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Wyszukujesz frazę ""Radiation-Protective Agents"" wg kryterium: Temat


Tytuł :
Radioprotective effect of radiation-induced Lactococcus lactis cell-free extract against Coγ injury in mice.
Autorzy :
Suo K; School of Life Sciences, Zhengzhou University, Zhengzhou, Henan 450001, China.
Chen S; School of Life Sciences, Zhengzhou University, Zhengzhou, Henan 450001, China.
Li X; School of Life Sciences, Zhengzhou University, Zhengzhou, Henan 450001, China.
Liu X; School of Life Sciences, Zhengzhou University, Zhengzhou, Henan 450001, China.
Yi J; School of Life Sciences, Zhengzhou University, Zhengzhou, Henan 450001, China.
Zhu J; School of Life Sciences, Zhengzhou University, Zhengzhou, Henan 450001, China.
Lu L; Zhengzhou Mindtek Biological Technology Co. Ltd., Zhengzhou, Henan 450001, China.
Hao L; Institute of Quartermaster Engineering and Technology, Academy of Military Sciences PLA China, Beijing 100010, China. Electronic address: .
Kang Q; School of Life Sciences, Zhengzhou University, Zhengzhou, Henan 450001, China.
Lu J; School of Life Sciences, Zhengzhou University, Zhengzhou, Henan 450001, China. Electronic address: .
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Źródło :
Journal of dairy science [J Dairy Sci] 2021 Sep; Vol. 104 (9), pp. 9532-9542. Date of Electronic Publication: 2021 Jul 01.
Typ publikacji :
Journal Article
MeSH Terms :
Lactococcus lactis*
Radiation-Protective Agents*
Animals ; Antioxidants/metabolism ; Cell Extracts ; Hydrogen Peroxide/metabolism ; Liver/metabolism ; Mice ; Oxidative Stress
Czasopismo naukowe
Tytuł :
Could Polyphenols Really Be a Good Radioprotective Strategy?
Autorzy :
Faramarzi S; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania 'Luigi Vanvitelli', Via Vivaldi 43, 81100 Caserta, Italy.; Department of Plant Production and Genetics, Razi University, Kermanshah 67149-67346, Iran.
Piccolella S; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania 'Luigi Vanvitelli', Via Vivaldi 43, 81100 Caserta, Italy.
Manti L; Department of Physics E. Pancini, University of Naples 'Federico II', and Istituto Nazionale di Fisica Nucleare, (INFN), Naples Section, Monte S. Angelo, Via Cinthia, 80126 Napoli, Italy.
Pacifico S; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania 'Luigi Vanvitelli', Via Vivaldi 43, 81100 Caserta, Italy.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Aug 17; Vol. 26 (16). Date of Electronic Publication: 2021 Aug 17.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Polyphenols/*pharmacology
Radiation-Protective Agents/*pharmacology
Animals ; Humans ; Polyphenols/chemistry ; Radiation-Protective Agents/chemistry
Czasopismo naukowe
Tytuł :
Bellis perennis extract mitigates UVA-induced keratinocyte damage: Photoprotective and immunomodulatory effects.
Autorzy :
Souza de Carvalho VM; Universidade Federal de São Paulo (UNIFESP), Escola Paulista de Medicina, Departamento de Morfologia e Genética, São Paulo, SP, Brazil.
Covre JL; Universidade Federal de São Paulo (UNIFESP), Escola Paulista de Medicina, Departamento de Morfologia e Genética, São Paulo, SP, Brazil.
Correia-Silva RD; Universidade Federal de São Paulo (UNIFESP), Escola Paulista de Medicina, Departamento de Morfologia e Genética, São Paulo, SP, Brazil.
Lice I; Universidade Federal de São Paulo (UNIFESP), Escola Paulista de Medicina, Departamento de Morfologia e Genética, São Paulo, SP, Brazil.
Corrêa MP; Universidade Estadual Paulista (UNESP), Instituto de Biociências Letras e Ciências Exatas, Programa de Pós-Graduação em Biociências, São José do Rio Preto, SP, Brazil.
Leopoldino AM; Universidade de São Paulo (USP), Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Departamento de Análises Clínicas, Toxicológicas e Bromatológicas, Ribeirão Preto, SP, Brazil.
