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Wyszukujesz frazę ""Racemases and Epimerases"" wg kryterium: Temat


Tytuł :
Human serine racemase is inhibited by glyceraldehyde 3-phosphate, but not by glyceraldehyde 3-phosphate dehydrogenase.
Autorzy :
Michielon A; Dipartimento di Scienze degli Alimenti e del Farmaco, Università degli Studi di Parma, Parco Area delle Scienze 27/A, 43124 Parma, Italy.
Marchesani F; Dipartimento di Scienze degli Alimenti e del Farmaco, Università degli Studi di Parma, Parco Area delle Scienze 27/A, 43124 Parma, Italy.
Faggiano S; Dipartimento di Scienze degli Alimenti e del Farmaco, Università degli Studi di Parma, Parco Area delle Scienze 27/A, 43124 Parma, Italy; Istituto di Biofisica, CNR, Via G. Moruzzi 1, 56124 Pisa, Italy.
Giaccari R; Dipartimento di Scienze degli Alimenti e del Farmaco, Università degli Studi di Parma, Parco Area delle Scienze 27/A, 43124 Parma, Italy.
Campanini B; Dipartimento di Scienze degli Alimenti e del Farmaco, Università degli Studi di Parma, Parco Area delle Scienze 27/A, 43124 Parma, Italy.
Bettati S; Dipartimento di Medicina e Chirurgia, Via Volturno 39, 43125 Parma, Italy.
Mozzarelli A; Dipartimento di Scienze degli Alimenti e del Farmaco, Università degli Studi di Parma, Parco Area delle Scienze 27/A, 43124 Parma, Italy; Istituto di Biofisica, CNR, Via G. Moruzzi 1, 56124 Pisa, Italy.
Bruno S; Dipartimento di Scienze degli Alimenti e del Farmaco, Università degli Studi di Parma, Parco Area delle Scienze 27/A, 43124 Parma, Italy. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Proteins and proteomics [Biochim Biophys Acta Proteins Proteom] 2021 Jan; Vol. 1869 (1), pp. 140544. Date of Electronic Publication: 2020 Sep 22.
Typ publikacji :
Journal Article
MeSH Terms :
Adenosine Triphosphate/*chemistry
Enzyme Inhibitors/*chemistry
Glyceraldehyde 3-Phosphate/*chemistry
Glyceraldehyde-3-Phosphate Dehydrogenases/*chemistry
Pyridoxal Phosphate/*chemistry
Racemases and Epimerases/*chemistry
2,3-Diphosphoglycerate/chemistry ; 2,3-Diphosphoglycerate/metabolism ; Adenosine Triphosphate/metabolism ; Aldehydes/chemistry ; Aldehydes/metabolism ; Catalytic Domain ; Cloning, Molecular ; Enzyme Inhibitors/metabolism ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Gene Expression ; Genetic Vectors/chemistry ; Genetic Vectors/metabolism ; Glyceraldehyde/chemistry ; Glyceraldehyde/metabolism ; Glyceraldehyde 3-Phosphate/metabolism ; Glyceraldehyde-3-Phosphate Dehydrogenases/genetics ; Glyceraldehyde-3-Phosphate Dehydrogenases/metabolism ; Humans ; Kinetics ; Models, Molecular ; Protein Binding ; Pyridoxal Phosphate/metabolism ; Racemases and Epimerases/antagonists & inhibitors ; Racemases and Epimerases/genetics ; Racemases and Epimerases/metabolism ; Recombinant Proteins/chemistry ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Stereoisomerism ; Substrate Specificity
Czasopismo naukowe
Tytuł :
Serine Racemase Deletion Affects the Excitatory/Inhibitory Balance of the Hippocampal CA1 Network.
Autorzy :
Ploux E; UNICAEN, INSERM, COMETE, Cyceron, CHU Caen, Normandie University, 14000 Caen, France.
Bouet V; UNICAEN, INSERM, COMETE, Cyceron, CHU Caen, Normandie University, 14000 Caen, France.
Radzishevsky I; Department of Biochemistry, Technion-Israel Institute of Technology, Rappaport Faculty of Medicine, Haifa 31096, Israel.
Wolosker H; Department of Biochemistry, Technion-Israel Institute of Technology, Rappaport Faculty of Medicine, Haifa 31096, Israel.
