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Tytuł :
Fatty acid synthase inhibition ameliorates diabetes induced liver injury in rodent experimental model.
Autorzy :
Bedi O; Chitkara College of Pharmacy, Chitkara University, Punjab, India; Department of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala, Punjab, India.
Srivastava N; Department of Dermatology, Venereology and Leprosy, PGIMER, Chandigarh, India.
Parsad D; Department of Dermatology, Venereology and Leprosy, PGIMER, Chandigarh, India.
Krishan P; Department of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala, Punjab, India. Electronic address: .
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Źródło :
European journal of pharmacology [Eur J Pharmacol] 2021 Jun 15; Vol. 901, pp. 174078. Date of Electronic Publication: 2021 Apr 09.
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes Complications/*drug therapy
Enzyme Inhibitors/*therapeutic use
Fatty Acid Synthase, Type I/*antagonists & inhibitors
Liver Diseases/*prevention & control
Animals ; Anthraquinones/therapeutic use ; Antioxidants/metabolism ; Arbutin/therapeutic use ; Blood Glucose/metabolism ; Diabetes Mellitus, Experimental/complications ; Diabetes Mellitus, Experimental/drug therapy ; Diet, High-Fat ; Fatty Acid Synthase, Type I/biosynthesis ; Fatty Acid Synthase, Type I/genetics ; Lipid Metabolism/drug effects ; Lipid Peroxidation/drug effects ; Liver Diseases/etiology ; Male ; Rats ; Rats, Wistar ; Signal Transduction/drug effects ; Stilbenes/therapeutic use
Czasopismo naukowe
Tytuł :
Endogenous opioid and cannabinoid systems modulate the muscle pain: A pharmacological study into the peripheral site.
Autorzy :
Gonçalves WA; Department of Pharmacology, Institute of Biological Sciences, Federal University of Minas Gerais, Brazil.
Ferreira RCM; Department of Pharmacology, Institute of Biological Sciences, Federal University of Minas Gerais, Brazil.
Rezende BM; Department of Morphology, Institute of Biological Sciences, Federal University of Minas Gerais, Brazil.
Mahecha GAB; Department of Morphology, Institute of Biological Sciences, Federal University of Minas Gerais, Brazil.
Gualdron M; Department of Biochemistry and Immunology, Institute of Biological Sciences, Federal University of Minas Gerais, Brazil.
de Macedo FHP; Department of Biochemistry and Immunology, Institute of Biological Sciences, Federal University of Minas Gerais, Brazil.
Duarte IDG; Department of Pharmacology, Institute of Biological Sciences, Federal University of Minas Gerais, Brazil.
Perez AC; Department of Pharmacology, Institute of Biological Sciences, Federal University of Minas Gerais, Brazil.
Machado FS; Department of Biochemistry and Immunology, Institute of Biological Sciences, Federal University of Minas Gerais, Brazil.
Cruz JS; Department of Biochemistry and Immunology, Institute of Biological Sciences, Federal University of Minas Gerais, Brazil.
Romero TRL; Department of Pharmacology, Institute of Biological Sciences, Federal University of Minas Gerais, Brazil. Electronic address: .
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Źródło :
European journal of pharmacology [Eur J Pharmacol] 2021 Jun 15; Vol. 901, pp. 174089. Date of Electronic Publication: 2021 Apr 04.
Typ publikacji :
Journal Article
MeSH Terms :
Myalgia/*drug therapy
Receptors, Cannabinoid/*physiology
Receptors, Opioid/*physiology
Animals ; Arachidonic Acids/antagonists & inhibitors ; Carrageenan ; Cinnamates/pharmacology ; Endocannabinoids/antagonists & inhibitors ; Hyperalgesia/chemically induced ; Hyperalgesia/drug therapy ; Hyperalgesia/psychology ; Male ; Monoacylglycerol Lipases/antagonists & inhibitors ; Morphine Derivatives/pharmacology ; Myalgia/chemically induced ; Myalgia/psychology ; Naloxone/pharmacology ; Naltrexone/analogs & derivatives ; Naltrexone/pharmacology ; Pain Measurement/drug effects ; Polyunsaturated Alkamides/antagonists & inhibitors ; Rats ; Rats, Wistar ; Receptors, Cannabinoid/drug effects ; Receptors, Opioid/drug effects ; Receptors, Opioid, delta/drug effects ; Receptors, Opioid, kappa/drug effects ; Receptors, Opioid, mu/drug effects
Czasopismo naukowe
Tytuł :
Cardiovascular effects of farnesol and its β-cyclodextrin complex in normotensive and hypertensive rats.
