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Tytuł:
Quercetin ameliorates bone loss in OVX rats by modulating the intestinal flora-SCFAs-inflammatory signaling axis.
Autorzy:
Feng R; Department of Spine Surgery, Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan, Hubei Province 430074, PR China.
Wang Q; School of Sports Medicine, Wuhan Institute of Physical Education, Wuhan City, Hubei Province 430079, PR China.
Yu T; Hubei University of Traditional Chinese Medicine, Wuhan, Hubei Province 430060, PR China.
Hu H; Department of Spine Surgery, Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan, Hubei Province 430074, PR China; School of Sports Medicine, Wuhan Institute of Physical Education, Wuhan City, Hubei Province 430079, PR China; Hubei University of Traditional Chinese Medicine, Wuhan, Hubei Province 430060, PR China.
Wu G; Department of Spine Surgery, Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan, Hubei Province 430074, PR China; School of Sports Medicine, Wuhan Institute of Physical Education, Wuhan City, Hubei Province 430079, PR China; Hubei University of Traditional Chinese Medicine, Wuhan, Hubei Province 430060, PR China.
Duan X; Department of Spine Surgery, Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan, Hubei Province 430074, PR China.
Jiang R; Hubei University of Traditional Chinese Medicine, Wuhan, Hubei Province 430060, PR China.
Xu Y; School of Sports Medicine, Wuhan Institute of Physical Education, Wuhan City, Hubei Province 430079, PR China.
Huang Y; Department of Spine Surgery, Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan, Hubei Province 430074, PR China; School of Sports Medicine, Wuhan Institute of Physical Education, Wuhan City, Hubei Province 430079, PR China; Hubei University of Traditional Chinese Medicine, Wuhan, Hubei Province 430060, PR China. Electronic address: .
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Źródło:
International immunopharmacology [Int Immunopharmacol] 2024 Jul 30; Vol. 136, pp. 112341. Date of Electronic Publication: 2024 May 28.
Typ publikacji:
Journal Article
MeSH Terms:
Gastrointestinal Microbiome*/drug effects
Quercetin*/pharmacology
Quercetin*/therapeutic use
Fatty Acids, Volatile*/metabolism
Rats, Sprague-Dawley*
Ovariectomy*
Signal Transduction*/drug effects
Animals ; Female ; Rats ; Cytokines/metabolism ; Fecal Microbiota Transplantation ; Osteoporosis/drug therapy ; Disease Models, Animal ; Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/therapeutic use ; Humans ; Inflammation/drug therapy
Czasopismo naukowe
Tytuł:
Polyene phosphatidylcholine promotes tibial fracture healing in rats by stimulating angiogenesis dominated by the VEGFA/VEGFR2 signaling pathway.
Autorzy:
Chen X; School of Life Science, Beijing University of Chinese Medicine, Beijing, 100029, China.
Du J; School of Life Science, Beijing University of Chinese Medicine, Beijing, 100029, China.
Zhan W; School of Life Science, Beijing University of Chinese Medicine, Beijing, 100029, China.
Shao B; School of Life Science, Beijing University of Chinese Medicine, Beijing, 100029, China.
Jiang H; School of Life Science, Beijing University of Chinese Medicine, Beijing, 100029, China.
Chen Z; School of Life Science, Beijing University of Chinese Medicine, Beijing, 100029, China.
Wang C; School of Life Science, Beijing University of Chinese Medicine, Beijing, 100029, China. Electronic address: .
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Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2024 Jul 30; Vol. 719, pp. 150100. Date of Electronic Publication: 2024 May 11.
Typ publikacji:
Journal Article
MeSH Terms:
Fracture Healing*/drug effects
Vascular Endothelial Growth Factor Receptor-2*/metabolism
Vascular Endothelial Growth Factor Receptor-2*/genetics
Vascular Endothelial Growth Factor A*/metabolism
Vascular Endothelial Growth Factor A*/genetics
Tibial Fractures*/metabolism
Tibial Fractures*/drug therapy
Tibial Fractures*/pathology
Signal Transduction*/drug effects
Neovascularization, Physiologic*/drug effects
Human Umbilical Vein Endothelial Cells*/metabolism
Human Umbilical Vein Endothelial Cells*/drug effects
Rats, Sprague-Dawley*
Phosphatidylcholines*/pharmacology
Animals ; Humans ; Rats ; Male ; Polyenes/pharmacology ; Angiogenesis
Czasopismo naukowe
Tytuł:
Echinatin alleviates inflammation and pyroptosis in hypoxic-ischemic brain damage by inhibiting TLR4/ NF-κB pathway.
Autorzy:
Tao X; Department of Neonatology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China; Key Laboratory of Perinatal Medicine of Wenzhou, Wenzhou, Zhejiang, 325027, China; Key Laboratory of Structural Malformations in Children of Zhejiang Province, Wenzhou, Zhejiang, 325027, China.
Hu Y; Department of Neonatology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China; Key Laboratory of Perinatal Medicine of Wenzhou, Wenzhou, Zhejiang, 325027, China; Key Laboratory of Structural Malformations in Children of Zhejiang Province, Wenzhou, Zhejiang, 325027, China.
Mao N; Department of Neonatology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China; Key Laboratory of Perinatal Medicine of Wenzhou, Wenzhou, Zhejiang, 325027, China; Key Laboratory of Structural Malformations in Children of Zhejiang Province, Wenzhou, Zhejiang, 325027, China.
Shen M; Department of Neonatology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China; Key Laboratory of Perinatal Medicine of Wenzhou, Wenzhou, Zhejiang, 325027, China; Key Laboratory of Structural Malformations in Children of Zhejiang Province, Wenzhou, Zhejiang, 325027, China.
Fang M; Department of Neonatology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China; Key Laboratory of Perinatal Medicine of Wenzhou, Wenzhou, Zhejiang, 325027, China; Key Laboratory of Structural Malformations in Children of Zhejiang Province, Wenzhou, Zhejiang, 325027, China.
