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Wyszukujesz frazę ""RNA-Seq"" wg kryterium: Temat


Tytuł :
RCA2: a scalable supervised clustering algorithm that reduces batch effects in scRNA-seq data.
Autorzy :
Schmidt F; Laboratory of Systems Biology and Data Analytics, Genome Institute of Singapore, A*STAR, 60 Biopolis St, 138672, Singapore.
Ranjan B; Laboratory of Systems Biology and Data Analytics, Genome Institute of Singapore, A*STAR, 60 Biopolis St, 138672, Singapore.
Lin QXX; Laboratory of Systems Biology and Data Analytics, Genome Institute of Singapore, A*STAR, 60 Biopolis St, 138672, Singapore.
Krishnan V; DUKE-NUS Medical School, 8 College Rd, 169857, Singapore.
Joanito I; Laboratory of Systems Biology and Data Analytics, Genome Institute of Singapore, A*STAR, 60 Biopolis St, 138672, Singapore.
Honardoost MA; Laboratory of Systems Biology and Data Analytics, Genome Institute of Singapore, A*STAR, 60 Biopolis St, 138672, Singapore.; Department of Medicine, School of Medicine, National University of Singapore, 1 Kent Ridge Road, level 10, NUHS Tower Block, 119228, Singapore.
Nawaz Z; Laboratory of Systems Biology and Data Analytics, Genome Institute of Singapore, A*STAR, 60 Biopolis St, 138672, Singapore.
Venkatesh PN; Laboratory of Systems Biology and Data Analytics, Genome Institute of Singapore, A*STAR, 60 Biopolis St, 138672, Singapore.
Tan J; Laboratory of Systems Biology and Data Analytics, Genome Institute of Singapore, A*STAR, 60 Biopolis St, 138672, Singapore.
Rayan NA; Laboratory of Systems Biology and Data Analytics, Genome Institute of Singapore, A*STAR, 60 Biopolis St, 138672, Singapore.
Ong ST; DUKE-NUS Medical School, 8 College Rd, 169857, Singapore.; Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA.
Prabhakar S; Laboratory of Systems Biology and Data Analytics, Genome Institute of Singapore, A*STAR, 60 Biopolis St, 138672, Singapore.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2021 Sep 07; Vol. 49 (15), pp. 8505-8519.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Algorithms*
Cluster Analysis*
RNA, Small Cytoplasmic/*genetics
RNA-Seq/*methods
Single-Cell Analysis/*methods
Animals ; Arthritis, Rheumatoid/genetics ; Bone Marrow Cells/metabolism ; COVID-19/blood ; COVID-19/pathology ; Cohort Studies ; Datasets as Topic ; Humans ; Leukocytes, Mononuclear/metabolism ; Leukocytes, Mononuclear/pathology ; Mice ; Organ Specificity ; Quality Control ; RNA-Seq/standards ; Single-Cell Analysis/standards ; Transcriptome
Czasopismo naukowe
Tytuł :
Cross-species integration of single-cell RNA-seq resolved alveolar-epithelial transitional states in idiopathic pulmonary fibrosis.
Autorzy :
Huang KY; Program in Cardiovascular and Metabolic Disorders (CVMD) and Center for Computational Biology (CCB), Duke-NUS Medical School, Singapore, Republic of Singapore.
Petretto E; Program in Cardiovascular and Metabolic Disorders (CVMD) and Center for Computational Biology (CCB), Duke-NUS Medical School, Singapore, Republic of Singapore.
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Źródło :
American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2021 Sep 01; Vol. 321 (3), pp. L491-L506. Date of Electronic Publication: 2021 Jun 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation*
Idiopathic Pulmonary Fibrosis*/genetics
Idiopathic Pulmonary Fibrosis*/metabolism
Idiopathic Pulmonary Fibrosis*/pathology
RNA-Seq*
Single-Cell Analysis*
Alveolar Epithelial Cells/*metabolism
Respiratory Mucosa/*metabolism
Alveolar Epithelial Cells/pathology ; Animals ; Disease Models, Animal ; Humans ; Mice ; Mice, Knockout ; Respiratory Mucosa/pathology ; Species Specificity
Czasopismo naukowe
Tytuł :
Adaptive Total-Variation Regularized Low-Rank Representation for Analyzing Single-Cell RNA-seq Data.
