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Tytuł :
Targeting integrins with RGD-conjugated gold nanoparticles in radiotherapy decreases the invasive activity of breast cancer cells
Autorzy :
Wu PH
Onodera Y
Ichikawa Y
Rankin EB
Giaccia AJ
Watanabe Y
Qian W
Hashimoto T
Shirato H
Nam JM
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Temat :
gold nanoparticles
radiotherapy
breast cancer
invasion
integrin
fibronectin
Medicine (General)
R5-920
Źródło :
International Journal of Nanomedicine, Vol Volume 12, Pp 5069-5085 (2017)
Opis pliku :
electronic resource
Relacje :
https://www.dovepress.com/targeting-integrins-with-rgd-conjugated-gold-nanoparticles-in-radiothe-peer-reviewed-article-IJN; https://doaj.org/toc/1178-2013
Dostęp URL :
https://doaj.org/article/7fd4df3235b342629994a93a747c4311
Czasopismo naukowe
Tytuł :
Abdominal FLASH irradiation reduces radiation-induced gastrointestinal toxicity for the treatment of ovarian cancer in mice.
Autorzy :
Levy K; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, 94305, USA.; Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Natarajan S; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Wang J; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Chow S; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, 94305, USA.; Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Eggold JT; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Loo PE; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Manjappa R; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Melemenidis S; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Lartey FM; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Schüler E; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Skinner L; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Rafat M; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, 94305, USA.; Department of Chemical and Biomolecular Engineering, Vanderbilt University School of Engineering, Nashville, TN, 37235, USA.
Ko R; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Kim A; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, 94305, USA.
H Al-Rawi D; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, 94305, USA.
von Eyben R; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Dorigo O; Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Casey KM; Department of Comparative Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Graves EE; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, 94305, USA.; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Bush K; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Yu AS; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Koong AC; Division of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Maxim PG; Department of Radiation Oncology, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
Loo BW Jr; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, 94305, USA. .; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, 94305, USA. .
Rankin EB; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, 94305, USA. .; Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, CA, 94305, USA. .; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, 94305, USA. .
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Źródło :
Scientific reports [Sci Rep] 2020 Dec 10; Vol. 10 (1), pp. 21600. Date of Electronic Publication: 2020 Dec 10.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't
Czasopismo naukowe
Tytuł :
Omental macrophages secrete chemokine ligands that promote ovarian cancer colonization of the omentum via CCR1.
Autorzy :
Krishnan V; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Stanford School of Medicine, Stanford Cancer Institute, Stanford, CA, USA.
Tallapragada S; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Stanford School of Medicine, Stanford Cancer Institute, Stanford, CA, USA.
Schaar B; Genome Technology Center, Stanford, CA, USA.
Kamat K; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Stanford School of Medicine, Stanford Cancer Institute, Stanford, CA, USA.
Chanana AM; Department of Obstetrics and Gynecology, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
Zhang Y; Department of Physiology and Chemistry, Genentech, San Francisco, CA, USA.
Patel S; Department of Thoracic Head and Neck Medical Oncology, Division of Cancer Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA.
Parkash V; Department of Pathology, Yale School of Medicine and Yale School of Public Health, New Haven, CT, USA.
Rinker-Schaeffer C; Department of Surgery, Division of Urology, University of Chicago, Chicago, IL, USA.
Folkins AK; Department of Pathology, Stanford School of Medicine, Stanford, CA, USA.
Rankin EB; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Stanford School of Medicine, Stanford Cancer Institute, Stanford, CA, USA.; Department of Radiation Oncology, Stanford School of Medicine, Stanford, CA, USA.
Dorigo O; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Stanford School of Medicine, Stanford Cancer Institute, Stanford, CA, USA. .; Stanford Women's Cancer Center, Stanford, CA, USA. .
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Źródło :
Communications biology [Commun Biol] 2020 Sep 22; Vol. 3 (1), pp. 524. Date of Electronic Publication: 2020 Sep 22.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
The m A RNA demethylase FTO is a HIF-independent synthetic lethal partner with the VHL tumor suppressor.
Autorzy :
Xiao Y; Department of Radiation Oncology, Stanford University, Stanford, CA 94305.
Thakkar KN; Department of Radiation Oncology, Stanford University, Stanford, CA 94305.
Zhao H; Department of Urology, Stanford University, Stanford, CA 94305.
Broughton J; Mammoth Biosciences, South San Francisco, CA 94080.
Li Y; Department of Radiation Oncology, Stanford University, Stanford, CA 94305.
Seoane JA; Department of Medicine, Stanford University, Stanford, CA 94305.; Deparment of Genetics, Stanford University, Stanford, CA 94305.