Autorzy :
Silva EAP; Department of Physiology, Federal University of Sergipe, São Cristovão, Sergipe, Brazil; Biotechnology Graduate Program - Rede Nordeste de Biotecnologia (RENORBIO), Federal University of Sergipe, São Cristovão, Sergipe, Brazil.
Carvalho JS; Department of Physiology, Federal University of Sergipe, São Cristovão, Sergipe, Brazil.
Dos Santos DM; Department of Physiology, Federal University of Sergipe, São Cristovão, Sergipe, Brazil; Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Sergipe, Brazil.
Oliveira AMS; Department of Pharmacy, Federal University of Sergipe, São Cristovão, Sergipe, Brazil.
de Souza Araújo AA; Department of Pharmacy, Federal University of Sergipe, São Cristovão, Sergipe, Brazil; Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Sergipe, Brazil.
Serafini MR; Department of Pharmacy, Federal University of Sergipe, São Cristovão, Sergipe, Brazil; Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Sergipe, Brazil.
Oliveira Santos LAB; Department of Biology, Federal University of Sergipe, São Cristovão, Sergipe, Brazil.
Batista MVA; Department of Biology, Federal University of Sergipe, São Cristovão, Sergipe, Brazil.
Viana Santos MR; Department of Physiology, Federal University of Sergipe, São Cristovão, Sergipe, Brazil; Biotechnology Graduate Program - Rede Nordeste de Biotecnologia (RENORBIO), Federal University of Sergipe, São Cristovão, Sergipe, Brazil; Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Sergipe, Brazil.
Siqueira Quintans JS; Department of Physiology, Federal University of Sergipe, São Cristovão, Sergipe, Brazil; Biotechnology Graduate Program - Rede Nordeste de Biotecnologia (RENORBIO), Federal University of Sergipe, São Cristovão, Sergipe, Brazil; Department of Health Education, Federal University of Sergipe, Lagarto, Sergipe, Brazil.
Quintans-Júnior LJ; Department of Physiology, Federal University of Sergipe, São Cristovão, Sergipe, Brazil; Biotechnology Graduate Program - Rede Nordeste de Biotecnologia (RENORBIO), Federal University of Sergipe, São Cristovão, Sergipe, Brazil; Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Sergipe, Brazil.
Barreto AS; Department of Health Education, Federal University of Sergipe, Lagarto, Sergipe, Brazil; Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Sergipe, Brazil. Electronic address: .
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Źródło :
European journal of pharmacology [Eur J Pharmacol] 2021 Jun 15; Vol. 901, pp. 174060. Date of Electronic Publication: 2021 Apr 02.
Typ publikacji :
Journal Article
MeSH Terms :
Cardiovascular Agents/*pharmacology
Farnesol/*pharmacology
Hypertension/*drug therapy
beta-Cyclodextrins/*pharmacology
Animals ; Arterial Pressure/drug effects ; Blood Pressure/drug effects ; Bradycardia/drug therapy ; Dose-Response Relationship, Drug ; Enzyme Inhibitors/pharmacology ; Heart Rate/drug effects ; Male ; Molecular Docking Simulation ; NG-Nitroarginine Methyl Ester/pharmacology ; Nitric Oxide Synthase/antagonists & inhibitors ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Xanthenone, ACE2 activator, counteracted gentamicin-induced nephrotoxicity in rats: Impact on oxidative stress and ACE2/Ang-(1-7) signaling.
Autorzy :
Abdel-Fattah MM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Beni-Suef University, Beni-Suef 62514, Egypt. Electronic address: .
Elgendy ANAM; Department of Pharmacology, Faculty of Veterinary Medicine, Beni-Suef University, Beni-Suef, Egypt.
Mohamed WR; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Beni-Suef University, Beni-Suef 62514, Egypt.
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Źródło :
Life sciences [Life Sci] 2021 Jun 15; Vol. 275, pp. 119387. Date of Electronic Publication: 2021 Mar 24.
Typ publikacji :
Journal Article
MeSH Terms :
Acute Kidney Injury/*chemically induced
Angiotensin I/*metabolism
Angiotensin-Converting Enzyme 2/*drug effects
Gentamicins/*toxicity
Oxidative Stress/*drug effects
Peptide Fragments/*metabolism
Signal Transduction/*drug effects
Xanthones/*pharmacology
Acute Kidney Injury/prevention & control ; Angiotensin-Converting Enzyme 2/metabolism ; Animals ; Blotting, Western ; Interleukins/metabolism ; Male ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
The efficacy of bone marrow-derived mesenchymal stem cells and/or erythropoietin in ameliorating kidney damage in gamma irradiated rats: Role of non-hematopoietic erythropoietin anti-apoptotic signaling.
Autorzy :
Asker ME; Department of Biochemistry, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt.
Ali SI; Department of Biochemistry, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt.
