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Wyszukujesz frazę ""Rammes, Gerhard"" wg kryterium: Autor


Tytuł :
Two conformationally distinct α-synuclein oligomers share common epitopes and the ability to impair long-term potentiation.
Autorzy :
van Diggelen F; Interdisciplinary Nanoscience Center (iNANO), Aarhus University, Aarhus C, Denmark.; Crossbeta Biosciences BV, Utrecht, The Netherlands.
Hrle D; Klinik für Anaesthesiologie der Technischen Universität München, Klinikum Rechts der Isar, Munich, Germany.
Apetri M; Crossbeta Biosciences BV, Utrecht, The Netherlands.
Christiansen G; Department of Biomedicine, Aarhus University, Aarhus C, Denmark.
Rammes G; Klinik für Anaesthesiologie der Technischen Universität München, Klinikum Rechts der Isar, Munich, Germany.
Tepper A; Crossbeta Biosciences BV, Utrecht, The Netherlands.
Otzen DE; Interdisciplinary Nanoscience Center (iNANO), Aarhus University, Aarhus C, Denmark.
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Źródło :
PloS one [PLoS One] 2019 Mar 22; Vol. 14 (3), pp. e0213663. Date of Electronic Publication: 2019 Mar 22 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Epitopes/*chemistry
Long-Term Potentiation/*drug effects
Parkinson Disease/*physiopathology
alpha-Synuclein/*chemistry
Aldehydes/chemistry ; Animals ; Circular Dichroism ; Docosahexaenoic Acids/chemistry ; Fatty Acids, Unsaturated/chemistry ; Fluoresceins/chemistry ; Glutamine/chemistry ; Hippocampus/chemistry ; Humans ; Light ; Lipid Peroxidation ; Male ; Mice ; Mice, Inbred C57BL ; Microscopy, Atomic Force ; Neurons/chemistry ; Parkinson Disease/drug therapy ; Protein Binding ; Protein Structure, Secondary ; Rats ; Scattering, Radiation ; Spectroscopy, Fourier Transform Infrared ; Synapses
Czasopismo naukowe
Tytuł :
The NMDA receptor antagonist Radiprodil reverses the synaptotoxic effects of different amyloid-beta (Aβ) species on long-term potentiation (LTP).
Autorzy :
Rammes G; Department of Anaesthesiology, Technische Universität München, Munich, Germany. Electronic address: g.rammes@tum.de.
Seeser F; Department of Anaesthesiology, Technische Universität München, Munich, Germany.
Mattusch K; Department of Anaesthesiology, Technische Universität München, Munich, Germany.
Zhu K; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
Haas L; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
Kummer M; Clinical Neuroscience Unit, Dept. of Neurology, University of Bonn, Germany.
Heneka M; Clinical Neuroscience Unit, Dept. of Neurology, University of Bonn, Germany.
Herms J; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany.
Parsons CG; Non-Clinical Science, Merz Pharmaceuticals GmbH, Frankfurt am Main, Germany.
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Źródło :
Neuropharmacology [Neuropharmacology] 2018 Sep 15; Vol. 140, pp. 184-192. Date of Electronic Publication: 2018 Aug 11.
Typ publikacji :
Journal Article
MeSH Terms :
Acetamides/*pharmacology
Amyloid beta-Peptides/*antagonists & inhibitors
Excitatory Postsynaptic Potentials/*drug effects
Long-Term Potentiation/*drug effects
Peptide Fragments/*antagonists & inhibitors
Piperidines/*pharmacology
Amyloid beta-Peptides/toxicity ; Animals ; Dendritic Spines/drug effects ; Dose-Response Relationship, Drug ; Hippocampus/physiology ; Mice ; Peptide Fragments/adverse effects ; Peptide Fragments/toxicity
Czasopismo naukowe
Tytuł :
Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibition Impairs Synaptic Plasticity via Seizure Protein 6.
Autorzy :
Zhu K; German Center for Neurodegenerative Diseases, Munich, Germany; Center for Neuropathology and Prion Research, Munich, Germany; Munich Cluster for Systems Neurology, Munich, Germany.
Xiang X; Graduate School of Systemic Neuroscience, Ludwig-Maximilians University Munich, Munich, Germany.
