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Wyszukujesz frazę ""Rats, Sprague-Dawley"" wg kryterium: Temat


Tytuł :
Fabrication of PLGA in situ forming implants and study on their correlation of in vitro release profiles with in vivo performances.
Autorzy :
Yang S; Chemical and Pharmaceutical Engineering Institute, Hebei University of Science and Technology, Hebei, China.
Hu M; Chemical and Pharmaceutical Engineering Institute, Hebei University of Science and Technology, Hebei, China.
Liu W; Chemical and Pharmaceutical Engineering Institute, Hebei University of Science and Technology, Hebei, China.
Hou N; Chemical and Pharmaceutical Engineering Institute, Hebei University of Science and Technology, Hebei, China.
Yin K; Chemical and Pharmaceutical Engineering Institute, Hebei University of Science and Technology, Hebei, China.
Shen C; Chemical and Pharmaceutical Engineering Institute, Hebei University of Science and Technology, Hebei, China.
Shang Q; Chemical and Pharmaceutical Engineering Institute, Hebei University of Science and Technology, Hebei, China.
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Źródło :
Journal of biomaterials science. Polymer edition [J Biomater Sci Polym Ed] 2021 Jun; Vol. 32 (8), pp. 994-1008. Date of Electronic Publication: 2021 Mar 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Rats, Sprague-Dawley*
Animals ; Drug Implants ; Molecular Weight ; Rats ; Solvents
Czasopismo naukowe
Tytuł :
Incidences and Range of Spontaneous Microscopic Lesions in the Eye of Sprague-Dawley Rats and Han Wistar Rats Used in Toxicity Studies.
Autorzy :
Cloup E; 63899Covance Laboratories, Huntingdon, United Kingdom.
Romao P; 63899Covance Laboratories, Eye, United Kingdom.
Taylor I; 63899Covance Laboratories, Eye, United Kingdom.
Mowat V; 63899Covance Laboratories, Huntingdon, United Kingdom.
Mukaratirwa S; 63899Covance Laboratories, Huntingdon, United Kingdom.
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Źródło :
Toxicologic pathology [Toxicol Pathol] 2021 Apr; Vol. 49 (3), pp. 581-589. Date of Electronic Publication: 2020 Aug 25.
Typ publikacji :
Journal Article
MeSH Terms :
Rats, Sprague-Dawley*
Animals ; Female ; Incidence ; Male ; Rats ; Rats, Wistar ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Estrogen synthesis in the stomach of Sprague-Dawley rats: comparison to Wistar rats.
Autorzy :
Kobayashi H; Department of Anatomy and Structural Science, Faculty of Medicine, Yamagata University, 2-2-2 Iida-nishi, Yamagata 990-9585, Japan.
Shirasawa N; Department of Rehabilitation, Faculty of Medical Science and Welfare, Tohoku Bunka Gakuen University, Aoba-ku, Sendai, Miyagi 980-8579, Japan.
Naito A; Department of Anatomy and Structural Science, Faculty of Medicine, Yamagata University, 2-2-2 Iida-nishi, Yamagata 990-9585, Japan.
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Źródło :
Experimental animals [Exp Anim] 2021 Feb 06; Vol. 70 (1), pp. 63-72. Date of Electronic Publication: 2020 Sep 25.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Rats, Sprague-Dawley*
Estrogens/*biosynthesis
Parietal Cells, Gastric/*metabolism
Animals ; Aromatase/genetics ; Aromatase/metabolism ; Aromatase/physiology ; Estrogens/metabolism ; Gastric Mucosa/cytology ; Gastric Mucosa/enzymology ; Gastric Mucosa/metabolism ; Gene Expression ; Male ; Parietal Cells, Gastric/enzymology ; Portal Vein/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Tinnitus rat model generated by laser-induced shock wave; a platform for analyzing the central nervous system after tinnitus generation.
Autorzy :
Niwa K; Department of Anatomy and Neurobiology, National Defense Medical College, Tokorozawa, 359-8513, Japan; Department of Otolaryngology, Head and Neck Surgery, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama 359-8513, Japan.
Mizutari K; Department of Otolaryngology, Head and Neck Surgery, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama 359-8513, Japan. Electronic address: .
Matsui T; Department of Anatomy and Neurobiology, National Defense Medical College, Tokorozawa, 359-8513, Japan.
Kawauchi S; Division of Bioinformation and Therapeutic Systems, National Defense Medical College Research Institute, Tokorozawa, 359-8513, Japan.
Sato S; Division of Bioinformation and Therapeutic Systems, National Defense Medical College Research Institute, Tokorozawa, 359-8513, Japan.
Shiotani A; Department of Otolaryngology, Head and Neck Surgery, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama 359-8513, Japan.
Kobayashi Y; Department of Anatomy and Neurobiology, National Defense Medical College, Tokorozawa, 359-8513, Japan.
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Źródło :
Auris, nasus, larynx [Auris Nasus Larynx] 2021 Feb; Vol. 48 (1), pp. 82-89. Date of Electronic Publication: 2020 Aug 04.