Freret T; UNICAEN, INSERM, COMETE, Cyceron, CHU Caen, Normandie University, 14000 Caen, France.
Billard JM; UNICAEN, INSERM, COMETE, Cyceron, CHU Caen, Normandie University, 14000 Caen, France.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Dec 11; Vol. 21 (24). Date of Electronic Publication: 2020 Dec 11.
Typ publikacji :
Journal Article
MeSH Terms :
CA1 Region, Hippocampal/*metabolism
Racemases and Epimerases/*metabolism
Amino Acids/metabolism ; Animals ; Electrophysiology ; Hippocampus/metabolism ; Long-Term Potentiation/physiology ; Male ; Memory/physiology ; Mice ; Morris Water Maze Test ; Neuronal Plasticity/physiology ; Racemases and Epimerases/genetics ; Receptors, N-Methyl-D-Aspartate/metabolism
Czasopismo naukowe
Tytuł :
Postsynaptic Serine Racemase Regulates NMDA Receptor Function.
Autorzy :
Wong JM; Center for Neuroscience, University of California Davis, Davis, California 95616.; Neuroscience Graduate Group, University of California Davis, Davis, California 95616.
Folorunso OO; Department of Psychiatry, Harvard Medical School, Boston, Massachusetts 02115.; Translational Psychiatry Laboratory, McLean Hospital, Belmont, Massachusetts 02478.
Barragan EV; Center for Neuroscience, University of California Davis, Davis, California 95616.; Neuroscience Graduate Group, University of California Davis, Davis, California 95616.
Berciu C; Department of Psychiatry, Harvard Medical School, Boston, Massachusetts 02115.
Harvey TL; Translational Psychiatry Laboratory, McLean Hospital, Belmont, Massachusetts 02478.
Coyle JT; Department of Psychiatry, Harvard Medical School, Boston, Massachusetts 02115.
Balu DT; Department of Psychiatry, Harvard Medical School, Boston, Massachusetts 02115 .; Translational Psychiatry Laboratory, McLean Hospital, Belmont, Massachusetts 02478.
Gray JA; Center for Neuroscience, University of California Davis, Davis, California 95616 .; Department of Neurology, University ofCalifornia Davis, Davis, California 95616.
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Źródło :
The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2020 Dec 09; Vol. 40 (50), pp. 9564-9575. Date of Electronic Publication: 2020 Nov 06.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Dendrites/*metabolism
Pyramidal Cells/*metabolism
Racemases and Epimerases/*metabolism
Receptors, N-Methyl-D-Aspartate/*metabolism
Synapses/*metabolism
Age Factors ; Animals ; CA1 Region, Hippocampal/metabolism ; Female ; Male ; Mice ; Mice, Knockout ; Neuronal Plasticity/physiology ; Racemases and Epimerases/genetics ; Synaptic Transmission/physiology
Czasopismo naukowe
Tytuł :
Sp4 controls constitutive expression of neuronal serine racemase and NF-E2-related factor-2 mediates its induction by valproic acid.
Autorzy :
Zhang H; School of Optometry and Ophthalmology and the Eye Hospital, Wenzhou Medical University, China; State Key Laboratory of Optometry, Ophthalmology, and Visual Science, 270 Xueyuan Road, Wenzhou, Zhejiang 325003, China.
Lu J; School of Optometry and Ophthalmology and the Eye Hospital, Wenzhou Medical University, China; School of Laboratory Medicine and Life Science, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
Wu S; School of Optometry and Ophthalmology and the Eye Hospital, Wenzhou Medical University, China; State Key Laboratory of Optometry, Ophthalmology, and Visual Science, 270 Xueyuan Road, Wenzhou, Zhejiang 325003, China. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Gene regulatory mechanisms [Biochim Biophys Acta Gene Regul Mech] 2020 Sep; Vol. 1863 (9), pp. 194597. Date of Electronic Publication: 2020 Jun 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation/*drug effects
NF-E2-Related Factor 2/*metabolism
Neurons/*drug effects
Neurons/*metabolism
Racemases and Epimerases/*genetics
Sp4 Transcription Factor/*metabolism
Valproic Acid/*pharmacology
Animals ; Base Sequence ; Cell Line ; Fluorescent Antibody Technique ; Genes, Reporter ; Histone Deacetylases/metabolism ; Humans ; Mice ; Mutation ; Promoter Regions, Genetic ; RNA, Messenger/genetics ; Racemases and Epimerases/chemistry ; Racemases and Epimerases/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
Mechanism of eukaryotic serine racemase-catalyzed serine dehydration.
