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Wyszukujesz frazę ""Radiation-Protective Agents"" wg kryterium: Temat


Tytuł:
Scleroglucan protects the intestine from irradiation-induced injury by targeting the IL-17 signaling pathway.
Autorzy:
Huang D; School of Public Health and Management, Wenzhou Medical University, 325000 Wenzhou, China; Department of Radiation Medicine, Faculty of Naval Medicine, Naval Medical University, Shanghai 200433, China.
Wang Y; School of Public Health and Management, Wenzhou Medical University, 325000 Wenzhou, China; Department of Radiation Medicine, Faculty of Naval Medicine, Naval Medical University, Shanghai 200433, China.
Zhai X; School of Public Health and Management, Wenzhou Medical University, 325000 Wenzhou, China; Department of Radiation Medicine, Faculty of Naval Medicine, Naval Medical University, Shanghai 200433, China.
Shen Q; School of Public Health and Management, Wenzhou Medical University, 325000 Wenzhou, China.
Zhang L; School of Public Health and Management, Wenzhou Medical University, 325000 Wenzhou, China; Department of Radiation Medicine, Faculty of Naval Medicine, Naval Medical University, Shanghai 200433, China.
Fang D; Department of Radiation Medicine, Faculty of Naval Medicine, Naval Medical University, Shanghai 200433, China.
Fang L; Department of Radiation Medicine, Faculty of Naval Medicine, Naval Medical University, Shanghai 200433, China.
Zhang J; Department of Radiation Medicine, Faculty of Naval Medicine, Naval Medical University, Shanghai 200433, China.
Ma Y; Department of Radiation Medicine, Faculty of Naval Medicine, Naval Medical University, Shanghai 200433, China.
Chu C; Department of Radiation Medicine, Faculty of Naval Medicine, Naval Medical University, Shanghai 200433, China.
Liu G; Department of Radiation Medicine, Faculty of Naval Medicine, Naval Medical University, Shanghai 200433, China.
Cheng Y; Department of Radiation Medicine, Faculty of Naval Medicine, Naval Medical University, Shanghai 200433, China.
Liu C; Department of Radiation Medicine, Faculty of Naval Medicine, Naval Medical University, Shanghai 200433, China. Electronic address: .
Du J; Department of Radiation Medicine, Faculty of Naval Medicine, Naval Medical University, Shanghai 200433, China. Electronic address: .
Cai J; School of Public Health and Management, Wenzhou Medical University, 325000 Wenzhou, China; Department of Radiation Medicine, Faculty of Naval Medicine, Naval Medical University, Shanghai 200433, China. Electronic address: .
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Źródło:
International immunopharmacology [Int Immunopharmacol] 2024 Mar 10; Vol. 129, pp. 111614. Date of Electronic Publication: 2024 Feb 12.
Typ publikacji:
Journal Article
MeSH Terms:
Radiation Injuries*/prevention & control
Radiation-Protective Agents*/pharmacology
Radiation-Protective Agents*/therapeutic use
Glucans*
Mice ; Animals ; Interleukin-17 ; Mice, Inbred C57BL ; Signal Transduction ; Intestines/pathology
Czasopismo naukowe
Tytuł:
Histopathological studies of nonhuman primates exposed to supralethal doses of total- or partial-body radiation: influence of a medical countermeasure, gamma-tocotrienol.
Autorzy:
Singh VK; Division of Radioprotectants, Department of Pharmacology and Molecular Therapeutics, F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD, 20814-2712, USA. .; Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA. .
Wise SY; Division of Radioprotectants, Department of Pharmacology and Molecular Therapeutics, F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD, 20814-2712, USA.; Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA.
Fatanmi OO; Division of Radioprotectants, Department of Pharmacology and Molecular Therapeutics, F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD, 20814-2712, USA.; Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA.
Petrus SA; Division of Radioprotectants, Department of Pharmacology and Molecular Therapeutics, F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD, 20814-2712, USA.; Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA.
Carpenter AD; Division of Radioprotectants, Department of Pharmacology and Molecular Therapeutics, F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD, 20814-2712, USA.; Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, MD, 20814, USA.