Typ publikacji :
Journal Article
MeSH Terms :
Disease Models, Animal*
Lasers*
Rats, Sprague-Dawley*
Tinnitus*/etiology
Tinnitus*/pathology
Tinnitus*/physiopathology
Brain/*pathology
Animals ; Central Nervous System/physiopathology ; Evoked Potentials, Auditory, Brain Stem ; Hearing Loss/diagnosis ; Hearing Loss/etiology ; High-Energy Shock Waves ; Limbic System/pathology ; Male ; Rats
Czasopismo naukowe
Tytuł :
Exposure to DEHP induces testis toxicity and injury through the ROS/mTOR/NLRP3 signaling pathway in immature rats.
Autorzy :
Hong Y; Department of Urology, Children's Hospital of Chongqing Medical University, Chongqing 400014, PR China; Pediatric Research Institute, Children's Hospital of Chongqing Medical University, Chongqing 400014, PR China; China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Children's Hospital of Chongqing Medical University, Chongqing 400014, PR China; National Clinical Research Center for Child Health and Disorders, Chongqing 400014, PR China; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing 400014, PR China; Chongqing Key Laboratory of Pediatrics, Chongqing 400014, PR China; Chongqing Key Laboratory of Children Urogenital Development and Tissue Engineering, Chongqing 400014, PR China.
Zhou Y; Department of Urology, Children's Hospital of Chongqing Medical University, Chongqing 400014, PR China; Pediatric Research Institute, Children's Hospital of Chongqing Medical University, Chongqing 400014, PR China; China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Children's Hospital of Chongqing Medical University, Chongqing 400014, PR China; National Clinical Research Center for Child Health and Disorders, Chongqing 400014, PR China; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing 400014, PR China; Chongqing Key Laboratory of Pediatrics, Chongqing 400014, PR China; Chongqing Key Laboratory of Children Urogenital Development and Tissue Engineering, Chongqing 400014, PR China.
Shen L; Pediatric Research Institute, Children's Hospital of Chongqing Medical University, Chongqing 400014, PR China; China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Children's Hospital of Chongqing Medical University, Chongqing 400014, PR China; National Clinical Research Center for Child Health and Disorders, Chongqing 400014, PR China; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing 400014, PR China; Chongqing Key Laboratory of Pediatrics, Chongqing 400014, PR China; Chongqing Key Laboratory of Children Urogenital Development and Tissue Engineering, Chongqing 400014, PR China.
Wei Y; Department of Urology, Children's Hospital of Chongqing Medical University, Chongqing 400014, PR China; Pediatric Research Institute, Children's Hospital of Chongqing Medical University, Chongqing 400014, PR China; China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Children's Hospital of Chongqing Medical University, Chongqing 400014, PR China; National Clinical Research Center for Child Health and Disorders, Chongqing 400014, PR China; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing 400014, PR China; Chongqing Key Laboratory of Pediatrics, Chongqing 400014, PR China; Chongqing Key Laboratory of Children Urogenital Development and Tissue Engineering, Chongqing 400014, PR China.
Long C; Pediatric Research Institute, Children's Hospital of Chongqing Medical University, Chongqing 400014, PR China; China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Children's Hospital of Chongqing Medical University, Chongqing 400014, PR China; National Clinical Research Center for Child Health and Disorders, Chongqing 400014, PR China; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing 400014, PR China; Chongqing Key Laboratory of Pediatrics, Chongqing 400014, PR China; Chongqing Key Laboratory of Children Urogenital Development and Tissue Engineering, Chongqing 400014, PR China.
Fu Y; Department of Urology, Children's Hospital of Chongqing Medical University, Chongqing 400014, PR China; Pediatric Research Institute, Children's Hospital of Chongqing Medical University, Chongqing 400014, PR China; China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Children's Hospital of Chongqing Medical University, Chongqing 400014, PR China; National Clinical Research Center for Child Health and Disorders, Chongqing 400014, PR China; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing 400014, PR China; Chongqing Key Laboratory of Pediatrics, Chongqing 400014, PR China; Chongqing Key Laboratory of Children Urogenital Development and Tissue Engineering, Chongqing 400014, PR China.
Wu H; Department of Urology, Children's Hospital of Chongqing Medical University, Chongqing 400014, PR China; Pediatric Research Institute, Children's Hospital of Chongqing Medical University, Chongqing 400014, PR China; China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Children's Hospital of Chongqing Medical University, Chongqing 400014, PR China; National Clinical Research Center for Child Health and Disorders, Chongqing 400014, PR China; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing 400014, PR China; Chongqing Key Laboratory of Pediatrics, Chongqing 400014, PR China; Chongqing Key Laboratory of Children Urogenital Development and Tissue Engineering, Chongqing 400014, PR China.
Wang J; Department of Urology, Children's Hospital of Chongqing Medical University, Chongqing 400014, PR China; Pediatric Research Institute, Children's Hospital of Chongqing Medical University, Chongqing 400014, PR China; China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Children's Hospital of Chongqing Medical University, Chongqing 400014, PR China; National Clinical Research Center for Child Health and Disorders, Chongqing 400014, PR China; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing 400014, PR China; Chongqing Key Laboratory of Pediatrics, Chongqing 400014, PR China; Chongqing Key Laboratory of Children Urogenital Development and Tissue Engineering, Chongqing 400014, PR China.