Diep AN; Department of Radiation Oncology, Stanford University, Stanford, CA 94305.
Metzner TJ; Department of Urology, Stanford University, Stanford, CA 94305.
von Eyben R; Department of Radiation Oncology, Stanford University, Stanford, CA 94305.
Dill DL; Department of Computer Science, Stanford University, Stanford, CA 94305.
Brooks JD; Department of Urology, Stanford University, Stanford, CA 94305.
Curtis C; Department of Medicine, Stanford University, Stanford, CA 94305.; Deparment of Genetics, Stanford University, Stanford, CA 94305.
Leppert JT; Department of Urology, Stanford University, Stanford, CA 94305.
Ye J; Department of Radiation Oncology, Stanford University, Stanford, CA 94305.
Peehl DM; Deparment of Genetics, Stanford University, Stanford, CA 94305.; Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94158.
Giaccia AJ; Department of Radiation Oncology, Stanford University, Stanford, CA 94305.
Sinha S; Department of Computer Science, Stanford University, Stanford, CA 94305.
Rankin EB; Department of Radiation Oncology, Stanford University, Stanford, CA 94305; .; Department of Obstetrics and Gynecology, Stanford University, Stanford, CA 94305.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Sep 01; Vol. 117 (35), pp. 21441-21449. Date of Electronic Publication: 2020 Aug 19.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Synthetic Lethal Mutations*
Alpha-Ketoglutarate-Dependent Dioxygenase FTO/*genetics
Carcinoma, Renal Cell/*genetics
Kidney Neoplasms/*genetics
Von Hippel-Lindau Tumor Suppressor Protein/*genetics
Alpha-Ketoglutarate-Dependent Dioxygenase FTO/metabolism ; Amino Acid Transport System ASC/metabolism ; Animals ; Basic Helix-Loop-Helix Transcription Factors/metabolism ; Carcinoma, Renal Cell/metabolism ; Cell Line, Tumor ; Computer Simulation ; Humans ; Hypoxia-Inducible Factor 1/metabolism ; Kidney Neoplasms/metabolism ; Mice, Knockout ; Minor Histocompatibility Antigens/metabolism
Czasopismo naukowe
Tytuł :
Evaluating the Reproducibility of Mouse Anatomy under Rotation in a Custom Immobilization Device for Conformal FLASH Radiotherapy.
Autorzy :
Ko RB; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California.
Soto LA; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California.
von Eyben R; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California.
Melemenidis S; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California.
Rankin EB; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California.; Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, California.; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, California.
Maxim PG; Department of Radiation Oncology, Indiana University School of Medicine, Indianapolis, Indiana.
Graves EE; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California.; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, California.
Loo BW; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California.; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, California.
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Źródło :
Radiation research [Radiat Res] 2020 Aug 28. Date of Electronic Publication: 2020 Aug 28.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Validated limited gene predictor for cervical cancer lymph node metastases.
Autorzy :
Bloomstein JD; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, USA.
von Eyben R; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, USA.
Chan A; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, USA.
Rankin EB; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, USA.
Fregoso DR; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, USA.
Wang-Chiang J; Department of Gynecologic Oncology, Santa Clara Valley Medical Center, Fruitdale, CA, USA.
Lee L; Department of Gynecologic Oncology, Santa Clara Valley Medical Center, Fruitdale, CA, USA.
Xie LX; Department of Radiation Oncology, Xiamen University Xiang'an Hospital, Xiamen, Fujian, China.
David SM; Department of Clinical Obstetrics & Gynecology, University of Illinois, Chicago, IL, USA.
Stehr H; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
Esfahani MS; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, USA.
Giaccia AJ; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, USA.
Kidd EA; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, USA.
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Źródło :
Oncotarget [Oncotarget] 2020 Jun 16; Vol. 11 (24), pp. 2302-2309. Date of Electronic Publication: 2020 Jun 16 (Print Publication: 2020).
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Induced Tumor Heterogeneity Reveals Factors Informing Radiation and Immunotherapy Combinations.
Autorzy :
Aguilera TA; Department of Radiation Oncology, Stanford University, Stanford, California. .; Department of Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, Texas.
Elghonaimy EA; Department of Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, Texas.
Shehade H; Department of Radiation Oncology, Stanford University, Stanford, California.
Rafat M; Department of Radiation Oncology, Stanford University, Stanford, California.; Department of Biomolecular Engineering, Vanderbilt University, Nashville, Tennessee.; Department of Radiation Oncology, Vanderbilt University Medical Center, Nashville, Tennessee.
