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Wyszukujesz frazę ""RNA-Binding Proteins"" wg kryterium: Temat


Tytuł :
Validation and classification of RNA binding proteins identified by mRNA interactome capture.
Autorzy :
Vaishali; Developmental Biology Unit, EMBL Heidelberg, 69117 Heidelberg, Germany.; Faculty of Biosciences, Heidelberg University, Heidelberg 69120, Germany.
Dimitrova-Paternoga L; Developmental Biology Unit, EMBL Heidelberg, 69117 Heidelberg, Germany.; Structural and Computational Biology Unit, EMBL Heidelberg, 69117 Heidelberg, Germany.
Haubrich K; Structural and Computational Biology Unit, EMBL Heidelberg, 69117 Heidelberg, Germany.
Sun M; Genome Biology Unit, EMBL Heidelberg, 69117 Heidelberg, Germany.
Ephrussi A; Developmental Biology Unit, EMBL Heidelberg, 69117 Heidelberg, Germany.
Hennig J; Structural and Computational Biology Unit, EMBL Heidelberg, 69117 Heidelberg, Germany.; Biochemistry IV, Biophysical Chemistry, University of Bayreuth, 95447 Bayreuth, Germany.
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Źródło :
RNA (New York, N.Y.) [RNA] 2021 Oct; Vol. 27 (10), pp. 1173-1185. Date of Electronic Publication: 2021 Jul 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Validation Study
MeSH Terms :
Drosophila Proteins/*metabolism
Dystrophin-Associated Proteins/*metabolism
Microtubule-Associated Proteins/*metabolism
RNA/*metabolism
RNA-Binding Proteins/*metabolism
Thioredoxins/*metabolism
Transcription Factors/*metabolism
Tripartite Motif Proteins/*metabolism
Ubiquitin-Protein Ligases/*metabolism
Animals ; Binding Sites ; Cloning, Molecular ; Drosophila Proteins/chemistry ; Drosophila Proteins/genetics ; Drosophila melanogaster/genetics ; Drosophila melanogaster/metabolism ; Dystrophin-Associated Proteins/chemistry ; Dystrophin-Associated Proteins/genetics ; Electrophoretic Mobility Shift Assay ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Female ; Gene Expression ; Genetic Vectors/chemistry ; Genetic Vectors/metabolism ; Humans ; Microtubule-Associated Proteins/chemistry ; Microtubule-Associated Proteins/genetics ; Microtubules/metabolism ; Microtubules/ultrastructure ; Models, Molecular ; Ovary/cytology ; Ovary/metabolism ; Poly U/chemistry ; Poly U/genetics ; Poly U/metabolism ; Protein Binding ; RNA/chemistry ; RNA/genetics ; RNA-Binding Proteins/chemistry ; RNA-Binding Proteins/genetics ; Recombinant Proteins/chemistry ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Thioredoxins/chemistry ; Thioredoxins/genetics ; Transcription Factors/chemistry ; Transcription Factors/genetics ; Tripartite Motif Proteins/chemistry ; Tripartite Motif Proteins/genetics ; Ubiquitin-Protein Ligases/chemistry ; Ubiquitin-Protein Ligases/genetics
Czasopismo naukowe
Tytuł :
A budding yeast model for human disease mutations in the EXOSC2 cap subunit of the RNA exosome complex.
Autorzy :
Sterrett MC; Biochemistry, Cell and Developmental Biology Graduate Program, Emory University, Atlanta, Georgia 30322, USA.; Department of Biology, Emory University, Atlanta, Georgia 30322, USA.
Enyenihi L; Department of Biology, Emory University, Atlanta, Georgia 30322, USA.
Leung SW; Department of Biology, Emory University, Atlanta, Georgia 30322, USA.
Hess L; Department of Biology, Emory University, Atlanta, Georgia 30322, USA.
Strassler SE; Biochemistry, Cell and Developmental Biology Graduate Program, Emory University, Atlanta, Georgia 30322, USA.; Department of Biochemistry, Emory University, Atlanta, Georgia 30322, USA.
Farchi D; Department of Biology, Emory University, Atlanta, Georgia 30322, USA.
Lee RS; Department of Biology, Emory University, Atlanta, Georgia 30322, USA.
Withers ES; Department of Biology, Emory University, Atlanta, Georgia 30322, USA.
Kremsky I; Loma Linda University School of Medicine, Loma Linda, California 92350, USA.
Baker RE; Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA.
Basrai MA; Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
van Hoof A; Department of Microbiology and Molecular Genetics, University of Texas Health Science Center at Houston, Houston, Texas 77030, USA.
Fasken MB; Department of Biology, Emory University, Atlanta, Georgia 30322, USA.
Corbett AH; Department of Biology, Emory University, Atlanta, Georgia 30322, USA.
