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Wyświetlanie 1-20 z 2571
Tytuł:
Deciphering the potential ability of RG108 in cisplatin-induced HEI-OC1 ototoxicity: a research based on RNA-seq and molecular biology experiment.
Autorzy:
Zhang D; Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Zhongshan Hospital, Xiamen University, Xiamen, 361003, China.; School of Medicine, Xiamen University, Xiamen, 361003, China.
Sun Y; School of Medicine, Xiamen University, Xiamen, 361003, China.; Department of Surgery, The Second People's Hospital of Neijiang Affiliated to Southwest Medical University, Neijiang, 641000, China.; Department of Surgery, The Second People's Hospital of Neijiang, Neijiang, 641000, China.
Lei M; Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Zhongshan Hospital, Xiamen University, Xiamen, 361003, China.; School of Medicine, Xiamen University, Xiamen, 361003, China.
Wang Y; Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Zhongshan Hospital, Xiamen University, Xiamen, 361003, China.
Cai C; Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Zhongshan Hospital, Xiamen University, Xiamen, 361003, China. .; School of Medicine, Xiamen University, Xiamen, 361003, China. .
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Źródło:
Hereditas [Hereditas] 2023 Apr 24; Vol. 160 (1), pp. 18. Date of Electronic Publication: 2023 Apr 24.
Typ publikacji:
Journal Article
MeSH Terms:
Antineoplastic Agents*/toxicity
Ototoxicity*/etiology
Hearing Loss*/chemically induced
Hearing Loss*/genetics
Humans ; Cisplatin/toxicity ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-akt/metabolism ; Reactive Oxygen Species/metabolism ; Phosphatidylinositol 3-Kinases/genetics ; Phosphatidylinositol 3-Kinases/pharmacology ; NF-E2-Related Factor 2/genetics ; NF-E2-Related Factor 2/metabolism ; NF-E2-Related Factor 2/pharmacology ; RNA-Seq ; Cell Line ; Apoptosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Association between particulate matter containing EPFRs and neutrophilic asthma through AhR and Th17.
Autorzy:
Harding JN; Department of Biological Sciences, Louisiana State University and Pennington Biomedical Research Center, 6400 Perkins Rd, Baton Rouge, LA, 70808, USA.
Gross M; Department of Biological Sciences, Louisiana State University and Pennington Biomedical Research Center, 6400 Perkins Rd, Baton Rouge, LA, 70808, USA.
Patel V; Department of Biological Sciences, Louisiana State University and Pennington Biomedical Research Center, 6400 Perkins Rd, Baton Rouge, LA, 70808, USA.
Potter S; Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, 3333 Burnet Avenue, Cincinnati, OH, 45229, USA.
Cormier SA; Department of Biological Sciences, Louisiana State University and Pennington Biomedical Research Center, 6400 Perkins Rd, Baton Rouge, LA, 70808, USA. .
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Źródło:
Respiratory research [Respir Res] 2021 Oct 26; Vol. 22 (1), pp. 275. Date of Electronic Publication: 2021 Oct 26.
Typ publikacji:
Journal Article
MeSH Terms:
Asthma/*chemically induced
Basic Helix-Loop-Helix Transcription Factors/*metabolism
Dendritic Cells/*drug effects
Epithelial Cells/*drug effects
Lung/*drug effects
Neutrophil Infiltration/*drug effects
Neutrophils/*drug effects
Particulate Matter/*toxicity
Receptors, Aryl Hydrocarbon/*metabolism
Th17 Cells/*drug effects
Animals ; Asthma/genetics ; Asthma/immunology ; Asthma/metabolism ; Basic Helix-Loop-Helix Transcription Factors/genetics ; Cytokines/genetics ; Cytokines/metabolism ; Dendritic Cells/immunology ; Dendritic Cells/metabolism ; Epithelial Cells/immunology ; Epithelial Cells/metabolism ; Female ; Gene Expression Profiling ; Lung/immunology ; Lung/metabolism ; Male ; Mice, Inbred C57BL ; Neutrophils/immunology ; Neutrophils/metabolism ; RNA-Seq ; Receptors, Aryl Hydrocarbon/genetics ; Signal Transduction ; Single-Cell Analysis ; Th17 Cells/immunology ; Th17 Cells/metabolism ; Transcriptome ; Mice
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
RNA-Seq based transcriptome analysis in oral lichen planus.
Autorzy:
Wang H; Department of Dermatology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Deng Y; Department of Oral Mucosal Diseases, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, Shanghai, China.
