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Wyświetlanie 1-8 z 8
Tytuł :
Redirected nuclear glutamate dehydrogenase supplies Tet3 with α-ketoglutarate in neurons.
Autorzy :
Traube FR; Department of Chemistry, Ludwig-Maximilians-Universität München, Munich, Germany.
Özdemir D; Department of Chemistry, Ludwig-Maximilians-Universität München, Munich, Germany.
Sahin H; Department of Chemistry, Ludwig-Maximilians-Universität München, Munich, Germany.
Scheel C; Department of Pharmacy - Center for Drug Research, Ludwig-Maximilians-Universität München, Munich, Germany.
Glück AF; Department of Chemistry, Ludwig-Maximilians-Universität München, Munich, Germany.
Geserich AS; Department of Pharmacy - Center for Drug Research, Ludwig-Maximilians-Universität München, Munich, Germany.
Oganesian S; Department of Chemistry, Ludwig-Maximilians-Universität München, Munich, Germany.
Kostidis S; Leiden University Medical Center, Center for Proteomics and Metabolomics, Leiden, The Netherlands.
Iwan K; Department of Chemistry, Ludwig-Maximilians-Universität München, Munich, Germany.
Rahimoff R; Department of Chemistry, Ludwig-Maximilians-Universität München, Munich, Germany.
Giorgio G; Department of Pharmacy - Center for Drug Research, Ludwig-Maximilians-Universität München, Munich, Germany.
Müller M; Department of Chemistry, Ludwig-Maximilians-Universität München, Munich, Germany.
Spada F; Department of Chemistry, Ludwig-Maximilians-Universität München, Munich, Germany.
Biel M; Department of Pharmacy - Center for Drug Research, Ludwig-Maximilians-Universität München, Munich, Germany.
Cox J; Computational Systems Biochemistry, Max Planck Institute of Biochemistry, Martinsried, Germany.
Giera M; Leiden University Medical Center, Center for Proteomics and Metabolomics, Leiden, The Netherlands.
Michalakis S; Department of Pharmacy - Center for Drug Research, Ludwig-Maximilians-Universität München, Munich, Germany. .; Department of Ophthalmology, University Hospital, LMU Munich, Munich, Germany. .
Carell T; Department of Chemistry, Ludwig-Maximilians-Universität München, Munich, Germany. .
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Źródło :
Nature communications [Nat Commun] 2021 Jul 02; Vol. 12 (1), pp. 4100. Date of Electronic Publication: 2021 Jul 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Nucleus/*enzymology
Cell Nucleus/*metabolism
Dioxygenases/*metabolism
Glutamate Dehydrogenase/*metabolism
Ketoglutaric Acids/*metabolism
Neurons/*metabolism
Animals ; Brain/metabolism ; Citric Acid Cycle ; Dioxygenases/genetics ; Epigenomics ; Gene Expression ; Glutamate Dehydrogenase/genetics ; Glutamic Acid/metabolism ; HEK293 Cells ; Humans ; Ketoglutarate Dehydrogenase Complex/metabolism ; Metabolomics ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mitochondria/metabolism ; Neuronal Plasticity
Czasopismo naukowe
Tytuł :
Active turnover of genomic methylcytosine in pluripotent cells.
Autorzy :
Spada F; Department of Chemistry, Ludwig Maximilians University Munich and Center for Integrated Protein Science Munich (CIPSM), Munich, Germany. .
Schiffers S; Department of Chemistry, Ludwig Maximilians University Munich and Center for Integrated Protein Science Munich (CIPSM), Munich, Germany.; National Cancer Institute, Center for Cancer Research, Bethesda, MD, USA.
Kirchner A; Department of Chemistry, Ludwig Maximilians University Munich and Center for Integrated Protein Science Munich (CIPSM), Munich, Germany.; Cancer Research UK Cambridge Institute, Cambridge, UK.
Zhang Y; Department of Chemistry, Ludwig Maximilians University Munich and Center for Integrated Protein Science Munich (CIPSM), Munich, Germany.; State Key Laboratory of Elemento-organic Chemistry and Department of Chemical Biology, College of Chemistry, Nankai University, Tianjin, China.
Arista G; Department of Chemistry, Ludwig Maximilians University Munich and Center for Integrated Protein Science Munich (CIPSM), Munich, Germany.