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Źródło :
RNA (New York, N.Y.) [RNA] 2021 Sep; Vol. 27 (9), pp. 1046-1067. Date of Electronic Publication: 2021 Jun 23.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Mutation, Missense*
Exoribonucleases/*genetics
Exosome Multienzyme Ribonuclease Complex/*genetics
RNA, Fungal/*genetics
RNA-Binding Proteins/*genetics
Saccharomyces cerevisiae/*genetics
Saccharomyces cerevisiae Proteins/*genetics
Amino Acid Sequence ; Amino Acid Substitution ; Aspartic Acid/chemistry ; Aspartic Acid/metabolism ; Dwarfism/enzymology ; Dwarfism/genetics ; Dwarfism/pathology ; Exoribonucleases/chemistry ; Exoribonucleases/metabolism ; Exosome Multienzyme Ribonuclease Complex/chemistry ; Exosome Multienzyme Ribonuclease Complex/metabolism ; Facies ; Gene Expression ; Glycine/chemistry ; Glycine/metabolism ; Hearing Loss/enzymology ; Hearing Loss/genetics ; Hearing Loss/pathology ; Humans ; Models, Biological ; Models, Molecular ; Protein Conformation ; RNA, Fungal/chemistry ; RNA, Fungal/metabolism ; RNA-Binding Proteins/chemistry ; RNA-Binding Proteins/metabolism ; Retinitis Pigmentosa/enzymology ; Retinitis Pigmentosa/genetics ; Retinitis Pigmentosa/pathology ; Saccharomyces cerevisiae/enzymology ; Saccharomyces cerevisiae Proteins/chemistry ; Saccharomyces cerevisiae Proteins/metabolism ; Sequence Homology, Amino Acid ; Syndrome
Czasopismo naukowe
Tytuł :
Identification of gene targets of mutant C/EBPα reveals a critical role for MSI2 in CEBPA-mutated AML.
Autorzy :
Heyes E; University of Veterinary Medicine, Institute of Medical Biochemistry, Vienna, Austria.
Schmidt L; University of Veterinary Medicine, Institute of Medical Biochemistry, Vienna, Austria.
Manhart G; University of Veterinary Medicine, Institute of Medical Biochemistry, Vienna, Austria.
Eder T; University of Veterinary Medicine, Institute of Medical Biochemistry, Vienna, Austria.
Proietti L; University of Veterinary Medicine, Institute of Medical Biochemistry, Vienna, Austria.
Grebien F; University of Veterinary Medicine, Institute of Medical Biochemistry, Vienna, Austria. .
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Źródło :
Leukemia [Leukemia] 2021 Sep; Vol. 35 (9), pp. 2526-2538. Date of Electronic Publication: 2021 Feb 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Mutation*
Biomarkers, Tumor/*genetics
CCAAT-Enhancer-Binding Proteins/*genetics
Leukemia, Myeloid, Acute/*pathology
RNA, Small Interfering/*genetics
RNA-Binding Proteins/*metabolism
Animals ; CCAAT-Enhancer-Binding Proteins/antagonists & inhibitors ; CCAAT-Enhancer-Binding Proteins/metabolism ; CRISPR-Cas Systems ; Cell Differentiation ; Hematopoiesis ; Humans ; Leukemia, Myeloid, Acute/genetics ; Leukemia, Myeloid, Acute/metabolism ; Mice ; Prognosis ; RNA-Binding Proteins/antagonists & inhibitors ; RNA-Binding Proteins/genetics
Czasopismo naukowe
Tytuł :
RNA-Binding Proteins PCBP1 and PCBP2 Are Critical Determinants of Murine Erythropoiesis.
Autorzy :
Ji X; Department of Genetics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Jha A; Department of Computer and Information Science, School of Engineering and Applied Science at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Humenik J; Department of Genetics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Ghanem LR; Gastroenterology, Hepatology and Nutrition Division, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Kromer A; Department of Genetics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Duncan-Lewis C; Department of Genetics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Traxler E; Cell and Molecular Biology Graduate Group, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Weiss MJ; Department of Hematology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Barash Y; Department of Genetics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Liebhaber SA; Department of Genetics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
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Źródło :
Molecular and cellular biology [Mol Cell Biol] 2021 Aug 24; Vol. 41 (9), pp. e0066820. Date of Electronic Publication: 2021 Aug 24.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Erythropoiesis*
DNA-Binding Proteins/*metabolism
RNA-Binding Proteins/*metabolism
Aging/physiology ; Animals ; Cell Lineage ; DNA-Binding Proteins/genetics ; Embryo, Mammalian/metabolism ; Erythroid Cells/cytology ; Exons/genetics ; Genetic Loci ; Hematopoietic Stem Cells/metabolism ; Mice ; RNA Splicing/genetics ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; RNA-Binding Proteins/genetics ; Transcriptome/genetics
Czasopismo naukowe
Tytuł :
Mammalian retrovirus-like protein PEG10 packages its own mRNA and can be pseudotyped for mRNA delivery.
Autorzy :
Segel M; Howard Hughes Medical Institute, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Brain and Cognitive Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Lash B; Howard Hughes Medical Institute, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Brain and Cognitive Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Song J; Howard Hughes Medical Institute, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Brain and Cognitive Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Ladha A; Howard Hughes Medical Institute, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Brain and Cognitive Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Liu CC; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Howard Hughes Medical Institute, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Brain and Cognitive Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Jin X; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Brain and Cognitive Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Society of Fellows, Harvard University, Cambridge, MA 02138 USA.
