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Wyszukujesz frazę ""RNA, Transfer, Met"" wg kryterium: Temat


Tytuł:
The initiation factor 3 (IF3) residues interacting with initiator tRNA elbow modulate the fidelity of translation initiation and growth fitness in Escherichia coli.
Autorzy:
Singh J; Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore 560012, India.
Mishra RK; Department of Molecular Reproduction, Development and Genetics, Indian Institute of Science, Bangalore 560012, India.
Ayyub SA; Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore 560012, India.
Hussain T; Department of Molecular Reproduction, Development and Genetics, Indian Institute of Science, Bangalore 560012, India.
Varshney U; Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore 560012, India.; Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore 560064, India.
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2022 Nov 11; Vol. 50 (20), pp. 11712-11726.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Escherichia coli*/metabolism
RNA, Transfer, Met*/genetics
RNA, Transfer, Met*/metabolism
Escherichia coli Proteins*
Elbow ; Peptide Initiation Factors/metabolism ; Prokaryotic Initiation Factor-3/metabolism
Czasopismo naukowe
Tytuł:
eIF5B and eIF1A reorient initiator tRNA to allow ribosomal subunit joining.
Autorzy:
Lapointe CP; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, USA.
Grosely R; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, USA.
Sokabe M; Department of Molecular and Cellular Biology College of Biological Sciences, University of California, Davis, CA, USA.
Alvarado C; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, USA.
Wang J; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, USA.
Montabana E; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, USA.
Villa N; Department of Molecular and Cellular Biology College of Biological Sciences, University of California, Davis, CA, USA.
Shin BS; Section on Protein Biosynthesis, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.
Dever TE; Section on Protein Biosynthesis, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.
Fraser CS; Department of Molecular and Cellular Biology College of Biological Sciences, University of California, Davis, CA, USA.
Fernández IS; Department of Structural Biology, St Jude Children's Research Hospital, Memphis, TN, USA. .
Puglisi JD; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, USA. .
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Źródło:
Nature [Nature] 2022 Jul; Vol. 607 (7917), pp. 185-190. Date of Electronic Publication: 2022 Jun 22.
Typ publikacji:
Journal Article
MeSH Terms:
Eukaryotic Initiation Factor-1*/metabolism
Eukaryotic Initiation Factors*/genetics
RNA, Transfer, Met*/genetics
RNA, Transfer, Met*/metabolism
Ribosome Subunits*/chemistry
Ribosome Subunits*/metabolism
Cryoelectron Microscopy ; Humans ; Single Molecule Imaging
Czasopismo naukowe
Tytuł:
Compact IF2 allows initiator tRNA accommodation into the P site and gates the ribosome to elongation.
Autorzy:
Basu RS; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, 77555, USA.
Sherman MB; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX, 77555, USA.; Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch, Galveston, TX, 77555, USA.
Gagnon MG; Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, 77555, USA. .; Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX, 77555, USA. .; Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch, Galveston, TX, 77555, USA. .; Institute for Human Infections and Immunity, University of Texas Medical Branch, Galveston, TX, 77555, USA. .
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Źródło:
Nature communications [Nat Commun] 2022 Jun 13; Vol. 13 (1), pp. 3388. Date of Electronic Publication: 2022 Jun 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Prokaryotic Initiation Factor-2*/chemistry
RNA, Transfer, Met*/metabolism
Cryoelectron Microscopy ; Guanosine Triphosphate/metabolism ; Ribosomes/metabolism
Czasopismo naukowe
Tytuł:
Systematic evolution of initiation factor 3 and the ribosomal protein uS12 optimizes Escherichia coli growth with an unconventional initiator tRNA.
Autorzy:
Datta M; Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, India.
Singh J; Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, India.
Modak MJ; Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, India.
Pillai M; Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, India.
Varshney U; Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, India.; Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore, India.
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Źródło:
Molecular microbiology [Mol Microbiol] 2022 Feb; Vol. 117 (2), pp. 462-479. Date of Electronic Publication: 2021 Dec 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Escherichia coli*/metabolism
RNA, Transfer, Met*/genetics
RNA, Transfer, Met*/metabolism
Peptide Chain Initiation, Translational/genetics ; Prokaryotic Initiation Factor-3/metabolism ; Protein Subunits ; Ribosomal Proteins/genetics ; Ribosomal Proteins/metabolism
Czasopismo naukowe
Tytuł:
Utilisation of a mitochondrial intergenic region for species differentiation of fruit flies (Diptera: Tephritidae) in South Africa.
