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Wyszukujesz frazę ""Rats, Sprague-Dawley"" wg kryterium: Temat


Tytuł:
Cerebrospinal fluid solute transport associated with sensorimotor brain activity in rodents.
Autorzy:
Kim E; Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA.
Van Reet J; Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA.
Yoo SS; Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA. .
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Źródło:
Scientific reports [Sci Rep] 2023 Oct 09; Vol. 13 (1), pp. 17002. Date of Electronic Publication: 2023 Oct 09.
Typ publikacji:
Journal Article
MeSH Terms:
Rodentia*
Brain*/metabolism
Rats ; Animals ; Male ; Rats, Sprague-Dawley ; Homeostasis/physiology ; Biological Transport/physiology ; Cerebrospinal Fluid/metabolism
Czasopismo naukowe
Tytuł:
Non-invasive enhancement of intracortical solute clearance using transcranial focused ultrasound.
Autorzy:
Yoo SS; Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, MA, 02115, Boston, USA. .
Kim E; Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, MA, 02115, Boston, USA.
Kowsari K; Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, MA, 02115, Boston, USA.
Van Reet J; Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, MA, 02115, Boston, USA.
Kim HC; Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, MA, 02115, Boston, USA.; Department of Artificial Intelligence, Kyungpook National University, Daegu, Republic of Korea.
Yoon K; School of Computational Science and Engineering, Yonsei University, Seoul, Republic of Korea.
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Źródło:
Scientific reports [Sci Rep] 2023 Jul 31; Vol. 13 (1), pp. 12339. Date of Electronic Publication: 2023 Jul 31.
Typ publikacji:
Journal Article
MeSH Terms:
Dextrans*/metabolism
Brain*/physiology
Rats ; Animals ; Rats, Sprague-Dawley ; Ovalbumin/metabolism ; Sonication
Czasopismo naukowe
Tytuł:
High affinity of β-amyloid proteins to cerebral capillaries: implications in chronic lead exposure-induced neurotoxicity in rats.
Autorzy:
Liu LL; School of Health Sciences, Purdue University, 550 Stadium Mall Drive, HAMP-1273, West Lafayette, IN, 47907, USA.
Shen X; School of Health Sciences, Purdue University, 550 Stadium Mall Drive, HAMP-1273, West Lafayette, IN, 47907, USA.; School of Public Health, Qingdao University, Qingdao, China.
Gu H; Department of Neurology, Indiana University School of Medicine, Indianapolis, IN, USA.
Zhao G; School of Health Sciences, Purdue University, 550 Stadium Mall Drive, HAMP-1273, West Lafayette, IN, 47907, USA.; Department of Medical Biology, School of Basic Medical Sciences, Hubei University of Chinese Medicine, Wuhan, China.
Du Y; Department of Neurology, Indiana University School of Medicine, Indianapolis, IN, USA.
Zheng W; School of Health Sciences, Purdue University, 550 Stadium Mall Drive, HAMP-1273, West Lafayette, IN, 47907, USA. .
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Źródło:
Fluids and barriers of the CNS [Fluids Barriers CNS] 2023 May 01; Vol. 20 (1), pp. 32. Date of Electronic Publication: 2023 May 01.
Typ publikacji:
Journal Article
MeSH Terms:
Alzheimer Disease*/chemically induced
Alzheimer Disease*/metabolism
Amyloid beta-Peptides*/metabolism
Brain*/metabolism
Lead*/toxicity
Lead*/metabolism
Animals ; Rats ; Capillaries/metabolism ; Low Density Lipoprotein Receptor-Related Protein-1/metabolism ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł:
The new insight into the inflammatory response following focused ultrasound-mediated blood-brain barrier disruption.
Autorzy:
Choi HJ; Medical Device Development Center, Daegu-Gyeongbuk Medical Innovation Foundation (K-MEDI Hubub), 80, Cheombok-Ro, Dong-Gu, Daegu, 41061, Republic of Korea.
Han M; Medical Device Development Center, Daegu-Gyeongbuk Medical Innovation Foundation (K-MEDI Hubub), 80, Cheombok-Ro, Dong-Gu, Daegu, 41061, Republic of Korea.
Seo H; Department of Computer Science, Gyeongsang National University, 501, Jinju-Daero, Jinju, Gyeongsangnam-Do, 52828, Republic of Korea.
Park CY; Medical Device Development Center, Daegu-Gyeongbuk Medical Innovation Foundation (K-MEDI Hubub), 80, Cheombok-Ro, Dong-Gu, Daegu, 41061, Republic of Korea.
