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Wyszukujesz frazę ""RNA Interference"" wg kryterium: Temat


Tytuł :
RNA interference of mTOR gene delays molting process in Eriocheir sinensis.
Autorzy :
Hou X; Key Laboratory of Freshwater Aquatic Genetic Resources, Ministry of Agriculture/ National Demonstration Center for Experimental Fisheries Science Education / Shanghai Engineering Research Center of Aquaculture, Shanghai Ocean University, No.999, Huchenghuan Rd, Nanhui New City, Shanghai, PR China.
Yang H; Key Laboratory of Freshwater Aquatic Genetic Resources, Ministry of Agriculture/ National Demonstration Center for Experimental Fisheries Science Education / Shanghai Engineering Research Center of Aquaculture, Shanghai Ocean University, No.999, Huchenghuan Rd, Nanhui New City, Shanghai, PR China.
Chen X; Key Laboratory of Freshwater Aquatic Genetic Resources, Ministry of Agriculture/ National Demonstration Center for Experimental Fisheries Science Education / Shanghai Engineering Research Center of Aquaculture, Shanghai Ocean University, No.999, Huchenghuan Rd, Nanhui New City, Shanghai, PR China; Department of Pharmacy, School of Medicine, Tongji University, 1239 Siping Road, Shanghai, PR China.
Wang J; Key Laboratory of Freshwater Aquatic Genetic Resources, Ministry of Agriculture/ National Demonstration Center for Experimental Fisheries Science Education / Shanghai Engineering Research Center of Aquaculture, Shanghai Ocean University, No.999, Huchenghuan Rd, Nanhui New City, Shanghai, PR China. Electronic address: .
Wang C; Key Laboratory of Freshwater Aquatic Genetic Resources, Ministry of Agriculture/ National Demonstration Center for Experimental Fisheries Science Education / Shanghai Engineering Research Center of Aquaculture, Shanghai Ocean University, No.999, Huchenghuan Rd, Nanhui New City, Shanghai, PR China. Electronic address: .
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Źródło :
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology [Comp Biochem Physiol B Biochem Mol Biol] 2021 Oct-Dec; Vol. 256, pp. 110651. Date of Electronic Publication: 2021 Jul 25.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Developmental*
Molting*
RNA Interference*
RNA, Small Interfering/*genetics
TOR Serine-Threonine Kinases/*antagonists & inhibitors
Animals ; Brachyura ; Signal Transduction ; TOR Serine-Threonine Kinases/genetics ; TOR Serine-Threonine Kinases/metabolism
Czasopismo naukowe
Tytuł :
HOTAIR suppresses PTEN via DNMT3b and confers drug resistance in acute myeloid leukemia.
Autorzy :
Zhou W; Department of Hematology, School of Medicine, Guangzhou First People's Hospital, South China University of Technology, Guangzhou, People's Republic of China.
Xu S; Department of Hematology, School of Medicine, Guangzhou First People's Hospital, South China University of Technology, Guangzhou, People's Republic of China.
Chen X; Department of Hematology, School of Medicine, Guangzhou First People's Hospital, South China University of Technology, Guangzhou, People's Republic of China.
Wang C; Department of Hematology, School of Medicine, Guangzhou First People's Hospital, South China University of Technology, Guangzhou, People's Republic of China.
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Źródło :
Hematology (Amsterdam, Netherlands) [Hematology] 2021 Dec; Vol. 26 (1), pp. 170-178.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Leukemic*
RNA Interference*
DNA (Cytosine-5-)-Methyltransferases/*genetics
Drug Resistance, Neoplasm/*genetics
Leukemia, Myeloid, Acute/*genetics
PTEN Phosphohydrolase/*genetics
RNA, Long Noncoding/*genetics
Adult ; Aged ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Bone Marrow/metabolism ; Bone Marrow/pathology ; Bone Marrow Cells ; Cell Line, Tumor ; Female ; Gene Knockdown Techniques ; Humans ; Leukemia, Myeloid, Acute/diagnosis ; Leukemia, Myeloid, Acute/drug therapy ; Male ; Middle Aged ; Recurrence ; Young Adult
Czasopismo naukowe
Tytuł :
SIRT6 silencing overcomes resistance to sorafenib by promoting ferroptosis in gastric cancer.
Autorzy :
Cai S; Department of Anaesthesiology, The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Hangzhou, China.
Fu S; Department of Anaesthesiology, The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Hangzhou, China.
Zhang W; Department of Anaesthesiology, The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Hangzhou, China.
Yuan X; Department of Anaesthesiology, The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Hangzhou, China.
Cheng Y; Department of Anaesthesiology, The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Hangzhou, China.
Fang J; Department of Anaesthesiology, The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Hangzhou, China. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2021 Nov 05; Vol. 577, pp. 158-164. Date of Electronic Publication: 2021 Aug 30.
