Temat: "Reactive Oxygen Species" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Ferrodifferentiation regulates neurodevelopment via ROS generation.
Autorzy:: Chang S; Laboratory of Molecular Iron Metabolism, Ministry of Education Key Laboratory of Molecular and Cellular Biology, Hebei Key Laboratory of Animal Physiology, Biochemistry, and Molecular Biology, College of Life Sciences, Hebei Normal University, Shijiazhuang, 050024, China.; College of Basic Medicine, Hebei Medical University, Shijiazhuang, 050017, China.; State Key Laboratory of Brain and Cognitive Science, CAS Center for Excellence in Brain Science and Intelligence Technology (Shanghai), Institute of Biophysics, Chinese Academy of Sciences (CAS), BNU IDG/McGovern Institute for Brain Research, Beijing, 100101, China.
Wang P; Laboratory of Molecular Iron Metabolism, Ministry of Education Key Laboratory of Molecular and Cellular Biology, Hebei Key Laboratory of Animal Physiology, Biochemistry, and Molecular Biology, College of Life Sciences, Hebei Normal University, Shijiazhuang, 050024, China.; College of Basic Medicine, Hebei Medical University, Shijiazhuang, 050017, China.
Han Y; Laboratory of Molecular Iron Metabolism, Ministry of Education Key Laboratory of Molecular and Cellular Biology, Hebei Key Laboratory of Animal Physiology, Biochemistry, and Molecular Biology, College of Life Sciences, Hebei Normal University, Shijiazhuang, 050024, China.
Ma Q; State Key Laboratory of Brain and Cognitive Science, CAS Center for Excellence in Brain Science and Intelligence Technology (Shanghai), Institute of Biophysics, Chinese Academy of Sciences (CAS), BNU IDG/McGovern Institute for Brain Research, Beijing, 100101, China.
Liu Z; State Key Laboratory of Brain and Cognitive Science, CAS Center for Excellence in Brain Science and Intelligence Technology (Shanghai), Institute of Biophysics, Chinese Academy of Sciences (CAS), BNU IDG/McGovern Institute for Brain Research, Beijing, 100101, China.
Zhong S; State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing, 100875, China.
Lu Y; State Key Laboratory of Brain and Cognitive Science, CAS Center for Excellence in Brain Science and Intelligence Technology (Shanghai), Institute of Biophysics, Chinese Academy of Sciences (CAS), BNU IDG/McGovern Institute for Brain Research, Beijing, 100101, China.
Chen R; State Key Laboratory of Brain and Cognitive Science, CAS Center for Excellence in Brain Science and Intelligence Technology (Shanghai), Institute of Biophysics, Chinese Academy of Sciences (CAS), BNU IDG/McGovern Institute for Brain Research, Beijing, 100101, China.
Sun L; Beijing Institute of Brain Disorders, Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Capital Medical University, Beijing, 100069, China.
Wu Q; State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing, 100875, China.
Gao G; Laboratory of Molecular Iron Metabolism, Ministry of Education Key Laboratory of Molecular and Cellular Biology, Hebei Key Laboratory of Animal Physiology, Biochemistry, and Molecular Biology, College of Life Sciences, Hebei Normal University, Shijiazhuang, 050024, China. .
Wang X; State Key Laboratory of Brain and Cognitive Science, CAS Center for Excellence in Brain Science and Intelligence Technology (Shanghai), Institute of Biophysics, Chinese Academy of Sciences (CAS), BNU IDG/McGovern Institute for Brain Research, Beijing, 100101, China. .
Chang YZ; Laboratory of Molecular Iron Metabolism, Ministry of Education Key Laboratory of Molecular and Cellular Biology, Hebei Key Laboratory of Animal Physiology, Biochemistry, and Molecular Biology, College of Life Sciences, Hebei Normal University, Shijiazhuang, 050024, China. .; Pokaż więcej
Źródło:: Science China. Life sciences [Sci China Life Sci] 2023 Aug; Vol. 66 (8), pp. 1841-1857. Date of Electronic Publication: 2023 Mar 14.
Typ publikacji:: Journal Article
MeSH Terms:: Iron Deficiencies*
Iron-Sulfur Proteins*/metabolism
Reactive Oxygen Species*/metabolism
Animals ; Mice ; Iron/metabolism ; Iron Regulatory Protein 1/metabolism ; Iron Regulatory Protein 2/metabolism

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Skocz do pozycji: 2.

