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Wyszukujesz frazę ""Rats, Mutant Strains"" wg kryterium: Temat


Tytuł:
4-aminopyridine improves evoked potentials and ambulation in the taiep rat: A model of hypomyelination with atrophy of basal ganglia and cerebellum.
Autorzy:
Eguibar JR; Laboratorio de Neurofisiología de la Conducta y Control Motor, Instituto de Fisiología, Benemérita Universidad Autónoma de Puebla, Puebla, Pue, México.; Dirección General de Desarrollo Internacional, Benemérita Universidad Autónoma de Puebla, Puebla, Pue, México.
Cortes C; Laboratorio de Neurofisiología de la Conducta y Control Motor, Instituto de Fisiología, Benemérita Universidad Autónoma de Puebla, Puebla, Pue, México.
Hernandez VH; Departamento de Ingenierías Química, Electrónica y Biomédica, División de Ciencias e Ingenierías, Universidad de Guanajuato, León, Gto, México.
Lopez-Juarez A; Departamento de Ingenierías Química, Electrónica y Biomédica, División de Ciencias e Ingenierías, Universidad de Guanajuato, León, Gto, México.
Piazza V; Centro de Investigaciones en Óptica, A.C., León, Gto, México.
Carmona D; Departamento de Ingenierías Química, Electrónica y Biomédica, División de Ciencias e Ingenierías, Universidad de Guanajuato, León, Gto, México.; Centro de Investigaciones en Óptica, A.C., León, Gto, México.
Kleinert-Altamirano A; Centro de Rehabilitación Infantil Teletón, Chiapas, Chis, México.
Morales-Campos B; Departamento de Fisiología, Facultad de Medicina, Benemérita Universidad Autónoma de Puebla, Puebla, Puebla, Pue, México.
Salceda E; Revista Elementos, Benemérita Universidad Autónoma de Puebla, Puebla, Pue, México.
Roncagliolo M; Instituto de Fisiología, Facultad de Ciencias, Universidad de Valparaíso, Valparaíso, Chile.
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Źródło:
PloS one [PLoS One] 2024 Mar 01; Vol. 19 (3), pp. e0298208. Date of Electronic Publication: 2024 Mar 01 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Demyelinating Diseases*/drug therapy
Demyelinating Diseases*/genetics
White Matter*
Hereditary Central Nervous System Demyelinating Diseases*
Rats ; Humans ; Animals ; Rats, Mutant Strains ; 4-Aminopyridine/pharmacology ; Cerebellum ; Basal Ganglia ; Evoked Potentials ; Walking ; Atrophy
SCR Disease Name:
Leukodystrophy, Hypomyelinating, 6
Czasopismo naukowe
Tytuł:
Age-related behavioral, morphological and physiological changes in the hippocampus of zitter rats.
Autorzy:
Ehara A; Department of Histology and Neurobiology, Dokkyo Medical University School of Medicine, Mibu, Tochigi, 321-0293, Japan.
Maekawa M; Department of Physiology and Biological Information, Dokkyo Medical University School of Medicine, Mibu, Tochigi, Japan.
Hori Y; Department of Physiology and Biological Information, Dokkyo Medical University School of Medicine, Mibu, Tochigi, Japan.
Nakadate K; Department of Basic Biology, Educational and Research Center for Pharmacy, Meiji Pharmaceutical University, Kiyose, Tokyo, Japan.
Ueda S; Department of Histology and Neurobiology, Dokkyo Medical University School of Medicine, Mibu, Tochigi, 321-0293, Japan. .
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Źródło:
Anatomical science international [Anat Sci Int] 2018 Jun; Vol. 93 (3), pp. 332-339. Date of Electronic Publication: 2017 Sep 21.
Typ publikacji:
Journal Article
MeSH Terms:
Rats, Mutant Strains*
Aging/*pathology
Aging/*physiology
Hippocampus/*pathology
Hippocampus/*physiopathology
Seizures/*etiology
Animals ; Female ; Male ; Nerve Degeneration ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł:
The Quinpirole Hypolocomotive Effects are Strain and Route of Administration Dependent in SHR and SLA16 Isogenic Rats.
Autorzy:
Pértile RAN; Laboratory of Behavior Genetics, Department of Cellular Biology, Embryology and Genetics, Federal University of Santa Catarina, Florianópolis, Brazil.; Queensland Brain Institute, University of Queensland, Brisbane, QLD, 4072, Australia.