Typ publikacji :
Journal Article
MeSH Terms :
RNA Interference*
Drug Resistance, Neoplasm/*genetics
Ferroptosis/*genetics
Sirtuins/*genetics
Sorafenib/*pharmacology
Stomach Neoplasms/*genetics
Blotting, Western ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Proliferation/genetics ; Cell Survival/drug effects ; Cell Survival/genetics ; Drug Resistance, Neoplasm/drug effects ; Ferroptosis/drug effects ; Gene Expression Regulation, Neoplastic ; Humans ; Kelch-Like ECH-Associated Protein 1/genetics ; Kelch-Like ECH-Associated Protein 1/metabolism ; NF-E2-Related Factor 2/genetics ; NF-E2-Related Factor 2/metabolism ; Phospholipid Hydroperoxide Glutathione Peroxidase/genetics ; Phospholipid Hydroperoxide Glutathione Peroxidase/metabolism ; Protein Kinase Inhibitors/pharmacology ; Reverse Transcriptase Polymerase Chain Reaction ; Signal Transduction/genetics ; Sirtuins/metabolism ; Stomach Neoplasms/metabolism ; Stomach Neoplasms/pathology
Czasopismo naukowe
Tytuł :
Inhibition of SARS-CoV-2 Replication by a Small Interfering RNA Targeting the Leader Sequence.
Autorzy :
Tolksdorf B; Applied Biochemistry, Institute of Biotechnology, Technische Universität Berlin, 10623 Berlin, Germany.
Nie C; Institute of Chemistry and Biochemistry, Freie Universität Berlin, 14195 Berlin, Germany.
Niemeyer D; German Centre for Infection Research (DZIF), Charitéplatz 1, 10117 Berlin, Germany.; Institute of Virology, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.
Röhrs V; Applied Biochemistry, Institute of Biotechnology, Technische Universität Berlin, 10623 Berlin, Germany.
Berg J; Applied Biochemistry, Institute of Biotechnology, Technische Universität Berlin, 10623 Berlin, Germany.
Lauster D; Institute of Chemistry and Biochemistry, Freie Universität Berlin, 14195 Berlin, Germany.
Adler JM; Department of Veterinary Medicine, Institute of Virology, Freie Universität Berlin, 14163 Berlin, Germany.; Department of Infectious Diseases and Respiratory Medicine, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.
Haag R; Institute of Chemistry and Biochemistry, Freie Universität Berlin, 14195 Berlin, Germany.
Trimpert J; Department of Veterinary Medicine, Institute of Virology, Freie Universität Berlin, 14163 Berlin, Germany.
Kaufer B; Department of Veterinary Medicine, Institute of Virology, Freie Universität Berlin, 14163 Berlin, Germany.
Drosten C; German Centre for Infection Research (DZIF), Charitéplatz 1, 10117 Berlin, Germany.; Institute of Virology, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.
Kurreck J; Applied Biochemistry, Institute of Biotechnology, Technische Universität Berlin, 10623 Berlin, Germany.
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Źródło :
Viruses [Viruses] 2021 Oct 08; Vol. 13 (10). Date of Electronic Publication: 2021 Oct 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
RNA Interference*
Antiviral Agents/*pharmacology
COVID-19/*therapy
RNA, Small Interfering/*pharmacology
SARS-CoV-2/*growth & development
Virus Replication/*drug effects
5' Untranslated Regions/genetics ; Animals ; Cell Line, Tumor ; Chlorocebus aethiops ; Drug Evaluation, Preclinical ; HeLa Cells ; Humans ; RNA, Small Interfering/genetics ; SARS-CoV-2/genetics ; Vero Cells ; Virus Replication/genetics
SCR Organism :
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł :
Exogenous miRNAs induce post-transcriptional gene silencing in plants.
Autorzy :
Betti F; PlantLab, Institute of Life Sciences, Sant'Anna School of Advanced Studies, Pisa, Italy.
Ladera-Carmona MJ; PlantLab, Institute of Life Sciences, Sant'Anna School of Advanced Studies, Pisa, Italy.
Weits DA; PlantLab, Institute of Life Sciences, Sant'Anna School of Advanced Studies, Pisa, Italy.
Ferri G; NEST, Scuola Normale Superiore, Pisa, Italy.
Iacopino S; Department of Biology, University of Pisa, Pisa, Italy.
Novi G; PlantLab, Institute of Life Sciences, Sant'Anna School of Advanced Studies, Pisa, Italy.
Svezia B; PlantLab, Institute of Life Sciences, Sant'Anna School of Advanced Studies, Pisa, Italy.
Kunkowska AB; PlantLab, Institute of Life Sciences, Sant'Anna School of Advanced Studies, Pisa, Italy.
Santaniello A; Valagro SpA, Atessa, Italy.
Piaggesi A; Valagro SpA, Atessa, Italy.
Loreti E; Institute of Agricultural Biology and Biotechnology, National Research Council, Pisa, Italy. .