Kosmatchev O; Department of Chemistry, Ludwig Maximilians University Munich and Center for Integrated Protein Science Munich (CIPSM), Munich, Germany.
Korytiakova E; Department of Chemistry, Ludwig Maximilians University Munich and Center for Integrated Protein Science Munich (CIPSM), Munich, Germany.
Rahimoff R; Department of Chemistry, Ludwig Maximilians University Munich and Center for Integrated Protein Science Munich (CIPSM), Munich, Germany.; Department of Chemistry, University of California, Los Angeles, Berkeley, CA, USA.
Ebert C; Department of Chemistry, Ludwig Maximilians University Munich and Center for Integrated Protein Science Munich (CIPSM), Munich, Germany.
Carell T; Department of Chemistry, Ludwig Maximilians University Munich and Center for Integrated Protein Science Munich (CIPSM), Munich, Germany. .
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Źródło :
Nature chemical biology [Nat Chem Biol] 2020 Dec; Vol. 16 (12), pp. 1411-1419. Date of Electronic Publication: 2020 Aug 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA Repair*
Epigenesis, Genetic*
Genome*
5-Methylcytosine/*metabolism
Deoxycytidine/*analogs & derivatives
Pluripotent Stem Cells/*metabolism
Animals ; Carbon Isotopes ; Cell Line ; DNA/genetics ; DNA/metabolism ; DNA Methylation ; Deoxycytidine/metabolism ; Isotope Labeling ; Mice ; Mice, Transgenic ; Oxidation-Reduction ; Pluripotent Stem Cells/cytology
Czasopismo naukowe
Tytuł :
Quantitative LC-MS Provides No Evidence for m dC in the Genome of Mouse Embryonic Stem Cells and Tissues.
Autorzy :
Schiffers S; Center for Integrated Protein Science (CiPSM) at the Department of Chemistry, LMU München, Butenandtstr. 5-13, 81377, München, Germany.
Ebert C; Center for Integrated Protein Science (CiPSM) at the Department of Chemistry, LMU München, Butenandtstr. 5-13, 81377, München, Germany.
Rahimoff R; Center for Integrated Protein Science (CiPSM) at the Department of Chemistry, LMU München, Butenandtstr. 5-13, 81377, München, Germany.
Kosmatchev O; Center for Integrated Protein Science (CiPSM) at the Department of Chemistry, LMU München, Butenandtstr. 5-13, 81377, München, Germany.
Steinbacher J; Center for Integrated Protein Science (CiPSM) at the Department of Chemistry, LMU München, Butenandtstr. 5-13, 81377, München, Germany.
Bohne AV; Biocenter of the LMU, Dept. Biologie 1 - Botanik, Molekulare Pflanzenwissenschaften, Grosshaderner Strasse 2-4, 82152, Planegg-Martinsried, Germany.
Spada F; Center for Integrated Protein Science (CiPSM) at the Department of Chemistry, LMU München, Butenandtstr. 5-13, 81377, München, Germany.
Michalakis S; CiPSM, Department of Pharmacy, LMU München, Pharmacology for Life Sciences, Butenandtstr. 7, 81377, München, Germany.
Nickelsen J; Biocenter of the LMU, Dept. Biologie 1 - Botanik, Molekulare Pflanzenwissenschaften, Grosshaderner Strasse 2-4, 82152, Planegg-Martinsried, Germany.
Müller M; Center for Integrated Protein Science (CiPSM) at the Department of Chemistry, LMU München, Butenandtstr. 5-13, 81377, München, Germany.
Carell T; Center for Integrated Protein Science (CiPSM) at the Department of Chemistry, LMU München, Butenandtstr. 5-13, 81377, München, Germany.
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Źródło :
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2017 Sep 04; Vol. 56 (37), pp. 11268-11271. Date of Electronic Publication: 2017 Mar 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genome*
Brain/*metabolism
Chromatography, High Pressure Liquid/*methods
Cytidine/*analogs & derivatives
Cytidine/*metabolism
Liver/*metabolism
Mass Spectrometry/*methods
Mouse Embryonic Stem Cells/*metabolism
Animals ; Chlamydomonas reinhardtii/genetics ; DNA/genetics ; Epigenesis, Genetic ; Limit of Detection ; Mice ; Synechocystis/genetics
Czasopismo naukowe
    Wyświetlanie 1-8 z 8

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