Gil CD; Universidade Federal de São Paulo (UNIFESP), Escola Paulista de Medicina, Departamento de Morfologia e Genética, São Paulo, SP, Brazil; Universidade Estadual Paulista (UNESP), Instituto de Biociências Letras e Ciências Exatas, Programa de Pós-Graduação em Biociências, São José do Rio Preto, SP, Brazil. Electronic address: .
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Źródło :
Journal of photochemistry and photobiology. B, Biology [J Photochem Photobiol B] 2021 Aug; Vol. 221, pp. 112247. Date of Electronic Publication: 2021 Jun 19.
Typ publikacji :
Journal Article
MeSH Terms :
Ultraviolet Rays*
Asteraceae/*chemistry
Immunomodulation/*drug effects
Plant Extracts/*pharmacology
Radiation-Protective Agents/*pharmacology
Asteraceae/metabolism ; Caspase 3/metabolism ; Catalase/metabolism ; Cell Line ; Cell Survival/drug effects ; Cell Survival/radiation effects ; Humans ; Immunomodulation/radiation effects ; Keratinocytes/cytology ; Keratinocytes/metabolism ; Plant Extracts/chemistry ; Radiation-Protective Agents/chemistry ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł :
The role of TLR4/NF-κB signaling in the radioprotective effects of exogenous Prdx6.
Autorzy :
Sharapov MG; Institute of Cell Biophysics of the Russian Academy of Sciences, PSCBR RAS, Pushchino, Russia. Electronic address: .
Glushkova OV; Institute of Cell Biophysics of the Russian Academy of Sciences, PSCBR RAS, Pushchino, Russia.
Parfenyuk SB; Institute of Cell Biophysics of the Russian Academy of Sciences, PSCBR RAS, Pushchino, Russia.
Gudkov SV; Prokhorov General Physics Institute of the Russian Academy of Sciences, Moscow, Russia.
Lunin SM; Institute of Cell Biophysics of the Russian Academy of Sciences, PSCBR RAS, Pushchino, Russia.
Novoselova EG; Institute of Cell Biophysics of the Russian Academy of Sciences, PSCBR RAS, Pushchino, Russia.
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Źródło :
Archives of biochemistry and biophysics [Arch Biochem Biophys] 2021 May 15; Vol. 702, pp. 108830. Date of Electronic Publication: 2021 Mar 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
NF-kappa B/*metabolism
Peroxiredoxin VI/*pharmacology
Radiation-Protective Agents/*pharmacology
Signal Transduction/*drug effects
Toll-Like Receptor 4/*metabolism
3T3 Cells ; Animals ; Apoptosis/drug effects ; Apoptosis/radiation effects ; Mice ; Models, Molecular ; Oxidative Stress/drug effects ; Oxidative Stress/radiation effects ; Peroxiredoxin VI/chemistry ; Peroxiredoxin VI/metabolism ; Protein Conformation ; Radiation-Protective Agents/chemistry ; Radiation-Protective Agents/metabolism ; Signal Transduction/radiation effects ; Toll-Like Receptor 4/chemistry
Czasopismo naukowe
Tytuł :
Radioprotective effects of Cryptosporidium parvum lysates on normal cells.
Autorzy :
Chaturvedi PK; Department of Radiation Oncology, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju 28644, Republic of Korea.
Erdenetuya E; Department of Radiation Oncology, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju 28644, Republic of Korea.
Prabakaran DS; Department of Radiation Oncology, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju 28644, Republic of Korea.
Woo CG; Department of Pathology, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju 28644, Republic of Korea.
Kim KH; Department of Radiation Oncology, Chungnam National University Hospital, Daejeon 35015, Republic of Korea.
Yu JR; Department of Environmental and Tropical Medicine, Konkuk University College of Medicine, Chungju 27478, Republic of Korea.
Park WY; Department of Radiation Oncology, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju 28644, Republic of Korea. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2021 May 01; Vol. 178, pp. 121-135. Date of Electronic Publication: 2021 Feb 23.
Typ publikacji :
Journal Article
MeSH Terms :
Radiation-Protective Agents*/chemistry
Radiation-Protective Agents*/pharmacology
Cell Survival/*drug effects
Cryptosporidium parvum/*metabolism
DNA Damage/*drug effects
Radiation Protection/*methods
Animals ; COS Cells ; Chlorocebus aethiops ; Gamma Rays/adverse effects ; HaCaT Cells ; Humans ; Subcellular Fractions
Czasopismo naukowe
Tytuł :
Effects of radiation and role of plants in radioprotection: A critical review.