Lee SH; Pathology Department, Research Services, Naval Medical Research Center, Silver Spring, MD, 20910, USA.
Hauer-Jensen M; Division of Radiation Health, Department of Pharmaceutical Sciences, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA.
Seed TM; Tech Micro Services, 4417 Maple Avenue, Bethesda, MD, 20814, USA.
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Źródło:
Scientific reports [Sci Rep] 2024 Mar 08; Vol. 14 (1), pp. 5757. Date of Electronic Publication: 2024 Mar 08.
Typ publikacji:
Journal Article
MeSH Terms:
Medical Countermeasures*
Acute Radiation Syndrome*/drug therapy
Acute Radiation Syndrome*/pathology
Radiation-Protective Agents*/pharmacology
Chromans*
Vitamin E/*analogs & derivatives
Animals ; United States ; Humans ; Vitamin E/pharmacology ; Disease Models, Animal ; Macaca mulatta
Czasopismo naukowe
Tytuł:
Prediction of Human Pharmacokinetics of E0703, a Novel Radioprotective Agent, Using Physiologically Based Pharmacokinetic Modeling and an Interspecies Extrapolation Approach.
Autorzy:
Ge YX; College of Chemistry and Life Science, Beijing University of Technology, Beijing 100124, China.; Department of Pharmacology and Toxicology, Beijing Institute of Radiation Medicine, Beijing 100850, China.
Zhang Z; Department of Pharmacology and Toxicology, Beijing Institute of Radiation Medicine, Beijing 100850, China.
Yan JY; Department of Pharmacology and Toxicology, Beijing Institute of Radiation Medicine, Beijing 100850, China.
Ma ZC; Department of Pharmacology and Toxicology, Beijing Institute of Radiation Medicine, Beijing 100850, China.
Wang YG; Department of Pharmacology and Toxicology, Beijing Institute of Radiation Medicine, Beijing 100850, China.
Xiao CR; Department of Pharmacology and Toxicology, Beijing Institute of Radiation Medicine, Beijing 100850, China.
Zhuang XM; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing 100850, China.
Gao Y; College of Chemistry and Life Science, Beijing University of Technology, Beijing 100124, China.; Department of Pharmacology and Toxicology, Beijing Institute of Radiation Medicine, Beijing 100850, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 06; Vol. 25 (5). Date of Electronic Publication: 2024 Mar 06.
Typ publikacji:
Journal Article
MeSH Terms:
Radiation-Protective Agents*
Mice ; Humans ; Animals ; Dogs ; Models, Biological ; Administration, Oral ; Tissue Distribution ; Pharmacokinetics
Czasopismo naukowe
Tytuł:
Safety evaluation of 5-hydroxytryptophan and S-(2-aminoethyl)isothiouronium bromide hydrobromide on rodent lungs.
Autorzy:
Thokchom SK; Drug Repurpose and Translational Lab, Department of CBRN, Institute of Nuclear Medicine and Allied Sciences (INMAS), Defence Research and Development Organisation (DRDO), Timarpur, Delhi, India.
Indracanti N
Khanna A
Indraganti PK
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Źródło:
Indian journal of pharmacology [Indian J Pharmacol] 2024 Jan 01; Vol. 56 (1), pp. 28-36. Date of Electronic Publication: 2024 Mar 08.
Typ publikacji:
Journal Article
MeSH Terms:
Radiation-Protective Agents*
Humans ; Mice ; Animals ; beta-Aminoethyl Isothiourea ; 5-Hydroxytryptophan ; Bromides/toxicity ; Isothiuronium ; Rodentia ; Mice, Inbred C57BL ; Lung ; Biomarkers ; Bronchoalveolar Lavage Fluid
Czasopismo naukowe
Tytuł:
N-acetyl-l-tryptophan (NAT) ameliorates radiation-induced cell death in murine macrophages J774A.1 via regulating redox homeostasis and mitochondrial dysfunction.
Autorzy:
Singh D; Institute of Nuclear Medicine and Allied Sciences, Delhi, India.