Autorzy :
Ito T; Department of Applied Molecular Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University, Furou-chou, Chikusa, Nagoya, Aichi 464-8601, Japan.
Matsuoka M; Department of Applied Molecular Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University, Furou-chou, Chikusa, Nagoya, Aichi 464-8601, Japan.
Goto M; Department of Biomolecular Science, Faculty of Science, Toho University, Miyama 2-2-1, Funabashi, Chiba 274-8510, Japan. Electronic address: .
Watanabe S; Department of Biomolecular Science, Faculty of Science, Toho University, Miyama 2-2-1, Funabashi, Chiba 274-8510, Japan.
Mizobuchi T; Department of Biomolecular Science, Faculty of Science, Toho University, Miyama 2-2-1, Funabashi, Chiba 274-8510, Japan.
Matsushita K; Department of Biomolecular Science, Faculty of Science, Toho University, Miyama 2-2-1, Funabashi, Chiba 274-8510, Japan.
Nasu R; Department of Applied Molecular Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University, Furou-chou, Chikusa, Nagoya, Aichi 464-8601, Japan.
Hemmi H; Department of Applied Molecular Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University, Furou-chou, Chikusa, Nagoya, Aichi 464-8601, Japan.
Yoshimura T; Department of Applied Molecular Biosciences, Graduate School of Bioagricultural Sciences, Nagoya University, Furou-chou, Chikusa, Nagoya, Aichi 464-8601, Japan. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Proteins and proteomics [Biochim Biophys Acta Proteins Proteom] 2020 Sep; Vol. 1868 (9), pp. 140460. Date of Electronic Publication: 2020 May 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Dehydration*
Eukaryota/*enzymology
Racemases and Epimerases/*chemistry
Racemases and Epimerases/*metabolism
Serine/*metabolism
Animals ; Catalysis ; Crystallization ; Dictyostelium/enzymology ; Kinetics ; Mice ; Models, Molecular ; Racemases and Epimerases/genetics ; Receptors, N-Methyl-D-Aspartate ; Substrate Specificity
Czasopismo naukowe
Tytuł :
Determinants of the Nucleotide Specificity in the Carbohydrate Epimerase Family 1.
Autorzy :
Van Overtveldt S; Centre for Synthetic Biology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, Gent, 9000, Belgium.
Da Costa M; Centre for Synthetic Biology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, Gent, 9000, Belgium.
Gevaert O; Centre for Synthetic Biology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, Gent, 9000, Belgium.
Joosten HJ; Bio-Prodict BV, Nieuwe Marktstraat 54E, Nijmegen, 6511 AA, The Netherlands.
Beerens K; Centre for Synthetic Biology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, Gent, 9000, Belgium.
Desmet T; Centre for Synthetic Biology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, Gent, 9000, Belgium.
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Źródło :
Biotechnology journal [Biotechnol J] 2020 Nov; Vol. 15 (11), pp. e2000132. Date of Electronic Publication: 2020 Sep 06.
Typ publikacji :
Journal Article
MeSH Terms :
Nucleotides*
Racemases and Epimerases*
Carbohydrate Epimerases/genetics ; Carbohydrate Epimerases/metabolism ; Carbohydrate Metabolism
Czasopismo naukowe
Tytuł :
β-Strand-mediated interactions of protein domains.
Autorzy :
Bhat AS; Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Kinch LN; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Grishin NV; Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, Texas, USA.; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
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Źródło :
Proteins [Proteins] 2020 Nov; Vol. 88 (11), pp. 1513-1527. Date of Electronic Publication: 2020 Jul 11.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Interaction Domains and Motifs*
Amino Acid Isomerases/*chemistry
Penicillin-Binding Proteins/*chemistry
Racemases and Epimerases/*chemistry
Amino Acid Isomerases/metabolism ; Amino Acid Sequence ; Animals ; Bacteria/chemistry ; Binding Sites ; Databases, Protein ; Datasets as Topic ; Humans ; Models, Molecular ; Penicillin-Binding Proteins/metabolism ; Protein Binding ; Protein Conformation, alpha-Helical ; Protein Conformation, beta-Strand ; Racemases and Epimerases/metabolism ; Thermodynamics
Czasopismo naukowe
Tytuł :
Uncovering a superfamily of nickel-dependent hydroxyacid racemases and epimerases.