Wu Y; Department of Urology, Children's Hospital of Chongqing Medical University, Chongqing 400014, PR China; Pediatric Research Institute, Children's Hospital of Chongqing Medical University, Chongqing 400014, PR China; China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Children's Hospital of Chongqing Medical University, Chongqing 400014, PR China; National Clinical Research Center for Child Health and Disorders, Chongqing 400014, PR China; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing 400014, PR China; Chongqing Key Laboratory of Pediatrics, Chongqing 400014, PR China; Chongqing Key Laboratory of Children Urogenital Development and Tissue Engineering, Chongqing 400014, PR China.
Wu S; Department of Urology, Children's Hospital of Chongqing Medical University, Chongqing 400014, PR China; China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Children's Hospital of Chongqing Medical University, Chongqing 400014, PR China; National Clinical Research Center for Child Health and Disorders, Chongqing 400014, PR China; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing 400014, PR China; Chongqing Key Laboratory of Pediatrics, Chongqing 400014, PR China; Chongqing Key Laboratory of Children Urogenital Development and Tissue Engineering, Chongqing 400014, PR China.
Wei G; Department of Urology, Children's Hospital of Chongqing Medical University, Chongqing 400014, PR China; China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Children's Hospital of Chongqing Medical University, Chongqing 400014, PR China; National Clinical Research Center for Child Health and Disorders, Chongqing 400014, PR China; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing 400014, PR China; Chongqing Key Laboratory of Pediatrics, Chongqing 400014, PR China; Chongqing Key Laboratory of Children Urogenital Development and Tissue Engineering, Chongqing 400014, PR China. Electronic address: .
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Źródło :
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2021 Dec 20; Vol. 227, pp. 112889. Date of Electronic Publication: 2021 Oct 11.
Typ publikacji :
Journal Article
MeSH Terms :
Diethylhexyl Phthalate*/toxicity
Testis*
Animals ; Male ; NLR Family, Pyrin Domain-Containing 3 Protein ; Rats ; Rats, Sprague-Dawley ; Reactive Oxygen Species ; Signal Transduction ; TOR Serine-Threonine Kinases
Czasopismo naukowe
Tytuł :
lncRNA AABR07005593.1 potentiates PM 2.5 -induced interleukin-6 expression by targeting MCCC1.
Autorzy :
Liao F; State Environmental Protection Key Laboratory of Environmental Pollution Health Risk Assessment, South China Institute of Environmental Sciences, Ministry of Ecology and Environment, Guangzhou 510535, China; School of Public Health, Guangxi Medical University, Nanning 530021, China.
Tan Y; State Environmental Protection Key Laboratory of Environmental Pollution Health Risk Assessment, South China Institute of Environmental Sciences, Ministry of Ecology and Environment, Guangzhou 510535, China.
Wang Y; State Environmental Protection Key Laboratory of Environmental Pollution Health Risk Assessment, South China Institute of Environmental Sciences, Ministry of Ecology and Environment, Guangzhou 510535, China.
Zhou C; School of Public Health and Management, YouJiang Medical University for Nationalities, Baise 533000, China.
Wang Q; School of Public Health, Guangxi Medical University, Nanning 530021, China.
Li J; School of Public Health, Guangxi Medical University, Nanning 530021, China.
He L; State Environmental Protection Key Laboratory of Environmental Pollution Health Risk Assessment, South China Institute of Environmental Sciences, Ministry of Ecology and Environment, Guangzhou 510535, China.
Peng X; State Environmental Protection Key Laboratory of Environmental Pollution Health Risk Assessment, South China Institute of Environmental Sciences, Ministry of Ecology and Environment, Guangzhou 510535, China. Electronic address: .
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Źródło :
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2021 Dec 15; Vol. 226, pp. 112834. Date of Electronic Publication: 2021 Oct 04.
Typ publikacji :
Journal Article
MeSH Terms :
RNA, Long Noncoding*/genetics
Animals ; Female ; Interleukin-6/genetics ; Male ; NF-kappa B/genetics ; Particulate Matter/toxicity ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Calcium alleviates fluoride-induced kidney damage via FAS/FASL, TNFR/TNF, DR5/TRAIL pathways in rats.
Autorzy :
Li H; College of Veterinary Medicine, Shanxi Agricultural University, Taigu 030801, Shanxi, PR China; Shanxi Key Laboratory of Environmental Veterinary Medicine, Shanxi Agricultural University, Taigu 030801, Shanxi, PR China.
Fan J; College of Veterinary Medicine, Shanxi Agricultural University, Taigu 030801, Shanxi, PR China; Shanxi Key Laboratory of Environmental Veterinary Medicine, Shanxi Agricultural University, Taigu 030801, Shanxi, PR China.
Zhao Y; College of Veterinary Medicine, Shanxi Agricultural University, Taigu 030801, Shanxi, PR China; Shanxi Key Laboratory of Environmental Veterinary Medicine, Shanxi Agricultural University, Taigu 030801, Shanxi, PR China.