Malhotra P; Institute of Nuclear Medicine and Allied Sciences, Delhi, India.
Agarwal P; Institute of Nuclear Medicine and Allied Sciences, Delhi, India.
Kumar R; Institute of Nuclear Medicine and Allied Sciences, Delhi, India.
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Źródło:
Journal of biochemical and molecular toxicology [J Biochem Mol Toxicol] 2024 Jan; Vol. 38 (1), pp. e23529. Date of Electronic Publication: 2023 Sep 13.
Typ publikacji:
Journal Article
MeSH Terms:
Mitochondrial Diseases*/metabolism
Radiation-Protective Agents*/pharmacology
Animals ; Mice ; Tryptophan/pharmacology ; Tryptophan/metabolism ; Reactive Oxygen Species/metabolism ; Prospective Studies ; Cell Death ; Apoptosis ; Oxidative Stress ; Oxidation-Reduction ; Macrophages/metabolism ; Homeostasis ; Antioxidants/pharmacology
Czasopismo naukowe
Tytuł:
Advances of Amifostine in Radiation Protection: Administration and Delivery.
Autorzy:
Ji L; School of Pharmacy, Changzhou University, Changzhou 213164, Jiangsu, China.; School of Petroleum and Chemical Engineering, Changzhou University, Changzhou 213164, Jiangsu, China.
Cui P; School of Pharmacy, Changzhou University, Changzhou 213164, Jiangsu, China.
Zhou S; School of Pharmacy, Changzhou University, Changzhou 213164, Jiangsu, China.
Qiu L; School of Pharmacy, Changzhou University, Changzhou 213164, Jiangsu, China.
Huang H; School of Petroleum and Chemical Engineering, Changzhou University, Changzhou 213164, Jiangsu, China.
Wang C; School of Pharmacy, Changzhou University, Changzhou 213164, Jiangsu, China.
Wang J; School of Pharmacy, Changzhou University, Changzhou 213164, Jiangsu, China.
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Źródło:
Molecular pharmaceutics [Mol Pharm] 2023 Nov 06; Vol. 20 (11), pp. 5383-5395. Date of Electronic Publication: 2023 Sep 25.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Amifostine*/pharmacology
Amifostine*/therapeutic use
Radiation Protection*
Radiation-Protective Agents*/pharmacology
Drug-Related Side Effects and Adverse Reactions*
Humans ; Administration, Intravenous ; Adjuvants, Immunologic
Czasopismo naukowe
Tytuł:
Development of radiation countermeasure agents for acute radiation syndromes.
Autorzy:
Guan B; National Human Diseases Animal Model Resource Center, NHC Key Laboratory of Human Disease Comparative Medicine, Beijing Engineering Research Center for Experimental Animal Models of Human Critical Diseases, Institute of Laboratory Animal Sciences Chinese Academy of Medical Sciences (CAMS), Peking Union Medical College (PUMC), National Center of Technology Innovation for Animal Model, Beijing, China.
Li D; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Science, Peking Union Medical College, Tianjin, China.
Meng A; National Human Diseases Animal Model Resource Center, NHC Key Laboratory of Human Disease Comparative Medicine, Beijing Engineering Research Center for Experimental Animal Models of Human Critical Diseases, Institute of Laboratory Animal Sciences Chinese Academy of Medical Sciences (CAMS), Peking Union Medical College (PUMC), National Center of Technology Innovation for Animal Model, Beijing, China.
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Źródło:
Animal models and experimental medicine [Animal Model Exp Med] 2023 Aug; Vol. 6 (4), pp. 329-336. Date of Electronic Publication: 2023 Aug 29.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Acute Radiation Syndrome*/drug therapy
Acute Radiation Syndrome*/prevention & control
Civil Defense*
Drugs, Essential*
Medical Countermeasures*
Radiation-Protective Agents*/pharmacology
Radiation-Protective Agents*/therapeutic use
Animals ; Radiation, Ionizing
Czasopismo naukowe
Tytuł:
Obacunone Photoprotective Effects against Solar-Simulated Radiation-Induced Molecular Modifications in Primary Keratinocytes and Full-Thickness Human Skin.