Autorzy :
Dowlath MJH; Center for Environmental Nuclear Research, Directorate of Research, SRM Institute of Science and Technology, SRM Nagar, Kattankulathur, 603203, Kanchipuram, Chennai, Tamil Nadu, India.
Karuppannan SK; Center for Environmental Nuclear Research, Directorate of Research, SRM Institute of Science and Technology, SRM Nagar, Kattankulathur, 603203, Kanchipuram, Chennai, Tamil Nadu, India.
Sinha P; Project Management, Bioneeds India Pvt. Ltd, Peenya Industrial Area, Bengaluru 560058, India.
Dowlath NS; Department of Biochemistry, Ethiraj College for Women, Chennai, Tamil Nadu 600008, India.
Arunachalam KD; Center for Environmental Nuclear Research, Directorate of Research, SRM Institute of Science and Technology, SRM Nagar, Kattankulathur, 603203, Kanchipuram, Chennai, Tamil Nadu, India. Electronic address: .
Ravindran B; Department of Environmental Energy and Engineering, Kyonggi University Youngtong-Gu, Suwon, Gyeonggi-Do 16227, South Korea. Electronic address: .
Chang SW; Department of Environmental Energy and Engineering, Kyonggi University Youngtong-Gu, Suwon, Gyeonggi-Do 16227, South Korea.
Nguyen-Tri P; Département de Chimie, Biochimie et Physique, Université du Québec à Trois-Rivières (UQTR), Trois-Rivières, QC G8Z 4M3, Canada.
Nguyen DD; Faculty of Environmental and Food Engineering, Nguyen Tat Thanh University, 300A Nguyen Tat Thanh, District 4, Ho Chi Minh City, 755414, Vietnam; Department of Environmental Energy and Engineering, Kyonggi University Youngtong-Gu, Suwon, Gyeonggi-Do 16227, South Korea. Electronic address: .
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Źródło :
The Science of the total environment [Sci Total Environ] 2021 Jul 20; Vol. 779, pp. 146431. Date of Electronic Publication: 2021 Mar 13.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Radiation Injuries*
Radiation Protection*
Radiation-Protective Agents*
DNA Damage ; Humans ; Radiation, Ionizing
Czasopismo naukowe
Tytuł :
Synthesis and radioprotective effects of novel hybrid compounds containing edaravone analogue and 3-n-butylphthalide ring-opening derivatives.
Autorzy :
Li X; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College and Chinese Academy of Medical Science, Tianjin, China.
Wang X; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College and Chinese Academy of Medical Science, Tianjin, China.
Miao L; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College and Chinese Academy of Medical Science, Tianjin, China.
Liu Y; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College and Chinese Academy of Medical Science, Tianjin, China.
Lin X; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College and Chinese Academy of Medical Science, Tianjin, China.
Guo Y; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College and Chinese Academy of Medical Science, Tianjin, China.
Yuan R; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College and Chinese Academy of Medical Science, Tianjin, China.
Tian H; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College and Chinese Academy of Medical Science, Tianjin, China.
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Źródło :
Journal of cellular and molecular medicine [J Cell Mol Med] 2021 Jun; Vol. 25 (12), pp. 5470-5485. Date of Electronic Publication: 2021 May 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Benzofurans/*pharmacology
Edaravone/*pharmacology
Epithelial Cells/*drug effects
Intestine, Small/*drug effects
NF-E2-Related Factor 2/*metabolism
Radiation-Protective Agents/*pharmacology
Animals ; Apoptosis ; DNA Damage ; Edaravone/blood ; Epithelial Cells/metabolism ; Epithelial Cells/pathology ; Epithelial Cells/radiation effects ; Intestine, Small/metabolism ; Intestine, Small/pathology ; Intestine, Small/radiation effects ; Male ; Mice ; Mice, Inbred C57BL ; NF-E2-Related Factor 2/genetics ; Oxidative Stress ; Radiation-Protective Agents/chemistry ; Whole-Body Irradiation/adverse effects
Czasopismo naukowe
Tytuł :
Visible light. Part II: Photoprotection against visible and ultraviolet light.
Autorzy :
Geisler AN; CUNY School of Medicine, New York, New York.