Mohamed SH; Drug Radiation Research Department, National Center for Radiation Research and Technology, Atomic Energy Authority, PO Box 29, Nasr City, Cairo, Egypt.
Abdelaleem RMA; Drug Radiation Research Department, National Center for Radiation Research and Technology, Atomic Energy Authority, PO Box 29, Nasr City, Cairo, Egypt.
Younis NN; Department of Biochemistry, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Jun 15; Vol. 275, pp. 119388. Date of Electronic Publication: 2021 Mar 24.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis*/drug effects
Mesenchymal Stem Cell Transplantation*
Erythropoietin/*therapeutic use
Kidney/*radiation effects
Radiation Injuries, Experimental/*therapy
Animals ; Combined Modality Therapy ; Creatinine/blood ; Gamma Rays/adverse effects ; Male ; Rats ; Rats, Wistar ; Urea/blood
Czasopismo naukowe
Tytuł :
Cardioprotective effects of severe calorie restriction from birth in adult ovariectomized rats.
Autorzy :
Rodrigues CM; Programa de Pós-graduação Multicêntrico em Ciências Fisiológicas, Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil.
Domingues TE; Programa de Pós-graduação Multicêntrico em Ciências Fisiológicas, Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil.
de Sousa Santos C; Programa de Pós-graduação Multicêntrico em Ciências Fisiológicas, Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil.
Costa-Pereira LV; Programa de Pós-graduação Multicêntrico em Ciências Fisiológicas, Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil.
Mendes BF; Programa de Pós-graduação Multicêntrico em Ciências Fisiológicas, Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil.
Dos Santos JM; Programa de Pós-graduação Multicêntrico em Ciências Fisiológicas, Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil.
Costa KB; Programa de Pós-graduação Multicêntrico em Ciências Fisiológicas, Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil.
Silva G; Programa de Pós-graduação Multicêntrico em Ciências Fisiológicas, Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil.
Cantuária VL; Programa de Pós-graduação Multicêntrico em Ciências Fisiológicas, Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil; Faculdade de Medicina, UFVJM, Diamantina, Brazil.
Rocha-Vieira E; Programa de Pós-graduação Multicêntrico em Ciências Fisiológicas, Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil; Faculdade de Medicina, UFVJM, Diamantina, Brazil; Programa de Pós-graduação em Ciências da Saúde, UFVJM, Diamantina, Brazil.
Dias-Peixoto MF; Programa de Pós-graduação Multicêntrico em Ciências Fisiológicas, Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil; Programa de Pós-graduação em Ciências da Saúde, UFVJM, Diamantina, Brazil; Faculdade de Ciências Biológicas e da Saúde, UFVJM, Diamantina, Brazil.
Honorato-Sampaio K; Programa de Pós-graduação Multicêntrico em Ciências Fisiológicas, Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil; Faculdade de Medicina, UFVJM, Diamantina, Brazil; Programa de Pós-graduação em Ciências da Saúde, UFVJM, Diamantina, Brazil. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Jun 15; Vol. 275, pp. 119411. Date of Electronic Publication: 2021 Mar 24.
Typ publikacji :
Journal Article
MeSH Terms :
Caloric Restriction*
Ovariectomy*
Cardiovascular Diseases/*prevention & control
Animals ; Blood Pressure ; Blotting, Western ; Female ; Heart Rate ; Oxidation-Reduction ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Autophagy-lysosomal signaling responses to heat stress in tenotomy-induced rat skeletal muscle atrophy.
Autorzy :
Hirunsai M; Department of Biopharmacy, Faculty of Pharmacy, Srinakharinwirot University, Nakhon Nayok 26120, Thailand. Electronic address: .
Srikuea R; Department of Physiology, Faculty of Science, Mahidol University, Bangkok 10400, Thailand.
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Źródło :
Life sciences [Life Sci] 2021 Jun 15; Vol. 275, pp. 119352. Date of Electronic Publication: 2021 Mar 23.
Typ publikacji :
Journal Article
MeSH Terms :
Autophagy/*physiology
Heat-Shock Response/*physiology
Lysosomes/*physiology
Muscular Atrophy/*physiopathology
Achilles Tendon/surgery ; Animals ; Electrophoresis, Polyacrylamide Gel ; Humans ; Lysosomes/metabolism ; Male ; Muscular Atrophy/metabolism ; Myosin Heavy Chains/metabolism ; Rats ; Rats, Wistar ; Signal Transduction ; Tenotomy/adverse effects
Czasopismo naukowe
Tytuł :
Inhibition of thioredoxin-interacting protein and inflammasome assembly using verapamil mitigates diabetic retinopathy and pancreatic injury.
Autorzy :
Eissa LD; Ministry of Health, Port-Said, Egypt.
Ghobashy WA; Department of Ophthalmology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.
El-Azab MF; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Suez Canal University, Ismailia, Egypt. Electronic address: .