Perata P; PlantLab, Institute of Life Sciences, Sant'Anna School of Advanced Studies, Pisa, Italy. .
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Źródło :
Nature plants [Nat Plants] 2021 Oct; Vol. 7 (10), pp. 1379-1388. Date of Electronic Publication: 2021 Oct 14.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Plant*
RNA Interference*
Arabidopsis/*genetics
MicroRNAs/*genetics
RNA, Plant/*genetics
Arabidopsis/metabolism
Czasopismo naukowe
Tytuł :
Development of an RNAi-based microalgal larvicide for the control of Aedes aegypti.
Autorzy :
Fei X; Department of Biochemistry and Molecular Biology, Hainan Medical College, Haikou, 571101, China.
Zhang Y; Department of Biochemistry and Molecular Biology, Hainan Medical College, Haikou, 571101, China.
Ding L; Department of Biochemistry and Molecular Biology, Hainan Medical College, Haikou, 571101, China.
Xiao S; Department of Biochemistry and Molecular Biology, Hainan Medical College, Haikou, 571101, China.
Xie X; Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Science, Haikou, 571101, China.; Hainan Provincial Key Laboratory for Functional Components Research and Utilization of Marine Bio-Resources, Haikou, 571101, China.
Li Y; Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Science, Haikou, 571101, China.; Hainan Provincial Key Laboratory for Functional Components Research and Utilization of Marine Bio-Resources, Haikou, 571101, China.
Deng X; Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Science, Haikou, 571101, China. .; Hainan Provincial Key Laboratory for Functional Components Research and Utilization of Marine Bio-Resources, Haikou, 571101, China. .
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Źródło :
Parasites & vectors [Parasit Vectors] 2021 Aug 06; Vol. 14 (1), pp. 387. Date of Electronic Publication: 2021 Aug 06.
Typ publikacji :
Journal Article
MeSH Terms :
RNA Interference*
Aedes/*drug effects
Larva/*drug effects
Microalgae/*genetics
Mosquito Control/*methods
Animal Feed ; Animals ; Chlamydomonas/genetics ; Female ; Insecticide Resistance ; Larva/physiology ; Microalgae/drug effects ; Organisms, Genetically Modified ; Transaminases/genetics
Czasopismo naukowe
Tytuł :
Does RNAi-Based Technology Fit within EU Sustainability Goals?
Autorzy :
Taning CNT; Laboratory of Agrozoology, Department of Plants and Crops, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium. Electronic address: .
Mezzetti B; Department of Agricultural, Food, and Environmental Sciences, Università Politecnica delle Marche, Ancona, Italy.
Kleter G; Wageningen Food Safety Research, Wageningen University and Research, Wageningen, The Netherlands.
Smagghe G; Laboratory of Agrozoology, Department of Plants and Crops, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium.
Baraldi E; Department of Agricultural and Food Sciences (DISTAL), University of Bologna, viale Fanin 44, Bologna, Italy. Electronic address: .
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Źródło :
Trends in biotechnology [Trends Biotechnol] 2021 Jul; Vol. 39 (7), pp. 644-647. Date of Electronic Publication: 2020 Dec 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Agriculture*
Pest Control*/trends
RNA Interference*
European Union ; Goals ; Pesticides ; Sustainable Growth ; Technology/trends
Czasopismo naukowe
Tytuł :
Inhibition of NHE-1 Increases Smoke-Induced Proliferative Activity of Barrett's Esophageal Cell Line.
Autorzy :
Becskeházi E; Department of Pharmacology and Pharmacotherapy, University of Szeged, H-6721 Szeged, Hungary.
Korsós MM; Department of Pharmacology and Pharmacotherapy, University of Szeged, H-6721 Szeged, Hungary.
Gál E; Department of Pharmacology and Pharmacotherapy, University of Szeged, H-6721 Szeged, Hungary.
Tiszlavicz L; Department of Pathology, University of Szeged, H-6725 Szeged, Hungary.
Hoyk Z; Biological Research Centre, Institute of Biophysics, H-6726 Szeged, Hungary.
Deli MA; Biological Research Centre, Institute of Biophysics, H-6726 Szeged, Hungary.
Köhler ZM; Department of Biochemistry, University of Szeged, H-6720 Szeged, Hungary.
Keller-Pintér A; Department of Biochemistry, University of Szeged, H-6720 Szeged, Hungary.
Horváth A; Department of Pharmacognosy, University of Szeged, H-6720 Szeged, Hungary.
Csekő K; Department of Pharmacology and Pharmacotherapy, Medical School & Szentágothai Research Centre, University of Pécs, H-7624 Pécs, Hungary.; PharmInVivo Ltd., H-7629 Pécs, Hungary.
Helyes Z; Department of Pharmacology and Pharmacotherapy, Medical School & Szentágothai Research Centre, University of Pécs, H-7624 Pécs, Hungary.; PharmInVivo Ltd., H-7629 Pécs, Hungary.