Mekhedov SL; National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA.
Macrae RK; Howard Hughes Medical Institute, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Brain and Cognitive Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Koonin EV; National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA.
Zhang F; Howard Hughes Medical Institute, Cambridge, MA 02139, USA.; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Brain and Cognitive Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
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Źródło :
Science (New York, N.Y.) [Science] 2021 Aug 20; Vol. 373 (6557), pp. 882-889.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis Regulatory Proteins/*metabolism
DNA-Binding Proteins/*metabolism
RNA, Messenger/*genetics
RNA, Messenger/*metabolism
RNA-Binding Proteins/*metabolism
Animals ; Apoptosis Regulatory Proteins/chemistry ; Apoptosis Regulatory Proteins/genetics ; Capsid/metabolism ; Cell Line ; DNA-Binding Proteins/chemistry ; DNA-Binding Proteins/genetics ; Extracellular Vesicles/metabolism ; Gene Editing ; Genetic Vectors ; Humans ; Mice ; Neurons/metabolism ; Protein Domains ; RNA-Binding Proteins/chemistry ; RNA-Binding Proteins/genetics ; Retroelements ; Transfection ; Untranslated Regions ; Up-Regulation
Czasopismo naukowe
Tytuł :
Structures of tmRNA and SmpB as they transit through the ribosome.
Autorzy :
Guyomar C; Univ. Rennes, CNRS, Institut de Génétique et Développement de Rennes (IGDR) UMR 6290, Rennes, France.
D'Urso G; Univ. Rennes, CNRS, Institut de Génétique et Développement de Rennes (IGDR) UMR 6290, Rennes, France.
Chat S; Univ. Rennes, CNRS, Institut de Génétique et Développement de Rennes (IGDR) UMR 6290, Rennes, France.
Giudice E; Univ. Rennes, CNRS, Institut de Génétique et Développement de Rennes (IGDR) UMR 6290, Rennes, France. .
Gillet R; Univ. Rennes, CNRS, Institut de Génétique et Développement de Rennes (IGDR) UMR 6290, Rennes, France. .
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Źródło :
Nature communications [Nat Commun] 2021 Aug 13; Vol. 12 (1), pp. 4909. Date of Electronic Publication: 2021 Aug 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Escherichia coli/*genetics
Escherichia coli Proteins/*genetics
Protein Biosynthesis/*genetics
RNA, Bacterial/*genetics
RNA-Binding Proteins/*genetics
Ribosomes/*genetics
Binding Sites/genetics ; Cryoelectron Microscopy ; Escherichia coli/metabolism ; Escherichia coli Proteins/metabolism ; Models, Molecular ; Nucleic Acid Conformation ; Protein Binding ; Protein Domains ; RNA, Bacterial/chemistry ; RNA, Bacterial/metabolism ; RNA, Messenger/chemistry ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; RNA, Transfer/chemistry ; RNA, Transfer/genetics ; RNA, Transfer/metabolism ; RNA-Binding Proteins/chemistry ; RNA-Binding Proteins/metabolism ; Ribosomes/metabolism ; Ribosomes/ultrastructure
Czasopismo naukowe
Tytuł :
Puf6 primes 60S pre-ribosome nuclear export at low temperature.
Autorzy :
Gerhardy S; Institute of Medical Microbiology, University of Zurich, Zurich, Switzerland.; Institute of Biochemistry, ETH Zurich, Zurich, Switzerland.; Department of Early Discovery Biochemistry, Genentech Inc., South San Francisco, CA, USA.
Oborská-Oplová M; Institute of Medical Microbiology, University of Zurich, Zurich, Switzerland.; Institute of Biochemistry, ETH Zurich, Zurich, Switzerland.
Gillet L; Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland.
Börner R; Department of Chemistry, University of Zurich, Zurich, Switzerland.; Laserinstitut Hochschule Mittweida, University of Applied Sciences Mittweida, Mittweida, Germany.
van Nues R; Centre for Synthetic and Systems Biology (SynthSys), University of Edinburgh, Edinburgh, UK.; Institute of Cell Biology, University of Edinburgh, Edinburgh, UK.
Leitner A; Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland.
Michel E; Department of Biochemistry, University of Zurich, Zurich, Switzerland.
Petkowski JJ; Institute of Biochemistry, ETH Zurich, Zurich, Switzerland.; Department of Earth, Atmospheric, and Planetary Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.
Granneman S; Centre for Synthetic and Systems Biology (SynthSys), University of Edinburgh, Edinburgh, UK.
Sigel RKO; Department of Chemistry, University of Zurich, Zurich, Switzerland.
Aebersold R; Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland.; Faculty of Science, University of Zurich, Zurich, Switzerland.
Panse VG; Institute of Medical Microbiology, University of Zurich, Zurich, Switzerland. .; Faculty of Science, University of Zurich, Zurich, Switzerland. .