Lee EH; Medical Device Development Center, Daegu-Gyeongbuk Medical Innovation Foundation (K-MEDI Hubub), 80, Cheombok-Ro, Dong-Gu, Daegu, 41061, Republic of Korea. .
Park J; College of Future Industry, Department of High-Tech Medical Device, Gachon University, 1342, Seongnam-Daero, Sujeong-Gu, Seongnam, Gyeonggi, 13120, Republic of Korea. .
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Źródło:
Fluids and barriers of the CNS [Fluids Barriers CNS] 2022 Dec 23; Vol. 19 (1), pp. 103. Date of Electronic Publication: 2022 Dec 23.
Typ publikacji:
Journal Article
MeSH Terms:
Blood-Brain Barrier*/diagnostic imaging
Blood-Brain Barrier*/metabolism
Brain*/diagnostic imaging
Brain*/metabolism
Rats ; Mice ; Animals ; Rats, Sprague-Dawley ; Ultrasonography ; Magnetic Resonance Imaging ; Inflammation/metabolism ; Drug Delivery Systems
Czasopismo naukowe
Tytuł:
Cognitive and behavioral effects of whole brain conventional or high dose rate (FLASH) proton irradiation in a neonatal Sprague Dawley rat model.
Autorzy:
Williams MT; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States of America.; Division of Neurology, Cincinnati Children's Research Foundation, Cincinnati, OH, United States of America.; Cincinnati Children's/University of Cincinnati Proton Therapy and Research Center, Cincinnati, OH, United States of America.
Sugimoto C; Division of Neurology, Cincinnati Children's Research Foundation, Cincinnati, OH, United States of America.
Regan SL; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States of America.; Division of Neurology, Cincinnati Children's Research Foundation, Cincinnati, OH, United States of America.
Pitzer EM; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States of America.; Division of Neurology, Cincinnati Children's Research Foundation, Cincinnati, OH, United States of America.
Fritz AL; Division of Neurology, Cincinnati Children's Research Foundation, Cincinnati, OH, United States of America.
Sertorio M; Cincinnati Children's/University of Cincinnati Proton Therapy and Research Center, Cincinnati, OH, United States of America.; Department of Radiation Oncology, University of Cincinnati College of Medicine, Cincinnati, OH, United States of America.
Mascia AE; Cincinnati Children's/University of Cincinnati Proton Therapy and Research Center, Cincinnati, OH, United States of America.; Department of Radiation Oncology, University of Cincinnati College of Medicine, Cincinnati, OH, United States of America.
Vatner RE; Cincinnati Children's/University of Cincinnati Proton Therapy and Research Center, Cincinnati, OH, United States of America.; Department of Radiation Oncology, University of Cincinnati College of Medicine, Cincinnati, OH, United States of America.
Perentesis JP; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States of America.; Cincinnati Children's/University of Cincinnati Proton Therapy and Research Center, Cincinnati, OH, United States of America.; Division of Oncology, Cincinnati Children's Research Foundation, Cincinnati, OH, United States of America.
Vorhees CV; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States of America.; Division of Neurology, Cincinnati Children's Research Foundation, Cincinnati, OH, United States of America.; Cincinnati Children's/University of Cincinnati Proton Therapy and Research Center, Cincinnati, OH, United States of America.
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Źródło:
PloS one [PLoS One] 2022 Sep 16; Vol. 17 (9), pp. e0274007. Date of Electronic Publication: 2022 Sep 16 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Brain*
Protons*
Animals ; Cognition ; Maze Learning ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł:
Labor induction with oxytocin in pregnant rats is not associated with oxidative stress in the fetal brain.
Autorzy:
Giri T; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, USA.
Jiang J; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, USA.; Department of Anesthesiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Xu Z; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, USA.; Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO, 63110, USA.
McCarthy R; Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Halabi CM; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO, USA.
Tycksen E; Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA.
Cahill AG; Department of Women's Health, Dell Medical School, The University of Texas at Austin, Austin, TX, USA.
England SK; Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Palanisamy A; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, USA. .; Department of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, MO, 63110, USA. .
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Źródło:
Scientific reports [Sci Rep] 2022 Feb 24; Vol. 12 (1), pp. 3143. Date of Electronic Publication: 2022 Feb 24.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Labor, Induced*
Brain/*metabolism
Fetus/*metabolism
Oxidative Stress/*drug effects
Oxytocin/*pharmacology
Animals ; Female ; Pregnancy ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł:
Blood-Brain Barrier Disruption Mediated by FFA1 Receptor-Evidence Using Miniscope.