Tytuł:: Systematic identification of anticancer drug targets reveals a nucleus-to-mitochondria ROS-sensing pathway.
Autorzy:: Zhang J; Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA. Electronic address: .
Simpson CM; Cell Signaling Technology, Inc., Danvers, MA, USA.
Berner J; Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA.
Chong HB; Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA.
Fang J; Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA.
Ordulu Z; Department of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, FL, USA.
Weiss-Sadan T; Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA.
Possemato AP; Cell Signaling Technology, Inc., Danvers, MA, USA.
Harry S; Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA.
Takahashi M; Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA.
Yang TY; Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA.
Richter M; Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA.
Patel H; Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA.
Smith AE; Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA.
Carlin AD; Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA.
Hubertus de Groot AF; Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA.
Wolf K; Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA.
Shi L; Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA.
Wei TY; Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA.
Dürr BR; Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA.
Chen NJ; Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA.
Vornbäumen T; Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA.
Wichmann NO; Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA.
Mahamdeh MS; Division of Cardiology, Harvard Medical School, Boston, MA, USA; Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.
Pooladanda V; Department of Obstetrics and Gynecology, Vincent Center for Reproductive Biology, Massachusetts General Hospital, Boston, MA, USA; Obstetrics, Gynecology and Reproductive Biology, Harvard Medical School, Boston, MA, USA.
Matoba Y; Department of Obstetrics and Gynecology, Vincent Center for Reproductive Biology, Massachusetts General Hospital, Boston, MA, USA; Obstetrics, Gynecology and Reproductive Biology, Harvard Medical School, Boston, MA, USA.
Kumar S; Obstetrics, Gynecology and Reproductive Biology, Harvard Medical School, Boston, MA, USA.
Kim E; Obstetrics, Gynecology and Reproductive Biology, Harvard Medical School, Boston, MA, USA.
Bouberhan S; Division of Hematology/Oncology, Massachusetts General Hospital, Boston, MA, USA; Department of Medicine, Massachusetts General Hospital, Boston, MA, USA; Department of Medicine, Harvard Medical School, Boston, MA, USA.
Oliva E; Department of Pathology, Massachusetts General Hospital, Boston, MA, USA.
Rueda BR; Department of Obstetrics and Gynecology, Vincent Center for Reproductive Biology, Massachusetts General Hospital, Boston, MA, USA; Obstetrics, Gynecology and Reproductive Biology, Harvard Medical School, Boston, MA, USA.
Soberman RJ; Division of Nephrology, Harvard Medical School, Boston, MA, USA; Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.
Bardeesy N; Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA; Department of Medicine, Harvard Medical School, Boston, MA, USA.
Liau BB; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.
Lawrence M; Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA; Department of Medicine, Harvard Medical School, Boston, MA, USA.
Stokes MP; Cell Signaling Technology, Inc., Danvers, MA, USA.
Beausoleil SA; Cell Signaling Technology, Inc., Danvers, MA, USA.
Bar-Peled L; Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA; Department of Medicine, Harvard Medical School, Boston, MA, USA. Electronic address: .; Pokaż więcej
Źródło:: Cell [Cell] 2023 May 25; Vol. 186 (11), pp. 2361-2379.e25. Date of Electronic Publication: 2023 May 15.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/metabolism
Reactive Oxygen Species*/metabolism
Hydrogen Peroxide/metabolism ; Mitochondria/metabolism ; Cell Nucleus/metabolism ; Humans

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Skocz do pozycji: 3.

Tytuł:: Acute generation of reactive oxygen species that induced by doxycycline pretreatment results in rapid cell death in polyphyllin G-treated osteosarcoma cell lines.
Autorzy:: Li YA; Institute of Translational Medicine and New Drug Development, School of Medicine, China Medical University, Taichung, Taiwan.; Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan.; Orthopaedic Department, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.; Department of Orthopedic Surgery, Changhua Christian Hospital, Changhua, Taiwan.
Chen HY; Orthopedics & Sports Medicine Laboratory, Changhua Christian Hospital, Changhua, Taiwan.
Hsieh CP; Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan.; Department of Orthopedic Surgery, Changhua Christian Hospital, Changhua, Taiwan.; Orthopedics & Sports Medicine Laboratory, Changhua Christian Hospital, Changhua, Taiwan.; Department of Kinesiology, Health and Leisure Studies, Chienkuo Technology University, Changhua, Taiwan.
Chen CL; Department of Orthopedic Surgery, Changhua Christian Hospital, Changhua, Taiwan.; Department of Nursing, Hungkuang University, Taichung, Taiwan.
Hung SC; Drug Development Center, Institute of Translational Medicine and New Drug Development, School of Medicine, China Medical University, Taichung, Taiwan.; Integrative Stem Cell Center, China Medical University Hospital, Taichung, Taiwan.; Department of Orthopedics, China Medical University Hospital, Taichung, Taiwan.
Huang YF; Orthopedics & Sports Medicine Laboratory, Changhua Christian Hospital, Changhua, Taiwan.; Pokaż więcej
Źródło:: Environmental toxicology [Environ Toxicol] 2023 May; Vol. 38 (5), pp. 1174-1184. Date of Electronic Publication: 2023 Feb 11.
Typ publikacji:: Journal Article
MeSH Terms:: Doxycycline*/pharmacology
Doxycycline*/therapeutic use
Osteosarcoma*/pathology
Reactive Oxygen Species*/metabolism
Saponins*/pharmacology
Saponins*/therapeutic use
Humans ; Apoptosis ; Cell Death ; Cell Line, Tumor

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Skocz do pozycji: 4.

Tytuł:: Myocardial ischemia-reperfusion injury is probably due to the excessive production of mitochondrial ROS caused by the activation of 5-HT degradation system mediated by PAF receptor.
Autorzy:: Jin J; Department of Physiology, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
Xu F; Department of Physiology, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
Zhang Y; Department of Physiology, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
Guan J; Department of Physiology, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing 210009, China.
Fu J; Department of Physiology, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing 210009, China. Electronic address: jihua_.; Pokaż więcej
Źródło:: Molecular immunology [Mol Immunol] 2023 Mar; Vol. 155, pp. 27-43. Date of Electronic Publication: 2023 Jan 20.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Myocardial Reperfusion Injury*/metabolism
Platelet Membrane Glycoproteins*/metabolism
Reactive Oxygen Species*/metabolism
Reactive Oxygen Species*/toxicity
Receptors, G-Protein-Coupled*/metabolism
Serotonin*/metabolism
Serotonin*/pharmacology
Animals ; Rats ; Apoptosis ; Clorgyline/pharmacology ; Monoamine Oxidase/metabolism ; Monoamine Oxidase/pharmacology ; Proto-Oncogene Proteins c-akt/metabolism ; TOR Serine-Threonine Kinases/metabolism

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Skocz do pozycji: 5.

