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    Wyświetlanie 1-9 z 9
    Tytuł:
    GQ-130, a novel analogue of thiazolidinedione, improves obesity-induced metabolic alterations in rats: Evidence for the involvement of PPARβ/δ pathway.
    Autorzy:
    Silva OA; Department of Physiology and Pharmacology, Federal University of Pernambuco, Recife, Brazil.
    Ribeiro-Filho HV; National Institute of Biosciences, Brazilian Association for Synchrotron Light Technology, Campinas, São Paulo, Brazil.
    Avelino TM; National Institute of Biosciences, Brazilian Association for Synchrotron Light Technology, Campinas, São Paulo, Brazil.
    Tittanegro TH; National Institute of Biosciences, Brazilian Association for Synchrotron Light Technology, Campinas, São Paulo, Brazil.
    Figueira ACM; National Institute of Biosciences, Brazilian Association for Synchrotron Light Technology, Campinas, São Paulo, Brazil.
    Rabelo LA; Institute of Biological Sciences and Health, Federal University of Alagoas, Maceio, Brazil.
    Pitta IDR; Core of Therapeutic Innovation, Federal University of Pernambuco, Recife, Brazil.
    Lahlou S; Department of Physiology and Pharmacology, School of Medicine, Federal University of Ceará, Fortaleza, Brazil.
    Duarte GP; Department of Physiology and Pharmacology, Federal University of Pernambuco, Recife, Brazil.
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    Źródło:
    Clinical and experimental pharmacology & physiology [Clin Exp Pharmacol Physiol] 2020 May; Vol. 47 (5), pp. 798-808. Date of Electronic Publication: 2020 Jan 24.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Energy Metabolism/*drug effects
    Metabolic Syndrome/*drug therapy
    Obesity/*drug therapy
    PPAR delta/*agonists
    PPAR-beta/*agonists
    Thiazolidinediones/*pharmacology
    Animals ; Biomarkers/blood ; Blood Pressure/drug effects ; Disease Models, Animal ; HEK293 Cells ; Humans ; Insulin Resistance ; Male ; Metabolic Syndrome/etiology ; Metabolic Syndrome/metabolism ; Metabolic Syndrome/physiopathology ; Obesity/complications ; Obesity/metabolism ; Obesity/physiopathology ; PPAR delta/genetics ; PPAR delta/metabolism ; PPAR-beta/genetics ; PPAR-beta/metabolism ; Rats, Wistar ; Signal Transduction ; Time Factors
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Antioxidant, antihyperglycemic, and antidiabetic activity of Apis mellifera bee tea.
    Autorzy:
    Melo da Cunha JDS; Binational Campus Oiapoque, Federal University of Amapá-UNIFAP, Amapá, Brazil.; Research Group on Biotechnology and Bioprospecting Applied to Metabolism, Federal University of Grande Dourados-UFGD, Dourados, Brazil.
    Alfredo TM; Research Group on Biotechnology and Bioprospecting Applied to Metabolism, Federal University of Grande Dourados-UFGD, Dourados, Brazil.
    Dos Santos JM; Research Group on Biotechnology and Bioprospecting Applied to Metabolism, Federal University of Grande Dourados-UFGD, Dourados, Brazil.
    Alves Junior VV; School of Environmental and Biological Science, Federal University of Grande Dourados-UFGD, Dourados, Brazil.
    Rabelo LA; Laboratory of Cardiovascular Reactivity-LRC, Nucleus of Metabolic Syndrome, Biological Sciences and Health Institute-ICBS, Federal University of Alagoas-UFAL, Alagoas, Brazil.
    Lima ES; Faculty of Pharmaceutical Sciences, Federal University of Amazonas, Manaus, Brazil.
    Boleti APA; Research Group on Biotechnology and Bioprospecting Applied to Metabolism, Federal University of Grande Dourados-UFGD, Dourados, Brazil.
    Carollo CA; Laboratory of Natural Products am Mass Spectrometry, Federal University of Mato Grosso do Sul-UFMS, Mato Grosso do Sul, Brazil.
    Dos Santos EL; Research Group on Biotechnology and Bioprospecting Applied to Metabolism, Federal University of Grande Dourados-UFGD, Dourados, Brazil.; School of Environmental and Biological Science, Federal University of Grande Dourados-UFGD, Dourados, Brazil.
    de Picoli Souza K; Research Group on Biotechnology and Bioprospecting Applied to Metabolism, Federal University of Grande Dourados-UFGD, Dourados, Brazil.; School of Environmental and Biological Science, Federal University of Grande Dourados-UFGD, Dourados, Brazil.
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    Źródło:
    PloS one [PLoS One] 2018 Jun 05; Vol. 13 (6), pp. e0197071. Date of Electronic Publication: 2018 Jun 05 (Print Publication: 2018).
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Antioxidants*/chemistry
    Antioxidants*/pharmacology
    Hypoglycemic Agents*/chemistry
    Hypoglycemic Agents*/pharmacology
    Bees/*chemistry
    Diabetes Mellitus, Experimental/*drug therapy
    Tea/*chemistry
    Adult ; Animals ; Brazil ; Diabetes Mellitus, Experimental/metabolism ; Diabetes Mellitus, Experimental/pathology ; Female ; Humans ; Male ; Mice
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Genetic Deletion of ACE2 Induces Vascular Dysfunction in C57BL/6 Mice: Role of Nitric Oxide Imbalance and Oxidative Stress.
    Autorzy:
    Rabelo LA; Max-Delbrück-Center for Molecular Medicine, Berlin, Germany.; Laboratório de Reatividade Cardiovascular, Universidade Federal de Alagoas, Maceió, Alagoas, Brazil.; Instituto Nacional de Ciência e Tecnologia em NanoBiofarmacêutica (NanoBIOFAR).