Autorzy:
Lindenau KL; Department of Pharmaceutical Sciences, Jefferson College of Pharmacy, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Barr JL; Department of Neural Sciences and Center for Substance Abuse Research, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA.
Higgins CR; Department of Pharmaceutical Sciences, Jefferson College of Pharmacy, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Sporici KT; Department of Pharmaceutical Sciences, Jefferson College of Pharmacy, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Brailoiu E; Department of Neural Sciences and Center for Substance Abuse Research, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA.
Brailoiu GC; Department of Pharmaceutical Sciences, Jefferson College of Pharmacy, Thomas Jefferson University, Philadelphia, PA 19107, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Feb 18; Vol. 23 (4). Date of Electronic Publication: 2022 Feb 18.
Typ publikacji:
Journal Article
MeSH Terms:
Blood-Brain Barrier/*metabolism
Brain/*metabolism
Receptors, G-Protein-Coupled/*metabolism
Animals ; Capillary Permeability/physiology ; Endothelial Cells/metabolism ; Evans Blue/metabolism ; Fatty Acids, Omega-3/metabolism ; Fluorescein/metabolism ; Male ; Microscopy, Fluorescence/methods ; Permeability ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł:
Enhanced Fear Memories and Altered Brain Glucose Metabolism ( F-FDG-PET) following Subanesthetic Intravenous Ketamine Infusion in Female Sprague-Dawley Rats.
Autorzy:
Radford KD; Daniel K. Inouye Graduate School of Nursing, Uniformed Services University, Bethesda, MD 20814, USA.
Berman RY; Center for the Study of Traumatic Stress, Uniformed Services University, Bethesda, MD 20814, USA.
Jaiswal S; Biomedical Research Imaging Core (BRIC), Department of Radiology and Radiological Sciences, Uniformed Services University, Bethesda, MD 20814, USA.
Kim SY; Program in Neuroscience, Uniformed Services University, Bethesda, MD 20814, USA.
Zhang M; Center for the Study of Traumatic Stress, Uniformed Services University, Bethesda, MD 20814, USA.
Spencer HF; Program in Neuroscience, Uniformed Services University, Bethesda, MD 20814, USA.
Choi KH; Daniel K. Inouye Graduate School of Nursing, Uniformed Services University, Bethesda, MD 20814, USA.; Center for the Study of Traumatic Stress, Uniformed Services University, Bethesda, MD 20814, USA.; Program in Neuroscience, Uniformed Services University, Bethesda, MD 20814, USA.; Department of Psychiatry, F. E. Hébert School of Medicine, Uniformed Services University, Bethesda, MD 20814, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Feb 08; Vol. 23 (3). Date of Electronic Publication: 2022 Feb 08.
Typ publikacji:
Journal Article
MeSH Terms:
Anesthetics, Dissociative/*administration & dosage
Brain/*diagnostic imaging
Conditioning, Psychological/*drug effects
Fear/*drug effects
Glucose/*metabolism
Ketamine/*administration & dosage
Anesthetics, Dissociative/adverse effects ; Animals ; Brain/drug effects ; Brain/metabolism ; Disease Models, Animal ; Dose-Response Relationship, Drug ; Female ; Fluorodeoxyglucose F18/administration & dosage ; Fluorodeoxyglucose F18/metabolism ; Infusions, Intravenous ; Ketamine/adverse effects ; Positron-Emission Tomography ; Rats ; Rats, Sprague-Dawley ; Tomography, X-Ray Computed
Czasopismo naukowe
Tytuł:
Application of a high-resolution in vitro human MDR1-MDCK assay and in vivo studies in preclinical species to improve prediction of CNS drug penetration.
Autorzy:
Jiang L; Vertex Pharmaceuticals, Boston, Massachusetts, USA.
Kumar S; Vertex Pharmaceuticals, Boston, Massachusetts, USA.
Nuechterlein M; Vertex Pharmaceuticals, Boston, Massachusetts, USA.
Reyes M; Vertex Pharmaceuticals, Boston, Massachusetts, USA.
Tran D; Vertex Pharmaceuticals, Boston, Massachusetts, USA.
Cabebe C; Vertex Pharmaceuticals, Boston, Massachusetts, USA.
Chiang P; Vertex Pharmaceuticals, Boston, Massachusetts, USA.
Reynolds J; Vertex Pharmaceuticals, Boston, Massachusetts, USA.
Carrier S; Vertex Pharmaceuticals, Boston, Massachusetts, USA.
