Autor: "Rajesh Kumar, M." - OpacWWW

Skocz do pozycji: 1.

Tytuł:: N-substituted hydroxynaphthalene imino-oxindole derivatives as new class of PI3-kinase inhibitor and breast cancer drug: Molecular validation and structure-activity relationship studies.
Autorzy:: Rajesh Kumar M; Department of Chemistry, Bishop Heber College, Tiruchirappalli, India.
Alagumuthu M; Department of Biotechnology, School of Bio-Sciences and Technology, VIT University, Vellore, India.
Violet Dhayabaran V; Department of Chemistry, Bishop Heber College, Tiruchirappalli, India.; Pokaż więcej
Źródło:: Chemical biology & drug design [Chem Biol Drug Des] 2018 Jan; Vol. 91 (1), pp. 277-284. Date of Electronic Publication: 2017 Sep 04.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Phosphoinositide-3 Kinase Inhibitors*
Indoles/*chemistry
Protein Kinase Inhibitors/*chemistry
Binding Sites ; Breast Neoplasms/metabolism ; Breast Neoplasms/pathology ; Catalytic Domain ; Drug Design ; Female ; Humans ; Imines/chemistry ; Indoles/chemical synthesis ; Indoles/metabolism ; Inhibitory Concentration 50 ; MCF-7 Cells ; Molecular Docking Simulation ; Phosphatidylinositol 3-Kinases/metabolism ; Protein Kinase Inhibitors/chemical synthesis ; Protein Kinase Inhibitors/metabolism ; Structure-Activity Relationship

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