Autorzy:
Andrews KJ; Department of Genetics, Stellenbosch University, Private Bag X1, 7602, Matieland, South Africa.
Bester R; Department of Genetics, Stellenbosch University, Private Bag X1, 7602, Matieland, South Africa.; Citrus Research International, PO Box 2201, 7602, Matieland, South Africa.
Manrakhan A; Citrus Research International, PO Box 28, 1200, Mbombela, South Africa.; Department of Conservation Ecology and Entomology, Stellenbosch University, Private Bag X1, 7602, Matieland, South Africa.
Maree HJ; Department of Genetics, Stellenbosch University, Private Bag X1, 7602, Matieland, South Africa. .; Citrus Research International, PO Box 2201, 7602, Matieland, South Africa. .
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Źródło:
BMC genomics [BMC Genomics] 2022 Dec 01; Vol. 23 (1), pp. 793. Date of Electronic Publication: 2022 Dec 01.
Typ publikacji:
Journal Article
MeSH Terms:
Tephritidae*/genetics
Male ; Animals ; DNA, Intergenic/genetics ; RNA, Transfer, Gln ; South Africa ; RNA, Transfer, Ile ; RNA, Transfer, Met ; Drosophila
Czasopismo naukowe
Tytuł:
Synthesis and properties of the anticodon stem-loop of human mitochondrial tRNA G nucleosides at position 37.
Autorzy:
Podskoczyj K; Institute of Organic Chemistry, Faculty of Chemistry, Lodz University of Technology, Zeromskiego 116, Lodz 90-924, Poland. .
Kulik K; Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Division of Bioorganic Chemistry, Sienkiewicza 112, Lodz 90-363, Poland.
Wasko J; Institute of Organic Chemistry, Faculty of Chemistry, Lodz University of Technology, Zeromskiego 116, Lodz 90-924, Poland. .
Nawrot B; Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Division of Bioorganic Chemistry, Sienkiewicza 112, Lodz 90-363, Poland.
Suzuki T; Department of Chemistry and Biotechnology, Graduate School of Engineering, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8656, Japan.
Leszczynska G; Institute of Organic Chemistry, Faculty of Chemistry, Lodz University of Technology, Zeromskiego 116, Lodz 90-924, Poland. .
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Źródło:
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2021 Nov 23; Vol. 57 (93), pp. 12540-12543. Date of Electronic Publication: 2021 Nov 23.
Typ publikacji:
Journal Article
MeSH Terms:
Guanosine/*analogs & derivatives
Guanosine/*chemistry
Mitochondria/*metabolism
RNA, Transfer, Met/*genetics
Codon ; Diabetes Mellitus, Type 2/genetics ; Diabetes Mellitus, Type 2/pathology ; Humans ; Hypertension/genetics ; Hypertension/pathology ; Nucleic Acid Conformation ; Optic Atrophy, Hereditary, Leber/genetics ; Optic Atrophy, Hereditary, Leber/pathology ; RNA, Transfer, Met/chemistry
Czasopismo naukowe
Tytuł:
Microevolution of CG23-I Hypervirulent Klebsiella pneumoniae during Recurrent Infections in a Single Patient.
Autorzy:
Wang YC; Department of Internal Medicine, Chung Shan Medical Universitygrid.411641.7 Hospital, Taichung, Taiwan.; School of Medicine, Chung Shan Medical Universitygrid.411641.7, Taichung, Taiwan.
Lu MC; Department of Microbiology and Immunology, School of Medicine, China Medical Universitygrid.411508.9grid.254145.3, Taichung, Taiwan.; Division of Infectious Diseases, Department of Internal Medicine, China Medical University Hospitalgrid.411508.9, Taichung, Taiwan.
Li YT; Division of Respiratory Therapy, Department of Internal Medicine, Chung Shan Medical Universitygrid.411641.7 Hospital, Taichung, Taiwan.
Tang HL; Department of Microbiology and Immunology, School of Medicine, China Medical Universitygrid.411508.9grid.254145.3, Taichung, Taiwan.
Hsiao PY; Department of Microbiology and Immunology, School of Medicine, Chung Shan Medical Universitygrid.411641.7, Taichung, Taiwan.
Chen BH; Central Region Laboratory, Center for Diagnostics and Vaccine Development, Centers for Disease Control, Ministry of Health and Welfare, Taipei, Taiwan.