Austin E; Department of Dermatology, Center for Photomedicine, SUNY Downstate Medical Center, Brooklyn, New York; Dermatology Service, VA New York Harbor Healthcare System, Brooklyn, New York.
Nguyen J; Department of Dermatology, Center for Photomedicine, SUNY Downstate Medical Center, Brooklyn, New York; Dermatology Service, VA New York Harbor Healthcare System, Brooklyn, New York.
Hamzavi I; Department of Dermatology, Photomedicine and Photobiology Unit, Henry Ford Health System, Detroit, Michigan.
Jagdeo J; Department of Dermatology, Center for Photomedicine, SUNY Downstate Medical Center, Brooklyn, New York; Dermatology Service, VA New York Harbor Healthcare System, Brooklyn, New York. Electronic address: .
Lim HW; Department of Dermatology, Photomedicine and Photobiology Unit, Henry Ford Health System, Detroit, Michigan.
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Źródło :
Journal of the American Academy of Dermatology [J Am Acad Dermatol] 2021 May; Vol. 84 (5), pp. 1233-1244. Date of Electronic Publication: 2021 Feb 25.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Erythema/*prevention & control
Radiation-Protective Agents/*administration & dosage
Skin Pigmentation/*drug effects
Sunlight/*adverse effects
Ultraviolet Rays/*adverse effects
Administration, Cutaneous ; Administration, Oral ; Erythema/etiology ; Humans ; Injections, Subcutaneous ; Radiation-Protective Agents/chemistry ; Skin/drug effects ; Skin/radiation effects ; Skin Pigmentation/radiation effects ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Pre-clinical evaluation of an innovative oral nano-formulation of baicalein for modulation of radiation responses.
Autorzy :
Joshi HA; Department of Pharmaceutical Sciences & Technology, Institute of Chemical Technology, Matunga, Mumbai 400019, India.
Patwardhan RS; Radiation Biology and Health Sciences Division, Modular Laboratories, Bhabha Atomic Research Centre, Trombay, Mumbai 400085, India. Electronic address: .
Sharma D; Radiation Biology and Health Sciences Division, Modular Laboratories, Bhabha Atomic Research Centre, Trombay, Mumbai 400085, India; Homi Bhabha National Institute, Anushaktinagar, Mumbai 400094, India.
Sandur SK; Radiation Biology and Health Sciences Division, Modular Laboratories, Bhabha Atomic Research Centre, Trombay, Mumbai 400085, India; Homi Bhabha National Institute, Anushaktinagar, Mumbai 400094, India.
Devarajan PV; Department of Pharmaceutical Sciences & Technology, Institute of Chemical Technology, Matunga, Mumbai 400019, India. Electronic address: .
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Źródło :
International journal of pharmaceutics [Int J Pharm] 2021 Feb 15; Vol. 595, pp. 120181. Date of Electronic Publication: 2020 Dec 24.
Typ publikacji :
Journal Article
MeSH Terms :
Flavanones/*administration & dosage
Flavanones/*pharmacology
Liposomes/*administration & dosage
Liposomes/*chemistry
Nanoparticles/*administration & dosage
Nanoparticles/*chemistry
Radiation Injuries, Experimental/*prevention & control
Radiation-Protective Agents/*administration & dosage
Radiation-Protective Agents/*pharmacology
A549 Cells ; Administration, Oral ; Animals ; Biological Availability ; Cell Death/drug effects ; Drug Compounding/methods ; Drug Evaluation, Preclinical ; Flavanones/pharmacokinetics ; Flavanones/therapeutic use ; Granulocytes/drug effects ; Humans ; Liposomes/pharmacokinetics ; Liposomes/therapeutic use ; Lymphocytes/drug effects ; Lymphocytes/enzymology ; Male ; Mice ; Mice, Inbred BALB C ; Nanoparticles/therapeutic use ; Radiation Tolerance/drug effects ; Radiation-Protective Agents/pharmacokinetics ; Radiation-Protective Agents/therapeutic use ; Radiotherapy/adverse effects ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł :
γ-Tocotrienol-Loaded Liposomes for Radioprotection from Hematopoietic Side Effects Caused by Radiotherapeutic Drugs.
Autorzy :
Lee SG; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
Kalidindi TM; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
Lou H; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, New York.
Gangangari K; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.; Department of Chemistry, Hunter College, City University of New York, New York, New York.