Hegyi P; First Department of Medicine, University of Szeged, H-6720 Szeged, Hungary.; Medical School & Szentágothai Research Centre, Institute for Translational Medicine, University of Pécs, H-7624 Pécs, Hungary.; Division of Gastroenterology, First Department of Medicine, Medical School, University of Pécs, H-7624 Pécs, Hungary.
Venglovecz V; Department of Pharmacology and Pharmacotherapy, University of Szeged, H-6721 Szeged, Hungary.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Sep 30; Vol. 22 (19). Date of Electronic Publication: 2021 Sep 30.
Typ publikacji :
Journal Article
MeSH Terms :
RNA Interference*
Smoke*
Barrett Esophagus/*genetics
Cell Proliferation/*genetics
Esophagus/*metabolism
Sodium-Hydrogen Exchanger 1/*genetics
Animals ; Barrett Esophagus/metabolism ; Barrett Esophagus/pathology ; Cell Line ; Cell Survival ; Epithelial Cells/metabolism ; Esophagus/pathology ; Gene Expression ; Guinea Pigs ; Humans ; Hydrogen-Ion Concentration ; Male ; Middle Aged ; Smoking ; Sodium-Hydrogen Exchanger 1/metabolism ; Tobacco/chemistry
Czasopismo naukowe
Tytuł :
Novel Functions of the Fatty Acid and Retinol Binding Protein (FAR) Gene Family Revealed by Fungus-Mediated RNAi in the Parasitic Nematode, Aphelenchoides besseyi .
Autorzy :
Ding S; Laboratory of Plant Nematology and Research Center of Nematodes of Plant Quarantine, Department of Plant Pathology, College of Plant Protection, South China Agricultural University, Guangzhou 510642, China.
Xu C; Laboratory of Plant Nematology and Research Center of Nematodes of Plant Quarantine, Department of Plant Pathology, College of Plant Protection, South China Agricultural University, Guangzhou 510642, China.
Chen C; Laboratory of Plant Nematology and Research Center of Nematodes of Plant Quarantine, Department of Plant Pathology, College of Plant Protection, South China Agricultural University, Guangzhou 510642, China.
Li J; Laboratory of Plant Nematology and Research Center of Nematodes of Plant Quarantine, Department of Plant Pathology, College of Plant Protection, South China Agricultural University, Guangzhou 510642, China.
Wang J; Laboratory of Plant Nematology and Research Center of Nematodes of Plant Quarantine, Department of Plant Pathology, College of Plant Protection, South China Agricultural University, Guangzhou 510642, China.
Xie H; Laboratory of Plant Nematology and Research Center of Nematodes of Plant Quarantine, Department of Plant Pathology, College of Plant Protection, South China Agricultural University, Guangzhou 510642, China.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Sep 17; Vol. 22 (18). Date of Electronic Publication: 2021 Sep 17.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Profiling*
RNA Interference*
Botrytis/*genetics
Fatty Acid-Binding Proteins/*physiology
Nematoda/*metabolism
Nematoda/*pathogenicity
Retinol-Binding Proteins/*physiology
Animals ; Animals, Genetically Modified ; Arabidopsis/parasitology ; Fatty Acid-Binding Proteins/genetics ; Fatty Acids/chemistry ; Gene Silencing ; Helminth Proteins/genetics ; Phenotype ; Retinol-Binding Proteins/genetics ; Transcriptome
SCR Organism :
Botrytis cinerea
Czasopismo naukowe
Tytuł :
Neuroblastoma Cells Depend on CSB for Faithful Execution of Cytokinesis and Survival.
Autorzy :
Paccosi E; Unit of Molecular Genetics of Aging, Department of Ecology and Biology, University of Tuscia, 01100 Viterbo, Italy.
Costantino M; Unit of Molecular Genetics of Aging, Department of Ecology and Biology, University of Tuscia, 01100 Viterbo, Italy.
Balzerano A; Unit of Molecular Genetics of Aging, Department of Ecology and Biology, University of Tuscia, 01100 Viterbo, Italy.
Filippi S; Unit of Molecular Genetics of Aging, Department of Ecology and Biology, University of Tuscia, 01100 Viterbo, Italy.
Brancorsini S; Unit of Molecular Pathology, Department of Experimental Medicine, Section of Terni, University of Perugia, 06100 Perugia, Italy.
Proietti-De-Santis L; Unit of Molecular Genetics of Aging, Department of Ecology and Biology, University of Tuscia, 01100 Viterbo, Italy.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Sep 17; Vol. 22 (18). Date of Electronic Publication: 2021 Sep 17.