Zhang M; Department of Neonatology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China; Key Laboratory of Perinatal Medicine of Wenzhou, Wenzhou, Zhejiang, 325027, China; Key Laboratory of Structural Malformations in Children of Zhejiang Province, Wenzhou, Zhejiang, 325027, China.
Lou J; Department of Neonatology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China; Key Laboratory of Perinatal Medicine of Wenzhou, Wenzhou, Zhejiang, 325027, China; Key Laboratory of Structural Malformations in Children of Zhejiang Province, Wenzhou, Zhejiang, 325027, China.
Fang Y; Department of Neonatology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China; Key Laboratory of Perinatal Medicine of Wenzhou, Wenzhou, Zhejiang, 325027, China; Key Laboratory of Structural Malformations in Children of Zhejiang Province, Wenzhou, Zhejiang, 325027, China.
Guo X; Key Laboratory of Structural Malformations in Children of Zhejiang Province, Wenzhou, Zhejiang, 325027, China; Basic Medical Research Center, the Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang,325027, China. Electronic address: .
Lin Z; Department of Neonatology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China; Key Laboratory of Perinatal Medicine of Wenzhou, Wenzhou, Zhejiang, 325027, China; Key Laboratory of Structural Malformations in Children of Zhejiang Province, Wenzhou, Zhejiang, 325027, China. Electronic address: .
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Źródło:
International immunopharmacology [Int Immunopharmacol] 2024 Jul 30; Vol. 136, pp. 112372. Date of Electronic Publication: 2024 Jun 07.
Typ publikacji:
Journal Article
MeSH Terms:
Pyroptosis*/drug effects
NF-kappa B*/metabolism
Toll-Like Receptor 4*/metabolism
Hypoxia-Ischemia, Brain*/drug therapy
Hypoxia-Ischemia, Brain*/metabolism
Hypoxia-Ischemia, Brain*/pathology
Signal Transduction*/drug effects
Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/therapeutic use
Rats, Sprague-Dawley*
Animals ; Rats ; PC12 Cells ; Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/therapeutic use ; Male ; Inflammation/drug therapy ; Brain/drug effects ; Brain/pathology ; Brain/metabolism ; Disease Models, Animal ; Animals, Newborn ; Microglia/drug effects ; Microglia/metabolism
Czasopismo naukowe
Tytuł:
Crosstalk between ferroptosis and necroptosis in cerebral ischemia/reperfusion injury and Naotaifang formula exerts neuroprotective effect via HSP90-GCN2-ATF4 pathway.
Autorzy:
Zhou Y; Key Laboratory of Hunan Province for Integrated Traditional Chinese and Western Medicine on Prevention and Treatment of Cardio-Cerebral Diseases, College of Integrated Traditional Chinese and Western Medicine, Hunan University of Chinese Medicine, Changsha, Hunan 410208, China; Department of Scientific Research, Hunan Provincial Hospital of Integrated Traditional Chinese and Western Medicine, Changsha 410006, China.
She R; Key Laboratory of Hunan Province for Integrated Traditional Chinese and Western Medicine on Prevention and Treatment of Cardio-Cerebral Diseases, College of Integrated Traditional Chinese and Western Medicine, Hunan University of Chinese Medicine, Changsha, Hunan 410208, China.
Mei Z; Key Laboratory of Hunan Province for Integrated Traditional Chinese and Western Medicine on Prevention and Treatment of Cardio-Cerebral Diseases, College of Integrated Traditional Chinese and Western Medicine, Hunan University of Chinese Medicine, Changsha, Hunan 410208, China. Electronic address: .
Liu D; Medical School, Hunan University of Chinese Medicine, Changsha, Hunan 410208, China.
Ge J; Key Laboratory of Hunan Province for Integrated Traditional Chinese and Western Medicine on Prevention and Treatment of Cardio-Cerebral Diseases, College of Integrated Traditional Chinese and Western Medicine, Hunan University of Chinese Medicine, Changsha, Hunan 410208, China; Hunan Academy of Chinese Medicine, Changsha, Hunan 410013, China. Electronic address: .
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Źródło:
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2024 Jul 25; Vol. 130, pp. 155399. Date of Electronic Publication: 2024 Feb 01.
Typ publikacji:
Journal Article
MeSH Terms:
Ferroptosis*/drug effects
Reperfusion Injury*/drug therapy
Necroptosis*/drug effects
Neuroprotective Agents*/pharmacology
Rats, Sprague-Dawley*
HSP90 Heat-Shock Proteins*/metabolism
Activating Transcription Factor 4*/metabolism
Animals ; Male ; Rats ; Drugs, Chinese Herbal/pharmacology ; Disease Models, Animal ; Signal Transduction/drug effects ; Infarction, Middle Cerebral Artery/drug therapy ; Brain Ischemia/drug therapy ; Mice
Czasopismo naukowe
Tytuł:
Mechanism of Salvia miltiorrhiza Bunge extract to alleviate Chronic Sleep Deprivation-Induced cognitive dysfunction in rats.
Autorzy:
Yin C; School of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, PR China; Engineering Research Center of TCM Protection Technology and New Product Development for the Elderly Brain Health, Ministry of Education, Hubei University of Chinese Medicine, Wuhan 430065, PR China; Hubei Shizhen Laboratory, Wuhan 430065, PR China.
Zhang M; School of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, PR China; Engineering Research Center of TCM Protection Technology and New Product Development for the Elderly Brain Health, Ministry of Education, Hubei University of Chinese Medicine, Wuhan 430065, PR China; Hubei Shizhen Laboratory, Wuhan 430065, PR China.
Jin S; Hubei Shizhen Laboratory, Wuhan 430065, PR China; School of Basic Medical Sciences, Hubei University of Chinese Medicine, Wuhan 430065, PR China.
Zhou Y; School of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, PR China.