Autorzy :
Liu JX; School of Computer Science, Qufu Normal University, Rizhao, China.
Wang CY; School of Computer Science, Qufu Normal University, Rizhao, China.
Gao YL; Qufu Normal University Library, Qufu Normal University, Rizhao, China.
Zhang Y; College of Mathematics and Systems Science, Shandong University of Science and Technology, Qingdao, China.
Wang J; School of Computer Science, Qufu Normal University, Rizhao, China. .
Li SJ; School of Computer Science, Qufu Normal University, Rizhao, China.
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Źródło :
Interdisciplinary sciences, computational life sciences [Interdiscip Sci] 2021 Sep; Vol. 13 (3), pp. 476-489. Date of Electronic Publication: 2021 Jun 02.
Typ publikacji :
Journal Article
MeSH Terms :
RNA-Seq*
Algorithms ; Cluster Analysis ; Gene Expression Profiling ; Single-Cell Analysis
Czasopismo naukowe
Tytuł :
Identification and validation of 12 immune-related genes as a prognostic signature for colon adenocarcinoma.
Autorzy :
Tang D; The First Affiliated Hospital, Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou, China.
Huang W; The Third Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Yang Z; The First Affiliated Hospital, Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou, China.
Wu X; School of Pharmacy, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Sang X; School of Pharmacy, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Wang K; School of Pharmacy, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Cao G; School of Pharmacy, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
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Źródło :
Journal of biochemical and molecular toxicology [J Biochem Mol Toxicol] 2021 Sep; Vol. 35 (9), pp. e22852. Date of Electronic Publication: 2021 Aug 15.
Typ publikacji :
Journal Article; Validation Study
MeSH Terms :
Adenocarcinoma*/genetics
Adenocarcinoma*/metabolism
Adenocarcinoma*/mortality
Colonic Neoplasms*/genetics
Colonic Neoplasms*/metabolism
Colonic Neoplasms*/mortality
Databases, Nucleic Acid*
Gene Expression Regulation, Neoplastic*
RNA-Seq*
Disease-Free Survival ; Female ; Humans ; Male ; Survival Rate
Czasopismo naukowe
Tytuł :
M2 macrophages have unique transcriptomes but conditioned media does not promote profibrotic responses in lung fibroblasts or alveolar epithelial cells in vitro.
Autorzy :
Hult EM; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan.
Gurczynski SJ; Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan.
Moore BB; Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan.; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
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Źródło :
American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2021 Sep 01; Vol. 321 (3), pp. L518-L532. Date of Electronic Publication: 2021 Jul 07.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation*
RNA-Seq*
Alveolar Epithelial Cells/*metabolism
Fibroblasts/*metabolism
Macrophages/*metabolism
Pulmonary Fibrosis/*metabolism
Alveolar Epithelial Cells/pathology ; Animals ; Coculture Techniques ; Culture Media, Conditioned/pharmacology ; Female ; Fibroblasts/pathology ; Macrophages/pathology ; Male ; Mice ; Mice, Transgenic ; Pulmonary Fibrosis/genetics ; Pulmonary Fibrosis/pathology
Czasopismo naukowe
Tytuł :
Cholesterol efflux pathways, inflammation, and atherosclerosis.
Autorzy :
Groenen AG; Department of Pediatrics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Halmos B; Department of Pediatrics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Tall AR; Division of Molecular Medicine, Department of Medicine, Columbia University, New York, NY, USA.
Westerterp M; Department of Pediatrics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
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Źródło :
Critical reviews in biochemistry and molecular biology [Crit Rev Biochem Mol Biol] 2021 Aug; Vol. 56 (4), pp. 426-439. Date of Electronic Publication: 2021 Jun 28.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review; Video-Audio Media
MeSH Terms :
Gene Expression Regulation*
RNA-Seq*
Single-Cell Analysis*
Atherosclerosis/*metabolism
Cholesterol, HDL/*metabolism
Animals ; Atherosclerosis/genetics ; Atherosclerosis/pathology ; Biological Transport, Active/genetics ; Cell Proliferation ; Cholesterol, HDL/genetics ; Hematopoietic Stem Cells/metabolism ; Hematopoietic Stem Cells/pathology ; Humans ; Inflammasomes ; Inflammation/genetics ; Inflammation/metabolism ; Inflammation/pathology ; Liver X Receptors/genetics ; Liver X Receptors/metabolism ; Mendelian Randomization Analysis
Czasopismo naukowe
Tytuł :
Applications of single-cell and bulk RNA sequencing in onco-immunology.