Typ publikacji :
Journal Article
MeSH Terms :
RNA Interference*
Cytokinesis/*physiology
DNA Helicases/*physiology
DNA Repair Enzymes/*physiology
Neuroblastoma/*metabolism
Poly-ADP-Ribose Binding Proteins/*physiology
Apoptosis ; Caspase 3/metabolism ; Caspase 9/metabolism ; Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Cell Survival ; Centrosome ; DNA Helicases/genetics ; DNA Helicases/metabolism ; DNA Repair ; DNA Repair Enzymes/genetics ; Humans ; Poly-ADP-Ribose Binding Proteins/genetics ; Spindle Apparatus
Czasopismo naukowe
Tytuł :
Potential of application of the RNA interference phenomenon in the treatment of new coronavirus infection COVID-19.
Autorzy :
Pashkov EA; FSAEI HE I.M. Sechenov First Moscow State Medical University (Sechenov University) of the Ministry of the Health of Russia; FSBRI «I.I. Mechnikov Research Institute of Vaccines and Sera».
Korchevaya ER; FSBRI «I.I. Mechnikov Research Institute of Vaccines and Sera».
Faizuloev EB; FSBRI «I.I. Mechnikov Research Institute of Vaccines and Sera».
Svitich OA; FSAEI HE I.M. Sechenov First Moscow State Medical University (Sechenov University) of the Ministry of the Health of Russia; FSBRI «I.I. Mechnikov Research Institute of Vaccines and Sera».
Pashkov EP; FSAEI HE I.M. Sechenov First Moscow State Medical University (Sechenov University) of the Ministry of the Health of Russia.
Nechaev DN; FSAEI HE I.M. Sechenov First Moscow State Medical University (Sechenov University) of the Ministry of the Health of Russia.
Zverev VV; FSAEI HE I.M. Sechenov First Moscow State Medical University (Sechenov University) of the Ministry of the Health of Russia; FSBRI «I.I. Mechnikov Research Institute of Vaccines and Sera».
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Źródło :
Voprosy virusologii [Vopr Virusol] 2021 Sep 16; Vol. 66 (4), pp. 241-251. Date of Electronic Publication: 2021 Sep 16.
Typ publikacji :
Journal Article; Review
MeSH Terms :
RNA Interference*
SARS-CoV-2*/genetics
SARS-CoV-2*/metabolism
Antiviral Agents/*therapeutic use
COVID-19/*drug therapy
RNA, Small Interfering/*therapeutic use
Animals ; COVID-19/genetics ; COVID-19/metabolism ; Disease Models, Animal
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
High-throughput kinome-RNAi screen identifies protein kinase R activator (PACT) as a novel genetic modifier of CUG foci integrity in myotonic dystrophy type 1 (DM1).
Autorzy :
Neault N; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.; Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada.
O'Reilly S; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.; Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada.
Baig AT; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.; Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada.
Plaza-Diaz J; Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada.
Azimi M; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.; Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada.
Farooq F; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.; Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada.
Baird SD; Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada.
MacKenzie A; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.; Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada.
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Źródło :
PloS one [PLoS One] 2021 Sep 14; Vol. 16 (9), pp. e0256276. Date of Electronic Publication: 2021 Sep 14 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
RNA Interference*
Trinucleotide Repeat Expansion*
Cell Nucleus/*metabolism
High-Throughput Screening Assays/*methods
Myotonic Dystrophy/*pathology
RNA-Binding Proteins/*antagonists & inhibitors
Case-Control Studies ; Cell Nucleus/genetics ; Fibroblasts/metabolism ; Fibroblasts/pathology ; Humans ; Myotonic Dystrophy/genetics ; Myotonic Dystrophy/metabolism ; RNA Splicing ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; RNA-Binding Proteins/genetics ; RNA-Binding Proteins/metabolism ; Sarcoplasmic Reticulum Calcium-Transporting ATPases/genetics ; Sarcoplasmic Reticulum Calcium-Transporting ATPases/metabolism
Czasopismo naukowe
Tytuł :
Efficient RNA Virus Targeting via CRISPR/CasRx in Fish.
Autorzy :
Wang Q; Joint Laboratory of Guangdong Province and Hong Kong Region on Marine Bioresource Conservation and Exploitation, College of Marine Sciences, South China Agricultural Universitygrid.20561.30, Guangzhou, China.; Guangdong Laboratory for Lingnan Modern Agriculture, Guangzhou, China.
Liu Y; State Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory for Aquatic Economic Animals and Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), School of Life Sciences, Sun Yat-Sen University, Guangzhou, China.
Han C; State Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory for Aquatic Economic Animals and Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), School of Life Sciences, Sun Yat-Sen University, Guangzhou, China.
Yang M; Joint Laboratory of Guangdong Province and Hong Kong Region on Marine Bioresource Conservation and Exploitation, College of Marine Sciences, South China Agricultural Universitygrid.20561.30, Guangzhou, China.; Guangdong Laboratory for Lingnan Modern Agriculture, Guangzhou, China.
Huang F; Joint Laboratory of Guangdong Province and Hong Kong Region on Marine Bioresource Conservation and Exploitation, College of Marine Sciences, South China Agricultural Universitygrid.20561.30, Guangzhou, China.