Autorzy:
Montero P; Department of Pharmacology, Faculty of Medicine, University of Valencia, 46010 Valencia, Spain.; Faculty of Health Sciences, Universidad Europea de Valencia, 46185 Valencia, Spain.
Villarroel MJ; Department of Functional Biology and Physical Anthropology, Faculty of Biological Sciences, University of Valencia, 46010 Valencia, Spain.
Roger I; Department of Pharmacology, Faculty of Medicine, University of Valencia, 46010 Valencia, Spain.; Faculty of Health Sciences, Universidad Europea de Valencia, 46185 Valencia, Spain.; Biomedical Research Networking Centre on Respiratory Diseases (CIBERES), Health Institute Carlos III, 28029 Madrid, Spain.
Morell A; Department of Biochemical Sciences, Faculty of Pharmacy, Charles University, 50005 Hradec Králové, Czech Republic.
Milara J; Department of Pharmacology, Faculty of Medicine, University of Valencia, 46010 Valencia, Spain.; Biomedical Research Networking Centre on Respiratory Diseases (CIBERES), Health Institute Carlos III, 28029 Madrid, Spain.; Pharmacy Unit, University General Hospital Consortium, 46014 Valencia, Spain.
Cortijo J; Department of Pharmacology, Faculty of Medicine, University of Valencia, 46010 Valencia, Spain.; Biomedical Research Networking Centre on Respiratory Diseases (CIBERES), Health Institute Carlos III, 28029 Madrid, Spain.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jul 14; Vol. 24 (14). Date of Electronic Publication: 2023 Jul 14.
Typ publikacji:
Journal Article
MeSH Terms:
Sunburn*
Radiation-Protective Agents*/pharmacology
Humans ; NF-E2-Related Factor 2/genetics ; Ultraviolet Rays/adverse effects ; Keratinocytes ; Skin/pathology ; Inflammation/prevention & control ; Inflammation/pathology
Czasopismo naukowe
Tytuł:
Comparison of the radiation protection effect of different radiation protection aprons made of different materials.
Autorzy:
König AM; Philipps-University of Marburg, Clinic of Diagnostic and Interventional Radiology, Marburg, Germany. Electronic address: .
Verbe Zoum J; Philipps-University of Marburg, Clinic of Diagnostic and Interventional Radiology, Marburg, Germany.
Fiebich M; Philipps-University of Marburg, Clinic of Diagnostic and Interventional Radiology, Marburg, Germany; University of Applied Sciences, Institute of Medical Physics and Radiation Protection, Giessen, Germany.
Abissi PW; Philipps-University of Marburg, Clinic of Diagnostic and Interventional Radiology, Marburg, Germany; University of Applied Sciences, Institute of Medical Physics and Radiation Protection, Giessen, Germany.
Mahnken AH; Philipps-University of Marburg, Clinic of Diagnostic and Interventional Radiology, Marburg, Germany.
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Źródło:
European journal of radiology [Eur J Radiol] 2023 Jul; Vol. 164, pp. 110862. Date of Electronic Publication: 2023 May 08.
Typ publikacji:
Journal Article
MeSH Terms:
Radiation Protection*/methods
Radiation-Protective Agents*
Humans ; Radiation Dosage ; X-Rays ; Protective Clothing
Czasopismo naukowe
Tytuł:
Radioprotective role of amifostine on osteointegration of titanium implants in the tibia of rats.
Autorzy:
Aydemir Celep N; Ataturk University, Department of Medical Pharmacology, Erzurum 25240, Turkey.; Atatürk University, Faculty of Veterinary, Department of Histology and Embryology, Erzurum 25240, Turkey.
Kara H; Atatürk University, Faculty of Veterinary, Department of Anatomy, Erzurum 25240, Turkey.
Erbaş E; Atatürk University, Faculty of Veterinary, Department of Histology and Embryology, Erzurum 25240, Turkey. .
Doğan E; Kastamonu University, Faculty of Veterinary, Department of Surgery, Kastamonu 37200, Turkey.