Punzalan B; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
Bitton A; New York University, New York, New York.
Lee CJ; New York University, New York, New York.
Vargas HA; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
Park S; Hunter College, New York, New York.
Bodei L; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
Kharas MG; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, New York.
Singh VK; Department of Pharmacology and Molecular Therapeutics, F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland.; Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, Maryland; and.
Kishore Pillarsetty NV; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.; Department of Radiology, Weill Cornell Medical College, New York, New York.
Larson SM; Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York .; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, New York.; Department of Radiology, Weill Cornell Medical College, New York, New York.
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Źródło :
Journal of nuclear medicine : official publication, Society of Nuclear Medicine [J Nucl Med] 2021 Apr; Vol. 62 (4), pp. 584-590. Date of Electronic Publication: 2020 Aug 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Chromans/*administration & dosage
Chromans/*pharmacology
Hematopoiesis/*drug effects
Hematopoiesis/*radiation effects
Radiation-Protective Agents/*administration & dosage
Radiation-Protective Agents/*pharmacology
Radiotherapy/*adverse effects
Vitamin E/*analogs & derivatives
Animals ; Chromans/pharmacokinetics ; Liposomes ; Mice ; Radiation-Protective Agents/pharmacokinetics ; Tissue Distribution ; Vitamin E/administration & dosage ; Vitamin E/pharmacokinetics ; Vitamin E/pharmacology
Czasopismo naukowe
Tytuł :
Role of Hypotaurine in Protection against UVA-Induced Damage in Keratinocytes.
Autorzy :
Baseggio Conrado A; Photobiology Unit, Ninewells Hospital & Medical School, University of Dundee, Dundee, UK.
Fanelli S; Department of Biochemical Sciences ' A. Rossi Fanelli', Sapienza University of Rome, Rome, Italy.
McGuire VA; Photobiology Unit, Ninewells Hospital & Medical School, University of Dundee, Dundee, UK.
Ibbotson SH; Photobiology Unit, Ninewells Hospital & Medical School, University of Dundee, Dundee, UK.
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Źródło :
Photochemistry and photobiology [Photochem Photobiol] 2021 Mar; Vol. 97 (2), pp. 353-359. Date of Electronic Publication: 2020 Oct 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Ultraviolet Rays*
Keratinocytes/*drug effects
Keratinocytes/*radiation effects
Radiation-Protective Agents/*pharmacology
Taurine/*analogs & derivatives
Cell Line ; Humans ; Radiation-Protective Agents/administration & dosage ; Radiation-Protective Agents/pharmacokinetics ; Sunscreening Agents/pharmacology ; Taurine/administration & dosage ; Taurine/pharmacokinetics ; Taurine/pharmacology
Czasopismo naukowe
Tytuł :
Preclinical Evaluation of Safety, Pharmacokinetics, Efficacy, and Mechanism of Radioprotective Agent HL-003.
Autorzy :
Liu Y; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College and Chinese Academy of Medical Science, Tianjin 300192, China.
Miao L; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College and Chinese Academy of Medical Science, Tianjin 300192, China.
Guo Y; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College and Chinese Academy of Medical Science, Tianjin 300192, China.
Tian H; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College and Chinese Academy of Medical Science, Tianjin 300192, China.
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Źródło :
Oxidative medicine and cellular longevity [Oxid Med Cell Longev] 2021 Feb 19; Vol. 2021, pp. 6683836. Date of Electronic Publication: 2021 Feb 19 (Print Publication: 2021).
Typ publikacji :
Journal Article
MeSH Terms :
Radiation-Protective Agents/*adverse effects
Radiation-Protective Agents/*pharmacokinetics
Administration, Oral ; Amifostine/adverse effects ; Amifostine/pharmacology ; Animals ; Apoptosis/drug effects ; Cell Differentiation/drug effects ; Cell Proliferation/drug effects ; DNA/radiation effects ; DNA Damage ; Dose-Response Relationship, Radiation ; Free Radical Scavengers/pharmacology ; Histones/metabolism ; Intestine, Small/pathology ; Male ; Mice, Inbred C57BL ; Mice, Inbred ICR ; Radiation-Protective Agents/administration & dosage ; Rats, Sprague-Dawley ; Regeneration/drug effects ; Signal Transduction/drug effects ; Survival Analysis ; Time Factors ; Toxicity Tests, Acute ; Treatment Outcome ; Whole-Body Irradiation
Czasopismo naukowe
Tytuł :
Polycysteine as a new type of radio-protector ameliorated tissue injury through inhibiting ferroptosis in mice.
