PlzA is a bifunctional c-di-GMP biosensor that promotes tick and mammalian host-adaptation of Borrelia burgdorferi.
Autorzy:
Groshong AM; Department of Medicine, UConn Health, Farmington, Connecticut, United States of America.; Department of Pediatrics, UConn Health, Farmington, Connecticut, United States of America. Grassmann AA; Department of Medicine, UConn Health, Farmington, Connecticut, United States of America. Luthra A; Department of Medicine, UConn Health, Farmington, Connecticut, United States of America. McLain MA; Department of Medicine, UConn Health, Farmington, Connecticut, United States of America. Provatas AA; Center for Environmental Sciences and Engineering, University of Connecticut, Storrs, Connecticut, United States of America. RadolfJD; Department of Medicine, UConn Health, Farmington, Connecticut, United States of America.; Department of Pediatrics, UConn Health, Farmington, Connecticut, United States of America.; Department of Molecular Biology and Biophysics, UConn Health, Farmington, Connecticut, United States of America.; Department of Genetics and Genome Science, UConn Health, Farmington, Connecticut, United States of America.; Department of Immunology, UConn Health, Farmington, Connecticut, United States of America. Caimano MJ; Department of Medicine, UConn Health, Farmington, Connecticut, United States of America.; Department of Pediatrics, UConn Health, Farmington, Connecticut, United States of America.; Department of Molecular Biology and Biophysics, UConn Health, Farmington, Connecticut, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2021 Jul 15; Vol. 17 (7), pp. e1009725. Date of Electronic Publication: 2021 Jul 15 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Macrophage mediated recognition and clearance of Borrelia burgdorferi elicits MyD88-dependent and -independent phagosomal signals that contribute to phagocytosis and inflammation.
Autorzy:
Benjamin SJ; Department of Pediatrics, UConn Health, Farmington, CT, 06030, USA.; Department of Immunology, UConn Health, Farmington, CT, 06030, USA. Hawley KL; Department of Pediatrics, UConn Health, Farmington, CT, 06030, USA.; Division of Infectious Diseases, Connecticut Children's, Hartford, CT, 06106, USA. Vera-Licona P; Department of Pediatrics, UConn Health, Farmington, CT, 06030, USA.; Center for Quantitative Medicine, UConn Health, Farmington, CT, 06030, USA.; Department of Cell Biology, UConn Health, Farmington, CT, 06030, USA.; Institute of Systems Genomics, UConn Health, Farmington, CT, 06030, USA. La Vake CJ; Department of Pediatrics, UConn Health, Farmington, CT, 06030, USA. Cervantes JL; Department of Pediatrics, UConn Health, Farmington, CT, 06030, USA.; Division of Infectious Diseases, Connecticut Children's, Hartford, CT, 06106, USA.; Present Address: Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso, TX, 79905, USA. Ruan Y; The Jackson Laboratory for Genomic Medicine, Farmington, CT, 06032, USA. RadolfJD; Department of Pediatrics, UConn Health, Farmington, CT, 06030, USA.; Department of Immunology, UConn Health, Farmington, CT, 06030, USA.; Department of Medicine, UConn Health, Farmington, CT, 06030, USA.; Department of Molecular Biology and Biophysics, UConn Health, Farmington, CT, 06030, USA.; Department of Genetics and Genomic Sciences, UConn Health, Farmington, CT, 06030, USA. Salazar JC; Department of Pediatrics, UConn Health, Farmington, CT, 06030, USA. .; Department of Immunology, UConn Health, Farmington, CT, 06030, USA. .; Division of Infectious Diseases, Connecticut Children's, Hartford, CT, 06106, USA. .; Department of Medicine, UConn Health, Farmington, CT, 06030, USA. .; Division of Pediatric Infectious Diseases and Immunology, Connecticut Children's, 282 Washington Street, Hartford, CT, 06106, USA. .
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Źródło:
BMC immunology [BMC Immunol] 2021 May 17; Vol. 22 (1), pp. 32. Date of Electronic Publication: 2021 May 17.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Host-specific functional compartmentalization within the oligopeptide transporter during the Borrelia burgdorferi enzootic cycle.
Autorzy:
Groshong AM; Department of Medicine, UConn Health, Farmington, Connecticut, United States of America.; Department of Pediatrics, UConn Health, Farmington, Connecticut, United States of America. McLain MA; Department of Medicine, UConn Health, Farmington, Connecticut, United States of America. RadolfJD; Department of Medicine, UConn Health, Farmington, Connecticut, United States of America.; Department of Pediatrics, UConn Health, Farmington, Connecticut, United States of America.; Department of Molecular Biology and Biophysics, UConn Health, Farmington, Connecticut, United States of America.; Department of Genetics and Genome Science, UConn Health, Farmington, Connecticut, United States of America.; Department of Immunology, UConn Health, Farmington, Connecticut, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2021 Jan 11; Vol. 17 (1), pp. e1009180. Date of Electronic Publication: 2021 Jan 11 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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