Filser S; German Center for Neurodegenerative Diseases, Munich, Germany; Center for Neuropathology and Prion Research, Munich, Germany; Munich Cluster for Systems Neurology, Munich, Germany.
Marinković P; German Center for Neurodegenerative Diseases, Munich, Germany; German Center for Neurodegenerative Diseases, Munich, Germany.
Dorostkar MM; German Center for Neurodegenerative Diseases, Munich, Germany; Center for Neuropathology and Prion Research, Munich, Germany; Munich Cluster for Systems Neurology, Munich, Germany.
Crux S; German Center for Neurodegenerative Diseases, Munich, Germany; Center for Neuropathology and Prion Research, Munich, Germany; Munich Cluster for Systems Neurology, Munich, Germany.
Neumann U; Neuroscience, Novartis Institutes for BioMedical Research (NIBR), Basel, Switzerland.
Shimshek DR; Neuroscience, Novartis Institutes for BioMedical Research (NIBR), Basel, Switzerland.
Rammes G; Department of Anesthesiology, Klinikum rechts der Isar, Munich, Germany.
Haass C; German Center for Neurodegenerative Diseases, Munich, Germany; Biomedical Center, Biochemistry, Munich, Germany; Munich Cluster for Systems Neurology, Munich, Germany.
Lichtenthaler SF; German Center for Neurodegenerative Diseases, Munich, Germany; Munich Cluster for Systems Neurology, Munich, Germany; Institute for Advanced Study, Technical University of Munich, Munich, Germany; Neuroproteomics, Klinikum rechts der Isar, Munich, Germany.
Gunnersen JM; Department of Anatomy and Neuroscience, University of Melbourne, Melbourne, Victoria, Australia.
Herms J; German Center for Neurodegenerative Diseases, Munich, Germany; Center for Neuropathology and Prion Research, Munich, Germany; Munich Cluster for Systems Neurology, Munich, Germany. Electronic address: .
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Źródło :
Biological psychiatry [Biol Psychiatry] 2018 Mar 01; Vol. 83 (5), pp. 428-437. Date of Electronic Publication: 2016 Dec 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Amyloid Precursor Protein Secretases/*metabolism
Aspartic Acid Endopeptidases/*metabolism
Dendritic Spines/*metabolism
Hippocampus/*metabolism
Long-Term Potentiation/*physiology
Nerve Tissue Proteins/*metabolism
Neuronal Plasticity/*physiology
Amyloid Precursor Protein Secretases/antagonists & inhibitors ; Animals ; Aspartic Acid Endopeptidases/antagonists & inhibitors ; Mice, Inbred C57BL ; Mice, Knockout ; Mice, Transgenic
Czasopismo naukowe
Tytuł :
Desipramine targets astrocytes to attenuate synaptic plasticity via modulation of the ephrinA3/EphA4 signalling.
Autorzy :
Tanasic S; Max Planck Institute of Psychiatry, 80804 Munich, Germany.
Mattusch C; Max Planck Institute of Psychiatry, 80804 Munich, Germany; Department of Anesthesiology, Technische University, 81675 Munich, Germany.
Wagner EM; Max Planck Institute of Psychiatry, 80804 Munich, Germany.
Eder M; Max Planck Institute of Psychiatry, 80804 Munich, Germany.
Rupprecht R; Max Planck Institute of Psychiatry, 80804 Munich, Germany; Department of Psychiatry and Psychotherapy, University of Regensburg, 93053 Regensburg, Germany.
Rammes G; Max Planck Institute of Psychiatry, 80804 Munich, Germany; Department of Anesthesiology, Technische University, 81675 Munich, Germany.
Di Benedetto B; Max Planck Institute of Psychiatry, 80804 Munich, Germany; Department of Psychiatry and Psychotherapy, University of Regensburg, 93053 Regensburg, Germany. Electronic address: .
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Źródło :
Neuropharmacology [Neuropharmacology] 2016 Jun; Vol. 105, pp. 154-163. Date of Electronic Publication: 2016 Jan 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
MAP Kinase Signaling System*
Antidepressive Agents, Tricyclic/*administration & dosage
Astrocytes/*drug effects
Astrocytes/*metabolism
Desipramine/*administration & dosage
Ephrin-A3/*metabolism
Long-Term Potentiation/*drug effects
Receptor, EphA4/*metabolism
Animals ; CA1 Region, Hippocampal/drug effects ; CA1 Region, Hippocampal/metabolism ; Male ; Mice ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł :
MRZ-99030 - A novel modulator of Aβ aggregation: II - Reversal of Aβ oligomer-induced deficits in long-term potentiation (LTP) and cognitive performance in rats and mice.