Tytuł:: Overexpression of a Novel Noxo1 Mutant Increases Ros Production and Noxo1 Relocalisation.
Autorzy:: Benssouina FZ; Aix-Marseille Univ, CNRS, INP, Inst Neurophysiopathol, 13005 Marseille, France.
Parat F; Aix-Marseille Univ, CNRS, INP, Inst Neurophysiopathol, 13005 Marseille, France.
Villard C; Aix-Marseille Univ, CNRS, INP, Inst Neurophysiopathol, 13005 Marseille, France.
Leloup L; Aix-Marseille Univ, CNRS, INP, Inst Neurophysiopathol, 13005 Marseille, France.
Garrouste F; Aix-Marseille Univ, CNRS, INP, Inst Neurophysiopathol, 13005 Marseille, France.
Sabatier JM; Aix-Marseille Univ, CNRS, INP, Inst Neurophysiopathol, 13005 Marseille, France.
Ferhat L; Aix-Marseille Univ, CNRS, INP, Inst Neurophysiopathol, 13005 Marseille, France.
Kovacic H; Aix-Marseille Univ, CNRS, INP, Inst Neurophysiopathol, 13005 Marseille, France.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Feb 28; Vol. 24 (5). Date of Electronic Publication: 2023 Feb 28.
Typ publikacji:: Journal Article
MeSH Terms:: Reactive Oxygen Species*/metabolism
Adaptor Proteins, Signal Transducing*/genetics
Adaptor Proteins, Signal Transducing*/metabolism
NADPH Oxidase 1/metabolism ; Cell Line, Tumor ; Humans ; Mutation

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Skocz do pozycji: 6.

Tytuł:: Alantolactone inhibits oesophageal adenocarcinoma cells through nuclear factor erythroid 2-related factor 2-mediated reactive oxygen species increment.
Autorzy:: Chen J; Institute of Materia Medica, School of Pharmacy, North Sichuan Medical College, Nanchong, China.
Zhang Y; School of Basic Medical Sciences & Forensic Medicine, North Sichuan Medical College, Nanchong, China.; Medical imaging Key Laboratory of Sichuan Province, North Sichuan Medical College, Nanchong, China.
Huang R; Institute of Materia Medica, School of Pharmacy, North Sichuan Medical College, Nanchong, China.
Cao L; Institute of Materia Medica, School of Pharmacy, North Sichuan Medical College, Nanchong, China.
Zhang Y; Department of Anesthesiology, School of Clinical Medicine, North Sichuan Medical College, Nanchong, China.
Lian M; Institute of Materia Medica, School of Pharmacy, North Sichuan Medical College, Nanchong, China.; Institute of Tissue Engineering and Stem Cells, Cancer Biotherapy Key Laboratory of Nanchong, Nanchong Central Hospital, The Second Clinical Medical College, North Sichuan Medical College, Nanchong, China.
Wang Z; Institute of Materia Medica, School of Pharmacy, North Sichuan Medical College, Nanchong, China.; Institute of Tissue Engineering and Stem Cells, Cancer Biotherapy Key Laboratory of Nanchong, Nanchong Central Hospital, The Second Clinical Medical College, North Sichuan Medical College, Nanchong, China.
Jin J; Institute of Materia Medica, School of Pharmacy, North Sichuan Medical College, Nanchong, China.; Institute of Tissue Engineering and Stem Cells, Cancer Biotherapy Key Laboratory of Nanchong, Nanchong Central Hospital, The Second Clinical Medical College, North Sichuan Medical College, Nanchong, China.
Tang C; Institute of Materia Medica, School of Pharmacy, North Sichuan Medical College, Nanchong, China.; Institute of Tissue Engineering and Stem Cells, Cancer Biotherapy Key Laboratory of Nanchong, Nanchong Central Hospital, The Second Clinical Medical College, North Sichuan Medical College, Nanchong, China.
Chen T; Medical imaging Key Laboratory of Sichuan Province, North Sichuan Medical College, Nanchong, China.
Yan L; Department of Anesthesiology, School of Clinical Medicine, North Sichuan Medical College, Nanchong, China.
Yu L; Medical imaging Key Laboratory of Sichuan Province, North Sichuan Medical College, Nanchong, China.
Tian R; Institute of Materia Medica, School of Pharmacy, North Sichuan Medical College, Nanchong, China.
Xiang X; Institute of Tissue Engineering and Stem Cells, Cancer Biotherapy Key Laboratory of Nanchong, Nanchong Central Hospital, The Second Clinical Medical College, North Sichuan Medical College, Nanchong, China.
Luo L; Institute of Materia Medica, School of Pharmacy, North Sichuan Medical College, Nanchong, China.
Yu C; Institute of Materia Medica, School of Pharmacy, North Sichuan Medical College, Nanchong, China.; Pokaż więcej
Źródło:: Basic & clinical pharmacology & toxicology [Basic Clin Pharmacol Toxicol] 2023 Mar; Vol. 132 (3), pp. 253-262. Date of Electronic Publication: 2022 Dec 21.
Typ publikacji:: Journal Article
MeSH Terms:: Adenocarcinoma*/drug therapy
Reactive Oxygen Species*/metabolism
Sesquiterpenes, Eudesmane*/pharmacology
Esophageal Neoplasms*/drug therapy
Animals ; Humans ; Mice ; Apoptosis ; Cell Line, Tumor ; Lactones/pharmacology ; Mice, Nude ; NF-E2-Related Factor 2/drug effects ; NF-E2-Related Factor 2/metabolism

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Skocz do pozycji: 7.

