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Wyszukujesz frazę ""RNA, Messenger metabolism"" wg kryterium: Temat


Tytuł :
Sequencing metabolically labeled transcripts in single cells reveals mRNA turnover strategies
Autorzy :
Battich, Nico
Beumer, Joep
de Barbanson, Buys
Krenning, Lenno
Baron, Chloé S
Tanenbaum, Marvin E
Clevers, Hans
van Oudenaarden, Alexander
Pokaż więcej
Temat :
Animals
Humans
Indicators and Reagents/chemistry
K562 Cells
Mice
RNA Stability
RNA, Messenger/metabolism
Sequence Analysis, RNA/methods
Single-Cell Analysis/methods
Transcription, Genetic
Uridine/analogs & derivatives
Źródło :
Science, 367(6482), 1151 - 1156. American Association for the Advancement of Science (AAAS)
Tytuł :
Charting DENR-dependent translation reinitiation uncovers predictive uORF features and links to circadian timekeeping via Clock
Autorzy :
Castelo-Szekely, Violeta
De Matos, Mara
Tusup, Marina
Pascolo, Steve
Ule, Jernej
Gatfield, David
Pokaż więcej
Temat :
5' Untranslated Regions
Animals
CLOCK Proteins/genetics
CLOCK Proteins/metabolism
Circadian Rhythm
Cloning, Molecular
Codon, Initiator
Eukaryotic Initiation Factors/genetics
Eukaryotic Initiation Factors/metabolism
Fibroblasts/metabolism
Gene Expression Regulation
HEK293 Cells
Humans
Luciferases/metabolism
Mice
Mutation
NIH 3T3 Cells
Open Reading Frames
RNA, Messenger/metabolism
Ribosomes/metabolism
Genetics
Dermatology Clinic
610 Medicine & health
Genomics
Źródło :
Nucleic acids research, vol. 47, no. 10, pp. 5193-5209
Castelo-Szekely, Violeta; De Matos, Mara; Tusup, Marina; Pascolo, Steve; Ule, Jernej; Gatfield, David (2019). Charting DENR-dependent translation reinitiation uncovers predictive uORF features and links to circadian timekeeping via Clock. Nucleic Acids Research, 47(10):5193-5209.
Opis pliku :
application/pdf
Tytuł :
Phase 1 Trial of an RNA Interference Therapy for Acute Intermittent Porphyria
Autorzy :
Sardh, Eliane
Harper, Pauline
Balwani, Manisha
Stein, Penelope
Rees, David C.
Bissell, D Montgomery
Desnick, Robert
Parker, Charles
Phillips, John
Bonkovsky, Herbert L
Vassiliou, Daphne
Penz, Craig
Chan-Daniels, Amy
He, Qiuling
Querbes, William
Fitzgerald, Kevin
Kim, Jae B
Garg, Pushkal
Vaishnaw, Akshay
Simon, Amy R
Anderson, Karl E
Pokaż więcej
Temat :
Adult
Dose-Response Relationship, Drug
Drug Administration Schedule
Female
Humans
Injections, Subcutaneous
Liver/metabolism
Male
Middle Aged
Molecular Targeted Therapy
Porphobilinogen/blood
Porphyria, Acute Intermittent/drug therapy
RNA, Messenger/metabolism
RNAi Therapeutics
Źródło :
Sardh, E, Harper, P, Balwani, M, Stein, P, Rees, D C, Bissell, D M, Desnick, R, Parker, C, Phillips, J, Bonkovsky, H L, Vassiliou, D, Penz, C, Chan-Daniels, A, He, Q, Querbes, W, Fitzgerald, K, Kim, J B, Garg, P, Vaishnaw, A, Simon, A R & Anderson, K E 2019, ' Phase 1 Trial of an RNA Interference Therapy for Acute Intermittent Porphyria ', New England Journal of Medicine, vol. 380, no. 6, pp. 549-558 . https://doi.org/10.1056/NEJMoa1807838