Teng RH; Central Region Laboratory, Center for Diagnostics and Vaccine Development, Centers for Disease Control, Ministry of Health and Welfare, Taipei, Taiwan.
Chiou CS; Central Region Laboratory, Center for Diagnostics and Vaccine Development, Centers for Disease Control, Ministry of Health and Welfare, Taipei, Taiwan.
Lai YC; Department of Internal Medicine, Chung Shan Medical Universitygrid.411641.7 Hospital, Taichung, Taiwan.; Department of Microbiology and Immunology, School of Medicine, Chung Shan Medical Universitygrid.411641.7, Taichung, Taiwan.
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Źródło:
Microbiology spectrum [Microbiol Spectr] 2022 Oct 26; Vol. 10 (5), pp. e0207722. Date of Electronic Publication: 2022 Sep 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Klebsiella pneumoniae*/genetics
Klebsiella Infections*/epidemiology
Klebsiella Infections*/genetics
Klebsiella Infections*/microbiology
Mice ; Animals ; Humans ; RNA, Transfer, Met ; Reinfection ; RNA, Transfer, Arg ; Genome, Bacterial/genetics ; Plasmids ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use
Czasopismo naukowe
Tytuł:
Human TRUB1 is a highly conserved pseudouridine synthase responsible for the formation of Ψ55 in mitochondrial tRNAAsn, tRNAGln, tRNAGlu and tRNAPro.
Autorzy:
Jia Z; Division of Medical Genetics and Genomics, The Children's Hospital, Zhejiang University School of Medicine and National Clinical Research Center for Child Health, Hangzhou, Zhejiang, China.; Institute of Genetics, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Meng F; Division of Medical Genetics and Genomics, The Children's Hospital, Zhejiang University School of Medicine and National Clinical Research Center for Child Health, Hangzhou, Zhejiang, China.; Institute of Genetics, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Chen H; Institute of Genetics, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Zhu G; Institute of Genetics, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Li X; Institute of Genetics, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
He Y; Institute of Genetics, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Zhang L; Institute of Genetics, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
He X; Institute of Genetics, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Zhan H; Institute of Genetics, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Chen M; Department of Lab Medicine, Wenzhou Hospital of Traditional Chinese Medicine, Wenzhou, Zhejiang, China.
Ji Y; Division of Medical Genetics and Genomics, The Children's Hospital, Zhejiang University School of Medicine and National Clinical Research Center for Child Health, Hangzhou, Zhejiang, China.; Institute of Genetics, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Wang M; Division of Medical Genetics and Genomics, The Children's Hospital, Zhejiang University School of Medicine and National Clinical Research Center for Child Health, Hangzhou, Zhejiang, China.; Institute of Genetics, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Guan MX; Division of Medical Genetics and Genomics, The Children's Hospital, Zhejiang University School of Medicine and National Clinical Research Center for Child Health, Hangzhou, Zhejiang, China.; Institute of Genetics, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.; Zhejiang Provincial Key Laboratory of Genetic and Developmental Disorders, Hangzhou, Zhejiang, China.; Joint Institute of Genetics and Genome Medicine between Zhejiang University and University of Toronto, Hangzhou, Zhejiang, China.
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2022 Sep 09; Vol. 50 (16), pp. 9368-9381.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
RNA, Transfer, Glu*
Intramolecular Transferases*/genetics
Intramolecular Transferases*/metabolism
Animals ; Humans ; RNA, Transfer, Gln ; RNA, Transfer, Pro ; RNA, Transfer, Asn ; RNA, Transfer, Met ; HeLa Cells ; Pseudouridine/genetics ; Pseudouridine/metabolism ; RNA, Transfer/metabolism ; Mammals/genetics
Czasopismo naukowe
Tytuł:
Initiator tRNA lacking 1-methyladenosine is targeted by the rapid tRNA decay pathway in evolutionarily distant yeast species.
Autorzy:
Tasak M; Department of Biochemistry and Biophysics, Center for RNA Biology, University of Rochester School of Medicine, Rochester, New York, United States of America.
Phizicky EM; Department of Biochemistry and Biophysics, Center for RNA Biology, University of Rochester School of Medicine, Rochester, New York, United States of America.