Corvino ME; Laboratory of Behavior Genetics, Department of Cellular Biology, Embryology and Genetics, Federal University of Santa Catarina, Florianópolis, Brazil.
Marchette RCN; Laboratory of Behavior Genetics, Department of Cellular Biology, Embryology and Genetics, Federal University of Santa Catarina, Florianópolis, Brazil.; Department of Pharmacology, Federal University of Santa Catarina, Florianópolis, Brazil.
Pavesi E; Department of Pharmacology, Federal University of Santa Catarina, Florianópolis, Brazil.
Cavalli J; Laboratory of Behavior Genetics, Department of Cellular Biology, Embryology and Genetics, Federal University of Santa Catarina, Florianópolis, Brazil.
Ramos A; Laboratory of Behavior Genetics, Department of Cellular Biology, Embryology and Genetics, Federal University of Santa Catarina, Florianópolis, Brazil.
Izídio GS; Laboratory of Behavior Genetics, Department of Cellular Biology, Embryology and Genetics, Federal University of Santa Catarina, Florianópolis, Brazil. .; Department of Pharmacology, Federal University of Santa Catarina, Florianópolis, Brazil. .
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Źródło:
Behavior genetics [Behav Genet] 2017 Sep; Vol. 47 (5), pp. 552-563. Date of Electronic Publication: 2017 Aug 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Behavior, Animal/*drug effects
Locomotion/*drug effects
Rats, Mutant Strains/*metabolism
Animals ; Anxiety ; Dopamine/metabolism ; Dopamine D2 Receptor Antagonists/metabolism ; Drug Administration Routes ; Haloperidol/pharmacology ; Hippocampus/drug effects ; Male ; Motor Activity/physiology ; Quinpirole/metabolism ; Quinpirole/pharmacology ; Rats ; Rats, Inbred SHR/genetics ; Rats, Inbred SHR/metabolism ; Rats, Mutant Strains/genetics ; Receptors, Dopamine D2/drug effects ; Receptors, Dopamine D2/metabolism
Czasopismo naukowe
Tytuł:
In a Prediabetic Model, Empagliflozin Improves Hepatic Lipid Metabolism Independently of Obesity and before Onset of Hyperglycemia.
Autorzy:
Hüttl M; Centre for Experimental Medicine, Institute for Clinical and Experimental Medicine, 14321 Prague, Czech Republic.
Markova I; Centre for Experimental Medicine, Institute for Clinical and Experimental Medicine, 14321 Prague, Czech Republic.
Miklankova D; Centre for Experimental Medicine, Institute for Clinical and Experimental Medicine, 14321 Prague, Czech Republic.
Zapletalova I; Department of Pharmacology, Faculty of Medicine and Dentistry, Palacky University Olomouc, 77900 Olomouc, Czech Republic.
Poruba M; Department of Pharmacology, Faculty of Medicine and Dentistry, Palacky University Olomouc, 77900 Olomouc, Czech Republic.
Haluzik M; Diabetes Centre, Institute for Clinical and Experimental Medicine, 14321 Prague, Czech Republic.
Vaněčkova I; Department of Experimental Hypertension, Institute of Physiology, Czech Academy of Sciences, 14220 Prague, Czech Republic.
Malinska H; Centre for Experimental Medicine, Institute for Clinical and Experimental Medicine, 14321 Prague, Czech Republic.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Oct 26; Vol. 22 (21). Date of Electronic Publication: 2021 Oct 26.
Typ publikacji:
Journal Article
MeSH Terms:
Benzhydryl Compounds/*pharmacology
Glucosides/*pharmacology
Lipid Metabolism/*drug effects
Liver/*drug effects
Liver/*metabolism
Prediabetic State/*drug therapy
Prediabetic State/*metabolism
Sodium-Glucose Transporter 2 Inhibitors/*pharmacology
Animals ; Cytochrome P-450 Enzyme System/metabolism ; Disease Models, Animal ; Disease Progression ; Hyperglycemia/drug therapy ; Hyperglycemia/etiology ; Hyperglycemia/metabolism ; Hyperlipoproteinemia Type IV/complications ; Hyperlipoproteinemia Type IV/drug therapy ; Hyperlipoproteinemia Type IV/metabolism ; Inflammation Mediators/metabolism ; Insulin Resistance ; Male ; Non-alcoholic Fatty Liver Disease/etiology ; Non-alcoholic Fatty Liver Disease/metabolism ; Non-alcoholic Fatty Liver Disease/prevention & control ; Obesity/complications ; Obesity/metabolism ; Oxidative Stress/drug effects ; Prediabetic State/complications ; Rats ; Rats, Mutant Strains ; Rats, Wistar
Czasopismo naukowe
Tytuł:
Fear Extinction and Predictive Trait-Like Inter-Individual Differences in Rats Lacking the Serotonin Transporter.