Tytuł:: Calpain Regulates Reactive Oxygen Species Production during Capacitation through the Activation of NOX2 and NOX4.
Autorzy:: Ortiz-García CI; Department of Cell Biology, Centro de Investigación y Estudios Avanzados del Instituto Politécnico Nacional, Av. Instituto Politécnico Nacional 2508, San Pedro Zacatenco, Del. Gustavo A. Madero, México City 07360, Mexico.
Salgado-Lucio ML; Department of Cell Biology, Centro de Investigación y Estudios Avanzados del Instituto Politécnico Nacional, Av. Instituto Politécnico Nacional 2508, San Pedro Zacatenco, Del. Gustavo A. Madero, México City 07360, Mexico.; Department of Health Sciences, Universidad Autónoma Metropolitana, División de Ciencias Biológicas y de la Salud, Unidad Iztapalapa, Av. San Rafael Atlixco No. 186, Colonia Vicentina, Alcaldía Iztapalapa, México City 09310, Mexico.
Roa-Espitia AL; Department of Cell Biology, Centro de Investigación y Estudios Avanzados del Instituto Politécnico Nacional, Av. Instituto Politécnico Nacional 2508, San Pedro Zacatenco, Del. Gustavo A. Madero, México City 07360, Mexico.
Muñoz-Sánchez AA; Department of Cell Biology, Centro de Investigación y Estudios Avanzados del Instituto Politécnico Nacional, Av. Instituto Politécnico Nacional 2508, San Pedro Zacatenco, Del. Gustavo A. Madero, México City 07360, Mexico.
Cordero-Martínez J; Department of Biochemistry, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Prolongación Manuel Carpio y Plan de Ayala s/n Col, Santo Tomás, Del. Miguel Hidalgo, México City 11340, Mexico.
Hernández-González EO; Department of Cell Biology, Centro de Investigación y Estudios Avanzados del Instituto Politécnico Nacional, Av. Instituto Politécnico Nacional 2508, San Pedro Zacatenco, Del. Gustavo A. Madero, México City 07360, Mexico.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Feb 16; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 16.
Typ publikacji:: Journal Article
MeSH Terms:: Calpain*/metabolism
Reactive Oxygen Species*/metabolism
Semen*/metabolism
Sperm Capacitation*
Animals ; Guinea Pigs ; Male ; Mice ; NADPH Oxidase 4/metabolism ; NADPH Oxidases/metabolism ; Spermatozoa/metabolism

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Skocz do pozycji: 8.

Tytuł:: Genistein and Procyanidin B2 Reduce Carcinogen-Induced Reactive Oxygen Species and DNA Damage through the Activation of Nrf2/ARE Cell Signaling in Bronchial Epithelial Cells In Vitro.
Autorzy:: Suraweera TL; Department of Plant, Food, and Environmental Sciences, Faculty of Agriculture, Dalhousie University, Truro, NS B2N 2R8, Canada.
Merlin JPJ; Department of Plant, Food, and Environmental Sciences, Faculty of Agriculture, Dalhousie University, Truro, NS B2N 2R8, Canada.
Dellaire G; Department of Pathology, Faculty of Medicine, Dalhousie University, Halifax, NS B3H 4H7, Canada.
Xu Z; Department of Pathology, Faculty of Medicine, Dalhousie University, Halifax, NS B3H 4H7, Canada.; QEII Health Sciences Centre, Division of Anatomical Pathology and Cytopathology, Nova Scotia Health Authority, Halifax, NS B3H 1V8, Canada.
Rupasinghe HPV; Department of Plant, Food, and Environmental Sciences, Faculty of Agriculture, Dalhousie University, Truro, NS B2N 2R8, Canada.; Department of Pathology, Faculty of Medicine, Dalhousie University, Halifax, NS B3H 4H7, Canada.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Feb 12; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 12.
Typ publikacji:: Journal Article
MeSH Terms:: Carcinogens*/pharmacology
Epithelial Cells*/drug effects
Epithelial Cells*/metabolism
Genistein*/pharmacology
Proto-Oncogene Proteins c-akt*/metabolism
Reactive Oxygen Species*/metabolism
Proanthocyanidins*/pharmacology
Humans ; Antioxidant Response Elements/drug effects ; DNA Damage/drug effects ; Flavonoids/pharmacology ; NF-E2-Related Factor 2/metabolism ; Oxidative Stress ; Quercetin/pharmacology ; Signal Transduction

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Skocz do pozycji: 9.