Autorzy :
Kuksin M; ENS de Lyon, 15 Parvis René Descartes, 69007, Lyon, France; Département d'Innovations Thérapeutiques et Essais Précoces (DITEP), Gustave Roussy Cancer Campus, 114 rue Edouard Vaillant, 94800, Villejuif, France.
Morel D; Département d'Innovations Thérapeutiques et Essais Précoces (DITEP), Gustave Roussy Cancer Campus, 114 rue Edouard Vaillant, 94800, Villejuif, France; Département de Radiothérapie, Gustave Roussy Cancer Campus, Gustave Roussy, 114 rue Edouard Vaillant, 94800, Villejuif, France; INSERM UMR1030, Molecular Radiotherapy and Therapeutic Innovations, Gustave Roussy, 114 rue Edouard Vaillant, 94800, Villejuif, France.
Aglave M; INSERM US23, CNRS UMS 3655, Gustave Roussy Cancer Campus, 114 rue Edouard Vaillant, 94800, Villejuif, France.
Danlos FX; INSERM U1015, Gustave Roussy, Université Paris Saclay, France.
Marabelle A; Département d'Innovations Thérapeutiques et Essais Précoces (DITEP), Gustave Roussy Cancer Campus, 114 rue Edouard Vaillant, 94800, Villejuif, France; INSERM U1015, Gustave Roussy, Université Paris Saclay, France.
Zinovyev A; Institut Curie, PSL Research University, F-75005, Paris, France; INSERM, U900, F-75005, Paris, France; MINES ParisTech, PSL Research University, CBIO-Centre for Computational Biology, F-75006, Paris, France; Laboratory of Advanced Methods for High-dimensional Data Analysis, Lobachevsky University, 603000, Nizhny Novgorod, Russia.
Gautheret D; Institute for Integrative Biology of the Cell, UMR 9198, CEA, CNRS, Université Paris-Saclay, Gif-Sur-Yvette, France; IHU PRISM, Gustave Roussy Cancer Campus, Gustave Roussy, 114 Rue Edouard Vaillant, 94800, Villejuif, France; Université Paris-Saclay, France.
Verlingue L; Département d'Innovations Thérapeutiques et Essais Précoces (DITEP), Gustave Roussy Cancer Campus, 114 rue Edouard Vaillant, 94800, Villejuif, France; INSERM UMR1030, Molecular Radiotherapy and Therapeutic Innovations, Gustave Roussy, 114 rue Edouard Vaillant, 94800, Villejuif, France; Institut Curie, PSL Research University, F-75005, Paris, France; Université Paris-Saclay, France. Electronic address: .
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Źródło :
European journal of cancer (Oxford, England : 1990) [Eur J Cancer] 2021 May; Vol. 149, pp. 193-210. Date of Electronic Publication: 2021 Apr 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Gene Expression Profiling*
RNA-Seq*
Single-Cell Analysis*
Transcriptome*
Biomarkers, Tumor/*genetics
Neoplasms/*genetics
Neoplasms/*immunology
RNA, Neoplasm/*genetics
Tumor Microenvironment/*immunology
Artificial Intelligence ; Clinical Decision-Making ; Humans ; Neoplasms/drug therapy ; Neoplasms/pathology ; Precision Medicine ; Predictive Value of Tests ; Prognosis
Czasopismo naukowe
Tytuł :
Comparative Transcriptome Analysis of Human Adipose-Derived Stem Cells Undergoing Osteogenesis in 2D and 3D Culture Conditions.
Autorzy :
Kim BC; Department of Dentistry, Graduate School, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Korea.
Kwack KH; Department of Dentistry, Graduate School, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Korea.
Chun J; Department of Dentistry, Graduate School, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Korea.