Duan X; Joint Laboratory of Guangdong Province and Hong Kong Region on Marine Bioresource Conservation and Exploitation, College of Marine Sciences, South China Agricultural Universitygrid.20561.30, Guangzhou, China.
Wang S; Joint Laboratory of Guangdong Province and Hong Kong Region on Marine Bioresource Conservation and Exploitation, College of Marine Sciences, South China Agricultural Universitygrid.20561.30, Guangzhou, China.; Guangdong Laboratory for Lingnan Modern Agriculture, Guangzhou, China.
Yu Y; Joint Laboratory of Guangdong Province and Hong Kong Region on Marine Bioresource Conservation and Exploitation, College of Marine Sciences, South China Agricultural Universitygrid.20561.30, Guangzhou, China.; Guangdong Laboratory for Lingnan Modern Agriculture, Guangzhou, China.
Liu J; Joint Laboratory of Guangdong Province and Hong Kong Region on Marine Bioresource Conservation and Exploitation, College of Marine Sciences, South China Agricultural Universitygrid.20561.30, Guangzhou, China.
Yang H; Joint Laboratory of Guangdong Province and Hong Kong Region on Marine Bioresource Conservation and Exploitation, College of Marine Sciences, South China Agricultural Universitygrid.20561.30, Guangzhou, China.; Guangdong Laboratory for Lingnan Modern Agriculture, Guangzhou, China.
Lu D; State Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory for Aquatic Economic Animals and Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), School of Life Sciences, Sun Yat-Sen University, Guangzhou, China.
Zhao H; Joint Laboratory of Guangdong Province and Hong Kong Region on Marine Bioresource Conservation and Exploitation, College of Marine Sciences, South China Agricultural Universitygrid.20561.30, Guangzhou, China.; Guangdong Laboratory for Lingnan Modern Agriculture, Guangzhou, China.
Zhang Y; State Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory for Aquatic Economic Animals and Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), School of Life Sciences, Sun Yat-Sen University, Guangzhou, China.; Guangdong Laboratory for Lingnan Modern Agriculture, Guangzhou, China.
Qin Q; Joint Laboratory of Guangdong Province and Hong Kong Region on Marine Bioresource Conservation and Exploitation, College of Marine Sciences, South China Agricultural Universitygrid.20561.30, Guangzhou, China.; Guangdong Laboratory for Lingnan Modern Agriculture, Guangzhou, China.; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao, China.; Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai, China.
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Źródło :
Journal of virology [J Virol] 2021 Sep 09; Vol. 95 (19), pp. e0046121. Date of Electronic Publication: 2021 Sep 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
CRISPR-Cas Systems*
RNA Interference*
CRISPR-Associated Proteins/*metabolism
Fish Diseases/*virology
Nodaviridae/*genetics
Perciformes/*virology
RNA Virus Infections/*veterinary
Animals ; Nodaviridae/physiology ; RNA Virus Infections/virology ; RNA, Viral/genetics
Czasopismo naukowe
Tytuł :
Beyond identity: Understanding the contribution of the 5' nucleotide of the antisense strand to RNAi activity.
Autorzy :
Yang P; Bayer Crop Science, St. Louis, Missouri, United States of America.
Havecker E; Bayer Crop Science, Chesterfield, Missouri, United States of America.
Bauer M; Bayer Crop Science, Chesterfield, Missouri, United States of America.
Diehl C; Bayer Crop Science, St. Louis, Missouri, United States of America.
Hendrix B; Bayer Crop Science, Woodland, California, United States of America.
Hoffer P; Bayer Crop Science, Woodland, California, United States of America.
Boyle T; Bayer Crop Science, Chesterfield, Missouri, United States of America.
Bradley J; Bayer Crop Science, Chesterfield, Missouri, United States of America.
Caruano-Yzermans A; Bayer Crop Science, Chesterfield, Missouri, United States of America.
Deikman J; Bayer Crop Science, Woodland, California, United States of America.
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Źródło :
PloS one [PLoS One] 2021 Sep 07; Vol. 16 (9), pp. e0256863. Date of Electronic Publication: 2021 Sep 07 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
RNA Interference*
Argonaute Proteins/*genetics
RNA, Small Interfering/*genetics
Tobacco/*genetics
Argonaute Proteins/antagonists & inhibitors ; Gene Expression Regulation/genetics ; Gene Silencing ; Green Fluorescent Proteins/antagonists & inhibitors ; Green Fluorescent Proteins/genetics ; Humans ; Lyases/antagonists & inhibitors ; Lyases/genetics ; Protein Binding/genetics ; Tobacco/growth & development
Czasopismo naukowe
Tytuł :
Human-Specific Regulation of Neurotrophic Factors MANF and CDNF by microRNAs.
Autorzy :
Konovalova J; Institute of Biotechnology, HiLIFE, University of Helsinki, Viikinkaari 5D, 00790 Helsinki, Finland.