Tytuł:: Rutin ameliorates gout via reducing XOD activity, inhibiting ROS production and NLRP3 inflammasome activation in quail.
Autorzy:: Wu H; Department of Clinical Chinese Pharmacy, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, PR China.
Wang Y; Department of Clinical Chinese Pharmacy, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, PR China.
Huang J; Department of Clinical Chinese Pharmacy, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, PR China.
Li Y; Department of Clinical Chinese Pharmacy, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, PR China.
Lin Z; Department of Clinical Chinese Pharmacy, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, PR China; Center for Pharmacovigilance and Rational Use of Chinese Medicine, Beijing University of Chinese Medicine, Beijing, PR China.
Zhang B; Department of Clinical Chinese Pharmacy, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, PR China; Center for Pharmacovigilance and Rational Use of Chinese Medicine, Beijing University of Chinese Medicine, Beijing, PR China. Electronic address: .; Pokaż więcej
Źródło:: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2023 Feb; Vol. 158, pp. 114175. Date of Electronic Publication: 2022 Dec 30.
Typ publikacji:: Journal Article
MeSH Terms:: Gout*/drug therapy
Gout*/metabolism
Inflammasomes*/metabolism
Reactive Oxygen Species*/metabolism
Rutin*/pharmacology
Animals ; Inflammation/drug therapy ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Uric Acid/pharmacology ; Quail

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Skocz do pozycji: 10.

Tytuł:: ROS induced the Rab26 promoter hypermethylation to promote cigarette smoking-induced airway epithelial inflammation of COPD through activation of MAPK signaling.
Autorzy:: He BF; Department of Pulmonary and Critical Care Medicine, Zhongshan Hospital, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
Wu YX; Department of Pulmonary and Critical Care Medicine, Zhongshan Hospital, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
Hu WP; Department of Pulmonary and Critical Care Medicine, Zhongshan Hospital, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
Hua JL; Department of Pulmonary and Critical Care Medicine, Zhongshan Hospital, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
Han Y; Department of Pulmonary and Critical Care Medicine, Zhongshan Hospital, Shanghai Medical College, Fudan University, Shanghai, 200032, China.
Zhang J; Department of Pulmonary and Critical Care Medicine, Zhongshan Hospital, Shanghai Medical College, Fudan University, Shanghai, 200032, China. Electronic address: .; Pokaż więcej
Źródło:: Free radical biology & medicine [Free Radic Biol Med] 2023 Feb 01; Vol. 195, pp. 359-370. Date of Electronic Publication: 2023 Jan 05.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cigarette Smoking*/adverse effects
Pulmonary Disease, Chronic Obstructive*/genetics
Pulmonary Disease, Chronic Obstructive*/metabolism
rab GTP-Binding Proteins*/genetics
rab GTP-Binding Proteins*/metabolism
Reactive Oxygen Species*/metabolism
Humans ; DNA Methylation ; Epithelial Cells/metabolism ; Hydrogen Peroxide/metabolism ; Inflammation/chemically induced ; Inflammation/genetics ; Inflammation/metabolism

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Skocz do pozycji: 11.

Tytuł:: ROS-CCL5 axis recruits CD8 T lymphocytes promoting the apoptosis of granulosa cells in diminished ovary reserve.
Autorzy:: Zhao N; Center for Human Reproduction and Genetics, Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou 215002, China; State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing 210029, China.
Zhang C; Center for Human Reproduction and Genetics, Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou 215002, China; State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing 210029, China.
Wu Y; Center for Human Reproduction and Genetics, Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou 215002, China; State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing 210029, China.
Ding J; Center for Human Reproduction and Genetics, Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou 215002, China; State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing 210029, China.
Wang F; Center for Human Reproduction and Genetics, Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou 215002, China; State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing 210029, China.
Cheng W; Center for Human Reproduction and Genetics, Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou 215002, China; State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing 210029, China.
Li H; Center for Human Reproduction and Genetics, Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou 215002, China; State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing 210029, China. Electronic address: .
Zhu R; Center for Human Reproduction and Genetics, Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou 215002, China; State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing 210029, China. Electronic address: .; Pokaż więcej
Źródło:: Journal of reproductive immunology [J Reprod Immunol] 2023 Feb; Vol. 155, pp. 103789. Date of Electronic Publication: 2022 Dec 29.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: CD8-Positive T-Lymphocytes*/metabolism
Chemokine CCL5*/metabolism
Ovary*/metabolism
Ovary*/pathology
Reactive Oxygen Species*/metabolism
Female ; Humans ; Apoptosis ; Follicular Atresia ; Granulosa Cells/metabolism ; Granulosa Cells/pathology ; Hydrogen Peroxide/metabolism

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Skocz do pozycji: 12.

Tytuł:: Novel molecular photosensitizer with simultaneously GSH depletion, aggregation inhibition and accelerated elimination for improved and safe photodynamic therapy.
Autorzy:: Chen J; National and Local Joint Biomedical Engineering Research Center on Photodynamic Technologies, College of Chemistry, Fuzhou University, Fuzhou, 350116, Fujian, China. Electronic address: .
Yan M; National and Local Joint Biomedical Engineering Research Center on Photodynamic Technologies, College of Chemistry, Fuzhou University, Fuzhou, 350116, Fujian, China.
Huang K; National and Local Joint Biomedical Engineering Research Center on Photodynamic Technologies, College of Chemistry, Fuzhou University, Fuzhou, 350116, Fujian, China.
Xue J; National and Local Joint Biomedical Engineering Research Center on Photodynamic Technologies, College of Chemistry, Fuzhou University, Fuzhou, 350116, Fujian, China.; Pokaż więcej
Źródło:: European journal of medicinal chemistry [Eur J Med Chem] 2023 Jan 05; Vol. 245 (Pt 1), pp. 114938. Date of Electronic Publication: 2022 Nov 21.
Typ publikacji:: Journal Article
MeSH Terms:: Glutathione*/antagonists & inhibitors
Maleimides*/chemistry
Maleimides*/pharmacology
Photosensitizing Agents*/chemistry
Photosensitizing Agents*/pharmacology
Reactive Oxygen Species*/antagonists & inhibitors
Antineoplastic Agents*/chemistry
Antineoplastic Agents*/pharmacology
Photochemotherapy/methods ; Humans ; Hep G2 Cells

Czasopismo naukowe

na półce

Szczegóły

Skocz do pozycji: 13.