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Źródło:
Journal of veterinary science [J Vet Sci] 2023 May; Vol. 24 (3), pp. e35.
Typ publikacji:
Journal Article
MeSH Terms:
Amifostine*/pharmacology
Amifostine*/therapeutic use
Radiation-Protective Agents*/pharmacology
Radiation-Protective Agents*/therapeutic use
Rats ; Male ; Animals ; Tibia ; Titanium ; Rats, Wistar
Czasopismo naukowe
Tytuł:
Alpha-thiol deoxynucleotide triphosphates (S-dNTPs) as radioprotective agents: A novel approach.
Autorzy:
Bruno JG; Nanohmics Inc., 6201 E. Oltorf Street, Suite 400, Austin, TX, 78741, USA. Electronic address: .
Sivils JC; Nanohmics Inc., 6201 E. Oltorf Street, Suite 400, Austin, TX, 78741, USA.
Mohan S; University of Texas Health Science Center at San Antonio, Department of Pathology & Laboratory Medicine, 7703 Floyd Curl Drive, San Antonio, TX, 78229, USA.
Natarajan M; University of Texas Health Science Center at San Antonio, Department of Pathology & Laboratory Medicine, 7703 Floyd Curl Drive, San Antonio, TX, 78229, USA.
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Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2023 Jun 11; Vol. 660, pp. 6-12. Date of Electronic Publication: 2023 Apr 05.
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Radiation-Protective Agents*/pharmacology
Humans ; Sulfhydryl Compounds/pharmacology ; DNA ; DNA Damage ; Nucleotides ; Antioxidants
Czasopismo naukowe
Tytuł:
Xerostomia: From Pharmacological Treatments to Traditional Medicine-An Overview on the Possible Clinical Management and Prevention Using Systemic Approaches.
Autorzy:
Sardellitti L; Department of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.; Dental Unit, Head and Neck Department, Azienda Ospedaliero Universitaria, 07100 Sassari, Italy.
Bortone A; Dental Unit, Head and Neck Department, Azienda Ospedaliero Universitaria, 07100 Sassari, Italy.
Filigheddu E; Dental Unit, Head and Neck Department, Azienda Ospedaliero Universitaria, 07100 Sassari, Italy.
Serralutzu F; Institute for Animal Production Systems in the Mediterranean Environment (ISPAAM)-Section of Sassari, 07100 Sassari, Italy.
Milia EP; Department of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.; Dental Unit, Head and Neck Department, Azienda Ospedaliero Universitaria, 07100 Sassari, Italy.
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Źródło:
Current oncology (Toronto, Ont.) [Curr Oncol] 2023 Apr 24; Vol. 30 (5), pp. 4412-4426. Date of Electronic Publication: 2023 Apr 24.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Radiation-Protective Agents*/adverse effects
Xerostomia*/drug therapy
Xerostomia*/etiology
Amifostine*/adverse effects
Humans ; Antioxidants ; Medicine, Traditional/adverse effects
Czasopismo naukowe
Tytuł:
Analysis of the Proteomic Profile in Serum of Irradiated Nonhuman Primates Treated with Ex-Rad, a Radiation Medical Countermeasure.
Autorzy:
Carpenter AD; Division of Radioprotectants, Department of Pharmacology and Molecular Therapeutics, F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, United States.; Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, United States.
Li Y; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, District of Columbia 20057, United States.
Janocha BL; Division of Radioprotectants, Department of Pharmacology and Molecular Therapeutics, F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, United States.; Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, United States.
Wise SY; Division of Radioprotectants, Department of Pharmacology and Molecular Therapeutics, F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, United States.; Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, United States.
Fatanmi OO; Division of Radioprotectants, Department of Pharmacology and Molecular Therapeutics, F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, United States.; Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, United States.
Maniar M; Onconova Therapeutics, Inc., 375 Pheasant Run, Newtown, Pennsylvania 18940, United States.
Cheema AK; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, District of Columbia 20057, United States.; Department of Biochemistry, Molecular and Cellular Biology, Georgetown University Medical Center, Washington, District of Columbia 20057, United States.