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Źródło :
European journal of pharmacology [Eur J Pharmacol] 2021 Jun 15; Vol. 901, pp. 174061. Date of Electronic Publication: 2021 Mar 22.
Typ publikacji :
Journal Article
MeSH Terms :
Calcium Channel Blockers/*therapeutic use
Cell Cycle Proteins/*antagonists & inhibitors
Diabetic Retinopathy/*drug therapy
Inflammasomes/*drug effects
Pancreatic Diseases/*drug therapy
Verapamil/*therapeutic use
Angiogenesis Inhibitors/pharmacology ; Animals ; Blood Glucose/analysis ; Blood Glucose/metabolism ; Diabetes Mellitus, Experimental/drug therapy ; Diabetes Mellitus, Type 1/chemically induced ; Diabetes Mellitus, Type 1/drug therapy ; Rats ; Rats, Wistar ; Retinal Ganglion Cells/drug effects ; Thioredoxin-Disulfide Reductase/antagonists & inhibitors ; Weight Loss/drug effects
Czasopismo naukowe
Tytuł :
Mechanistic insights into the protective effects of chlorogenic acid against indomethacin-induced gastric ulcer in rats: Modulation of the cross talk between autophagy and apoptosis signaling.
Autorzy :
Ahmed MAE; Department of Pharmacology and Toxicology, Faculty of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology (MUST), 6th of October City, Giza, Egypt. Electronic address: .
Mohanad M; Department of Biochemistry, Faculty of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology (MUST), 6th of October City, Giza, Egypt.
Ahmed AAE; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Helwan University, Ein Helwan, Cairo, Egypt.
Aboulhoda BE; Department of Anatomy and Embryology, Faculty of Medicine, Cairo University, Cairo, Egypt.
El-Awdan SA; Department of Pharmacology, National Research Centre, Dokki, Giza, Egypt.
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Źródło :
Life sciences [Life Sci] 2021 Jun 15; Vol. 275, pp. 119370. Date of Electronic Publication: 2021 Mar 17.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis/*drug effects
Autophagy/*drug effects
Chlorogenic Acid/*therapeutic use
Indomethacin/*adverse effects
Stomach Ulcer/*chemically induced
Animals ; Gastric Mucosa/drug effects ; Gastric Mucosa/pathology ; Indomethacin/antagonists & inhibitors ; Male ; Proto-Oncogene Proteins c-akt/metabolism ; Rats ; Rats, Wistar ; Signal Transduction/drug effects ; Stomach Ulcer/pathology ; Stomach Ulcer/prevention & control ; TOR Serine-Threonine Kinases/metabolism
Czasopismo naukowe
Tytuł :
Targeting KEAP1/Nrf2, AKT, and PPAR-γ signals as a potential protective mechanism of diosmin against gentamicin-induced nephrotoxicity.
Autorzy :
Ali FEM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Al-Azhar University, Assiut 71524, Egypt. Electronic address: .
Sayed AM; Biochemistry Laboratory, Chemistry Department, Faculty of Science, Assiut University, Egypt.
El-Bahrawy AH; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Al-Azhar University, Assiut 71524, Egypt.
Omar ZMM; Department of Pharmacology, College of Medicine, Al-Azhar University, Assiut 71524, Egypt.
Hassanein EHM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Al-Azhar University, Assiut 71524, Egypt.
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Źródło :
Life sciences [Life Sci] 2021 Jun 15; Vol. 275, pp. 119349. Date of Electronic Publication: 2021 Mar 17.
Typ publikacji :
Journal Article
MeSH Terms :
Acute Kidney Injury/*chemically induced
Diosmin/*therapeutic use
Gentamicins/*toxicity
Kelch-Like ECH-Associated Protein 1/*metabolism
Oncogene Protein v-akt/*metabolism
PPAR gamma/*metabolism
Signal Transduction/*drug effects
Acute Kidney Injury/pathology ; Acute Kidney Injury/prevention & control ; Animals ; Blotting, Western ; Creatinine/blood ; Diosmin/pharmacology ; Kidney/drug effects ; Kidney/pathology ; Male ; NF-E2-Related Factor 2/metabolism ; Rats ; Rats, Wistar ; Urea/blood ; Uric Acid/blood
Czasopismo naukowe
Tytuł :
Resistance exercise training ameliorates chronic kidney disease outcomes in a 5/6 nephrectomy model.
Autorzy :
Saud A; Departamento de Medicina, Disciplina de Nefrologia, Escola Paulista de Medicina, Universidade Federal de São Paulo, SP, Brazil.
Luiz RS; Departamento de Medicina, Disciplina de Nefrologia, Escola Paulista de Medicina, Universidade Federal de São Paulo, SP, Brazil.