Opis pliku :
application/pdf
Tytuł :
Exosomal Expression of CXCR4 Targets Cardioprotective Vesicles to Myocardial Infarction and Improves Outcome after Systemic Administration
Autorzy :
Ciullo, Alessandra
Biemmi, Vanessa
Milano, Giuseppina
Bolis, Sara
Cervio, Elisabetta
Fertig, Emanuel Tudor
Gherghiceanu, Mihaela
Moccetti, Tiziano
Camici, Giovanni G
Vassalli, Giuseppe
Barile, Lucio
Pokaż więcej
Temat :
Chemistry
610 Medicine & health
QD1-999
Cardiocentro Ticino
Article
QH301-705.5
cardiac progenitor cells
carbohydrates (lipids)
fungi
exosomes
macromolecular substances
Animals
Blotting, Western
Cell Survival/drug effects
Cell Survival/genetics
Cell Survival/physiology
Cells, Cultured
Chemokine CXCL12/genetics
Chemokine CXCL12/metabolism
Cryoelectron Microscopy
Enzyme-Linked Immunosorbent Assay
Exosomes/metabolism
Flow Cytometry
Fluorescent Antibody Technique
Heterocyclic Compounds/therapeutic use
Humans
Male
Myocardial Infarction/genetics
Myocardial Infarction/metabolism
Myocardial Infarction/therapy
RNA, Messenger/genetics
RNA, Messenger/metabolism
Rats
Rats, Wistar
Receptors, CXCR4/antagonists & inhibitors
Receptors, CXCR4/genetics
Receptors, CXCR4/metabolism
CXCR4
intravenous injection
Clinic for Cardiology
Biology (General)
Źródło :
Ciullo, Alessandra; Biemmi, Vanessa; Milano, Giuseppina; Bolis, Sara; Cervio, Elisabetta; Fertig, Emanuel Tudor; Gherghiceanu, Mihaela; Moccetti, Tiziano; Camici, Giovanni G; Vassalli, Giuseppe; Barile, Lucio (2019). Exosomal Expression of CXCR4 Targets Cardioprotective Vesicles to Myocardial Infarction and Improves Outcome after Systemic Administration. International Journal of Molecular Sciences, 20(3):E468.
International Journal of Molecular Sciences
International journal of molecular sciences, vol. 20, no. 3
International Journal of Molecular Sciences, Vol 20, Iss 3, p 468 (2019)
Opis pliku :
application/pdf
Tytuł :
A recessive form of Hyper IgE Syndrome by disruption of ZNF341-dependent STAT3 transcription and activity
Autorzy :
Beziat, Vivien
Li, Juan
Lin, Jian-Xin
Ma, Cindy
Li, Peng
Bousfiha, Aziz
Pellier, Isabelle
Zoghi, Samaneh
Baris, Safa
Keles, Sevgi
Gray, Paul
Du, Ning
Wang, Yi
Zerbib, Yoann
Levy, Romain
Leclercq, Thibaut
About, Frédégonde
Lim, Ai Ing
Rao, Geetha
Payne, Kathryn
Pelham, Simon
Avery, Danielle
Deenick, Elissa
Pillay, Bethany
Chou, Janet
Guery, Romain
Belkadi, Aziz
Guerin, Antoine
Migaud, Melanie
Rattina, Vimel
Ailal, Fatima
Benhsaien, Ibtihal
Bouaziz, Matthieu
Habib, Tanwir
Chaussabel, Damien
Marr, Nico
El-Benna, Jamel
Grimbacher, Bodo
Wargon, Orli
Bustamante, Jacinta
Boisson, Bertrand
Müller-Fleckenstein, Ingrid
Fleckenstein, Bernhard
Chandesris, Marie-Olivia
Titeux, Matthias
Fraitag, Sylvie
Alyanakian, Marie-Alexandra
Leruez-Ville, Marianne
Picard, Capucine
Meyts, Isabelle
Di Santo, James
Hovnanian, Alain
Somer, Ayper
Ozen, Ahmet
Rezaei, Nima
Chatila, Talal
Abel, Laurent
Leonard, Warren
Tangye, Stuart
Puel, Anne
Casanova, Jean-Laurent
Pokaż więcej
Temat :