Lee JH; Department of Oral Microbiology, School of Dentistry, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Korea.; Department of Life and Nanopharmaceutical Sciences, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Korea.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 26; Vol. 22 (15). Date of Electronic Publication: 2021 Jul 26.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Cell Culture Techniques*
Osteogenesis*
RNA-Seq*
Adipose Tissue/*metabolism
Stem Cells/*metabolism
Adipose Tissue/cytology ; Humans ; Stem Cells/cytology
Czasopismo naukowe
Tytuł :
Transcriptome analysis of gene expression changes upon enzymatic dissociation in skeletal myoblasts.
Autorzy :
Miyawaki-Kuwakado A; Division of Transcriptomics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
Wu Q; Division of Transcriptomics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
Harada A; Division of Transcriptomics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
Tomimatsu K; Division of Transcriptomics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
Fujii T; Division of Transcriptomics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
Maehara K; Division of Transcriptomics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
Ohkawa Y; Division of Transcriptomics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
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Źródło :
Genes to cells : devoted to molecular & cellular mechanisms [Genes Cells] 2021 Jul; Vol. 26 (7), pp. 530-540. Date of Electronic Publication: 2021 Jun 08.
Typ publikacji :
Journal Article
MeSH Terms :
Transcriptome*
Myoblasts/*metabolism
RNA-Seq/*methods
Animals ; Cell Line ; Mice ; Myoblasts/drug effects ; NIH 3T3 Cells ; RNA-Seq/standards ; Trypsin/pharmacology
Czasopismo naukowe
Tytuł :
An Easy, Cost-Effective, and Scalable Method to Deplete Human Ribosomal RNA for RNA-seq.
Autorzy :
Baldwin A; University of Colorado Anschutz School of Medicine, Aurora, Colorado.
Morris AR; Independent researcher, Rougemont, North Carolina.
Mukherjee N; University of Colorado Anschutz School of Medicine, Aurora, Colorado.
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Źródło :
Current protocols [Curr Protoc] 2021 Jun; Vol. 1 (6), pp. e176.
Typ publikacji :
Journal Article
MeSH Terms :
RNA, Ribosomal*/genetics
RNA-Seq*
Transcriptome*
Cost-Benefit Analysis ; Humans ; RNA, Messenger
Czasopismo naukowe
Tytuł :
RNA-seq-Based Screening in Coal Dust-Treated Cells Identified PHLDB2 as a Novel Lung Cancer-Related Molecular Marker.
Autorzy :
Ge D; Key Laboratory of Industrial Dust Prevention and Control & Occupational Health and Safety, Ministry of Education (Anhui University of Science and Technology), China.; Anhui Province Engineering Laboratory of Occupational Health and Safety, China.; School of Medicine, Anhui University of Science and Technology, No. 168 Taifeng Road, Huainan, Anhui Province, China.
Shao Y; School of Medicine, Anhui University of Science and Technology, No. 168 Taifeng Road, Huainan, Anhui Province, China.
Wang M; School of Medicine, Anhui University of Science and Technology, No. 168 Taifeng Road, Huainan, Anhui Province, China.
Tao H; Key Laboratory of Industrial Dust Prevention and Control & Occupational Health and Safety, Ministry of Education (Anhui University of Science and Technology), China.; Anhui Province Engineering Laboratory of Occupational Health and Safety, China.; School of Medicine, Anhui University of Science and Technology, No. 168 Taifeng Road, Huainan, Anhui Province, China.
Mu M; Key Laboratory of Industrial Dust Prevention and Control & Occupational Health and Safety, Ministry of Education (Anhui University of Science and Technology), China.; Anhui Province Engineering Laboratory of Occupational Health and Safety, China.; School of Medicine, Anhui University of Science and Technology, No. 168 Taifeng Road, Huainan, Anhui Province, China.
Tao X; Key Laboratory of Industrial Dust Prevention and Control & Occupational Health and Safety, Ministry of Education (Anhui University of Science and Technology), China.; Anhui Province Engineering Laboratory of Occupational Health and Safety, China.; School of Medicine, Anhui University of Science and Technology, No. 168 Taifeng Road, Huainan, Anhui Province, China.
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Źródło :
BioMed research international [Biomed Res Int] 2021 Jul 19; Vol. 2021, pp. 1978434. Date of Electronic Publication: 2021 Jul 19 (Print Publication: 2021).