Leite APO; Departamento de Medicina, Disciplina de Nefrologia, Escola Paulista de Medicina, Universidade Federal de São Paulo, SP, Brazil; Tulane University, Department of Physiology & Medicine, New Orleans, LA, United States.
Muller CR; Department of Bioengineering, University of California San Diego, La Jolla, CA, United States.
Visona I; Departamento de Patologia, Escola Paulista de Medicina, Universidade Federal de São Paulo, SP, Brazil.
Reinecke N; Departamento de Medicina, Disciplina de Nefrologia, Escola Paulista de Medicina, Universidade Federal de São Paulo, SP, Brazil.
Silva WH; Departamento de Medicina, Disciplina de Nefrologia, Escola Paulista de Medicina, Universidade Federal de São Paulo, SP, Brazil.
Gloria MA; Departamento de Medicina, Disciplina de Nefrologia, Escola Paulista de Medicina, Universidade Federal de São Paulo, SP, Brazil.
Razvickas CV; Departamento de Medicina, Disciplina de Nefrologia, Escola Paulista de Medicina, Universidade Federal de São Paulo, SP, Brazil.
Casarini DE; Departamento de Medicina, Disciplina de Nefrologia, Escola Paulista de Medicina, Universidade Federal de São Paulo, SP, Brazil. Electronic address: .
Schor N; Departamento de Medicina, Disciplina de Nefrologia, Escola Paulista de Medicina, Universidade Federal de São Paulo, SP, Brazil.
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Źródło :
Life sciences [Life Sci] 2021 Jun 15; Vol. 275, pp. 119362. Date of Electronic Publication: 2021 Mar 16.
Typ publikacji :
Journal Article
MeSH Terms :
Resistance Training*
Renal Insufficiency, Chronic/*therapy
Animals ; Creatine/analogs & derivatives ; Creatine/blood ; Creatine/urine ; Disease Models, Animal ; Male ; Nephrectomy ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
The soluble guanylate cyclase stimulator, 1-nitro-2-phenylethane, reverses monocrotaline-induced pulmonary arterial hypertension in rats.
Autorzy :
Gonzaga-Costa K; Department of Physiology and Pharmacology, School of Medicine, Federal University of Ceará, CE, Brazil.
Roque CR; Department of Physiology and Pharmacology, School of Medicine, Federal University of Ceará, CE, Brazil.
Vasconcelos-Silva AA; Department of Physiology and Pharmacology, School of Medicine, Federal University of Ceará, CE, Brazil.
Sousa-Brito HL; Department of Physiology and Pharmacology, School of Medicine, Federal University of Ceará, CE, Brazil.
Martins CS; Department of Morphology, Lab Nempi, School of Medicine, Federal University of Ceará, CE, Brazil.
Caetano-Souza MM; VETER, Veterinary Diagnostic Center, Fortaleza, CE, Brazil.
Duarte GP; Department of Physiology and Pharmacology, Federal University of Pernambuco, Recife, PE, Brazil.
da Silva JKR; Faculty of Biotechology, Institute of Biological Sciences, federal University of Pará, Belém, PA, Brazil.
Borges RS; Department of Pharmacy, Federal University of Pará, Belém, PA, Brazil.
Dos Santos AA; Department of Physiology and Pharmacology, School of Medicine, Federal University of Ceará, CE, Brazil.
Magalhães PJC; Department of Physiology and Pharmacology, School of Medicine, Federal University of Ceará, CE, Brazil.
Lahlou S; Department of Physiology and Pharmacology, School of Medicine, Federal University of Ceará, CE, Brazil. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Jun 15; Vol. 275, pp. 119334. Date of Electronic Publication: 2021 Mar 09.
Typ publikacji :
Journal Article
MeSH Terms :
Benzene Derivatives/*pharmacology
Pulmonary Arterial Hypertension/*drug therapy
Animals ; Echocardiography ; Endothelium, Vascular/drug effects ; Hemodynamics/drug effects ; Male ; Monocrotaline/antagonists & inhibitors ; Monocrotaline/pharmacology ; Pulmonary Arterial Hypertension/chemically induced ; Pulmonary Arterial Hypertension/diagnostic imaging ; Pulmonary Artery/drug effects ; Rats ; Rats, Wistar ; Soluble Guanylyl Cyclase/drug effects ; Vascular Remodeling/drug effects
Czasopismo naukowe
Tytuł :
Histological evaluation of capsules formed by texturized silicone implants with and without polyester mesh coverage (Parietex®). A study on female rats.
Autorzy :
Berger R; Fellow Master degree. Postgraduate Program in Principles of Surgery - Mackenzie Evangelical School of Medicine - Curitiba (PR), Brazil.