Castellini L; Department of Radiation Oncology, Stanford University, Stanford, California.
Jiang D; Department of Radiation Oncology, Stanford University, Stanford, California.; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Kariolis M; Department of Radiation Oncology, Stanford University, Stanford, California.
Koong AC; Department of Radiation Oncology, Stanford University, Stanford, California.; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Le QT; Department of Radiation Oncology, Stanford University, Stanford, California.
Ellies LG; Department of Pathology, University of California San Diego, La Jolla, California.
Rankin EB; Department of Radiation Oncology, Stanford University, Stanford, California.
Graves EE; Department of Radiation Oncology, Stanford University, Stanford, California.
Giaccia AJ; Department of Radiation Oncology, Stanford University, Stanford, California. .
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Źródło :
Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2020 Jun 15; Vol. 26 (12), pp. 2972-2985. Date of Electronic Publication: 2020 Feb 25.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Czasopismo naukowe
Tytuł :
Metabolic Profiling Reveals a Dependency of Human Metastatic Breast Cancer on Mitochondrial Serine and One-Carbon Unit Metabolism.
Autorzy :
Li AM; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California.; Cancer Biology Program, Stanford University School of Medicine, Stanford, California.
Ducker GS; Lewis-Sigler Institute for Integrative Genomics and Department of Chemistry, Princeton University, Princeton, New Jersey.
Li Y; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California.
Seoane JA; Department of Medicine, Stanford University School of Medicine, Stanford, California.; Department of Genetics, Stanford University School of Medicine, Stanford, California.; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, California.
Xiao Y; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California.
Melemenidis S; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California.
Zhou Y; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California.
Liu L; Lewis-Sigler Institute for Integrative Genomics and Department of Chemistry, Princeton University, Princeton, New Jersey.
Vanharanta S; MRC Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Cambridge, UK.
Graves EE; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California.; Cancer Biology Program, Stanford University School of Medicine, Stanford, California.
Rankin EB; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California.; Cancer Biology Program, Stanford University School of Medicine, Stanford, California.; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, California.
Curtis C; Cancer Biology Program, Stanford University School of Medicine, Stanford, California.; Department of Medicine, Stanford University School of Medicine, Stanford, California.; Department of Genetics, Stanford University School of Medicine, Stanford, California.; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, California.
Massagué J; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York.
Rabinowitz JD; Lewis-Sigler Institute for Integrative Genomics and Department of Chemistry, Princeton University, Princeton, New Jersey.
Thompson CB; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York. .
Ye J; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California. .; Cancer Biology Program, Stanford University School of Medicine, Stanford, California.; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, California.
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Źródło :
Molecular cancer research : MCR [Mol Cancer Res] 2020 Apr; Vol. 18 (4), pp. 599-611. Date of Electronic Publication: 2020 Jan 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Czasopismo naukowe
Tytuł :
S100A10 Is a Critical Mediator of GAS6/AXL-Induced Angiogenesis in Renal Cell Carcinoma.
Autorzy :
Xiao Y; Department of Radiation Oncology, Stanford University, Palo Alto, California.
Zhao H; Department of Urology, Stanford University, Palo Alto, California.
Tian L; Department of Medicine, Division of Cardiology, Stanford University, Palo Alto, California.
Nolley R; Department of Urology, Stanford University, Palo Alto, California.
Diep AN; Department of Radiation Oncology, Stanford University, Palo Alto, California.
Ernst A; Department of Radiation Oncology, Stanford University, Palo Alto, California.
Fuh KC; Department of Obstetrics and Gynecology, Washington University, St. Louis, Missouri.
Miao YR; Department of Radiation Oncology, Stanford University, Palo Alto, California.
von Eyben R; Department of Radiation Oncology, Stanford University, Palo Alto, California.
Leppert JT; Department of Urology, Stanford University, Palo Alto, California.
Brooks JD; Department of Urology, Stanford University, Palo Alto, California.
Peehl DM; Department of Urology, Stanford University, Palo Alto, California.
Giaccia AJ; Department of Radiation Oncology, Stanford University, Palo Alto, California.
Rankin EB; Department of Radiation Oncology, Stanford University, Palo Alto, California. .; Department of Obstetrics and Gynecology, Stanford University, Palo Alto, California.
