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Tytuł:
Liquid-based biomarkers in breast cancer: looking beyond the blood.
Autorzy:
Shuai Y; Department of VIP Medical Services, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Ma Z; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Endoscopy, Peking University Cancer Hospital & Institute, Beijing, 100142, China.
Ju J; Department of VIP Medical Services, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Wei T; Department of VIP Medical Services, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Gao S; Department of VIP Medical Services, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Kang Y; Department of VIP Medical Services, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Yang Z; Department of VIP Medical Services, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Wang X; Department of VIP Medical Services, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Yue J; Department of VIP Medical Services, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Yuan P; Department of VIP Medical Services, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China. .
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Źródło:
Journal of translational medicine [J Transl Med] 2023 Nov 13; Vol. 21 (1), pp. 809. Date of Electronic Publication: 2023 Nov 13.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Breast Neoplasms*/diagnosis
Neoplastic Cells, Circulating*/pathology
Humans ; Female ; Biomarkers, Tumor/genetics ; Liquid Biopsy ; DNA, Neoplasm/genetics ; RNA, Neoplasm
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
LINC01116 Promotes Migration and Invasion of Oral Squamous Cell Carcinoma by Acting as a Competed Endogenous RNA in Regulation of MMP1 Expression.
Autorzy:
Ying Y; Department of Stomatology, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, 318000 Zhejiang Province, China.
Liu D; Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, 230000 Anhui Province, China.
Zhao Y; Department of Stomatology, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, 318000 Zhejiang Province, China.
Zhong Y; Department of Stomatology, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, 318000 Zhejiang Province, China.
Xu X; Department of Stomatology, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, 318000 Zhejiang Province, China.
Luo J; Department of Stomatology, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, 318000 Zhejiang Province, China.
Zhang Z; Department of Stomatology, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, 318000 Zhejiang Province, China.
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Źródło:
Computational and mathematical methods in medicine [Comput Math Methods Med] 2022 Jun 17; Vol. 2022, pp. 2857022. Date of Electronic Publication: 2022 Jun 17 (Print Publication: 2022).
Typ publikacji:
Journal Article; Retracted Publication
MeSH Terms:
Matrix Metalloproteinase 1*/biosynthesis
Matrix Metalloproteinase 1*/genetics
Matrix Metalloproteinase 1*/metabolism
MicroRNAs*/genetics
MicroRNAs*/metabolism
Mouth Neoplasms*/genetics
Mouth Neoplasms*/metabolism
Mouth Neoplasms*/pathology
RNA, Long Noncoding*/genetics
RNA, Long Noncoding*/metabolism
RNA, Neoplasm*/genetics
RNA, Neoplasm*/metabolism
Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation/genetics ; Humans ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Squamous Cell Carcinoma of Head and Neck/genetics ; Squamous Cell Carcinoma of Head and Neck/metabolism ; Squamous Cell Carcinoma of Head and Neck/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Analyses of human cancer driver genes uncovers evolutionarily conserved RNA structural elements involved in posttranscriptional control.
Autorzy:
Tompkins VS; Roy J. Carver Department of Biophysics, Biochemistry and Molecular Biology, Iowa State University, Ames, IA, United States of America.
Rouse WB; Roy J. Carver Department of Biophysics, Biochemistry and Molecular Biology, Iowa State University, Ames, IA, United States of America.
O'Leary CA; Roy J. Carver Department of Biophysics, Biochemistry and Molecular Biology, Iowa State University, Ames, IA, United States of America.
Andrews RJ; Roy J. Carver Department of Biophysics, Biochemistry and Molecular Biology, Iowa State University, Ames, IA, United States of America.
Moss WN; Roy J. Carver Department of Biophysics, Biochemistry and Molecular Biology, Iowa State University, Ames, IA, United States of America.