Ribas Filho JM; PhD, Associate Professor. Postgraduate Program in Principles of Surgery - Mackenzie Evangelical School of Medicine - Curitiba (PR), Brazil.
Malafaia O; PhD, Full Professor. Postgraduate Program in Principles of Surgery - Mackenzie Evangelical School of Medicine - Curitiba (PR), Brazil.
Nassif PAN; PhD, Associate Professor. Postgraduate Program in Principles of Surgery - Mackenzie Evangelical School of Medicine - Curitiba (PR), Brazil.
Silva EN; PhD. General Surgery - Universidade Estadual de Ponta Grossa - Ponta Grossa (PR), Brazil.
Silva ABDD; MD. Plastic Surgery Department - Hospital Erasto Gaertner - Curitiba (PR), Brazil.
Takejima M; MD. Postgraduate Program in Plastic Surgery - Hospital Universitário Evangélico Mackenzie, and Instituto de Pesquisa Médica - Curitiba (PR), Brazil.
Souza MA; Graduate Student. Universidade Estadual de Ponta Grossa - Ponta Grossa (PR), Brazil.
Paula PH; Graduate Student. Universidade Estadual de Ponta Grossa - Ponta Grossa (PR), Brazil.
Montemor Netto MR; MSc. Clinical Surgery - Universidade Federal do Paraná - Curitiba (PR). Assistant Professor. Anatomical Pathology - Universidade Estadual de Ponta Grossa - Ponta Grossa (PR). Head. Department of Anatomical Pathology - Santa Casa de Misericórdia - Ponta Grossa (PR), Brazil.
Noronha L; PhD. School of Medicine - Pontifícia Universidade Católica do Paraná - Curitiba (PR), Brazil.
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Źródło :
Acta cirurgica brasileira [Acta Cir Bras] 2021 Jun 14; Vol. 36 (5), pp. e360505. Date of Electronic Publication: 2021 Jun 14 (Print Publication: 2021).
Typ publikacji :
Journal Article
MeSH Terms :
Breast Implants*/adverse effects
Silicones*
Animals ; Capsules ; Collagen ; Female ; Polyesters ; Rats ; Rats, Wistar ; Surgical Mesh/adverse effects
Czasopismo naukowe
Tytuł :
BETWEEN PROLENE®, ULTRAPRO® AND BARD SOFT® MESHES WHICH PRESENTS THE BEST PERFORMANCE IN THE REPAIR OF THE ABDOMINAL WALL?
Autorzy :
Utrabo CAL; School of Medicine, State University of Ponta Grossa, Ponta Grossa, PR, Brazil.
Czeczko NG; Post-Graduate Program in Principles of Surgery, Evangelical Mackenzie Faculty of Paraná, Curitiba, PR, Brazil.
Busato CR; School of Medicine, State University of Ponta Grossa, Ponta Grossa, PR, Brazil.
Montemór-Netto MR; Post-Graduate Program in Principles of Surgery, Evangelical Mackenzie Faculty of Paraná, Curitiba, PR, Brazil.
Lipinski L; Post-Graduate Program in Principles of Surgery, Evangelical Mackenzie Faculty of Paraná, Curitiba, PR, Brazil.
Malafaia O; Post-Graduate Program in Principles of Surgery, Evangelical Mackenzie Faculty of Paraná, Curitiba, PR, Brazil.
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Źródło :
Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery [Arq Bras Cir Dig] 2021 Jun 11; Vol. 34 (1), pp. e1577. Date of Electronic Publication: 2021 Jun 11 (Print Publication: 2021).
Typ publikacji :
Journal Article
MeSH Terms :
Abdominal Wall*/surgery
Polypropylenes*
Animals ; Peritoneum ; Rats ; Rats, Wistar ; Surgical Mesh
Czasopismo naukowe
Tytuł :
[Effects of duodenal ligation on gastroesophageal reflux and bleomycin-induced pulmonary fibrosis in rats].
Autorzy :
Li M; Department of Respiratory and Critical Care Medicine, People's Hospital of Henan University, Zhengzhou 450003, China.
Zhang JJ; Department of Respiratory and Critical Care Medicine, People's Hospital of Henan University, Zhengzhou 450003, China.
Li XN; Department of Respiratory and Critical Care Medicine, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, People's Hospital of Henan University, Zhengzhou 450003, China.
Zhang J; Department of Respiratory and Critical Care Medicine, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, People's Hospital of Henan University, Zhengzhou 450003, China.
An YX; Department of Respiratory and Critical Care Medicine, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, People's Hospital of Henan University, Zhengzhou 450003, China.
Zhang QC; Department of Respiratory and Critical Care Medicine, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, People's Hospital of Henan University, Zhengzhou 450003, China.
Li HX; Department of Respiratory and Critical Care Medicine, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, People's Hospital of Henan University, Zhengzhou 450003, China.