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Źródło :
Nature communications [Nat Commun] 2021 Aug 04; Vol. 12 (1), pp. 4696. Date of Electronic Publication: 2021 Aug 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Nucleus/*metabolism
RNA-Binding Proteins/*metabolism
Ribosome Subunits, Large, Eukaryotic/*metabolism
Saccharomyces cerevisiae Proteins/*metabolism
Active Transport, Cell Nucleus ; Cold Temperature ; GTP Phosphohydrolases/metabolism ; Mutation ; Protein Binding ; Protein Interaction Domains and Motifs ; Proteome/metabolism ; RNA Folding ; RNA Precursors/chemistry ; RNA Precursors/metabolism ; RNA, Ribosomal/chemistry ; RNA, Ribosomal/metabolism ; RNA-Binding Proteins/chemistry ; RNA-Binding Proteins/genetics ; Ribosome Subunits, Large, Eukaryotic/chemistry ; Ribosomes/metabolism ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism ; Saccharomyces cerevisiae/physiology ; Saccharomyces cerevisiae Proteins/chemistry ; Saccharomyces cerevisiae Proteins/genetics
Czasopismo naukowe
Tytuł :
QKI-Regulated Alternative Splicing Events in Cervical Cancer: Pivotal Mechanism and Potential Therapeutic Strategy.
Autorzy :
Luo Y; Laboratory of Integrative Medicine, The First Affiliated Hospital, Dalian Medical University, Dalian, China.; Department of General Surgery, The First Affiliated Hospital, Dalian Medical University, Dalian, China.; Institute (College) of Integrative Medicine, Dalian Medical University, Dalian, China.
Li Y; Advanced Institute for Medical Sciences, Dalian Medical University, Dalian, China.
Ge P; Laboratory of Integrative Medicine, The First Affiliated Hospital, Dalian Medical University, Dalian, China.; Department of General Surgery, The First Affiliated Hospital, Dalian Medical University, Dalian, China.; Institute (College) of Integrative Medicine, Dalian Medical University, Dalian, China.
Zhang K; Department of Gynecology and Obstetrics, Central Hospital of Zhuanghe City, Zhuanghe, China.
Liu H; Laboratory of Integrative Medicine, The First Affiliated Hospital, Dalian Medical University, Dalian, China.; Department of General Surgery, The First Affiliated Hospital, Dalian Medical University, Dalian, China.; Institute (College) of Integrative Medicine, Dalian Medical University, Dalian, China.
Jiang N; Department of Gynecology and Obstetrics, The First Affiliated Hospital, Dalian Medical University, Dalian, China.
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Źródło :
DNA and cell biology [DNA Cell Biol] 2021 Oct; Vol. 40 (10), pp. 1261-1277. Date of Electronic Publication: 2021 Sep 22.
Typ publikacji :
Journal Article
MeSH Terms :
Alternative Splicing*
Gene Expression Regulation, Neoplastic*
RNA-Binding Proteins/*genetics
Uterine Cervical Neoplasms/*genetics
Female ; HeLa Cells ; Humans ; RNA-Binding Proteins/metabolism ; Transcriptome ; Uterine Cervical Neoplasms/metabolism
Czasopismo naukowe
Tytuł :
Dact1 is expressed during chicken and mouse skeletal myogenesis and modulated in human muscle diseases.
Autorzy :
Contriciani RE; Department of Biochemistry and Tissue Biology, University of Campinas - UNICAMP, Campinas, SP, Brazil.
da Veiga FC; Department of Biochemistry and Tissue Biology, University of Campinas - UNICAMP, Campinas, SP, Brazil.
do Amaral MJ; Faculty of Pharmacy, Federal University of Rio de Janeiro - UFRJ, Rio de Janeiro, RJ, Brazil.
Castelucci BG; Department of Biochemistry and Tissue Biology, University of Campinas - UNICAMP, Campinas, SP, Brazil.
de Sousa LM; Department of Biochemistry and Tissue Biology, University of Campinas - UNICAMP, Campinas, SP, Brazil.
de Jesus MB; Department of Biochemistry and Tissue Biology, University of Campinas - UNICAMP, Campinas, SP, Brazil.
Consonni SR; Department of Biochemistry and Tissue Biology, University of Campinas - UNICAMP, Campinas, SP, Brazil.
Collares-Buzato CB; Department of Biochemistry and Tissue Biology, University of Campinas - UNICAMP, Campinas, SP, Brazil.
Mermelstein C; Biomedical Sciences Institute, Federal University of Rio de Janeiro - UFRJ, Rio de Janeiro, RJ, Brazil.
Dietrich S; Institute of Biomedical and Biomolecular Sciences, University of Portsmouth, Portsmouth, UK.
Alvares LE; Department of Biochemistry and Tissue Biology, University of Campinas - UNICAMP, Campinas, SP, Brazil. Electronic address: .