Autorzy :
Rammes G; Department of Anaesthesiology, Technische Universität München, D-81675, Germany.
Gravius A; Merz Pharmaceuticals GmbH, Eckenheimer Landstrasse 100, D-60318, Frankfurt, Germany.
Ruitenberg M; Merz Pharmaceuticals GmbH, Eckenheimer Landstrasse 100, D-60318, Frankfurt, Germany.
Wegener N; Merz Pharmaceuticals GmbH, Eckenheimer Landstrasse 100, D-60318, Frankfurt, Germany.
Chambon C; Merz Pharmaceuticals GmbH, Eckenheimer Landstrasse 100, D-60318, Frankfurt, Germany.
Sroka-Saidi K; Merz Pharmaceuticals GmbH, Eckenheimer Landstrasse 100, D-60318, Frankfurt, Germany.
Jeggo R; Neurosolutions Ltd., P.O. Box 3517, Coventry, CV4 7ZS, UK.
Staniaszek L; Neurosolutions Ltd., P.O. Box 3517, Coventry, CV4 7ZS, UK.
Spanswick D; Neurosolutions Ltd., P.O. Box 3517, Coventry, CV4 7ZS, UK; Monash University, Department of Physiology, Clayton, Victoria, Australia; Universisty of Warwick Medical School, Coventry, CV4 7AL, UK.
O'Hare E; School of Psychology, Queens University, Belfast, BT7 1NN, UK.
Palmer P; School of Psychology, Queens University, Belfast, BT7 1NN, UK.
Kim EM; School of Psychology, University of Ulster, Coleraine, BT52 1SA, UK.
Bywalez W; Neurobiology, Biocenter, Ludwig-Maximilians-Universität München, D-82152, Germany.
Egger V; Neurobiology, Biocenter, Ludwig-Maximilians-Universität München, D-82152, Germany; Neurophysiology, Universität Regensburg, D-93040, Germany.
Parsons CG; Merz Pharmaceuticals GmbH, Eckenheimer Landstrasse 100, D-60318, Frankfurt, Germany. Electronic address: .
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Źródło :
Neuropharmacology [Neuropharmacology] 2015 May; Vol. 92, pp. 170-82. Date of Electronic Publication: 2015 Jan 28.
Typ publikacji :
Journal Article
MeSH Terms :
Cognition Disorders*/chemically induced
Cognition Disorders*/drug therapy
Cognition Disorders*/metabolism
Amyloid beta-Peptides/*metabolism
Amyloid beta-Peptides/*toxicity
Dipeptides/*pharmacology
Dipeptides/*therapeutic use
Long-Term Potentiation/*drug effects
Peptide Fragments/*metabolism
Peptide Fragments/*toxicity
Animals ; Calcium/metabolism ; Conditioning, Operant/drug effects ; Culture Media, Conditioned/pharmacology ; Disease Models, Animal ; Hippocampus/cytology ; Hippocampus/drug effects ; Hippocampus/physiology ; In Vitro Techniques ; Injections, Intraventricular ; Inositol/pharmacology ; Male ; Mice ; Mice, Inbred C57BL ; Neurons/drug effects ; Putamen/drug effects ; Putamen/metabolism ; Rats ; Rats, Sprague-Dawley ; Recognition, Psychology/drug effects
Czasopismo naukowe
Tytuł :
Sevoflurane anesthesia improves cognitive performance in mice, but does not influence in vitro long-term potentation in hippocampus CA1 stratum radiatum.
Autorzy :
Haseneder R; Department of Anesthesiology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany. />Starker L
Berkmann J
Kellermann K
Jungwirth B
Blobner M
Eder M
Kochs E
Rammes G
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Źródło :
PloS one [PLoS One] 2013 May 28; Vol. 8 (5), pp. e64732. Date of Electronic Publication: 2013 May 28 (Print Publication: 2013).