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Źródło:
PloS one [PLoS One] 2022 Feb 25; Vol. 17 (2), pp. e0264025. Date of Electronic Publication: 2022 Feb 25 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Evolution, Molecular*
Neoplasms*/genetics
Neoplasms*/metabolism
Nucleic Acid Conformation*
Phylogeny*
RNA Processing, Post-Transcriptional*
RNA Stability*
RNA, Neoplasm*/genetics
RNA, Neoplasm*/metabolism
Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Systematic comparative analysis of strand-specific RNA-seq library preparation methods for low input samples.
Autorzy:
Naphade S; Verge Genomics, South San Francisco, CA, USA.
Bhatnagar R; Verge Genomics, South San Francisco, CA, USA. .; Fountain Therapeutics, South San Francisco, CA, USA. .
Hanson-Smith V; Verge Genomics, South San Francisco, CA, USA. .
Choi I; Verge Genomics, South San Francisco, CA, USA.
Zhang A; Verge Genomics, South San Francisco, CA, USA.
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Źródło:
Scientific reports [Sci Rep] 2022 Feb 02; Vol. 12 (1), pp. 1789. Date of Electronic Publication: 2022 Feb 02.
Typ publikacji:
Journal Article
MeSH Terms:
Gene Library*
Transcriptome*
Biomarkers, Tumor/*genetics
Neoplasms/*genetics
RNA, Neoplasm/*analysis
RNA-Seq/*methods
RNA-Seq/*standards
Gene Expression Profiling ; Humans ; Neoplasms/pathology ; RNA, Neoplasm/genetics ; Sequence Analysis, RNA/methods ; Tumor Cells, Cultured
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Role of Exosomal Non-Coding RNAs in Colorectal Cancer Drug Resistance.
Autorzy:
Lampropoulou DI; Second Department of Medical Oncology, General Oncology Hospital of Kifissia 'Agioi Anargiroi', 14564 Athens, Greece.
Pliakou E; Second Department of Medical Oncology, General Oncology Hospital of Kifissia 'Agioi Anargiroi', 14564 Athens, Greece.
Aravantinos G; Second Department of Medical Oncology, General Oncology Hospital of Kifissia 'Agioi Anargiroi', 14564 Athens, Greece.
Filippou D; Department of Anatomy and Surgical Anatomy, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Gazouli M; Laboratory of Biology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Jan 27; Vol. 23 (3). Date of Electronic Publication: 2022 Jan 27.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Colorectal Neoplasms*/drug therapy
Colorectal Neoplasms*/genetics
Colorectal Neoplasms*/metabolism
Exosomes*/genetics
Exosomes*/metabolism
RNA, Neoplasm*/genetics
RNA, Neoplasm*/metabolism
RNA, Untranslated*/genetics
RNA, Untranslated*/metabolism
Drug Resistance, Neoplasm/*genetics
Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
MicroRNA-16 Restores Sensitivity to Tyrosine Kinase Inhibitors and Outperforms MEK Inhibitors in KRAS -Mutated Non-Small Cell Lung Cancer.
Autorzy:
Fanini F; Immuno-Gene Therapy Factory, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', 47014 Meldola, Italy.
Bandini E; Biosciences Laboratory, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', 47014 Meldola, Italy.
Plousiou M; Biosciences Laboratory, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', 47014 Meldola, Italy.
Carloni S; Immuno-Gene Therapy Factory, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', 47014 Meldola, Italy.
Wise P; Department of Microgravity and Translational Regenerative Medicine, Clinic for Plastic, Aesthetic and Hand Surgery, Otto von Guericke University, 39106 Magdeburg, Germany.
Neviani P; Extracellular Vesicle Core, The Saban Research Institute, Children's Hospital Los Angeles, Los Angeles, CA 90027, USA.
Murtadha M; Judy and Bernard Briskin Center for Multiple Myeloma Research, Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Monrovia, CA 91016, USA.
Foca F; Unit of Biostatistics and Clinical Trials, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', 47014 Meldola, Italy.
Fabbri F; Biosciences Laboratory, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', 47014 Meldola, Italy.
