Autor: "Rajab IM" - OpacWWW

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Tytuł:: Monomeric C-reactive protein via endothelial CD31 for neurovascular inflammation in an ApoE genotype-dependent pattern: A risk factor for Alzheimer's disease?
Autorzy:: Zhang Z; Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts, USA.
Na H; Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts, USA.
Gan Q; Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts, USA.
Tao Q; Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts, USA.
Alekseyev Y; Microarray and Sequencing Core Facility, Boston University School of Medicine, Boston, Massachusetts, USA.
Hu J; Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA.
Yan Z; Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts, USA.
Yang JB; Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts, USA.
Tian H; Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts, USA.; Department of Pharmacology, Xiaman Medical College, Xiaman, China.
Zhu S; Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts, USA.
Li Q; Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts, USA.; Nursing School, Qiqihar Medical University, Qiqihar, China.
Rajab IM; Roosevelt University College of Pharmacy, Schaumburg, Illinois, USA.
Blusztajn JK; Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, Massachusetts, USA.
Wolozin B; Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts, USA.
Emili A; Department of Biochemistry, Boston University School of Medicine, Boston, Massachusetts, USA.
Zhang X; Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA.
Stein T; Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, Massachusetts, USA.; Alzheimer's Disease Center, Boston University School of Medicine, Boston, Massachusetts, USA.; VA Boston Healthcare System, Boston, Massachusetts, USA.; Department of Veterans Affairs Medical Center, Bedford, Massachusetts, USA.
Potempa LA; Roosevelt University College of Pharmacy, Schaumburg, Illinois, USA.
Qiu WQ; Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts, USA.; Alzheimer's Disease Center, Boston University School of Medicine, Boston, Massachusetts, USA.; Department of Psychiatry, Boston University School of Medicine, Boston, Massachusetts, USA.; Pokaż więcej
Źródło:: Aging cell [Aging Cell] 2021 Nov; Vol. 20 (11), pp. e13501. Date of Electronic Publication: 2021 Oct 23.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Genotype*
Alzheimer Disease/*metabolism
Apolipoproteins E/*metabolism
C-Reactive Protein/*metabolism
Endothelial Cells/*metabolism
Platelet Endothelial Cell Adhesion Molecule-1/*metabolism
Signal Transduction/*genetics
Adult ; Aged ; Aged, 80 and over ; Alzheimer Disease/genetics ; Alzheimer Disease/pathology ; Animals ; Apolipoprotein E4/metabolism ; Apolipoproteins E/genetics ; Brain/metabolism ; C-Reactive Protein/administration & dosage ; Case-Control Studies ; Cells, Cultured ; Female ; Gene Knock-In Techniques ; Gene Knockdown Techniques ; Humans ; Inflammation/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout, ApoE ; Middle Aged ; Oxidative Phosphorylation/drug effects ; Platelet Endothelial Cell Adhesion Molecule-1/genetics ; Risk Factors ; Signal Transduction/drug effects

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