Ding L; School of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, PR China; Engineering Research Center of TCM Protection Technology and New Product Development for the Elderly Brain Health, Ministry of Education, Hubei University of Chinese Medicine, Wuhan 430065, PR China; Hubei Shizhen Laboratory, Wuhan 430065, PR China.
Lv Q; School of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, PR China.
Huang Z; School of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, PR China.
Zhou J; School of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, PR China.
Chen J; School of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, PR China.
Wang P; Engineering Research Center of TCM Protection Technology and New Product Development for the Elderly Brain Health, Ministry of Education, Hubei University of Chinese Medicine, Wuhan 430065, PR China; Hubei Shizhen Laboratory, Wuhan 430065, PR China. Electronic address: .
Zhang S; School of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, PR China. Electronic address: .
You Q; School of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, PR China; Engineering Research Center of TCM Protection Technology and New Product Development for the Elderly Brain Health, Ministry of Education, Hubei University of Chinese Medicine, Wuhan 430065, PR China; Hubei Shizhen Laboratory, Wuhan 430065, PR China. Electronic address: .
Pokaż więcej
Źródło:
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2024 Jul 25; Vol. 130, pp. 155725. Date of Electronic Publication: 2024 May 11.
Typ publikacji:
Journal Article
MeSH Terms:
Salvia miltiorrhiza*/chemistry
Sleep Deprivation*/complications
Sleep Deprivation*/drug therapy
Cognitive Dysfunction*/drug therapy
Rats, Sprague-Dawley*
Drugs, Chinese Herbal*/pharmacology
Animals ; Male ; Rats ; Gastrointestinal Microbiome/drug effects ; Disease Models, Animal ; Hippocampus/drug effects ; Hippocampus/metabolism ; NF-kappa B/metabolism ; Morris Water Maze Test/drug effects ; Maze Learning/drug effects
Czasopismo naukowe
Tytuł:
β-Caryophyllene promotes the survival of random skin flaps by upregulating the PI3K/AKT signaling pathway.
Autorzy:
Deng J; Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, The Second School of Medicine. Wenzhou Medical University, Wenzhou 325000 PR China.
Wang K; Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, The Second School of Medicine. Wenzhou Medical University, Wenzhou 325000 PR China.
Yang J; Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, The Second School of Medicine. Wenzhou Medical University, Wenzhou 325000 PR China.
Wang A; Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, The Second School of Medicine. Wenzhou Medical University, Wenzhou 325000 PR China.
Chen G; Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, The Second School of Medicine. Wenzhou Medical University, Wenzhou 325000 PR China.
Ye M; Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, The Second School of Medicine. Wenzhou Medical University, Wenzhou 325000 PR China.
Chen Q; Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, The Second School of Medicine. Wenzhou Medical University, Wenzhou 325000 PR China.
Lin D; Department of Orthopedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, The Second School of Medicine. Wenzhou Medical University, Wenzhou 325000 PR China. Electronic address: .
Pokaż więcej
Źródło:
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2024 Jul 25; Vol. 130, pp. 155726. Date of Electronic Publication: 2024 May 11.
Typ publikacji:
Journal Article
MeSH Terms:
Proto-Oncogene Proteins c-akt*/metabolism
Signal Transduction*/drug effects
Polycyclic Sesquiterpenes*/pharmacology
Phosphatidylinositol 3-Kinases*/metabolism
Rats, Sprague-Dawley*
Surgical Flaps*
Animals ; Male ; Rats ; Up-Regulation/drug effects ; Skin/drug effects ; Skin/blood supply ; Sesquiterpenes/pharmacology ; Apoptosis/drug effects
Czasopismo naukowe
Tytuł:
Integrated network pharmacology and metabolomics reveal vascular protective effects of Ilex pubescens on thromboangiitis obliterans.
Autorzy:
Chen J; State Key Laboratory of Traditional Chinese Medicine Syndrome, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
Wang Y; State Key Laboratory of Traditional Chinese Medicine Syndrome, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
Chen C; State Key Laboratory of Traditional Chinese Medicine Syndrome, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
Song X; State Key Laboratory of Traditional Chinese Medicine Syndrome, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
Shen X; State Key Laboratory of Traditional Chinese Medicine Syndrome, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
Cao D; Wannan Medical College, Wuhu 241002, China.
Zhao Z; State Key Laboratory of Traditional Chinese Medicine Syndrome, School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou 510006, China. Electronic address: .
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Źródło:
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2024 Jul 25; Vol. 130, pp. 155720. Date of Electronic Publication: 2024 May 11.
Typ publikacji:
Journal Article
MeSH Terms:
Thromboangiitis Obliterans*/drug therapy
Metabolomics*
Network Pharmacology*
Ilex*/chemistry
Plant Extracts*/pharmacology
Plant Extracts*/chemistry
Rats, Sprague-Dawley*
Animals ; Male ; Rats ; Disease Models, Animal ; Femoral Artery/drug effects ; Muscle, Skeletal/drug effects ; Muscle, Skeletal/blood supply ; Muscle, Skeletal/metabolism ; Tandem Mass Spectrometry
Czasopismo naukowe
Tytuł:
Shenling Baizhu powder alleviates non-alcoholic fatty liver disease by modulating autophagy and energy metabolism in high-fat diet-induced rats.
Autorzy:
Pan M; School of Traditional Chinese Medicine, Jinan University, Guangzhou 510632, Guangdong Province, China.
Deng Y; School of Traditional Chinese Medicine, Jinan University, Guangzhou 510632, Guangdong Province, China; Shenzhen Traditional Chinese Medicine Hospital, Shenzhen 518033, Guangdong Province, China.
Qiu Y; School of Traditional Chinese Medicine, Jinan University, Guangzhou 510632, Guangdong Province, China.
Pi D; School of Traditional Chinese Medicine, Jinan University, Guangzhou 510632, Guangdong Province, China.