Typ publikacji :
Journal Article
MeSH Terms :
Coal*
Dust*
Early Detection of Cancer*
RNA-Seq*
Biomarkers, Tumor/*genetics
Carrier Proteins/*genetics
Lung Neoplasms/*diagnosis
Lung Neoplasms/*genetics
Animals ; Biomarkers, Tumor/metabolism ; Carrier Proteins/metabolism ; Cell Death/genetics ; Cell Survival/genetics ; Epithelial-Mesenchymal Transition/genetics ; Gene Expression Regulation, Neoplastic ; Humans ; Lung Neoplasms/pathology ; Mice ; RAW 264.7 Cells ; Survival Analysis
Czasopismo naukowe
Tytuł :
Host-Virus Chimeric Events in SARS-CoV-2-Infected Cells Are Infrequent and Artifactual.
Autorzy :
Yan B; Department of Biochemistry, Purdue University, West Lafayette, Indiana, USA.
Chakravorty S; Department of Biochemistry, Purdue University, West Lafayette, Indiana, USA.
Mirabelli C; Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, USA.
Wang L; Department of Computer Science, Purdue University, West Lafayette, Indiana, USA.
Trujillo-Ochoa JL; Immunoregulation Section, Kidney Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), NIH, Bethesda, Maryland, USA.
Chauss D; Immunoregulation Section, Kidney Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), NIH, Bethesda, Maryland, USA.
Kumar D; Department of Biochemistry, Purdue University, West Lafayette, Indiana, USA.; Immunoregulation Section, Kidney Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), NIH, Bethesda, Maryland, USA.
Lionakis MS; Fungal Pathogenesis Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, Maryland, USA.
Olson MR; Department of Biological Sciences, Purdue University, West Lafayette, Indiana, USA.
Wobus CE; Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, USA.
Afzali B; Immunoregulation Section, Kidney Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), NIH, Bethesda, Maryland, USA.
Kazemian M; Department of Biochemistry, Purdue University, West Lafayette, Indiana, USA.; Department of Computer Science, Purdue University, West Lafayette, Indiana, USA.
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Źródło :
Journal of virology [J Virol] 2021 Jul 12; Vol. 95 (15), pp. e0029421. Date of Electronic Publication: 2021 Jul 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Host-Pathogen Interactions*
RNA-Seq*
Virus Replication*
COVID-19/*metabolism
RNA, Viral/*metabolism
SARS-CoV-2/*physiology
COVID-19/genetics ; COVID-19/pathology ; Cell Line, Tumor ; Humans ; RNA, Viral/genetics
Czasopismo naukowe
Tytuł :
TIMEOR: a web-based tool to uncover temporal regulatory mechanisms from multi-omics data.
Autorzy :
Conard AM; Computer Science Department, Brown University, Providence, RI 02912, USA.; Center for Computational and Molecular Biology, Brown University, Providence, RI 02912, USA.
Goodman N; Computer Science Department, Brown University, Providence, RI 02912, USA.
Hu Y; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.; Director of Bioinformatics DRSC/TRiP Functional Genomics Resources, Harvard Medical School, Boston, MA 02115, USA.
Perrimon N; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.; Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02115, USA.
Singh R; Computer Science Department, Brown University, Providence, RI 02912, USA.; Center for Computational and Molecular Biology, Brown University, Providence, RI 02912, USA.
Lawrence C; Center for Computational and Molecular Biology, Brown University, Providence, RI 02912, USA.; Applied Math Department, Brown University, Providence, RI 02912, USA.
Larschan E; Center for Computational and Molecular Biology, Brown University, Providence, RI 02912, USA.; Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, RI 02912, USA.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2021 Jul 02; Vol. 49 (W1), pp. W641-W653.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Validation Study
MeSH Terms :
Gene Expression Regulation*
Gene Regulatory Networks*
RNA-Seq*
Software*
Circadian Rhythm/genetics ; Genomics ; Humans ; Insulin/physiology ; Internet ; Protein Interaction Mapping ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł :
Single-cell RNA sequencing identify SDCBP in ACE2-positive bronchial epithelial cells negatively correlates with COVID-19 severity.
Autorzy :
Ma D; Jiangsu Key Laboratory of Molecular Medicine, National Institute of Healthcare Data Science at Nanjing University, Medical School of Nanjing University, Nanjing, China.; Department of Hepatobiliary Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.
Liu S; Jiangsu Key Laboratory of Molecular Medicine, National Institute of Healthcare Data Science at Nanjing University, Medical School of Nanjing University, Nanjing, China.