Typ publikacji :
Journal Article
MeSH Terms :
Anesthesia*
CA1 Region, Hippocampal/*drug effects
CA1 Region, Hippocampal/*physiology
Cognition/*drug effects
Long-Term Potentiation/*drug effects
Methyl Ethers/*pharmacology
Animals ; Male ; Methyl Ethers/administration & dosage ; Mice ; Mice, Inbred C57BL ; Protein Subunits/metabolism ; Receptors, N-Methyl-D-Aspartate/metabolism ; Sevoflurane ; Up-Regulation/drug effects
Czasopismo naukowe
Tytuł :
Xenon attenuates hippocampal long-term potentiation by diminishing synaptic and extrasynaptic N-methyl-D-aspartate receptor currents.
Autorzy :
Kratzer S; Department of Anesthesiology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany. />Mattusch C
Kochs E
Eder M
Haseneder R
Rammes G
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Źródło :
Anesthesiology [Anesthesiology] 2012 Mar; Vol. 116 (3), pp. 673-82.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Hippocampus/*physiology
Long-Term Potentiation/*physiology
Receptors, N-Methyl-D-Aspartate/*antagonists & inhibitors
Synapses/*physiology
Xenon/*pharmacology
Animals ; Excitatory Postsynaptic Potentials/drug effects ; Excitatory Postsynaptic Potentials/physiology ; Hippocampus/drug effects ; Long-Term Potentiation/drug effects ; Male ; Mice ; Mice, Inbred C57BL ; Neural Inhibition/drug effects ; Neural Inhibition/physiology ; Organ Culture Techniques ; Receptors, N-Methyl-D-Aspartate/physiology ; Synapses/drug effects
Czasopismo naukowe
Tytuł :
Therapeutic significance of NR2B-containing NMDA receptors and mGluR5 metabotropic glutamate receptors in mediating the synaptotoxic effects of β-amyloid oligomers on long-term potentiation (LTP) in murine hippocampal slices.
Autorzy :
Rammes G; Dept. of Anesthesiology, Technische Universität München, D-81675 Munich, Germany.
Hasenjäger A
Sroka-Saidi K
Deussing JM
Parsons CG
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Źródło :
Neuropharmacology [Neuropharmacology] 2011 May; Vol. 60 (6), pp. 982-90. Date of Electronic Publication: 2011 Feb 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Amyloid beta-Peptides/*toxicity
Hippocampus/*drug effects
Hippocampus/*physiology
Long-Term Potentiation/*physiology
Peptide Fragments/*toxicity
Receptors, Metabotropic Glutamate/*physiology
Receptors, N-Methyl-D-Aspartate/*physiology
Amyloid beta-Peptides/antagonists & inhibitors ; Amyloid beta-Peptides/chemical synthesis ; Amyloid beta-Peptides/metabolism ; Animals ; Electric Stimulation/methods ; Excitatory Postsynaptic Potentials/drug effects ; Excitatory Postsynaptic Potentials/physiology ; Hippocampus/metabolism ; In Vitro Techniques ; Long-Term Potentiation/drug effects ; Male ; Memantine/pharmacology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Peptide Fragments/antagonists & inhibitors ; Peptide Fragments/chemical synthesis ; Peptide Fragments/metabolism ; Phenols/pharmacology ; Piperidines/pharmacology ; Pyridines/pharmacology ; Receptor, Metabotropic Glutamate 5 ; Receptors, Metabotropic Glutamate/antagonists & inhibitors ; Receptors, N-Methyl-D-Aspartate/antagonists & inhibitors ; Receptors, N-Methyl-D-Aspartate/genetics ; Synapses/metabolism ; Synapses/physiology
Czasopismo naukowe
Tytuł :
Isoflurane and sevoflurane dose-dependently impair hippocampal long-term potentiation.
Autorzy :
Haseneder R; Department of Anaesthesiology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Strasse 22, 81675 Munich, Germany. />Kratzer S
von Meyer L
Eder M
Kochs E
Rammes G
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Źródło :
European journal of pharmacology [Eur J Pharmacol] 2009 Nov 25; Vol. 623 (1-3), pp. 47-51. Date of Electronic Publication: 2009 Sep 16.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Anesthetics, Inhalation/*pharmacology
Hippocampus/*drug effects
Isoflurane/*pharmacology
Long-Term Potentiation/*drug effects
Methyl Ethers/*pharmacology
Synapses/*drug effects
Synaptic Transmission/*drug effects
Animals ; CA1 Region, Hippocampal/drug effects ; Dose-Response Relationship, Drug ; Electric Stimulation ; Excitatory Postsynaptic Potentials/drug effects ; Hippocampus/physiology ; In Vitro Techniques ; Isoflurane/analysis ; Male ; Methyl Ethers/analysis ; Mice ; Sevoflurane ; Synapses/physiology
Czasopismo naukowe
Tytuł :
Isoflurane anaesthesia reversibly improves cognitive function and long-term potentiation (LTP) via an up-regulation in NMDA receptor 2B subunit expression.