Singh VK; Division of Radioprotectants, Department of Pharmacology and Molecular Therapeutics, F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, United States.; Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, United States.
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Źródło:
Journal of proteome research [J Proteome Res] 2023 Apr 07; Vol. 22 (4), pp. 1116-1126. Date of Electronic Publication: 2023 Mar 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Medical Countermeasures*
Radiation-Protective Agents*/pharmacology
United States ; Animals ; Mice ; Proteomics ; Primates
Czasopismo naukowe
Tytuł:
Radioprotective countermeasures for radiation injury (Review).
Autorzy:
Liu L; National Health Commission Key Laboratory of Radiobiology, School of Public Health of Jilin University, Jilin, Changchun 130021, P.R. China.
Liang Z; School of Public Health, Xinxiang Medical University, Xinxiang 453003, P.R. China.
Ma S; School of Public Health and Management, Wenzhou Medical University, Wenzhou, Zhejiang 325035, P.R. China.
Li L; School of Public Health and Management, Wenzhou Medical University, Wenzhou, Zhejiang 325035, P.R. China.
Liu X; National Health Commission Key Laboratory of Radiobiology, School of Public Health of Jilin University, Jilin, Changchun 130021, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2023 Mar; Vol. 27 (3). Date of Electronic Publication: 2023 Feb 17.
Typ publikacji:
Review; Journal Article
MeSH Terms:
Radiation Injuries*/drug therapy
Radiation Injuries*/prevention & control
Radiation Protection*/methods
Radiation-Protective Agents*/pharmacology
Radiation-Protective Agents*/therapeutic use
Humans ; Radiation, Ionizing
Czasopismo naukowe
Tytuł:
Combination of natural polyphenols with a precursor of NAD and a TLR2/6 ligand lipopeptide protects mice against lethal γ radiation.
Autorzy:
Obrador E; Department of Physiology, Faculty of Medicine & Odontology, University of Valencia, 46010 Valencia, Spain. Electronic address: .
Salvador-Palmer R; Department of Physiology, Faculty of Medicine & Odontology, University of Valencia, 46010 Valencia, Spain.
Pellicer B; Service of Radiology, Sagunto Hospital, 46520 Sagunto, Valencia, Spain.
López-Blanch R; Department of Physiology, Faculty of Medicine & Odontology, University of Valencia, 46010 Valencia, Spain.
Sirerol JA; Department of Physiology, Faculty of Medicine & Odontology, University of Valencia, 46010 Valencia, Spain.
Villaescusa JI; Service of Radiological Protection, Health Research Institute (IISLaFe), La Fe University Hospital, 46026 Valencia, Spain; Biomedical Imaging Research Group GIBI230, Health Research Institute (IISLaFe), La Fe University Hospital, 46026 Valencia, Spain.
Montoro A; Service of Radiological Protection, Health Research Institute (IISLaFe), La Fe University Hospital, 46026 Valencia, Spain; Biomedical Imaging Research Group GIBI230, Health Research Institute (IISLaFe), La Fe University Hospital, 46026 Valencia, Spain.
Dellinger RW; Elysium Health Inc., New York, NY, 10013, USA.
Estrela JM; Department of Physiology, Faculty of Medicine & Odontology, University of Valencia, 46010 Valencia, Spain. Electronic address: .
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Źródło:
Journal of advanced research [J Adv Res] 2023 Mar; Vol. 45, pp. 73-86. Date of Electronic Publication: 2022 May 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
NAD*
Radiation-Protective Agents*/pharmacology
Radiation-Protective Agents*/therapeutic use
Mice ; Animals ; Gamma Rays ; Antioxidants ; Toll-Like Receptor 2/agonists ; Lipopeptides ; Polyphenols/pharmacology ; NF-E2-Related Factor 2 ; Chromatography, Liquid ; Ligands ; Tandem Mass Spectrometry ; Mammals
Czasopismo naukowe
Tytuł:
Safety, Pharmacokinetics, and Biomarkers of an Amorphous Solid Dispersion of Genistein, a Radioprotectant, in Healthy Volunteers.