Yang J; College of Veterinary Medicine, Shanxi Agricultural University, Taigu 030801, Shanxi, PR China; Shanxi Key Laboratory of Environmental Veterinary Medicine, Shanxi Agricultural University, Taigu 030801, Shanxi, PR China.
Xu H; College of Veterinary Medicine, Shanxi Agricultural University, Taigu 030801, Shanxi, PR China; Shanxi Key Laboratory of Environmental Veterinary Medicine, Shanxi Agricultural University, Taigu 030801, Shanxi, PR China.
Manthari RK; College of Veterinary Medicine, Shanxi Agricultural University, Taigu 030801, Shanxi, PR China; Shanxi Key Laboratory of Environmental Veterinary Medicine, Shanxi Agricultural University, Taigu 030801, Shanxi, PR China.
Cheng X; Department of Basic Science, Shanxi Agricultural University, Taigu 030801, Shanxi, PR China.
Wang J; College of Veterinary Medicine, Shanxi Agricultural University, Taigu 030801, Shanxi, PR China; Shanxi Key Laboratory of Environmental Veterinary Medicine, Shanxi Agricultural University, Taigu 030801, Shanxi, PR China.
Wang J; College of Veterinary Medicine, Shanxi Agricultural University, Taigu 030801, Shanxi, PR China; Shanxi Key Laboratory of Environmental Veterinary Medicine, Shanxi Agricultural University, Taigu 030801, Shanxi, PR China. Electronic address: .
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Źródło :
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2021 Dec 15; Vol. 226, pp. 112851. Date of Electronic Publication: 2021 Oct 04.
Typ publikacji :
Journal Article
MeSH Terms :
Calcium*/metabolism
Fluorides*/toxicity
Animals ; Apoptosis ; Calcium, Dietary ; Caspase 8 ; Fas Ligand Protein/genetics ; Kidney/metabolism ; Rats ; Rats, Sprague-Dawley ; Tumor Necrosis Factor-alpha/genetics ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł :
A homogeneous time-resolved fluorometric energy transfer assay for the binding assessment of FcRn with IgG antibodies.
Autorzy :
Song Y; Department of Immunoassay and Immunochemistry, Center for Drug Safety Evaluation and Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Pudong, Shanghai 201203,China.
Deng X; Department of Immunoassay and Immunochemistry, Center for Drug Safety Evaluation and Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Pudong, Shanghai 201203,China.
Shi W; CAS Key Laboratory of Receptor Research, CAS Center for Excellence in Molecular Cell Science, Center for Biotherapeutics Discovery Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Pudong, Shanghai 201203, China.
Tang F; CAS Key Laboratory of Receptor Research, CAS Center for Excellence in Molecular Cell Science, Center for Biotherapeutics Discovery Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Pudong, Shanghai 201203, China.
Huang W; CAS Key Laboratory of Receptor Research, CAS Center for Excellence in Molecular Cell Science, Center for Biotherapeutics Discovery Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Pudong, Shanghai 201203, China.
Gong L; Department of Immunoassay and Immunochemistry, Center for Drug Safety Evaluation and Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Pudong, Shanghai 201203,China. Electronic address: .
Qin Q; Department of Immunoassay and Immunochemistry, Center for Drug Safety Evaluation and Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Pudong, Shanghai 201203,China. Electronic address: .
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Źródło :
Journal of immunological methods [J Immunol Methods] 2021 Dec; Vol. 499, pp. 113180. Date of Electronic Publication: 2021 Nov 01.
Typ publikacji :
Journal Article
MeSH Terms :
Fluorescence Resonance Energy Transfer*
Histocompatibility Antigens Class I/*immunology
Immunoglobulin G/*immunology
Receptors, Fc/*immunology
Animals ; Binding Sites ; Histocompatibility Antigens Class I/blood ; Humans ; Immunoglobulin G/blood ; Rats ; Rats, Sprague-Dawley ; Receptors, Fc/blood ; Time Factors ; Trastuzumab/chemistry
Czasopismo naukowe
Tytuł :
Novel mutual prodrug of 5-fluorouracil and heme oxygenase-1 inhibitor (5-FU/HO-1 hybrid): design and preliminary in vitro evaluation.
Autorzy :
Salerno L; Department of Drug and Health Sciences, University of Catania, Catania, Italy.
Vanella L; Department of Drug and Health Sciences, University of Catania, Catania, Italy.
Sorrenti V; Department of Drug and Health Sciences, University of Catania, Catania, Italy.
Consoli V; Department of Drug and Health Sciences, University of Catania, Catania, Italy.
Ciaffaglione V; Department of Drug and Health Sciences, University of Catania, Catania, Italy.
Fallica AN; Department of Drug and Health Sciences, University of Catania, Catania, Italy.
Canale V; Department of Organic Chemistry, Jagiellonian University Medical College, Kraków, Poland.
Zajdel P; Department of Organic Chemistry, Jagiellonian University Medical College, Kraków, Poland.
Pignatello R; Department of Drug and Health Sciences, University of Catania, Catania, Italy.