Peng S; Shanghai Key Laboratory of Compound Chinese Medicines, The MOE Key Laboratory for Standardization of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Yan L; Department of Dermatology, Shanghai Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xu H; Department of Dermatology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wang Q; Shanghai Key Laboratory of Compound Chinese Medicines, The MOE Key Laboratory for Standardization of Chinese Medicines, Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, China. .
Shen Z; Department of Dermatology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. .
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Źródło:
Hereditas [Hereditas] 2021 Oct 06; Vol. 158 (1), pp. 39. Date of Electronic Publication: 2021 Oct 06.
Typ publikacji:
Journal Article
MeSH Terms:
Lichen Planus, Oral*/genetics
Computational Biology ; Gene Expression Profiling ; Humans ; RNA-Seq ; Sequence Analysis, RNA ; Transcriptome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Regulation of DNA methylation on key parasitism genes of Cysticercus cellulosae revealed by integrative epigenomic-transcriptomic analyses.
Autorzy:
Wang X; College of Animal Science and Technology, Inner Mongolia University for Nationalities, Tongliao, 028000, Inner Mongolia, China.
Song W; College of Animal Science and Technology, Inner Mongolia University for Nationalities, Tongliao, 028000, Inner Mongolia, China.
Ji G; Shenzhen E-GENE Technology Co., LTD, B3301, Life Science Park, Shenzhen City Construction Investment Development Creative Factory, Julongshan A Road, Pingshan District, Shenzhen, 518083, China.
Song Y; College of Animal Science and Technology, Inner Mongolia University for Nationalities, Tongliao, 028000, Inner Mongolia, China.
Liu X; Key Laboratory of Zoonosis Research, Ministry of Education, Institute of Zoonosis, College of Veterinary Medicine, Jilin University, Changchun, 130000, China.
Luo X; Lanzhou Institute of Veterinary Medicine, Chinese Academy of Agricultural Sciences, Lanzhou, 730000, China.
Liu M; College of Animal Science and Technology, Inner Mongolia University for Nationalities, Tongliao, 028000, Inner Mongolia, China. .; Key Laboratory of Zoonosis Research, Ministry of Education, Institute of Zoonosis, College of Veterinary Medicine, Jilin University, Changchun, 130000, China. .
Sun S; College of Animal Science and Technology, Inner Mongolia University for Nationalities, Tongliao, 028000, Inner Mongolia, China. .
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Źródło:
Hereditas [Hereditas] 2021 Aug 12; Vol. 158 (1), pp. 28. Date of Electronic Publication: 2021 Aug 12.
Typ publikacji:
Journal Article
MeSH Terms:
DNA Methylation*
Genome, Helminth*
Taenia solium/*genetics
Animals ; Epigenomics ; Gene Expression Profiling ; Gene Expression Regulation ; RNA-Seq ; Whole Genome Sequencing
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Single-cell characterization of a model of poly I:C-stimulated peripheral blood mononuclear cells in severe asthma.
Autorzy:
Chen A; Section of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Yale University School of Medicine, 300 Cedar Street (S419 TAC), New Haven, CT, 06520-8057, USA.
Diaz-Soto MP; Section of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Yale University School of Medicine, 300 Cedar Street (S419 TAC), New Haven, CT, 06520-8057, USA.
Sanmamed MF; Department of Oncology, Clínica Universidad de Navarra, Pamplona, Spain.; Program of Immunology and Immunotherapy, Center for Applied Medical Research, University of Navarra, Pamplona, Spain.
Adams T; Section of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Yale University School of Medicine, 300 Cedar Street (S419 TAC), New Haven, CT, 06520-8057, USA.
Schupp JC; Section of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Yale University School of Medicine, 300 Cedar Street (S419 TAC), New Haven, CT, 06520-8057, USA.
Gupta A; Section of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Yale University School of Medicine, 300 Cedar Street (S419 TAC), New Haven, CT, 06520-8057, USA.
Britto C; Section of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Yale University School of Medicine, 300 Cedar Street (S419 TAC), New Haven, CT, 06520-8057, USA.
Sauler M; Section of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Yale University School of Medicine, 300 Cedar Street (S419 TAC), New Haven, CT, 06520-8057, USA.
Yan X; Section of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Yale University School of Medicine, 300 Cedar Street (S419 TAC), New Haven, CT, 06520-8057, USA.
Liu Q; Section of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Yale University School of Medicine, 300 Cedar Street (S419 TAC), New Haven, CT, 06520-8057, USA.