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Źródło :
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology [Comp Biochem Physiol B Biochem Mol Biol] 2021 Oct-Dec; Vol. 256, pp. 110645. Date of Electronic Publication: 2021 Jul 09.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Developmental*
Muscle Development*
Adaptor Proteins, Signal Transducing/*metabolism
Muscle, Skeletal/*metabolism
Muscular Diseases/*metabolism
Myoblasts/*metabolism
Nuclear Proteins/*metabolism
RNA-Binding Proteins/*metabolism
Adaptor Proteins, Signal Transducing/genetics ; Animals ; Cell Differentiation ; Cell Nucleus/metabolism ; Cell Proliferation ; Chickens ; Female ; Humans ; Mice ; Muscle, Skeletal/cytology ; Muscular Diseases/pathology ; Myoblasts/cytology ; Nuclear Proteins/genetics ; RNA-Binding Proteins/genetics
Czasopismo naukowe
Tytuł :
Recruitment of endoplasmic reticulum-targeted and cytosolic mRNAs into membrane-associated stress granules.
Autorzy :
Child JR; Department of Cell Biology, Duke University School of Medicine, Durham, North Carolina 27710, USA.
Chen Q; Department of Cell Biology, Duke University School of Medicine, Durham, North Carolina 27710, USA.
Reid DW; Department of Cell Biology, Duke University School of Medicine, Durham, North Carolina 27710, USA.
Jagannathan S; Department of Biochemistry and Molecular Genetics, University of Colorado, Anschutz Medical Campus, Denver, Colorado 80045, USA.; RNA Bioscience Initiative, University of Colorado, Anschutz Medical Campus, Denver, Colorado 80045, USA.
Nicchitta CV; Department of Cell Biology, Duke University School of Medicine, Durham, North Carolina 27710, USA.
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Źródło :
RNA (New York, N.Y.) [RNA] 2021 Oct; Vol. 27 (10), pp. 1241-1256. Date of Electronic Publication: 2021 Jul 08.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Unfolded Protein Response*
Cytoplasmic Granules/*genetics
Endoplasmic Reticulum/*genetics
RNA, Messenger/*genetics
RNA-Binding Proteins/*genetics
Biomarkers/metabolism ; Cytoplasmic Granules/drug effects ; Cytoplasmic Granules/metabolism ; Cytoplasmic Granules/ultrastructure ; Cytosol/drug effects ; Cytosol/metabolism ; Dactinomycin/pharmacology ; Diterpenes/pharmacology ; Dithiothreitol/pharmacology ; Endoplasmic Reticulum/drug effects ; Endoplasmic Reticulum/metabolism ; Epoxy Compounds/pharmacology ; Gene Expression ; HeLa Cells ; Heat-Shock Proteins/genetics ; Heat-Shock Proteins/metabolism ; Humans ; Membrane Glycoproteins/genetics ; Membrane Glycoproteins/metabolism ; Organelle Biogenesis ; Peptide Chain Initiation, Translational/drug effects ; Phenanthrenes/pharmacology ; RNA, Messenger/metabolism ; RNA-Binding Proteins/metabolism ; Single Molecule Imaging ; Stress, Physiological/drug effects ; Transcription, Genetic/drug effects ; beta 2-Microglobulin/genetics ; beta 2-Microglobulin/metabolism
Czasopismo naukowe
Tytuł :
Nanog-mediated stem cell properties are critical for MBNL3-associated paclitaxel resistance of ovarian cancer.
Autorzy :
Sun X; Department of Gynecology, Zibo Central Hospital, No. 54 of Gongqingtuan West Road, Zhangdian District, Zibo 255000, Shandong, China.
Diao X; Department of Reproductive Medicine, Binzhou Medical University Hospital, No. 661 of Huanghe 2 Road, Binzhou 256600, Shandong, China.
Zhu X; Department of Gynecology, Zibo Central Hospital, No. 54 of Gongqingtuan West Road, Zhangdian District, Zibo 255000, Shandong, China.
Yin X; Department of Gynecology, Zibo Central Hospital, No. 54 of Gongqingtuan West Road, Zhangdian District, Zibo 255000, Shandong, China.
Cheng G; Department of Gynecology, Zibo Central Hospital, No. 54 of Gongqingtuan West Road, Zhangdian District, Zibo 255000, Shandong, China.
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Źródło :
Journal of biochemistry [J Biochem] 2021 Sep 07; Vol. 169 (6), pp. 747-756.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Biomarkers, Tumor/*metabolism
Nanog Homeobox Protein/*metabolism
Ovarian Neoplasms/*drug therapy
Paclitaxel/*pharmacology
RNA-Binding Proteins/*metabolism
Stem Cells/*pathology
Animals ; Antineoplastic Agents, Phytogenic/pharmacology ; Apoptosis ; Biomarkers, Tumor/genetics ; Cell Proliferation ; Cystadenocarcinoma, Serous/drug therapy ; Cystadenocarcinoma, Serous/metabolism ; Cystadenocarcinoma, Serous/pathology ; Female ; Humans ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Middle Aged ; Nanog Homeobox Protein/genetics ; Ovarian Neoplasms/metabolism ; Ovarian Neoplasms/pathology ; Prognosis ; RNA-Binding Proteins/genetics ; Stem Cells/metabolism ; Survival Rate ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
MUSASHI-2 confers resistance to third-generation EGFR-tyrosine kinase inhibitor osimertinib in lung adenocarcinoma.