Zheng C; School of Traditional Chinese Medicine, Jinan University, Guangzhou 510632, Guangdong Province, China.
Liang Z; School of Traditional Chinese Medicine, Jinan University, Guangzhou 510632, Guangdong Province, China.
Zhen J; School of Traditional Chinese Medicine, Jinan University, Guangzhou 510632, Guangdong Province, China.
Fan W; School of Traditional Chinese Medicine, Jinan University, Guangzhou 510632, Guangdong Province, China.
Song Q; School of Traditional Chinese Medicine, Jinan University, Guangzhou 510632, Guangdong Province, China.
Pan J; School of Traditional Chinese Medicine, Jinan University, Guangzhou 510632, Guangdong Province, China.
Li Y; School of Traditional Chinese Medicine, Jinan University, Guangzhou 510632, Guangdong Province, China.
Yan H; Guangzhou Red Cross Hospital, Jinan University, Guangzhou 510240, Guangdong Province, China. Electronic address: .
Yang Q; School of Traditional Chinese Medicine, Jinan University, Guangzhou 510632, Guangdong Province, China. Electronic address: .
Zhang Y; School of Traditional Chinese Medicine, Jinan University, Guangzhou 510632, Guangdong Province, China. Electronic address: .
Pokaż więcej
Źródło:
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2024 Jul 25; Vol. 130, pp. 155712. Date of Electronic Publication: 2024 May 04.
Typ publikacji:
Journal Article
MeSH Terms:
Non-alcoholic Fatty Liver Disease*/drug therapy
Diet, High-Fat*/adverse effects
Drugs, Chinese Herbal*/pharmacology
Drugs, Chinese Herbal*/chemistry
Autophagy*/drug effects
Rats, Sprague-Dawley*
Energy Metabolism*/drug effects
Animals ; Male ; Rats ; Disease Models, Animal ; Powders ; Liver/drug effects ; Liver/metabolism ; Molecular Docking Simulation ; Quercetin/pharmacology ; Quercetin/analogs & derivatives ; Kaempferols/pharmacology ; Oxidative Stress/drug effects
Czasopismo naukowe
Tytuł:
Ginseng total saponin improves red blood cell oxidative stress injury by regulating tyrosine phosphorylation and glycolysis in red blood cells.
Autorzy:
Zhao Y; Northeast Asian Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin, 130117, China.
Cui Y; Northeast Asian Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin, 130117, China.
Ni W; Northeast Asian Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin, 130117, China.
Yu S; Northeast Asian Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin, 130117, China.
Pan D; Northeast Asian Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin, 130117, China.
Liu S; Academic Affairs Office, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin, 130117, China.
Jia Z; School of Pharmacy, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin, 130117, China.
Gao Y; School of Pharmacy, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin, 130117, China.
Zhao D; Northeast Asian Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin, 130117, China.
Liu M; Northeast Asian Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin, 130117, China. Electronic address: .
Wang S; Northeast Asian Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin, 130117, China. Electronic address: .
Pokaż więcej
Źródło:
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2024 Jul 25; Vol. 130, pp. 155785. Date of Electronic Publication: 2024 May 28.
Typ publikacji:
Journal Article
MeSH Terms:
Oxidative Stress*/drug effects
Panax*/chemistry
Erythrocytes*/drug effects
Erythrocytes*/metabolism
Saponins*/pharmacology
Glycolysis*/drug effects
Hydrogen Peroxide*
Tyrosine*/analogs & derivatives
Tyrosine*/pharmacology
Tyrosine*/metabolism
Rats, Sprague-Dawley*
Animals ; Male ; Phosphorylation/drug effects ; Rats ; Hemolysis/drug effects ; Antioxidants/pharmacology ; Anion Exchange Protein 1, Erythrocyte/metabolism ; Apoptosis/drug effects
Czasopismo naukowe
Tytuł:
Kanglexin counters vascular smooth muscle cell dedifferentiation and associated arteriosclerosis through inhibiting PDGFR.
Autorzy:
Yang S; State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Department of Pharmacology (State Key Labratoray -Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin 150081, China.
Zhao Y; State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Department of Pharmacology (State Key Labratoray -Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin 150081, China.
Cao S; State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Department of Pharmacology (State Key Labratoray -Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin 150081, China.
Liu X; State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Department of Pharmacology (State Key Labratoray -Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin 150081, China.
Feng M; State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Department of Pharmacology (State Key Labratoray -Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin 150081, China.
Chen Y; State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Department of Pharmacology (State Key Labratoray -Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin 150081, China.
Ma C; State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Department of Pharmacology (State Key Labratoray -Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin 150081, China.
Zhan T; State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Department of Pharmacology (State Key Labratoray -Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin 150081, China.
Zhang Q; State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Department of Pharmacology (State Key Labratoray -Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin 150081, China.
Jia H; State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Department of Pharmacology (State Key Labratoray -Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin 150081, China.
Zhao Y; State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Department of Pharmacology (State Key Labratoray -Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin 150081, China.
Tong M; State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Department of Pharmacology (State Key Labratoray -Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin 150081, China.
Yu Y; State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Department of Pharmacology (State Key Labratoray -Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin 150081, China.
Liu X; State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Department of Pharmacology (State Key Labratoray -Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin 150081, China.
Yang B; State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Department of Pharmacology (State Key Labratoray -Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin 150081, China; Research Unit of Noninfectious Chronic Diseases in Frigid Zone (2019RU070), Chinese Academy of Medical Sciences, Harbin 150081, China. Electronic address: .
Zhang Y; State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Department of Pharmacology (State Key Labratoray -Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin 150081, China. Electronic address: .
Pokaż więcej
Źródło:
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2024 Jul 25; Vol. 130, pp. 155704. Date of Electronic Publication: 2024 May 01.