Autorzy:
Willadsen M; Behavioral Neuroscience, Experimental and Biological Psychology, Faculty of Psychology, Philipps-University of Marburg, Gutenberg-Str. 18, D-35032 Marburg, Germany.
Üngör M; Associative Learning, Experimental and Biological Psychology, Faculty of Psychology, Philipps-University of Marburg, Gutenberg-Str. 18, D-35032 Marburg, Germany.
Sługocka A; Department of Physiology, Faculty of Medicine in Katowice, Medical University of Silesia, 40-055 Katowice, Poland.
Schwarting RKW; Behavioral Neuroscience, Experimental and Biological Psychology, Faculty of Psychology, Philipps-University of Marburg, Gutenberg-Str. 18, D-35032 Marburg, Germany.; Center for Mind, Brain and Behavior, Philipps-University of Marburg, Hans-Meerwein-Str. 6, D-35032 Marburg, Germany.
Homberg JR; Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen Medical Centre, 6525 EN Nijmegen, The Netherlands.
Wöhr M; Behavioral Neuroscience, Experimental and Biological Psychology, Faculty of Psychology, Philipps-University of Marburg, Gutenberg-Str. 18, D-35032 Marburg, Germany.; Center for Mind, Brain and Behavior, Philipps-University of Marburg, Hans-Meerwein-Str. 6, D-35032 Marburg, Germany.; KU Leuven, Faculty of Psychology and Educational Sciences, Research Unit Brain and Cognition, Laboratory of Biological Psychology, Social and Affective Neuroscience Research Group, B-3000 Leuven, Belgium.; KU Leuven, Leuven Brain Institute, B-3000 Leuven, Belgium.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Jun 30; Vol. 22 (13). Date of Electronic Publication: 2021 Jun 30.
Typ publikacji:
Journal Article
MeSH Terms:
Behavior, Animal*
Fear*
Quantitative Trait Loci*
RNA-Binding Proteins/*genetics
Animals ; Rats ; Rats, Mutant Strains
Czasopismo naukowe
Tytuł:
Feasibility of deuterium magnetic resonance spectroscopy of 3-O-Methylglucose at 7 Tesla.
Autorzy:
Hartmann B; Institute of Radiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
Müller M; Institute of Radiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
Seyler L; Institute of Radiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
Bäuerle T; Institute of Radiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
Wilferth T; Institute of Radiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
Avdievitch N; Max Planck Institute for Biological Cybernetics, Tübingen, Germany.
Ruhm L; Max Planck Institute for Biological Cybernetics, Tübingen, Germany.
Henning A; Max Planck Institute for Biological Cybernetics, Tübingen, Germany.; Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, Texas, United States of America.
Lesiv A; Solvex Limited Liability Company, Moscow, Russia.
Ivashkin P; Solvex Limited Liability Company, Moscow, Russia.
Uder M; Institute of Radiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
Nagel AM; Institute of Radiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.; Division of Medical Physics in Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
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Źródło:
PloS one [PLoS One] 2021 Jun 07; Vol. 16 (6), pp. e0252935. Date of Electronic Publication: 2021 Jun 07 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Phantoms, Imaging*
3-O-Methylglucose/*metabolism
Bone Neoplasms/*secondary
Breast Neoplasms/*pathology
Deuterium/*chemistry
Magnetic Resonance Imaging/*methods
Magnetic Resonance Spectroscopy/*methods
Animals ; Biological Transport ; Bone Neoplasms/metabolism ; Breast Neoplasms/metabolism ; Cell Proliferation ; Feasibility Studies ; Female ; Rats ; Rats, Mutant Strains ; Rats, Nude ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł:
Defining Phenotype, Tropism, and Retinal Gene Therapy Using Adeno-Associated Viral Vectors (AAVs) in New-Born Brown Norway Rats with a Spontaneous Mutation in Crb1 .
Autorzy:
Boon N; Department of Ophthalmology, Leiden University Medical Center (LUMC), Albinusdreef 2, 2333 ZA Leiden, The Netherlands.
Alves CH; Department of Ophthalmology, Leiden University Medical Center (LUMC), Albinusdreef 2, 2333 ZA Leiden, The Netherlands.