Hu L; Jiangsu Key Laboratory of Molecular Medicine, National Institute of Healthcare Data Science at Nanjing University, Medical School of Nanjing University, Nanjing, China.; Department of Hepatobiliary Surgery, Drum Tower Clinical College of Nanjing Medical University, Nanjing, China.
He Q; Jiangsu Key Laboratory of Molecular Medicine, National Institute of Healthcare Data Science at Nanjing University, Medical School of Nanjing University, Nanjing, China.
Shi W; Jiangsu Key Laboratory of Molecular Medicine, National Institute of Healthcare Data Science at Nanjing University, Medical School of Nanjing University, Nanjing, China.; Department of Hepatobiliary Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.
Yan D; Jiangsu Key Laboratory of Molecular Medicine, National Institute of Healthcare Data Science at Nanjing University, Medical School of Nanjing University, Nanjing, China.; Department of Hepatobiliary Surgery, Drum Tower Clinical College of Nanjing Medical University, Nanjing, China.
Cao Y; Jiangsu Key Laboratory of Molecular Medicine, National Institute of Healthcare Data Science at Nanjing University, Medical School of Nanjing University, Nanjing, China.; Department of Hepatobiliary Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.; Department of Hepatobiliary Surgery, Drum Tower Clinical College of Nanjing Medical University, Nanjing, China.
Zhang G; Jiangsu Key Laboratory of Molecular Medicine, National Institute of Healthcare Data Science at Nanjing University, Medical School of Nanjing University, Nanjing, China.; Department of Hepatobiliary Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.; Department of Hepatobiliary Surgery, Drum Tower Clinical College of Nanjing Medical University, Nanjing, China.
Wang Z; Jiangsu Key Laboratory of Molecular Medicine, National Institute of Healthcare Data Science at Nanjing University, Medical School of Nanjing University, Nanjing, China.; Department of Hepatobiliary Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.; Department of Hepatobiliary Surgery, Drum Tower Clinical College of Nanjing Medical University, Nanjing, China.
Wu J; Jiangsu Key Laboratory of Molecular Medicine, National Institute of Healthcare Data Science at Nanjing University, Medical School of Nanjing University, Nanjing, China.
Jiang C; Jiangsu Key Laboratory of Molecular Medicine, National Institute of Healthcare Data Science at Nanjing University, Medical School of Nanjing University, Nanjing, China.; Department of Hepatobiliary Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.; Department of Hepatobiliary Surgery, Drum Tower Clinical College of Nanjing Medical University, Nanjing, China.
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Źródło :
Journal of cellular and molecular medicine [J Cell Mol Med] 2021 Jul; Vol. 25 (14), pp. 7001-7012. Date of Electronic Publication: 2021 Jun 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
RNA-Seq*
Severity of Illness Index*
Single-Cell Analysis*
Angiotensin-Converting Enzyme 2/*metabolism
Bronchi/*pathology
COVID-19/*pathology
Epithelial Cells/*metabolism
Syntenins/*metabolism
Antigen Presentation/genetics ; Bronchoalveolar Lavage Fluid ; COVID-19/genetics ; COVID-19/metabolism ; Epithelial Cells/pathology ; Gene Expression Profiling ; Humans ; Postmortem Changes ; SARS-CoV-2/physiology ; Up-Regulation/genetics
Czasopismo naukowe
Tytuł :
High-throughput full-length single-cell RNA-seq automation.
Autorzy :
Mamanova L; Wellcome Sanger Institute, Cambridge, UK. .
Miao Z; Wellcome Sanger Institute, Cambridge, UK.; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridge, UK.
Jinat A; Wellcome Sanger Institute, Cambridge, UK.
Ellis P; Wellcome Sanger Institute, Cambridge, UK.
Shirley L; Wellcome Sanger Institute, Cambridge, UK.
Teichmann SA; Wellcome Sanger Institute, Cambridge, UK. .; Department of Physics, Cavendish Laboratory, University of Cambridge, Cambridge, UK. .
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Źródło :
Nature protocols [Nat Protoc] 2021 Jun; Vol. 16 (6), pp. 2886-2915. Date of Electronic Publication: 2021 May 14.