Typ publikacji:
Journal Article
MeSH Terms:
Kruppel-Like Factor 4*
Cell Dedifferentiation*/drug effects
Muscle, Smooth, Vascular*/drug effects
Rats, Sprague-Dawley*
Neointima*/drug therapy
Animals ; Male ; Mice ; Rats ; Anthraquinones/pharmacology ; Atherosclerosis/drug therapy ; Myocytes, Smooth Muscle/drug effects ; Arteriosclerosis/drug therapy ; Arteriosclerosis/prevention & control ; Disease Models, Animal ; Signal Transduction/drug effects ; Diet, High-Fat ; Mice, Inbred C57BL ; Kruppel-Like Transcription Factors/metabolism ; Receptors, Platelet-Derived Growth Factor/metabolism ; Molecular Docking Simulation ; Cell Proliferation/drug effects ; Carotid Artery Injuries/drug therapy ; Becaplermin/pharmacology
Czasopismo naukowe
Tytuł:
Podophyllotoxin via SIRT1/PPAR /NF-κB axis induced cardiac injury in rats based on the toxicological evidence chain (TEC) concept.
Autorzy:
Jiang T; Department of Clinical Laboratory, The First Affiliated Hospital, College of Clinical Medicine of Henan University of Science and Technology, Luoyang, 471003, China.
Sun L; College of Chinese Materia Medica and Food Engineering, Shanxi University of Chinese Medicine, Jinzhong 030600, China.
Wang Y; School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
Zhang F; School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
Guo J; Department of Clinical Laboratory, The First Affiliated Hospital, College of Clinical Medicine of Henan University of Science and Technology, Luoyang, 471003, China.
Sun L; Department of Clinical Laboratory, The First Affiliated Hospital, College of Clinical Medicine of Henan University of Science and Technology, Luoyang, 471003, China.
Jiang Y; Department of Clinical Laboratory, The First Affiliated Hospital, College of Clinical Medicine of Henan University of Science and Technology, Luoyang, 471003, China.
Xue J; Department of Clinical Laboratory, The First Affiliated Hospital, College of Clinical Medicine of Henan University of Science and Technology, Luoyang, 471003, China.
Duan J; Department of Clinical Laboratory, The First Affiliated Hospital, College of Clinical Medicine of Henan University of Science and Technology, Luoyang, 471003, China. Electronic address: .
Liu C; Luoyang Key Laboratory of Clinical Multiomics and Translational Medicine, Henan Key Laboratory of Rare Diseases, Endocrinology and Metabolism Center, The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Luoyang, 471003, China. Electronic address: .
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Źródło:
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2024 Jul 25; Vol. 130, pp. 155655. Date of Electronic Publication: 2024 Apr 19.
Typ publikacji:
Journal Article
MeSH Terms:
Sirtuin 1*/metabolism
Rats, Sprague-Dawley*
Podophyllotoxin*/analogs & derivatives
Podophyllotoxin*/pharmacology
NF-kappa B*/metabolism
Animals ; Male ; Rats ; Cardiotoxicity ; Proteomics ; Myocardium/metabolism ; Myocardium/pathology ; Peroxisome Proliferator-Activated Receptors/metabolism ; Heart Injuries/chemically induced ; Heart Injuries/metabolism ; Signal Transduction/drug effects ; Heart/drug effects ; Metabolomics
Czasopismo naukowe
Tytuł:
ShuYu capsule alleviates emotional and physical symptoms of premenstrual dysphoric disorder: Impact on ALLO decline and GABA A receptor δ subunit in the PAG area.
Autorzy:
Geng X; Key Laboratory of Traditional Chinese Medicine Classical Theory, Ministry of Education, Shandong University of Traditional Chinese Medicine, Ji'nan 250355, China; High Level Key Disciplines of Traditional Chinese Medicine, Basic Theory of Traditional Chinese Medicine, National Administration of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Ji'nan 250355, China; Shandong Provincial Engineering Research Center for the Prevention and Treatment of Major Brain Diseases with Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Ji'nan 250355, China.
Wang X; Key Laboratory of Traditional Chinese Medicine Classical Theory, Ministry of Education, Shandong University of Traditional Chinese Medicine, Ji'nan 250355, China; High Level Key Disciplines of Traditional Chinese Medicine, Basic Theory of Traditional Chinese Medicine, National Administration of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Ji'nan 250355, China; Shandong Provincial Engineering Research Center for the Prevention and Treatment of Major Brain Diseases with Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Ji'nan 250355, China.
Liu K; High Level Key Disciplines of Traditional Chinese Medicine, Basic Theory of Traditional Chinese Medicine, National Administration of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Ji'nan 250355, China.
Xing Y; High Level Key Disciplines of Traditional Chinese Medicine, Basic Theory of Traditional Chinese Medicine, National Administration of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Ji'nan 250355, China.
Xu J; High Level Key Disciplines of Traditional Chinese Medicine, Basic Theory of Traditional Chinese Medicine, National Administration of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Ji'nan 250355, China.
Li Z; Key Laboratory of Traditional Chinese Medicine Classical Theory, Ministry of Education, Shandong University of Traditional Chinese Medicine, Ji'nan 250355, China; High Level Key Disciplines of Traditional Chinese Medicine, Basic Theory of Traditional Chinese Medicine, National Administration of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Ji'nan 250355, China; Shandong Provincial Engineering Research Center for the Prevention and Treatment of Major Brain Diseases with Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Ji'nan 250355, China.
Zhang H; Key Laboratory of Traditional Chinese Medicine Classical Theory, Ministry of Education, Shandong University of Traditional Chinese Medicine, Ji'nan 250355, China; High Level Key Disciplines of Traditional Chinese Medicine, Basic Theory of Traditional Chinese Medicine, National Administration of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Ji'nan 250355, China; Shandong Provincial Engineering Research Center for the Prevention and Treatment of Major Brain Diseases with Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Ji'nan 250355, China.