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Źródło:
PLoS genetics [PLoS Genet] 2022 Jul 28; Vol. 18 (7), pp. e1010215. Date of Electronic Publication: 2022 Jul 28 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Saccharomyces cerevisiae Proteins*/genetics
Saccharomyces cerevisiae Proteins*/metabolism
Schizosaccharomyces*/genetics
Schizosaccharomyces*/metabolism
Adenosine/analogs & derivatives ; Exonucleases/genetics ; Exoribonucleases/genetics ; Exoribonucleases/metabolism ; Humans ; Phylogeny ; RNA, Transfer/genetics ; RNA, Transfer/metabolism ; RNA, Transfer, Met/genetics ; RNA, Transfer, Met/metabolism ; Saccharomyces cerevisiae/metabolism
Czasopismo naukowe
Tytuł:
Mitochondrial RNA modifications shape metabolic plasticity in metastasis.
Autorzy:
Delaunay S; German Cancer Research Center - Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany.
Pascual G; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.
Feng B; Department of Otolaryngology, Head and Neck Surgery, University Hospital Heidelberg, Heidelberg, Germany.; Department of Otorhinolaryngology, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.
Klann K; Institute of Biochemistry II, University Hospital, Goethe University Frankfurt, Frankfurt am Main, Germany.
Behm M; German Cancer Research Center - Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany.
Hotz-Wagenblatt A; German Cancer Research Center - Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany.
Richter K; German Cancer Research Center - Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany.
Zaoui K; Department of Otolaryngology, Head and Neck Surgery, University Hospital Heidelberg, Heidelberg, Germany.
Herpel E; Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.; NCT Tissue Bank, National Center for Tumor Diseases (NCT), Heidelberg, Germany.
Münch C; Institute of Biochemistry II, University Hospital, Goethe University Frankfurt, Frankfurt am Main, Germany.
Dietmann S; Washington University School of Medicine in St. Louis, St. Louis, MO, USA.
Hess J; German Cancer Research Center - Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany.; Department of Otolaryngology, Head and Neck Surgery, University Hospital Heidelberg, Heidelberg, Germany.
Benitah SA; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.; Catalan Institution for Research and Advanced Studies (ICREA), Barcelona, Spain.
Frye M; German Cancer Research Center - Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany. .
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Źródło:
Nature [Nature] 2022 Jul; Vol. 607 (7919), pp. 593-603. Date of Electronic Publication: 2022 Jun 29.
Typ publikacji:
Journal Article
MeSH Terms:
5-Methylcytosine*/biosynthesis
5-Methylcytosine*/metabolism
Glycolysis*/drug effects
Mitochondria*/drug effects
Mitochondria*/genetics
Mitochondria*/metabolism
Neoplasm Metastasis*/drug therapy
Neoplasm Metastasis*/genetics
Neoplasm Metastasis*/pathology
Oxidative Phosphorylation*/drug effects
RNA, Mitochondrial*/genetics
RNA, Mitochondrial*/metabolism
Cytosine/*analogs & derivatives
CD36 Antigens ; Cell Survival ; Cytosine/metabolism ; Disease Progression ; Humans ; Methylation/drug effects ; Methyltransferases/antagonists & inhibitors ; Methyltransferases/metabolism ; Mouth Neoplasms/genetics ; Mouth Neoplasms/metabolism ; Mouth Neoplasms/pathology ; Protein Biosynthesis/drug effects ; RNA, Transfer, Met/genetics ; RNA, Transfer, Met/metabolism
Czasopismo naukowe
Tytuł:
An Alternative Role of RluD in the Fidelity of Translation Initiation in Escherichia coli.
Autorzy:
Lahry K; Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore 560012, India. Electronic address: https://twitter.com/kdlahry.
Gopal A; Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore 560012, India. Electronic address: https://twitter.com/gopal_aiswarya.
Sahu AK; Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore 560012, India. Electronic address: https://twitter.com/sahuamit12.
Marbaniang CN; Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore 560012, India.
Shah RA; Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore 560012, India. Electronic address: https://twitter.com/Ribo_riyaz.
Mehta A; Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore 560012, India.
Varshney U; Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore 560012, India; Jawaharlal Nehru Centre for Advanced Scientific Research, Jakkur, Bangalore 560064, India. Electronic address: .