Sun Y; Vertex Pharmaceuticals, Boston, Massachusetts, USA.
Eddershaw P; Vertex Pharmaceuticals, Boston, Massachusetts, USA.
Hay T; Vertex Pharmaceuticals, Boston, Massachusetts, USA.
Chen W; Vertex Pharmaceuticals, Boston, Massachusetts, USA.
Feng B; Vertex Pharmaceuticals, Boston, Massachusetts, USA.
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Źródło:
Pharmacology research & perspectives [Pharmacol Res Perspect] 2022 Feb; Vol. 10 (1), pp. e00932.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Blood-Brain Barrier/*metabolism
Brain/*metabolism
Pharmaceutical Preparations/*metabolism
ATP Binding Cassette Transporter, Subfamily B/metabolism ; Animals ; Dogs ; Drug Evaluation, Preclinical/methods ; Humans ; Macaca fascicularis ; Madin Darby Canine Kidney Cells ; Male ; Rats ; Rats, Sprague-Dawley ; Species Specificity ; Time Factors ; Tissue Distribution
Czasopismo naukowe
Tytuł:
The role of neutrophil gelatinase-associated lipocalin and iron homeostasis in object recognition impairment in aged sepsis-survivor rats.
Autorzy:
Nikaido Y; Department of Frailty Research and Prevention, Hirosaki University Graduate School of Medicine, Hirosaki, 0368562, Japan. .; Department of Anesthesiology, Hirosaki University Graduate School of Medicine, Hirosaki, 0368562, Japan. .
Midorikawa Y; Department of Anesthesiology, Hirosaki University Graduate School of Medicine, Hirosaki, 0368562, Japan.
Furukawa T; Department of Neurophysiology, Hirosaki University Graduate School of Medicine, Hirosaki, 0368562, Japan.
Shimoyama S; Department of Neurophysiology, Hirosaki University Graduate School of Medicine, Hirosaki, 0368562, Japan.
Takekawa D; Department of Anesthesiology, Hirosaki University Graduate School of Medicine, Hirosaki, 0368562, Japan.
Kitayama M; Department of Anesthesiology, Hirosaki University Graduate School of Medicine, Hirosaki, 0368562, Japan.
Ueno S; Department of Neurophysiology, Hirosaki University Graduate School of Medicine, Hirosaki, 0368562, Japan.
Kushikata T; Department of Anesthesiology, Hirosaki University Graduate School of Medicine, Hirosaki, 0368562, Japan.
Hirota K; Department of Anesthesiology, Hirosaki University Graduate School of Medicine, Hirosaki, 0368562, Japan.
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Źródło:
Scientific reports [Sci Rep] 2022 Jan 07; Vol. 12 (1), pp. 249. Date of Electronic Publication: 2022 Jan 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Behavior, Animal*/drug effects
Recognition, Psychology*/drug effects
Brain/*enzymology
Cognitive Dysfunction/*enzymology
Iron/*metabolism
Lipocalin-2/*metabolism
Sepsis/*enzymology
Age Factors ; Animals ; Brain/drug effects ; Brain/physiopathology ; Cognitive Dysfunction/physiopathology ; Cognitive Dysfunction/prevention & control ; Cognitive Dysfunction/psychology ; Deferoxamine/pharmacology ; Disease Models, Animal ; Homeostasis ; Male ; Open Field Test ; Rats, Sprague-Dawley ; Sepsis/drug therapy ; Sepsis/physiopathology ; Sepsis/psychology ; Siderophores/pharmacology ; Tumor Necrosis Factor-alpha/metabolism ; Rats
Czasopismo naukowe
Tytuł:
Corticosterone-mediated regulation and functions of miR-218-5p in rat brain.
Autorzy:
Yoshino Y; Department of Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
Roy B; Department of Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
Dwivedi Y; Department of Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham, Birmingham, AL, 35294, USA. .; UAB Mood Disorder Program, Division of Behavioral Neurobiology, Department of Psychiatry and Behavioral Neurobiology, UAB Depression and Suicide Center, University of Alabama at Birmingham, SC711 Sparks Center, 1720 7th Avenue South, Birmingham, AL, USA. .