Hu M; Key Laboratory of Traditional Chinese Medicine Classical Theory, Ministry of Education, Shandong University of Traditional Chinese Medicine, Ji'nan 250355, China; High Level Key Disciplines of Traditional Chinese Medicine, Basic Theory of Traditional Chinese Medicine, National Administration of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Ji'nan 250355, China; Shandong Provincial Engineering Research Center for the Prevention and Treatment of Major Brain Diseases with Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Ji'nan 250355, China.
Gao P; Institute of Pharmaceutical Research, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Chen D; Key Laboratory of Traditional Chinese Medicine Classical Theory, Ministry of Education, Shandong University of Traditional Chinese Medicine, Ji'nan 250355, China; Shandong Provincial Engineering Research Center for the Prevention and Treatment of Major Brain Diseases with Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Ji'nan 250355, China.
Liu W; Department of Encephalopathy, The Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Ji'nan 250001, China. Electronic address: Lw_.
Li K; High Level Key Disciplines of Traditional Chinese Medicine, Basic Theory of Traditional Chinese Medicine, National Administration of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Ji'nan 250355, China; Shandong Provincial Engineering Research Center for the Prevention and Treatment of Major Brain Diseases with Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Ji'nan 250355, China. Electronic address: .
Wei S; Key Laboratory of Traditional Chinese Medicine Classical Theory, Ministry of Education, Shandong University of Traditional Chinese Medicine, Ji'nan 250355, China; High Level Key Disciplines of Traditional Chinese Medicine, Basic Theory of Traditional Chinese Medicine, National Administration of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Ji'nan 250355, China; Shandong Provincial Engineering Research Center for the Prevention and Treatment of Major Brain Diseases with Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Ji'nan 250355, China. Electronic address: .
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Źródło:
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2024 Jul 25; Vol. 130, pp. 155549. Date of Electronic Publication: 2024 Mar 19.
Typ publikacji:
Journal Article
MeSH Terms:
Drugs, Chinese Herbal*/pharmacology
Receptors, GABA-A*/metabolism
Pregnanolone*/pharmacology
Premenstrual Dysphoric Disorder*/drug therapy
Rats, Sprague-Dawley*
Animals ; Female ; Rats ; Capsules ; Disease Models, Animal ; Premenstrual Syndrome/drug therapy ; Fluoxetine/pharmacology
Czasopismo naukowe
Tytuł:
Chrysanthemum morifolium attenuates metabolic and alcohol-associated liver disease via gut microbiota and PPARα/γ activation.
Autorzy:
Liu D; Hubei Key Laboratory of Resources and Chemistry of Chinese Medicine, School of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, China; Hubei Shizhen Laboratory, Hubei University of Chinese Medicine, Wuhan 430065, China. Electronic address: .
Zhan J; Hubei Key Laboratory of Resources and Chemistry of Chinese Medicine, School of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, China.
Wang S; Hubei Key Laboratory of Resources and Chemistry of Chinese Medicine, School of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, China.
Chen L; School of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan 430074, China.
Zhu Q; Hubei Key Laboratory of Resources and Chemistry of Chinese Medicine, School of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, China.
Nie R; Hubei Key Laboratory of Resources and Chemistry of Chinese Medicine, School of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, China.
Zhou X; Hubei Key Laboratory of Resources and Chemistry of Chinese Medicine, School of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, China.
Zheng W; Hubei Key Laboratory of Resources and Chemistry of Chinese Medicine, School of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, China.
Luo X; Hubei Key Laboratory of Resources and Chemistry of Chinese Medicine, School of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, China.
Wang B; Key Laboratory of Chinese Medicine Quality Control of State Drug Administration, Hubei Institute for Drug Control, Wuhan 430075, China.
Nie J; Hubei Center for ADR Monitoring, Wuhan 430071, China.
Ye X; Hubei Key Laboratory of Resources and Chemistry of Chinese Medicine, School of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, China; Hubei Shizhen Laboratory, Hubei University of Chinese Medicine, Wuhan 430065, China. Electronic address: .
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Źródło:
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2024 Jul 25; Vol. 130, pp. 155774. Date of Electronic Publication: 2024 May 23.
Typ publikacji:
Journal Article
MeSH Terms:
Chrysanthemum*/chemistry
Gastrointestinal Microbiome*/drug effects
PPAR gamma*/metabolism
PPAR alpha*/metabolism
Liver Diseases, Alcoholic*/drug therapy
Rats, Sprague-Dawley*
Animals ; Male ; Diet, High-Fat/adverse effects ; Rats ; Liver/drug effects ; Liver/metabolism ; Plant Extracts/pharmacology ; Disease Models, Animal ; Signal Transduction/drug effects ; Drugs, Chinese Herbal/pharmacology ; Oxidative Stress/drug effects
Czasopismo naukowe
Tytuł:
Polystyrene nanoplastics exposure causes erectile dysfunction in rats.
Autorzy:
Wang M; Department of Urology, the First Affiliated Hospital of Anhui Medical University, Hefei 230022, China; Institute of Urology, Anhui Medical University, Hefei 230022, China; Anhui Province Key Laboratory of Genitourinary Diseases, Anhui Medical University, Hefei 230022, China.
Dai B; Department of Urology, the First Affiliated Hospital of Anhui Medical University, Hefei 230022, China; Institute of Urology, Anhui Medical University, Hefei 230022, China; Anhui Province Key Laboratory of Genitourinary Diseases, Anhui Medical University, Hefei 230022, China.
Liu Q; Department of Urology, the First Affiliated Hospital of Anhui Medical University, Hefei 230022, China; Institute of Urology, Anhui Medical University, Hefei 230022, China; Anhui Province Key Laboratory of Genitourinary Diseases, Anhui Medical University, Hefei 230022, China.
Wang X; Department of Urology, Southern University of Science and Technology Hospital, Shenzhen 518052, China.
Xiao Y; Department of Urology, Southern University of Science and Technology Hospital, Shenzhen 518052, China.
Zhang G; School of Pharmacy, Shandong Technology Innovation Center of Molecular Targeting and Intelligent Diagnosis and Treatment, Binzhou Medical University, Yantai 264003, China. Electronic address: .