MESH: Cell Differentiation/immunology
MESH: Th17 Cells/metabolism
MESH: Male
MESH: Gene Expression Regulation/immunology
MESH: RNA, Messenger/metabolism
MESH: Transcription Factors/immunology
[SDV.IMM]Life Sciences [q-bio]/Immunology
MESH: Transcription Factors/metabolism
MESH: Homozygote
MESH: Th2 Cells/metabolism
MESH: Lymphocyte Count
MESH: STAT3 Transcription Factor/immunology
MESH: Transcription Factors/genetics
MESH: Transcription, Genetic/immunology
MESH: Cytokines/metabolism
MESH: Young Adult
MESH: Th17 Cells/immunology
MESH: Cell Nucleus/metabolism
MESH: Female
MESH: Adult
MESH: Cell Differentiation/genetics
MESH: Genes, Recessive/immunology
MESH: Whole Exome Sequencing
MESH: STAT3 Transcription Factor/metabolism
MESH: Adolescent
MESH: Pedigree
MESH: Job Syndrome/blood
MESH: Th2 Cells/immunology
MESH: Consanguinity
MESH: Exons/genetics
MESH: Humans
MESH: Immunoglobulin E/blood
MESH: STAT3 Transcription Factor/genetics
MESH: Cytokines/immunology
Article
MESH: Loss of Function Mutation
MESH: Middle Aged
MESH: Genes, Recessive/genetics
MESH: Promoter Regions, Genetic/genetics
MESH: Zinc Fingers/genetics
MESH: Job Syndrome/immunology
MESH: Immunoglobulin E/immunology
MESH: Job Syndrome/genetics
Źródło :
Science Immunology, American Association for the Advancement of Science, 2018, 3 (24), pp.eaat4956. ⟨10.1126/sciimmunol.aat4956⟩
Tytuł :
Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study
Autorzy :
Pottier, Cyril
Zhou, Xiaolai
Perkerson, Ralph B.
Baker, Matt
Jenkins, Gregory D.
Serie, Daniel J.
Ghidoni, Roberta
Benussi, Luisa
Binetti, Giuliano
López de Munain, Adolfo
Zulaica, Miren
Moreno, Fermin
Le Ber, Isabelle
Pasquier, Florence
Hannequin, Didier
Sánchez-Valle, Raquel
Antonell, Anna
Lladó, Albert
Parsons, Tammee M.
Finch, Ni Cole A.
Finger, Elizabeth C.
Lippa, Carol F.
Huey, Edward D.
Neumann, Manuela
Heutink, Peter
Synofzik, Matthis
Wilke, Carlo
Rissman, Robert A.
Slawek, Jaroslaw
Sitek, Emilia
Johannsen, Peter
Nielsen, Jørgen E.
Ren, Yingxue
van Blitterswijk, Marka
DeJesus-Hernandez, Mariely
Christopher, Elizabeth
Murray, Melissa E.
Bieniek, Kevin F.
Evers, Bret M.
Ferrari, Camilla
Rollinson, Sara
Richardson, Anna
Scarpini, Elio
Fumagalli, Giorgio G.
Padovani, Alessandro
Hardy, John
Momeni, Parastoo
Ferrari, Raffaele
Frangipane, Francesca
Maletta, Raffaele
Anfossi, Maria
Gallo, Maura
Petrucelli, Leonard
Suh, Eun Ran
Lopez, Oscar L.
Wong, Tsz H.
van Rooij, Jeroen G.J.
Seelaar, Harro
Mead, Simon
Caselli, Richard J.
Reiman, Eric M.
Noel Sabbagh, Marwan
Kjolby, Mads
Nykjaer, Anders
Karydas, Anna M.
Boxer, Adam L.
Grinberg, Lea T.
Grafman, Jordan
Spina, Salvatore
Oblak, Adrian
Mesulam, M. Marsel
Weintraub, Sandra
Geula, Changiz
Hodges, John R.
Piguet, Olivier
Brooks, William S.
Irwin, David J.
Trojanowski, John Q.
Lee, Edward B.
Josephs, Keith A.
Parisi, Joseph E.
Ertekin-Taner, Nilüfer
Knopman, David S.
Nacmias, Benedetta
Piaceri, Irene
Bagnoli, Silvia
Sorbi, Sandro
Gearing, Marla
Glass, Jonathan
Beach, Thomas G.