Autorzy :
Desguin B; Louvain Institute of Biomolecular Science and Technology, UCLouvain, 1348, Louvain-La-Neuve, Belgium. .
Urdiain-Arraiza J; Louvain Institute of Biomolecular Science and Technology, UCLouvain, 1348, Louvain-La-Neuve, Belgium.
Da Costa M; Department of Biotechnology, Ghent University, 9000, Ghent, Belgium.
Fellner M; Biochemistry, University of Otago, PO Box 56, Dunedin, Otago, 9054, New Zealand.; Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI, 48824, USA.
Hu J; Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI, 48824, USA.; Department of Chemistry, Michigan State University, East Lansing, MI, 48824, USA.
Hausinger RP; Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI, 48824, USA.; Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, MI, 48824, USA.
Desmet T; Department of Biotechnology, Ghent University, 9000, Ghent, Belgium.
Hols P; Louvain Institute of Biomolecular Science and Technology, UCLouvain, 1348, Louvain-La-Neuve, Belgium.
Soumillion P; Louvain Institute of Biomolecular Science and Technology, UCLouvain, 1348, Louvain-La-Neuve, Belgium.
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Źródło :
Scientific reports [Sci Rep] 2020 Oct 22; Vol. 10 (1), pp. 18123. Date of Electronic Publication: 2020 Oct 22.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Bacteria/*enzymology
Bacterial Proteins/*metabolism
Hydroxy Acids/*chemistry
Nickel/*metabolism
Nucleotides/*metabolism
Racemases and Epimerases/*metabolism
Bacterial Proteins/chemistry ; Crystallography, X-Ray ; Models, Molecular ; Nickel/chemistry ; Nucleotides/chemistry ; Protein Conformation ; Racemases and Epimerases/chemistry
Czasopismo naukowe
Tytuł :
TGFβ1-Smad3 signaling mediates the formation of a stable serine racemase dimer in microglia.
Autorzy :
Beltrán-Castillo S; Departamento de Neurología, Facultad de Medicina, Universidad Católica de Chile, Av. Libertador Bernardo O'Higgins 340, Santiago, Chile. Electronic address: .
Triviño JJ; Departamento de Neurología, Facultad de Medicina, Universidad Católica de Chile, Av. Libertador Bernardo O'Higgins 340, Santiago, Chile. Electronic address: .
Eugenín J; Departamento de Biología, Facultad de Química y Biología, Universidad de Santiago de Chile, Av. Libertador Bernardo O'Higgins 3363, Estación central, Santiago, Chile.. Electronic address: .
von Bernhardi R; Departamento de Neurología, Facultad de Medicina, Universidad Católica de Chile, Av. Libertador Bernardo O'Higgins 340, Santiago, Chile. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Proteins and proteomics [Biochim Biophys Acta Proteins Proteom] 2020 Sep; Vol. 1868 (9), pp. 140447. Date of Electronic Publication: 2020 May 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Microglia/*metabolism
Racemases and Epimerases/*metabolism
Signal Transduction/*physiology
Smad3 Protein/*metabolism
Transforming Growth Factor beta1/*metabolism
Animals ; Astrocytes/metabolism ; Cell Culture Techniques ; Cell Line ; Crystallography, X-Ray ; Cytokines/metabolism ; Interleukin-1beta/metabolism ; Lipopolysaccharides/adverse effects ; Mice ; Mice, Inbred C57BL ; Microglia/drug effects ; Racemases and Epimerases/chemistry ; Signal Transduction/drug effects ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł :
Potent Inhibition of Mandelate Racemase by Boronic Acids: Boron as a Mimic of a Carbon Acid Center.
Autorzy :
Sharma AN; Department of Biochemistry and Molecular Biology, Dalhousie University, Halifax, NS B3H 4R2, Canada.