    Todiras M; Max-Delbrück-Center for Molecular Medicine, Berlin, Germany.; Instituto Nacional de Ciência e Tecnologia em NanoBiofarmacêutica (NanoBIOFAR).
    Nunes-Souza V; Max-Delbrück-Center for Molecular Medicine, Berlin, Germany.; Laboratório de Reatividade Cardiovascular, Universidade Federal de Alagoas, Maceió, Alagoas, Brazil.; Instituto Nacional de Ciência e Tecnologia em NanoBiofarmacêutica (NanoBIOFAR).
    Qadri F; Max-Delbrück-Center for Molecular Medicine, Berlin, Germany.; Charité University Medicine, Berlin, Germany.
    Szijártó IA; Nephrology/Intensive Care, Charité Campus Virchow Klinikum, Experimental and Clinical Research Center (ECRC), Berlin, Germany.
    Gollasch M; Nephrology/Intensive Care, Charité Campus Virchow Klinikum, Experimental and Clinical Research Center (ECRC), Berlin, Germany.
    Penninger JM; Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna, Austria.
    Bader M; Max-Delbrück-Center for Molecular Medicine, Berlin, Germany.; Instituto Nacional de Ciência e Tecnologia em NanoBiofarmacêutica (NanoBIOFAR).; Charité University Medicine, Berlin, Germany.; Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
    Santos RA; Instituto Nacional de Ciência e Tecnologia em NanoBiofarmacêutica (NanoBIOFAR).; Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
    Alenina N; Max-Delbrück-Center for Molecular Medicine, Berlin, Germany.; Instituto Nacional de Ciência e Tecnologia em NanoBiofarmacêutica (NanoBIOFAR).; Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
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    Źródło:
    PloS one [PLoS One] 2016 Apr 12; Vol. 11 (4), pp. e0150255. Date of Electronic Publication: 2016 Apr 12 (Print Publication: 2016).
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Aorta/*metabolism
    Nitric Oxide/*metabolism
    Oxidative Stress/*genetics
    Peptidyl-Dipeptidase A/*genetics
    Angiotensin-Converting Enzyme 2 ; Animals ; Antioxidants/metabolism ; Endothelium, Vascular/metabolism ; Female ; Gene Deletion ; Lipid Peroxidation/genetics ; Male ; Mice ; Mice, Inbred C57BL ; Nitric Oxide Synthase Type III/genetics ; Oxidation-Reduction ; RNA, Messenger/genetics ; Renin-Angiotensin System/genetics ; Superoxide Dismutase/genetics ; Vasodilation/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Antioxidant and cytotoxic activity of hydroethanolic extract from Jacaranda decurrens leaves.
    Autorzy:
    Casagrande JC; Federal University of Grande Dourados, Dourados, Mato Grosso do Sul, Brazil.
    Macorini LF; Federal University of Grande Dourados, Dourados, Mato Grosso do Sul, Brazil.
    Antunes KA; Federal University of Grande Dourados, Dourados, Mato Grosso do Sul, Brazil.
    Santos UP; Federal University of Grande Dourados, Dourados, Mato Grosso do Sul, Brazil.
    Campos JF; Federal University of Grande Dourados, Dourados, Mato Grosso do Sul, Brazil.
    Dias-Júnior NM; Federal University of Alagoas, Maceió, Alagoas, Brazil.
    Sangalli A; Federal University of Grande Dourados, Dourados, Mato Grosso do Sul, Brazil.
    Lima Cardoso CA; State University of Mato Grosso do Sul, Dourados, Mato Grosso do Sul, Brazil.
    do Carmo Vieira M; Federal University of Grande Dourados, Dourados, Mato Grosso do Sul, Brazil.
    Rabelo LA; Federal University of Alagoas, Maceió, Alagoas, Brazil.
    Paredes-Gamero EJ; Federal University of São Paulo, São Paulo, São Paulo, Brazil.
    Dos Santos EL; Federal University of Grande Dourados, Dourados, Mato Grosso do Sul, Brazil.
    de Picoli Souza K; Federal University of Grande Dourados, Dourados, Mato Grosso do Sul, Brazil.
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    Źródło:
    PloS one [PLoS One] 2014 Nov 17; Vol. 9 (11), pp. e112748. Date of Electronic Publication: 2014 Nov 17 (Print Publication: 2014).
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Antioxidants/*pharmacology
    Plant Extracts/*pharmacology
    Plant Leaves/*chemistry
    Plants, Medicinal/*chemistry
    Antioxidants/chemistry ; Antioxidants/toxicity ; Biphenyl Compounds/antagonists & inhibitors ; Cell Survival/drug effects ; Flavonoids/chemistry ; Flavonoids/pharmacology ; Hemolysis/drug effects ; Humans ; Inhibitory Concentration 50 ; K562 Cells ; Lipid Peroxidation/drug effects ; Oxidation-Reduction/drug effects ; Phenols/chemistry ; Phenols/pharmacology ; Picrates/antagonists & inhibitors ; Plant Extracts/chemistry ; Plant Extracts/toxicity
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Oxidative stress as an underlying contributor in the development of chronic complications in diabetes mellitus.
    Autorzy:
    de M Bandeira S; Medical Course of Cariri, Federal University of Ceará, Barbalha, Ceará 63180-970, Brazil. .
    da Fonseca LJ
    da S Guedes G
    Rabelo LA
    Goulart MO
    Vasconcelos SM
    Pokaż więcej
    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2013 Feb 05; Vol. 14 (2), pp. 3265-84. Date of Electronic Publication: 2013 Feb 05.
    Typ publikacji:
    Journal Article
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-9 z 9

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