Black, Sandra E.
Masellis, Mario
Rogaeva, Ekaterina
Vonsattel, Jean Paul
Honig, Lawrence S.
Kofler, Julia
Bruni, Amalia C.
Snowden, Julie
Mann, David
Pickering-Brown, Stuart
Diehl-Schmid, Janine
Winkelmann, Juliane
Galimberti, Daniela
Graff, Caroline
Öijerstedt, Linn
Troakes, Claire
Al-Sarraj, Safa
Cruchaga, Carlos
Cairns, Nigel J.
Rohrer, Jonathan D.
Halliday, Glenda M.
Kwok, John B.
van Swieten, John C.
White, Charles L.
Ghetti, Bernardino
Murell, Jill R.
Mackenzie, Ian R.A.
Hsiung, Ging Yuek R.
Borroni, Barbara
Rossi, Giacomina
Tagliavini, Fabrizio
Wszolek, Zbigniew K.
Petersen, Ronald C.
Bigio, Eileen H.
Grossman, Murray
Van Deerlin, Vivianna M.
Seeley, William W.
Miller, Bruce L.
Graff-Radford, Neill R.
Boeve, Bradley F.
Dickson, Dennis W.
Biernacka, Joanna M.
Rademakers, Rosa
Pokaż więcej
Temat :
Mutation/genetics
b_open_article_in_toll_access_journal
RNA, Messenger/metabolism
Aged
Progranulins/genetics
Middle Aged
Frontotemporal Lobar Degeneration/genetics
Glial Cell Line-Derived Neurotrophic Factor Receptors/genetics
Cerebellum/metabolism
Genetic Predisposition to Disease/genetics
Genome-Wide Association Study
Female
Humans
Male
Age of Onset
Case-Control Studies
Źródło :
Pottier, C, Zhou, X, Perkerson, R B, Baker, M, Jenkins, G D, Serie, D J, Ghidoni, R, Benussi, L, Binetti, G, López de Munain, A, Zulaica, M, Moreno, F, Le Ber, I, Pasquier, F, Hannequin, D, Sánchez-Valle, R, Antonell, A, Lladó, A, Parsons, T M, Finch, N C A, Finger, E C, Lippa, C F, Huey, E D, Neumann, M, Heutink, P, Synofzik, M, Wilke, C, Rissman, R A, Slawek, J, Sitek, E, Johannsen, P, Nielsen, J E, Ren, Y, van Blitterswijk, M, DeJesus-Hernandez, M, Christopher, E, Murray, M E, Bieniek, K F, Evers, B M, Ferrari, C, Rollinson, S, Richardson, A, Scarpini, E, Fumagalli, G G, Padovani, A, Hardy, J, Momeni, P, Ferrari, R, Frangipane, F, Maletta, R, Anfossi, M, Gallo, M, Petrucelli, L, Suh, E R, Lopez, O L, Wong, T H, van Rooij, J G J, Seelaar, H, Mead, S, Caselli, R J, Reiman, E M, Noel Sabbagh, M, Kjolby, M, Nykjaer, A, Karydas, A M, Boxer, A L, Grinberg, L T, Grafman, J, Spina, S, Oblak, A, Mesulam, M M, Weintraub, S, Geula, C, Hodges, J R, Piguet, O, Brooks, W S, Irwin, D J, Trojanowski, J Q, Lee, E B, Josephs, K A, Parisi, J E, Ertekin-Taner, N, Knopman, D S, Nacmias, B, Piaceri, I, Bagnoli, S, Sorbi, S, Gearing, M, Glass, J, Beach, T G, Black, S E, Masellis, M, Rogaeva, E, Vonsattel, J P, Honig, L S, Kofler, J, Bruni, A C, Snowden, J, Mann, D, Pickering-Brown, S, Diehl-Schmid, J, Winkelmann, J, Galimberti, D, Graff, C, Öijerstedt, L, Troakes, C, Al-Sarraj, S, Cruchaga, C, Cairns, N J, Rohrer, J D, Halliday, G M, Kwok, J B, van Swieten, J C, White, C L, Ghetti, B, Murell, J R, Mackenzie, I R A, Hsiung, G Y R, Borroni, B, Rossi, G, Tagliavini, F, Wszolek, Z K, Petersen, R C, Bigio, E H, Grossman, M, Van Deerlin, V M, Seeley, W W, Miller, B L, Graff-Radford, N R, Boeve, B F, Dickson, D W, Biernacka, J M & Rademakers, R 2018, ' Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations : a genome-wide association study ', The Lancet Neurology, vol. 17, no. 6, pp. 548-558 . https://doi.org/10.1016/S1474-4422(18)30126-1