Vannini I; Biosciences Laboratory, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', 47014 Meldola, Italy.
Fabbri M; Center for Cancer and Immunology Research, Children's National Hospital, Washington, DC 20010, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Dec 12; Vol. 22 (24). Date of Electronic Publication: 2021 Dec 12.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Non-Small-Cell Lung*/genetics
Carcinoma, Non-Small-Cell Lung*/metabolism
Carcinoma, Non-Small-Cell Lung*/pathology
Carcinoma, Non-Small-Cell Lung*/therapy
Drug Resistance, Neoplasm*/drug effects
Drug Resistance, Neoplasm*/genetics
Lung Neoplasms*/genetics
Lung Neoplasms*/metabolism
Lung Neoplasms*/pathology
Lung Neoplasms*/therapy
MAP Kinase Kinase Kinases*/antagonists & inhibitors
MAP Kinase Kinase Kinases*/genetics
MicroRNAs*/biosynthesis
MicroRNAs*/genetics
Mutation*
Proto-Oncogene Proteins p21(ras)*/genetics
Proto-Oncogene Proteins p21(ras)*/metabolism
RNA, Neoplasm*/biosynthesis
RNA, Neoplasm*/genetics
Protein Kinase Inhibitors/*pharmacology
A549 Cells ; Animals ; Female ; Humans ; Male ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Targeted Long-Read Sequencing Decodes the Transcriptional Atlas of the Founding RAS Gene Family Members.
Autorzy:
Adamopoulos PG; Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, 15701 Athens, Greece.
Tsiakanikas P; Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, 15701 Athens, Greece.
Boti MA; Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, 15701 Athens, Greece.
Scorilas A; Department of Biochemistry and Molecular Biology, Faculty of Biology, National and Kapodistrian University of Athens, 15701 Athens, Greece.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Dec 10; Vol. 22 (24). Date of Electronic Publication: 2021 Dec 10.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinogenesis*/genetics
Carcinogenesis*/metabolism
Gene Expression Profiling*
Neoplasm Proteins*/biosynthesis
Neoplasm Proteins*/genetics
Neoplasms*/enzymology
Neoplasms*/genetics
RNA, Messenger*/biosynthesis
RNA, Messenger*/genetics
RNA, Neoplasm*/biosynthesis
RNA, Neoplasm*/genetics
ras Proteins*/biosynthesis
ras Proteins*/genetics
Cell Line, Tumor ; Humans ; Nanopore Sequencing
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Epitachophoresis is a novel versatile total nucleic acid extraction method.
Autorzy:
Datinska V; Roche Sequencing Solution, Pleasanton, CA, 94588, USA.
Gheibi P; Roche Sequencing Solution, Pleasanton, CA, 94588, USA.
Jefferson K; Roche Sequencing Solution, Pleasanton, CA, 94588, USA.
Yang J; Roche Sequencing Solution, Pleasanton, CA, 94588, USA.
Paladugu S; Roche Sequencing Solution, Pleasanton, CA, 94588, USA.
Dallett C; Roche Sequencing Solution, Pleasanton, CA, 94588, USA.
Voracova I; Institute of Analytical Chemistry, Czech Academy of Sciences, 602 00, Brno, Czech Republic.
Foret F; Institute of Analytical Chemistry, Czech Academy of Sciences, 602 00, Brno, Czech Republic.
Astier Y; Roche Sequencing Solution, Pleasanton, CA, 94588, USA. .
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Źródło:
Scientific reports [Sci Rep] 2021 Nov 23; Vol. 11 (1), pp. 22736. Date of Electronic Publication: 2021 Nov 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Colorectal Neoplasms/*genetics
DNA, Neoplasm/*isolation & purification
High-Throughput Nucleotide Sequencing/*methods
Lung Neoplasms/*genetics
RNA, Neoplasm/*isolation & purification
Colorectal Neoplasms/pathology ; DNA, Neoplasm/analysis ; DNA, Neoplasm/chemistry ; Humans ; Lung Neoplasms/pathology ; RNA, Neoplasm/analysis ; RNA, Neoplasm/chemistry ; Tissue Fixation ; Tumor Cells, Cultured
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Identification of Potential Long Non-Coding RNA Candidates that Contribute to Triple-Negative Breast Cancer in Humans through Computational Approach.