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Źródło:
Scientific reports [Sci Rep] 2022 Jan 07; Vol. 12 (1), pp. 194. Date of Electronic Publication: 2022 Jan 07.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Brain/*drug effects
Corticosterone/*pharmacology
MicroRNAs/*metabolism
Neurons/*drug effects
Receptors, Glucocorticoid/*agonists
Animals ; Binding Sites ; Brain/metabolism ; Cell Line, Tumor ; Gene Regulatory Networks ; Histone Deacetylase 6/genetics ; Histone Deacetylase 6/metabolism ; Humans ; Male ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; MicroRNAs/genetics ; Neurons/metabolism ; Promoter Regions, Genetic ; Rats, Sprague-Dawley ; Receptors, Glucocorticoid/metabolism ; Signal Transduction ; Time Factors ; Up-Regulation ; Rats
Czasopismo naukowe
Tytuł:
Brain Tissue-Derived Extracellular Vesicle Mediated Therapy in the Neonatal Ischemic Brain.
Autorzy:
Nguyen NP; Molecular Engineering & Sciences Institute, University of Washington, Seattle, WA 98195, USA.
Helmbrecht H; Department of Chemical Engineering, University of Washington, Seattle, WA 98195, USA.
Ye Z; Department of Chemical Engineering, University of Washington, Seattle, WA 98195, USA.; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.
Adebayo T; Department of Biology, University of Washington, Seattle, WA 98195, USA.
Hashi N; Department of Chemical Engineering, University of Washington, Seattle, WA 98195, USA.
Doan MA; Department of Bioengineering, University of Washington, Seattle, WA 98195, USA.
Nance E; Molecular Engineering & Sciences Institute, University of Washington, Seattle, WA 98195, USA.; Department of Chemical Engineering, University of Washington, Seattle, WA 98195, USA.; Department of Bioengineering, University of Washington, Seattle, WA 98195, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Jan 06; Vol. 23 (2). Date of Electronic Publication: 2022 Jan 06.
Typ publikacji:
Journal Article
MeSH Terms:
Brain/*metabolism
Brain/*pathology
Brain Ischemia/*therapy
Extracellular Vesicles/*metabolism
Animals ; Animals, Newborn ; Biomarkers/metabolism ; Cell Shape ; Cell Survival ; Extracellular Vesicles/ultrastructure ; Female ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Rats, Sprague-Dawley ; Rats
Czasopismo naukowe
Tytuł:
Theta oscillations in rat infralimbic cortex are associated with the inhibition of cocaine seeking during extinction.
Autorzy:
Müller Ewald VA; Department of Psychiatry, University of Iowa, Iowa City, Iowa, USA.; Interdisciplinary Neuroscience Program, University of Iowa, Iowa City, Iowa, USA.
Kim J; Interdisciplinary Neuroscience Program, University of Iowa, Iowa City, Iowa, USA.; Department of Psychological and Brain Sciences, University of Iowa, Iowa City, Iowa, USA.
Farley SJ; Interdisciplinary Neuroscience Program, University of Iowa, Iowa City, Iowa, USA.; Department of Psychological and Brain Sciences, University of Iowa, Iowa City, Iowa, USA.
Freeman JH; Interdisciplinary Neuroscience Program, University of Iowa, Iowa City, Iowa, USA.; Department of Psychological and Brain Sciences, University of Iowa, Iowa City, Iowa, USA.; Iowa Neuroscience Institute, University of Iowa, Iowa City, Iowa, USA.
LaLumiere RT; Interdisciplinary Neuroscience Program, University of Iowa, Iowa City, Iowa, USA.; Department of Psychological and Brain Sciences, University of Iowa, Iowa City, Iowa, USA.; Iowa Neuroscience Institute, University of Iowa, Iowa City, Iowa, USA.
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Źródło:
Addiction biology [Addict Biol] 2022 Jan; Vol. 27 (1), pp. e13106. Date of Electronic Publication: 2021 Oct 20.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Brain/*physiology
Cocaine/*pharmacology
Drug-Seeking Behavior/*physiology
Extinction, Psychological/*drug effects
Animals ; Male ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł:
Circulating extracellular vesicles activate the pyroptosis pathway in the brain following ventilation-induced lung injury.
Autorzy:
Chavez L; Department of Pediatrics, University of Miami Miller School of Medicine, 1611 NW 12th Ave, Miami, FL, 33136, USA.
Meguro J; Department of Pediatrics, University of Miami Miller School of Medicine, 1611 NW 12th Ave, Miami, FL, 33136, USA.
Chen S; Department of Pediatrics, University of Miami Miller School of Medicine, 1611 NW 12th Ave, Miami, FL, 33136, USA.
de Paiva VN; Department of Pediatrics, University of Miami Miller School of Medicine, 1611 NW 12th Ave, Miami, FL, 33136, USA.