Tytuł:: Discovery of novel hydroxyamidine based indoleamine 2,3-dioxygenase 1 (IDO1) and thioredoxin reductase 1 (TrxR1) dual inhibitors.
Autorzy:: Zhou J; Center for Reproductive Medicine, The First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui, 241000, PR China; Center of Drug Screening and Evaluation, Wannan Medical College, Wuhu, Anhui, 241000, PR China.
Yu LZ; School of Pharmacy, Wannan Medical College, Wuhu, Anhui, 241000, PR China.
Fan YL; Center of Drug Screening and Evaluation, Wannan Medical College, Wuhu, Anhui, 241000, PR China.
Guo CH; Center of Drug Screening and Evaluation, Wannan Medical College, Wuhu, Anhui, 241000, PR China.
Lv XM; Center of Drug Screening and Evaluation, Wannan Medical College, Wuhu, Anhui, 241000, PR China.
Zhou ZY; Center of Drug Screening and Evaluation, Wannan Medical College, Wuhu, Anhui, 241000, PR China.
Huang HD; Center of Drug Screening and Evaluation, Wannan Medical College, Wuhu, Anhui, 241000, PR China.
Miao DD; Center of Drug Screening and Evaluation, Wannan Medical College, Wuhu, Anhui, 241000, PR China.
Zhang SP; Center of Drug Screening and Evaluation, Wannan Medical College, Wuhu, Anhui, 241000, PR China.
Li XY; Department of Clinical Pharmacy, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, Jiangsu, 210009, PR China.
Zhao PP; Department of Clinical Pharmacy, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, Jiangsu, 210009, PR China.
Liu XP; Center of Drug Screening and Evaluation, Wannan Medical College, Wuhu, Anhui, 241000, PR China. Electronic address: .
Hu WH; Center for Reproductive Medicine, The First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui, 241000, PR China. Electronic address: .
Zhang C; Center of Drug Screening and Evaluation, Wannan Medical College, Wuhu, Anhui, 241000, PR China. Electronic address: .; Pokaż więcej
Źródło:: European journal of medicinal chemistry [Eur J Med Chem] 2023 Jan 05; Vol. 245 (Pt 1), pp. 114860. Date of Electronic Publication: 2022 Oct 29.
Typ publikacji:: Journal Article
MeSH Terms:: Enzyme Inhibitors*/chemistry
Enzyme Inhibitors*/pharmacology
Indoleamine-Pyrrole 2,3,-Dioxygenase*/antagonists & inhibitors
Reactive Oxygen Species*
Thioredoxin Reductase 1*/antagonists & inhibitors
Colorectal Neoplasms*/enzymology
Cell Line, Tumor ; Humans ; Apoptosis/drug effects

Czasopismo naukowe

na półce

Szczegóły

Skocz do pozycji: 14.

Tytuł:: Hypomagnetic Field Exposure Affecting Gut Microbiota, Reactive Oxygen Species Levels, and Colonic Cell Proliferation in Mice.
Autorzy:: Zhan A; Key Laboratory of Earth and Planetary Physics, Institute of Geology and Geophysics, Chinese Academy of Sciences, Beijing, China.; France-China Joint Laboratory for Evolution and Development of Magnetotactic Multicellular Organisms, Chinese Academy of Sciences, Beijing, China.; College of Earth and Planetary Sciences, University of Chinese Academy of Sciences, Beijing, China.
Luo Y; Key Laboratory of Earth and Planetary Physics, Institute of Geology and Geophysics, Chinese Academy of Sciences, Beijing, China.; France-China Joint Laboratory for Evolution and Development of Magnetotactic Multicellular Organisms, Chinese Academy of Sciences, Beijing, China.; College of Earth and Planetary Sciences, University of Chinese Academy of Sciences, Beijing, China.
Qin H; College of Earth and Planetary Sciences, University of Chinese Academy of Sciences, Beijing, China.; State Key Laboratory of Lithospheric Evolution, Institute of Geology and Geophysics, Chinese Academy of Sciences, Beijing, China.
Lin W; Key Laboratory of Earth and Planetary Physics, Institute of Geology and Geophysics, Chinese Academy of Sciences, Beijing, China.; France-China Joint Laboratory for Evolution and Development of Magnetotactic Multicellular Organisms, Chinese Academy of Sciences, Beijing, China.
Tian L; Key Laboratory of Earth and Planetary Physics, Institute of Geology and Geophysics, Chinese Academy of Sciences, Beijing, China.; France-China Joint Laboratory for Evolution and Development of Magnetotactic Multicellular Organisms, Chinese Academy of Sciences, Beijing, China.; Pokaż więcej
Źródło:: Bioelectromagnetics [Bioelectromagnetics] 2022 Dec; Vol. 43 (8), pp. 462-475. Date of Electronic Publication: 2022 Nov 26.
Typ publikacji:: Journal Article
MeSH Terms:: Colon*
Gastrointestinal Microbiome*
Reactive Oxygen Species*
Animals ; Mice ; Cell Proliferation ; Mice, Inbred C57BL

Czasopismo naukowe

na półce

Szczegóły

Skocz do pozycji: 15.