Autorzy :
Yiming R; Division of Cancer Cell Biology, Cancer Research Institute, Kanazawa University, Kanazawa City, Japan.
Takeuchi Y; Division of Cancer Cell Biology, Cancer Research Institute, Kanazawa University, Kanazawa City, Japan.
Nishimura T; Division of Cancer Cell Biology, Cancer Research Institute, Kanazawa University, Kanazawa City, Japan.
Li M; Division of Cancer Cell Biology, Cancer Research Institute, Kanazawa University, Kanazawa City, Japan.
Wang Y; Division of Cancer Cell Biology, Cancer Research Institute, Kanazawa University, Kanazawa City, Japan.
Meguro-Horike M; Division of Functional Genomics, Advanced Science Research Center, Kanazawa University, Kanazawa City, Japan.
Kohno T; Division of Genome Biology, National Cancer Center Research Institute, Tokyo, Japan.
Horike SI; Division of Functional Genomics, Advanced Science Research Center, Kanazawa University, Kanazawa City, Japan.
Nakata A; Division of Cancer Cell Biology, Cancer Research Institute, Kanazawa University, Kanazawa City, Japan.
Gotoh N; Division of Cancer Cell Biology, Cancer Research Institute, Kanazawa University, Kanazawa City, Japan.
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Źródło :
Cancer science [Cancer Sci] 2021 Sep; Vol. 112 (9), pp. 3810-3821. Date of Electronic Publication: 2021 Jul 13.
Typ publikacji :
Journal Article
MeSH Terms :
Up-Regulation*
Acrylamides/*pharmacology
Adenocarcinoma of Lung/*metabolism
Aniline Compounds/*pharmacology
Drug Resistance, Neoplasm/*drug effects
Gefitinib/*pharmacology
Lung Neoplasms/*metabolism
Protein Kinase Inhibitors/*pharmacology
RNA-Binding Proteins/*metabolism
A549 Cells ; Acrylamides/therapeutic use ; Adenocarcinoma of Lung/pathology ; Aniline Compounds/therapeutic use ; Carcinoma, Non-Small-Cell Lung/drug therapy ; Carcinoma, Non-Small-Cell Lung/genetics ; Carcinoma, Non-Small-Cell Lung/metabolism ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Cell Survival/genetics ; Drug Resistance, Neoplasm/genetics ; ErbB Receptors/antagonists & inhibitors ; ErbB Receptors/genetics ; Gefitinib/therapeutic use ; Gene Expression Profiling ; Gene Knockdown Techniques ; Humans ; Lung Neoplasms/pathology ; Mutation ; Nanog Homeobox Protein/metabolism ; Protein Kinase Inhibitors/therapeutic use ; RNA-Binding Proteins/genetics ; Transcriptome ; Transfection
Czasopismo naukowe
Tytuł :
ADAR RNA Modifications, the Epitranscriptome and Innate Immunity.
Autorzy :
Quin J; Central European Institute of Technology, Masaryk University Brno, Kamenice 753/5, Pavilion A35, Brno CZ-62500, Czech Republic.
Sedmík J; Central European Institute of Technology, Masaryk University Brno, Kamenice 753/5, Pavilion A35, Brno CZ-62500, Czech Republic.
Vukić D; Central European Institute of Technology, Masaryk University Brno, Kamenice 753/5, Pavilion A35, Brno CZ-62500, Czech Republic.
Khan A; Central European Institute of Technology, Masaryk University Brno, Kamenice 753/5, Pavilion A35, Brno CZ-62500, Czech Republic.
Keegan LP; Central European Institute of Technology, Masaryk University Brno, Kamenice 753/5, Pavilion A35, Brno CZ-62500, Czech Republic. Electronic address: .
O'Connell MA; Central European Institute of Technology, Masaryk University Brno, Kamenice 753/5, Pavilion A35, Brno CZ-62500, Czech Republic. Electronic address: .
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Źródło :
Trends in biochemical sciences [Trends Biochem Sci] 2021 Sep; Vol. 46 (9), pp. 758-771. Date of Electronic Publication: 2021 Mar 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Immunity, Innate*
RNA Editing*
RNA-Binding Proteins*/metabolism
Adenosine Deaminase/genetics ; Adenosine Deaminase/metabolism ; Humans ; RNA, Double-Stranded ; Transcriptome
Czasopismo naukowe
Tytuł :
Zinc finger antiviral protein (ZAP) inhibits small ruminant morbillivirus replication in vitro.
Autorzy :
Tang A; Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, 200241, PR China.
Tang J; Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, 200241, PR China.
Miao Q; Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, 200241, PR China.
Zhu J; Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, 200241, PR China.
Guo H; Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, 200241, PR China.
Liu C; Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, 200241, PR China.
Meng C; Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, 200241, PR China.