Zambrano R; Department of Pediatrics, University of Miami Miller School of Medicine, 1611 NW 12th Ave, Miami, FL, 33136, USA.
Eterno JM; Department of Pediatrics, University of Miami Miller School of Medicine, 1611 NW 12th Ave, Miami, FL, 33136, USA.
Kumar R; Department of Pediatrics, University of Miami Miller School of Medicine, 1611 NW 12th Ave, Miami, FL, 33136, USA.
Duncan MR; Department of Pediatrics, University of Miami Miller School of Medicine, 1611 NW 12th Ave, Miami, FL, 33136, USA.
Benny M; Department of Pediatrics, University of Miami Miller School of Medicine, 1611 NW 12th Ave, Miami, FL, 33136, USA.
Young KC; Department of Pediatrics, University of Miami Miller School of Medicine, 1611 NW 12th Ave, Miami, FL, 33136, USA.
Dietrich WD; The Miami Project To Cure Paralysis, Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Brambilla R; The Miami Project To Cure Paralysis, Department of Neurological Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Wu S; Department of Pediatrics, University of Miami Miller School of Medicine, 1611 NW 12th Ave, Miami, FL, 33136, USA.
Schmidt AF; Department of Pediatrics, University of Miami Miller School of Medicine, 1611 NW 12th Ave, Miami, FL, 33136, USA. .
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Źródło:
Journal of neuroinflammation [J Neuroinflammation] 2021 Dec 29; Vol. 18 (1), pp. 310. Date of Electronic Publication: 2021 Dec 29.
Typ publikacji:
Journal Article
MeSH Terms:
Brain/*pathology
Extracellular Vesicles/*pathology
Pyroptosis/*physiology
Ventilator-Induced Lung Injury/*pathology
Animals ; Animals, Newborn ; Caspase 1/blood ; Exosomes/pathology ; Female ; Inflammation Mediators/metabolism ; Interleukin-1beta/blood ; Male ; Phosphate-Binding Proteins/blood ; Pore Forming Cytotoxic Proteins/blood ; Pregnancy ; Rats ; Rats, Sprague-Dawley ; Respiration, Artificial ; Signal Transduction
Czasopismo naukowe
Tytuł:
Maternal N-Acetyl-Cysteine Prevents Neonatal Hypoxia-Induced Brain Injury in a Rat Model.
Autorzy:
Gutziet O; Department of Obstetrics and Gynecology, Rambam Health Care Campus, Haifa 3525433, Israel.; Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 3525408, Israel.
Iluz R; Department of Obstetrics and Gynecology, Rambam Health Care Campus, Haifa 3525433, Israel.; Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 3525408, Israel.
Ben Asher H; Department of Obstetrics and Gynecology, Rambam Health Care Campus, Haifa 3525433, Israel.; Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 3525408, Israel.
Segal L; Department of Obstetrics and Gynecology, Rambam Health Care Campus, Haifa 3525433, Israel.; Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 3525408, Israel.
Ben Zvi D; Department of Obstetrics and Gynecology, Rambam Health Care Campus, Haifa 3525433, Israel.; Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 3525408, Israel.
Ginsberg Y; Department of Obstetrics and Gynecology, Rambam Health Care Campus, Haifa 3525433, Israel.; Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 3525408, Israel.
Khatib N; Department of Obstetrics and Gynecology, Rambam Health Care Campus, Haifa 3525433, Israel.; Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 3525408, Israel.
Zmora O; Department of Pediatric Surgery, Shamir Medical Center, Tzrifin 7073001, Israel.; Sackler School of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.
Ross MG; Department of Obstetrics and Gynecology, Harbor-UCLA Medical Center and The Lundquist Institute, Torrance, CA 92270, USA.
Weiner Z; Department of Obstetrics and Gynecology, Rambam Health Care Campus, Haifa 3525433, Israel.; Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 3525408, Israel.
Beloosesky R; Department of Obstetrics and Gynecology, Rambam Health Care Campus, Haifa 3525433, Israel.; Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 3525408, Israel.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Dec 20; Vol. 22 (24). Date of Electronic Publication: 2021 Dec 20.
Typ publikacji:
Journal Article
MeSH Terms:
Inflammation*
Oxidative Stress*
Acetylcysteine/*metabolism
Asphyxia Neonatorum/*complications
Brain/*metabolism
Hypoxia, Brain/*prevention & control
Animals ; Animals, Newborn ; Antioxidants/metabolism ; Gene Expression Regulation ; Hypoxia, Brain/etiology ; Hypoxia, Brain/metabolism ; In Situ Nick-End Labeling ; Interleukin-6/genetics ; Nitric Oxide Synthase Type I/genetics ; Rats ; Rats, Sprague-Dawley ; Transcription Factor RelA/genetics ; Tumor Necrosis Factor-alpha/genetics
Czasopismo naukowe
Tytuł:
Lithium administered to pregnant, lactating and neonatal rats: entry into developing brain.