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Źródło:
Journal of molecular biology [J Mol Biol] 2022 Jun 30; Vol. 434 (12), pp. 167588. Date of Electronic Publication: 2022 Apr 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Escherichia coli*/genetics
Escherichia coli*/metabolism
Escherichia coli Proteins*/genetics
Escherichia coli Proteins*/metabolism
Peptide Chain Initiation, Translational*
Ribosomal Proteins*/genetics
Ribosomal Proteins*/metabolism
Anticodon/genetics ; Anticodon/metabolism ; Hydro-Lyases/chemistry ; Mutation ; Pseudouridine/biosynthesis ; RNA, Transfer, Met/genetics ; RNA, Transfer, Met/metabolism
Czasopismo naukowe
Tytuł:
Role of aIF5B in archaeal translation initiation.
Autorzy:
Kazan R; Laboratoire de Biologie Structurale de la Cellule, BIOC, Ecole polytechnique, CNRS, Institut Polytechnique de Paris, 91128 Palaiseau cedex, France.
Bourgeois G; Laboratoire de Biologie Structurale de la Cellule, BIOC, Ecole polytechnique, CNRS, Institut Polytechnique de Paris, 91128 Palaiseau cedex, France.
Lazennec-Schurdevin C; Laboratoire de Biologie Structurale de la Cellule, BIOC, Ecole polytechnique, CNRS, Institut Polytechnique de Paris, 91128 Palaiseau cedex, France.
Larquet E; Laboratoire de Physique de la Matière Condensée, PMC, Ecole polytechnique, CNRS, Institut Polytechnique de Paris, 91128 Palaiseau cedex, France.
Mechulam Y; Laboratoire de Biologie Structurale de la Cellule, BIOC, Ecole polytechnique, CNRS, Institut Polytechnique de Paris, 91128 Palaiseau cedex, France.
Coureux PD; Laboratoire de Biologie Structurale de la Cellule, BIOC, Ecole polytechnique, CNRS, Institut Polytechnique de Paris, 91128 Palaiseau cedex, France.
Schmitt E; Laboratoire de Biologie Structurale de la Cellule, BIOC, Ecole polytechnique, CNRS, Institut Polytechnique de Paris, 91128 Palaiseau cedex, France.
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2022 Jun 24; Vol. 50 (11), pp. 6532-6548.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Archaea*/genetics
Eukaryotic Initiation Factors*/metabolism
Guanosine Triphosphate/metabolism ; Peptide Initiation Factors/genetics ; Peptide Initiation Factors/metabolism ; RNA, Transfer, Met/metabolism ; Ribosomes/metabolism
Czasopismo naukowe
Tytuł:
A SAM-I riboswitch with the ability to sense and respond to uncharged initiator tRNA.
Autorzy:
Tang DJ; State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, College of Life Science and Technology, Guangxi University, Guangxi, China.
Du X; Shanghai Key Laboratory of Medical Epigenetics, the International Co-laboratory of Medical Epigenetics and Metabolism, Ministry of Science and Technology, Institutes of Biomedical Sciences, Fudan University, Shanghai, China.; Center for Medical Research and Innovation, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, Shanghai, China.
Shi Q; Endoscopy Center, Zhongshan Hospital of Fudan University, Shanghai, China.
Zhang JL; State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, College of Life Science and Technology, Guangxi University, Guangxi, China.; School of Public Health, Zunyi Medical University, 563000, Zunyi, Guizhou, China.
He YP; State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, College of Life Science and Technology, Guangxi University, Guangxi, China.
Chen YM; State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, College of Life Science and Technology, Guangxi University, Guangxi, China.
Ming Z; State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, College of Life Science and Technology, Guangxi University, Guangxi, China.
Wang D; State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, College of Life Science and Technology, Guangxi University, Guangxi, China.
Zhong WY; State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, College of Life Science and Technology, Guangxi University, Guangxi, China.
Liang YW; State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, College of Life Science and Technology, Guangxi University, Guangxi, China.
Liu JY; State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, College of Life Science and Technology, Guangxi University, Guangxi, China.
Huang JM; Center for Medical Research and Innovation, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, Shanghai, China.
Zhong YS; Endoscopy Center, Zhongshan Hospital of Fudan University, Shanghai, China.
An SQ; National Biofilms Innovation Centre (NBIC), Biological Sciences, University of Southampton, University Road, Southampton, SO17 1BJ, UK.
Gu H; Shanghai Key Laboratory of Medical Epigenetics, the International Co-laboratory of Medical Epigenetics and Metabolism, Ministry of Science and Technology, Institutes of Biomedical Sciences, Fudan University, Shanghai, China. .; Center for Medical Research and Innovation, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, Shanghai, China. .; Endoscopy Center, Zhongshan Hospital of Fudan University, Shanghai, China. .