Mulder AA; Department of Cell & Chemical Biology, Leiden University Medical Center (LUMC), 2300 RC Leiden, The Netherlands.
Andriessen CA; Department of Ophthalmology, Leiden University Medical Center (LUMC), Albinusdreef 2, 2333 ZA Leiden, The Netherlands.
Buck TM; Department of Ophthalmology, Leiden University Medical Center (LUMC), Albinusdreef 2, 2333 ZA Leiden, The Netherlands.
Quinn PMJ; Department of Ophthalmology, Leiden University Medical Center (LUMC), Albinusdreef 2, 2333 ZA Leiden, The Netherlands.
Vos RM; Department of Ophthalmology, Leiden University Medical Center (LUMC), Albinusdreef 2, 2333 ZA Leiden, The Netherlands.
Koster AJ; Department of Cell & Chemical Biology, Leiden University Medical Center (LUMC), 2300 RC Leiden, The Netherlands.
Jost CR; Department of Cell & Chemical Biology, Leiden University Medical Center (LUMC), 2300 RC Leiden, The Netherlands.
Wijnholds J; Department of Ophthalmology, Leiden University Medical Center (LUMC), Albinusdreef 2, 2333 ZA Leiden, The Netherlands.; Netherlands Institute for Neuroscience, Institute of the Royal Netherlands Academy of Arts and Sciences (KNAW), Meibergdreef 47, 1105 BA Amsterdam, The Netherlands.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Mar 30; Vol. 22 (7). Date of Electronic Publication: 2021 Mar 30.
Typ publikacji:
Journal Article
MeSH Terms:
Calcium-Binding Proteins/*genetics
Dependovirus/*physiology
Genetic Therapy/*methods
Nerve Tissue Proteins/*genetics
Retinal Dystrophies/*genetics
Animals ; Animals, Newborn ; Calcium-Binding Proteins/metabolism ; Carrier Proteins/genetics ; Dependovirus/genetics ; Ependymoglial Cells/metabolism ; Eye Proteins/genetics ; Genetic Vectors/administration & dosage ; Genetic Vectors/pharmacology ; Intravitreal Injections ; Membrane Proteins/genetics ; Mutation ; Nerve Tissue Proteins/metabolism ; Phenotype ; Rats ; Rats, Mutant Strains ; Retina/physiopathology ; Retinal Dystrophies/etiology ; Retinal Dystrophies/therapy ; Retinal Pigment Epithelium/metabolism ; Viral Tropism
Czasopismo naukowe
Tytuł:
Sacubitril/Valsartan Improves Diastolic Function But Not Skeletal Muscle Function in a Rat Model of HFpEF.
Autorzy:
Schauer A; Laboratory of Molecular and Experimental Cardiology, TU Dresden, Heart Center Dresden, 01307 Dresden, Germany.
Adams V; Laboratory of Molecular and Experimental Cardiology, TU Dresden, Heart Center Dresden, 01307 Dresden, Germany.
Augstein A; Laboratory of Molecular and Experimental Cardiology, TU Dresden, Heart Center Dresden, 01307 Dresden, Germany.
Jannasch A; Department of Cardiac Surgery, Carl Gustav Carus Faculty of Medicine, Technische Universität Dresden, Heart Centre Dresden, Fetscherstrasse 76, 01307 Dresden, Germany.
Draskowski R; Laboratory of Molecular and Experimental Cardiology, TU Dresden, Heart Center Dresden, 01307 Dresden, Germany.
Kirchhoff V; Laboratory of Molecular and Experimental Cardiology, TU Dresden, Heart Center Dresden, 01307 Dresden, Germany.
Goto K; Laboratory of Molecular and Experimental Cardiology, TU Dresden, Heart Center Dresden, 01307 Dresden, Germany.
Mittag J; Department of Cardiac Surgery, Carl Gustav Carus Faculty of Medicine, Technische Universität Dresden, Heart Centre Dresden, Fetscherstrasse 76, 01307 Dresden, Germany.
Galli R; Clinical Sensoring and Monitoring, Department of Anesthesiology and Intensive Care Medicine, Faculty of Medicine, TU Dresden, 01307 Dresden, Germany.
Männel A; Laboratory of Molecular and Experimental Cardiology, TU Dresden, Heart Center Dresden, 01307 Dresden, Germany.
Barthel P; Laboratory of Molecular and Experimental Cardiology, TU Dresden, Heart Center Dresden, 01307 Dresden, Germany.