Nino G; Division of Pediatric Pulmonary and Sleep Medicine, Children's National Hospital, Department of Pediatrics, George Washington University, Washington, DC, USA.
Cruz CSD; Section of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Yale University School of Medicine, 300 Cedar Street (S419 TAC), New Haven, CT, 06520-8057, USA.
Chupp GL; Section of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Yale University School of Medicine, 300 Cedar Street (S419 TAC), New Haven, CT, 06520-8057, USA.
Gomez JL; Section of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Yale University School of Medicine, 300 Cedar Street (S419 TAC), New Haven, CT, 06520-8057, USA. .
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Źródło:
Respiratory research [Respir Res] 2021 Apr 26; Vol. 22 (1), pp. 122. Date of Electronic Publication: 2021 Apr 26.
Typ publikacji:
Journal Article
MeSH Terms:
Single-Cell Analysis*
Asthma/*immunology
Leukocytes, Mononuclear/*drug effects
Poly I-C/*pharmacology
Adult ; Asthma/diagnosis ; Asthma/genetics ; Case-Control Studies ; Cells, Cultured ; Female ; Flow Cytometry ; Gene Expression Profiling ; Humans ; Leukocytes, Mononuclear/immunology ; Leukocytes, Mononuclear/metabolism ; Male ; Middle Aged ; Phenotype ; RNA-Seq ; Severity of Illness Index ; Time Factors ; Transcriptome ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Transcriptome analysis on responses of orchardgrass (Dactylis glomerata L.) leaves to a short term flooding.
Autorzy:
Qiao D; College of Animal Science, Southwest University, Rongchang District, Chongqing, 402460, China.
Zhang Y; College of Animal Science, Southwest University, Rongchang District, Chongqing, 402460, China.
Xiong X; College of Animal Science, Southwest University, Rongchang District, Chongqing, 402460, China.
Li M; College of Animal Science, Southwest University, Rongchang District, Chongqing, 402460, China.
Cai K; College of Animal Science, Southwest University, Rongchang District, Chongqing, 402460, China.
Luo H; College of Animal Science, Southwest University, Rongchang District, Chongqing, 402460, China. .
Zeng B; College of Animal Science, Southwest University, Rongchang District, Chongqing, 402460, China. .
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Źródło:
Hereditas [Hereditas] 2020 May 17; Vol. 157 (1), pp. 20. Date of Electronic Publication: 2020 May 17.
Typ publikacji:
Journal Article
MeSH Terms:
Floods*
Stress, Physiological*
Transcriptome*
Dactylis/*genetics
Dactylis/physiology ; Gene Expression Profiling ; Genes, Plant ; RNA-Seq
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Culturing C2C12 myotubes on micromolded gelatin hydrogels accelerates myotube maturation.
Autorzy:
Denes LT; Department of Molecular Genetics and Microbiology, Center for Neurogenetics, Myology Institute, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.
Riley LA; Department of Physiology and Functional Genomics, Myology Institute, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.
Mijares JR; Department of Physiology and Functional Genomics, Myology Institute, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.
Arboleda JD; Department of Molecular Genetics and Microbiology, Center for Neurogenetics, Myology Institute, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.
McKee K; Department of Molecular Genetics and Microbiology, Center for Neurogenetics, Myology Institute, College of Medicine, University of Florida, Gainesville, FL, 32610, USA.
Esser KA; Department of Physiology and Functional Genomics, Myology Institute, College of Medicine, University of Florida, Gainesville, FL, 32610, USA. .
Wang ET; Department of Molecular Genetics and Microbiology, Center for Neurogenetics, Myology Institute, College of Medicine, University of Florida, Gainesville, FL, 32610, USA. .
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Źródło:
Skeletal muscle [Skelet Muscle] 2019 Jun 07; Vol. 9 (1), pp. 17. Date of Electronic Publication: 2019 Jun 07.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Culture Techniques/*methods
Muscle Fibers, Skeletal/*cytology
Animals ; Cell Differentiation/genetics ; Cell Line ; Gelatin ; Gene Expression Profiling ; Hydrogels ; Mice ; Muscle Development/genetics ; Muscle Fibers, Skeletal/metabolism ; Myoblasts, Skeletal/cytology ; Myoblasts, Skeletal/metabolism ; RNA-Seq ; Surface Properties
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Preclinical rationale for entinostat in embryonal rhabdomyosarcoma.
Autorzy:
Bharathy N; Children's Cancer Therapy Development Institute, 12655 Sw Beaverdam Rd. W, Beaverton, OR, 97005, USA. .