Autorzy :
Rammes G; Department of Anaesthesiology, Technische Universität München, D-81675 Munich, Germany. rammes@mpipsykl.mpg.de
Starker LK
Haseneder R
Berkmann J
Plack A
Zieglgänsberger W
Ohl F
Kochs EF
Blobner M
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Źródło :
Neuropharmacology [Neuropharmacology] 2009 Mar; Vol. 56 (3), pp. 626-36. Date of Electronic Publication: 2008 Nov 27.
Typ publikacji :
Journal Article
MeSH Terms :
Up-Regulation*
Anesthetics, Inhalation/*pharmacology
Cognition/*drug effects
Isoflurane/*pharmacology
Long-Term Potentiation/*drug effects
Receptors, N-Methyl-D-Aspartate/*metabolism
Animals ; Hippocampus/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Receptors, N-Methyl-D-Aspartate/antagonists & inhibitors
Czasopismo naukowe
Tytuł :
Activation of kappa opioid receptors decreases synaptic transmission and inhibits long-term potentiation in the basolateral amygdala of the mouse.
Autorzy :
Huge V; Clinical Neuropharmacology Group, Max-Planck-Institut für Psychiatrie, Kraepelinstrasse 2-10, 80804 Munich, Germany. />Rammes G
Beyer A
Zieglgänsberger W
Azad SC
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Źródło :
European journal of pain (London, England) [Eur J Pain] 2009 Feb; Vol. 13 (2), pp. 124-9. Date of Electronic Publication: 2008 Apr 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Amygdala/*physiology
Long-Term Potentiation/*drug effects
Pain/*psychology
Receptors, Opioid, kappa/*agonists
Synaptic Transmission/*drug effects
3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer/pharmacology ; Amygdala/drug effects ; Analgesics, Non-Narcotic/pharmacology ; Animals ; Chronic Disease ; Electric Stimulation ; Electrophysiology ; Emotions/physiology ; Extinction, Psychological/drug effects ; Male ; Mice ; Mice, Inbred C57BL ; Naltrexone/analogs & derivatives ; Naltrexone/pharmacology ; Pain/physiopathology
Czasopismo naukowe
Tytuł :
Reduced anxiety, conditioned fear, and hippocampal long-term potentiation in transient receptor potential vanilloid type 1 receptor-deficient mice.
Autorzy :
Marsch R; Max Planck Institute of Psychiatry, D-80804 Munich, Germany.
Foeller E
Rammes G
Bunck M
Kössl M
Holsboer F
Zieglgänsberger W
Landgraf R
Lutz B
Wotjak CT
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Źródło :
The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2007 Jan 24; Vol. 27 (4), pp. 832-9.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anxiety/*physiopathology
Conditioning, Psychological/*physiology
Fear/*physiology
Hippocampus/*physiology
Long-Term Potentiation/*physiology
TRPV Cation Channels/*physiology
Animals ; Anxiety/genetics ; Anxiety/psychology ; Fear/psychology ; Long-Term Potentiation/genetics ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Neuronal Plasticity/genetics ; Neuronal Plasticity/physiology ; Synaptic Transmission/genetics ; Synaptic Transmission/physiology ; TRPV Cation Channels/deficiency ; TRPV Cation Channels/genetics
Czasopismo naukowe
Tytuł :
The Aβ aggregation modulator MRZ-99030 prevents and even reverses synaptotoxic effects of Aβ1-42 on LTP even following serial dilution to a 500:1 stoichiometric excess of Aβ1-42, suggesting a beneficial prion-like seeding mechanism.
Autorzy :
Rammes, Gerhard (AUTHOR)
Parsons, Chris G. (AUTHOR)
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Źródło :
Neuropharmacology. Nov2020, Vol. 179, pN.PAG-N.PAG. 1p.
Czasopismo naukowe

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