The Lancet Neurology, 17(6), 548 - 558. Lancet Publishing Group
Tytuł :
Selective localization of IgG from cerebrospinal fluid to brain parenchyma
Autorzy :
Owens, Trevor
Mørch, Marlene Thorsen
Sørensen, Sofie Forsberg
Khorooshi, Reza
Asgari, Nasrin
Pokaż więcej
Temat :
Aquaporin 4/immunology
Pathology
Neurology. Diseases of the nervous system
Neuromyelitis Optica/metabolism
Glial Fibrillary Acidic Protein/metabolism
RNA, Messenger/metabolism
RC346-429
Deposition
Immunoglobulin G/administration & dosage
Protein Transport/drug effects
Central Nervous System/anatomy & histology
Parenchymal Tissue/metabolism
Mice
Neuromyelitis optica spectrum disorders
Immunoglobulin-G
Mice, Inbred C57BL
Time Factors
Cerebrospinal fluid
Dextrans/metabolism
Short Report
Animals
Cytokines/genetics
Female
Humans
Źródło :
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-8 (2018)
Mørch, M T, Forsberg Sørensen, S, Khorooshi, R M H, Asgari, N & Owens, T 2018, ' Selective localization of IgG from cerebrospinal fluid to brain parenchyma ', Journal of Neuroinflammation, vol. 15, 110 . https://doi.org/10.1186/s12974-018-1159-8
Journal of Neuroinflammation
Opis pliku :
application/pdf
Tytuł :
Gene expression profiling of fast- and slow-growing non-functioning gonadotroph pituitary adenomas
Autorzy :
Falch, Camilla Maria
Sundaram, Arvind Y M
Øystese, Kristin Astrid
Normann, Kjersti Ringvoll
Lekva, Tove
Silamikelis, Ivars
Eieland, Alexander Kirkeby
Andersen, Marianne Skovsager
Bollerslev, Jens
Olarescu, Nicoleta Cristina
Pokaż więcej
Temat :
Adaptor Proteins, Signal Transducing/genetics
Adenoma/genetics
Adult
Aged
Cadherins/genetics
Cell Adhesion Molecules/genetics
Cell Movement/genetics
Cyclic AMP-Dependent Protein Kinase Catalytic Subunits/genetics
Epithelial-Mesenchymal Transition/genetics
Female
Follicle Stimulating Hormone/metabolism
Gene Expression Profiling
Gene Expression Regulation, Neoplastic
Gene Silencing
Humans
In Vitro Techniques
Intracellular Signaling Peptides and Proteins/genetics
Luteinizing Hormone/metabolism
Male
Membrane Glycoproteins/genetics
Microtubule-Associated Proteins/genetics
Middle Aged
Myosin Type I/genetics
Nerve Tissue Proteins/genetics
Pituitary Neoplasms/genetics
Proto-Oncogene Proteins/genetics
RNA, Messenger/metabolism
Receptors, Cell Surface/genetics
Reverse Transcriptase Polymerase Chain Reaction
Ribonucleases/genetics
Sialoglycoproteins/genetics
Time Factors
Źródło :
Falch, C M, Sundaram, A Y M, Øystese, K A, Normann, K R, Lekva, T, Silamikelis, I, Eieland, A K, Andersen, M S, Bollerslev, J & Olarescu, N C 2018, ' Gene expression profiling of fast- and slow-growing non-functioning gonadotroph pituitary adenomas ', European Journal of Endocrinology, vol. 178, no. 3, pp. 295-307 . https://doi.org/10.1530/EJE-17-0702

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