Autorzy:
Rahman MM; Department of Biochemistry and Molecular Biology, University of Rajshahi, Rajshahi 6205, Bangladesh.; Department of Chemistry, Binghamton University, State University of New York, Vestal, New York, NY 13902, USA.
Hossain MT; University of Chinese Academy of Sciences, No.19(A) Yuquan Road, Shijingshan District, Beijing 100049, China.; Joint Engineering Research Center for Health Big Data Intelligent Analysis Technology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.; Department of Statistics, Bangabandhu Sheikh Mujibur Rahaman Science and Technology University, Gopalganj 8100, Bangladesh.
Reza MS; University of Chinese Academy of Sciences, No.19(A) Yuquan Road, Shijingshan District, Beijing 100049, China.; Joint Engineering Research Center for Health Big Data Intelligent Analysis Technology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Peng Y; Department of Pathology, The Shenzhen University School of Medicine, Shenzhen 518060, China.
Feng S; Joint Engineering Research Center for Health Big Data Intelligent Analysis Technology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Wei Y; Joint Engineering Research Center for Health Big Data Intelligent Analysis Technology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Nov 16; Vol. 22 (22). Date of Electronic Publication: 2021 Nov 16.
Typ publikacji:
Journal Article
MeSH Terms:
MicroRNAs/*genetics
RNA, Long Noncoding/*genetics
RNA, Messenger/*genetics
RNA, Neoplasm/*genetics
Triple Negative Breast Neoplasms/*genetics
Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Computational Biology/methods ; Female ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Gene Ontology ; Gene Regulatory Networks ; Humans ; Mammary Glands, Human/metabolism ; Mammary Glands, Human/pathology ; MicroRNAs/classification ; MicroRNAs/metabolism ; Molecular Sequence Annotation ; RNA, Long Noncoding/classification ; RNA, Long Noncoding/metabolism ; RNA, Messenger/classification ; RNA, Messenger/metabolism ; RNA, Neoplasm/classification ; RNA, Neoplasm/metabolism ; Triple Negative Breast Neoplasms/diagnosis ; Triple Negative Breast Neoplasms/metabolism ; Triple Negative Breast Neoplasms/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Identification of melanoma-specific exosomal miRNAs as the potential biomarker for canine oral melanoma.
Autorzy:
Husna AA; The United Graduate School of Veterinary Science, Yamaguchi University, Yamaguchi, Japan.; Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima, Japan.
Rahman MM; Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima, Japan.
Lai YC; Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima, Japan.
Chen HW; Joint Graduate School of Veterinary Medicine, Kagoshima University, Kagoshima, Japan.
Hasan MN; Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima, Japan.
Nakagawa T; Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.
Miura N; The United Graduate School of Veterinary Science, Yamaguchi University, Yamaguchi, Japan.; Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima, Japan.; Joint Graduate School of Veterinary Medicine, Kagoshima University, Kagoshima, Japan.
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Źródło:
Pigment cell & melanoma research [Pigment Cell Melanoma Res] 2021 Nov; Vol. 34 (6), pp. 1062-1073. Date of Electronic Publication: 2021 Aug 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Biomarkers, Tumor*/genetics
Biomarkers, Tumor*/metabolism
Dog Diseases*/genetics
Dog Diseases*/metabolism
Exosomes*/genetics
Exosomes*/metabolism
Melanoma*/genetics
Melanoma*/metabolism
Melanoma*/veterinary
MicroRNAs*/genetics
MicroRNAs*/metabolism
Mouth Neoplasms*/genetics
Mouth Neoplasms*/metabolism
Mouth Neoplasms*/veterinary
RNA, Neoplasm*/genetics
RNA, Neoplasm*/metabolism
Animals ; Dogs
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Antitumor Effect of Regorafenib on MicroRNA Expression in Hepatocellular Carcinoma Cell Lines.