Typ publikacji :
Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Automation, Laboratory*
RNA-Seq*
Single-Cell Analysis*
Animals ; Mice
Czasopismo naukowe
Tytuł :
Bone marrow mesenchymal stromal cells in chronic myelomonocytic leukaemia: overactivated WNT/β-catenin signalling by parallel RNA sequencing and dysfunctional phenotypes.
Autorzy :
Xu R; Department of Hematology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine, South China University of Technology, Guangzhou, Guangdong, 510080, P.R. China.
Huang X; Department of Hematology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine, South China University of Technology, Guangzhou, Guangdong, 510080, P.R. China.
Li C; Department of Hematology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine, South China University of Technology, Guangzhou, Guangdong, 510080, P.R. China.
Deng C; Department of Hematology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine, South China University of Technology, Guangzhou, Guangdong, 510080, P.R. China.
Li M; Department of Hematology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine, South China University of Technology, Guangzhou, Guangdong, 510080, P.R. China.
Wu P; Department of Hematology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine, South China University of Technology, Guangzhou, Guangdong, 510080, P.R. China.
Geng S; Department of Hematology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine, South China University of Technology, Guangzhou, Guangdong, 510080, P.R. China.
Lai P; Department of Hematology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine, South China University of Technology, Guangzhou, Guangdong, 510080, P.R. China.
Lu Z; Department of Hematology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine, South China University of Technology, Guangzhou, Guangdong, 510080, P.R. China.
Weng J; Department of Hematology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine, South China University of Technology, Guangzhou, Guangdong, 510080, P.R. China.
Du X; Department of Hematology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine, South China University of Technology, Guangzhou, Guangdong, 510080, P.R. China.
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Źródło :
British journal of haematology [Br J Haematol] 2021 Jun; Vol. 193 (5), pp. 928-940. Date of Electronic Publication: 2021 May 06.
Typ publikacji :
Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Leukemic*
Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/drug therapy
Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/genetics
Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/metabolism
Neoplasm Proteins*/biosynthesis
Neoplasm Proteins*/genetics
RNA-Seq*
Bone Marrow Cells/*metabolism
Mesenchymal Stem Cells/*metabolism
Wnt Signaling Pathway/*genetics
Adult ; Aged ; Female ; Hematopoietic Stem Cells/metabolism ; Humans ; Male ; Middle Aged
Czasopismo naukowe
Tytuł :
RNA-seq reveals plant virus composition and diversity in alfalfa, thrips, and aphids in Beijing, China.
Autorzy :
Li J; College of Grassland Science and Technology, China Agricultural University, Beijing, China.
Gu H; College of Animal Science and Technology, China Agricultural University, Beijing, China.
Liu Y; College of Grassland Science and Technology, China Agricultural University, Beijing, China.
Wei S; Ningxia Academy of Agriculture and Forestry Sciences, Institute of Plant Protection, Yinchuan, Ningxia, China.
Hu G; Pratacultural College, Gansu Agricultural University, Lanzhou, Gansu, China.
Wang X; Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.
McNeill MR; AgResearch, Resilient Agriculture Innovative Centre of Excellence, Lincoln, New Zealand.
Ban L; College of Grassland Science and Technology, China Agricultural University, Beijing, China. .
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Źródło :
Archives of virology [Arch Virol] 2021 Jun; Vol. 166 (6), pp. 1711-1722. Date of Electronic Publication: 2021 Apr 17.
Typ publikacji :
Journal Article
MeSH Terms :
RNA-Seq*
Aphids/*virology
Medicago sativa/*virology
Plant Viruses/*isolation & purification
Thysanoptera/*virology
Animals ; China ; Plant Viruses/classification ; Plant Viruses/genetics ; RNA, Viral/genetics
Czasopismo naukowe
Tytuł :
Comprehensive Comparison of RNA-Seq Data of SARS-CoV-2, SARS-CoV and MERS-CoV Infections: Alternative Entry Routes and Innate Immune Responses.
Autorzy :
Cao Y; Bioinformatics and Computational Biophysics, Faculty of Biology and Center for Medical Biotechnology (ZMB), University of Duisburg-Essen, Essen, Germany.
Xu X; Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Shanghai, China.
Kitanovski S; Bioinformatics and Computational Biophysics, Faculty of Biology and Center for Medical Biotechnology (ZMB), University of Duisburg-Essen, Essen, Germany.