Autorzy :
Zhang J; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Science & Peking Union Medical College, 300000, Tianjin, China.
Li K; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Science & Peking Union Medical College, 300000, Tianjin, China.
Zhang Q; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Science & Peking Union Medical College, 300000, Tianjin, China.
Zhu Z; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Science & Peking Union Medical College, 300000, Tianjin, China.
Huang G; KeChow Pharma, Inc., 201203, Shanghai, China.
Tian H; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Science & Peking Union Medical College, 300000, Tianjin, China. .
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Źródło :
Cell death & disease [Cell Death Dis] 2021 Feb 18; Vol. 12 (2), pp. 195. Date of Electronic Publication: 2021 Feb 18.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Ferroptosis/*drug effects
Hematopoietic Stem Cells/*drug effects
Intestinal Mucosa/*drug effects
Jejunum/*drug effects
Lung/*drug effects
Peptides/*pharmacology
Radiation Injuries/*prevention & control
Radiation-Protective Agents/*pharmacology
Amifostine/pharmacology ; Animals ; Cell Line ; DNA/metabolism ; Disease Models, Animal ; Ferroptosis/radiation effects ; Glutathione/metabolism ; Hematopoietic Stem Cells/metabolism ; Hematopoietic Stem Cells/pathology ; Hematopoietic Stem Cells/radiation effects ; Intestinal Mucosa/metabolism ; Intestinal Mucosa/pathology ; Intestinal Mucosa/radiation effects ; Jejunum/metabolism ; Jejunum/pathology ; Jejunum/radiation effects ; Lipid Peroxidation/drug effects ; Lung/metabolism ; Lung/pathology ; Lung/radiation effects ; Male ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Mice, Nude ; Oxidative Stress/drug effects ; Peptides/chemical synthesis ; Peptides/metabolism ; Radiation Dosage ; Radiation Injuries/genetics ; Radiation Injuries/metabolism ; Radiation Injuries/pathology ; Radiation-Protective Agents/chemical synthesis ; Radiation-Protective Agents/metabolism ; Rats ; Whole-Body Irradiation
Czasopismo naukowe
Tytuł :
Molecular Hydrogen as a Potential Clinically Applicable Radioprotective Agent.
Autorzy :
Hirano SI; Department of Research and Development, MiZ Company Limited, 2-19-15 Ofuna, Kamakura, Kanagawa 247-0056, Japan.
Ichikawa Y; Department of Research and Development, MiZ Company Limited, 2-19-15 Ofuna, Kamakura, Kanagawa 247-0056, Japan.
Sato B; Department of Research and Development, MiZ Company Limited, 2-19-15 Ofuna, Kamakura, Kanagawa 247-0056, Japan.
Yamamoto H; Department of Molecular & Cell Biology, University of California, Berkeley, 3060 Valley Life Sciences Bldg #3140, Berkeley, CA 94720-3140, USA.
Takefuji Y; Faculty of Environment and Information Studies, Keio University, 5322 Endo, Fujisawa 252-0882, Japan.
Satoh F; Department of Research and Development, MiZ Company Limited, 2-19-15 Ofuna, Kamakura, Kanagawa 247-0056, Japan.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Apr 27; Vol. 22 (9). Date of Electronic Publication: 2021 Apr 27.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Hydrogen/*pharmacology
Neoplasms/*therapy
Radiation Injuries/*prevention & control
Radiation-Protective Agents/*pharmacology
Animals ; Antioxidants/pharmacology ; Cognitive Dysfunction/etiology ; Cognitive Dysfunction/prevention & control ; Gastrointestinal Diseases/etiology ; Gastrointestinal Diseases/prevention & control ; Gene Expression Regulation/drug effects ; Gene Expression Regulation/radiation effects ; Humans ; Hydrogen/therapeutic use ; Immune System/drug effects ; Immune System/radiation effects ; Male ; Quality of Life ; Radiation-Protective Agents/therapeutic use ; Skin/drug effects ; Skin/radiation effects ; Spermatozoa/drug effects ; Spermatozoa/radiation effects
Czasopismo naukowe
Tytuł :
An injectable double-crosslinking iodinated composite hydrogel as a potential radioprotective spacer with durable imaging function.