Autorzy:
Takuma K; Department of Gastroenterology and Neurology, Faculty of Medicine, Graduate School of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho 761-0793, Kita-gun, Kagawa, Japan.
Fujihara S; Department of Gastroenterology and Neurology, Faculty of Medicine, Graduate School of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho 761-0793, Kita-gun, Kagawa, Japan.
Fujita K; Department of Gastroenterology and Neurology, Faculty of Medicine, Graduate School of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho 761-0793, Kita-gun, Kagawa, Japan.
Iwama H; Life Science Research Center, Kagawa University, 1750-1 Ikenobe, Miki-cho 761-0793, Kita-gun, Kagawa, Japan.
Nakahara M; Department of Gastroenterology and Neurology, Faculty of Medicine, Graduate School of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho 761-0793, Kita-gun, Kagawa, Japan.
Oura K; Department of Gastroenterology and Neurology, Faculty of Medicine, Graduate School of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho 761-0793, Kita-gun, Kagawa, Japan.
Tadokoro T; Department of Gastroenterology and Neurology, Faculty of Medicine, Graduate School of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho 761-0793, Kita-gun, Kagawa, Japan.
Mimura S; Department of Gastroenterology and Neurology, Faculty of Medicine, Graduate School of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho 761-0793, Kita-gun, Kagawa, Japan.
Tani J; Department of Gastroenterology and Neurology, Faculty of Medicine, Graduate School of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho 761-0793, Kita-gun, Kagawa, Japan.
Shi T; Department of Gastroenterology and Neurology, Faculty of Medicine, Graduate School of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho 761-0793, Kita-gun, Kagawa, Japan.
Morishita A; Department of Gastroenterology and Neurology, Faculty of Medicine, Graduate School of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho 761-0793, Kita-gun, Kagawa, Japan.
Kobara H; Department of Gastroenterology and Neurology, Faculty of Medicine, Graduate School of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho 761-0793, Kita-gun, Kagawa, Japan.
Himoto T; Department of Gastroenterology and Neurology, Faculty of Medicine, Graduate School of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho 761-0793, Kita-gun, Kagawa, Japan.
Masaki T; Department of Gastroenterology and Neurology, Faculty of Medicine, Graduate School of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho 761-0793, Kita-gun, Kagawa, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Jan 31; Vol. 23 (3). Date of Electronic Publication: 2022 Jan 31.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Hepatocellular/*drug therapy
Gene Expression Regulation, Neoplastic/*drug effects
Liver Neoplasms/*drug therapy
MicroRNAs/*biosynthesis
Phenylurea Compounds/*pharmacology
Pyridines/*pharmacology
RNA, Neoplasm/*biosynthesis
Carcinoma, Hepatocellular/genetics ; Carcinoma, Hepatocellular/metabolism ; G1 Phase Cell Cycle Checkpoints/drug effects ; G1 Phase Cell Cycle Checkpoints/genetics ; Hep G2 Cells ; Humans ; Liver Neoplasms/genetics ; Liver Neoplasms/metabolism ; MicroRNAs/genetics ; RNA, Neoplasm/genetics ; Resting Phase, Cell Cycle/drug effects ; Resting Phase, Cell Cycle/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
lncRNA GAS5 Sensitizes Breast Cancer Cells to Ionizing Radiation by Inhibiting DNA Repair.
Autorzy:
Ma Y; Department of Radiation Oncology, The Second Hospital of Jilin University, Changchun, China 130021.
Yu L; Department of Radiation Oncology, The Second Hospital of Jilin University, Changchun, China 130021.
Yan W; Department of Radiation Oncology, The Second Hospital of Jilin University, Changchun, China 130021.
Qiu L; Department of Radiation Oncology, The Second Hospital of Jilin University, Changchun, China 130021.