Gerasymchuk D; Institute of Biotechnology, HiLIFE, University of Helsinki, Viikinkaari 5D, 00790 Helsinki, Finland.; Institute of Molecular Biology and Genetics, NASU, 03143 Kyiv, Ukraine.
Arroyo SN; Institute of Biotechnology, HiLIFE, University of Helsinki, Viikinkaari 5D, 00790 Helsinki, Finland.
Kluske S; Institute of Biotechnology, HiLIFE, University of Helsinki, Viikinkaari 5D, 00790 Helsinki, Finland.
Mastroianni F; Institute of Biotechnology, HiLIFE, University of Helsinki, Viikinkaari 5D, 00790 Helsinki, Finland.
Pereyra AV; Institute of Biotechnology, HiLIFE, University of Helsinki, Viikinkaari 5D, 00790 Helsinki, Finland.
Domanskyi A; Institute of Biotechnology, HiLIFE, University of Helsinki, Viikinkaari 5D, 00790 Helsinki, Finland.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Sep 07; Vol. 22 (18). Date of Electronic Publication: 2021 Sep 07.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation*
RNA Interference*
MicroRNAs/*genetics
Nerve Growth Factors/*genetics
3' Untranslated Regions ; Cell Line ; Endoplasmic Reticulum Stress ; Humans ; RNA, Messenger/genetics
Czasopismo naukowe
Tytuł :
Gene interfered-ferroptosis therapy for cancers.
Autorzy :
Gao J; State Key Laboratory of Bioelectronics, Southeast University, Nanjing, China.
Luo T; State Key Laboratory of Bioelectronics, Southeast University, Nanjing, China.
Wang J; State Key Laboratory of Bioelectronics, Southeast University, Nanjing, China. .
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Źródło :
Nature communications [Nat Commun] 2021 Sep 07; Vol. 12 (1), pp. 5311. Date of Electronic Publication: 2021 Sep 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
RNA Interference*
Cation Transport Proteins/*antagonists & inhibitors
Ferroptosis/*genetics
Iron/*metabolism
Lipocalin-2/*antagonists & inhibitors
Neoplasms/*therapy
Reactive Oxygen Species/*agonists
Animals ; CRISPR-Associated Proteins/genetics ; CRISPR-Associated Proteins/metabolism ; Cation Transport Proteins/genetics ; Cation Transport Proteins/metabolism ; Cell Line, Tumor ; Dependovirus/genetics ; Dependovirus/metabolism ; Gene Expression Regulation, Neoplastic ; Humans ; Lipocalin-2/genetics ; Lipocalin-2/metabolism ; Liver/metabolism ; Liver/pathology ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; MicroRNAs/genetics ; MicroRNAs/metabolism ; NF-kappa B/genetics ; NF-kappa B/metabolism ; Nanoparticles/administration & dosage ; Nanoparticles/chemistry ; Neoplasms/genetics ; Neoplasms/mortality ; Neoplasms/pathology ; Promoter Regions, Genetic ; Reactive Oxygen Species/metabolism ; Signal Transduction ; Spleen/metabolism ; Spleen/pathology ; Survival Analysis ; Tumor Burden ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Inhibiting PHD2 in human periodontal ligament cells via lentiviral vector-mediated RNA interference facilitates cell osteogenic differentiation and periodontal repair.
Autorzy :
Cui D; Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, Jiangsu, China.
Chen C; Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, Jiangsu, China.
Luo B; Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, Jiangsu, China.
Yan F; Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, Jiangsu, China.
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Źródło :
Journal of leukocyte biology [J Leukoc Biol] 2021 Sep; Vol. 110 (3), pp. 449-459. Date of Electronic Publication: 2021 May 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Differentiation*/drug effects
Cell Differentiation*/genetics
Osteogenesis*/drug effects
Osteogenesis*/genetics
RNA Interference*
Wound Healing*/drug effects
Wound Healing*/genetics
Genetic Vectors/*metabolism
Hypoxia-Inducible Factor-Proline Dioxygenases/*antagonists & inhibitors
Lentivirus/*metabolism
Periodontal Ligament/*pathology
Alkaline Phosphatase/metabolism ; Gene Expression Regulation/drug effects ; Humans ; Hydrogen Peroxide/toxicity ; Hypoxia-Inducible Factor-Proline Dioxygenases/metabolism ; Oxidative Stress/drug effects ; Oxidative Stress/genetics ; Regeneration/drug effects
Czasopismo naukowe
Tytuł :
Interference Efficiency and Effects of Bacterium-mediated RNAi in the Fall Armyworm (Lepidoptera: Noctuidae).
Autorzy :
Wan XS; Yunnan Academy of Biodiversity, Southwest Forestry University, Kunming 650224, China.
Shi MR; Yunnan Academy of Biodiversity, Southwest Forestry University, Kunming 650224, China.
