210095, China; Jiangsu Livestock Embryo Engineering Laboratory, Nanjing Agricultural University, Nanjing 210095, China.
Zheng J; Hu Sheep Academy, Nanjing Agricultural University, Nanjing 210095, China; Jiangsu Livestock Embryo Engineering Laboratory, Nanjing Agricultural University, Nanjing 210095, China.
Feng X; Hu Sheep Academy, Nanjing Agricultural University, Nanjing 210095, China; Jiangsu Livestock Embryo Engineering Laboratory, Nanjing Agricultural University, Nanjing 210095, China.
Fan Y; Hu Sheep Academy, Nanjing Agricultural University, Nanjing 210095, China; Jiangsu Livestock Embryo Engineering Laboratory, Nanjing Agricultural University, Nanjing 210095, China.
Wang F; Hu Sheep Academy, Nanjing Agricultural University, Nanjing 210095, China; Jiangsu Livestock Embryo Engineering Laboratory, Nanjing Agricultural University, Nanjing 210095, China.
Zhang Y; Hu Sheep Academy, Nanjing Agricultural University, Nanjing 210095, China; Jiangsu Livestock Embryo Engineering Laboratory, Nanjing Agricultural University, Nanjing 210095, China. Electronic address: .
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Źródło:
Genomics [Genomics] 2022 Nov; Vol. 114 (6), pp. 110511. Date of Electronic Publication: 2022 Oct 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
RNA, Messenger*/genetics
Female ; Sheep/genetics ; Animals
Czasopismo naukowe
Szczegóły
Tytuł:
Comprehensive analysis of the lncRNAs, mRNAs, and miRNAs implicated in the immune response of Pinctada fucata martensii to Vibrio parahaemolyticus.
Autorzy:
Zhang B; Fisheries College of Guangdong Ocean University, Zhanjiang, Guangdong, 524088, China.
Liang H; Fisheries College of Guangdong Ocean University, Zhanjiang, Guangdong, 524088, China; Guangdong Provincial Key Laboratory of Aquatic Animal Disease Control and Healthy Culture, Zhanjiang, Guangdong, 524088, China. Electronic address: .
Zou H; Fisheries College of Guangdong Ocean University, Zhanjiang, Guangdong, 524088, China.
Lu J; Fisheries College of Guangdong Ocean University, Zhanjiang, Guangdong, 524088, China.
Zhang M; Fisheries College of Guangdong Ocean University, Zhanjiang, Guangdong, 524088, China.
Liang B; Fisheries College of Guangdong Ocean University, Zhanjiang, Guangdong, 524088, China.
Pokaż więcej
Źródło:
Fish & shellfish immunology [Fish Shellfish Immunol] 2022 Nov; Vol. 130, pp. 132-140. Date of Electronic Publication: 2022 Sep 07.
Typ publikacji:
Journal Article
MeSH Terms:
MicroRNAs*/genetics
Pinctada*/genetics
Pinctada*/immunology
RNA, Long Noncoding*/genetics
RNA, Messenger*/genetics
Vibrio parahaemolyticus*/pathogenicity
Animals ; Immunity ; NF-kappa B/metabolism ; Vascular Endothelial Growth Factor A/metabolism
Czasopismo naukowe
Szczegóły
Wyświetlanie 1-20 z 170427

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