Liu LF; Department of Respiratory and Critical Care Medicine, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, People's Hospital of Henan University, Zhengzhou 450003, China.
Guo QY; Department of Gastroenterology, Zhengzhou University People's Hospital, Zhengzhou 450003, China.
Wang Z; Department of Respiratory and Critical Care Medicine, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, People's Hospital of Henan University, Zhengzhou 450003, China.
Zhang XJ; Department of Respiratory and Critical Care Medicine, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, People's Hospital of Henan University, Zhengzhou 450003, China.
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Źródło :
Zhonghua yi xue za zhi [Zhonghua Yi Xue Za Zhi] 2021 Jun 08; Vol. 101 (21), pp. 1598-1605.
Typ publikacji :
Journal Article
MeSH Terms :
Gastroesophageal Reflux*
Pulmonary Fibrosis*/chemically induced
Animals ; Bleomycin ; Bronchoalveolar Lavage Fluid ; Duodenum ; Lung ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Therapeutic potential of quercetin in an animal model of PCOS: Possible involvement of AMPK/SIRT-1 axis.
Autorzy :
Mihanfar A; Department of Clinical Biochemistry, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran.
Nouri M; Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; Department of Reproductive Biology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences Tabriz, Iran; Stem Cell and Regenerative Medicine Institute, Tabriz University of Medical Sciences, Tabriz, Iran.
Roshangar L; Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Khadem-Ansari MH; Department of Clinical Biochemistry, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran. Electronic address: .
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Źródło :
European journal of pharmacology [Eur J Pharmacol] 2021 Jun 05; Vol. 900, pp. 174062. Date of Electronic Publication: 2021 Mar 31.
Typ publikacji :
Journal Article
MeSH Terms :
AMP-Activated Protein Kinases/*drug effects
Polycystic Ovary Syndrome/*drug therapy
Quercetin/*therapeutic use
Sirtuin 1/*drug effects
Adiponectin/metabolism ; Animals ; Estrous Cycle/drug effects ; Female ; Hormones/blood ; Insulin Resistance ; Letrozole ; Lipid Metabolism/drug effects ; Nicotinamide Phosphoribosyltransferase/metabolism ; Polycystic Ovary Syndrome/chemically induced ; Polycystic Ovary Syndrome/pathology ; Rats ; Rats, Wistar ; Resistin/metabolism
Czasopismo naukowe
Tytuł :
Neuroprotective role of camphor against ciprofloxacin induced depression in rats: modulation of Nrf-2 and TLR4.
Autorzy :
Salama A; Department of Pharmacology, National Research Centre, Cairo, Egypt.
Mahmoud HA; Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt.
Kandeil MA; Department of Biochemistry, Faculty of Veterinary medicine, Beni-Suef University, Beni Suef, Egypt.
Khalaf MM; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Beni-Suef University, Beni Suef, Egypt.
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Źródło :
Immunopharmacology and immunotoxicology [Immunopharmacol Immunotoxicol] 2021 Jun; Vol. 43 (3), pp. 309-318. Date of Electronic Publication: 2021 May 25.
Typ publikacji :
Journal Article; Video-Audio Media
MeSH Terms :
Depression*/chemically induced
Depression*/drug therapy
Depression*/metabolism
Camphor/*pharmacology
Ciprofloxacin/*adverse effects
NF-E2-Related Factor 2/*metabolism
Neuroprotective Agents/*pharmacology
Toll-Like Receptor 4/*metabolism
Animals ; COVID-19/drug therapy ; COVID-19/metabolism ; COVID-19/pathology ; Ciprofloxacin/pharmacology ; Male ; Rats ; Rats, Wistar ; SARS-CoV-2/metabolism
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
Repeated endosulfan exposure induces changes in neurochemicals, decreases ATPase transmembrane ionic-pumps, and increased oxidative/nitrosative stress in the brains of rats: Reversal by quercetin.
Autorzy :
Oyovwi MO; Department of Basic Medical Sciences, Achievers University, Owo, Ondo State, Nigeria.
Ben-Azu B; Department of Pharmacology and Therapeutics, Faculty of Basic Medical Science, College of Health Sciences, Delta State University, Abraka, Delta State, Nigeria. Electronic address: .
Tesi EP; Department of Science Laboratory Technology, Delta State Polytechnic, Ogwashi-Uku, Delta State, Nigeria.
Oyeleke AA; Department of Basic Medical Sciences, Achievers University, Owo, Ondo State, Nigeria.
Uruaka CI; Department of Pharmacology and Therapeutics, Faculty of Basic Medical Science, Rivers State University, Port Harcourt, Rivers State, Nigeria.