Song L; Department of Dermatology, University Hospital Essen, Essen, Germany.; Department of Translational Skin Cancer Research (TSCR), German Cancer Consortium (DKTK), Partner Site Essen, German Cancer Research Center, Heidelberg, Germany.
Wang J; Bioinformatics and Computational Biophysics, Faculty of Biology and Center for Medical Biotechnology (ZMB), University of Duisburg-Essen, Essen, Germany.
Hao P; Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Shanghai, China.
Hoffmann D; Bioinformatics and Computational Biophysics, Faculty of Biology and Center for Medical Biotechnology (ZMB), University of Duisburg-Essen, Essen, Germany.
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Źródło :
Frontiers in immunology [Front Immunol] 2021 May 28; Vol. 12, pp. 656433. Date of Electronic Publication: 2021 May 28 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
RNA, Viral*
RNA-Seq*
COVID-19/*virology
Coronavirus Infections/*virology
Middle East Respiratory Syndrome Coronavirus/*genetics
SARS Virus/*genetics
SARS-CoV-2/*genetics
COVID-19/immunology ; Cell Line ; Cells, Cultured ; Coronavirus Infections/immunology ; Host-Pathogen Interactions/immunology ; Humans ; Immunity, Innate ; Middle East Respiratory Syndrome Coronavirus/immunology ; SARS Virus/immunology ; SARS-CoV-2/immunology ; Virus Internalization
Czasopismo naukowe
Tytuł :
Generative modeling of single-cell time series with PRESCIENT enables prediction of cell trajectories with interventions.
Autorzy :
Yeo GHT; Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA, USA.; Computational and Systems Biology Program, Massachusetts Institute of Technology, Cambridge, MA, USA.
Saksena SD; Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA, USA.; Computational and Systems Biology Program, Massachusetts Institute of Technology, Cambridge, MA, USA.
Gifford DK; Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA, USA. .; Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, USA. .; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 May 28; Vol. 12 (1), pp. 3222. Date of Electronic Publication: 2021 May 28.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Models, Genetic*
RNA-Seq*
Cell Differentiation/*genetics
Single-Cell Analysis/*methods
Animals ; Cell Proliferation/genetics ; Cells, Cultured ; Computer Simulation ; Datasets as Topic ; Deep Learning ; Hematopoiesis/genetics ; Humans ; Insulin-Secreting Cells/physiology ; Mice ; Software ; Stem Cells/physiology ; Stochastic Processes
Czasopismo naukowe
Tytuł :
Transcriptional Cascade in the Regulation of Flowering in the Bamboo Orchid Arundina graminifolia .
Autorzy :
Ahmad S; Guangdong Key Laboratory of Ornamental Plant Germplasm Innovation and Utilization, Environmental Horticulture Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China.
Lu C; Guangdong Key Laboratory of Ornamental Plant Germplasm Innovation and Utilization, Environmental Horticulture Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China.
Wu J; Guangdong Key Laboratory of Ornamental Plant Germplasm Innovation and Utilization, Environmental Horticulture Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China.
Wei Y; Guangdong Key Laboratory of Ornamental Plant Germplasm Innovation and Utilization, Environmental Horticulture Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China.
Gao J; Guangdong Key Laboratory of Ornamental Plant Germplasm Innovation and Utilization, Environmental Horticulture Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China.
Jin J; Guangdong Key Laboratory of Ornamental Plant Germplasm Innovation and Utilization, Environmental Horticulture Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China.
Zheng C; Guangdong Key Laboratory of Ornamental Plant Germplasm Innovation and Utilization, Environmental Horticulture Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China.
Zhu G; Guangdong Key Laboratory of Ornamental Plant Germplasm Innovation and Utilization, Environmental Horticulture Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China.
Yang F; Guangdong Key Laboratory of Ornamental Plant Germplasm Innovation and Utilization, Environmental Horticulture Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China.
Pokaż więcej
Źródło :
Biomolecules [Biomolecules] 2021 May 21; Vol. 11 (6). Date of Electronic Publication: 2021 May 21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation, Plant*
RNA-Seq*
Transcription, Genetic*
Flowers/*metabolism
Orchidaceae/*metabolism
Plant Proteins/*biosynthesis
Flowers/genetics ; Orchidaceae/genetics ; Plant Proteins/genetics
Czasopismo naukowe

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