Intagliata S; Department of Drug and Health Sciences, University of Catania, Catania, Italy.
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Źródło :
Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2021 Dec; Vol. 36 (1), pp. 1378-1386.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*pharmacology
Fluorouracil/*chemistry
Heme Oxygenase-1/*chemistry
Prodrugs/*chemistry
Prodrugs/*pharmacology
Animals ; Antineoplastic Agents/chemistry ; Cell Line, Tumor ; Drug Design ; Drug Screening Assays, Antitumor ; Humans ; Male ; Prodrugs/chemical synthesis ; Rats ; Rats, Sprague-Dawley ; Swine
Czasopismo naukowe
Tytuł :
The GSK-3β/β-Catenin Signaling-Mediated Brain-Derived Neurotrophic Factor Pathway Is Involved in Aluminum-Induced Impairment of Hippocampal LTP In Vivo.
Autorzy :
Zhang H; Department of Occupational Health, School of Public Health, Shanxi Medical University, Taiyuan, China.; Key Lab of Environmental Hazard and Health of Shanxi Province, Shanxi Medical University, Taiyuan, China.
Han Y; Department of Occupational Health, School of Public Health, Shanxi Medical University, Taiyuan, China.; Key Lab of Environmental Hazard and Health of Shanxi Province, Shanxi Medical University, Taiyuan, China.
Zhang L; Department of Occupational Health, School of Public Health, Shanxi Medical University, Taiyuan, China.; Key Lab of Environmental Hazard and Health of Shanxi Province, Shanxi Medical University, Taiyuan, China.
Jia X; Department of Occupational Health, School of Public Health, Shanxi Medical University, Taiyuan, China.; Key Lab of Environmental Hazard and Health of Shanxi Province, Shanxi Medical University, Taiyuan, China.
Niu Q; Department of Occupational Health, School of Public Health, Shanxi Medical University, Taiyuan, China. .; Key Lab of Environmental Hazard and Health of Shanxi Province, Shanxi Medical University, Taiyuan, China. .
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Źródło :
Biological trace element research [Biol Trace Elem Res] 2021 Dec; Vol. 199 (12), pp. 4635-4645. Date of Electronic Publication: 2021 Jan 18.
Typ publikacji :
Journal Article
MeSH Terms :
Brain-Derived Neurotrophic Factor*/metabolism
beta Catenin*/metabolism
Aluminum/toxicity ; Animals ; Glycogen Synthase Kinase 3 beta ; Hippocampus/metabolism ; Long-Term Potentiation ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Aging disrupts the temporal organization of antioxidant defenses in the heart of male rats and phase shifts circadian rhythms of systolic blood pressure.
Autorzy :
Altamirano FG; Laboratorio de Cronobiología, Instituto Multidisciplinario de Investigaciones Biológicas-San Luis (IMIBIO-SL), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) y Universidad Nacional de San Luis (UNSL), Ejército de los Andes 950, Bloque I, 1° Piso, D5700HHW, San Luis, Argentina.
Castro-Pascual IC; Laboratorio de Cronobiología, Instituto Multidisciplinario de Investigaciones Biológicas-San Luis (IMIBIO-SL), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) y Universidad Nacional de San Luis (UNSL), Ejército de los Andes 950, Bloque I, 1° Piso, D5700HHW, San Luis, Argentina.
Ferramola ML; Laboratorio de Cronobiología, Instituto Multidisciplinario de Investigaciones Biológicas-San Luis (IMIBIO-SL), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) y Universidad Nacional de San Luis (UNSL), Ejército de los Andes 950, Bloque I, 1° Piso, D5700HHW, San Luis, Argentina.; Facultad de Química, Bioquímica y Farmacia (FQByF), Universidad Nacional de San Luis (UNSL), San Luis, Argentina.
Tula ML; Facultad de Química, Bioquímica y Farmacia (FQByF), Universidad Nacional de San Luis (UNSL), San Luis, Argentina.
Delgado SM; Laboratorio de Cronobiología, Instituto Multidisciplinario de Investigaciones Biológicas-San Luis (IMIBIO-SL), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) y Universidad Nacional de San Luis (UNSL), Ejército de los Andes 950, Bloque I, 1° Piso, D5700HHW, San Luis, Argentina.; Facultad de Química, Bioquímica y Farmacia (FQByF), Universidad Nacional de San Luis (UNSL), San Luis, Argentina.
Anzulovich AC; Laboratorio de Cronobiología, Instituto Multidisciplinario de Investigaciones Biológicas-San Luis (IMIBIO-SL), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) y Universidad Nacional de San Luis (UNSL), Ejército de los Andes 950, Bloque I, 1° Piso, D5700HHW, San Luis, Argentina. .; Facultad de Química, Bioquímica y Farmacia (FQByF), Universidad Nacional de San Luis (UNSL), San Luis, Argentina. .