Xu J; Yunnan Academy of Biodiversity, Southwest Forestry University, Kunming 650224, China.; Key Laboratory for Forest Resources Conservation and Utilization in the Southwest Mountains of China, Ministry of Education, Southwest Forestry University, Kunming 650224, China.
Liu JH; Yunnan Academy of Biodiversity, Southwest Forestry University, Kunming 650224, China.
Ye H; School of Ecology and Environment, Yunnan University, Kunming 650091, China.
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Źródło :
Journal of insect science (Online) [J Insect Sci] 2021 Sep 01; Vol. 21 (5).
Typ publikacji :
Journal Article
MeSH Terms :
RNA Interference*
Spodoptera*/drug effects
Spodoptera*/genetics
Spodoptera*/physiology
RNA, Double-Stranded/*pharmacology
Animals ; Bacteria/genetics ; Chitinases/drug effects ; Chitinases/genetics ; Fertility/drug effects ; Genes, Insect/drug effects ; Immunoglobulins/drug effects ; Immunoglobulins/genetics ; Insect Proteins/drug effects ; Insect Proteins/genetics ; Larva/drug effects ; Larva/genetics ; Larva/physiology ; Pest Control, Biological ; Pupa/drug effects ; Pupa/genetics ; Pupa/physiology ; Reproduction/drug effects
Czasopismo naukowe
Tytuł :
Immunonano-Lipocarrier-Mediated Liver Sinusoidal Endothelial Cell-Specific RUNX1 Inhibition Impedes Immune Cell Infiltration and Hepatic Inflammation in Murine Model of NASH.
Autorzy :
Tripathi DM; Department of Molecular and Cellular Medicine, Institute of Liver and Biliary Sciences, New Delhi 110070, India.
Rohilla S; School of Biotechnology, Gautam Buddha University, Greater Noida 201312, India.
Kaur I; Department of Molecular and Cellular Medicine, Institute of Liver and Biliary Sciences, New Delhi 110070, India.
Siddiqui H; Department of Molecular and Cellular Medicine, Institute of Liver and Biliary Sciences, New Delhi 110070, India.
Rawal P; School of Biotechnology, Gautam Buddha University, Greater Noida 201312, India.
Juneja P; Department of Molecular and Cellular Medicine, Institute of Liver and Biliary Sciences, New Delhi 110070, India.
Kumar V; Stem Cell Biology Laboratory, National Institute of Immunology, New Delhi 110067, India.
Kumari A; Department of Molecular and Cellular Medicine, Institute of Liver and Biliary Sciences, New Delhi 110070, India.
Naidu VGM; Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research, Guwahati 781122, India.
Ramakrishna S; Department of Mechanical Engineering, National University of Singapore, Singapore 117575, Singapore.
Banerjee S; Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research, Guwahati 781122, India.
Puria R; School of Biotechnology, Gautam Buddha University, Greater Noida 201312, India.
Sarin SK; Department of Molecular and Cellular Medicine, Institute of Liver and Biliary Sciences, New Delhi 110070, India.; Department of Hepatology, Institute of Liver and Biliary Sciences, New Delhi 110070, India.
Kaur S; Department of Molecular and Cellular Medicine, Institute of Liver and Biliary Sciences, New Delhi 110070, India.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 06; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 06.
Typ publikacji :
Journal Article
MeSH Terms :
RNA Interference*
Core Binding Factor Alpha 2 Subunit/*genetics
Inflammation/*genetics
Non-alcoholic Fatty Liver Disease/*genetics
RNA, Small Interfering/*genetics
Animals ; Disease Models, Animal ; Endothelial Cells/metabolism ; Inflammation/therapy ; Liver/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Non-alcoholic Fatty Liver Disease/therapy ; RNA, Small Interfering/therapeutic use ; RNAi Therapeutics
Czasopismo naukowe
Tytuł :
Control of postharvest fungal diseases in fruits using external application of RNAi.
Autorzy :
de Oliveira Filho JG; School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, São Paulo, Brazil.
Silva GDC; Department of Genetic and Evolution, Federal University of São Carlos, São Carlos, São Paulo, Brazil.
Cipriano L; Center for Biological Sciences and Health, Federal University of São Carlos, São Carlos, São Paulo, Brazil.
Gomes M; Department of Genetic and Evolution, Federal University of São Carlos, São Carlos, São Paulo, Brazil.
Egea MB; Goiano Federal Institute of Education, Science, and Technology, Campus Rio Verde, Rio Verde, Goiás, Brazil.
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Źródło :
Journal of food science [J Food Sci] 2021 Aug; Vol. 86 (8), pp. 3341-3348. Date of Electronic Publication: 2021 Jul 16.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Agriculture*/methods
Fruit*/microbiology
Fungi*/drug effects
Fungi*/genetics
Plant Diseases*/prevention & control
RNA Interference*
RNA/pharmacology
Czasopismo naukowe

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