Zhang J; Department of Radiation Oncology, The Second Hospital of Jilin University, Changchun, China 130021.
Jia X; Department of Radiation Oncology, The Second Hospital of Jilin University, Changchun, China 130021.
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Źródło:
BioMed research international [Biomed Res Int] 2022 Jan 11; Vol. 2022, pp. 1987519. Date of Electronic Publication: 2022 Jan 11 (Print Publication: 2022).
Typ publikacji:
Journal Article
MeSH Terms:
DNA Repair*
X-Rays*
Breast Neoplasms/*metabolism
DNA, Neoplasm/*metabolism
RNA, Long Noncoding/*metabolism
RNA, Neoplasm/*metabolism
Breast Neoplasms/genetics ; DNA, Neoplasm/genetics ; Female ; Humans ; MCF-7 Cells ; RNA, Long Noncoding/genetics ; RNA, Neoplasm/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Comprehensive quantitative analysis of alternative splicing variants reveals the HNF1B mRNA splicing pattern in various tumour and non-tumour tissues.
Autorzy:
Hojny J; Institute of Pathology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Studničkova 2, 12800, Prague 2, Czech Republic.
Michalkova R; Institute of Pathology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Studničkova 2, 12800, Prague 2, Czech Republic.
Krkavcova E; Institute of Pathology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Studničkova 2, 12800, Prague 2, Czech Republic.
Bui QH; Institute of Pathology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Studničkova 2, 12800, Prague 2, Czech Republic.
Bartu M; Institute of Pathology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Studničkova 2, 12800, Prague 2, Czech Republic.
Nemejcova K; Institute of Pathology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Studničkova 2, 12800, Prague 2, Czech Republic.
Kalousova M; Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University and General University Hospital in Prague, Kateřinská 32, 121 08, Prague 2, Czech Republic.
Kleiblova P; Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University and General University Hospital in Prague, Albertov 4, 128 00, Prague 2, Czech Republic.
Dundr P; Institute of Pathology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Studničkova 2, 12800, Prague 2, Czech Republic.
Struzinska I; Institute of Pathology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Studničkova 2, 12800, Prague 2, Czech Republic. .
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Źródło:
Scientific reports [Sci Rep] 2022 Jan 07; Vol. 12 (1), pp. 199. Date of Electronic Publication: 2022 Jan 07.
Typ publikacji:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Alternative Splicing*
Biomarkers, Tumor/*genetics
Hepatocyte Nuclear Factor 1-beta/*genetics
Neoplasms/*genetics
RNA, Messenger/*genetics
RNA, Neoplasm/*genetics
Biomarkers, Tumor/metabolism ; Gene Expression Regulation, Neoplastic ; Hepatocyte Nuclear Factor 1-beta/metabolism ; High-Throughput Nucleotide Sequencing ; Humans ; Neoplasms/metabolism ; Polymerase Chain Reaction ; Protein Isoforms ; RNA, Messenger/metabolism ; RNA, Neoplasm/metabolism ; Retrospective Studies
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
MiR-133a-3p inhibits the malignant progression of oesophageal cancer by targeting CDCA8.
Autorzy:
Wang X; Department of Thoracic Surgery, Nanyang Central Hospital, Guongnong Road, Nanyang City, Henan Province 473006, China.
Zhu L; Department of Thoracic Surgery, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, 134 East Street, Gulou District, Fuzhou City, Fujian Province 350001, China.
Lin X; Department of Thoracic Surgery, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, 134 East Street, Gulou District, Fuzhou City, Fujian Province 350001, China.
Huang Y; Department of Thoracic Surgery, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, 134 East Street, Gulou District, Fuzhou City, Fujian Province 350001, China.
Lin Z; Department of Thoracic Surgery, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, 134 East Street, Gulou District, Fuzhou City, Fujian Province 350001, China.
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Źródło:
Journal of biochemistry [J Biochem] 2022 Jan 07; Vol. 170 (6), pp. 689-698.