Autorzy:
Chiou SY; Department of Biochemistry & Pharmacology, University of Melbourne, Parkville, VIC, 3010, Australia.
Kysenius K; Department of Biochemistry & Pharmacology, University of Melbourne, Parkville, VIC, 3010, Australia.
Huang Y; Department of Biochemistry & Pharmacology, University of Melbourne, Parkville, VIC, 3010, Australia.; Department of Neuroscience, Monash University, 99 Commercial Road, Melbourne, VIC, 3004, Australia.
Habgood MD; Department of Biochemistry & Pharmacology, University of Melbourne, Parkville, VIC, 3010, Australia.; Department of Neuroscience, Monash University, 99 Commercial Road, Melbourne, VIC, 3004, Australia.
Koehn LM; Department of Biochemistry & Pharmacology, University of Melbourne, Parkville, VIC, 3010, Australia.
Qiu F; Department of Biochemistry & Pharmacology, University of Melbourne, Parkville, VIC, 3010, Australia.; Department of Neuroscience, Monash University, 99 Commercial Road, Melbourne, VIC, 3004, Australia.
Crouch PJ; Department of Biochemistry & Pharmacology, University of Melbourne, Parkville, VIC, 3010, Australia.
Varshney S; Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, VIC, 3010, Australia.
Ganio K; Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC, 3000, Australia.
Dziegielewska KM; Department of Biochemistry & Pharmacology, University of Melbourne, Parkville, VIC, 3010, Australia.; Department of Neuroscience, Monash University, 99 Commercial Road, Melbourne, VIC, 3004, Australia.
Saunders NR; Department of Biochemistry & Pharmacology, University of Melbourne, Parkville, VIC, 3010, Australia. .; Department of Neuroscience, Monash University, 99 Commercial Road, Melbourne, VIC, 3004, Australia. .
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Źródło:
Fluids and barriers of the CNS [Fluids Barriers CNS] 2021 Dec 07; Vol. 18 (1), pp. 57. Date of Electronic Publication: 2021 Dec 07.
Typ publikacji:
Journal Article
MeSH Terms:
Blood*
Brain*
Cerebrospinal Fluid*
Maternal-Fetal Exchange*
Milk, Human*
Antimanic Agents/*pharmacokinetics
Lithium Chloride/*pharmacokinetics
Animals ; Animals, Newborn ; Animals, Suckling ; Antimanic Agents/administration & dosage ; Antimanic Agents/blood ; Antimanic Agents/cerebrospinal fluid ; Choroid Plexus ; Embryo, Mammalian ; Female ; Lactation ; Lithium Chloride/administration & dosage ; Lithium Chloride/blood ; Lithium Chloride/cerebrospinal fluid ; Pregnancy ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł:
Neonatal Reserpine Administration Produces Widespread Neuronal Losses and ⍺-Synuclein Inclusions in a Rat Model.
Autorzy:
van Onselen R; Department of Microbiology and Biochemistry, Nelson Mandela University, Port Elizabeth, 6019, South Africa.
Downing TG; Department of Microbiology and Biochemistry, Nelson Mandela University, Port Elizabeth, 6019, South Africa. .
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Źródło:
Neurotoxicity research [Neurotox Res] 2021 Dec; Vol. 39 (6), pp. 1762-1770. Date of Electronic Publication: 2021 Nov 02.
Typ publikacji:
Journal Article
MeSH Terms:
Brain/*drug effects
Inclusion Bodies/*drug effects
Prenatal Exposure Delayed Effects/*chemically induced
Reserpine/*adverse effects
alpha-Synuclein/*metabolism
Animals ; Brain/pathology ; Female ; Inclusion Bodies/pathology ; Neurons/drug effects ; Neurons/pathology ; Pregnancy ; Rats ; Rats, Sprague-Dawley ; Reserpine/administration & dosage
Czasopismo naukowe
Tytuł:
Icariin improves brain function decline in aging rats by enhancing neuronal autophagy through the AMPK/mTOR/ULK1 pathway.
Autorzy:
Zheng J; Medical College of China Three Gorges University, Yichang, P. R. Chinas.