Lacoste MG; Laboratorio de Cronobiología, Instituto Multidisciplinario de Investigaciones Biológicas-San Luis (IMIBIO-SL), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) y Universidad Nacional de San Luis (UNSL), Ejército de los Andes 950, Bloque I, 1° Piso, D5700HHW, San Luis, Argentina. .; Facultad de Química, Bioquímica y Farmacia (FQByF), Universidad Nacional de San Luis (UNSL), San Luis, Argentina. .
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Źródło :
Biogerontology [Biogerontology] 2021 Dec; Vol. 22 (6), pp. 603-621. Date of Electronic Publication: 2021 Sep 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antioxidants*
Circadian Rhythm*
Aging ; Animals ; Blood Pressure ; Male ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
The PLGA nanoparticles for sustainable release of CGRP to ameliorate the inflammatory and vascular disorders in the lung of CGRP-deficient rats.
Autorzy :
Wang F; Higher Educational Key Laboratory for Nano Biomedical Technology of Fujian Province, School of Pharmacy, Nano Medical Technology Research Institute, Fujian Medical University, Fuzhou, China.
Deng Y; Higher Educational Key Laboratory for Nano Biomedical Technology of Fujian Province, School of Pharmacy, Nano Medical Technology Research Institute, Fujian Medical University, Fuzhou, China.
Wang J; Higher Educational Key Laboratory for Nano Biomedical Technology of Fujian Province, School of Pharmacy, Nano Medical Technology Research Institute, Fujian Medical University, Fuzhou, China.
Yu L; Higher Educational Key Laboratory for Nano Biomedical Technology of Fujian Province, School of Pharmacy, Nano Medical Technology Research Institute, Fujian Medical University, Fuzhou, China.
Ding F; Center for Reproductive Medicine, 1st Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Lian W; Center for Reproductive Medicine, 1st Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Liu Q; Center for Reproductive Medicine, 1st Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Lin X; Higher Educational Key Laboratory for Nano Biomedical Technology of Fujian Province, School of Pharmacy, Nano Medical Technology Research Institute, Fujian Medical University, Fuzhou, China.
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Źródło :
Drug delivery [Drug Deliv] 2021 Dec; Vol. 28 (1), pp. 865-872.
Typ publikacji :
Journal Article
MeSH Terms :
Calcitonin Gene-Related Peptide/*deficiency
Calcitonin Gene-Related Peptide/*pharmacology
Drug Carriers/*chemistry
Nanoparticles/*chemistry
Polylactic Acid-Polyglycolic Acid Copolymer/*chemistry
Animals ; Calcitonin Gene-Related Peptide/administration & dosage ; Chemistry, Pharmaceutical ; Delayed-Action Preparations ; Drug Liberation ; Inflammation/drug therapy ; Male ; Particle Size ; Rats ; Rats, Sprague-Dawley ; Vascular Diseases/drug therapy
Czasopismo naukowe
Tytuł :
Cardiac contractile dysfunction, during and following ischaemia, is attenuated by low-dose dietary fish oil in rats.
Autorzy :
Macartney MJ; Graduate Medicine, School of Medicine, University of Wollongong, Wollongong, Australia. .; Centre for Medical and Exercise Physiology, Faculty of Science Medicine and Health, University of Wollongong, Wollongong, NSW, 2522, Australia. .
Peoples GE; Graduate Medicine, School of Medicine, University of Wollongong, Wollongong, Australia.; Centre for Medical and Exercise Physiology, Faculty of Science Medicine and Health, University of Wollongong, Wollongong, NSW, 2522, Australia.
McLennan PL; Graduate Medicine, School of Medicine, University of Wollongong, Wollongong, Australia.; Centre for Medical and Exercise Physiology, Faculty of Science Medicine and Health, University of Wollongong, Wollongong, NSW, 2522, Australia.
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Źródło :
European journal of nutrition [Eur J Nutr] 2021 Dec; Vol. 60 (8), pp. 4495-4503. Date of Electronic Publication: 2021 Jun 13.
Typ publikacji :
Journal Article
MeSH Terms :
Fatty Acids, Omega-3*
Fish Oils*
Animals ; Cattle ; Docosahexaenoic Acids ; Eicosapentaenoic Acid ; Ischemia ; Male ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Icariin improves brain function decline in aging rats by enhancing neuronal autophagy through the AMPK/mTOR/ULK1 pathway.
Autorzy :
Zheng J; Medical College of China Three Gorges University, Yichang, P. R. Chinas.
Hu S; Medical College of China Three Gorges University, Yichang, P. R. Chinas.
Wang J; Medical College of China Three Gorges University, Yichang, P. R. Chinas.
Zhang X; Medical College of China Three Gorges University, Yichang, P. R. Chinas.
Yuan D; Medical College of China Three Gorges University, Yichang, P. R. Chinas.
Zhang C; Medical College of China Three Gorges University, Yichang, P. R. Chinas.
Liu C; Medical College of China Three Gorges University, Yichang, P. R. Chinas.
Wang T; Department of Pharmacy, College of Medicine, New Drug Innovation and Development Institute, Wuhan University of Science and Technology, Wuhan, Hubei Province, China.; Hubei Province Key Laboratory of Occupational Hazard Identification and Control, Wuhan University of Science and Technology, Wuhan, Hubei Province, China.