Tytuł:: Peroxiredoxin 5 overexpression decreases oxidative stress and dopaminergic cell death mediated by paraquat.
Autorzy:: Duarte-Jurado AP; Departamento de Histologia, Facultad de Medicina, Universidad Autonoma de Nuevo Leon, Monterrey 64460, Nuevo Leon, Mexico.
Loera-Arias MJ; Departamento de Histologia, Facultad de Medicina, Universidad Autonoma de Nuevo Leon, Monterrey 64460, Nuevo Leon, Mexico.
Saucedo-Cardenas O; Departamento de Histologia, Facultad de Medicina, Universidad Autonoma de Nuevo Leon, Monterrey 64460, Nuevo Leon, Mexico.
Montes de Oca-Luna R; Departamento de Histologia, Facultad de Medicina, Universidad Autonoma de Nuevo Leon, Monterrey 64460, Nuevo Leon, Mexico.
Rodriguez-Rocha H; Departamento de Histologia, Facultad de Medicina, Universidad Autonoma de Nuevo Leon, Monterrey 64460, Nuevo Leon, Mexico. Electronic address: .
Garcia-Garcia A; Departamento de Histologia, Facultad de Medicina, Universidad Autonoma de Nuevo Leon, Monterrey 64460, Nuevo Leon, Mexico. Electronic address: .; Pokaż więcej
Źródło:: Cells & development [Cells Dev] 2023 Sep; Vol. 175, pp. 203860. Date of Electronic Publication: 2023 Jun 01.
Typ publikacji:: Journal Article
MeSH Terms:: Paraquat*/pharmacology
Oxidative Stress*
Animals ; Humans ; Reactive Oxygen Species/metabolism ; Reactive Oxygen Species/pharmacology ; Peroxiredoxins/genetics ; Peroxiredoxins/metabolism ; Peroxiredoxins/pharmacology ; Cell Death/genetics

Czasopismo naukowe

na półce

Szczegóły

Skocz do pozycji: 16.

Tytuł:: Histone-deacetylase-inhibitory effects of periodontopathic-bacterial metabolites induce human gingival epithelial Ca9-22 cell death.
Autorzy:: Uemichi K; Division of Oral Structural and Functional Biology, Nihon University Graduate School of Dentistry, Tokyo, Japan.; Department of Oral and Maxillofacial Surgery I, Nihon University School of Dentistry, Tokyo, Japan.
Mikami Y; Division of Microscopic Anatomy, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Watanabe T; Department of Chemistry, Nihon University School of Dentistry, Tokyo, Japan.
Shinozuka K; Department of Oral and Maxillofacial Surgery I, Nihon University School of Dentistry, Tokyo, Japan.
Tonogi M; Department of Oral and Maxillofacial Surgery I, Nihon University School of Dentistry, Tokyo, Japan.
Tsuda H; Department of Biochemistry, Nihon University School of Dentistry, 1-8-13 Kanda-Surugadai, Chiyoda-ku, Tokyo, 101-8310, Japan. .; Division of Functional Morphology, Dental Research Center, Nihon University School of Dentistry, Tokyo, Japan. .; Pokaż więcej
Źródło:: Odontology [Odontology] 2023 Jul; Vol. 111 (3), pp. 658-667. Date of Electronic Publication: 2022 Dec 08.
Typ publikacji:: Journal Article
MeSH Terms:: Histones*/metabolism
Histones*/pharmacology
Propionates*/pharmacology
Humans ; Histone Deacetylase Inhibitors/pharmacology ; Histone Deacetylases/metabolism ; Histone Deacetylases/pharmacology ; Reactive Oxygen Species/metabolism ; Reactive Oxygen Species/pharmacology ; Epithelial Cells/metabolism ; Butyrates/metabolism ; Butyrates/pharmacology ; Cell Death ; Bacteria ; Carbonic Anhydrase IX/metabolism ; Carbonic Anhydrase IX/pharmacology ; Antigens, Neoplasm/pharmacology

Czasopismo naukowe

na półce

Szczegóły

Skocz do pozycji: 17.

Tytuł:: Short-Term In Vitro ROS Detection and Oxidative Stress Regulators in Epiretinal Membranes and Vitreous from Idiopathic Vitreoretinal Diseases.
Autorzy:: Balzamino BO; Research Laboratories in Ophthalmology, IRCCS-Fondazione Bietti, Rome, Italy.
Dinice L; Research Laboratories in Ophthalmology, IRCCS-Fondazione Bietti, Rome, Italy.
Cacciamani A; Retinal Unit, IRCCS-Fondazione Bietti, Rome, Italy.
Re A; Università Cattolica del Sacro Cuore, Rome, Italy.
Scarinci F; Retinal Unit, IRCCS-Fondazione Bietti, Rome, Italy.
Bruno L; Research Laboratories in Ophthalmology, IRCCS-Fondazione Bietti, Rome, Italy.
Cosimi P; Retinal Unit, IRCCS-Fondazione Bietti, Rome, Italy.
Micera A; Research Laboratories in Ophthalmology, IRCCS-Fondazione Bietti, Rome, Italy.; Pokaż więcej
Źródło:: BioMed research international [Biomed Res Int] 2022 Dec 16; Vol. 2022, pp. 7497816. Date of Electronic Publication: 2022 Dec 16 (Print Publication: 2022).
Typ publikacji:: Journal Article
MeSH Terms:: Epiretinal Membrane*/genetics
Epiretinal Membrane*/metabolism
Reactive Oxygen Species*/metabolism
Oxidative Stress*/genetics
Oxidative Stress*/physiology
Humans ; Interleukin-18/metabolism ; Kelch-Like ECH-Associated Protein 1/metabolism ; NF-E2-Related Factor 2/metabolism ; Vascular Endothelial Growth Factor A/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 18.