Typ publikacji:
Journal Article
MeSH Terms:
Cell Proliferation*
Cell Cycle Proteins/*metabolism
Esophageal Neoplasms/*metabolism
MicroRNAs/*metabolism
Neoplasm Proteins/*metabolism
RNA, Neoplasm/*metabolism
Cell Cycle Proteins/genetics ; Cell Line, Tumor ; Esophageal Neoplasms/genetics ; Humans ; MicroRNAs/genetics ; Neoplasm Proteins/genetics ; RNA, Neoplasm/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Hsa_circ_0000527 Downregulation Suppresses the Development of Retinoblastoma by Modulating the miR-27a-3p/HDAC9 Pathway.
Autorzy:
Zuo X; Department of Ophthalmology, Xingtai People's Hospital, Xingtai, Hebei, China.
Fu C; Department of Cardiac Surgery, Xingtai Third Hospital, Xingtai, Hebei, China.
Xie J; Department of Ophthalmology, Xingtai People's Hospital, Xingtai, Hebei, China.
Wang X; Department of Ophthalmology, Xingtai People's Hospital, Xingtai, Hebei, China.
Yan Z; Department of Ophthalmology, Xingtai People's Hospital, Xingtai, Hebei, China.
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Źródło:
Current eye research [Curr Eye Res] 2022 Jan; Vol. 47 (1), pp. 115-126. Date of Electronic Publication: 2021 Nov 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation, Neoplastic*
Apoptosis/*genetics
Histone Deacetylases/*genetics
MicroRNAs/*genetics
RNA, Neoplasm/*genetics
Repressor Proteins/*genetics
Retinal Neoplasms/*genetics
Retinoblastoma/*genetics
Animals ; Cell Line ; Cell Movement ; Cell Proliferation ; Cell Survival ; Down-Regulation ; Female ; Histone Deacetylases/biosynthesis ; Humans ; Mice ; Mice, Inbred BALB C ; MicroRNAs/biosynthesis ; RNA, Neoplasm/metabolism ; Repressor Proteins/biosynthesis ; Retinal Neoplasms/diagnosis ; Retinal Neoplasms/metabolism ; Retinoblastoma/diagnosis ; Retinoblastoma/metabolism
Czasopismo naukowe
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Tytuł:
LINC02532 Contributes to Radiosensitivity in Clear Cell Renal Cell Carcinoma through the miR-654-5p/YY1 Axis.
Autorzy:
Zhou X; Department of Urology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China.
Zeng B; Department of Urology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China.; Department of Urology, Affiliated Hospital of Sergeant School of Army Medical University, Shijiazhuang 050044, China.
Li Y; Department of Urology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China.
Wang H; Department of Urology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China.
Zhang X; Department of Urology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 Nov 22; Vol. 26 (22). Date of Electronic Publication: 2021 Nov 22.
Typ publikacji:
Journal Article
MeSH Terms:
Radiation Tolerance*
Carcinoma, Renal Cell/*metabolism
Kidney Neoplasms/*metabolism
MicroRNAs/*metabolism
Neoplasm Proteins/*metabolism
RNA, Long Noncoding/*metabolism
RNA, Neoplasm/*metabolism
YY1 Transcription Factor/*metabolism
Carcinoma, Renal Cell/genetics ; Carcinoma, Renal Cell/radiotherapy ; Cell Line, Tumor ; Humans ; Kidney Neoplasms/genetics ; Kidney Neoplasms/radiotherapy ; MicroRNAs/genetics ; Neoplasm Proteins/genetics ; RNA, Long Noncoding/genetics ; RNA, Neoplasm/genetics ; YY1 Transcription Factor/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Characterization of normal and cancer stem-like cell populations in murine lingual epithelial organoids using single-cell RNA sequencing.
Autorzy:
Johansson E; Department of Stem Cell Pathology, Kansai Medical University, 2-5-1 Shin-machi, Hirakata, Osaka, 573-1010, Japan.; CREST, Japan Science and Technology Agency, 4-1-8 Honcho, Kawaguchi, Saitama, 332-0012, Japan.