Linke A; Laboratory of Molecular and Experimental Cardiology, TU Dresden, Heart Center Dresden, 01307 Dresden, Germany.
Winzer EB; Laboratory of Molecular and Experimental Cardiology, TU Dresden, Heart Center Dresden, 01307 Dresden, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Mar 30; Vol. 22 (7). Date of Electronic Publication: 2021 Mar 30.
Typ publikacji:
Journal Article
MeSH Terms:
Aminobutyrates/*pharmacology
Biphenyl Compounds/*pharmacology
Heart Failure/*drug therapy
Heart Failure/*physiopathology
Muscle, Skeletal/*drug effects
Valsartan/*pharmacology
Angiotensin Receptor Antagonists/pharmacology ; Animals ; Connectin/metabolism ; Cyclic GMP/blood ; Diastole/drug effects ; Diastole/physiology ; Disease Models, Animal ; Drug Combinations ; Electrocardiography ; Female ; Fibrosis ; Glycated Hemoglobin/analysis ; Muscle, Skeletal/physiology ; Muscular Atrophy/drug therapy ; Muscular Atrophy/physiopathology ; Natriuretic Peptide, Brain/blood ; Peptide Fragments/blood ; Phosphorylation/drug effects ; Rats, Mutant Strains ; Ventricular Function, Left/drug effects ; Rats
Czasopismo naukowe
Tytuł:
Complement C6 deficiency exacerbates pathophysiology after spinal cord injury.
Autorzy:
Su D; Department of Anatomy and Neurobiology, University of California, Irvine, Irvine, CA, USA.
Hooshmand MJ; Department of Anatomy and Neurobiology, University of California, Irvine, Irvine, CA, USA.; Institute for Memory Impairments and Neurological Disorders (iMIND), University of California, Irvine, Irvine, CA, USA.; Sue and Bill Gross Stem Cell Research Center, University of California, Irvine, Irvine, CA, USA.
Galvan MD; Department of Anatomy and Neurobiology, University of California, Irvine, Irvine, CA, USA.
Nishi RA; Sue and Bill Gross Stem Cell Research Center, University of California, Irvine, Irvine, CA, USA.
Cummings BJ; Department of Anatomy and Neurobiology, University of California, Irvine, Irvine, CA, USA.; Institute for Memory Impairments and Neurological Disorders (iMIND), University of California, Irvine, Irvine, CA, USA.; Sue and Bill Gross Stem Cell Research Center, University of California, Irvine, Irvine, CA, USA.; Department of Physical Medicine and Rehabilitation, University of California, Irvine, CA, USA.
Anderson AJ; Department of Anatomy and Neurobiology, University of California, Irvine, Irvine, CA, USA. .; Institute for Memory Impairments and Neurological Disorders (iMIND), University of California, Irvine, Irvine, CA, USA. .; Sue and Bill Gross Stem Cell Research Center, University of California, Irvine, Irvine, CA, USA. .; Department of Physical Medicine and Rehabilitation, University of California, Irvine, CA, USA. .
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Źródło:
Scientific reports [Sci Rep] 2020 Nov 11; Vol. 10 (1), pp. 19500. Date of Electronic Publication: 2020 Nov 11.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Complement C6/*deficiency
Hereditary Complement Deficiency Diseases/*complications
Spinal Cord Injuries/*metabolism
Spinal Cord Injuries/*physiopathology
Animals ; Behavior, Animal ; Complement C6/genetics ; Complement Membrane Attack Complex/genetics ; Complement Membrane Attack Complex/metabolism ; Disease Models, Animal ; Female ; Genotype ; Glial Fibrillary Acidic Protein/metabolism ; Gray Matter/cytology ; Gray Matter/metabolism ; Hereditary Complement Deficiency Diseases/genetics ; Heterozygote ; Locomotion ; Male ; Myelin Basic Protein/metabolism ; Rats, Mutant Strains ; Selective Breeding ; Spinal Cord Injuries/etiology ; Spinal Cord Injuries/genetics ; Thoracic Vertebrae/injuries ; White Matter/cytology ; White Matter/metabolism
SCR Disease Name:
Complement Component 6 Deficiency
Czasopismo naukowe
Tytuł:
Effective Differentiation and Biological Characterization of Retinal Pigment Epithelium Derived from Human Induced Pluripotent Stem Cells.