Autorzy :
Wang C; College of Materials Science & Engineering, Zhejiang University of Technology, China. .
Wu L
Li W
Fei J
Xu J
Chen S
Yan S
Wang X
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Źródło :
Journal of materials chemistry. B [J Mater Chem B] 2021 Apr 21; Vol. 9 (15), pp. 3346-3356. Date of Electronic Publication: 2021 Apr 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Contrast Media/*chemistry
Cross-Linking Reagents/*chemistry
Hydrogels/*chemistry
Prostatic Neoplasms/*diagnostic imaging
Radiation-Protective Agents/*chemistry
Animals ; Contrast Media/chemical synthesis ; Cross-Linking Reagents/chemical synthesis ; Hydrogels/chemical synthesis ; Male ; Molecular Structure ; Radiation-Protective Agents/chemical synthesis ; Rats ; Rats, Sprague-Dawley ; Tomography, X-Ray Computed
Czasopismo naukowe
Tytuł :
Reviewing the recent advances in application of pectin for technical and health promotion purposes: From laboratory to market.
Autorzy :
Moslemi M; Halal Research Center of IRI, Iran Food and Drug Administration, Ministry of Health and Medical Education, Tehran, Iran. Electronic address: .
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Źródło :
Carbohydrate polymers [Carbohydr Polym] 2021 Feb 15; Vol. 254, pp. 117324. Date of Electronic Publication: 2020 Nov 15.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Constipation/*drug therapy
Drug Compounding/*methods
Food Packaging/*methods
Gastrointestinal Diseases/*drug therapy
Pectins/*therapeutic use
Radiation-Protective Agents/*therapeutic use
Tissue Engineering/*methods
Absorption, Physicochemical ; Digestion/drug effects ; Humans ; Metals, Heavy/chemistry ; Pectins/chemistry ; Radiation-Protective Agents/chemistry ; Solubility ; Transition Temperature
Czasopismo naukowe
Tytuł :
3,3'-Diselenodipropionic acid (DSePA): A redox active multifunctional molecule of biological relevance.
Autorzy :
Kunwar A; Radiation & Photochemistry Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400085, India; Homi Bhabha National Institute, Anushaktinagar, Mumbai 400094, India. Electronic address: .
Priyadarsini KI; UM-DAE Centre for Excellence in Basic Sciences, University of Mumbai, Kalina Campus, Santacruz (E), Mumbai 400098, India. Electronic address: .
Jain VK; UM-DAE Centre for Excellence in Basic Sciences, University of Mumbai, Kalina Campus, Santacruz (E), Mumbai 400098, India. Electronic address: .
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Źródło :
Biochimica et biophysica acta. General subjects [Biochim Biophys Acta Gen Subj] 2021 Jan; Vol. 1865 (1), pp. 129768. Date of Electronic Publication: 2020 Oct 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Antioxidants/*pharmacology
Propionates/*pharmacology
Radiation-Protective Agents/*pharmacology
Selenium Compounds/*pharmacology
Animals ; Antioxidants/chemical synthesis ; Antioxidants/pharmacokinetics ; Antioxidants/toxicity ; Humans ; Oxidation-Reduction/drug effects ; Propionates/chemical synthesis ; Propionates/pharmacokinetics ; Propionates/toxicity ; Radiation-Protective Agents/chemical synthesis ; Radiation-Protective Agents/pharmacokinetics ; Radiation-Protective Agents/toxicity ; Reactive Oxygen Species/metabolism ; S-Nitrosothiols/metabolism ; Selenium Compounds/chemical synthesis ; Selenium Compounds/pharmacokinetics ; Selenium Compounds/toxicity
Czasopismo naukowe
Tytuł :
High-throughput preparation of radioprotective polymers via Hantzsch's reaction for in vivo X-ray damage determination.
Autorzy :
Liu G; The Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing, 100084, China.
Zeng Y; The Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing, 100084, China.
Lv T; State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, 100084, China.
Mao T; The Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing, 100084, China.; Science and Technology on Advanced Ceramic Fibers and Composites Laboratory, National University of Defense Technology, Changsha, 410073, China.
Wei Y; The Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing, 100084, China.
Jia S; State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, 100084, China.
Gou Y; Science and Technology on Advanced Ceramic Fibers and Composites Laboratory, National University of Defense Technology, Changsha, 410073, China.