Hu S; Medical College of China Three Gorges University, Yichang, P. R. Chinas.
Wang J; Medical College of China Three Gorges University, Yichang, P. R. Chinas.
Zhang X; Medical College of China Three Gorges University, Yichang, P. R. Chinas.
Yuan D; Medical College of China Three Gorges University, Yichang, P. R. Chinas.
Zhang C; Medical College of China Three Gorges University, Yichang, P. R. Chinas.
Liu C; Medical College of China Three Gorges University, Yichang, P. R. Chinas.
Wang T; Department of Pharmacy, College of Medicine, New Drug Innovation and Development Institute, Wuhan University of Science and Technology, Wuhan, Hubei Province, China.; Hubei Province Key Laboratory of Occupational Hazard Identification and Control, Wuhan University of Science and Technology, Wuhan, Hubei Province, China.
Zhou Z; Medical College of China Three Gorges University, Yichang, P. R. Chinas.
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Źródło:
Pharmaceutical biology [Pharm Biol] 2021 Dec; Vol. 59 (1), pp. 183-191.
Typ publikacji:
Comparative Study; Journal Article
MeSH Terms:
Autophagy/*drug effects
Brain/*drug effects
Flavonoids/*pharmacology
Neurons/*drug effects
AMP-Activated Protein Kinases/metabolism ; Aging/physiology ; Animals ; Autophagy-Related Protein-1 Homolog/metabolism ; Brain/pathology ; Dose-Response Relationship, Drug ; Epimedium/chemistry ; Flavonoids/administration & dosage ; Flavonoids/isolation & purification ; Neurons/pathology ; Rats ; Rats, Sprague-Dawley ; TOR Serine-Threonine Kinases/metabolism
Czasopismo naukowe
Tytuł:
Brain-targeting delivery of MMB4 DMS using carrier-free nanomedicine CRT-MMB4@MDZ.
Autorzy:
Du Y; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Gao J; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Zhang H; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Meng X; Beijing National Laboratory for Molecular Sciences, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China.
Qiu D; Beijing National Laboratory for Molecular Sciences, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China.
Gao X; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Zheng A; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
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Źródło:
Drug delivery [Drug Deliv] 2021 Dec; Vol. 28 (1), pp. 1822-1835.
Typ publikacji:
Journal Article
MeSH Terms:
Antidotes/*pharmacokinetics
Brain/*metabolism
Midazolam/*pharmacokinetics
Nanoparticles/*chemistry
Oximes/*chemistry
Animals ; Antidotes/administration & dosage ; Cell Line ; Dose-Response Relationship, Drug ; Drug Liberation ; Drug Stability ; Male ; Mice ; Mice, Inbred C57BL ; Midazolam/administration & dosage ; Particle Size ; Random Allocation ; Rats ; Rats, Sprague-Dawley ; Receptors, Transferrin/metabolism ; Surface Properties
Czasopismo naukowe
Tytuł:
Choice of anesthesia and data analysis method strongly increases sensitivity of 18F-FDG PET imaging during experimental epileptogenesis.
Autorzy:
Jahreis I; Department of Nuclear Medicine, Hannover Medical School, Hannover, Germany.; Department of Pharmacology, Toxicology and Pharmacy, University of Veterinary Medicine, Hannover, Germany.
Bascuñana P; Department of Nuclear Medicine, Hannover Medical School, Hannover, Germany.
Ross TL; Department of Nuclear Medicine, Hannover Medical School, Hannover, Germany.
Bankstahl JP; Department of Nuclear Medicine, Hannover Medical School, Hannover, Germany.
Bankstahl M; Department of Pharmacology, Toxicology and Pharmacy, University of Veterinary Medicine, Hannover, Germany.
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Źródło:
PloS one [PLoS One] 2021 Nov 24; Vol. 16 (11), pp. e0260482. Date of Electronic Publication: 2021 Nov 24 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Brain/*metabolism
Epilepsy/*metabolism
Glucose/*metabolism
Positron-Emission Tomography/*methods
Anesthesia/methods ; Anesthetics, Inhalation/administration & dosage ; Anesthetics, Inhalation/pharmacology ; Anesthetics, Intravenous/administration & dosage ; Anesthetics, Intravenous/pharmacology ; Animals ; Brain/diagnostic imaging ; Epilepsy/diagnostic imaging ; Female ; Fluorodeoxyglucose F18/metabolism ; Glucose/analysis ; Isoflurane/administration & dosage ; Isoflurane/pharmacology ; Propofol/administration & dosage ; Propofol/pharmacology ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe

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