Berlow NE; Children's Cancer Therapy Development Institute, 12655 Sw Beaverdam Rd. W, Beaverton, OR, 97005, USA.
Wang E; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 11724, USA.
Abraham J; Department of Pediatrics, Oregon Health & Science University, Portland, OR, 97239, USA.
Settelmeyer TP; Children's Cancer Therapy Development Institute, 12655 Sw Beaverdam Rd. W, Beaverton, OR, 97005, USA.
Hooper JE; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.
Svalina MN; Children's Cancer Therapy Development Institute, 12655 Sw Beaverdam Rd. W, Beaverton, OR, 97005, USA.
Bajwa Z; Children's Cancer Therapy Development Institute, 12655 Sw Beaverdam Rd. W, Beaverton, OR, 97005, USA.; Department of Pathology, Oregon Health & Science University, Portland, OR, 97239, USA.
Goros MW; Department of Epidemiology and Biostatistics, University of Texas Health Science Center, San Antonio, TX, 78229, USA.
Hernandez BS; Department of Epidemiology and Biostatistics, University of Texas Health Science Center, San Antonio, TX, 78229, USA.
Wolff JE; Department of Pediatric Hematology Oncology and Blood and Marrow Transplantation, Cleveland Clinic Children's, Cleveland, OH, 44195, USA.; Present Address: AbbVie, North Chicago, IL, 60064, USA.
Pal R; Electrical and Computer Engineering, Texas Tech University, Lubbock, TX, 79409, USA.
Davies AM; Champions Oncology, Rockville, MD, 20850, USA.
Ashok A; Champions Oncology, Rockville, MD, 20850, USA.
Bushby D; Champions Oncology, Rockville, MD, 20850, USA.
Mancini M; Champions Oncology, Rockville, MD, 20850, USA.
Noakes C; Champions Oncology, Rockville, MD, 20850, USA.
Goodwin NC; Champions Oncology, Rockville, MD, 20850, USA.
Ordentlich P; Syndax Pharmaceuticals, Waltham, MA, 02451, USA.
Keck J; The Jackson Laboratory, Sacramento, CA, 95838, USA.
Hawkins DS; Seattle Children's Hospital, Seattle, WA, 98105, USA.
Rudzinski ER; Seattle Children's Hospital, Seattle, WA, 98105, USA.
Mansoor A; Department of Pathology, Oregon Health & Science University, Portland, OR, 97239, USA.
Perkins TJ; Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, K1H 8L6, Canada.; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, K1H 8M5, Canada.
Vakoc CR; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 11724, USA.
Michalek JE; Department of Epidemiology and Biostatistics, University of Texas Health Science Center, San Antonio, TX, 78229, USA.
Keller C; Children's Cancer Therapy Development Institute, 12655 Sw Beaverdam Rd. W, Beaverton, OR, 97005, USA. .
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Źródło:
Skeletal muscle [Skelet Muscle] 2019 May 21; Vol. 9 (1), pp. 12. Date of Electronic Publication: 2019 May 21.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Benzamides/*therapeutic use
Histone Deacetylase Inhibitors/*therapeutic use
Pyridines/*therapeutic use
Rhabdomyosarcoma, Embryonal/*drug therapy
Adolescent ; Animals ; Antineoplastic Agents, Phytogenic/administration & dosage ; Antineoplastic Combined Chemotherapy Protocols/administration & dosage ; Benzamides/administration & dosage ; CRISPR-Cas Systems ; Cell Differentiation/drug effects ; Cell Line, Tumor ; Cellular Reprogramming/drug effects ; Cellular Reprogramming/genetics ; Child ; Child, Preschool ; Drug Screening Assays, Antitumor ; Female ; Histone Deacetylase 1/antagonists & inhibitors ; Histone Deacetylase 1/genetics ; Histone Deacetylase Inhibitors/administration & dosage ; Humans ; Male ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Pyridines/administration & dosage ; RNA-Seq ; Rhabdomyosarcoma, Alveolar/drug therapy ; Rhabdomyosarcoma, Alveolar/enzymology ; Rhabdomyosarcoma, Alveolar/pathology ; Rhabdomyosarcoma, Embryonal/enzymology ; Rhabdomyosarcoma, Embryonal/pathology ; Tumor Burden/drug effects ; Tumor Microenvironment/drug effects ; Tumor Microenvironment/genetics ; Vincristine/administration & dosage ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 2571

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