Tang JL; State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources, College of Life Science and Technology, Guangxi University, Guangxi, China. .
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Źródło:
Nature communications [Nat Commun] 2020 Jun 03; Vol. 11 (1), pp. 2794. Date of Electronic Publication: 2020 Jun 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Riboswitch*
RNA, Transfer, Met/*metabolism
S-Adenosylmethionine/*metabolism
Base Sequence ; Genetic Loci ; Models, Biological ; Nucleic Acid Conformation ; Operon/genetics ; Protein Biosynthesis ; RNA, Transfer, Met/chemistry ; RNA, Transfer, Met/genetics
Czasopismo naukowe
Tytuł:
Commonality and diversity in tRNA substrate recognition in t6A biogenesis by eukaryotic KEOPSs.
Autorzy:
Wang JT; State Key Laboratory of Molecular Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, 320 Yue Yang Road, Shanghai 200031, China.
Zhou JB; State Key Laboratory of Molecular Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, 320 Yue Yang Road, Shanghai 200031, China.
Mao XL; State Key Laboratory of Molecular Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, 320 Yue Yang Road, Shanghai 200031, China.
Zhou L; School of Life Sciences, Lanzhou University, 222 South Tianshui Road, Lanzhou 730000, Gansu.
Chen M; School of Pharmacy, China Pharmaceutical University, 639 Longmian Avenue, Nanjing 211198, Jiangsu.
Zhang W; School of Life Sciences, Lanzhou University, 222 South Tianshui Road, Lanzhou 730000, Gansu.
Wang ED; State Key Laboratory of Molecular Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, 320 Yue Yang Road, Shanghai 200031, China.; School of Life Science and Technology, ShanghaiTech University, 393 Middle Hua Xia Road, Shanghai 201210, China.
Zhou XL; State Key Laboratory of Molecular Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, 320 Yue Yang Road, Shanghai 200031, China.
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2022 Feb 28; Vol. 50 (4), pp. 2223-2239.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Eukaryota*/genetics
RNA, Transfer, Ile*
Adenosine/genetics ; Animals ; Codon ; HEK293 Cells ; Humans ; Mammals/genetics ; Nucleic Acid Conformation ; RNA, Transfer/genetics ; RNA, Transfer, Met
Czasopismo naukowe
Tytuł:
Stepwise assembly of the eukaryotic translation initiation factor 2 complex.
Autorzy:
Vanselow S; Department of Genetics, Regensburg Center for Biochemistry, University of Regensburg, Regensburg, Germany.
Neumann-Arnold L; Department of Genetics, Regensburg Center for Biochemistry, University of Regensburg, Regensburg, Germany.
Wojciech-Moock F; Department of Genetics, Regensburg Center for Biochemistry, University of Regensburg, Regensburg, Germany.
Seufert W; Department of Genetics, Regensburg Center for Biochemistry, University of Regensburg, Regensburg, Germany. Electronic address: .
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Źródło:
The Journal of biological chemistry [J Biol Chem] 2022 Feb; Vol. 298 (2), pp. 101583. Date of Electronic Publication: 2022 Jan 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Eukaryotic Initiation Factor-2*/genetics
Eukaryotic Initiation Factor-2*/metabolism
Prokaryotic Initiation Factor-2*/metabolism
Cell Cycle Proteins/genetics ; Cell Cycle Proteins/metabolism ; Eukaryotic Initiation Factor-2B/chemistry ; Eukaryotic Initiation Factor-2B/genetics ; Eukaryotic Initiation Factor-2B/metabolism ; Eukaryotic Initiation Factor-5/metabolism ; Humans ; RNA, Transfer, Met/metabolism ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism ; Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/metabolism
Czasopismo naukowe
Tytuł:
Weakening the IF2-fMet-tRNA Interaction Suppresses the Lethal Phenotype Caused by GTPase Inactivation.
Autorzy:
Tomsic J; Laboratory of Genetics, Department of Bioscience and Biotechnology, University of Camerino, 62032 Camerino, Italy.; City of Hope Comprehensive Cancer Center, Duarte, CA 91010, USA.
Caserta E; Laboratory of Genetics, Department of Bioscience and Biotechnology, University of Camerino, 62032 Camerino, Italy.; City of Hope Comprehensive Cancer Center, Duarte, CA 91010, USA.
Pon CL; Laboratory of Genetics, Department of Bioscience and Biotechnology, University of Camerino, 62032 Camerino, Italy.