Autorzy:
Shrestha R; Institute of Medical Sciences, Tzu Chi University , Hualien, Taiwan.; Institute of Eye Research, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation , Hualien, Taiwan.
Wen YT; Institute of Eye Research, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation , Hualien, Taiwan.
Tsai RK; Institute of Medical Sciences, Tzu Chi University , Hualien, Taiwan.; Institute of Eye Research, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation , Hualien, Taiwan.
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Źródło:
Current eye research [Curr Eye Res] 2020 Sep; Vol. 45 (9), pp. 1155-1167. Date of Electronic Publication: 2020 Feb 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Differentiation/*physiology
Induced Pluripotent Stem Cells/*cytology
Photoreceptor Cells, Vertebrate/*physiology
Retinal Degeneration/*surgery
Retinal Pigment Epithelium/*physiology
Animals ; Blotting, Western ; Cell Transplantation ; Electroretinography ; Epidermal Cells ; Heterografts ; Humans ; Immunohistochemistry ; Keratinocytes/cytology ; Male ; Microscopy, Electron, Transmission ; Opsins/metabolism ; Phagocytosis/physiology ; Photoreceptor Cells, Vertebrate/ultrastructure ; Rats, Mutant Strains ; Real-Time Polymerase Chain Reaction ; Retinal Degeneration/metabolism ; Retinal Degeneration/pathology ; Retinal Pigment Epithelium/transplantation ; Rhodopsin/metabolism ; Tomography, Optical Coherence
Czasopismo naukowe
Tytuł:
The deficiency of myelin in the mutant taiep rat induces a differential immune response related to protection from the human parasite Trichinella spiralis.
Autorzy:
Nava-Castro KE; Laboratorio de Genotoxicología y Mutagénesis Ambientales, Departamento de Genotoxicología y Medicina Ambientales, Centro de Ciencias de la Atmósfera, Universidad Nacional Autónoma de México, Ciudad de México, México.
Cortes C; Institute of Physiology, Benemérita Universidad Autónoma de Puebla, Puebla, México.
Eguibar JR; Institute of Physiology, Benemérita Universidad Autónoma de Puebla, Puebla, México.; Research Office of the Vice-Rectory of Research and Postgraduate Studies, Benemérita Universidad Autónoma de Puebla, Puebla, México.
Del Rio-Araiza VH; Departamento de Parasitología, Facultad de Veterinaria, Universidad Nacional Autónoma de México, Ciudad de México, México.
Hernández-Bello R; Departamento de Microbiología, Facultad de Medicina, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, México.
Morales-Montor J; Departamento de Inmunología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Ciudad de México, México.
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Źródło:
PloS one [PLoS One] 2020 Aug 20; Vol. 15 (8), pp. e0231803. Date of Electronic Publication: 2020 Aug 20 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Myelin Sheath/*genetics
Myelin Sheath/*metabolism
Trichinella spiralis/*pathogenicity
Animals ; Demyelinating Diseases/pathology ; Disease Models, Animal ; Male ; Parasites ; Rats ; Rats, Mutant Strains/immunology ; Rats, Sprague-Dawley/genetics ; Rats, Sprague-Dawley/immunology ; Tremor/pathology ; Trichinella spiralis/metabolism
Czasopismo naukowe
Tytuł:
Diabetes-Induced Inflammation and Vascular Alterations in the Goto-Kakizaki Rat Retina.
Autorzy:
Hachana S; École d'optométrie, Université de Montréal , Montréal, Québec, Canada.; Département de pharmacologie et physiologie, Université de Montréal , Montréal, Québec, Canada.
Pouliot M; École d'optométrie, Université de Montréal , Montréal, Québec, Canada.; Département de pharmacologie et physiologie, Université de Montréal , Montréal, Québec, Canada.
Couture R; Département de pharmacologie et physiologie, Université de Montréal , Montréal, Québec, Canada.
Vaucher E; École d'optométrie, Université de Montréal , Montréal, Québec, Canada.