Tao L; The Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing, 100084, China. .
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Źródło :
Nature communications [Nat Commun] 2020 Dec 04; Vol. 11 (1), pp. 6214. Date of Electronic Publication: 2020 Dec 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
X-Rays*
Chemistry Techniques, Synthetic/*methods
Embryo, Nonmammalian/*radiation effects
Fibroblasts/*radiation effects
Polymers/*chemical synthesis
Radiation-Protective Agents/*chemical synthesis
Amifostine/pharmacology ; Animals ; Cell Line ; Cell Survival/drug effects ; Cell Survival/radiation effects ; Comet Assay ; DNA Damage/drug effects ; DNA Damage/radiation effects ; Embryo, Nonmammalian/drug effects ; Embryo, Nonmammalian/embryology ; Fibroblasts/cytology ; Fibroblasts/drug effects ; Mice ; Models, Chemical ; Molecular Structure ; Polymers/chemistry ; Polymers/pharmacology ; Radiation-Protective Agents/chemistry ; Radiation-Protective Agents/pharmacology ; Zebrafish/embryology
Czasopismo naukowe
Tytuł :
Trends in pharmacological stimulation of regeneration of ionizing radiation-damaged mammalian organism.
Autorzy :
Hofer M
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Transliterated Title :
Trendy ve farmakologické stimulaci regenerace ionizujícím zářením poškozeného savčího organismu.
Źródło :
Casopis lekaru ceskych [Cas Lek Cesk] 2020 Winter; Vol. 159 (7-8), pp. 275-280.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Acute Radiation Syndrome*/drug therapy
Radiation-Protective Agents*/pharmacology
Radiation-Protective Agents*/therapeutic use
Animals ; Granulocyte Colony-Stimulating Factor ; Humans ; Radiation, Ionizing ; Regeneration
Czasopismo naukowe
Tytuł :
Step gradient alcohol precipitation for the purification of low molecular weight fucoidan from Sargassum siliquastrum and its UVB protective effects.
Autorzy :
Fernando IPS; Department of Marine Bio-Food Sciences, Chonnam National University, Yeosu 59626, Republic of Korea.
Dias MKHM; Department of Food Technology and Nutrition, Chonnam National University, Yeosu 59626, Republic of Korea.
Madusanka DMD; Department of Food Technology and Nutrition, Chonnam National University, Yeosu 59626, Republic of Korea.
Han EJ; Department of Food Technology and Nutrition, Chonnam National University, Yeosu 59626, Republic of Korea.
Kim MJ; Department of Food Technology and Nutrition, Chonnam National University, Yeosu 59626, Republic of Korea.
Jeon YJ; Marine Science Institute, Jeju National University, Jeju Self-Governing Province 63333, Republic of Korea; Department of Marine Life Science, Jeju National University, Jeju 63243, Republic of Korea.
Ahn G; Department of Marine Bio-Food Sciences, Chonnam National University, Yeosu 59626, Republic of Korea; Department of Food Technology and Nutrition, Chonnam National University, Yeosu 59626, Republic of Korea. Electronic address: .
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2020 Nov 15; Vol. 163, pp. 26-35. Date of Electronic Publication: 2020 Jun 26.
Typ publikacji :
Journal Article
MeSH Terms :
Ethanol/*chemistry
Polysaccharides/*isolation & purification
Polysaccharides/*pharmacology
Radiation-Protective Agents/*isolation & purification
Radiation-Protective Agents/*pharmacology
Sargassum/*chemistry
Ultraviolet Rays/*adverse effects
Apoptosis/drug effects ; Cell Line, Transformed ; DNA Damage ; Fractional Precipitation/methods ; Heme Oxygenase-1/metabolism ; Humans ; Keratinocytes/cytology ; Keratinocytes/drug effects ; Keratinocytes/radiation effects ; Keratinocytes/ultrastructure ; Mitochondria/metabolism ; Molecular Weight ; Monosaccharides/analysis ; Monosaccharides/chemistry ; NF-E2-Related Factor 2/metabolism ; Oxidative Stress/drug effects ; Plant Extracts/chemistry ; Plant Extracts/isolation & purification ; Plant Extracts/pharmacology ; Polysaccharides/analysis ; Polysaccharides/chemistry ; Radiation-Protective Agents/chemistry ; Reactive Oxygen Species/metabolism
Czasopismo naukowe

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