Ueno H; Department of Stem Cell Pathology, Kansai Medical University, 2-5-1 Shin-machi, Hirakata, Osaka, 573-1010, Japan. .; CREST, Japan Science and Technology Agency, 4-1-8 Honcho, Kawaguchi, Saitama, 332-0012, Japan. .
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Źródło:
Scientific reports [Sci Rep] 2021 Nov 16; Vol. 11 (1), pp. 22329. Date of Electronic Publication: 2021 Nov 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
RNA-Seq*
Single-Cell Analysis*
Neoplastic Stem Cells/*metabolism
Organoids/*metabolism
RNA, Neoplasm/*metabolism
Tongue Neoplasms/*metabolism
Animals ; Mice ; Mice, Transgenic ; Neoplasm Proteins/genetics ; Neoplasm Proteins/metabolism ; Neoplastic Stem Cells/pathology ; Organoids/pathology ; RNA, Neoplasm/genetics ; Tongue Neoplasms/genetics ; Tongue Neoplasms/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Therapeutic Targeting of Alternative RNA Splicing in Gastrointestinal Malignancies and Other Cancers.
Autorzy:
Sahin I; Division of Hematology Oncology, Department of Medicine, University of Florida Health Cancer Center, Gainesville, FL 32610, USA.
George A; Department of Chemistry, Brown University, Providence, RI 02912, USA.; Department of Molecular Biology, Cell Biology & Biochemistry, Division of Biology and Medicine, Brown University, Providence, RI 02912, USA.
Seyhan AA; Laboratory of Translational Oncology and Experimental Cancer Therapeutics, Warren Alpert Medical School, Brown University, Providence, RI 02912, USA.; The Joint Program in Cancer Biology, Brown University and Lifespan Health System, Providence, RI 02912, USA.; Cancer Center at Brown University, Warren Alpert Medical School, Brown University, Providence, RI 02912, USA.; Department of Pathology and Laboratory Medicine, Warren Alpert Medical School, Brown University, Providence, RI 02912, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Oct 30; Vol. 22 (21). Date of Electronic Publication: 2021 Oct 30.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Gastrointestinal Neoplasms*/drug therapy
Gastrointestinal Neoplasms*/genetics
Gastrointestinal Neoplasms*/metabolism
RNA Precursors*/biosynthesis
RNA Precursors*/genetics
RNA, Neoplasm*/genetics
RNA, Neoplasm*/metabolism
Alternative Splicing/*drug effects
Antineoplastic Agents/*therapeutic use
Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Long noncoding RNA landscapes specific to benign and malignant thyroid neoplasms of distinct histological subtypes.
Autorzy:
Yakushina VD; Research Centre for Medical Genetics, Moscow, Russia. .
Strelnikov VV; Research Centre for Medical Genetics, Moscow, Russia.
Tanas AS; Research Centre for Medical Genetics, Moscow, Russia.
Lavrov AV; Research Centre for Medical Genetics, Moscow, Russia.
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Źródło:
Scientific reports [Sci Rep] 2021 Aug 18; Vol. 11 (1), pp. 16728. Date of Electronic Publication: 2021 Aug 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Adenocarcinoma, Follicular*/genetics
Adenocarcinoma, Follicular*/metabolism
Adenoma*/genetics
Adenoma*/metabolism
RNA, Long Noncoding*/biosynthesis
RNA, Long Noncoding*/genetics
RNA, Neoplasm*/biosynthesis
RNA, Neoplasm*/genetics
Thyroid Cancer, Papillary*/genetics
Thyroid Cancer, Papillary*/metabolism
Thyroid Carcinoma, Anaplastic*/genetics
Thyroid Carcinoma, Anaplastic*/metabolism
Thyroid Neoplasms*/genetics
Thyroid Neoplasms*/metabolism
Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 2135

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