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Źródło:
Current eye research [Curr Eye Res] 2020 Aug; Vol. 45 (8), pp. 965-974. Date of Electronic Publication: 2020 Jan 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Diabetes Mellitus, Type 2/*pathology
Diabetic Retinopathy/*pathology
Retinal Vessels/*pathology
Retinitis/*pathology
Animals ; Collagen Type I/metabolism ; Diabetes Mellitus, Type 2/metabolism ; Diabetic Retinopathy/metabolism ; Disease Models, Animal ; Fibronectins/metabolism ; Glial Fibrillary Acidic Protein/metabolism ; Gliosis/pathology ; Immunohistochemistry ; Inflammation/metabolism ; Inflammation/pathology ; Lipid Metabolism ; Macrophages/pathology ; Male ; Microscopy, Confocal ; Rats, Mutant Strains ; Rats, Wistar ; Receptor, Bradykinin B1/metabolism ; Retinal Pigment Epithelium/metabolism ; Retinal Pigment Epithelium/pathology ; Retinal Vessels/metabolism ; Retinitis/metabolism ; Vascular Endothelial Growth Factor A/metabolism
Czasopismo naukowe
Tytuł:
Modelling the genetic contribution to mental illness: a timely end for the psychiatric rodent?
Autorzy:
Davis BA; MRC Centre for Neuropsychiatric Genetics and Genomics, Neuroscience and Mental Health Research Institute, Cardiff University, Hadyn Ellis Building, Maindy Road, Cardiff, CF24 4HQ, UK.
Isles AR
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Źródło:
The European journal of neuroscience [Eur J Neurosci] 2014 Jun; Vol. 39 (11), pp. 1933-42. Date of Electronic Publication: 2014 May 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Disease Models, Animal*
Mental Disorders/*genetics
Mice, Mutant Strains/*genetics
Rats, Mutant Strains/*genetics
Animals ; Gene-Environment Interaction ; Genetic Pleiotropy ; Genome-Wide Association Study/methods ; Mental Disorders/physiopathology ; Mice ; Mice, Mutant Strains/physiology ; Polymorphism, Genetic ; Rats ; Rats, Mutant Strains/physiology
Czasopismo naukowe
Tytuł:
Paraoxonase 1 knockout rats have impaired T cell development at the CD4/CD8 double-negative to double-positive transition stage.
Autorzy:
Bai L; Key Laboratory of Human Disease Comparative Medicine, Ministry of Health, Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences and Comparative Medical Center, Peking Union Medical College, Beijing, China.
Shi G; Key Laboratory of Human Disease Comparative Medicine, Ministry of Health, Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences and Comparative Medical Center, Peking Union Medical College, Beijing, China.
Ma Y; Key Laboratory of Human Disease Comparative Medicine, Ministry of Health, Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences and Comparative Medical Center, Peking Union Medical College, Beijing, China.
Zhang L; Key Laboratory of Human Disease Comparative Medicine, Ministry of Health, Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences and Comparative Medical Center, Peking Union Medical College, Beijing, China.
Guan F; Key Laboratory of Human Disease Comparative Medicine, Ministry of Health, Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences and Comparative Medical Center, Peking Union Medical College, Beijing, China.
Zhang X; Key Laboratory of Human Disease Comparative Medicine, Ministry of Health, Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences and Comparative Medical Center, Peking Union Medical College, Beijing, China.
Xu Y; Key Laboratory of Human Disease Comparative Medicine, Ministry of Health, Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences and Comparative Medical Center, Peking Union Medical College, Beijing, China.
Chen H; Department of Biochemistry and Molecular Biology, State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Zhang L; Key Laboratory of Human Disease Comparative Medicine, Ministry of Health, Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences and Comparative Medical Center, Peking Union Medical College, Beijing, China. .
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Źródło:
Scientific reports [Sci Rep] 2018 Sep 27; Vol. 8 (1), pp. 14457. Date of Electronic Publication: 2018 Sep 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Aryldialkylphosphatase*/genetics
Aryldialkylphosphatase*/immunology
CD4 Antigens*/genetics
CD4 Antigens*/immunology
CD8 Antigens*/genetics
CD8 Antigens*/immunology
Gene Knockout Techniques*
Thymocytes/*immunology
Thymus Gland/*immunology
Animals ; Rats ; Rats, Mutant Strains ; Rats, Sprague-Dawley ; Thymocytes/cytology ; Thymus Gland/cytology
Czasopismo naukowe
Tytuł:
The C3H/HeJ mouse and DEBR rat models for alopecia areata: review of preclinical drug screening approaches and results.
Autorzy:
Sun J; The Jackson Laboratory, Bar Harbor, ME 04609-1500, USA.
Silva KA
McElwee KJ
King LE Jr
Sundberg JP
Pokaż więcej
Źródło:
Experimental dermatology [Exp Dermatol] 2008 Oct; Vol. 17 (10), pp. 793-805.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Disease Models, Animal*
Mice, Inbred C3H*
Rats, Mutant Strains*
Alopecia Areata/*drug therapy
Alopecia Areata/genetics ; Alopecia Areata/pathology ; Animals ; Drug Evaluation, Preclinical/methods ; Mice ; Rats
Czasopismo naukowe
Tytuł:
A set of highly informative rat simple sequence length polymorphism (SSLP) markers and genetically defined rat strains.