Grandinetti L; Department of Biological Sciences, Marquette University, Milwaukee, Wisconsin 53201-1881, United States.
Johnson ER; Department of Chemistry, Dalhousie University, Halifax, NS B3H 4R2, Canada.
St Maurice M; Department of Biological Sciences, Marquette University, Milwaukee, Wisconsin 53201-1881, United States.
Bearne SL; Department of Biochemistry and Molecular Biology, Dalhousie University, Halifax, NS B3H 4R2, Canada.; Department of Chemistry, Dalhousie University, Halifax, NS B3H 4R2, Canada.
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Źródło :
Biochemistry [Biochemistry] 2020 Aug 25; Vol. 59 (33), pp. 3026-3037. Date of Electronic Publication: 2020 Aug 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Boron/*pharmacology
Boronic Acids/*pharmacology
Racemases and Epimerases/*antagonists & inhibitors
Amino Acid Substitution ; Binding Sites/drug effects ; Boron/chemistry ; Boronic Acids/pharmacokinetics ; Carbon/chemistry ; Carbon/pharmacokinetics ; Carbon/pharmacology ; Carbonic Acid/chemistry ; Carbonic Acid/pharmacology ; Catalysis/drug effects ; Catalytic Domain/drug effects ; Kinetics ; Magnetic Resonance Spectroscopy ; Models, Molecular ; Mutagenesis, Site-Directed ; Racemases and Epimerases/genetics ; Racemases and Epimerases/metabolism ; Stereoisomerism ; Structure-Activity Relationship ; Substrate Specificity
Czasopismo naukowe
Tytuł :
Through the Looking Glass: Chiral Recognition of Substrates and Products at the Active Sites of Racemases and Epimerases.
Autorzy :
Bearne SL; Department of Biochemistry & Molecular Biology, Department of Chemistry, Dalhousie University, Halifax, Nova Scotia, B3H 4R2, Canada.
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Źródło :
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2020 Aug 17; Vol. 26 (46), pp. 10367-10390. Date of Electronic Publication: 2020 Jul 21.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Racemases and Epimerases*/chemistry
Binding Sites ; Catalysis ; Catalytic Domain ; Stereoisomerism
Czasopismo naukowe
Tytuł :
Bacterial production of maize and human serine racemases as partially active inclusion bodies for d-serine synthesis.
Autorzy :
Wang R; Anhui Agricultural University 130, West Road Changjiang, Hefei, 230036, China.
Li J; Anhui Agricultural University 130, West Road Changjiang, Hefei, 230036, China.
Dang D; Anhui Agricultural University 130, West Road Changjiang, Hefei, 230036, China.
Hu J; Anhui Agricultural University 130, West Road Changjiang, Hefei, 230036, China.
Hu Y; Anhui Agricultural University 130, West Road Changjiang, Hefei, 230036, China.
Fan J; Anhui Agricultural University 130, West Road Changjiang, Hefei, 230036, China. Electronic address: .
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Źródło :
Enzyme and microbial technology [Enzyme Microb Technol] 2020 Jun; Vol. 137, pp. 109547. Date of Electronic Publication: 2020 Mar 04.
Typ publikacji :
Journal Article
MeSH Terms :
Escherichia coli/*metabolism
Inclusion Bodies/*metabolism
Racemases and Epimerases/*biosynthesis
Serine/*biosynthesis
Zea mays/*enzymology
Escherichia coli/genetics ; Humans ; Protein Binding ; Racemases and Epimerases/genetics ; Recombinant Proteins/biosynthesis ; Spectroscopy, Fourier Transform Infrared
Czasopismo naukowe
Tytuł :
Accelerated identification of serine racemase inhibitor from Centella asiatica.
Autorzy :
Rani K; Department of Biophysics, All India Institute of Medical Sciences, New Delhi, India.
Tyagi M; Department of Biophysics, All India Institute of Medical Sciences, New Delhi, India.
Mazumder M; School of Life Sciences, Jawaharlal Nehru University, New Delhi, India.
Singh A; Sciex, Gurgaon, India.
Shanmugam A; Centre of Advanced Study in Marine Biology, Faculty of Marine Sciences, Annamalai University, Parangipettai, India.