Zhou Z; Medical College of China Three Gorges University, Yichang, P. R. Chinas.
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Źródło :
Pharmaceutical biology [Pharm Biol] 2021 Dec; Vol. 59 (1), pp. 183-191.
Typ publikacji :
Comparative Study; Journal Article
MeSH Terms :
Autophagy/*drug effects
Brain/*drug effects
Flavonoids/*pharmacology
Neurons/*drug effects
AMP-Activated Protein Kinases/metabolism ; Aging/physiology ; Animals ; Autophagy-Related Protein-1 Homolog/metabolism ; Brain/pathology ; Dose-Response Relationship, Drug ; Epimedium/chemistry ; Flavonoids/administration & dosage ; Flavonoids/isolation & purification ; Neurons/pathology ; Rats ; Rats, Sprague-Dawley ; TOR Serine-Threonine Kinases/metabolism
Czasopismo naukowe
Tytuł :
Halloysites modified polyethylene glycol diacrylate/thiolated chitosan double network hydrogel combined with BMP-2 for rat skull regeneration.
Autorzy :
Sun QB; Department of Spine and Joint Surgery, The Third People's Hospital of Jinan, Jinan, Shandong, People's Republic of China.
Xu CP; Department of Orthopaedics, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong, P.R. China.
Li WQ; Engineering Technology Research Center for Sports Assistive Devices of Guangdong, Guangzhou Sport University, Guangzhou, China.
Meng QJ; Department of Spine and Joint Surgery, The Third People's Hospital of Jinan, Jinan, Shandong, People's Republic of China.
Qu HZ; Department of Spine and Joint Surgery, The Third People's Hospital of Jinan, Jinan, Shandong, People's Republic of China.
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Źródło :
Artificial cells, nanomedicine, and biotechnology [Artif Cells Nanomed Biotechnol] 2021 Dec; Vol. 49 (1), pp. 71-82.
Typ publikacji :
Journal Article; Video-Audio Media
MeSH Terms :
Bone Morphogenetic Protein 2*/chemistry
Bone Morphogenetic Protein 2*/pharmacology
Chitosan*/chemistry
Chitosan*/pharmacology
Hydrogels*/chemistry
Hydrogels*/pharmacology
Polyethylene Glycols*/chemistry
Polyethylene Glycols*/pharmacology
Skull*/injuries
Skull*/metabolism
Bone Regeneration/*drug effects
Clay/*chemistry
Animals ; Cell Line ; Mice ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Ivabradine protects rats against myocardial infarction through reinforcing autophagy via inhibiting PI3K/AKT/mTOR/p70S6K pathway.
Autorzy :
Dai Y; Department of Cardiology, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, P.R. China.
Chen Y; Department of Cardiology, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, P.R. China.
Wei G; Department of Cardiology, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, P.R. China.
Zha L; Department of Cardiology, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, P.R. China.
Li X; Department of Cardiology, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, P.R. China.
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Źródło :
Bioengineered [Bioengineered] 2021 Dec; Vol. 12 (1), pp. 1826-1837.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Autophagy*
Cardiotonic Agents/*therapeutic use
Ivabradine/*therapeutic use
Myocardial Infarction/*drug therapy
Phosphatidylinositol 3-Kinases/*metabolism
Proto-Oncogene Proteins c-akt/*metabolism
Ribosomal Protein S6 Kinases, 70-kDa/*metabolism
TOR Serine-Threonine Kinases/*metabolism
Animals ; Cardiotonic Agents/pharmacology ; Cytokines/metabolism ; Diastole/drug effects ; Heart Ventricles/drug effects ; Heart Ventricles/physiopathology ; Hemodynamics/drug effects ; Inflammation Mediators/metabolism ; Ivabradine/pharmacology ; Myocardial Infarction/pathology ; Myocardial Infarction/physiopathology ; Rats, Sprague-Dawley ; Signal Transduction ; Systole/drug effects
Czasopismo naukowe
Tytuł :
Yiqi Huoxue Recipe inhibits cardiomyocyte apoptosis caused by heart failure through Keap1/Nrf2/HIF-1α signaling pathway.
Autorzy :
Hu L; Internal medicine, Beijing Xiaotangshan Hospital, Beijing, China.
Xu Y; Department of Cardiopulmonary Rehabilitation, Beijing Xiaotangshan Hospital, Beijing, China.
Wang Q; Rehabilitation Department, Beijing Xiaotangshan Hospital, Beijing, China.
Liu M; Animal Laboratory, Medical Experimental Center, Chinese Academy of Chinese Medical Sciences, Beijing.
Meng L; Rehabilitation Department, Beijing Xiaotangshan Hospital, Beijing, China.
Yan D; Department of Cardiopulmonary Rehabilitation, Beijing Xiaotangshan Hospital, Beijing, China.
Hu H; Research Laboratory, Beijing Xiaotangshan Hospital, Beijing, China.
Xiao M; Rehabilitation Department, Beijing Xiaotangshan Hospital, Beijing, China.
Yin Z; Rehabilitation Department, Beijing Xiaotangshan Hospital, Beijing, China.