Li C; Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, 200241, PR China.
Chen Z; Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, 200241, PR China.
Liu G; Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, 200241, PR China. Electronic address: .
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Źródło :
Veterinary microbiology [Vet Microbiol] 2021 Sep; Vol. 260, pp. 109163. Date of Electronic Publication: 2021 Jun 23.
Typ publikacji :
Journal Article
MeSH Terms :
Morbillivirus/*physiology
Morbillivirus Infections/*veterinary
RNA-Binding Proteins/*metabolism
Animals ; Chlorocebus aethiops ; Endometrium/virology ; Epithelial Cells/virology ; Female ; HEK293 Cells ; Humans ; Morbillivirus Infections/virology ; RNA, Viral/genetics ; RNA-Binding Proteins/genetics ; Sheep ; Vero Cells ; Virus Replication
Czasopismo naukowe
Tytuł :
Impact of scaffolding protein TNRC6 paralogs on gene expression and splicing.
Autorzy :
Johnson ST; UT Southwestern Medical Center, Departments of Pharmacology and Biochemistry, Dallas, Texas 75205, USA.
Chu Y; UT Southwestern Medical Center, Departments of Pharmacology and Biochemistry, Dallas, Texas 75205, USA.
Liu J; UT Southwestern Medical Center, Departments of Pharmacology and Biochemistry, Dallas, Texas 75205, USA.
Corey DR; UT Southwestern Medical Center, Departments of Pharmacology and Biochemistry, Dallas, Texas 75205, USA.
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Źródło :
RNA (New York, N.Y.) [RNA] 2021 Sep; Vol. 27 (9), pp. 1004-1016. Date of Electronic Publication: 2021 Jun 09.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Alternative Splicing*
Autoantigens/*genetics
RNA-Binding Proteins/*genetics
Argonaute Proteins/deficiency ; Argonaute Proteins/genetics ; Autoantigens/metabolism ; Binding Sites ; Cell Line, Tumor ; Exons ; Gene Knockout Techniques ; HCT116 Cells ; Humans ; Immunoprecipitation ; Introns ; Protein Binding ; RNA-Binding Proteins/metabolism ; Sequence Analysis, RNA
Czasopismo naukowe
Tytuł :
RNA-binding protein SAMD4A inhibits breast tumor angiogenesis by modulating the balance of angiogenesis program.
Autorzy :
Zhou M; Department of Endocrinology, Beijing Jishuitan Hospital, The 4th Clinical Medical College of Peking University, Beijing, China.
Wang B; Institute of Microcirculation, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Li H; Institute of Microcirculation, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Han J; Institute of Microcirculation, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Li A; Institute of Microcirculation, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Lu W; Institute of Microcirculation, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
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Źródło :
Cancer science [Cancer Sci] 2021 Sep; Vol. 112 (9), pp. 3835-3845. Date of Electronic Publication: 2021 Jul 16.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Neoplastic*
Breast Neoplasms/*blood supply
Neovascularization, Pathologic/*genetics
Neovascularization, Pathologic/*metabolism
RNA-Binding Proteins/*metabolism
Repressor Proteins/*metabolism
Tumor Suppressor Proteins/*metabolism
Animals ; Disease Progression ; Female ; HEK293 Cells ; Humans ; MCF-7 Cells ; Mammary Glands, Human/cytology ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; RNA-Binding Proteins/genetics ; Repressor Proteins/genetics ; Transfection ; Tumor Burden/genetics ; Tumor Suppressor Proteins/genetics ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Expanding the binding specificity for RNA recognition by a PUF domain.
Autorzy :
Zhou W; Department of Genome Sciences, University of Washington, Seattle, Washington, USA.; Molecular and Cellular Biology Program, University of Washington, Seattle, Washington, USA.; The Rockefeller University, New York, NY, USA.
Melamed D; Department of Genome Sciences, University of Washington, Seattle, Washington, USA.; Department of Evolutionary and Environmental Biology, University of Haifa, Haifa, Israel.; Institute of Evolution, University of Haifa, Haifa, Israel.
Banyai G; The Rockefeller University, New York, NY, USA.
Meyer C; The Rockefeller University, New York, NY, USA.
Tuschl T; The Rockefeller University, New York, NY, USA.
Wickens M; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI, USA.
Cao J; The Rockefeller University, New York, NY, USA. .
Fields S; Department of Genome Sciences, University of Washington, Seattle, Washington, USA. .; Department of Medicine, University of Washington, Seattle, Washington, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 Aug 24; Vol. 12 (1), pp. 5107. Date of Electronic Publication: 2021 Aug 24.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Protein Binding*
Protein Domains*
RNA/*metabolism
RNA-Binding Proteins/*metabolism
Binding Sites ; Crystallography, X-Ray ; Models, Molecular ; Protein Conformation ; RNA/chemistry ; RNA-Binding Motifs ; RNA-Binding Proteins/chemistry ; Saccharomyces cerevisiae/metabolism
Czasopismo naukowe
Tytuł :
[7SK truncation at 128-179 nt suppresses embryonic stem cell proliferation in vitro by downregulating CDC6].