Dalal K; All India Institute of Ayurveda, New Delhi, India.
Pillai M; Sciex, Gurgaon, India.
Samudrala G; School of Life Sciences, Jawaharlal Nehru University, New Delhi, India.
Kumar S; Department of Biophysics, All India Institute of Medical Sciences, New Delhi, India.
Srinivasan A; Department of Biophysics, All India Institute of Medical Sciences, New Delhi, India. .; Department of Biochemistry, Jamia Hamdard, Hamdard Nagar, New Delhi, India. .
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Źródło :
Scientific reports [Sci Rep] 2020 Mar 13; Vol. 10 (1), pp. 4640. Date of Electronic Publication: 2020 Mar 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Centella/*chemistry
Enzyme Inhibitors/*isolation & purification
Racemases and Epimerases/*antagonists & inhibitors
Triterpenes/*isolation & purification
Binding Sites ; Enzyme Inhibitors/chemistry ; Enzyme Inhibitors/pharmacology ; Humans ; Mass Spectrometry ; Models, Molecular ; Molecular Docking Simulation ; Plant Extracts/chemistry ; Plant Extracts/isolation & purification ; Plant Extracts/pharmacology ; Protein Binding ; Racemases and Epimerases/chemistry ; Spectroscopy, Fourier Transform Infrared ; Triterpenes/chemistry ; Triterpenes/pharmacology
Czasopismo naukowe
Tytuł :
Catalytic mechanism and properties of pyridoxal 5'-phosphate independent racemases: how enzymes alter mismatched acidity and basicity.
Autorzy :
Fischer C; Department of Chemistry, University of Alberta, 11227 Saskatchewan Drive, Edmonton, Alberta, Canada T6G 2G2. .
Ahn YC
Vederas JC
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Źródło :
Natural product reports [Nat Prod Rep] 2019 Dec 11; Vol. 36 (12), pp. 1687-1705.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Enzyme Inhibitors/*pharmacology
Pyridoxal Phosphate/*metabolism
Racemases and Epimerases/*chemistry
Racemases and Epimerases/*metabolism
Amino Acid Isomerases/antagonists & inhibitors ; Amino Acid Isomerases/chemistry ; Amino Acid Isomerases/metabolism ; Enzyme Inhibitors/chemistry ; Protein Conformation ; Racemases and Epimerases/antagonists & inhibitors ; Sulfhydryl Compounds/metabolism
Czasopismo naukowe
Tytuł :
d-serine in physiological and pathological brain aging.
Autorzy :
Ploux E; Normandie Univ, UNICAEN, INSERM, CYCERON, COMETE, 14000 Caen, France. Electronic address: .
Freret T; Normandie Univ, UNICAEN, INSERM, CYCERON, COMETE, 14000 Caen, France.
Billard JM; Normandie Univ, UNICAEN, INSERM, CYCERON, COMETE, 14000 Caen, France. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Proteins and proteomics [Biochim Biophys Acta Proteins Proteom] 2021 Jan; Vol. 1869 (1), pp. 140542. Date of Electronic Publication: 2020 Sep 18.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Aging/*metabolism
Alzheimer Disease/*metabolism
Neuronal Plasticity/*physiology
Receptors, N-Methyl-D-Aspartate/*metabolism
Serine/*metabolism
Aging/pathology ; Alzheimer Disease/genetics ; Alzheimer Disease/pathology ; Animals ; Astrocytes/metabolism ; Astrocytes/pathology ; Cognition/physiology ; Gene Expression ; Glucose/metabolism ; Glutamic Acid/metabolism ; Hippocampus/metabolism ; Hippocampus/pathology ; Humans ; Memory/physiology ; Neurons/metabolism ; Neurons/pathology ; Racemases and Epimerases/genetics ; Racemases and Epimerases/metabolism ; Receptors, N-Methyl-D-Aspartate/genetics
Czasopismo naukowe
Tytuł :
Epimers of Vitamin D: A Review.
Autorzy :
Al-Zohily B; Department of Chemistry, College of Science, United Arab Emirates University, Al Ain 15551, UAE.
Al-Menhali A; Department of Biology, College of Science, United Arab Emirates University, Al Ain 15551, UAE.