Li Y; Research Laboratory, Beijing Xiaotangshan Hospital, Beijing, China.
Kang X; Internal medicine, Beijing Xiaotangshan Hospital, Beijing, China.
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Źródło :
Bioengineered [Bioengineered] 2021 Dec; Vol. 12 (1), pp. 969-978.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis*/drug effects
Drugs, Chinese Herbal/*pharmacology
Heart Failure/*pathology
Hypoxia-Inducible Factor 1, alpha Subunit/*metabolism
Kelch-Like ECH-Associated Protein 1/*metabolism
Myocytes, Cardiac/*metabolism
Myocytes, Cardiac/*pathology
NF-E2-Related Factor 2/*metabolism
Animals ; Cell Survival/drug effects ; Disease Models, Animal ; Glucose/deficiency ; Heart Failure/complications ; Male ; Membrane Potential, Mitochondrial/drug effects ; Myocardial Infarction/complications ; Myocardial Infarction/pathology ; Myocytes, Cardiac/drug effects ; Oxygen ; Rats, Sprague-Dawley ; Reactive Oxygen Species/metabolism ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł :
Melamine and oxalate coexposure induces early kidney tubular injury through mitochondrial aberrations and oxidative stress.
Autorzy :
Wu MT; Ph.D. Program of Environmental and Occupational Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; Research Center for Environmental Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; Department of Family Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan. Electronic address: .
Wu CF; Research Center for Environmental Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. Electronic address: .
Liu CC; Research Center for Environmental Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; Department of Urology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan; Department of Urology, Pingtung Hospital, Ministry of Health and Welfare, Pingtung City, Taiwan. Electronic address: .
Tsai YC; Research Center for Environmental Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; Divisions of Nephrology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan. Electronic address: .
Chen CC; Research Center for Environmental Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; Institute of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan. Electronic address: .
Wang YH; Institute of Population Health Sciences, National Health Research Institutes, Miaoli, Taiwan. Electronic address: .
Hsieh TJ; Research Center for Environmental Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; Department of Marine Biotechnology and Resources, College of Marine Sciences, National Sun Yat-Sen University, Kaohsiung, Taiwan. Electronic address: .
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Źródło :
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2021 Dec 01; Vol. 225, pp. 112756. Date of Electronic Publication: 2021 Sep 08.
Typ publikacji :
Journal Article
MeSH Terms :
Oxalates*
Oxidative Stress*
Animals ; Kidney ; Mice ; Rats ; Rats, Sprague-Dawley ; Triazines
Czasopismo naukowe
Tytuł :
The Masquelet Technique: Can Disposable Polypropylene Syringes be an Alternative to Standard PMMA Spacers? A Rat Bone Defect Model.
Autorzy :
Mathieu L; Department of Orthopedic, Trauma and Reconstructive Surgery, Percy Military Hospital, Clamart, France.; French Military Health Service Academy, Ecole du Val-de-Grâce, Paris, France.
Murison JC; Department of Orthopedic, Trauma and Reconstructive Surgery, Percy Military Hospital, Clamart, France.
de Rousiers A; Department of Orthopedic, Trauma and Reconstructive Surgery, Percy Military Hospital, Clamart, France.
de l'Escalopier N; Department of Orthopedic, Trauma and Reconstructive Surgery, Percy Military Hospital, Clamart, France.
Lutomski D; Tissue Engineering and Proteomics Team, Université Paris, Bobigny, France.
Collombet JM; Military Biomedical Research Institute, Brétigny-sur-Orge, France.
Durand M; Military Biomedical Research Institute, Brétigny-sur-Orge, France.
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Źródło :
Clinical orthopaedics and related research [Clin Orthop Relat Res] 2021 Dec 01; Vol. 479 (12), pp. 2737-2751.
Typ publikacji :
Journal Article
MeSH Terms :
Disposable Equipment*
Syringes*
Bone Cements/*adverse effects
Bone Transplantation/*instrumentation
Polymethyl Methacrylate/*administration & dosage
Animals ; Bone Remodeling ; Bone Transplantation/methods ; Disease Models, Animal ; Equipment Design ; Male ; Polypropylenes ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
Exosome loaded genipin crosslinked hydrogel facilitates full thickness cutaneous wound healing in rat animal model.
Autorzy :
Li Q; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, PR China.
Gong S; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, PR China.
Yao W; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, PR China.
Yang Z; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, PR China.
Wang R; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, PR China.
Yu Z; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, PR China.
Wei M; Department of Pharmacology, School of Pharmacy, China Medical University, Shenyang, PR China.
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Źródło :
Drug delivery [Drug Deliv] 2021 Dec; Vol. 28 (1), pp. 884-893.
Typ publikacji :
Journal Article
MeSH Terms :
Exosomes/*metabolism
Hydrogels/*chemistry
Iridoids/*pharmacology
Skin/*drug effects
Wound Healing/*drug effects
Animals ; Cell Movement/drug effects ; Collagen/metabolism ; Drug Liberation ; Female ; Hydrogen-Ion Concentration ; Iridoids/administration & dosage ; Mesenchymal Stem Cells/drug effects ; Particle Size ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe

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