Autorzy :
Chen R; First Affiliated Hospital of Xi'an Medical University, Xi'an 710077, China.
Zhang Y; First Affiliated Hospital of Xi'an Medical University, Xi'an 710077, China.
Chen P; Institute of Basic Medical Science, Xi'an Medical University, Xi'an 710021, China.
Pang Y; Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710004, China.
Li H; Department of Physiology and Pathophysiology, Xi'an Jiaotong University School of Basic Medical Sciences, Xi'an 710061, China.
Chen Z; School of Clinical Medicine, Xi'an MedicalUniversity, Xi'an710021, China.
Zhang X; First Affiliated Hospital of Xi'an Medical University, Xi'an 710077, China.
Zhang H; First Affiliated Hospital of Xi'an Medical University, Xi'an 710077, China.
Li W; First Affiliated Hospital of Xi'an Medical University, Xi'an 710077, China.
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Źródło :
Nan fang yi ke da xue xue bao = Journal of Southern Medical University [Nan Fang Yi Ke Da Xue Xue Bao] 2021 Aug 20; Vol. 41 (8), pp. 1125-1130.
Typ publikacji :
Journal Article
MeSH Terms :
Positive Transcriptional Elongation Factor B*/metabolism
RNA-Binding Proteins*
RNA, Long Noncoding/*genetics
Cell Cycle Proteins ; Cell Proliferation ; Embryonic Stem Cells/metabolism ; HeLa Cells ; Humans ; Nuclear Proteins ; Ribonucleoproteins ; Transcription Factors
Czasopismo naukowe
Tytuł :
Pumilio2 Promotes Growth of Mature Neurons.
Autorzy :
Schieweck R; Biomedical Center (BMC), Department for Cell Biology & Anatomy, Medical Faculty, Ludwig-Maximilians-University, 82152 München, Germany.
Schöneweiss EC; Zentrum für Medizinische Biotechnologie (ZMB), University of Duisburg-Essen, 41541 Duisburg, Germany.
Harner M; Biomedical Center (BMC), Department for Cell Biology & Anatomy, Medical Faculty, Ludwig-Maximilians-University, 82152 München, Germany.
Rieger D; Biomedical Center (BMC), Department for Cell Biology & Anatomy, Medical Faculty, Ludwig-Maximilians-University, 82152 München, Germany.
Illig C; Biomedical Center (BMC), Department for Cell Biology & Anatomy, Medical Faculty, Ludwig-Maximilians-University, 82152 München, Germany.
Saccà B; Zentrum für Medizinische Biotechnologie (ZMB), University of Duisburg-Essen, 41541 Duisburg, Germany.
Popper B; Biomedical Center (BMC), Department for Cell Biology & Anatomy, Medical Faculty, Ludwig-Maximilians-University, 82152 München, Germany.; Biomedical Center (BMC), Core Facility Animal Models, Ludwig-Maximilians-University, 82152 München, Germany.
Kiebler MA; Biomedical Center (BMC), Department for Cell Biology & Anatomy, Medical Faculty, Ludwig-Maximilians-University, 82152 München, Germany.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 20; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 20.
Typ publikacji :
Journal Article
MeSH Terms :
Eukaryotic Initiation Factor-4E/*metabolism
Neurons/*metabolism
RNA-Binding Proteins/*metabolism
Animals ; Eukaryotic Initiation Factor-4E/genetics ; Female ; Fibroblast Growth Factor 2/metabolism ; Gene Expression/genetics ; Male ; Mice ; Mice, Inbred C57BL ; Microscopy, Atomic Force/methods ; Neurogenesis/physiology ; Protein Binding/physiology ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; RNA-Binding Proteins/genetics ; Transcriptome/genetics
Czasopismo naukowe
Tytuł :
Spatiotemporally-resolved mapping of RNA binding proteins via functional proximity labeling reveals a mitochondrial mRNA anchor promoting stress recovery.
Autorzy :
Qin W; Departments of Biology, Genetics, and Chemistry, Stanford University, Stanford, CA, USA.; Chan Zuckerberg Biohub, San Francisco, CA, USA.
Myers SA; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; La Jolla Institute for Immunology, La Jolla, CA, USA.
Carey DK; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Carr SA; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Ting AY; Departments of Biology, Genetics, and Chemistry, Stanford University, Stanford, CA, USA. .; Chan Zuckerberg Biohub, San Francisco, CA, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 Aug 17; Vol. 12 (1), pp. 4980. Date of Electronic Publication: 2021 Aug 17.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
RNA, Messenger/*metabolism
RNA, Mitochondrial/*metabolism
RNA-Binding Proteins/*metabolism
Gene Knockout Techniques ; HEK293 Cells ; Humans ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Mitochondria/metabolism ; Mitochondrial Membranes/metabolism ; Phosphorylation ; Proteome/metabolism ; Proteomics ; RNA, Messenger/genetics ; RNA-Binding Proteins/genetics
Czasopismo naukowe

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