Gariballa S; Internal Medicine, Faculty of Medicine & Health Sciences, United Arab Emirates University, Al Ain 15551, UAE.
Haq A; Department of Food Technology, School of Interdisciplinary Sciences and Technology, Jamia Hamdard University, New Delhi-110062, India.
Shah I; Department of Chemistry, College of Science, United Arab Emirates University, Al Ain 15551, UAE.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Jan 11; Vol. 21 (2). Date of Electronic Publication: 2020 Jan 11.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Racemases and Epimerases/*metabolism
Vitamin D/*metabolism
Vitamin D Deficiency/*metabolism
Animals ; Humans ; Isomerism ; Racemases and Epimerases/genetics ; Vitamin D/analogs & derivatives ; Vitamin D/chemistry ; Vitamin D Deficiency/genetics
Czasopismo naukowe
Tytuł :
Distribution and evolution of the serine/aspartate racemase family in plants.
Autorzy :
Uda K; Laboratory of Biochemistry, Faculty of Science and Technology, Kochi University, Kochi, 780-8520, Japan. Electronic address: .
Edashige Y; Laboratory of Biochemistry, Faculty of Science and Technology, Kochi University, Kochi, 780-8520, Japan.
Nishimura R; Laboratory of Biochemistry, Faculty of Science and Technology, Kochi University, Kochi, 780-8520, Japan.
Shikano Y; Laboratory of Biochemistry, Faculty of Science and Technology, Kochi University, Kochi, 780-8520, Japan.
Matsui T; Laboratory of Plant Taxonomy, Faculty of Science and Technology, Kochi University, Kochi, 780-8520, Japan.
Radkov AD; Department of Biochemistry and Biophysics, University of California, San Francisco, CA, 94158, USA.
Moe LA; Department of Plant and Soil Sciences, 311 Plant Science Building, University of Kentucky, Lexington, KY, 40546-0312, USA.
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Źródło :
Phytochemistry [Phytochemistry] 2020 Jan; Vol. 169, pp. 112164. Date of Electronic Publication: 2019 Oct 14.
Typ publikacji :
Journal Article
MeSH Terms :
Amino Acid Isomerases/*metabolism
Racemases and Epimerases/*metabolism
Amino Acid Isomerases/genetics ; Biocatalysis ; Gene Expression Regulation, Enzymologic/genetics ; Lycopersicon esculentum/enzymology ; Manihot/enzymology ; Medicago truncatula/enzymology ; Phylogeny ; Racemases and Epimerases/genetics ; Sphagnopsida/enzymology ; Spirogyra/enzymology
Czasopismo naukowe
Tytuł :
Serine racemase enhances growth of colorectal cancer by producing pyruvate from serine.
Autorzy :
Ohshima K; Department of Pathology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Nojima S; Department of Pathology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Tahara S; Department of Pathology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Kurashige M; Department of Pathology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Kawasaki K; Department of Pathology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Hori Y; Department of Pathology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Taniguchi M; Department of Biotechnology, Osaka University Graduate School of Engineering, Suita, Osaka, Japan.
Umakoshi Y; Department of Biotechnology, Osaka University Graduate School of Engineering, Suita, Osaka, Japan.
Okuzaki D; Genome Information Research Center, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan.; Single Cell Genomics, Human Immunology, WPI Immunology Frontier Research Center, Osaka University, Osaka, Japan.; Institute for Open and Transdisciplinary Research Initiatives, Osaka University, Osaka, Japan.
Wada N; Department of Pathology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.; Department of Diagnostic Pathology, Osaka City University, Osaka, Osaka, Japan.
Ikeda JI; Department of Diagnostic Pathology, Chiba University Graduate School of Medicine, Chiba, Chiba, Japan.
Fukusaki E; Department of Biotechnology, Osaka University Graduate School of Engineering, Suita, Osaka, Japan.
Morii E; Department of Pathology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan. .