Autorzy:
Mashimo T; Institute of Laboratory Animals, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan. />Voigt B
Tsurumi T
Naoi K
Nakanishi S
Yamasaki K
Kuramoto T
Serikawa T
Pokaż więcej
Źródło:
BMC genetics [BMC Genet] 2006 Apr 04; Vol. 7, pp. 19. Date of Electronic Publication: 2006 Apr 04.
Typ publikacji:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Polymorphism, Genetic/*genetics
Rats, Inbred Strains/*genetics
Rats, Mutant Strains/*genetics
Animals ; Animals, Congenic/genetics ; Animals, Genetically Modified/genetics ; Breeding ; Crosses, Genetic ; Female ; Genetic Markers ; Genome ; Genotype ; Japan ; Male ; Phenotype ; Phylogeny ; Rats ; Rats, Inbred Strains/classification ; Rats, Mutant Strains/classification ; Specific Pathogen-Free Organisms
Czasopismo naukowe
Tytuł:
Production of knockout rats using ENU mutagenesis and a yeast-based screening assay.
Autorzy:
Zan Y; Department of Oncology, McArdle Laboratory for Cancer Research, 1400 University Avenue, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.
Haag JD
Chen KS
Shepel LA
Wigington D
Wang YR
Hu R
Lopez-Guajardo CC
Brose HL
Porter KI
Leonard RA
Hitt AA
Schommer SL
Elegbede AF
Gould MN
Pokaż więcej
Źródło:
Nature biotechnology [Nat Biotechnol] 2003 Jun; Vol. 21 (6), pp. 645-51. Date of Electronic Publication: 2003 May 18.
Typ publikacji:
Evaluation Study; Journal Article; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Mutagenesis, Site-Directed*
Ethylnitrosourea/*administration & dosage
Gene Expression Regulation/*drug effects
Gene Targeting/*methods
Rats, Mutant Strains/*genetics
Animals ; BRCA1 Protein/deficiency ; BRCA1 Protein/genetics ; BRCA2 Protein/deficiency ; BRCA2 Protein/genetics ; Cells, Cultured ; Male ; Protein Engineering/methods ; Rats ; Rats, Mutant Strains/metabolism ; Rats, Sprague-Dawley ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Yeasts/drug effects ; Yeasts/isolation & purification
Czasopismo naukowe
Tytuł:
BB rat lyp mutation and Type 1 diabetes.
Autorzy:
Ramanathan S; Arthritis and Immune Disorder Research Centre at the University Health Network, University of Toronto, Ontario, Canada.
Poussier P
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Źródło:
Immunological reviews [Immunol Rev] 2001 Dec; Vol. 184, pp. 161-71.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Diabetes Mellitus, Type 1/*genetics
Protein Tyrosine Phosphatases/*genetics
Rats, Mutant Strains/*genetics
Animals ; Diabetes Mellitus, Type 1/immunology ; Humans ; Lymphopenia/immunology ; Lymphopenia/physiopathology ; Mice ; Mitosis ; Protein Tyrosine Phosphatase, Non-Receptor Type 1 ; Protein Tyrosine Phosphatase, Non-Receptor Type 22 ; Rats ; Rats, Mutant Strains/immunology ; T-Lymphocytes/immunology
Czasopismo naukowe
Tytuł:
Autophagy precedes apoptosis among at risk cerebellar Purkinje cells in the shaker mutant rat: an ultrastructural study.
Autorzy:
Erekat NS; a Department of Anatomy, Faculty of Medicine , Jordan University of Science and Technology (JUST) , Irbid , Jordan.
Pokaż więcej
Źródło:
Ultrastructural pathology [Ultrastruct Pathol] 2018 Mar-Apr; Vol. 42 (2), pp. 162-169. Date of Electronic Publication: 2018 Feb 08.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis/*physiology
Autophagy/*physiology
Nerve Degeneration/*pathology
Purkinje Cells/*pathology
Purkinje Cells/*ultrastructure
Animals ; Cerebellar Ataxia/pathology ; Disease Models, Animal ; Essential Tremor/pathology ; Rats ; Rats, Mutant Strains
Czasopismo naukowe

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