Autor: "Rc, Stein" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Computational approaches to support comparative analysis of multiparametric tests: Modelling versus Training.
Autorzy:: Bartlett JMS; Diagnostic Development, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.; Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.; Edinburgh Cancer Research Centre, Edinburgh, United Kingdom.
Bayani J; Diagnostic Development, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.
Kornaga EN; Tom Baker Cancer Centre, Calgary, Alberta, Canada.
Danaher P; Diagnostic Development, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.
Crozier C; Diagnostic Development, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.
Piper T; Edinburgh Cancer Research Centre, Edinburgh, United Kingdom.
Yao CQ; Computational Biology Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.
Dunn JA; Warwick Medical School, University of Warwick, Coventry, United Kingdom.
Boutros PC; Computational Biology Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.; Department of Pharmacology & Toxicology, University of Toronto, Toronto, Ontario, Canada.
Stein RC; UCL (University College London) and National Institute for Health Research University College London Hospitals Biomedical Research Centre, London, United Kingdom.; Pokaż więcej
Corporate Authors:: OPTIMA Trial Management Group
Źródło:: PloS one [PLoS One] 2020 Sep 03; Vol. 15 (9), pp. e0238593. Date of Electronic Publication: 2020 Sep 03 (Print Publication: 2020).
Typ publikacji:: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Breast Neoplasms*/diagnosis
Breast Neoplasms*/genetics
Gene Expression Profiling/*methods
Computer Simulation ; Cost-Benefit Analysis ; Female ; Gene Expression Profiling/economics ; Genomics ; Humans ; Prognosis ; Randomized Controlled Trials as Topic

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Skocz do pozycji: 2.

Tytuł:: Development of a framework to improve the process of recruitment to randomised controlled trials (RCTs): the SEAR (Screened, Eligible, Approached, Randomised) framework.
Autorzy:: Wilson C; School of Social and Community Medicine, University of Bristol, 39 Whatley Road, Bristol, BS8 2PS, UK. .
Rooshenas L; School of Social and Community Medicine, University of Bristol, 39 Whatley Road, Bristol, BS8 2PS, UK.
Paramasivan S; School of Social and Community Medicine, University of Bristol, 39 Whatley Road, Bristol, BS8 2PS, UK.
Elliott D; School of Social and Community Medicine, University of Bristol, 39 Whatley Road, Bristol, BS8 2PS, UK.
Jepson M; School of Social and Community Medicine, University of Bristol, 39 Whatley Road, Bristol, BS8 2PS, UK.
Strong S; School of Social and Community Medicine, University of Bristol, 39 Whatley Road, Bristol, BS8 2PS, UK.
Birtle A; Rosemere Cancer Centre, Royal Preston Hospital, Sharoe Green Land North, Fulwood, Preston, Lancashire, PR2 9HT, UK.
Beard DJ; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, OX3 7LD, UK.
Halliday A; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, OX3 9DU, UK.
Hamdy FC; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, OX3 9DU, UK.
Lewis R; Institute of Cancer Research Clinical Trials and Statistics Unit (ICR-CTSU), Institute of Cancer Research, 15 Cotswold Road, Sutton, SM2 5NG, UK.
Metcalfe C; School of Social and Community Medicine, University of Bristol, 39 Whatley Road, Bristol, BS8 2PS, UK.; Bristol Randomised Trials Collaboration University of Bristol, School of Social and Community Medicine, 39 Whatley Road, Bristol, BS8 2PS, UK.
Rogers CA; Clinical Trials and Evaluation Unit, School of Clinical Sciences, University of Bristol, Level 7 Queens Building, Bristol Royal Infirmary, Bristol, BS2 8HW, UK.
Stein RC; NIHR University College London Hospitals Biomedical Research Centre, 149 Tottenham Court Road, London, W1T 7DN, UK.
Blazeby JM; School of Social and Community Medicine, University of Bristol, 39 Whatley Road, Bristol, BS8 2PS, UK.
Donovan JL; School of Social and Community Medicine, University of Bristol, 39 Whatley Road, Bristol, BS8 2PS, UK.; Collaboration for Leadership in Applied Health Research and Care West, University Hospitals Bristol, 9th Floor, Whitefriars Lewins, Bristol, BS1 2NT, UK.; Pokaż więcej
Źródło:: Trials [Trials] 2018 Jan 19; Vol. 19 (1), pp. 50. Date of Electronic Publication: 2018 Jan 19.
Typ publikacji:: Journal Article
MeSH Terms:: Clinical Decision-Making*
Patient Selection*
Eligibility Determination/*methods
Randomized Controlled Trials as Topic/*methods
Endpoint Determination ; Humans ; Sample Size ; Treatment Outcome

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Skocz do pozycji: 3.