Gualerzi CO; Laboratory of Genetics, Department of Bioscience and Biotechnology, University of Camerino, 62032 Camerino, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Dec 08; Vol. 22 (24). Date of Electronic Publication: 2021 Dec 08.
Typ publikacji:
Journal Article
MeSH Terms:
Genes, Lethal*
Escherichia coli/*growth & development
GTP Phosphohydrolases/*metabolism
Prokaryotic Initiation Factor-2/*chemistry
Prokaryotic Initiation Factor-2/*metabolism
RNA, Transfer, Met/*metabolism
Escherichia coli/genetics ; Escherichia coli/metabolism ; Escherichia coli Proteins/chemistry ; Escherichia coli Proteins/genetics ; Escherichia coli Proteins/metabolism ; Guanosine Triphosphate/chemistry ; Hydrolysis ; Models, Molecular ; Phenotype ; Prokaryotic Initiation Factor-2/genetics ; Protein Conformation ; Protein Domains ; Ribosomes/chemistry ; Ribosomes/metabolism
Czasopismo naukowe
Tytuł:
A novel pathogenic m.4412G>A MT-TM mitochondrial DNA variant associated with childhood-onset seizures, myopathy and bilateral basal ganglia changes.
Autorzy:
Lim AZ; Wellcome Centre for Mitochondrial Research, Institute of Neuroscience, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
Blakely EL; Wellcome Centre for Mitochondrial Research, Institute of Neuroscience, Newcastle University, Newcastle upon Tyne NE2 4HH, UK; NHS Highly Specialised Service for Rare Mitochondrial Disorders of Adults and Children, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne NE2 4HH, UK.
Baty K; Wellcome Centre for Mitochondrial Research, Institute of Neuroscience, Newcastle University, Newcastle upon Tyne NE2 4HH, UK; NHS Highly Specialised Service for Rare Mitochondrial Disorders of Adults and Children, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne NE2 4HH, UK.
He L; Wellcome Centre for Mitochondrial Research, Institute of Neuroscience, Newcastle University, Newcastle upon Tyne NE2 4HH, UK; NHS Highly Specialised Service for Rare Mitochondrial Disorders of Adults and Children, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne NE2 4HH, UK.
Hopton S; Wellcome Centre for Mitochondrial Research, Institute of Neuroscience, Newcastle University, Newcastle upon Tyne NE2 4HH, UK; NHS Highly Specialised Service for Rare Mitochondrial Disorders of Adults and Children, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne NE2 4HH, UK.
Falkous G; Wellcome Centre for Mitochondrial Research, Institute of Neuroscience, Newcastle University, Newcastle upon Tyne NE2 4HH, UK; NHS Highly Specialised Service for Rare Mitochondrial Disorders of Adults and Children, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne NE2 4HH, UK.
McWilliam K; Department of Paediatric Neurology, Royal Hospital for Sick Children, Edinburgh EH9 1LF, UK.
Cozens A; Inherited Metabolic Disorders Scotland, NHS National Services Scotland, Glasgow G2 6QE, UK.
McFarland R; Wellcome Centre for Mitochondrial Research, Institute of Neuroscience, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
Taylor RW; Wellcome Centre for Mitochondrial Research, Institute of Neuroscience, Newcastle University, Newcastle upon Tyne NE2 4HH, UK; NHS Highly Specialised Service for Rare Mitochondrial Disorders of Adults and Children, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne NE2 4HH, UK. Electronic address: .
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Źródło:
Mitochondrion [Mitochondrion] 2019 Jul; Vol. 47, pp. 18-23. Date of Electronic Publication: 2019 Apr 22.
Typ publikacji:
Case Reports; Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Basal Ganglia*/metabolism
Basal Ganglia*/pathology
DNA, Mitochondrial*/genetics
DNA, Mitochondrial*/metabolism
Mitochondrial Myopathies*/genetics
Mitochondrial Myopathies*/metabolism
Mitochondrial Myopathies*/pathology
Mitochondrial Myopathies*/physiopathology
Point Mutation*
Seizures*/genetics
Seizures*/metabolism
Seizures*/pathology
Seizures*/physiopathology
RNA, Mitochondrial/*genetics
RNA, Transfer, Met/*genetics
Child ; Female ; Humans ; RNA, Mitochondrial/metabolism ; RNA, Transfer, Met/metabolism
Czasopismo naukowe
Tytuł:
The structural basis of translational control by eIF2 phosphorylation.