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Źródło :
Cancer research [Cancer Res] 2019 Nov 15; Vol. 79 (22), pp. 5758-5768. Date of Electronic Publication: 2019 Oct 04.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Annexin A2/*metabolism
Carcinoma, Renal Cell/*metabolism
Intercellular Signaling Peptides and Proteins/*metabolism
Kidney Neoplasms/*metabolism
Neovascularization, Pathologic/*metabolism
Proto-Oncogene Proteins/*metabolism
Receptor Protein-Tyrosine Kinases/*metabolism
S100 Proteins/*metabolism
Animals ; Carcinoma, Renal Cell/pathology ; Cell Line ; Cell Line, Tumor ; Endothelial Cells/metabolism ; Endothelial Cells/pathology ; Humans ; Kidney/metabolism ; Kidney/pathology ; Kidney Neoplasms/pathology ; Mice ; Mice, Knockout ; Neovascularization, Pathologic/pathology ; Signal Transduction/physiology
Czasopismo naukowe
Tytuł :
Genomics and molecular mechanisms of high grade serous ovarian cancer: the 12th Biennial Rivkin Center Ovarian Cancer Research Symposium.
Autorzy :
Rankin EB; Radiation Oncology and Obstetrics and Gynecology, Stanford University, Stanford, California, USA .
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Źródło :
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society [Int J Gynecol Cancer] 2019 Aug; Vol. 29 (Suppl 2), pp. s7-s11.
Typ publikacji :
Congress; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Cystadenocarcinoma, Serous/*genetics
Cystadenocarcinoma, Serous/*pathology
Ovarian Neoplasms/*genetics
Ovarian Neoplasms/*pathology
Animals ; Female ; Genomics ; Humans ; Neoplasm Grading
Raport
Tytuł :
Collagen Remodeling in the Hypoxic Tumor-Mesothelial Niche Promotes Ovarian Cancer Metastasis.
Autorzy :
Natarajan S; Department of Radiation Oncology, Stanford University, Palo Alto, California.
Foreman KM; Department of Radiation Oncology, Stanford University, Palo Alto, California.
Soriano MI; Department of Radiation Oncology, Stanford University, Palo Alto, California.
Rossen NS; Department of Radiation Oncology, Stanford University, Palo Alto, California.; Department of Materials Science and Engineering, Stanford University, Palo Alto, California.
Shehade H; Department of Radiation Oncology, Stanford University, Palo Alto, California.
Fregoso DR; Department of Radiation Oncology, Stanford University, Palo Alto, California.
Eggold JT; Department of Radiation Oncology, Stanford University, Palo Alto, California.
Krishnan V; Department of Obstetrics and Gynecology, Stanford University, Palo Alto, California.
Dorigo O; Department of Obstetrics and Gynecology, Stanford University, Palo Alto, California.
Krieg AJ; Oregon Health & Science University, Portland, Oregon.
Heilshorn SC; Department of Materials Science and Engineering, Stanford University, Palo Alto, California.
Sinha S; SRI International, Menlo Park, California.
Fuh KC; Division of Gynecologic Oncology, Washington University, St. Louis, Missouri.
Rankin EB; Department of Radiation Oncology, Stanford University, Palo Alto, California. .; Department of Obstetrics and Gynecology, Stanford University, Palo Alto, California.
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Źródło :
Cancer research [Cancer Res] 2019 May 01; Vol. 79 (9), pp. 2271-2284. Date of Electronic Publication: 2019 Mar 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Collagen/*metabolism
Cystadenocarcinoma, Serous/*secondary
Epithelium/*physiopathology
Extracellular Matrix/*metabolism
Hypoxia/*physiopathology
Ovarian Neoplasms/*pathology
Peritoneal Neoplasms/*secondary
Adult ; Aged ; Aged, 80 and over ; Animals ; Apoptosis ; Basic Helix-Loop-Helix Transcription Factors/genetics ; Basic Helix-Loop-Helix Transcription Factors/metabolism ; Cell Proliferation ; Cystadenocarcinoma, Serous/genetics ; Cystadenocarcinoma, Serous/metabolism ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Hypoxia-Inducible Factor 1, alpha Subunit/genetics ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Middle Aged ; Ovarian Neoplasms/genetics ; Ovarian Neoplasms/metabolism ; Peritoneal Neoplasms/genetics ; Peritoneal Neoplasms/metabolism ; Prognosis ; Protein-Lysine 6-Oxidase/genetics ; Protein-Lysine 6-Oxidase/metabolism ; Signal Transduction ; Tumor Cells, Cultured ; Tumor Microenvironment ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Erythropoiesis, EPO, macrophages, and bone.
Autorzy :
Eggold JT; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, USA; Cancer Biology Program, Stanford University School of Medicine, Stanford, CA, USA.
Rankin EB; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, USA; Cancer Biology Program, Stanford University School of Medicine, Stanford, CA, USA; Department of Obstetrics & Gynecologic Oncology, Stanford University School of Medicine, Stanford, CA, USA. Electronic address: .