Jiang H; Department of Urology, Peking University First Hospital Institute of Urology, Peking University Andrology Center, Beijing 100034, China. Electronic address: .
Zhang X; Department of Urology, the First Affiliated Hospital of Anhui Medical University, Hefei 230022, China; Institute of Urology, Anhui Medical University, Hefei 230022, China; Anhui Province Key Laboratory of Genitourinary Diseases, Anhui Medical University, Hefei 230022, China. Electronic address: .
Zhang L; Department of Urology, the First Affiliated Hospital of Anhui Medical University, Hefei 230022, China; Institute of Urology, Anhui Medical University, Hefei 230022, China; Anhui Province Key Laboratory of Genitourinary Diseases, Anhui Medical University, Hefei 230022, China; Center for Scientific Research of the First Affiliated Hospital of Anhui Medical University, Hefei 230022, China. Electronic address: .
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Źródło:
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2024 Jul 15; Vol. 280, pp. 116551. Date of Electronic Publication: 2024 Jun 13.
Typ publikacji:
Journal Article
MeSH Terms:
Erectile Dysfunction*/chemically induced
Polystyrenes*/toxicity
Oxidative Stress*/drug effects
Penis*/drug effects
Rats, Sprague-Dawley*
Animals ; Male ; Rats ; Testosterone/blood ; Nanoparticles/toxicity ; Apoptosis/drug effects ; Environmental Pollutants/toxicity
Czasopismo naukowe
Tytuł:
ERβ activation improves nonylphenol-induced depression and neurotransmitter secretion disruption via the TPH2/5-HT pathway.
Autorzy:
Yu J; School of Public Health, Zunyi Medical University, Zunyi, Guizhou 563000, PR China.
Zhang Y; School of Public Health, Zunyi Medical University, Zunyi, Guizhou 563000, PR China.
Yao H; School of Public Health, Zunyi Medical University, Zunyi, Guizhou 563000, PR China.
Zhang Z; Department of Clinical Laboratory, Zunyi Medical and Pharmaceutical College, Zunyi 563006, PR China.
Yang X; School of Public Health, Zunyi Medical University, Zunyi, Guizhou 563000, PR China.
Zhu W; School of Public Health, Zunyi Medical University, Zunyi, Guizhou 563000, PR China.
Xu J; School of Public Health, Zunyi Medical University, Zunyi, Guizhou 563000, PR China. Electronic address: .
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Źródło:
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2024 Jul 15; Vol. 280, pp. 116521. Date of Electronic Publication: 2024 Jun 08.
Typ publikacji:
Journal Article
MeSH Terms:
Tryptophan Hydroxylase*/metabolism
Estrogen Receptor beta*/metabolism
Phenols*/toxicity
Rats, Sprague-Dawley*
Serotonin*/metabolism
Depression*/chemically induced
Depression*/drug therapy
Depression*/metabolism
Animals ; Male ; Rats ; Neurotransmitter Agents/metabolism ; Signal Transduction/drug effects ; Cell Line, Tumor ; Nitriles/toxicity ; Nitriles/pharmacology ; Propionates/toxicity ; Propionates/pharmacology ; Pyrazoles ; Pyrimidines
Czasopismo naukowe
Tytuł:
Pharmacokinetic and oral bioavailability study of schaftoside in rats.
Autorzy:
Lin Y; Wenling Hospital of Traditional Chinese Medicine, Wenling, China.
Wang H; Fuyang Institute for Food and Drug Control, Fuyang, China.
Xu S; Fuyang Institute for Food and Drug Control, Fuyang, China.
Liu C; Faculty of Pharmacy, Naval Medical University, Shanghai, China.
Zhang C; Faculty of Pharmacy, Naval Medical University, Shanghai, China.
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Źródło:
Biomedical chromatography : BMC [Biomed Chromatogr] 2024 Jul; Vol. 38 (7), pp. e5892. Date of Electronic Publication: 2024 May 20.
Typ publikacji:
Journal Article
MeSH Terms:
Biological Availability*
Rats, Sprague-Dawley*
Tandem Mass Spectrometry*/methods
Animals ; Rats ; Male ; Administration, Oral ; Reproducibility of Results ; Linear Models ; Chromatography, Liquid/methods ; Limit of Detection ; Sensitivity and Specificity ; Glycosides/pharmacokinetics ; Glycosides/blood ; Glycosides/chemistry ; Drug Stability
Czasopismo naukowe
Tytuł:
Lymphatic uptake of the lipidated and non-lipidated GLP-1 agonists liraglutide and exenatide is similar in rats.
Autorzy:
Reddiar SB; Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Australia.
Abdallah M; Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Australia.
Styles IK; Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Australia.
Müllertz OO; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Trevaskis NL; Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Australia. Electronic address: .
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Źródło:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V [Eur J Pharm Biopharm] 2024 Jul; Vol. 200, pp. 114339. Date of Electronic Publication: 2024 May 23.
Typ publikacji:
Journal Article
MeSH Terms:
Exenatide*/pharmacokinetics
Exenatide*/administration & dosage
Exenatide*/pharmacology
Liraglutide*/pharmacology
Liraglutide*/pharmacokinetics
Liraglutide*/administration & dosage
Peptides*/pharmacokinetics
Peptides*/administration & dosage
Rats, Sprague-Dawley*
Animals ; Rats ; Male ; Lipids/chemistry ; Half-Life ; Venoms/pharmacokinetics ; Venoms/administration & dosage ; Biological Availability ; Tissue Distribution ; Injections, Subcutaneous ; Lymph/metabolism ; Lymph/drug effects ; Glucagon-Like Peptide-1 Receptor/agonists ; Glucagon-Like Peptide-1 Receptor/metabolism ; Glucagon-Like Peptide 1/pharmacokinetics ; Glucagon-Like Peptide 1/metabolism ; Lymphatic System/metabolism ; Lymphatic System/drug effects ; Hypoglycemic Agents/pharmacokinetics ; Hypoglycemic Agents/administration & dosage ; Hypoglycemic Agents/pharmacology
Czasopismo naukowe
Tytuł:
Serum and urine metabolomics based on UPLC-QTOF/MS reveal the effect and potential mechanism of "schisandra-evodia" herb pair in the treatment of Alzheimer's disease.