Autorzy:
Adomavicius T; Division of Molecular and Cellular Function, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester, M13 9PT, UK.
Guaita M; Division of Molecular and Cellular Function, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester, M13 9PT, UK.
Zhou Y; Division of Molecular and Cellular Function, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester, M13 9PT, UK.; The Jenner Institute, Old Road Campus Research Building Roosevelt Drive, Oxford, OX3 7DQ, UK.
Jennings MD; Division of Molecular and Cellular Function, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester, M13 9PT, UK.
Latif Z; Division of Molecular and Cellular Function, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester, M13 9PT, UK.; Department of Microbiology and Molecular Genetics, University of the Punjab, Lahore, Pakistan.
Roseman AM; Division of Molecular and Cellular Function, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester, M13 9PT, UK. .
Pavitt GD; Division of Molecular and Cellular Function, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester, M13 9PT, UK. .
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Źródło:
Nature communications [Nat Commun] 2019 May 13; Vol. 10 (1), pp. 2136. Date of Electronic Publication: 2019 May 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Eukaryotic Initiation Factor-2/*ultrastructure
Eukaryotic Initiation Factor-2B/*ultrastructure
RNA, Transfer, Met/*ultrastructure
Saccharomyces cerevisiae Proteins/*ultrastructure
Computer Simulation ; Cryoelectron Microscopy ; Eukaryotic Initiation Factor-2/metabolism ; Eukaryotic Initiation Factor-2B/metabolism ; Models, Molecular ; Nucleotides/metabolism ; Phosphorylation/physiology ; Protein Binding/physiology ; Protein Biosynthesis/physiology ; RNA, Transfer, Met/metabolism ; Saccharomyces cerevisiae Proteins/metabolism ; eIF-2 Kinase/metabolism
Czasopismo naukowe
Tytuł:
Msc6p is required for mitochondrial translation initiation in the absence of formylated Met-tRNA .
Autorzy:
Franco LVR; Departamento de Microbiologia - Instituto de Ciências Biomédicas, Universidade de São Paulo, Brazil.
Moda BS; Departamento de Microbiologia - Instituto de Ciências Biomédicas, Universidade de São Paulo, Brazil.
Soares MAKM; Departamento de Microbiologia - Instituto de Ciências Biomédicas, Universidade de São Paulo, Brazil.
Barros MH; Departamento de Microbiologia - Instituto de Ciências Biomédicas, Universidade de São Paulo, Brazil.
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Źródło:
The FEBS journal [FEBS J] 2019 Apr; Vol. 286 (7), pp. 1407-1419. Date of Electronic Publication: 2019 Mar 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Peptide Chain Initiation, Translational*
Protein Processing, Post-Translational*
RNA, Transfer, Met*
Mitochondria/*metabolism
RNA, Transfer/*metabolism
Saccharomyces cerevisiae/*metabolism
Saccharomyces cerevisiae Proteins/*metabolism
Eukaryotic Initiation Factors/genetics ; Eukaryotic Initiation Factors/metabolism ; Mitochondrial Proteins/genetics ; Mitochondrial Proteins/metabolism ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/growth & development ; Saccharomyces cerevisiae Proteins/genetics
Czasopismo naukowe
Tytuł:
Rapid formylation of the cellular initiator tRNA population makes a crucial contribution to its exclusive participation at the step of initiation.
Autorzy:
Shah RA; Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore 560012, India.
Varada R; Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore 560012, India.
Sah S; Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore 560012, India.
Shetty S; Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore 560012, India.
Lahry K; Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore 560012, India.
Singh S; Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore 560012, India.
Varshney U; Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore 560012, India.; Jawaharlal Nehru Centre for Advanced Scientific Research, Jakkur, Bangalore 560064, India.
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Źródło:
Nucleic acids research [Nucleic Acids Res] 2019 Feb 28; Vol. 47 (4), pp. 1908-1919.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Nucleic Acid Conformation*
Anticodon/*genetics
RNA, Transfer, Met/*chemistry
Ribosomes/*chemistry
Anticodon/chemistry ; Escherichia coli/chemistry ; Escherichia coli/genetics ; Plasmids/genetics ; RNA, Transfer, Met/genetics ; Ribosome Subunits, Small, Bacterial/chemistry ; Ribosome Subunits, Small, Bacterial/genetics ; Ribosomes/genetics
Czasopismo naukowe

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