Autorzy:
Serebrenik AA; Humanetics Corporation, Minneapolis, Minnesota, USA.
Verduyn CW; Medical Monitoring Consultancy, LLC, St. Paul, Minnesota, USA.
Kaytor MD; Humanetics Corporation, Minneapolis, Minnesota, USA.
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Źródło:
Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2023 Feb; Vol. 12 (2), pp. 190-201. Date of Electronic Publication: 2022 Oct 27.
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Genistein*/adverse effects
Genistein*/blood
Genistein*/pharmacokinetics
Radiation-Protective Agents*/adverse effects
Radiation-Protective Agents*/pharmacokinetics
Humans ; Biological Availability ; Biomarkers/blood ; Drug Compounding/methods ; Healthy Volunteers
Czasopismo naukowe
Tytuł:
Protective mechanism of a novel aminothiol compound on radiation-induced intestinal injury.
Autorzy:
Wang X; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine Institute of Radiation Medicine, Peking Union Medical College and Chinese Academy of Medical Science, Tianjin, China.
Yuan R; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine Institute of Radiation Medicine, Peking Union Medical College and Chinese Academy of Medical Science, Tianjin, China.
Miao L; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine Institute of Radiation Medicine, Peking Union Medical College and Chinese Academy of Medical Science, Tianjin, China.
Li X; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine Institute of Radiation Medicine, Peking Union Medical College and Chinese Academy of Medical Science, Tianjin, China.
Guo Y; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine Institute of Radiation Medicine, Peking Union Medical College and Chinese Academy of Medical Science, Tianjin, China.
Tian H; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine Institute of Radiation Medicine, Peking Union Medical College and Chinese Academy of Medical Science, Tianjin, China.
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Źródło:
International journal of radiation biology [Int J Radiat Biol] 2023; Vol. 99 (2), pp. 259-269. Date of Electronic Publication: 2022 May 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Radiation Injuries, Experimental*/drug therapy
Radiation Injuries, Experimental*/prevention & control
Radiation Injuries, Experimental*/metabolism
Radiation-Protective Agents*/pharmacology
Radiation-Protective Agents*/chemistry
Mice ; Animals ; Tumor Suppressor Protein p53/metabolism ; Intestine, Small ; Intestinal Mucosa/metabolism ; Intestinal Mucosa/radiation effects ; Radiation, Ionizing ; Apoptosis/radiation effects ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł:
Radioprotective effect of mistletoe extract on intestinal toxicity: in vivo study using adult zebrafish.
Autorzy:
Park S; Department of Radiation Oncology, Korea University Ansan Hospital, Gyeonggido, Republic of Korea.
Kim S; Department of Biomedical Sciences, College of Medicine, Korea University, Seoul, Republic of Korea.; Zebrafish Translational Medical Research Center, Korea University, Ansan, Republic of Korea.
Koun S; Zebrafish Translational Medical Research Center, Korea University, Ansan, Republic of Korea.
Park HC; Department of Biomedical Sciences, College of Medicine, Korea University, Seoul, Republic of Korea.; Zebrafish Translational Medical Research Center, Korea University, Ansan, Republic of Korea.
Yoon WS; Department of Radiation Oncology, Korea University Ansan Hospital, Gyeonggido, Republic of Korea.; Department of Radiation Oncology, College of Medicine, Korea University, Seoul, Republic of Korea.
Rim CH; Department of Radiation Oncology, Korea University Ansan Hospital, Gyeonggido, Republic of Korea.; Department of Radiation Oncology, College of Medicine, Korea University, Seoul, Republic of Korea.
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Źródło:
International journal of radiation biology [Int J Radiat Biol] 2023; Vol. 99 (5), pp. 845-852. Date of Electronic Publication: 2022 Nov 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Amifostine*
Mistletoe*
Radiation-Protective Agents*/pharmacology
Radiation-Protective Agents*/therapeutic use
Animals ; Zebrafish ; Plant Extracts/pharmacology ; Plant Extracts/therapeutic use ; Intestines
Czasopismo naukowe
Tytuł:
Review of compounds that exhibit radioprotective and/or mitigatory effects after application of diagnostic or therapeutic ionizing radiation.