Tytuł:: TRAF3/p38-JNK Signalling Crosstalk with Intracellular-TRAIL/Caspase-10-Induced Apoptosis Accelerates ROS-Driven Cancer Cell-Specific Death by CD40.
Autorzy:: Ibraheem K; Department of Biological Sciences, School of Applied Sciences, University of Huddersfield, Queensgate, Huddersfield HD1 3DH, UK.
Yhmed AMA; Department of Biological Sciences, School of Applied Sciences, University of Huddersfield, Queensgate, Huddersfield HD1 3DH, UK.; Department of Medical Laboratory Sciences, Faculty of Medical Technology, Wadi Alshatti University, Wadi Alshatti P.O. Box 68, Libya.
Nasef MM; Department of Biological Sciences, School of Applied Sciences, University of Huddersfield, Queensgate, Huddersfield HD1 3DH, UK.
Georgopoulos NT; Department of Biological Sciences, School of Applied Sciences, University of Huddersfield, Queensgate, Huddersfield HD1 3DH, UK.; Pokaż więcej
Źródło:: Cells [Cells] 2022 Oct 18; Vol. 11 (20). Date of Electronic Publication: 2022 Oct 18.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Apoptosis*
CD40 Antigens*/metabolism
Reactive Oxygen Species*/metabolism
TNF Receptor-Associated Factor 3*/metabolism
TNF-Related Apoptosis-Inducing Ligand*/metabolism
p38 Mitogen-Activated Protein Kinases*/metabolism
MAP Kinase Kinase 4*
Colorectal Neoplasms*/metabolism
Colorectal Neoplasms*/pathology
Humans ; Caspase 10/metabolism ; CD40 Ligand/metabolism ; MAP Kinase Kinase Kinase 5/metabolism ; NADPH Oxidases/metabolism ; BH3 Interacting Domain Death Agonist Protein/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 19.

Tytuł:: Myocardial-Targeting Tannic Cerium Nanocatalyst Attenuates Ischemia/Reperfusion Injury.
Autorzy:: Wang L; Shanghai Institute of Ceramics, Chinese Academy of Sciences, Research Unit of Nanocatalytic Medicine in Specific Therapy for Serious Disease, Chinese Academy of Medical Sciences (2021RU012), Shanghai, 200050, P. R. China.; Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.
Qiu S; Shanghai Tenth People's Hospital, Shanghai Frontiers Science Center of Nanocatalytic Medicine, School of Medicine, Tongji University, Shanghai, 200072, P. R. China.
Li X; Department of Anesthesiology, West China Hospital of Sichuan University, Chengdu, 610041, China.
Zhang Y; Department of Anesthesiology, West China Hospital of Sichuan University, Chengdu, 610041, China.
Huo M; Shanghai Tenth People's Hospital, Shanghai Frontiers Science Center of Nanocatalytic Medicine, School of Medicine, Tongji University, Shanghai, 200072, P. R. China.
Shi J; Shanghai Institute of Ceramics, Chinese Academy of Sciences, Research Unit of Nanocatalytic Medicine in Specific Therapy for Serious Disease, Chinese Academy of Medical Sciences (2021RU012), Shanghai, 200050, P. R. China.; Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.; Shanghai Tenth People's Hospital, Shanghai Frontiers Science Center of Nanocatalytic Medicine, School of Medicine, Tongji University, Shanghai, 200072, P. R. China.; Pokaż więcej
Źródło:: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2023 Sep 25; Vol. 62 (39), pp. e202305576. Date of Electronic Publication: 2023 Jul 11.
Typ publikacji:: Journal Article
MeSH Terms:: Myocardial Reperfusion Injury*/drug therapy
Myocardial Infarction*/metabolism
Mice ; Animals ; Reactive Oxygen Species/metabolism ; Myocardium/metabolism ; Myocytes, Cardiac/metabolism ; Oxidative Stress

Czasopismo naukowe

na półce

Szczegóły

Skocz do pozycji: 20.

Tytuł:: Evaluating β-cryptoxanthin antioxidant properties against ROS-induced macromolecular damages and determining its photo-stability and in-vitro SPF.
Autorzy:: Brahma D; Department of Biotechnology, National Institute of Technology, Durgapur, WB, 713209, India.
Dutta D; Department of Biotechnology, National Institute of Technology, Durgapur, WB, 713209, India. .; Pokaż więcej
Źródło:: World journal of microbiology & biotechnology [World J Microbiol Biotechnol] 2023 Sep 16; Vol. 39 (11), pp. 310. Date of Electronic Publication: 2023 Sep 16.
Typ publikacji:: Journal Article
MeSH Terms:: Antioxidants*/pharmacology
Beta-Cryptoxanthin*
Reactive Oxygen Species ; DNA Damage ; Hydrogen

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