Autorzy:
Pang C; College of Medicine, Heilongjiang University of Traditional Chinese Medicine, Harbin, China.
Wang R; College of Medicine, Heilongjiang University of Traditional Chinese Medicine, Harbin, China.
Liu K; Institute of Traditional Chinese Medicine, Heilongjiang University of Traditional Chinese Medicine, Harbin, China.
Yuan X; College of Medicine, Heilongjiang University of Traditional Chinese Medicine, Harbin, China.
Ni J; College of Medicine, Heilongjiang University of Traditional Chinese Medicine, Harbin, China.
Cao Q; Institute of Traditional Chinese Medicine, Heilongjiang University of Traditional Chinese Medicine, Harbin, China.
Chen Y; Institute of Traditional Chinese Medicine, Heilongjiang University of Traditional Chinese Medicine, Harbin, China.
Dong PL; Institute of Traditional Chinese Medicine, Heilongjiang University of Traditional Chinese Medicine, Harbin, China.
Han H; College of Medicine, Heilongjiang University of Traditional Chinese Medicine, Harbin, China.
Pokaż więcej
Źródło:
Biomedical chromatography : BMC [Biomed Chromatogr] 2024 Jul; Vol. 38 (7), pp. e5882. Date of Electronic Publication: 2024 Apr 22.
Typ publikacji:
Journal Article
MeSH Terms:
Alzheimer Disease*/drug therapy
Alzheimer Disease*/metabolism
Metabolomics*/methods
Rats, Sprague-Dawley*
Metabolome*/drug effects
Metabolome*/physiology
Animals ; Rats ; Chromatography, High Pressure Liquid/methods ; Male ; Tandem Mass Spectrometry/methods ; Disease Models, Animal ; Drugs, Chinese Herbal/pharmacology ; Drugs, Chinese Herbal/administration & dosage ; Biomarkers/blood ; Biomarkers/urine ; Hippocampus/metabolism ; Hippocampus/drug effects ; Amyloid beta-Peptides/metabolism
Czasopismo naukowe
Tytuł:
Combination of UPLC-Q-TOF/MS and network pharmacology to reveal the mechanism of Chaihu-jia-Longgu-Muli decoction for treating vertigo with anxiety disorder.
Autorzy:
Wu T; Changchun University of Chinese Medicine, Changchun, Jilin, China.
Dong H; Dizziness Clinic, Jilin Provincial Academy of Chinese Medicine Sciences, Changchun, Jilin, China.
Liu Y; Dizziness Clinic, Jilin Provincial Academy of Chinese Medicine Sciences, Changchun, Jilin, China.
Cao Z; Changchun University of Chinese Medicine, Changchun, Jilin, China.
Sun L; Dizziness Clinic, Jilin Provincial Academy of Chinese Medicine Sciences, Changchun, Jilin, China.
Pokaż więcej
Źródło:
Biomedical chromatography : BMC [Biomed Chromatogr] 2024 Jul; Vol. 38 (7), pp. e5881. Date of Electronic Publication: 2024 May 19.
Typ publikacji:
Journal Article
MeSH Terms:
Drugs, Chinese Herbal*/pharmacology
Drugs, Chinese Herbal*/chemistry
Vertigo*/drug therapy
Network Pharmacology*
Anxiety Disorders*/drug therapy
Rats, Sprague-Dawley*
Animals ; Chromatography, High Pressure Liquid/methods ; Rats ; Male ; Mass Spectrometry/methods ; Protein Interaction Maps/drug effects ; Disease Models, Animal
Czasopismo naukowe
Tytuł:
Novel biomimetic macromolecules system for highly efficient lubrication, ROS scavenging and osteoarthritis treatment.
Autorzy:
Zhao X; State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China; Shandong Laboratory of Yantai Advanced Materials and Green Manufacture, Yantai Zhongke Research Institute of Advanced Materials and Green Chemical Engineering, Yantai 264006, China.
Yang L; State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China. Electronic address: .
Zhang L; Department of Orthopedics, Chinese PLA General Hospital, National Clinical Research Center for Orthopedics, Sports Medicine and Rehabilitation, Beijing 100853, China.
Ji L; Department of Orthopaedic Surgery, Shaanxi Provincial People's Hospital, Xi'an 710068, China.
Ma S; State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China; Shandong Laboratory of Yantai Advanced Materials and Green Manufacture, Yantai Zhongke Research Institute of Advanced Materials and Green Chemical Engineering, Yantai 264006, China. Electronic address: .
Zhou F; State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China.
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Źródło:
Colloids and surfaces. B, Biointerfaces [Colloids Surf B Biointerfaces] 2024 Jul; Vol. 239, pp. 113956. Date of Electronic Publication: 2024 May 08.
Typ publikacji:
Journal Article
MeSH Terms:
Reactive Oxygen Species*/metabolism
Osteoarthritis*/drug therapy
Osteoarthritis*/metabolism
Osteoarthritis*/pathology
Rats, Sprague-Dawley*
Animals ; Rats ; Biomimetic Materials/chemistry ; Biomimetic Materials/pharmacology ; Macromolecular Substances/chemistry ; Macromolecular Substances/pharmacology ; Lubrication ; Male ; Cartilage, Articular/metabolism ; Cartilage, Articular/drug effects ; Cartilage, Articular/pathology ; Free Radical Scavengers/pharmacology ; Free Radical Scavengers/chemistry ; Surface Properties ; Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/chemistry
Czasopismo naukowe

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