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Źródło :
Bone [Bone] 2019 Feb; Vol. 119, pp. 36-41. Date of Electronic Publication: 2018 Mar 15.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Review
MeSH Terms :
Erythropoiesis*
Bone and Bones/*metabolism
Erythropoietin/*metabolism
Macrophages/*metabolism
Animals ; Homeostasis ; Humans ; Models, Biological
Czasopismo naukowe
Tytuł :
Hypoxia-Induced Phenotypes that Mediate Tumor Heterogeneity.
Autorzy :
Qian J; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, USA.
Rankin EB; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, USA. .; Department of Obstetrics & Gynecologic Oncology, Stanford University School of Medicine, Stanford, CA, USA. .
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Źródło :
Advances in experimental medicine and biology [Adv Exp Med Biol] 2019; Vol. 1136, pp. 43-55.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Tumor Hypoxia*
Neoplasms/*pathology
Neoplastic Stem Cells/*cytology
Basic Helix-Loop-Helix Transcription Factors ; Cell Hypoxia ; Cell Line, Tumor ; Drug Resistance, Neoplasm ; Humans ; Hypoxia-Inducible Factor 1, alpha Subunit ; Phenotype
Czasopismo naukowe
Tytuł :
Cabozantinib inhibits tumor growth and metastasis of a patient-derived xenograft model of papillary renal cell carcinoma with MET mutation.
Autorzy :
Zhao H; a Department of Urology , Stanford University School of Medicine , Stanford , CA , USA.
Nolley R; a Department of Urology , Stanford University School of Medicine , Stanford , CA , USA.
Chan AMW; b Department of Radiation Oncology , Stanford University School of Medicine , Stanford , CA , USA.
Rankin EB; b Department of Radiation Oncology , Stanford University School of Medicine , Stanford , CA , USA.
Peehl DM; a Department of Urology , Stanford University School of Medicine , Stanford , CA , USA.
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Źródło :
Cancer biology & therapy [Cancer Biol Ther] 2017 Nov 02; Vol. 18 (11), pp. 863-871. Date of Electronic Publication: 2016 Aug 11.
Typ publikacji :
Journal Article
MeSH Terms :
Anilides/*therapeutic use
Carcinoma, Renal Cell/*drug therapy
Kidney Neoplasms/*drug therapy
Pyridines/*therapeutic use
Receptor Protein-Tyrosine Kinases/*therapeutic use
Anilides/pharmacology ; Animals ; Carcinoma, Renal Cell/pathology ; Disease Models, Animal ; Humans ; Kidney Neoplasms/pathology ; Mice ; Mutation ; Neoplasm Metastasis ; Pyridines/pharmacology ; Receptor Protein-Tyrosine Kinases/pharmacology ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Systematic discovery of mutation-specific synthetic lethals by mining pan-cancer human primary tumor data.
Autorzy :
Sinha S; Department of Computer Science, Stanford University, Stanford, California 94305, USA.
Thomas D; Department of Medicine, Division of Hematology, Cancer Institute, and Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.
Chan S; Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada M5G 2M9.
Gao Y; Department of Electrical Engineering and Computer Science, University of California at Berkeley, Berkeley, California 94720, USA.
Brunen D; Division of Molecular Carcinogenesis, The Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam 1066 CX, The Netherlands.
Torabi D; Department of Medicine, Division of Hematology, Cancer Institute, and Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.
Reinisch A; Department of Medicine, Division of Hematology, Cancer Institute, and Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.
Hernandez D; Department of Medicine, Division of Hematology, Cancer Institute, and Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.
Chan A; Division of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305, USA.
Rankin EB; Division of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305, USA.; Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, California 94305, USA.
Bernards R; Division of Molecular Carcinogenesis, The Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam 1066 CX, The Netherlands.
Majeti R; Department of Medicine, Division of Hematology, Cancer Institute, and Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.
Dill DL; Department of Computer Science, Stanford University, Stanford, California 94305, USA.
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Źródło :
Nature communications [Nat Commun] 2017 May 31; Vol. 8, pp. 15580. Date of Electronic Publication: 2017 May 31.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Algorithms*
Computational Biology/*methods
Leukemia, Myeloid, Acute/*genetics
Synthetic Lethal Mutations/*genetics
Animals ; Cell Line, Tumor ; Female ; Humans ; MCF-7 Cells ; Male ; Mice ; Neoplasm Transplantation ; Precision Medicine/methods ; RNA Interference ; RNA, Small Interfering/genetics ; Transplantation, Heterologous
Czasopismo naukowe

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