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Źródło :
Nature metabolism [Nat Metab] 2020 Jan; Vol. 2 (1), pp. 81-96. Date of Electronic Publication: 2020 Jan 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Proliferation*
Colorectal Neoplasms/*pathology
Pyruvic Acid/*metabolism
Racemases and Epimerases/*metabolism
Serine/*metabolism
Animals ; Cell Line, Tumor ; Colorectal Neoplasms/metabolism ; Heterografts ; Humans ; Mice ; Mice, Nude ; RNA, Messenger/genetics ; Racemases and Epimerases/genetics ; Up-Regulation
Czasopismo naukowe
Tytuł :
Fusion and secretory expression of an exo-inulinase and a d-allulose 3-epimerase to produce d-allulose syrup from inulin.
Autorzy :
Huang Y; College of Food Science and Light Industry, Nanjing Tech University, Nanjing, China.; State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing Tech University, Nanjing, China.
Li L; College of Food Science and Light Industry, Nanjing Tech University, Nanjing, China.; State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing Tech University, Nanjing, China.
Chi Y; College of Food Science and Light Industry, Nanjing Tech University, Nanjing, China.; State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing Tech University, Nanjing, China.
Sha Y; College of Food Science and Light Industry, Nanjing Tech University, Nanjing, China.; State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing Tech University, Nanjing, China.
Wang R; College of Food Science and Light Industry, Nanjing Tech University, Nanjing, China.; State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing Tech University, Nanjing, China.
Xu Z; College of Food Science and Light Industry, Nanjing Tech University, Nanjing, China.; State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing Tech University, Nanjing, China.; State Key Laboratory of Biobased Material and Green Papermaking, Qilu University of Technology, Shandong Academy of Sciences, Jinan, China.
Xu X; College of Food Science and Light Industry, Nanjing Tech University, Nanjing, China.; State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing Tech University, Nanjing, China.
Li S; College of Food Science and Light Industry, Nanjing Tech University, Nanjing, China.; State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing Tech University, Nanjing, China.
Gao Z; State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing Tech University, Nanjing, China.
Xu H; College of Food Science and Light Industry, Nanjing Tech University, Nanjing, China.; State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing Tech University, Nanjing, China.
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Źródło :
Journal of the science of food and agriculture [J Sci Food Agric] 2021 Jan 30; Vol. 101 (2), pp. 693-702. Date of Electronic Publication: 2020 Aug 21.
Typ publikacji :
Journal Article
MeSH Terms :
Fructose/*chemistry
Glycoside Hydrolases/*chemistry
Inulin/*chemistry
Racemases and Epimerases/*chemistry
Recombinant Fusion Proteins/*chemistry
Biocatalysis ; Enzymes, Immobilized/chemistry ; Enzymes, Immobilized/genetics ; Enzymes, Immobilized/metabolism ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Food Technology/economics ; Glycoside Hydrolases/genetics ; Glycoside Hydrolases/metabolism ; Inulin/genetics ; Inulin/metabolism ; Recombinant Fusion Proteins/genetics ; Recombinant Fusion Proteins/metabolism
Czasopismo naukowe
Tytuł :
GDP-altrose as novel product of GDP-mannose 3,5-epimerase: Revisiting its reaction mechanism.
Autorzy :
Gevaert O; Centre for Synthetic Biology, Department of Biotechnology, Ghent University, Coupure Links 653, 9000 Gent, Belgium.
Van Overtveldt S; Centre for Synthetic Biology, Department of Biotechnology, Ghent University, Coupure Links 653, 9000 Gent, Belgium.
Da Costa M; Centre for Synthetic Biology, Department of Biotechnology, Ghent University, Coupure Links 653, 9000 Gent, Belgium.
Beerens K; Centre for Synthetic Biology, Department of Biotechnology, Ghent University, Coupure Links 653, 9000 Gent, Belgium.
Desmet T; Centre for Synthetic Biology, Department of Biotechnology, Ghent University, Coupure Links 653, 9000 Gent, Belgium. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2020 Dec 15; Vol. 165 (Pt B), pp. 1862-1868. Date of Electronic Publication: 2020 Oct 16.
Typ publikacji :
Journal Article
MeSH Terms :
Guanosine Diphosphate/*metabolism
Guanosine Diphosphate Mannose/*metabolism
Hexoses/*metabolism
Racemases and Epimerases/*metabolism
Biocatalysis ; Catalytic Domain ; Guanosine Diphosphate/chemistry ; Hexoses/chemistry ; Protein Engineering ; Substrate Specificity
Czasopismo naukowe

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