Tytuł:: Informed consent in randomised controlled trials: development and preliminary evaluation of a measure of Participatory and Informed Consent (PIC).
Autorzy:: Wade J; School of Social and Community Medicine, University of Bristol, 39 Whatley Road, Clifton, Bristol, BS8 2PS, UK. .
Elliott D; School of Social and Community Medicine, University of Bristol, 39 Whatley Road, Clifton, Bristol, BS8 2PS, UK.
Avery KNL; School of Social and Community Medicine, University of Bristol, 39 Whatley Road, Clifton, Bristol, BS8 2PS, UK.
Gaunt D; School of Social and Community Medicine, University of Bristol, 39 Whatley Road, Clifton, Bristol, BS8 2PS, UK.
Young GJ; School of Social and Community Medicine, University of Bristol, 39 Whatley Road, Clifton, Bristol, BS8 2PS, UK.
Barnes R; School of Social and Community Medicine, University of Bristol, 39 Whatley Road, Clifton, Bristol, BS8 2PS, UK.
Paramasivan S; School of Social and Community Medicine, University of Bristol, 39 Whatley Road, Clifton, Bristol, BS8 2PS, UK.
Campbell WB; Royal Devon and Exeter Hospital, Exeter, EX2 5DW, UK.
Blazeby JM; School of Social and Community Medicine, University of Bristol, 39 Whatley Road, Clifton, Bristol, BS8 2PS, UK.
Birtle AJ; Rosemere Cancer Centre, Royal Preston Hospital, Sharoe Green Lane North, Fulwood, Preston, Lancashire, PR2 9HT4, UK.; University of Manchester, Oxford Road, Manchester, M13 9PL, UK.
Stein RC; National Institute for Health Research (NIHR), University College London Hospitals (UCLH), Biomedical Research Centre (BMC), University College London Hospitals, 1st Floor Central, 250 Euston Road, London, NW1 2PG, UK.
Beard DJ; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, OX3 7LD, UK.
Halliday AW; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, OX3 9DU, UK.
Donovan JL; School of Social and Community Medicine, University of Bristol, 39 Whatley Road, Clifton, Bristol, BS8 2PS, UK.; National Institute for Health Research Collaboration for Leadership in Applied Health Research and Care (NIHR CLAHRC) West, University Hospitals Bristol NHS Trust, 9th Floor, Whitefriars, Lewins Mead, Bristol, BS1 2NT, UK.; Pokaż więcej
Corporate Authors:: ProtecT study group
CLASS study group
Chemorad study group
POUT study group
OPTIMA prelim study group
CSAW study group and ACST-2 study group
Źródło:: Trials [Trials] 2017 Jul 17; Vol. 18 (1), pp. 327. Date of Electronic Publication: 2017 Jul 17.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Informed Consent*/ethics
Informed Consent*/legislation & jurisprudence
Informed Consent*/standards
Patient Participation*/legislation & jurisprudence
Patient Selection*/ethics
Research Subjects*/legislation & jurisprudence
Research Subjects*/psychology
Surveys and Questionnaires*
Randomized Controlled Trials as Topic/*methods
Access to Information ; Attitude of Health Personnel ; Communication ; Comprehension ; Guidelines as Topic ; Health Knowledge, Attitudes, Practice ; Humans ; Observer Variation ; Psychometrics ; Randomized Controlled Trials as Topic/ethics ; Randomized Controlled Trials as Topic/legislation & jurisprudence ; Randomized Controlled Trials as Topic/standards ; Reproducibility of Results ; Research Personnel/psychology

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Skocz do pozycji: 4.

Tytuł:: Macroscopic handling and reporting of breast cancer specimens pre- and post-neoadjuvant chemotherapy treatment: review of pathological issues and suggested approaches.
Autorzy:: Pinder SE; Research Oncology, Division of Cancer Studies, King's College London, Guy's Hospital, London, UK.
Rakha EA; Division of Cancer and Stem Cells, School of Medicine, University of Nottingham, Nottingham, UK.
Purdie CA; Department of Pathology, Ninewells Hospital and Medical School, Dundee, UK.
Bartlett JM; Ontario Institute for Cancer Research, Toronto, ON, Canada.
Francis A; Queen Elizabeth Hospital Birmingham, Birmingham, UK.
Stein RC; University College London Hospitals and Medical School, London, UK.
Thompson AM; Department of Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Shaaban AM; Department of Cellular Pathology, Queen Elizabeth Hospital Birmingham, Birmingham, UK.; Pokaż więcej
Corporate Authors:: Translational Subgroup of the NCRI Breast Clinical Studies Group
Źródło:: Histopathology [Histopathology] 2015 Sep; Vol. 67 (3), pp. 279-93. Date of Electronic Publication: 2015 Mar 08.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:: Breast Neoplasms/*pathology
Breast Neoplasms/*therapy
Biomarkers, Tumor/metabolism ; Breast Neoplasms/metabolism ; Female ; Humans ; Lymphatic Metastasis/pathology ; Neoadjuvant Therapy ; Prognosis ; Receptor, ErbB-2/metabolism ; Receptors, Estrogen/metabolism

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Skocz do pozycji: 5.

Tytuł:: Adaptive designs for clinical trials assessing biomarker-guided treatment strategies.
Autorzy:: Wason J; MRC Biostatistics Unit, Cambridge, UK.
Marshall A; Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, UK.
Dunn J; Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, UK.
Stein RC; UCLH/UCL NIHR Biomedical Research Centre, London, UK.
Stallard N; Warwick Medical School, University of Warwick, Coventry, UK.; Pokaż więcej
Źródło:: British journal of cancer [Br J Cancer] 2014 Apr 15; Vol. 110 (8), pp. 1950-7. Date of Electronic Publication: 2014 Mar 25.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Precision Medicine*
Breast Neoplasms/*drug therapy
Breast Neoplasms/*genetics
Biomarkers, Tumor/blood ; Breast Neoplasms/blood ; Breast Neoplasms/pathology ; Computer Simulation ; Female ; Humans ; Randomized Controlled Trials as Topic ; Research Design ; Treatment Outcome