Autorzy:
Zivkovic Radojevic M; Centre for Radiation Oncology, University Clinical Centre Kragujevac, Kragujevac, Serbia.
Milosavljevic N; Centre for Radiation Oncology, University Clinical Centre Kragujevac, Kragujevac, Serbia.
Miladinovic TB; Department of Science, Institute for Information Technologies, University of Kragujevac, Kragujevac, Serbia.
Janković S; Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.; Clinical Pharmacology Department, University Clinical Centre Kragujevac, Kragujevac, Serbia.
Folic M; Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.; Clinical Pharmacology Department, University Clinical Centre Kragujevac, Kragujevac, Serbia.
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Źródło:
International journal of radiation biology [Int J Radiat Biol] 2023; Vol. 99 (4), pp. 594-603. Date of Electronic Publication: 2022 Aug 17.
Typ publikacji:
Review; Journal Article
MeSH Terms:
Radiation-Protective Agents*/pharmacology
Radiation-Protective Agents*/therapeutic use
Radiation Protection*/methods
Radiation Injuries*/etiology
Radiation Injuries*/prevention & control
Radiation Injuries*/drug therapy
Humans ; Radiation, Ionizing
Czasopismo naukowe
Tytuł:
Molecular Influence of the ATM Protein in the Treatment of Human Cells with Different Radioprotective Drugs: Comparisons between Antioxidative and Pro-Episkevic Strategies.
Autorzy:
Restier-Verlet J; INSERM U1296 Unit 'Radiation: Defense, Health, Environment', Centre Léon-Bérard, 69008 Lyon, France.
Drouet M; INSERM U1296 Unit 'Radiation: Defense, Health, Environment', Centre Léon-Bérard, 69008 Lyon, France.; Division Défense NRBC, Institut de Recherche Biomédicale des Armées, 91220 Brétigny-sur-Orge, France.
Pras P; INSERM U1296 Unit 'Radiation: Defense, Health, Environment', Centre Léon-Bérard, 69008 Lyon, France.
Ferlazzo ML; INSERM U1296 Unit 'Radiation: Defense, Health, Environment', Centre Léon-Bérard, 69008 Lyon, France.
Granzotto A; INSERM U1296 Unit 'Radiation: Defense, Health, Environment', Centre Léon-Bérard, 69008 Lyon, France.
Sonzogni L; INSERM U1296 Unit 'Radiation: Defense, Health, Environment', Centre Léon-Bérard, 69008 Lyon, France.
Al-Choboq J; INSERM U1296 Unit 'Radiation: Defense, Health, Environment', Centre Léon-Bérard, 69008 Lyon, France.
El Nachef L; INSERM U1296 Unit 'Radiation: Defense, Health, Environment', Centre Léon-Bérard, 69008 Lyon, France.
François S; INSERM U1296 Unit 'Radiation: Defense, Health, Environment', Centre Léon-Bérard, 69008 Lyon, France.; Division Défense NRBC, Institut de Recherche Biomédicale des Armées, 91220 Brétigny-sur-Orge, France.
Bourguignon M; INSERM U1296 Unit 'Radiation: Defense, Health, Environment', Centre Léon-Bérard, 69008 Lyon, France.; Department of Biophysics and Nuclear Medicine, Université Paris Saclay Versailles St Quentin en Yvelines, 78035 Versailles, France.
Foray N; INSERM U1296 Unit 'Radiation: Defense, Health, Environment', Centre Léon-Bérard, 69008 Lyon, France.
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Źródło:
Biomolecules [Biomolecules] 2023 Mar 13; Vol. 13 (3). Date of Electronic Publication: 2023 Mar 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Radiation-Protective Agents*/pharmacology
Amifostine*/pharmacology
Animals ; Humans ; Ataxia Telangiectasia Mutated Proteins/metabolism ; DNA Breaks, Double-Stranded ; Antioxidants/pharmacology ; DNA Repair ; Mammals/metabolism
Czasopismo naukowe

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