Rotu RA; Department of Industrial safety and Environmental Management, School of Maritime Technology, Burutu, Delta State, Nigeria.
Aya-Ebi EO; Neuropharmacology Unit, Department of Pharmacology and Therapeutics, College of Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria.
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Źródło :
Pesticide biochemistry and physiology [Pestic Biochem Physiol] 2021 Jun; Vol. 175, pp. 104833. Date of Electronic Publication: 2021 Mar 26.
Typ publikacji :
Journal Article
MeSH Terms :
Nitrosative Stress*
Quercetin*/pharmacology
Adenosine Triphosphatases/metabolism ; Animals ; Antioxidants ; Brain/metabolism ; Catalase/metabolism ; Endosulfan/toxicity ; Oxidative Stress ; Rats ; Rats, Wistar ; Superoxide Dismutase/metabolism
Czasopismo naukowe
Tytuł :
Activated mesangial cells induce glomerular endothelial cells proliferation in rat anti-Thy-1 nephritis through VEGFA/VEGFR2 and Angpt2/Tie2 pathway.
Autorzy :
Zhao Y; Department of Nephrology, First Medical Center of Chinese PLA General Hospital, Nephrology Institute of the Chinese People's Liberation Army, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Disease Research, Beijing, China.; Department of Nephrology, The Second Hospital of Jilin University, Changchun, China.
Fu B; Department of Nephrology, First Medical Center of Chinese PLA General Hospital, Nephrology Institute of the Chinese People's Liberation Army, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Disease Research, Beijing, China.
Chen P; Department of Nephrology, First Medical Center of Chinese PLA General Hospital, Nephrology Institute of the Chinese People's Liberation Army, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Disease Research, Beijing, China.
Li Q; Department of Nephrology, First Medical Center of Chinese PLA General Hospital, Nephrology Institute of the Chinese People's Liberation Army, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Disease Research, Beijing, China.
Ouyang Q; Department of Nephrology, First Medical Center of Chinese PLA General Hospital, Nephrology Institute of the Chinese People's Liberation Army, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Disease Research, Beijing, China.
Zhang C; Department of Nephrology, First Medical Center of Chinese PLA General Hospital, Nephrology Institute of the Chinese People's Liberation Army, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Disease Research, Beijing, China.
Cai G; Department of Nephrology, First Medical Center of Chinese PLA General Hospital, Nephrology Institute of the Chinese People's Liberation Army, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Disease Research, Beijing, China.
Wu L; Department of Nephrology, First Medical Center of Chinese PLA General Hospital, Nephrology Institute of the Chinese People's Liberation Army, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Disease Research, Beijing, China.
Chen X; Department of Nephrology, First Medical Center of Chinese PLA General Hospital, Nephrology Institute of the Chinese People's Liberation Army, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Disease Research, Beijing, China.; Department of Nephrology, The Second Hospital of Jilin University, Changchun, China.
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Źródło :
Cell proliferation [Cell Prolif] 2021 Jun; Vol. 54 (6), pp. e13055. Date of Electronic Publication: 2021 May 13.
Typ publikacji :
Journal Article
MeSH Terms :
Signal Transduction*
Endothelial Cells/*pathology
Glomerulonephritis/*pathology
Kidney Glomerulus/*pathology
Mesangial Cells/*pathology
Thy-1 Antigens/*antagonists & inhibitors
Angiopoietin-2/metabolism ; Animals ; Antibodies ; Cell Proliferation ; Disease Models, Animal ; Endothelial Cells/metabolism ; Glomerulonephritis/chemically induced ; Glomerulonephritis/metabolism ; Kidney Glomerulus/metabolism ; Male ; Mesangial Cells/metabolism ; Rats ; Rats, Wistar ; Receptor, TIE-2/metabolism ; Thy-1 Antigens/metabolism ; Vascular Endothelial Growth Factor A/metabolism ; Vascular Endothelial Growth Factor Receptor-2/metabolism
Czasopismo naukowe
Tytuł :
Identification of the metabolites produced following Iris tectorum Maxim oral administration and a network pharmacology-based analysis of their potential pharmacological properties.
Autorzy :
Liu J; Department of Pharmacy, Yinan People's Hospital, Yinan, Shandong, China.
Xia TR; Guangdong Yi Fang Pharmaceutical Co., Ltd, Foshan, China.
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Źródło :
Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2021 Jun; Vol. 51 (6), pp. 680-688. Date of Electronic Publication: 2021 Apr 07.
Typ publikacji :
Journal Article
MeSH Terms :
Drugs, Chinese Herbal*/pharmacology
Iris Plant*
Plants, Medicinal*
Administration, Oral ; Animals ; Chromatography, High Pressure Liquid ; Molecular Docking Simulation ; Rats ; Rats, Wistar
Czasopismo naukowe

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